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Maxillary Sinus and Surrounding Bone Anatomy With Cone Beam Computed Tomography After Multiple Teeth Loss: A Retrospective Multicenter Clinical Study. 多牙脱落后上颌窦及周围骨的锥形束ct解剖:一项回顾性多中心临床研究。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000862
Erhan Dursun, H Gencay Keceli, Anil Dolgun, Miguel Velasco-Torres, Mehmet Olculer, Reihaneh Ghoreishi, Khaled Sinjab, Rachel A Sinacola, Marius Kubilius, Melek Didem Tözüm, Pablo Galindo-Moreno, H Guney Yilmaz, Hom-Lay Wang, Gintaras Juodzbalys, Tolga F Tözüm

Purpose: The aim of this multicenter study was to examine the residual alveolar bone anatomy and sinus mucosa pattern at maxillary sinus regions in multiple teeth loss.

Materials and methods: This study was conducted with cone beam computed tomography images of 518 patients (267 females and 251 males) with multiple posterior maxillary teeth loss. Variables associated with sinus membrane (SM), sinus dimensions, ostium, septa, sinus neighborhood, alveolar bone height and ridge width, posterior superior alveolar artery, and adjacent roots were evaluated.

Results: No (58.2%) or flat (19.3%) thickening morphology was detected at most of the SMs. Membrane thickening and mucosal-like morphology was more prevalent for male patients (P = 0.005). The mean sinus width was relatively low (3.64 ± 3.33 mm) at the 5-mm level and showed an expected increase toward upper levels. Most of the sinus spaces were dimensionally average (39.5%) or wide (44.7%), and no effect of gender was observed in terms of sinus dimensions (P > 0.05).

Conclusion: Multiple teeth loss plays a role in creating an imaginary sinus anatomy constituted of a relatively narrow space compared with single-tooth loss cases, from 3.6-mm mean coronal width to 11.3 mm in the apical portion.

目的:本研究旨在探讨多牙脱落患者上颌窦区残牙槽骨解剖及窦黏膜形态。材料与方法:对518例(女性267例,男性251例)多颗上颌后牙缺失的患者进行锥形束计算机断层扫描。评估与窦膜(SM)、窦尺寸、口、间隔、窦邻域、牙槽骨高度和嵴宽度、牙槽后上动脉和邻根相关的变量。结果:绝大多数细胞无增厚(58.2%)或扁平增厚(19.3%)。男性患者以膜增厚和粘膜样形态多见(P = 0.005)。平均窦宽在5-mm水平相对较低(3.64±3.33 mm),并有望向更高水平增加。大多数窦腔尺寸为平均(39.5%)或宽(44.7%),性别对窦腔尺寸无影响(P > 0.05)。结论:与单牙缺失患者相比,多牙缺失患者形成了一个相对狭窄的虚拟鼻窦解剖结构,平均冠状宽度从3.6 mm增加到尖部11.3 mm。
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引用次数: 7
Reflection and Transition. 反思和转变。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000899
Kenneth W M Judy
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引用次数: 0
Influence of Implant Length and Associated Parameters Upon Biomechanical Forces in Finite Element Analyses: A Systematic Review. 有限元分析中种植体长度及相关参数对生物力学力的影响:系统综述。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000879
Lukas Hingsammer, Bernhard Pommer, Stefan Hunger, Rapahel Stehrer, Georg Watzek, Angel Insua

Purpose: The aim of this systematic review is to provide an overview of finite element analyses comparing standard and short dental implants concerning biomechanical properties and to detect the most relevant parameters affecting periimplant stress concentrations.

Material and methods: After screening the literature and assessment of studies, 36 studies were included in this review.

Results: Eighty-three percent of the studies state that short dental implants have to bear higher stress concentrations compared with standard length implants. At the same time, 44% of articles note that implant diameter can be considered a more effective design parameter than implant length to reduce stress concentrations and to avoid an overload of periimplant bone. Regardless of implant dimension, in all studies, the highest stress concentrations are found in the cortical section around the upper part of the implant.

Conclusions: Unaffected of bone quality, implant diameter is found to play a key role to minimize periimplant stress concentrations. Concerning stress reduction implant length gains increasing relevance with decreasing bone density. Furthermore, splinting of short implants constitute an appropriate tool to avoid crestal overloading.

