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Anaesthetic management of a patient with sickle cell disease: Case report and review of literature 镰状细胞病患者的麻醉治疗:病例报告及文献复习
Pub Date : 2023-09-15 DOI: 10.18231/j.ijca.2023.063
None Rajesh M C, None Syama G M, Anu Mary Thomas, None Jithin T N
Sickle cell anaemia is a haemoglobinopathy with an autosomal recessive inheritance. With the advent of advanced medical care, longevity of patients with sickle-cell disease has improved greatly. Our aim is to highlight the perioperative strategies to avoid complications due to the disease itself which can get exacerbated by moderate-high risk surgeries, hypoxia, dehydration, hypothermia, acidosis, vascular stasis and infection.
镰状细胞性贫血是一种常染色体隐性遗传的血红蛋白病。随着先进医疗技术的出现,镰状细胞病患者的寿命大大延长。我们的目的是强调围手术期策略,以避免因疾病本身引起的并发症,这些并发症可能因中高风险手术、缺氧、脱水、低体温、酸中毒、血管淤滞和感染而加剧。
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引用次数: 0
Successful Anaesthetic management of a diagnosed case of ITP with pregnancy undergoing lower section caeserian section ITP合并妊娠行下段剖宫产术1例麻醉治疗成功
Pub Date : 2023-09-15 DOI: 10.18231/j.ijca.2023.069
Mustafizur Rahman, Somalia Mukherjee, Madhulina Nag
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引用次数: 0
A randomized single-blinded comparative experimental study to test the influence of timing of intravenous fluid therapy on maternal hemodynamics during lower segmental caesarean section under spinal anaesthesia 一项随机单盲对比实验研究,探讨脊髓麻醉下剖宫产术中静脉输液时机对产妇血流动力学的影响
Pub Date : 2023-09-15 DOI: 10.18231/j.ijca.2023.049
Sinchu Mary Babu, Geo Navin Jude, R. Devaprasath
: Spinal anaesthesia-induced hypotension can be prevented by several techniques and methodologies, which is very important as the life of the mother and fetus is at risk. This study compared the efficacy of crystalloid administration 6 hours and half an hour before spinal anaesthesia on reducing hypotension.: After obtaining informed consent, 110 ASA 2 patients aged between 20 and 40 were scheduled for elective lower segmental caesarean section under spinal anaesthesia. Patients were randomly allocated into two groups. Group 1: Participants were kept nil per oral overnight, and Ringer's lactate was administered over half an hour before surgery. Group 2: participants were given ringer lactate. The amount was based upon the Holiday Segar formula (first 10 kg received 4ml/kg, 10-20 kg- 2ml/kg and remaining received 1 ml/kg) and given steadily over half an hour and 6 hours respectively in both groups. The incidence of hypotension and the need for rescue vasopressor in the two groups was recorded.: The two groups were statistically comparable in terms of age, height and weight. The incidence of Hypotension in Group 1 was 12.7%, and in Group 2 was 25%, which was statistically insignificant. Seven out of 55 patients in Group 1 had SBP<20% from baseline, whereas in Group 2, 14 patients out of 55 patients had SBP <20% from baseline, which was statistically insignificant. The incidence of ephedrine usage was statistically insignificant in both groups.: This study's results showed no statistically significant difference in preventing hypotension whether the fluids were given as 6 hours or half an hour before surgery. Therefore, to deliver preload of fluid, it is unnecessary to delay surgery.
