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Intraperitoneal local anesthetic instillation as a method to attenuate pneumoperitoneum induced hemodynamic response during laparoscopic surgeries: A randomized placebo controlled study 在腹腔镜手术中,腹腔内局部麻醉剂灌注可减轻腹腔积气引起的血流动力学反应:随机安慰剂对照研究
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.013
Murali Krishna Dommeti, Bharat Chandra Reddy, Rabbani Tappa, Gopinath Ramchandran, Venu Polapally
Laparoscopy is associated with significant hemodynamic changes due to pneumoperitoneum creation. We sought to study the effectiveness of intraperitoneal local anesthetic instillation in attenuating pneumoperitoneum-mediated hemodynamic response in patients undergoing laparoscopic cholecystectomy. This randomized study was conducted after approval from the institutional ethics committee, and 100 patients were randomly assigned to either group R (40 mL of 0.2% Ropivacaine intraperitoneally) or group N (40 mL of 0.9% normal saline intraperitoneally). Data analysis was performed using SPSS version 23. Independent Samples T test was used to compare hemodynamic variables between groups at regular intervals. Statistical significance was set less than 0.05.: Heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial blood pressure were significantly lower in Group R than in Group N at 15,30, 45,60,75, and 90 min (P<0.05).: Intra peritoneal instillation of 0.2% Ropivacaine in laparoscopic cholecystectomy attenuates intra operative hemodynamic changes associated with pneumoperitoneum.
腹腔镜手术与腹腔积气导致的显著血流动力学变化有关。我们试图研究腹腔镜胆囊切除术患者腹腔内局部麻醉剂灌注对减轻腹腔积气介导的血流动力学反应的有效性。这项随机研究是在获得机构伦理委员会批准后进行的,100 名患者被随机分配到 R 组(腹腔注射 40 毫升 0.2% 罗哌卡因)或 N 组(腹腔注射 40 毫升 0.9% 生理盐水)。数据分析采用 SPSS 23 版本。采用独立样本 T 检验比较各组间定期的血液动力学变量。在 15、30、45、60、75 和 90 分钟时,R 组的心率、收缩压、舒张压和平均动脉血压均显著低于 N 组(P<0.05):腹腔镜胆囊切除术中腹腔内灌注0.2%罗哌卡因可减轻与腹腔积气相关的术中血流动力学变化。
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引用次数: 0
A comparative study between 0.5% Ropivacaine with clonidine versus 0.5% Ropivacaine with dexmedetomidine in ultra sound guided supraclavicular brachial plexus block 在超声引导下锁骨上臂丛阻滞中 0.5% 罗哌卡因与氯尼替丁和 0.5% 罗哌卡因与右美托咪定的比较研究
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.004
Abhishek M. S., Nagaraju T. R
Adjuvants in blockade of the brachial plexus can lengthen patient care and hasten the ambulation with stable hemodynamics. Brachial plexus block has possible complications like local anaesthetic systemic toxicity, pneumothorax, nerve injury etc. which can be overcome by use of ultrasound guidance with adjuvants like dexmedetomidine and clonidine for postoperative analgesia. Ropivacaine has higher motor to sensory differentiation and lesser cardiotoxicity.A prospective blinded study comprising of 90 subjects posted for elective upper extremity surgeries. To compare the onset, duration of sensory and motor blockade and analgesia of 0.5% ropivacaine with clonidine 1mg.kg- and 0.5% ropivacaine with dexmedetomidine 1mg.kg-. Ninety patients aged 18 – 60yrs were chosen and randomly allocated into two groups of 45 participants. 20mL of 0.5% Ropivacaine and dexmedetomidine 1mg.kg-was administered to Group A and Group B received Ropivacaine and clonidine 1mg.kg-. In Group A, 73.3% of the subjects showed onset of sensory block of 8 minutes while it was 10 minutes in 26.7% of the subjects. In Group B, 44.4% of the patients showed onset of sensory block of 8 minutes, and 26.7% of the patients showed onset of sensory block of 10 min. Statistically, subjects in Group A showed decrease in onset of block and a higher mean duration of sensory and motor block in contrast to Group B. Addition of dexmedetomidine to 0.5% ropivacaine in supraclavicular brachial plexus block decreased the time of onset of sensory and motor block and extended the period of analgesia.
