Y. Shah, Abhilasha Patidar, M. Meena, Manish Jain, A. Mittal, Manisha Balai
Introduction: Atopic dermatitis (AD) is one of the most common dermatoses in the pediatric population and pruritus is its leading symptom; however, the clinical aspect of pruritus has not been studied much. The aim of the study was to explore clinical aspect of pruritus in pediatric AD and to analyze correlation of intensity of pruritus to the severity of AD. Methods: A hospital-based cross-sectional study of 106 pediatric patients of AD, between the age group of 6 months and 16 years was conducted. Diagnosis was made using the UK Working Party's Diagnostic Criteria for AD. The severity of pruritus and sleep disturbances were assessed using the Numerical Rating Scale, and the severity of AD was assessed using SCORing of AD index. Results: Mean age at onset was 4.73 years and the mean duration of disease was 1.07 years. Pruritus was localized in 66.03%, intermittent in 89.7%, and continuous in 10.3%. Winter aggravation was observed in 36.8% and sleep disturbances were observed in 39.62%. “Pruritus intensity” was moderate or severe in 92% of patients and had significant correlation to the duration and severity of the disease, sleep disturbances, and coexistence of other atopic diseases. Conclusion: A pediatric patient with AD usually presents with localized or generalized, moderate or severe pruritus, and with sleep disturbances. Exacerbation of pruritus was the most common in winter and due to woolen garments and sweating. The intensity of pruritus was in direct proportion with the duration and severity of AD and coexistence of other atopic diseases.
{"title":"Clinical aspect of pruritus in pediatric atopic dermatitis: A study from Western India","authors":"Y. Shah, Abhilasha Patidar, M. Meena, Manish Jain, A. Mittal, Manisha Balai","doi":"10.4103/ijpd.ijpd_24_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_24_22","url":null,"abstract":"Introduction: Atopic dermatitis (AD) is one of the most common dermatoses in the pediatric population and pruritus is its leading symptom; however, the clinical aspect of pruritus has not been studied much. The aim of the study was to explore clinical aspect of pruritus in pediatric AD and to analyze correlation of intensity of pruritus to the severity of AD. Methods: A hospital-based cross-sectional study of 106 pediatric patients of AD, between the age group of 6 months and 16 years was conducted. Diagnosis was made using the UK Working Party's Diagnostic Criteria for AD. The severity of pruritus and sleep disturbances were assessed using the Numerical Rating Scale, and the severity of AD was assessed using SCORing of AD index. Results: Mean age at onset was 4.73 years and the mean duration of disease was 1.07 years. Pruritus was localized in 66.03%, intermittent in 89.7%, and continuous in 10.3%. Winter aggravation was observed in 36.8% and sleep disturbances were observed in 39.62%. “Pruritus intensity” was moderate or severe in 92% of patients and had significant correlation to the duration and severity of the disease, sleep disturbances, and coexistence of other atopic diseases. Conclusion: A pediatric patient with AD usually presents with localized or generalized, moderate or severe pruritus, and with sleep disturbances. Exacerbation of pruritus was the most common in winter and due to woolen garments and sweating. The intensity of pruritus was in direct proportion with the duration and severity of AD and coexistence of other atopic diseases.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"116 - 120"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49019022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azathioprine (AZA) is a widely used immunosuppressive which when not monitored cautiously can lead to life-threatening complications like myelotoxicity. In resource-limited countries, acute hair loss starting as early as 2 weeks after drug initiation can be used as a surrogate marker of impending AZA-induced myelotoxicity.
{"title":"Acute-onset Alopecia in a Child: A Surrogate Marker of Azathioprine-induced Myelotoxicity","authors":"V. Mendiratta, Akanksha Agarwal, Smita Singh","doi":"10.4103/ijpd.ijpd_70_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_70_22","url":null,"abstract":"Azathioprine (AZA) is a widely used immunosuppressive which when not monitored cautiously can lead to life-threatening complications like myelotoxicity. In resource-limited countries, acute hair loss starting as early as 2 weeks after drug initiation can be used as a surrogate marker of impending AZA-induced myelotoxicity.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"150 - 153"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49508456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Jethwa, Vishalakshi Viswanath, M. Dhakne, P. R. Joshi
Sturge–Weber syndrome (SWS) is an uncommon, nonhereditary developmental condition characterized by nevus flammeus and ocular and neurological manifestations. Childhood-onset systemic lupus erythematosus (cSLE) is a rare disease with a female preponderance and is associated with multiple complications and a poor prognosis. The coexistence of cSLE and SWS is uncommon and can be associated with an increased risk of thromboembolic and neuropsychiatric complications. Macrophage activation syndrome (MAS) is one of the fatal complications of cSLE and an early diagnosis based on clinical findings and laboratory parameters is vital. We report a rare and unique case of SWS with cSLE in an 11-year-old boy, which was complicated by MAS.