脊髓麻醉引起的低血压可以通过几种技术和方法预防,这是非常重要的,因为母亲和胎儿的生命处于危险之中。本研究比较了脊髓麻醉前6小时和半小时晶体给药降低低血压的效果。在获得知情同意后,选择110例年龄在20 ~ 40岁的ASA 2型患者在脊髓麻醉下行选择性下节段剖宫产术。患者被随机分为两组。第一组:参与者每晚口服零剂量,在手术前半小时给予乳酸林格氏盐。第二组:给予乳酸林格酯。剂量根据Holiday Segar公式(前10 kg为4ml/kg, 10-20 kg- 2ml/kg,其余为1ml /kg),两组分别在半小时和6小时内稳定给予。记录两组患者低血压的发生率和救助性升压药物的使用情况。两组在年龄、身高和体重方面具有统计学上的可比性。第1组低血压发生率为12.7%,第2组为25%,差异无统计学意义。1组55例患者中有7例收缩压比基线值<20%,而2组55例患者中有14例收缩压比基线值<20%,差异无统计学意义。两组患者使用麻黄素的发生率均无统计学意义。本研究结果显示,术前6小时或半小时补液在预防低血压方面无统计学差异。因此,为了提供预负荷的液体,没有必要延迟手术。
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引用次数: 0
Anaesthetic challenges in surgical enucleation of pancreatic insulinoma 胰腺胰岛素瘤手术摘除麻醉的挑战
Pub Date : 2023-09-15 DOI: 10.18231/j.ijca.2023.061
P. Deb, Jabed Ahmed, P. Bhattacharyya
Insulinoma is a very rare tumour occurring in 1-4 persons per million per year. It is a functional endocrine tumour of the pancreas characterized by repeated attacks of hypoglycaemia presenting as adrenergic or neuroglycopenic symptoms. Surgical management of insulinoma is the mainstay of treatment which can be done by either laparoscopic or open approach. There is occurrence of rapid and wide fluctuations of blood glucose levels in the intraoperative as well as perioperative period. Intraoperative hypoglycaemia is critical due to masking of symptoms by the effect of anaesthesia and if not detected and treated promptly may lead to permanent neurological insult. We here-in describe the challenges of anaesthetic management in a case of functional pancreatic insulinoma undergoing open surgical enucleation with the help of intraoperative ultrasonography.
胰岛素瘤是一种非常罕见的肿瘤,每年每百万人中发生1-4人。它是胰腺的一种功能性内分泌肿瘤,以反复发作的低血糖为特征,表现为肾上腺素能性或神经性低糖症状。手术治疗是胰岛素瘤的主要治疗方法,可通过腹腔镜或开放方法进行。术中及围术期血糖水平出现快速、大幅度波动。术中低血糖是至关重要的,因为麻醉的作用掩盖了症状,如果不及时发现和治疗,可能导致永久性的神经损伤。我们在这里描述的挑战麻醉管理的情况下,功能性胰腺胰岛素瘤接受开放手术摘除术中超声的帮助。
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引用次数: 0
A randomized comparison of the performance of Airtraq videolaryngoscope versus Macintosh laryngoscope in simulated rapid sequence induction of anaesthesia Airtraq视频喉镜与Macintosh喉镜在模拟快速序列诱导麻醉中的随机比较
Pub Date : 2023-09-15 DOI: 10.18231/j.ijca.2023.057
Sapna Jain, G. Chilkoti, Vibhor Gupta, Ashok Kumar Saxena, Varun Seth, Prakriti Maurya
Application of cricoid pressure during rapid sequence induction (RSI) of anaesthesia leads to difficult airway. No channeled videolaryngoscope (VL) has been compared with the Macintosh laryngoscope for facilitating intubation in RSI. Thus, we compared Airtraq® VL with Macintosh laryngoscope for simulated RSI in patients scheduled for elective surgeries.Following approval from Institutional Ethics Committee-Human Research, this randomized study was conducted. Patients of either sex, aged 18-65yr, ASA grade I/II, scheduled for elective surgeries under GA were included. 'Group DL' underwent direct laryngoscopy (DL) using Macintosh laryngoscope and Group VL with Airtraq® videolaryngoscope. Time taken for intubation, Cormack-Lehane (CL) grade of laryngeal view, number of intubation attempts, and haemodynamic parameters were noted. Student t-test and chi square test were used for statistical analysis.A total of 140 patients with 70 in each group were included. The mean time taken for intubation was significantly higher in VL group (84.70 ± 28.05s) than DL group (23.90 ± 6.67s). The optimal laryngeal view (i.e. CL grade I or II) was significantly improved in VL group than DL group i.e. 97% vs 94%. In group DL, 99% (n=69) were intubated in first attempt; whereas 60% (n=42) in Group VL (p<0.001). Hemodynamics was better in group VL.Airtraq® VL is better than conventional Macintosh laryngoscope for endotracheal intubation during RSI in terms of optimal glottic view, ease of intubation and haemodynamics. On the contrary, the “time taken to intubation” and the first attempt intubation rate were higher with Airtraq® VL.