在阻断臂丛神经时使用辅助剂可延长对患者的护理时间,并在血液动力学稳定的情况下加速患者下床活动。臂丛神经阻滞可能会出现一些并发症,如局麻药全身毒性、气胸、神经损伤等,这些并发症可以通过使用超声引导和右美托咪定、氯尼丁等辅助药物进行术后镇痛来解决。罗哌卡因的运动与感觉分化程度较高,心脏毒性较小。这项前瞻性盲法研究由 90 名接受上肢择期手术的受试者组成。比较 0.5% 罗哌卡因与氯尼替丁 1 毫克/千克(kg-)和 0.5% 罗哌卡因与右美托咪定 1 毫克/千克(kg-)的起效时间、感觉和运动阻滞持续时间以及镇痛效果。我们选择了 90 名年龄在 18 - 60 岁之间的患者,将他们随机分配到两组,每组 45 人。A 组注射 20 毫升 0.5% 罗哌卡因和 1 毫克.千克右美托咪定,B 组注射罗哌卡因和 1 毫克.千克氯尼替丁。在 A 组中,73.3% 的受试者在 8 分钟内出现感觉阻滞,26.7% 的受试者在 10 分钟内出现感觉阻滞。在 B 组中,44.4%的患者在 8 分钟内出现感觉阻滞,26.7%的患者在 10 分钟内出现感觉阻滞。在锁骨上臂丛神经阻滞术中,在 0.5% 罗哌卡因中加入右美托咪定可缩短感觉和运动阻滞的开始时间,并延长镇痛时间。
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引用次数: 0
Anaesthetic management of a case of non-cirrhotic portal hypertension with severe thrombocytopenia for elective cesarean section 对一例非肝硬化门脉高压伴严重血小板减少的择期剖宫产手术的麻醉管理
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.021
A. Pushparani, Rajesh Priyadharshini, Urkavalan Karthika
Pregnancy with non-cirrhotic portal hypertension usually presents with portal hypertension due to Physiological hemodynamic changes associated with pregnancy, thereby putting the mother at risk of potentially dangerous complications like variceal bleeding and splenic aneurysmal rupture. Management of such cases requires a multidisciplinary approach involving obstetricians, gastroenterologist and, anesthesiologist Here through the case report of a 36-year-old primigravida with Non Cirrhotic portal hypertension with at 37 weeks gestational age in labor. We intend to focus upon different aspects of anesthetic management of pregnancy with portal hypertension and its complications.
妊娠合并非肝硬化性门脉高压症通常会因妊娠引起的生理血流动力学变化而导致门脉高压,从而使孕妇面临潜在危险并发症的风险,如静脉曲张出血和脾动脉瘤破裂。此类病例的处理需要产科医生、消化科医生和麻醉科医生等多学科参与。我们将重点讨论门脉高压症孕妇的麻醉管理及其并发症的各个方面。
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引用次数: 0
The impact of ultrasound- guided neuraxial blockade on anaesthetic outcomes in morbidly obese parturients: A case report 超声引导神经阻滞对病态肥胖产妇麻醉效果的影响:病例报告
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.020
Charu Sharma, Jyotsna Bhargava, R. Tiwari, Ritu Sharma
Obesity being a global epidemic is increasing in parturients nowadays, leading to super morbid obese parturient undergoing caesarean section. Caesarean section in morbidly obese poses many anaesthetic challenges under general anaesthesia a well as neuraxial anaesthesia. We report a case of super-super obese parturient with body mass index (BMI) of 63kg/m who underwent elective caesarean section under combined spinal epidural anaesthesia with ultrasound guidance successfully. We aim to highlight the anaesthetic considerations and implications associated with such patients.