{"title":"Sturge–Weber syndrome in childhood lupus complicated by macrophage activation syndrome","authors":"M. Jethwa, Vishalakshi Viswanath, M. Dhakne, P. R. Joshi","doi":"10.4103/ijpd.ijpd_95_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_95_22","url":null,"abstract":"Sturge–Weber syndrome (SWS) is an uncommon, nonhereditary developmental condition characterized by nevus flammeus and ocular and neurological manifestations. Childhood-onset systemic lupus erythematosus (cSLE) is a rare disease with a female preponderance and is associated with multiple complications and a poor prognosis. The coexistence of cSLE and SWS is uncommon and can be associated with an increased risk of thromboembolic and neuropsychiatric complications. Macrophage activation syndrome (MAS) is one of the fatal complications of cSLE and an early diagnosis based on clinical findings and laboratory parameters is vital. We report a rare and unique case of SWS with cSLE in an 11-year-old boy, which was complicated by MAS.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"173 - 176"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42214856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Shreya, D. Asati, M. Maheshwari, Vineet Kumar Sahu, D. Joshi
{"title":"Langerhans cell histiocytosis masquerading as papular-purpuric gloves and socks syndrome - Unusual manifestation of an uncommon condition","authors":"K. Shreya, D. Asati, M. Maheshwari, Vineet Kumar Sahu, D. Joshi","doi":"10.4103/ijpd.ijpd_39_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_39_22","url":null,"abstract":"","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"199 - 201"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46167229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Universal acquired melanosis, also referred to as Carbon baby syndrome, is a rare cause of progressive generalized hyperpigmentation of skin and mucosa. We describe a case of a 2-year-old boy with diffuse darkening of skin and mucosa for 3 months of age. Histopathology revealed increased melanin in the basal and suprabasal layers of the epidermis.
{"title":"Carbon baby syndrome: An unusual cause of progressive generalized melanosis","authors":"Anisha P. Bindagi, S. Srinivas","doi":"10.4103/ijpd.ijpd_86_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_86_22","url":null,"abstract":"Universal acquired melanosis, also referred to as Carbon baby syndrome, is a rare cause of progressive generalized hyperpigmentation of skin and mucosa. We describe a case of a 2-year-old boy with diffuse darkening of skin and mucosa for 3 months of age. Histopathology revealed increased melanin in the basal and suprabasal layers of the epidermis.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"157 - 160"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45574808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sporotrichosis is a chronic subcutaneous mycosis caused by a fungus, Sporothrix schenckii complex. The first case in India was reported by Ghosh in 1932. The disease is prevalent primarily in the sub-Himalayan region, North-eastern states, and parts of Karnataka. Mostly seen in adults, it uncommonly presents in children over the face and limbs either as fixed cutaneous or lymphocutaneous form. Here, we present a case of 3-years-old boy hailing from Southern Tamil Nadu with multiple nodular lesions in linear fashion over the right upper limb. It was diagnosed as a case of lymphocutaneous sporotrichosis that developed following cut injury over the right index finger. We publish this case as it is rare to occur in this geographic location.
{"title":"Lymphocutaneous sporotrichosis","authors":"Vijayaragavan Kutty, Balasankar Soundaian, Balasubramanian Jeyaraman, Sathishkumar Manisekaran","doi":"10.4103/ijpd.ijpd_89_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_89_22","url":null,"abstract":"Sporotrichosis is a chronic subcutaneous mycosis caused by a fungus, Sporothrix schenckii complex. The first case in India was reported by Ghosh in 1932. The disease is prevalent primarily in the sub-Himalayan region, North-eastern states, and parts of Karnataka. Mostly seen in adults, it uncommonly presents in children over the face and limbs either as fixed cutaneous or lymphocutaneous form. Here, we present a case of 3-years-old boy hailing from Southern Tamil Nadu with multiple nodular lesions in linear fashion over the right upper limb. It was diagnosed as a case of lymphocutaneous sporotrichosis that developed following cut injury over the right index finger. We publish this case as it is rare to occur in this geographic location.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"161 - 163"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43246711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immunoglobulin A (IgA) vasculitis (Henoch–Schönlein purpura) is an immune-mediated small vessel vasculitis, in which edema of the nondependent areas of the body, including the face and scalp is a rare cutaneous finding, found mostly in children <2 years of age. We report a case of a 7-year-old girl presenting with unilateral eyelid angioedema as a manifestation of IgA vasculitis. Early diagnosis and treatment are necessary, as the risk of renal complications increases with the incidence of angioedema.