目的:本系统综述的目的是提供比较标准和短牙种植体有关生物力学性能的有限元分析的概述,并检测影响种植周应力浓度的最相关参数。材料和方法:经过文献筛选和研究评价,本综述共纳入36项研究。结果:83%的研究表明,与标准长度种植体相比,短种植体必须承受更高的应力浓度。同时,44%的文章指出,种植体直径可以被认为是比种植体长度更有效的设计参数,以减少应力集中并避免种植体周围骨超载。无论种植体的尺寸如何,在所有的研究中,在种植体上部周围的皮质部分发现了最高的应力浓度。结论:种植体直径不受骨质量的影响,在减少种植体周围应力集中方面起着关键作用。关于应力降低,种植体长度与骨密度的降低越来越相关。此外,短种植体的夹板是避免牙冠超载的适当工具。
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引用次数: 14
Frequency Values and Their Relationship With the Diameter of Dental Implants. Prospective Study of 559 Implants. 频率值及其与种植体直径的关系。559个种植体的前瞻性研究。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000887
Juan Manuel Aragoneses, Ana Suárez, Vanessa Arlette Brugal, Margarita Gómez

Purpose: The purpose of this prospective study is to evaluate the relationship between implant diameter, and primary and secondary stability.

Materials and methods: Five hundred fifty-nine implants with diameters of 3.7, 4.0, and 4.3 mm and lengths of 10 and 11.5 mm were placed in 195 patients. The resonance frequency was measured during surgery and at 3, 6, and 12 months.

Results: Related average implant stability quotient (ISQ) values were 69.62 for 3.7-mm implants, 72.02 for 4.0-mm implants, and 69.67 for 4.3-mm implants. Values in men were greater than values in women. Values were greater for the mandible than for the maxilla. There are significant differences between 4.0-mm implants, and 3.7 anterior maxilla and 4.3 posterior maxilla.

Conclusions: There is no relationship between increased ISQ values and increased diameters. We observed a preference regarding sex, with men having significantly greater values for 3.7- and 4.3-mm diameters. The mandible obtained the greatest ISQ values, with significant differences for diameters 3.7 and 4.3 mm.

目的:本前瞻性研究的目的是评估种植体直径与初级和次级稳定性之间的关系。材料与方法:共植入559个种植体,直径分别为3.7、4.0和4.3 mm,长度分别为10和11.5 mm,共195例患者。在手术期间和3、6、12个月时测量共振频率。结果:3.7 mm种植体ISQ平均值为69.62,4.0 mm种植体ISQ平均值为72.02,4.3 mm种植体ISQ平均值为69.67。男性的价值观高于女性的价值观。下颌骨的数值大于上颌骨。4.0 mm种植体与3.7前颌和4.3后颌差异显著。结论:ISQ值的增加与直径的增加没有关系。我们观察到对性别的偏好,男性对3.7毫米和4.3毫米直径的值明显更高。下颌骨的ISQ值最大,直径为3.7 mm和4.3 mm时差异显著。
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引用次数: 6
Effects of Platelet-Derived Material (Platelet-Rich Fibrin) on Bone Regeneration. 血小板来源材料(富血小板纤维蛋白)对骨再生的影响。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000877
Jae-Seek You, Su-Gwan Kim, Ji-Su Oh, Jae-Sung Kim

Purpose: The purpose of this study was to evaluate the effects of the growth factor within platelet-rich fibrin (PRF) in proliferation and differentiation of osteoblast and to observe the effectiveness of PRF.

Materials and methods: The colorimetric MTT assay, cell live and dead assay, alkaline phosphatase staining and activity assay, alizarine red S, and von Kossa staining were performed. Finally, the alterations of biomarkers associated with bone formation were verified at the mRNA level by quantitative polymerase chain reaction (PCR) and quantitative real-time PCR. In in vivo study, 6 adult mongrel dogs were used. The defect was performed and divided into 3 groups: (1) defect left unfilled, (2) defect filled with only 0.25-g Bio-Oss, and (3) defect filled with 0.25-g Bio-Oss mixed with PRF.

