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SunText Review of Pharmaceutical Sciences最新文献

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An Overview on Buccal Drug Delivery System 口腔给药系统研究进展
Pub Date : 1900-01-01 DOI: 10.51737/2766-5232.2021.009
Mubarak Zo, H. F.
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引用次数: 1
Multiple used Medicinal Plant: Glycyrrhiza Glabra 多用途药用植物:甘草
Pub Date : 1900-01-01 DOI: 10.51737/2766-5232.2021.011
M. M, Sharma P, Mohsina Fp, Faheem Ip, K. R., P. R, Baghel Us
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引用次数: 0
Concept, Manufacturing and Characterization of Effervescent Tablets: A Review 泡腾片的概念、制备及表征综述
Pub Date : 1900-01-01 DOI: 10.51737/2766-5232.2021.010
Prajapati Bg, Mishra O
Effervescent tablets are easy to consume due to this they are getting popular over other oral dosage forms. Effervescent tablets get break when they are put in water or juice which causes tablet to dissolve and form a solution. USFDA redefined the definition to Effervescent tablet is a tablet intended to be dissolved or dispersed in water before administration. Effervescent tablets consists of acids/acid salt, carbonates and hydrogen carbonates, flavour, sweetener, etc. which release carbon dioxide when it is added to water. Following chemical reaction takes place in effervescent tablets [1]. C6H8O7 (aq) + 3NaHCO3 (aq) → Na3C6H5O7 (aq) + 4H2O + 3CO2 (g) ↑ Citric acid + Sodium bicarbonate → Sodium citrate + Water + Carbon dioxide The above reaction occurs due to presence of water, because water is one of the reaction product which accelerates the reaction, leading to difficulty in stopping the reaction. Due to this reason manufacturing and storage of effervescent product is planned by minimizing their contact with water [2,3].
泡腾片很容易食用,因此它们比其他口服剂型更受欢迎。泡腾片放在水或果汁中会破裂,导致片剂溶解并形成溶液。美国食品药品监督管理局重新定义泡腾片是指在给药前溶解或分散在水中的片剂。泡腾片由酸/酸盐、碳酸盐和碳酸盐、香精、甜味剂等组成,当加入水中时会释放出二氧化碳。泡腾片[1]中发生如下化学反应。C6H8O7 (aq) + 3NaHCO3 (aq)→Na3C6H5O7 (aq) + 4H2O + 3CO2 (g)↑柠檬酸+碳酸氢钠→柠檬酸钠+水+二氧化碳上述反应是由于水的存在而发生的,因为水是加速反应的反应产物之一,导致反应难以停止。由于这个原因,泡腾品的制造和储存是通过尽量减少它们与水的接触来规划的[2,3]。
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引用次数: 3
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SunText Review of Pharmaceutical Sciences
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