首页 > 最新文献

Nepal Mediciti Medical Journal最新文献

英文 中文
Anthropozoonotic transmission of Monkeypox: Are our canine companions at risk? 猴痘的人畜共患传播:我们的犬类同伴有危险吗?
Pub Date : 2022-12-31 DOI: 10.3126/nmmj.v3i2.52365
J. Robinson, Indrajit Banerjee, Alexandra Leclézio
Monkeypox is the latest zoonotic outbreak spreading in its majority throughout the Western region of the globe. The latest statistics and reports indicate that Spain, France, Germany, Portugal and the Netherlands are the country’s worst effected with a total of 7083, 3897, 3570, 845 and 1221 cases respectively. The WHO has also reported numerous cases extending into the Balkans and Turkey. The current global Monkeypox outbreak is becoming more concerning as the total number of cases globally has surpassed 35000, and the incident rates are accelerating with a 20% growth in cases being noted on a weekly basis. This global increase in cases intern enhances exposure of the virus to a larger portion of the populous; the exposure of the virus is not only intensified in humans but also their household pets and animals.
猴痘是最新的人畜共患疾病暴发,主要在全球西部地区传播。最新统计和报告显示,西班牙、法国、德国、葡萄牙和荷兰疫情最严重,分别为7083例、3897例、3570例、845例和1221例。世界卫生组织还报告了许多蔓延到巴尔干和土耳其的病例。目前全球猴痘疫情正变得更加令人担忧,因为全球病例总数已超过3.5万例,而且发病率正在加快,每周发现的病例数增长20%。全球实习病例的增加增加了病毒对更大一部分人口的暴露;不仅在人类中,而且在他们的家庭宠物和动物中,病毒暴露加剧。
{"title":"Anthropozoonotic transmission of Monkeypox: Are our canine companions at risk?","authors":"J. Robinson, Indrajit Banerjee, Alexandra Leclézio","doi":"10.3126/nmmj.v3i2.52365","DOIUrl":"https://doi.org/10.3126/nmmj.v3i2.52365","url":null,"abstract":"Monkeypox is the latest zoonotic outbreak spreading in its majority throughout the Western region of the globe. The latest statistics and reports indicate that Spain, France, Germany, Portugal and the Netherlands are the country’s worst effected with a total of 7083, 3897, 3570, 845 and 1221 cases respectively. The WHO has also reported numerous cases extending into the Balkans and Turkey. The current global Monkeypox outbreak is becoming more concerning as the total number of cases globally has surpassed 35000, and the incident rates are accelerating with a 20% growth in cases being noted on a weekly basis. This global increase in cases intern enhances exposure of the virus to a larger portion of the populous; the exposure of the virus is not only intensified in humans but also their household pets and animals.","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131753933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective Study on transfusion requirements and deep vein thrombosis incidence with the use of Tranexamic acid on total knee replacement 全膝关节置换术中使用氨甲环酸对输血需求和深静脉血栓发生率的回顾性研究
Pub Date : 2022-12-31 DOI: 10.3126/nmmj.v3i2.52361
R. Rana, S. Lakhey, D. Jha, N. Chitrakar, J. Thakur, A. Poudel
BACKGROUND Total knee replacement is often associated with significant blood loss and increased rate of blood transfusion. Tranexamic acid is a potent anti-fibrinolytic agent and its use in major surgeries has shown to decrease blood loss as well as transfusion rates. It is used intravenous, oral and topical forms as well. This study aims to find out the effectiveness of systemic Tranexamic acid in terms of decrease in transfusion rate as well incidence of deep vein thrombosis (DVT) and thromboembolism. MATERIALS AND METHODS Total number of patients were 94 of which 58 had bilateral knees replacement and 36 patient underwent unilateral knee replacement over the period of 3 years (December 2018 –December 2021). All patients were screened for general condition as well as any coagulopathy pre –op. All patients were given IV form of Tranexamic acid followed by oral form for 3 days post operatively. Tourniquet was used in all cases and low molecular weight heparin (Clexane) 40 mg subcutaneous once a day for 1-2 days followed by oral aspirin was given for 6 weeks to all patients. SCD calf pumps were used for 4 to 5 days. RESULTS We found that incidence of blood transfusion was only 6.9% in our case series which was well within the incidence reported in varied literature on the use of Tranexamic acid in knee replacement surgery. There was no clinical feature of deep vein thrombosis / pulmonary embolism (DVT/PE) in any of our patients. CONCLUSION Use of Tranexamic acid is a safe and effective method for controlling blood loss and decreasing the transfusion rate after total knee replacement surgery. Its intravenous and oral forms are readily available and cost effective. Its use is not associated with DVT or PE.