肥胖症是一种全球性流行病,如今在产妇中的发病率越来越高,导致超级病态肥胖产妇接受剖腹产手术。在全身麻醉和神经轴麻醉下,病态肥胖者的剖腹产手术带来了许多麻醉难题。我们报告了一例体重指数(BMI)为 63kg/m 的超级肥胖产妇,她在超声引导下,在脊髓硬膜外联合麻醉下成功接受了择期剖腹产手术。我们旨在强调与此类患者相关的麻醉注意事项和影响。
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引用次数: 0
Comparison of post-operative analgesia with caudal Ropivacaine and Levobupivacaine in pediatric patients undergoing infraumbilical surgery under general anaesthesia 全身麻醉下接受脐下手术的小儿患者术后使用尾部罗哌卡因和左旋布比卡因镇痛的比较
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.005
U. Hariharan, Shashi Kumar Gupta, V. Nagpal, S. Wasnik
Post-operative pain relief following pediatric abdominal surgery is of paramount consideration and caudal block is still a popular, easy as well as safe analgesic technique for effective analgesia in children. With the advent of newer local anaesthetics, there has been a renewed interest in pediatric caudal blocks after lower abdominal surgeries following general anaesthesia. The aim of our study was to compare the efficacy and duration of postoperative analgesia using caudal Ropivacaine and Levobupivacaine in pediatric patients undergoing infraumbilical surgery under general anaesthesia.: The study was conducted on sixty, ASA grade 1, pediatric patients of age 2 to 6 years, of either sex, posted for elective infraumbilical surgery under general anaesthesia. They were randomly divided in two groups of 30 patients each. Group 1: - (n = 30) received caudal block with injection Ropivacaine, 0.25%, 1ml/kg. Group 2: - (n = 30) received caudal block with injection Levobupivacaine, 0.25%, 1ml/kg. Comparative, randomized, single blinded, observational study. : The demographic data was comparable in both the groups. Postoperatively, the quality of analgesia was assessed by the MOP (Modified Objective Pain Scale) score. Duration of postoperative analgesia was assessed by noting the time of giving rescue analgesia in the post-operative period. We also noted side effects, if any in both the groups. The quality of analgesia was found to be similar with both the drug groups (p value >0.05). The duration of analgesia was longer and statistically significant (p value = 0.0006) in the Ropivacaine group (8.43 ± 0.77 hours) as compared to the Levobupivacaine group (7.03 ± 2.03 hours). Statistically significant difference (P value = 0.026) was seen in the requirement rescue analgesia between Ropivacaine (3.33%) and Levobupivacaine (26.67%) groups. There were no major side effects in either of the groups, apart from a single patient out of 30 patients of Levobupivacaine group who had vomiting, compared with none in the Ropivacaine group.We conclude that caudal block with 0.25% Ropivacaine has a longer duration of action as compared to 0.25% Levobupivacaine in children undergoing infraumbilical surgery under general anaesthesia. Both Ropivacaine and Levobupivacaine, have similar quality of postoperative analgesia and side effect profile.
小儿腹部手术后的镇痛是最重要的考虑因素,而尾部阻滞仍然是小儿有效镇痛的常用、简便和安全的镇痛技术。随着新型局麻药的出现,小儿下腹部手术后全身麻醉后的尾部阻滞再次受到关注。我们的研究旨在比较使用罗哌卡因和左旋布比卡因对在全身麻醉下进行脐下手术的小儿患者进行术后镇痛的疗效和持续时间。 研究对象为 60 名年龄在 2 至 6 岁之间的 ASA 1 级小儿患者,性别不限,均在全身麻醉下接受脐下手术。他们被随机分为两组,每组 30 人。第一组:-(30 人)接受 0.25% 罗哌卡因注射液(1 毫升/公斤)的尾部阻滞。第 2 组:-(n = 30)接受注射左旋布比卡因(0.25%,1 毫升/千克)的尾阻滞。对比、随机、单盲、观察性研究:两组的人口统计学数据具有可比性。术后镇痛质量由 MOP(改良客观疼痛量表)评分评估。术后镇痛持续时间通过记录术后给予镇痛抢救的时间来评估。我们还记录了两组患者可能出现的副作用。结果发现,两组药物的镇痛质量相似(P 值大于 0.05)。罗哌卡因组的镇痛时间(8.43 ± 0.77 小时)比左布比卡因组(7.03 ± 2.03 小时)更长,差异有统计学意义(P 值 = 0.0006)。罗哌卡因组(3.33%)和左旋布比卡因组(26.67%)的镇痛抢救需要量有明显的统计学差异(P 值 = 0.026)。我们的结论是,与 0.25% 左旋布比卡因相比,在全身麻醉下接受脐下手术的儿童中,0.25% 罗哌卡因的尾部阻滞作用持续时间更长。罗哌卡因和左旋布比卡因的术后镇痛质量和副作用相似。
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引用次数: 0
A retrospective analysis of anesthetic techniques and their related perioperative complications in children undergoing cochlear implant surgeries – our preliminary experience at a tertiary care referral centre 对接受人工耳蜗植入手术儿童的麻醉技术及其相关围手术期并发症的回顾性分析--我们在一家三级医疗转诊中心的初步经验