Results: MTT and cell live and dead assay showed that PRF did not affect the cell viability in MG-63 cells. The alkaline phosphatase activity, calcification, and mineralization were gradually increased in the MG-63 cells treated with PRF. Furthermore, the mRNA levels of biomarker gene in the MG-63 cells treated with PRF were significantly higher than those of control. In in vivo study, both radiographical and histological evaluations showed that the new bone formations were significantly increased in the defecting bone region transplanted with Bio-Oss and PRF compared with Bio-Oss only at 2 weeks after transplantation.

Conclusion: PRF can promote the bone regeneration without any complications.

目的:探讨富血小板纤维蛋白(PRF)内生长因子对成骨细胞增殖分化的影响,并观察PRF的作用。材料和方法:比色MTT法、细胞活与死法、碱性磷酸酶染色及活性法、茜素红S法、von Kossa法。最后,通过定量聚合酶链反应(PCR)和实时定量PCR在mRNA水平上验证与骨形成相关的生物标志物的改变。在体内研究中,选用6只成年杂种狗。将缺损进行修复,分为3组:(1)缺损未填充,(2)缺损仅填充0.25 g Bio-Oss,(3)缺损填充0.25 g Bio-Oss与PRF混合。结果:MTT和细胞活死实验显示,PRF对MG-63细胞的细胞活力无影响。PRF对MG-63细胞碱性磷酸酶活性、钙化和矿化作用逐渐增强。此外,PRF处理MG-63细胞的生物标志物基因mRNA水平显著高于对照组。在体内研究中,x线和组织学评估显示,移植后2周,与Bio-Oss相比,Bio-Oss和PRF移植的缺损骨区域的新骨形成明显增加。结论:PRF能促进骨再生,无并发症。
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引用次数: 30
Compatibility of Nonoriginal Abutments With Implants: Evaluation of Microgap at the Implant-Abutment Interface, With Original and Nonoriginal Abutments. 非原基台与种植体的相容性:原基台与非原基台在种植体-基台界面微间隙的评估。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000885
Revathi Duraisamy, Chitra Shankar Krishnan, Hariharan Ramasubramanian, Jayakrishnakumar Sampathkumar, Saravanakumar Mariappan, Azhagarasan Navarasampatti Sivaprakasam

Purpose: The purpose of this study was to evaluate the fit of nonoriginal abutments to implants at the implant abutment junction.

Materials and methods: Twenty titanium implants from a single manufacturer were randomly divided into 2 groups of ten each. Ten titanium premachined original abutments (group I) and ten titanium premachined nonoriginal abutments (from different manufacturer-group II) were connected to the implants with the recommended manufacturer torque level and then embedded into autopolymerizing clear acrylic resin blocks. After overnight curing, these blocks were vertically sectioned using water jet sectioning machine and evaluated under scanning electron microscope following the sequential cleaning procedures. The microgap at the implant-abutment interface for all the samples was measured using pixel counting software and subjected to statistical analysis using nonparametric Mann-Whitney U test.

Results: The mean microgap at the implant-abutment interface at the external, middle, and internal points was 1.597, 1.399, and 1.831 µm, respectively, for group I and 2.395, 2.488, and 3.339 µm, respectively, for group II samples. Nonparametric Mann-Whitney U test showed statistically significant difference between 2 groups at the midpoint for the nonoriginal abutments compared with the original ones.

Conclusion: Within the limitations of the study, the mean microgap at the implant-abutment interface at the platform level at the external, middle, and internal points for both original abutments and nonoriginal abutments was found to be within clinically acceptable limits.

目的:本研究的目的是评估非原始基台与种植体在种植体基台交界处的配合程度。材料与方法:同一厂家生产的钛种植体20枚,随机分为2组,每组10枚。将10个钛预制原始基台(第一组)和10个钛预制非原始基台(来自不同制造商-第二组)以推荐的制造商扭矩水平连接到种植体上,然后嵌入自动聚合的透明丙烯酸树脂块中。隔夜固化后,使用水射流切割机垂直切片,并在扫描电镜下按照顺序清洗程序进行评估。使用像素计数软件测量所有样品种植-基牙界面的微间隙,并使用非参数Mann-Whitney U检验进行统计分析。结果:第一组种植体-基牙界面外、中、内点的平均微间隙分别为1.597、1.399、1.831µm,第二组为2.395、2.488、3.339µm。非参数Mann-Whitney U检验显示两组间非原基牙中点与原基牙中点差异有统计学意义。结论:在本研究的限制范围内,无论是原始基牙还是非原始基牙,种植体-基牙界面在平台水平的外、中、内点的平均微间隙均在临床可接受的范围内。
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引用次数: 449
Osseodensification in Implant Dentistry: A Critical Review of the Literature. 种植牙的骨致密化:文献综述。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000884
Ahmed A Elsayyad, Reham B Osman