背景:全膝关节置换术常伴有大量失血和输血率增加。氨甲环酸是一种有效的抗纤溶剂,在大手术中使用它可以减少失血和输血率。它可以静脉注射、口服和外用。本研究旨在了解全身氨甲环酸在降低输血率、深静脉血栓形成(DVT)和血栓栓塞发生率方面的有效性。材料与方法在2018年12月至2021年12月的3年期间,共94例患者,其中58例患者行双侧膝关节置换术,36例患者行单侧膝关节置换术。所有患者术前均筛查一般情况及任何凝血功能障碍。所有患者术后静脉注射氨甲环酸,口服3天。所有患者均予止血带治疗,同时给予低分子肝素40mg (Clexane)皮下注射,每天1次,持续1-2天,随后给予阿司匹林口服,持续6周。SCD小牛泵使用4 - 5天。结果:我们发现,在我们的病例系列中,输血的发生率仅为6.9%,这与各种文献中关于在膝关节置换手术中使用氨甲环酸的报道的发生率完全一致。所有患者均无深静脉血栓/肺栓塞(DVT/PE)的临床特征。结论氨甲环酸是控制全膝关节置换术后失血量和降低输血率的一种安全有效的方法。它的静脉注射和口服形式很容易获得,而且成本低廉。它的使用与DVT或PE无关。
{"title":"Retrospective Study on transfusion requirements and deep vein thrombosis incidence with the use of Tranexamic acid on total knee replacement","authors":"R. Rana, S. Lakhey, D. Jha, N. Chitrakar, J. Thakur, A. Poudel","doi":"10.3126/nmmj.v3i2.52361","DOIUrl":"https://doi.org/10.3126/nmmj.v3i2.52361","url":null,"abstract":"BACKGROUND Total knee replacement is often associated with significant blood loss and increased rate of blood transfusion. Tranexamic acid is a potent anti-fibrinolytic agent and its use in major surgeries has shown to decrease blood loss as well as transfusion rates. It is used intravenous, oral and topical forms as well. This study aims to find out the effectiveness of systemic Tranexamic acid in terms of decrease in transfusion rate as well incidence of deep vein thrombosis (DVT) and thromboembolism. \u0000MATERIALS AND METHODS Total number of patients were 94 of which 58 had bilateral knees replacement and 36 patient underwent unilateral knee replacement over the period of 3 years (December 2018 –December 2021). All patients were screened for general condition as well as any coagulopathy pre –op. All patients were given IV form of Tranexamic acid followed by oral form for 3 days post operatively. Tourniquet was used in all cases and low molecular weight heparin (Clexane) 40 mg subcutaneous once a day for 1-2 days followed by oral aspirin was given for 6 weeks to all patients. SCD calf pumps were used for 4 to 5 days. \u0000RESULTS We found that incidence of blood transfusion was only 6.9% in our case series which was well within the incidence reported in varied literature on the use of Tranexamic acid in knee replacement surgery. There was no clinical feature of deep vein thrombosis / pulmonary embolism (DVT/PE) in any of our patients. \u0000CONCLUSION Use of Tranexamic acid is a safe and effective method for controlling blood loss and decreasing the transfusion rate after total knee replacement surgery. Its intravenous and oral forms are readily available and cost effective. Its use is not associated with DVT or PE.","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128086799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An observational study on emerging antimicrobial resistance pattern in urinary tract Infection in Nepalese children 尼泊尔儿童尿路感染新出现的抗菌药物耐药模式的观察研究
Pub Date : 2022-12-31 DOI: 10.3126/nmmj.v3i2.52341
S. Bhandari, Anna Sharma, Ankita Guragain, S. Sapkota
AIMS Evidence-based management and local antibiotic susceptibility pattern provides evidence to guide the development of urinary tract infection (UTI) treatments protocols decreasing the economic burden significantly. We aimed to investigate the aetiology and resistance pattern of bacterial uropathogens to commonly prescribed oral antibiotics (beta lactamase and fluoroquinolones) causing UTI and to recommend the most appropriate antibiotics. MATERIALS AND METHODS This study is cross sectional, retrospective study. We evaluated causative agents and antimicrobial resistance in urine, culture positive samples collected from July 2019 to June 2021 in a single hospital in Kathmandu, Nepal. To obtain urine samples, a midstream clean-catch method used in children who were toilet trained and transurethral catheterization performed in non-toilet-trained children. Urine samples were sent to the laboratory where they were inoculated using a 4 mm calibre loop on CLED (Cysteine Lactose Electrolyte Deficient) agar plate, and incubated at 37 °C for 18–24 h. Conventional methods (colony morphology, Gram stain) were opted. Different biochemical tests – catalase test, coagulase test and inoculation in Bile Esculin Agar was done for Gram-positive organisms, while Triple Sugar Indole (TSI) agar, Sulphide indole motility (SIM) agar, Simon's citrate agar and Christensen's urea agar were used for identification of Gram-negative bacilli. Significant growth was evaluated as ≥105 colony forming units (CFU)/ml of urine. Kirby-Bauer disc diffusion method was used to perform in vitro antimicrobial susceptibility tests in Mueller-Hinton agar plates. Total 13 drugs were tested for sensitivity pattern. To analyse resistance to antibiotics for different ages, subjects were divided into four age groups: Group I, 2 months - 1 year; Group II, 1 year - 5 year; Group III, 5 year - 10 year; Group IV, 10 year - 15 year. RESULTS Among 970 samples sent, a total of 230 positive urine cultures were identified, of which 116 (50.4%) were from girls and 114 (49.6%) were from boys. The most common age group was 2 months to 1 year (49.1%). The most common causative agent was Escherichia coli (49.1%) followed by Enterococcus faecalis (14.3%) and Klebsiella pneumoniae (11.3%). The overall resistance to Nalidixic acid (66%), Ceftriaxone (54.8%) Cefotaxime (48.3%) Ciprofloxacin (47.9%) and Co-trimoxazole (46.9%) was significant. The least resistance was for Chloramphenicol, Nitrofurantoin, and Norfloxacin was 9.5 %, 31.5 %, and 38.3 % respectively. Chloramphenicol (90.5%) was the most active agent against E. coli and Klebsiella, whereas Linezolid (92.7%) and cloxacillin (64.9%) was most active against Enterococcus and Staphylococcus species. CONCLUSION Escherichia coli was the most common causative agent of urinary tract infection in children. Nalidixic acid, Ceftriaxone, Cefotaxime, Ciprofloxacin and Co-trimoxazole had the highest resistance rates against urinary tract pathogens in our centre.
