Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa3760
P. Mariscal Aguilar, L. Gómez Carrera, Ester Zamarrón de Lucas, C. Carpio Segura, María Hidalgo Sánchez, G. Bonilla Hernán, M. I. Torres Sánchez, M. Fernández-Velilla Peña, P. Díaz-Agero Álvarez, E. Villamañán Bueno, R. R. Regojo Zapata, C. Prados Sánchez, R. Álvarez-Sala Walther
{"title":"Association between severity of Idiopathic Pulmonary Fibrosis and air Pollution levels in Madrid","authors":"P. Mariscal Aguilar, L. Gómez Carrera, Ester Zamarrón de Lucas, C. Carpio Segura, María Hidalgo Sánchez, G. Bonilla Hernán, M. I. Torres Sánchez, M. Fernández-Velilla Peña, P. Díaz-Agero Álvarez, E. Villamañán Bueno, R. R. Regojo Zapata, C. Prados Sánchez, R. Álvarez-Sala Walther","doi":"10.1183/13993003.congress-2021.pa3760","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3760","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85418424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.oa4336
Ida Pesonen, Å. Johnsson, F. Johansson, P. Wollmer, E. Lindberg, A. Blomberg, K. Torén, C. Östgren, M. Sköld
{"title":"Late Breaking Abstract - Prevalence of interstitial lung abnormalities in a Swedish population-based sample","authors":"Ida Pesonen, Å. Johnsson, F. Johansson, P. Wollmer, E. Lindberg, A. Blomberg, K. Torén, C. Östgren, M. Sköld","doi":"10.1183/13993003.congress-2021.oa4336","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa4336","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74257237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-07DOI: 10.1183/13993003.congress-2020.1851
Y. Qiu, R. Zhao, B. Elpers, Yuexi Wang, L. Xie, Jackson Tang, A. Fischer
{"title":"Prevalence and Characteristics of Patients Receiving Antifibrotic Therapy for Idiopathic Pulmonary Fibrosis","authors":"Y. Qiu, R. Zhao, B. Elpers, Yuexi Wang, L. Xie, Jackson Tang, A. Fischer","doi":"10.1183/13993003.congress-2020.1851","DOIUrl":"https://doi.org/10.1183/13993003.congress-2020.1851","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84689171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-07DOI: 10.1183/13993003.congress-2020.3716
Hirotaka Nishikiori, H. Chiba, K. Hirota, Tomohiro Suzuki, S. Honda, N. Yama, Kimiyuki Ikeda, Yuki Mori, Yuichiro Asai, Naomi Koyama, K. Kuronuma, M. Hatakenaka, Hiroki Takahashi
{"title":"Development of an artificial intelligence software to detect interstitial pneumonias","authors":"Hirotaka Nishikiori, H. Chiba, K. Hirota, Tomohiro Suzuki, S. Honda, N. Yama, Kimiyuki Ikeda, Yuki Mori, Yuichiro Asai, Naomi Koyama, K. Kuronuma, M. Hatakenaka, Hiroki Takahashi","doi":"10.1183/13993003.congress-2020.3716","DOIUrl":"https://doi.org/10.1183/13993003.congress-2020.3716","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88620890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-07DOI: 10.1183/13993003.congress-2020.1801
I. M. D. Zabaleta, J. D. M. Díez, Virginia Parra Leon, Z. Ji, A. L. Andrés, V. H. Barrera, A. C. Lajas, L. P. Maestú, R. García
{"title":"Prevalence and Characteristics of Patients with Idiopathic Pulmonary Fibrosis Admitted for Pneumonia Acquired in the Community","authors":"I. M. D. Zabaleta, J. D. M. Díez, Virginia Parra Leon, Z. Ji, A. L. Andrés, V. H. Barrera, A. C. Lajas, L. P. Maestú, R. García","doi":"10.1183/13993003.congress-2020.1801","DOIUrl":"https://doi.org/10.1183/13993003.congress-2020.1801","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75383790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.1183/13993003.congress-2019.pa4702
H. Habibie, J. Burgess, M. Wisman, M. Jonker, M. Kool, M. Wijsenbeek, N. Kahn, M. Kreuter, B. Melgert
{"title":"Serum osteoprotegerin and fibulin-1 levels negatively correlate with DLCO in IPF","authors":"H. Habibie, J. Burgess, M. Wisman, M. Jonker, M. Kool, M. Wijsenbeek, N. Kahn, M. Kreuter, B. Melgert","doi":"10.1183/13993003.congress-2019.pa4702","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa4702","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82130287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa2253
T. Neri, L. Tavanti, Sara De Magistris, S. Lombardi, C. Romei, A. Palla, P. Paggiaro, A. Celi
{"title":"Endothelial cell-derived microparticles as potential biomarkers in chronic interstitial lung diseases","authors":"T. Neri, L. Tavanti, Sara De Magistris, S. Lombardi, C. Romei, A. Palla, P. Paggiaro, A. Celi","doi":"10.1183/13993003.congress-2019.pa2253","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa2253","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73919967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.rct1880