在快速序列诱导(RSI)麻醉过程中应用环状压力导致气道困难。无通道视频喉镜(VL)与Macintosh喉镜在促进RSI插管方面进行了比较。因此,我们比较了Airtraq®VL和Macintosh喉镜在计划择期手术的患者中模拟RSI的效果。经机构伦理委员会-人类研究批准后,进行了这项随机研究。患者不分性别,年龄18-65岁,ASA分级I/II,在GA下计划择期手术。DL组使用Macintosh喉镜进行直接喉镜检查(DL), VL组使用Airtraq®视频喉镜。记录插管时间、喉镜Cormack-Lehane (CL)分级、插管次数和血流动力学参数。采用学生t检验和卡方检验进行统计分析。共纳入140例患者,每组70例。VL组插管平均时间(84.70±28.05s)明显高于DL组(23.90±6.67s)。VL组的喉部最佳视点(即CL等级I或II)比DL组明显改善,分别为97%和94%。DL组99% (n=69)首次插管;而VL组为60% (n=42) (p<0.001)。VL组血流动力学较好。Airtraq®VL在最佳声门视野、插管便性和血流动力学方面优于传统Macintosh喉镜用于RSI期间的气管插管。相反,Airtraq®VL的“插管时间”和首次尝试插管率更高。
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引用次数: 0
Anaesthetic management of pregnant patients with severe dengue fever for emergency caesarean section - A case series and review 重症登革热孕妇急诊剖宫产的麻醉处理——病例系列与回顾
Pub Date : 2023-09-15 DOI: 10.18231/j.ijca.2023.059
Ranajit Chatterjee, Nandita Joshi, Lalit Gupta
: Dengue, a mosquito-borne viral infection, can lead to severe complications like dengue shock syndrome and severe thrombocytopenia. Pregnant patients with dengue present unique anaesthetic challenges. In this case series, we present the anaesthetic management of four pregnant patients with dengue who required emergency caesarean delivery.: All patients had severe thrombocytopenia and required platelet transfusions. Two patients developed respiratory distress and pulmonary edema in the perioperative period. One patient had severe liver function abnormalities along with thrombocytopenia, complicating the diagnosis. All patients received intensive care unit (ICU) management. None of the neonates tested positive for dengue.: The pathophysiological changes of pregnancy and dengue infection complicate the anaesthetic management of critically ill dengue patients. Thrombocytopenia and abnormal immune response lead to acute vascular permeability, plasma leakage, circulatory insufficiency, and polyserositis. Abnormal liver function tests and thrombocytopenia must be differentiated from HELLP syndrome. Over-transfusion of fluids due to shock can lead to pulmonary edema.: Pregnant patients with dengue fever pose a high risk of maternal and foetal mortality and morbidity. Successful anaesthetic management requires judicious transfusion of blood products and fluids based on the disease's complications and stage of illness. General anaesthesia is safe in these patients.