目的循证管理和局部抗生素药敏模式为指导尿路感染(UTI)治疗方案的制定提供依据,显著减轻经济负担。本研究旨在探讨尿路感染的细菌性尿路病原体对常用口服抗生素(β -内酰胺酶和氟喹诺酮类药物)的病原学和耐药模式,并推荐最合适的抗生素。材料与方法本研究为横断面、回顾性研究。我们评估了2019年7月至2021年6月在尼泊尔加德满都一家医院收集的尿液、培养阳性样本中的病原体和抗菌素耐药性。为获取尿样,在接受如厕训练的儿童中采用中游清洁法,在未接受如厕训练的儿童中采用经尿道导尿法。将尿液样本送到实验室,在cle(半胱氨酸乳糖电解质缺乏)琼脂板上使用4 mm口径的环接种,并在37℃下孵育18-24小时。选择常规方法(菌落形态学,革兰氏染色)。革兰氏阳性菌采用不同的生化试验——过氧化氢酶试验、凝固酶试验和接种胆汁液琼脂,革兰氏阴性菌采用三糖吲哚琼脂(TSI)、硫化物吲哚运动琼脂(SIM)、西蒙柠檬酸琼脂和克里斯滕森尿素琼脂进行鉴定。≥105个菌落形成单位(CFU)/ml尿液为显著生长。采用Kirby-Bauer圆盘扩散法在Mueller-Hinton琼脂平板上进行体外药敏试验。对13种药物进行敏感性试验。为了分析不同年龄段患者对抗生素的耐药性,将受试者分为4个年龄组:I组,2个月~ 1岁;第二组,1年至5年;第三组,5年至10年;第四组,10 - 15年。结果在送出的970份样本中,共检出尿培养阳性230例,其中女孩116例(50.4%),男孩114例(49.6%)。最常见的年龄组为2个月至1岁(49.1%)。最常见的病原体是大肠杆菌(49.1%),其次是粪肠球菌(14.3%)和肺炎克雷伯菌(11.3%)。对纳利地酸(66%)、头孢曲松(54.8%)、头孢噻肟(48.3%)、环丙沙星(47.9%)、复方新诺明(46.9%)的总体耐药情况比较显著。氯霉素、呋喃妥因和诺氟沙星的耐药率最低,分别为9.5%、31.5%和38.3%。氯霉素(90.5%)对大肠杆菌和克雷伯菌的抑菌活性最高,利奈唑胺(92.7%)和氯西林(64.9%)对肠球菌和葡萄球菌的抑菌活性最高。结论大肠杆菌是儿童尿路感染最常见的病原体。纳利地酸、头孢曲松、头孢噻肟、环丙沙星和复方新诺明对尿路病原菌的耐药率最高。对于口服经验性抗生素治疗,对于大肠杆菌和克雷伯菌,氯霉素是最合适的选择,对于肠球菌,利奈唑胺是最合适的选择。
{"title":"An observational study on emerging antimicrobial resistance pattern in urinary tract Infection in Nepalese children","authors":"S. Bhandari, Anna Sharma, Ankita Guragain, S. Sapkota","doi":"10.3126/nmmj.v3i2.52341","DOIUrl":"https://doi.org/10.3126/nmmj.v3i2.52341","url":null,"abstract":"AIMS Evidence-based management and local antibiotic susceptibility pattern provides evidence to guide the development of urinary tract infection (UTI) treatments protocols decreasing the economic burden significantly. We aimed to investigate the aetiology and resistance pattern of bacterial uropathogens to commonly prescribed oral antibiotics (beta lactamase and fluoroquinolones) causing UTI and to recommend the most appropriate antibiotics. \u0000MATERIALS AND METHODS This study is cross sectional, retrospective study. We evaluated causative agents and antimicrobial resistance in urine, culture positive samples collected from July 2019 to June 2021 in a single hospital in Kathmandu, Nepal. To obtain urine samples, a midstream clean-catch method used in children who were toilet trained and transurethral catheterization performed in non-toilet-trained children. Urine samples were sent to the laboratory where they were inoculated using a 4 mm calibre loop on CLED (Cysteine Lactose Electrolyte Deficient) agar plate, and incubated at 37 °C for 18–24 h. Conventional methods (colony morphology, Gram stain) were opted. Different biochemical tests – catalase test, coagulase test and inoculation in Bile Esculin Agar was done for Gram-positive organisms, while Triple Sugar Indole (TSI) agar, Sulphide indole motility (SIM) agar, Simon's citrate agar and Christensen's urea agar were used for identification of Gram-negative bacilli. Significant growth was evaluated as ≥105 colony forming units (CFU)/ml of urine. Kirby-Bauer disc diffusion method was used to perform in vitro antimicrobial susceptibility tests in Mueller-Hinton agar plates. Total 13 drugs were tested for sensitivity pattern. To analyse resistance to antibiotics for different ages, subjects were divided into four age groups: Group I, 2 months - 1 year; Group II, 1 year - 5 year; Group III, 5 year - 10 year; Group IV, 10 year - 15 year. \u0000RESULTS Among 970 samples sent, a total of 230 positive urine cultures were identified, of which 116 (50.4%) were from girls and 114 (49.6%) were from boys. The most common age group was 2 months to 1 year (49.1%). The most common causative agent was Escherichia coli (49.1%) followed by Enterococcus faecalis (14.3%) and Klebsiella pneumoniae (11.3%). The overall resistance to Nalidixic acid (66%), Ceftriaxone (54.8%) Cefotaxime (48.3%) Ciprofloxacin (47.9%) and Co-trimoxazole (46.9%) was significant. The least resistance was for Chloramphenicol, Nitrofurantoin, and Norfloxacin was 9.5 %, 31.5 %, and 38.3 % respectively. Chloramphenicol (90.5%) was the most active agent against E. coli and Klebsiella, whereas Linezolid (92.7%) and cloxacillin (64.9%) was most active against Enterococcus and Staphylococcus species. \u0000CONCLUSION Escherichia coli was the most common causative agent of urinary tract infection in children. Nalidixic acid, Ceftriaxone, Cefotaxime, Ciprofloxacin and Co-trimoxazole had the highest resistance rates against urinary tract pathogens in our centre. ","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116314538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of the Presenting Glasgow Coma Scale in patients who requires ICU admission or operative intervention following traumatic brain injury with the Marshall computed tomography (CT) classification of traumatic brain injury 创伤性脑损伤后需要ICU住院或手术干预的患者的格拉斯哥昏迷评分与创伤性脑损伤的Marshall计算机断层扫描(CT)分类的关系
Pub Date : 2022-09-20 DOI: 10.3126/nmmj.v3i1.48520
Sumit Joshi, P. Paudel, D. B. Shah, Prasanna Karki, G. Sharma