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.003
Kriti Puri, R. Kundal, P. Varshney, Vidhi Chandra, M. Pandey, Sunil Kumar
: Cochlear implants serve as a favorable option for treatment of hearing loss in children. However, there is limited data regarding the type of anesthetic techniques used and its associated complications in such patients. Hence, the primary objective of this study was evaluation of postoperative nausea vomiting (PONV) with three different general anesthesia techniques in pediatric cochlear implant surgeries. The secondary objectives included assessment of intraoperative and postoperative complications: A retrospective analysis of all children less than 13 years, who underwent cochlear implant surgery at our hospital between December 2019 to February 2022 was performed. Appropriate data were noted. Nine patients each were classified into three groups (Group A, B and C) on the basis of anesthetic techniques used in our institution. Group A received inhalational agent for induction and maintenance, with no Non-Depolarizing Muscle Relaxant (NDMR), Group B patients received Total Intravenous Anesthesia with NDMR and Group C received intravenous induction and inhalational agent for maintenance with NDMR. Twenty-seven patients were included. There were no major intraoperative complications. PONV was noticed in two patients of Group A and one patient of Group C. One patient belonging to Group A developed laryngospasm and desaturation. Delayed Awakening was seen in one patient each of Group A, B and C. Overall, four complications were noted in patients of Group A, one in Group B and two in Group C. All complications were mild and were managed successfully.This preliminary study suggests that peri-operative anesthetic complications with all three anesthestic techniques were comparable and safe.
:人工耳蜗是治疗儿童听力损失的有利选择。然而,关于此类患者使用的麻醉技术类型及其相关并发症的数据却很有限。因此,本研究的首要目标是评估小儿人工耳蜗植入手术中三种不同全身麻醉技术的术后恶心呕吐(PONV)情况。次要目标包括评估术中和术后并发症:对2019年12月至2022年2月期间在我院接受人工耳蜗植入手术的所有13岁以下儿童进行回顾性分析。并记录了相关数据。根据本院使用的麻醉技术,将九名患者分为三组(A 组、B 组和 C 组)。A 组接受吸入剂诱导和维持,不使用非去极化肌肉松弛剂(NDMR);B 组患者接受全静脉麻醉,使用非去极化肌肉松弛剂(NDMR);C 组患者接受静脉诱导和吸入剂维持,使用非去极化肌肉松弛剂(NDMR)。共纳入 27 名患者。术中无重大并发症。A 组的两名患者和 C 组的一名患者出现了呕吐。A 组、B 组和 C 组各有一名患者出现苏醒延迟。总体而言,A 组有四例并发症,B 组有一例,C 组有两例。
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引用次数: 0
Anesthetic challenges in a patient of atypical Ludwig’s angina 非典型路德维希心绞痛患者的麻醉挑战
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.025
Shaista Jamil, Sonali Turki, Poonam Singh
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引用次数: 0
Successful management of malignant hyperthermia without dantrolene – A case report 不用丹曲林成功治疗恶性高热--病例报告
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.022
Jyoti Nara, Naveen Yalla
Malignant hyperthermia (MH) is a rare inherited genetic disorder implicated in a life-threatening catastrophic event under general anaesthesia. In India, the total number of reported cases are of the magnitude of single digit due to lack of reporting. The mortality of MH is dramatically decreased from 70-80% to less than 5%, due to an introduction of dantrolene sodium for treatment of MH, early detection of MH episode using capnography, and the introduction of diagnostic testing for MH.In India, there is enormous dependence on clinical grading scale rather than halothane caffeine contraction test due to the lack of availability of accredited testing facilities. In addition to this, the drug of choice dantrolene, is not readily available everywhere in India. The scarcity of quintessential monitoring techniques cannot be ignored in peripheral areas. Despite these limitations many reported cases have survived with vigilant monitoring, prompt diagnosis and aggressive supportive care.