Introduction: Osseodensification is a technique that aims at bone preservation and compaction either through nonsubtractive drilling or implants with a special thread design. This can increase quantity and density of periimplant bone. This review represents a summary and a critical appraisal of the studies regarding osseodensification in the literature.

Materials and methods: Three databases were searched: PubMed (MEDLINE), Cochrane Library, and Latin American and Caribbean center on health sciences information (LILACS). Studies were screened by title/abstract according to predetermined eligibility criteria. Full texts of 7 eligible articles were read among which 2 were excluded and 5 articles were included and underwent qualitative synthesis.

Discussion: Studies advocating osseodensification are sparse and mainly animal studies of low evidence level. High risk of bias and low correlation between used animal models and human bone were detected in most of the studies.

Conclusion: Although osseodensification seems to be a very promising technique, the findings are inconclusive and should be cautiously interpreted. Well-designed animal and human studies of longer follow-up periods are required before implementing such technique in regular daily practice.

骨致密化是一种旨在通过非减法钻孔或特殊螺纹设计的植入物来保存和压实骨骼的技术。这可以增加种植周骨的数量和密度。本综述对文献中有关骨化的研究进行了总结和批判性评价。材料和方法:检索三个数据库:PubMed (MEDLINE)、Cochrane图书馆和拉丁美洲和加勒比健康科学信息中心(LILACS)。根据预先确定的资格标准,通过标题/摘要筛选研究。阅读符合条件的7篇文章的全文,其中2篇被排除,5篇被纳入,并进行定性综合。讨论:提倡骨化的研究较少,且以动物研究为主,证据水平低。在大多数研究中发现,所使用的动物模型与人骨之间存在高偏倚风险和低相关性。结论:虽然骨密度化似乎是一种很有前途的技术,但研究结果是不确定的,应谨慎解释。在将这种技术应用于日常实践之前,需要进行设计良好的动物和人类长期随访研究。
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引用次数: 11
Efficacy of a Polyglycol Dimethacrylate-Based Adhesive in Sealing the Implant-Abutment Interface. 聚乙二醇二甲基丙烯酸酯基粘接剂在种植体-基台界面密封中的效果。
3区 医学 Q1 Dentistry Pub Date : 2019-06-01 DOI: 10.1097/ID.0000000000000882
Caroline Bosquê Keedi, André Duarte Azevedo Marques, Viviane Aparecida Arenas Rodrigues, Mario Julio Avila-Campos, Pedro Tortamano

Purpose: The purpose of this study was to assess the effectiveness of a polyglycol dimethacrylate-based adhesive in preventing bacterial leakage through implant-abutment interfaces (IAIs).

Materials and methods: After implant installation, the adhesive was applied in the experimental group (n = 10). None was applied in the control group (n = 10). Samples were collected from the inner walls of implants on days 0 and 90. The real-time polymerase chain reaction was used to detect bacterial DNA.

Results: All samples from the control group, versus 30% from the experimental group, harbored bacterial DNA on day 90.

Conclusions: This polyglycol dimethacrylate-based adhesive may be used to seal the IAI. Further studies are warranted to verify its effectiveness over longer time periods.