BACKGROUND Glasgow coma scale (GCS) and Marshall computed tomography classification of traumatic brain injury can predict the severity of the brain injury in patients following trauma. This study aims to analyse the association between two, in patients who required ICU admission or neurosurgical intervention following trauma. METHODOLOGY Retrospective study of 64 patients who underwent ICU admission or neurosurgical intervention following traumatic brain injury from September 2017 to December 2020 in Nepal Mediciti Hospital. Majority of the mild head injury where CT scan was not performed, discharged from the emergency or did not need ICU admission or admitted in ward for observation, severe polytrauma were excluded from the study. Glasgow coma Scale was categorized into mild (13-15), moderate (9-12) and severe (<8). The Marshall CT scan Grade was dichotomized into (1-3) and (4-6). RESULTS Out 64 patients, majority were male 48 (84.4%), mean age 42.33 (SD±16.16). In admitted patients, 48.4 %( GCS< 8), 39.1% (GCS 9-12), 12.5% (GCS 13-15).The higher marshal grade (4-6) was present in 93.54 %( <8), 48% (9-12), 25% (13-15). There was significant association of the GCS with the Marshall CT scan grade (p=0.00). CONCLUSION There is significant association between the presenting GCS and Marshall CT Scan grade following TBI. The more severe patients with decreasing GCS have higher Marshall CT Scan grade in CT scan of the brain.  
背景:创伤性脑损伤的格拉斯哥昏迷评分(GCS)和马歇尔计算机断层扫描分级可以预测创伤后患者脑损伤的严重程度。本研究旨在分析创伤后需要ICU住院或神经外科干预的患者两者之间的关系。方法回顾性分析2017年9月至2020年12月尼泊尔美第奇蒂医院收治的64例颅脑外伤患者。大多数未进行CT扫描的轻度颅脑损伤,急诊出院或不需要ICU住院或住院观察,严重多发伤均被排除在研究之外。格拉斯哥昏迷评分分为轻度(13-15)、中度(9-12)和重度(<8)。马歇尔CT扫描分级分为(1-3)和(4-6)。结果64例患者中,男性48例(84.4%),平均年龄42.33岁(SD±16.16)。入院患者中,GCS< 8者占48.4%,GCS 9-12者占39.1%,GCS 13-15者占12.5%。较高元帅等级(4 ~ 6)的占93.54%(<8),48%(9 ~ 12),25%(13 ~ 15)。GCS与Marshall CT扫描分级有显著相关性(p=0.00)。结论颅脑损伤后GCS表现与Marshall CT分级有显著相关性。GCS下降越严重的患者,其脑部CT扫描的Marshall CT分级越高。
{"title":"Association of the Presenting Glasgow Coma Scale in patients who requires ICU admission or operative intervention following traumatic brain injury with the Marshall computed tomography (CT) classification of traumatic brain injury","authors":"Sumit Joshi, P. Paudel, D. B. Shah, Prasanna Karki, G. Sharma","doi":"10.3126/nmmj.v3i1.48520","DOIUrl":"https://doi.org/10.3126/nmmj.v3i1.48520","url":null,"abstract":"BACKGROUND Glasgow coma scale (GCS) and Marshall computed tomography classification of traumatic brain injury can predict the severity of the brain injury in patients following trauma. This study aims to analyse the association between two, in patients who required ICU admission or neurosurgical intervention following trauma. \u0000METHODOLOGY Retrospective study of 64 patients who underwent ICU admission or neurosurgical intervention following traumatic brain injury from September 2017 to December 2020 in Nepal Mediciti Hospital. Majority of the mild head injury where CT scan was not performed, discharged from the emergency or did not need ICU admission or admitted in ward for observation, severe polytrauma were excluded from the study. Glasgow coma Scale was categorized into mild (13-15), moderate (9-12) and severe (<8). The Marshall CT scan Grade was dichotomized into (1-3) and (4-6). \u0000RESULTS Out 64 patients, majority were male 48 (84.4%), mean age 42.33 (SD±16.16). In admitted patients, 48.4 %( GCS< 8), 39.1% (GCS 9-12), 12.5% (GCS 13-15).The higher marshal grade (4-6) was present in 93.54 %( <8), 48% (9-12), 25% (13-15). There was significant association of the GCS with the Marshall CT scan grade (p=0.00). \u0000CONCLUSION There is significant association between the presenting GCS and Marshall CT Scan grade following TBI. The more severe patients with decreasing GCS have higher Marshall CT Scan grade in CT scan of the brain.  ","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124814741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Holter Monitoring in assessing Cardiac Arrhythmias in Symptomatic Patients: A Prospective Observational Study 动态心电图监测评估有症状患者心律失常:一项前瞻性观察研究
Pub Date : 2022-09-20 DOI: 10.3126/nmmj.v3i1.48523
B. Karki, J. Ghimire, B. Nepal, A. Mahaseth, A. Sah, Swapnil Pandit, N. Pandey, P. Shah, P. Karki
BACKGROUND The 24hr ECG Holter monitoring system is helpful in assessing cardiac arrhythmias in patients presenting with palpitation, dizziness, presyncope and syncope, which are not detected by standard office electrocardiogram. METHODS This was a single center prospective observational study conducted to assess the prevalence of cardiac arrhythmias among 78 patients consisting of 41 males and 37 females referred for 24 hr ECG Holter monitoring in BPKIHS, Dharan, Nepal, between October 2021 to December 2021. RESULTS The most common indication for 24 hr ECG Holter monitoring in these patients was unexplained palpitation. Ventricular ectopics were the most common arrhythmias detected, followed by supraventricular ectopics, most of which were benign. Among 18 patients with significant bradyarrhythmia, 3 had sinus bradycardia with significant pause, 3 had AF with significant pause, and 2 had high grade/complete AV block. CONCLUSIONS The study showed that most of the arrhythmias detected are benign and prevalence of potentially fatal ventricular and supraventricular tachyarrythmias are relatively low in our population.  
