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Psychological First Aid for People Affected by Skin Diseases. 皮肤病患者的心理急救。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2026-02-23 DOI: 10.4103/idoj.idoj_413_25
Aseem Mehra, Lalit K Singh, Tarun Narang

Abstract: Skin diseases, apart from the visible symptoms, can have devastating consequences like depression, anxiety, stigma, or suicidal ideation. These consequently can impact the daily activities and impair socio-occupational functionality. It is crucial to look for the available resources that address the needs of people with skin disease. Experts' consensus recommended that Psychological First Aid (PFA) has to be integrated into mental health guidelines and psychosocial support for skin diseases. Though there is a lack of strong evidence for the effectiveness of PFA, recent independent reviews highlighted the importance of providing the PFA to people who are in need. PFA is a "humane, supportive, and practical approach" focusing on reducing the emotional distress and to foster short and long-term adaptive functioning. PFA has key principles like Promoting Safety and Calm, Providing Practical Assistance, Active Listening, and Emotional Support and Respecting Dignity and Culture. PFA has three action principles: look, listen, and connect/link to provide care without hampering physical or psychological health. Hence, dermatologists and/or health nurses have to be trained to provide the PFA for people with basic needs.

摘要：除了可见的症状外，皮肤病还会带来毁灭性的后果，如抑郁、焦虑、耻辱或自杀念头。因此，这些会影响日常活动并损害社会职业功能。寻找满足皮肤病患者需求的现有资源至关重要。专家们一致建议，必须将心理急救（PFA）纳入皮肤病的心理健康指南和社会心理支持。虽然缺乏强有力的证据证明PFA的有效性，但最近的独立审查强调了向有需要的人提供PFA的重要性。PFA是一种“人道的、支持性的、实用的方法”，专注于减少情绪困扰，培养短期和长期的适应功能。PFA的主要原则包括促进安全和冷静、提供实际帮助、积极倾听、情感支持和尊重尊严和文化。PFA有三个行动原则：看，听，连接/链接提供护理而不妨碍身体或心理健康。因此，皮肤科医生和/或保健护士必须接受培训，以便为有基本需求的人提供PFA。
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引用次数: 0
The Unfolding of Familial CARD14- Associated Papulosquamous Eruption (CAPE) and a Brief Review. 家族CARD14-相关丘疹鳞状喷发（CAPE）的展开及简要综述。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2026-02-28 DOI: 10.4103/idoj.idoj_168_25
Swapnil Shah, Shibhani S Hegde, Arun Inamadar, Namrata V Dahe
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引用次数: 0
Winners of IDOJ 2025 Awards. IDOJ 2025获奖名单
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2026-02-28 DOI: 10.4103/idoj.idoj_win_2025
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引用次数: 0
Pulsatility of Telangiectasias on Dermoscopy: A Clue to the Diagnosis of Hereditary Hemorrhagic Telangiectasia. 皮肤镜下毛细血管扩张的脉搏：遗传性出血性毛细血管扩张的诊断线索。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2025-08-14 DOI: 10.4103/idoj.idoj_81_25
Arun Somasundaram, Deepti Singh, Avanija S Gajula, L Karthik, Sheetanshu Kumar
{"title":"Pulsatility of Telangiectasias on Dermoscopy: A Clue to the Diagnosis of Hereditary Hemorrhagic Telangiectasia.","authors":"Arun Somasundaram, Deepti Singh, Avanija S Gajula, L Karthik, Sheetanshu Kumar","doi":"10.4103/idoj.idoj_81_25","DOIUrl":"10.4103/idoj.idoj_81_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"235-236"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unexpected Stream: Exploring Forceful Urination Following Circumcision in a Child. 一种意想不到的流动：探索儿童割礼后的强排尿。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2025-07-23 DOI: 10.4103/idoj.idoj_1031_24
Riya Sukhija, Chakravarthi R Srinivas, Sejal Bajoria, Kriti Jain
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引用次数: 0
Hailey-Hailey Disease Complicated by Eczema Herpeticum: A Rare and Challenging Convergence of Two Acantholytic Disorders. 黑利-黑利病并发疱疹性湿疹：一种罕见且具有挑战性的两种棘皮溶解性疾病的汇合。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2025-09-19 DOI: 10.4103/idoj.idoj_1158_24
Priyansh Gupta, Priyanka Sangwan, Pavithra Ayyanar, Vishal Thakur
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引用次数: 0
Evaluation of Salivary Biomarkers, Cortisol and Total Antioxidant Capacity, and their Possible Role in Treatment Outcome in Patients with Symptomatic Oral Lichen Planus: A Pilot Study. 评估唾液生物标志物、皮质醇和总抗氧化能力及其在症状性口腔扁平苔藓患者治疗结果中的可能作用：一项初步研究
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2026-02-28 DOI: 10.4103/idoj.idoj_665_25
Admaja K Nair, Leela S Sreela, Thara Cherngod
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引用次数: 0
Rapid Identification of Drug-Resistant Strains of Mycobacterium leprae through qPCR High-Resolution Melt Analysis (HRMA): A High-Throughput and Effective Screening Method. qPCR高分辨率熔体分析（HRMA）快速鉴定麻风分枝杆菌耐药菌株：一种高通量、高效的筛选方法。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2026-02-27 DOI: 10.4103/idoj.idoj_188_25
Rahul Sharma, Itu Singh, Saurabh Gupta