目的:本研究的目的是评估聚乙二醇二甲基丙烯酸酯基粘接剂在防止细菌通过种植体-基台界面(IAIs)渗漏的有效性。材料与方法:实验组(n = 10)种植体安装后,使用黏合剂。对照组(n = 10)未应用任何药物。于第0天和第90天从种植体内壁采集样品。采用实时聚合酶链反应检测细菌DNA。结果:在第90天,对照组的所有样本都含有细菌DNA,而实验组的30%含有细菌DNA。结论:该聚乙二醇二甲基丙烯酸酯基胶粘剂可用于IAI的密封。有必要进一步研究以验证其在较长时间内的有效性。
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引用次数: 1
Implant Surface Decontamination by Surgical Treatment of Periimplantitis: A Literature Review. 种植体周围炎手术治疗的种植体表面净化:文献综述。
3区 医学 Q1 Dentistry Pub Date : 2019-04-01 DOI: 10.1097/ID.0000000000000840
Ki-Tae Koo, Fouad Khoury, Philip Leander Keeve, Frank Schwarz, Ausra Ramanauskaite, Anton Sculean, Georgios Romanos

Introduction: The purpose of this review was to evaluate the available published clinical studies to understand the current data on the decontamination efficacy of various agents used in the treatment of periimplantitis and reosseointegration.

Materials and methods: An electronic PubMed literature search was conducted for studies published from 1998 until 2018. Literature on clinical studies was included in the review. Of the 189 studies retrieved from the literature search, 33 articles were selected for the review.

Discussion: The available studies reviewed had great heterogeneity to conclude a single treatment of choice for implant surface decontamination for the surgical treatment of periimplantitis.

Conclusions: Existent data do not favor any decontamination approaches and fail to show the influence of a particular decontamination protocol on surgical therapy. Further clinical investigations are needed to determine the superiority of a decontamination method if existing.

简介:本综述的目的是评估现有的已发表的临床研究,以了解用于治疗种植体周围炎和再骨整合的各种药物的去污效果的当前数据。材料和方法:对1998年至2018年发表的研究进行了PubMed电子文献检索。本综述纳入了临床研究方面的文献。从文献检索中检索到的189项研究中,选择了33篇文章进行综述。讨论:现有的研究回顾有很大的异质性,结论是种植体表面净化的单一治疗选择种植体周围炎的手术治疗。结论:现有资料不支持任何去污方法,也没有显示特定的去污方案对手术治疗的影响。需要进一步的临床研究来确定现有的去污方法的优越性。
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引用次数: 35
Treatment Planning for Periimplant Mucositis and Periimplantitis. 种植体周围黏膜炎和种植体周围炎的治疗方案。
3区 医学 Q1 Dentistry Pub Date : 2019-04-01 DOI: 10.1097/ID.0000000000000869
Ioannis Polyzois

Purpose: A literature search was performed in a number of health care databases for articles published until January 2018.

Discussion: A number of anatomical factors, risk indicators, possible aesthetic complications, and financial implications have to be taken into consideration before treatment commences. When diagnosed early, periimplant mucositis is a problem that can be easily managed as long as the patient is motivated and maintains good levels of oral hygiene. Periimplantitis is more difficult to treat and results can be unpredictable. Nonsurgical therapy has limited effectiveness on the treatment of periimplantitis, but it should always precede a surgical intervention. Clinically predictable surgical outcomes seem to rely mainly on the configuration of the bone defect, the position of the affected implant, and the patient's ability to perform good oral hygiene.

Conclusions: Thorough treatment planning of periimplant diseases is paramount for the success of the treatment that follows. Local and general factors as well as patients' expectations have to be considered before proceeding, but treatment planning should also allow for a degree of flexibility, which will accommodate the unknown parameters.

目的:对2018年1月前发表的一些卫生保健数据库进行文献检索。讨论:在开始治疗之前,必须考虑许多解剖学因素、危险指标、可能的美学并发症和经济影响。当早期诊断时,种植体周围粘膜炎是一个很容易控制的问题,只要患者有动力并保持良好的口腔卫生水平。种植体周围炎更难治疗,结果难以预测。非手术治疗对种植体周围炎的治疗效果有限,但应始终先于手术干预。临床上可预测的手术结果似乎主要依赖于骨缺损的形态、受影响种植体的位置以及患者良好口腔卫生的能力。结论:种植体周围疾病的全面治疗计划对后续治疗的成功至关重要。在进行治疗之前,必须考虑局部和一般因素以及患者的期望,但治疗计划也应允许一定程度的灵活性,以适应未知的参数。
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引用次数: 6
期刊
Implant Dentistry
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