恶性高热(MH)是一种罕见的遗传性疾病,在全身麻醉的情况下会导致危及生命的灾难性后果。在印度,由于缺乏报告,报告的病例总数仅为个位数。由于引入了丹曲林钠用于治疗 MH、使用毛细血管造影早期发现 MH 病例,以及引入了 MH 诊断测试,MH 的死亡率从 70-80% 大幅下降到 5%以下。此外,在印度,丹曲林(dantrolene)这种首选药物并不是随处都能买到。在边缘地区,基本监测技术的匮乏不容忽视。尽管存在这些局限性,但通过警惕性监测、及时诊断和积极的支持性治疗,许多报告的病例都得以存活。
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引用次数: 0
Indian Journal of Clinical Anaesthesia (IJCA): A journey form scholar to Scopus 印度临床麻醉杂志》(IJCA):从学者到 Scopus 的旅程
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.001
Lalit Gupta
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引用次数: 0
Comparative analysis of direct laryngoscopy and video laryngoscopy performance by medical students in simulated airway management scenarios 医科学生在模拟气道管理情景中直接喉镜检查和视频喉镜检查表现的比较分析
Pub Date : 2024-03-15 DOI: 10.18231/j.ijca.2024.010
Abna P K, Luqman Muhamed, Devdas Parapurath
This study aims to compare the effectiveness of video laryngoscopes and Macintosh laryngoscopes for intubation by novices in a mannequin model.This study was conducted at our institution- Karuna Medical College, Hospital. A total of 50 house surgeons were included in this study. All 50 participants intubated on the airway trainer using a video laryngoscope and a conventional method using a Macintosh laryngoscope. Group A: Video laryngoscopy, Group B: Conventional Laryngoscopy. The following parameters such as – time taken to visualize vocal cords, time taken to intubate, POGO scoring, ease of intubation, etc. were recorded.Video laryngoscope performed better in terms of time-related metrics, glottis visibility, and injury prevention to lip and teeth. Both devices had a similar ease of intubation and number of attempts. The results provide evidence supporting the advantages of the video laryngoscope in certain aspects of intubation procedures. The video laryngoscope had several benefits over the Macintosh laryngoscope, such as top quality visualization of airway structures and an easier intubation process for novices. The video laryngoscope provides superior visualization of the larynx, requires fewer external adjustments, and reduces the number of intubation attempts compared to direct laryngoscopy using a Macintosh blade.
本研究旨在比较视频喉镜和麦金塔喉镜在人体模型中为新手插管的效果。共有 50 名外科医生参与了这项研究。所有 50 名参与者都在气道训练器上使用视频喉镜和使用 Macintosh 喉镜的传统方法进行了插管。A组A组:视频喉镜,B组:传统喉镜。视频喉镜在时间相关指标、声门可见度以及防止唇齿损伤方面表现更好。两种设备的插管难易度和尝试次数相似。研究结果证明了视频喉镜在插管过程的某些方面具有优势。与 Macintosh 喉镜相比,视频喉镜有几个优点,如气道结构可视化质量高,插管过程对新手来说更容易。与使用 Macintosh 喉镜刀片进行直接喉镜检查相比,视频喉镜可提供更佳的喉部可视效果,所需的外部调整更少,并可减少插管次数。
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引用次数: 0
期刊
Indian Journal of Clinical Anaesthesia
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