登革热是一种蚊媒病毒感染,可导致登革热休克综合征和严重血小板减少症等严重并发症。怀孕的登革热患者目前独特的麻醉挑战。在这个病例系列中,我们介绍了四个需要紧急剖腹产的登革热孕妇的麻醉管理。所有患者均有严重的血小板减少症,需要输血小板。2例患者围手术期出现呼吸窘迫和肺水肿。一名患者有严重的肝功能异常和血小板减少症,使诊断复杂化。所有患者均接受重症监护病房(ICU)管理。没有新生儿登革热检测呈阳性。妊娠和登革热感染的病理生理变化使重症登革热患者的麻醉管理复杂化。血小板减少和异常免疫反应导致急性血管通透性,血浆渗漏,循环功能不全和多浆液炎。肝功能异常和血小板减少症必须与HELLP综合征鉴别。因休克而过量输血可导致肺水肿。:患有登革热的孕妇对孕产妇和胎儿的死亡率和发病率具有很高的风险。成功的麻醉管理需要根据疾病的并发症和疾病阶段明智地输注血液制品和液体。对这些病人进行全身麻醉是安全的。
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引用次数: 0
A retrospective evaluation of characterization, clinical course and anaesthesia management of emergency trauma surgical patients during first wave of COVID-19 pandemic at a tertiary care center in India 回顾性评价印度一家三级医疗中心第一波COVID-19大流行期间急诊创伤手术患者的特征、临床过程和麻醉管理
Pub Date : 2023-06-15 DOI: 10.18231/j.ijca.2023.035
Parin Lalwani, B. Gupta, T. Goyal, Subodh Kumar
: The COVID-19 pandemic resulted in nationwide lockdown followed by phased unlock to break the chain of transmission of the SARS-CoV-2 virus in India. Management of emergency trauma patients has been particularly challenging for anaesthesiologists in order to treat these high risk group of patients and preventing cross infection to healthy patients as well as health care personnel. : It is a single centre retrospective observational cohort study conducted at tertiary care hospital in North India in the patients who underwent emergency trauma surgeries during 31 March 2020-31 May 2020(Lockdown) and compared with data from 1 June 2020-31 July 2020(Unlock). To compare the effect of lockdown and unlock during first wave of Covid-19 pandemic on the volume of emergency trauma surgical patients operated within 24 hours of admission.: To evaluate the difference between the two periods of lockdown and unlock a) in the mortality rates b) covid status c) the length of hospital stay d) the mechanism of injury e)severity of injury f)proportion of aerosol generating procedures (AGP) utilized and g)demographics of the patients. Our anaesthesia experience of managing the patients differently in the pandemic, identify areas for improvement, particularly in terms of minimising exposure and optimising resource usage in the management of such emergency patients in the event of a future healthcare crisis is also discussed. Over the 2 periods of lockdown and unlock there was no statistical difference in number, age or sex distribution of the patients presenting for emergency trauma surgery. Number of covid positive patients were slightly higher during unlock but it was statistically insignificant (p=0.07) and the number of patients died during unlock was also higher during unlock as compared to lockdown but statistically insignificant(p=0.3). The median injury severity score and length of stay was also not statistically significant between two periods. Road traffic accidents were most common type of injury in both the groups, self-inflicted injury occurred in 5 patients during lockdown and zero during unlock, none of these showed a significant difference (p > 0.06). General anaesthesia was the most common anaesthesia technique used in both the periods.Emergency trauma surgeries will continue to occur even in different phases of pandemics, anaesthesiologists should plan and prepare appropriately to provide anaesthesia and emergency care to these patients and prevent cross infection in healthy patients and health care workers.