T. Maher, T. Corte, A. Fischer, M. Kreuter, D. Lederer, M. Molina-Molina, J. Axmann, K. Kirchgaessler, K. Samara, F. Gilberg, V. Cottin
Introduction: There are no approved therapies for patients with uILD, who may have irreversible ILD. We evaluated efficacy and safety of pirfenidone in patients with progressive fibrosing uILD. Methods: This was a double-blind, randomised, placebo-controlled Phase II trial (NCT03099187). The primary endpoint was predicted FVC change over 24 weeks measured by daily home spirometry; secondary endpoints included changes in FVC (measured at site visits), DLco and 6MWD. Safety was also assessed. Results: 253 patients were randomised and 251 were treated (n=127 pirfenidone; n=124 placebo). Analysis of the primary endpoint was impacted by high intra-individual variability in home spirometry values in both treatment groups, amplified in patients with short observation periods, which prevented application of the planned statistical model. Median (Q1, Q3) FVC change (home spirometry) over 24 weeks was –87.7 mL (–338.1, 148.6) and –157.1 mL (–370.9, 70.1) in pirfenidone and placebo groups, respectively (Table). FVC change measured at site visits considerably favoured pirfenidone over placebo; results for DLco and 6MWD generally trended towards pirfenidone (Table). AE reporting reflected the known safety profile of pirfenidone. Conclusions: The planned statistical model could not be applied to the primary endpoint data. Results of key secondary endpoints suggest patients with progressive fibrosing uILD benefit from pirfenidone.
{"title":"Late Breaking Abstract - Phase II trial of pirfenidone in patients with progressive fibrosing unclassifiable ILD (uILD)","authors":"T. Maher, T. Corte, A. Fischer, M. Kreuter, D. Lederer, M. Molina-Molina, J. Axmann, K. Kirchgaessler, K. Samara, F. Gilberg, V. Cottin","doi":"10.1183/13993003.congress-2019.rct1880","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.rct1880","url":null,"abstract":"Introduction: There are no approved therapies for patients with uILD, who may have irreversible ILD. We evaluated efficacy and safety of pirfenidone in patients with progressive fibrosing uILD. Methods: This was a double-blind, randomised, placebo-controlled Phase II trial (NCT03099187). The primary endpoint was predicted FVC change over 24 weeks measured by daily home spirometry; secondary endpoints included changes in FVC (measured at site visits), DLco and 6MWD. Safety was also assessed. Results: 253 patients were randomised and 251 were treated (n=127 pirfenidone; n=124 placebo). Analysis of the primary endpoint was impacted by high intra-individual variability in home spirometry values in both treatment groups, amplified in patients with short observation periods, which prevented application of the planned statistical model. Median (Q1, Q3) FVC change (home spirometry) over 24 weeks was –87.7 mL (–338.1, 148.6) and –157.1 mL (–370.9, 70.1) in pirfenidone and placebo groups, respectively (Table). FVC change measured at site visits considerably favoured pirfenidone over placebo; results for DLco and 6MWD generally trended towards pirfenidone (Table). AE reporting reflected the known safety profile of pirfenidone. Conclusions: The planned statistical model could not be applied to the primary endpoint data. Results of key secondary endpoints suggest patients with progressive fibrosing uILD benefit from pirfenidone.","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74037233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa1325
J. Song, G. Kim, S. Weigt, L. Pourzand, William Hsu, Yu Shi, Matthew S. Brown, J. Goldin
{"title":"Prediction of IPF Progression Using HRCT Imaging Patterns in Elderly Population","authors":"J. Song, G. Kim, S. Weigt, L. Pourzand, William Hsu, Yu Shi, Matthew S. Brown, J. Goldin","doi":"10.1183/13993003.congress-2019.pa1325","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1325","url":null,"abstract":"","PeriodicalId":13242,"journal":{"name":"Idiopathic interstitial pneumonias","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75251645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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