{"title":"Unilateral eyelid angioedema: An atypical manifestation in childhood IgA vasculitis","authors":"R. Deepashree, A. Shyam Prasad","doi":"10.4103/ijpd.ijpd_78_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_78_22","url":null,"abstract":"Immunoglobulin A (IgA) vasculitis (Henoch–Schönlein purpura) is an immune-mediated small vessel vasculitis, in which edema of the nondependent areas of the body, including the face and scalp is a rare cutaneous finding, found mostly in children <2 years of age. We report a case of a 7-year-old girl presenting with unilateral eyelid angioedema as a manifestation of IgA vasculitis. Early diagnosis and treatment are necessary, as the risk of renal complications increases with the incidence of angioedema.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"154 - 156"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42713469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shradha Gurudev, G. Pise, Naveen Manohar, Vinitha Sanagoudar, K. Rao, Malteshgauda N Patil
Introduction: Papulosquamous disorders in children differ from those in adults in terms of presentations, treatments, and prognosis. The aim of this study was to add to the existing data regarding the presentation of pediatric papulosquamous disorders and analyze the metabolic parameters in children with psoriasis. Materials and Methods: This observational study included 83 patients (age, 0–18 years) with clinically diagnosed papulosquamous disorders. Demographic data and detailed clinical history were collected followed by a detailed clinical examination. In children with psoriasis, we assessed the parameters of metabolic health, such as anthropometry and blood chemistry. The outcomes are expressed as percentages and proportions. Results: Papulosquamous disorders constituted 2.3% of all the pediatric dermatoses with a male-to-female ratio of 1.7:1. They were commonly noted in the age group of 7–12 years. Psoriasis vulgaris (26.5%) was the most common disease followed by lichen planus (19.2%), seborrheic dermatitis (16.8%), pityriasis rosea (13.2%), lichen striatus (12%), lichen nitidus (7.2%), pityriasis lichenoides chronica (3.6%), and pityriasis rubra pilaris (1.20%). None of the 22 patients with psoriasis fulfilled the criteria for metabolic syndrome. However, aberrant serum levels included elevated fasting glucose (n = 5, 22.7%), elevated fasting triglycerides (n = 3, 13.6%), and decreased high-density lipoproteins (n = 2, 9.1%). Anthropometric abnormalities were also not noted. Conclusions: Understanding the morphological and epidemiological features of pediatric papulosquamous disorders can aid in early diagnosis, treatment, and counseling the patients and parents, which can alleviate their anxiety and improve the psychological distress.
{"title":"Clinico-Epidemiological study of papulosquamous disorders in childhood at a tertiary care hospital in South India","authors":"Shradha Gurudev, G. Pise, Naveen Manohar, Vinitha Sanagoudar, K. Rao, Malteshgauda N Patil","doi":"10.4103/ijpd.ijpd_50_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_50_22","url":null,"abstract":"Introduction: Papulosquamous disorders in children differ from those in adults in terms of presentations, treatments, and prognosis. The aim of this study was to add to the existing data regarding the presentation of pediatric papulosquamous disorders and analyze the metabolic parameters in children with psoriasis. Materials and Methods: This observational study included 83 patients (age, 0–18 years) with clinically diagnosed papulosquamous disorders. Demographic data and detailed clinical history were collected followed by a detailed clinical examination. In children with psoriasis, we assessed the parameters of metabolic health, such as anthropometry and blood chemistry. The outcomes are expressed as percentages and proportions. Results: Papulosquamous disorders constituted 2.3% of all the pediatric dermatoses with a male-to-female ratio of 1.7:1. They were commonly noted in the age group of 7–12 years. Psoriasis vulgaris (26.5%) was the most common disease followed by lichen planus (19.2%), seborrheic dermatitis (16.8%), pityriasis rosea (13.2%), lichen striatus (12%), lichen nitidus (7.2%), pityriasis lichenoides chronica (3.6%), and pityriasis rubra pilaris (1.20%). None of the 22 patients with psoriasis fulfilled the criteria for metabolic syndrome. However, aberrant serum levels included elevated fasting glucose (n = 5, 22.7%), elevated fasting triglycerides (n = 3, 13.6%), and decreased high-density lipoproteins (n = 2, 9.1%). Anthropometric abnormalities were also not noted. Conclusions: Understanding the morphological and epidemiological features of pediatric papulosquamous disorders can aid in early diagnosis, treatment, and counseling the patients and parents, which can alleviate their anxiety and improve the psychological distress.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"121 - 128"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47098141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Verrucous hemangioma in a child","authors":"Piyush Kumar, C. Desai, P. Das","doi":"10.4103/ijpd.ijpd_83_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_83_22","url":null,"abstract":"","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"180 - 181"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46335183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolated nail lichen planus in an indian boy","authors":"Priya Kapoor, A. Brar, M. Batrani","doi":"10.4103/ijpd.ijpd_80_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_80_22","url":null,"abstract":"","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"24 1","pages":"177 - 179"},"PeriodicalIF":0.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41319326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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