背景24小时动态心电图监测系统有助于评估以心悸、头晕、晕厥前期和晕厥为表现的患者的心律失常,这些是标准办公室心电图无法检测到的。方法:这是一项单中心前瞻性观察性研究,旨在评估2021年10月至2021年12月在尼泊尔达兰BPKIHS进行24小时动态心电图监测的78名患者(41名男性和37名女性)的心律失常患病率。结果24小时动态心电图监测最常见的指征是原因不明的心悸。室性异位是最常见的心律失常,其次是室上异位,大多数是良性的。在18例明显慢性心律失常患者中,3例为窦性心动过缓伴明显暂停,3例为房颤伴明显暂停,2例为高级别/完全房室传导阻滞。结论:该研究表明,大多数检测到的心律失常是良性的,潜在致命性室性和室上性心动过速在我国人群中的患病率相对较低。
{"title":"Holter Monitoring in assessing Cardiac Arrhythmias in Symptomatic Patients: A Prospective Observational Study","authors":"B. Karki, J. Ghimire, B. Nepal, A. Mahaseth, A. Sah, Swapnil Pandit, N. Pandey, P. Shah, P. Karki","doi":"10.3126/nmmj.v3i1.48523","DOIUrl":"https://doi.org/10.3126/nmmj.v3i1.48523","url":null,"abstract":"BACKGROUND The 24hr ECG Holter monitoring system is helpful in assessing cardiac arrhythmias in patients presenting with palpitation, dizziness, presyncope and syncope, which are not detected by standard office electrocardiogram. \u0000METHODS This was a single center prospective observational study conducted to assess the prevalence of cardiac arrhythmias among 78 patients consisting of 41 males and 37 females referred for 24 hr ECG Holter monitoring in BPKIHS, Dharan, Nepal, between October 2021 to December 2021. \u0000RESULTS The most common indication for 24 hr ECG Holter monitoring in these patients was unexplained palpitation. Ventricular ectopics were the most common arrhythmias detected, followed by supraventricular ectopics, most of which were benign. Among 18 patients with significant bradyarrhythmia, 3 had sinus bradycardia with significant pause, 3 had AF with significant pause, and 2 had high grade/complete AV block. \u0000CONCLUSIONS The study showed that most of the arrhythmias detected are benign and prevalence of potentially fatal ventricular and supraventricular tachyarrythmias are relatively low in our population.  ","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133415130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous Intestinal Perforation in a Full Term Neonate: A Case Report 足月新生儿自发性肠穿孔1例
Pub Date : 2022-09-20 DOI: 10.3126/nmmj.v3i1.48527
D. Dhungana, R. Shrestha, R. Ghimire, S. Joshi
Spontaneous intestinal perforation suggests a perforation of the gastrointestinal tract of no demonstrable cause. Only few such cases have been described in full term newborns. Although some authors have suggested ischemia and fetal or neonatal hypoxia as the most likely cause, the etiology and pathogenesis of this disease are still widely unknown. Here, we present a case of Spontaneous intestinal perforation in a full term neonate who was born to a mother with chronic hypertension. Radiological images revealed pneumoperitoneum on a three day old baby with feeding intolerance and abdominal distention. There was no clinical evidence of Hirschsprung’s disease, necrotizing enterocolitis, anorectal malformations or bowel obstruction. An emergency laparotomy revealed a localized perforation in distal ileum. Histopathological examination failed to reveal any etiology for the perforation. The neonate recovered rapidly following a double barrel ileostomy, with no immediate gastrointestinal complications.
自发性肠穿孔指没有明确原因的胃肠道穿孔。在足月新生儿中只有少数这样的病例。虽然一些作者认为缺血和胎儿或新生儿缺氧是最可能的原因,但该病的病因和发病机制仍然广泛未知。在这里,我们提出一个病例自发性肠穿孔在足月新生儿谁是出生的母亲与慢性高血压。放射图像显示气腹,三天大的婴儿喂养不耐受和腹胀。无先天性巨结肠病、坏死性小肠结肠炎、肛肠畸形或肠梗阻的临床证据。紧急剖腹手术发现回肠远端局部穿孔。组织病理学检查未发现穿孔的任何病因。新生儿在双管回肠造口术后恢复迅速,无立即胃肠道并发症。
{"title":"Spontaneous Intestinal Perforation in a Full Term Neonate: A Case Report","authors":"D. Dhungana, R. Shrestha, R. Ghimire, S. Joshi","doi":"10.3126/nmmj.v3i1.48527","DOIUrl":"https://doi.org/10.3126/nmmj.v3i1.48527","url":null,"abstract":"Spontaneous intestinal perforation suggests a perforation of the gastrointestinal tract of no demonstrable cause. Only few such cases have been described in full term newborns. Although some authors have suggested ischemia and fetal or neonatal hypoxia as the most likely cause, the etiology and pathogenesis of this disease are still widely unknown. Here, we present a case of Spontaneous intestinal perforation in a full term neonate who was born to a mother with chronic hypertension. Radiological images revealed pneumoperitoneum on a three day old baby with feeding intolerance and abdominal distention. There was no clinical evidence of Hirschsprung’s disease, necrotizing enterocolitis, anorectal malformations or bowel obstruction. An emergency laparotomy revealed a localized perforation in distal ileum. Histopathological examination failed to reveal any etiology for the perforation. The neonate recovered rapidly following a double barrel ileostomy, with no immediate gastrointestinal complications.","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130068707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-COVID-19 sino-orbital mucormycosis: a case report covid -19后眶内毛霉菌病1例报告
Pub Date : 2022-09-20 DOI: 10.3126/nmmj.v3i1.48525
M. Chaudhary, Chandani Baranwal, R. Pant, S. Chhetri, T. Kc, G. Aryal
Mucormycosis is an invasive fungal infection caused by fungi of the order Mucorales. Mucorales fungi are ubiquitous in environment in association with decaying organic matter. Here we report the case of a 68-year old female who presented with history of ptosis of the left eye with decreased vision, facial pain and loss of sensation in the left cheek. She had history of COVID-19 infection. Magnetic resonances imaging of the brain revealed intense enhancement of left optic nerve. Bilateral spenoidal, ethmoidal and left maxillary sinus showed mucosal thickening. Histopathological and microbiological examination of the specimen confirmed the case of invasive mucormycosis. Despite treatment, patient died at 7th day of hospitalization.  