COVID-19大流行导致全国范围内的封锁,随后分阶段解锁,以打破SARS-CoV-2病毒在印度的传播链。急诊创伤患者的管理对麻醉师来说尤其具有挑战性,以治疗这些高危患者群体并防止健康患者和卫生保健人员的交叉感染。这是一项在印度北部三级医院进行的单中心回顾性观察队列研究,研究对象是2020年3月31日至2020年5月31日(封锁)期间接受紧急创伤手术的患者,并与2020年6月1日至2020年7月31日(解锁)的数据进行比较。比较第一波新冠肺炎大流行期间封锁和解锁对入院24小时内急诊创伤外科患者数量的影响。评估两个封锁和解锁期间的差异a)死亡率b) covid状态c)住院时间d)损伤机制e)损伤严重程度f)使用的气溶胶产生程序(AGP)比例和g)患者人口统计学。还讨论了我们在大流行中以不同方式管理患者的麻醉经验,确定了需要改进的领域,特别是在未来发生医疗危机时,在管理此类急诊患者时尽量减少暴露和优化资源使用方面。在封锁和解锁的2个期间,急诊创伤手术患者的人数、年龄和性别分布没有统计学差异。解锁期间,新冠病毒阳性患者人数略高于封锁期间,但差异无统计学意义(p=0.07);解锁期间,患者死亡人数也高于封锁期间,但差异无统计学意义(p=0.3)。中位损伤严重程度评分和住院时间在两期之间也无统计学意义。道路交通事故是两组中最常见的伤害类型,自我伤害在封锁期间发生5例,在解锁期间发生0例,均无显著差异(p > 0.06)。在这两个时期,全身麻醉是最常用的麻醉技术。即使在流行病的不同阶段,紧急创伤手术也会继续发生,麻醉师应适当规划和准备,为这些患者提供麻醉和紧急护理,并防止健康患者和卫生保健工作者之间的交叉感染。
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引用次数: 0
Guillain – Barre syndrome with no known etiology: Rule out scrub typhus 病因不明的格林-巴利综合征:排除恙虫病
Pub Date : 2023-06-15 DOI: 10.18231/j.ijca.2023.046
D. Singla, D. Daunaria, Tiajem Jamir
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引用次数: 0
Rule of ‘2’ for lower extremity blocks 下肢阻塞的“2”规则
Pub Date : 2023-06-15 DOI: 10.18231/j.ijca.2023.041
Tuhin Mistry, Rinku Prajapati, Chetana V Bhalerao, Kartik Sonawane
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引用次数: 0
Receptive music therapy as an intraoperative aid for neuro-monitoring during growth rod surgery in a 5-year-old girl with severe congenital scoliosis: A case report 5岁女童重度先天性脊柱侧凸生长棒手术中接受性音乐治疗术中辅助神经监测一例
Pub Date : 2023-06-15 DOI: 10.18231/j.ijca.2023.038
Farah Husain, S. Wadhawan, T. Suri, S. Kumari, Ashika Joney
Neuromonitoring with sensory and motor evoked potentials is an essential tool during spinal correction surgeries to prevent any unforeseen cord injury intraoperatively and neurological deficit in the post-operative period. The muscle contraction and twitches resulting from cortical stimulation with a 200-250mA current are picked up by various subcutaneous/intradermal electrodes placed in the arms, hands, and legs creating a real-time assessment of any spinal cord injury caused by spinal implants or corrective maneuvers. During the neuromonitoring phase most anesthetic drugs such as volatile agents, neuromuscular blockers, and propofol may cause an interference with the electrode signals and therefore cannot be used. This could lead to significant risk of intraoperative awareness. Cases of intraoperative awareness have led to medical negligence and such incidents are the cause for 2% of the legal claims against anesthetists while patients with intraoperative awareness experience describe it as the worst thing they have ever suffered from. We therefore decided to use receptive music therapy, a novel aid in reducing chances of awareness during neuromonitoring.
在脊柱矫正手术中,感觉和运动诱发电位神经监测是防止术中意外脊髓损伤和术后神经功能缺损的重要工具。通过放置在手臂、手和腿上的各种皮下/皮内电极,通过200-250mA电流刺激皮质产生的肌肉收缩和抽搐,从而实时评估由脊柱植入物或矫正操作引起的任何脊髓损伤。在神经监测阶段,大多数麻醉药物,如挥发性药物、神经肌肉阻滞剂和异丙酚,可能对电极信号造成干扰,因此不能使用。这可能导致术中意识不清的重大风险。术中意识的案例导致了医疗疏忽,这类事件是2%针对麻醉师的法律索赔的原因,而有术中意识经历的患者将其描述为他们所经历过的最糟糕的事情。因此,我们决定使用接受性音乐疗法,这是一种在神经监测期间减少意识机会的新方法。
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引用次数: 0
期刊
Indian Journal of Clinical Anaesthesia
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