毛霉菌病是由毛霉菌目真菌引起的侵袭性真菌感染。真菌在环境中普遍存在,与腐烂的有机物有关。我们在此报告一位68岁的女性病患,她有左眼上睑下垂、视力下降、面部疼痛及左颊感觉丧失的病史。她有COVID-19感染史。脑磁共振成像显示左侧视神经强烈增强。双侧蝶窦、筛窦及左侧上颌窦粘膜增厚。标本的组织病理学和微生物学检查证实为侵袭性毛霉病。尽管治疗,患者在住院第7天死亡。
{"title":"Post-COVID-19 sino-orbital mucormycosis: a case report","authors":"M. Chaudhary, Chandani Baranwal, R. Pant, S. Chhetri, T. Kc, G. Aryal","doi":"10.3126/nmmj.v3i1.48525","DOIUrl":"https://doi.org/10.3126/nmmj.v3i1.48525","url":null,"abstract":"Mucormycosis is an invasive fungal infection caused by fungi of the order Mucorales. Mucorales fungi are ubiquitous in environment in association with decaying organic matter. Here we report the case of a 68-year old female who presented with history of ptosis of the left eye with decreased vision, facial pain and loss of sensation in the left cheek. She had history of COVID-19 infection. Magnetic resonances imaging of the brain revealed intense enhancement of left optic nerve. Bilateral spenoidal, ethmoidal and left maxillary sinus showed mucosal thickening. Histopathological and microbiological examination of the specimen confirmed the case of invasive mucormycosis. Despite treatment, patient died at 7th day of hospitalization.  ","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125530899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Pharmacist Intervention on Improving Knowledge, Attitude and Practice among Hypothyroid Patients 药师干预对改善甲状腺功能减退患者知识、态度和行为的影响
Pub Date : 2022-09-20 DOI: 10.3126/nmmj.v3i1.48518
A. Yadav, Sunita Gupta, R. Piryani
BACKGROUND Hypothyroidism causes considerable morbidity. Lack of awareness can lead to poor disease management. This study aimed to investigate the effect of pharmacist-provided counselling in terms of knowledge, attitude, and practice outcomes in hypothyroid patients. METHODS This was a prospective interventional study conducted in a tertiary care hospital of Nepal from September 2019 to February 2020. Based on the inclusion and exclusion criteria, a total of 94 hypothyroid patients were enrolled in this study. Simple Random sampling technique was used. The study population was divided into a test group and control group. The knowledge, attitude, and practice of patients regarding hypothyroidism were assessed and recorded at baseline using questionnaire and counselling was done. After one-month follow-up patients were again assessed using same questionnaire. Data was analyzed using Statistical Package for the Social Sciences version 25. RESULTS The mean knowledge, attitude, and practice scores before intervention of the test group were 6.16±2.14, 18.90±2.29 and 4.53±1.12 respectively, and these scores were changed to 12.48±1.53, 22.04±0.92 and 6.00±0.00 respectively, after the intervention (p < 0.05). Likewise, the mean knowledge, attitude, and practice scores of the control group at baseline were 8.90 ± 3.69, 18.85 ± 2.01 and 4.71 ± 1.29 respectively, and after one-month follow-up the mean scores were changed to 7.88 ± 0.77, 11.50 ± 1.59 and 4.40 ± 0.76 respectively. CONCLUSION The pharmacist-provided counselling is useful in enhancing the knowledge, attitude, and practice of hypothyroid patients.
背景:甲状腺功能减退症的发病率很高。缺乏认识可能导致疾病管理不善。本研究旨在探讨药师提供的咨询对甲状腺功能减退患者的知识、态度和实践结果的影响。方法本研究是2019年9月至2020年2月在尼泊尔一家三级医院进行的前瞻性介入研究。根据纳入和排除标准,本研究共纳入94例甲状腺功能减退患者。采用简单随机抽样技术。研究人群分为试验组和对照组。通过问卷调查和咨询,评估和记录患者关于甲状腺功能减退的知识、态度和行为。随访1个月后,再次使用相同的问卷对患者进行评估。数据分析使用统计软件包的社会科学版本25。结果实验组干预前知识、态度、实践得分均值分别为6.16±2.14、18.90±2.29和4.53±1.12,干预后分别为12.48±1.53、22.04±0.92和6.00±0.00,差异有统计学意义(p < 0.05)。对照组的知识、态度和实践得分在基线时分别为8.90±3.69分、18.85±2.01分和4.71±1.29分,随访1个月后分别为7.88±0.77分、11.50±1.59分和4.40±0.76分。结论药师辅导有助于提高对甲状腺功能减退患者的认识、态度和行为。
{"title":"Impact of Pharmacist Intervention on Improving Knowledge, Attitude and Practice among Hypothyroid Patients","authors":"A. Yadav, Sunita Gupta, R. Piryani","doi":"10.3126/nmmj.v3i1.48518","DOIUrl":"https://doi.org/10.3126/nmmj.v3i1.48518","url":null,"abstract":"BACKGROUND Hypothyroidism causes considerable morbidity. Lack of awareness can lead to poor disease management. This study aimed to investigate the effect of pharmacist-provided counselling in terms of knowledge, attitude, and practice outcomes in hypothyroid patients. \u0000METHODS This was a prospective interventional study conducted in a tertiary care hospital of Nepal from September 2019 to February 2020. Based on the inclusion and exclusion criteria, a total of 94 hypothyroid patients were enrolled in this study. Simple Random sampling technique was used. The study population was divided into a test group and control group. The knowledge, attitude, and practice of patients regarding hypothyroidism were assessed and recorded at baseline using questionnaire and counselling was done. After one-month follow-up patients were again assessed using same questionnaire. Data was analyzed using Statistical Package for the Social Sciences version 25. \u0000RESULTS The mean knowledge, attitude, and practice scores before intervention of the test group were 6.16±2.14, 18.90±2.29 and 4.53±1.12 respectively, and these scores were changed to 12.48±1.53, 22.04±0.92 and 6.00±0.00 respectively, after the intervention (p < 0.05). Likewise, the mean knowledge, attitude, and practice scores of the control group at baseline were 8.90 ± 3.69, 18.85 ± 2.01 and 4.71 ± 1.29 respectively, and after one-month follow-up the mean scores were changed to 7.88 ± 0.77, 11.50 ± 1.59 and 4.40 ± 0.76 respectively. \u0000CONCLUSION The pharmacist-provided counselling is useful in enhancing the knowledge, attitude, and practice of hypothyroid patients.","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114667264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of clinical profile and outcome of patients with snake envenomation at Bheri Hospital Nepal 尼泊尔Bheri医院蛇中毒患者的临床概况和预后研究
Pub Date : 2022-09-20 DOI: 10.3126/nmmj.v3i1.48524
R. Mandal, Nirmal Shakya, Sanket Kumar Risal, Kuldip Goit
BACKGROUND Snake bite is a public health problem in terai and inner terai of Nepal. It is a medical emergency leading to significant morbidity and mortality every year. This study aims to find the clinical profile and outcome of snake bite envenomation patients in Bheri Hospital Nepalgunj. METHODS This was a cross sectional, observational study from April 2021 to November 2021. Patients with history of snake bite and clinical features suggesting envenomation were enrolled in this study, their clinical data and outcome were recorded in Excel sheet and analyzed by SPSS 20. RESULTS A total of 58 cases of snake envenomation was admitted and managed, out of which 3 cases expired with case fatality of 5.17%. Krait and cobra were the common snake bites in this region. 84.48% of the snake bites occur inside houses and more than half 53.44% of the patients were bitten between 12am to 6am. The most common features of envenomation were ptosis, blurring of vision, swallowing difficulty, dysphonia, neck muscle weakness, epigastric pain and salivation. Majority of cases 96.55% was given 10 vials of Anti snake venom (ASV). Only 4 patients 6.89% needed ventilator assistance. CONCLUSION Mortality with snake bites can be minimized by strengthening the treatment centers and readily availability of ASV at such centers. Public awareness about snake bite, first aid, rapid transport to health facilities would be the key to success in reducing morbidity and mortality.  
背景:蛇咬伤是尼泊尔泰莱和内泰莱地区的一个公共卫生问题。这是一种每年导致大量发病率和死亡率的医疗紧急情况。本研究旨在了解尼泊尔百里医院毒蛇咬伤中毒病人的临床情况及转归。方法:这是一项横断面观察性研究,研究时间为2021年4月至2021年11月。本研究纳入有蛇咬伤史和提示中毒的临床特征的患者,将其临床资料及转归记录在Excel表格中,并使用SPSS 20进行分析。结果共收治蛇中毒58例,其中死亡3例,病死率5.17%。该地区最常见的蛇咬伤是水蛇和眼镜蛇。84.48%的患者发生在室内,超过一半的患者发生在凌晨12点至6点之间。中毒最常见的特征是上睑下垂、视力模糊、吞咽困难、发音困难、颈部肌肉无力、上腹痛和流涎。96.55%的病例给予10瓶抗蛇毒(ASV)。只有4例患者需要呼吸机辅助。结论加强治疗中心建设,提高治疗中心ASV的可及性,可降低蛇咬伤死亡率。公众对蛇咬伤、急救和迅速送往卫生设施的认识将是成功降低发病率和死亡率的关键。
{"title":"Study of clinical profile and outcome of patients with snake envenomation at Bheri Hospital Nepal","authors":"R. Mandal, Nirmal Shakya, Sanket Kumar Risal, Kuldip Goit","doi":"10.3126/nmmj.v3i1.48524","DOIUrl":"https://doi.org/10.3126/nmmj.v3i1.48524","url":null,"abstract":"BACKGROUND Snake bite is a public health problem in terai and inner terai of Nepal. It is a medical emergency leading to significant morbidity and mortality every year. This study aims to find the clinical profile and outcome of snake bite envenomation patients in Bheri Hospital Nepalgunj. \u0000METHODS This was a cross sectional, observational study from April 2021 to November 2021. Patients with history of snake bite and clinical features suggesting envenomation were enrolled in this study, their clinical data and outcome were recorded in Excel sheet and analyzed by SPSS 20. \u0000RESULTS A total of 58 cases of snake envenomation was admitted and managed, out of which 3 cases expired with case fatality of 5.17%. Krait and cobra were the common snake bites in this region. 84.48% of the snake bites occur inside houses and more than half 53.44% of the patients were bitten between 12am to 6am. The most common features of envenomation were ptosis, blurring of vision, swallowing difficulty, dysphonia, neck muscle weakness, epigastric pain and salivation. Majority of cases 96.55% was given 10 vials of Anti snake venom (ASV). Only 4 patients 6.89% needed ventilator assistance. \u0000CONCLUSION Mortality with snake bites can be minimized by strengthening the treatment centers and readily availability of ASV at such centers. Public awareness about snake bite, first aid, rapid transport to health facilities would be the key to success in reducing morbidity and mortality.  ","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125921296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Demographic Profile of White-coat Hypertension in the Patients Visiting a Tertiary Care Center in Eastern Nepal 尼泊尔东部三级保健中心白大褂高血压患者的患病率和人口统计特征
Pub Date : 2022-09-20 DOI: 10.3126/nmmj.v3i1.48522
J. Ghimire, B. Karki, B. Nepal, A. Mahaseth, A. Sah, Swapnil Pandit, N. Pandey, P. Shah, P. Karki
BACKGROUND: There is unequivocal evidence showing that at hospital environment BP levels are usually different from measures found at other settings. Therefore, ambulatory BP is expected to be more dependable, as well as allow the identification of a relevant subgroup of white-coat hypertension patient. METHODS: This was a single center descriptive cross-sectional study conducted to assess the prevalence of white-coat hypertension among 50 participants consisting of 31 males and 19 females referred for 24 hour Ambulatory BP monitoring in BPKIHS, Dharan, Nepal, between October 2021 to December 2021. RESULTS: The prevalence of white-coat hypertension was 19 (32%) among 50 participants, while 31(62%) of them had sustained hypertension. Prevalence of WCHTN and sustained hypertension in young age ≤35 years was 4 (21.1%) and 10 (32.3%) respectively, similarly middle age 36-54 years was 13(68.4%) and 16(51.6%) and elderly ≥55 years was 2(10.5%) and 5(16.1%) respectively. Most participants were of middle age group 36-54 years’ age. While of sex distribution pattern of WCHTN and sustained hypertension, male was 11(57.9%) and 20 (64.5%) respectively and female was 8(36.8%) and 15(48.4%) respectively. The association between the demographic variables age, sex and BMI and white-coat HTN was not statistically significant. CONCLUSION: The study showed that White-coat hypertension was more common in male patients and in middle age group 36-54 years, but was not statistically significant. Prevalence of white-coat hypertension was 19(38%). There was no significant association between white-coat hypertension and demographic variables.  
背景:有明确的证据表明,在医院环境中的血压水平通常不同于在其他环境中发现的测量值。因此,动态血压有望更加可靠,并允许识别相关的白大褂高血压患者亚群。方法:这是一项单中心描述性横断面研究,旨在评估2021年10月至2021年12月期间在尼泊尔达兰BPKIHS进行24小时动态血压监测的50名参与者(31名男性和19名女性)的白大衣高血压患病率。结果:50名参与者中有19人(32%)患有白大褂高血压,其中31人(62%)患有持续性高血压。青年人≤35岁WCHTN和持续性高血压患病率分别为4(21.1%)和10(32.3%),中年人36-54岁分别为13(68.4%)和16(51.6%),老年人≥55岁分别为2(10.5%)和5(16.1%)。大多数参与者为36-54岁的中年人。在WCHTN和持续性高血压的性别分布中,男性分别为11例(57.9%)和20例(64.5%),女性分别为8例(36.8%)和15例(48.4%)。人口统计学变量年龄、性别、BMI与白大褂HTN的相关性无统计学意义。结论:研究显示,白大衣高血压在男性患者和36-54岁中年人群中更为常见,但无统计学意义。白大衣高血压的患病率为19(38%)。白大褂高血压与人口统计学变量之间无显著相关性。
{"title":"Prevalence and Demographic Profile of White-coat Hypertension in the Patients Visiting a Tertiary Care Center in Eastern Nepal","authors":"J. Ghimire, B. Karki, B. Nepal, A. Mahaseth, A. Sah, Swapnil Pandit, N. Pandey, P. Shah, P. Karki","doi":"10.3126/nmmj.v3i1.48522","DOIUrl":"https://doi.org/10.3126/nmmj.v3i1.48522","url":null,"abstract":"BACKGROUND: There is unequivocal evidence showing that at hospital environment BP levels are usually different from measures found at other settings. Therefore, ambulatory BP is expected to be more dependable, as well as allow the identification of a relevant subgroup of white-coat hypertension patient. \u0000METHODS: This was a single center descriptive cross-sectional study conducted to assess the prevalence of white-coat hypertension among 50 participants consisting of 31 males and 19 females referred for 24 hour Ambulatory BP monitoring in BPKIHS, Dharan, Nepal, between October 2021 to December 2021. \u0000RESULTS: The prevalence of white-coat hypertension was 19 (32%) among 50 participants, while 31(62%) of them had sustained hypertension. Prevalence of WCHTN and sustained hypertension in young age ≤35 years was 4 (21.1%) and 10 (32.3%) respectively, similarly middle age 36-54 years was 13(68.4%) and 16(51.6%) and elderly ≥55 years was 2(10.5%) and 5(16.1%) respectively. Most participants were of middle age group 36-54 years’ age. While of sex distribution pattern of WCHTN and sustained hypertension, male was 11(57.9%) and 20 (64.5%) respectively and female was 8(36.8%) and 15(48.4%) respectively. The association between the demographic variables age, sex and BMI and white-coat HTN was not statistically significant. \u0000CONCLUSION: The study showed that White-coat hypertension was more common in male patients and in middle age group 36-54 years, but was not statistically significant. Prevalence of white-coat hypertension was 19(38%). There was no significant association between white-coat hypertension and demographic variables.  ","PeriodicalId":131440,"journal":{"name":"Nepal Mediciti Medical Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116761072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Nepal Mediciti Medical Journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1