Background: Rapid detection of drug-resistant Mycobacterium leprae is essential for effective treatment. Real-time polymerase chain reaction high-resolution melt (qPCR-HRM) analysis is a promising tool for this purpose. This study aimed to evaluate the reliability of qPCR-HRM for detecting drug-resistant strains of M. leprae in India.

Patients and methods: Skin biopsies or slit-skin scrapings from 48 leprosy patients; relapse ( n = 10), defaulters ( n = 2), reactional ( n = 17), and new cases ( n = 19), were analyzed. Drug resistance testing was conducted using qPCR-HRM and PCR followed by Sanger sequencing, following WHO guidelines.

Results: Drug resistance was detected in 9/48 (rifampicin), 11/48 (dapsone), and 5/48 (ofloxacin) by both methods. Dual resistance was seen in three patients: two with rifampicin and dapsone resistance, and one with rifampicin and ofloxacin resistance. Among new cases, mutations were detected in 10.5% (rifampicin) and 21.1% (dapsone); among reactional cases, in 23.5% (rifampicin), 11.8% (dapsone), 11.8% (ofloxacin), and 5.9% (rifampicin and ofloxacin); and among relapse cases, in 30% (rifampicin and ofloxacin), 50% (dapsone), and 20% (rifampicin and dapsone). No resistance was observed in defaulters. Sequencing confirmed mutation sites, and qPCR-HRM results were consistent with sequencing data.

Limitations: A limitation of the study is possible misclassification of samples that amplify beyond a threshold cycle (CT) of 30, which requires confirmation by PCR followed by DNA sequencing. Further, the inability of qPCR-HRM to determine exact mutation positions requires PCR/sequencing confirmation and a small sample size, which may limit generalizability.

Conclusion: qPCR-HRM is a reliable, rapid, and effective method for detecting drug resistance in leprosy. It provides results comparable to PCR and sequencing, making it suitable for large-scale screening in endemic regions.

背景：快速检测耐药麻风分枝杆菌对有效治疗至关重要。实时聚合酶链反应高分辨率熔体（qPCR-HRM）分析是一种很有前途的工具。本研究旨在评价qPCR-HRM检测印度麻风分枝杆菌耐药菌株的可靠性。患者与方法：48例麻风病患者皮肤活检或剥皮；分析复发（n = 10）、违约（n = 2）、反应（n = 17）和新发病例（n = 19）。按照世卫组织指南，采用qPCR-HRM和PCR进行耐药性检测，然后进行Sanger测序。结果：两种方法均可检出9/48（利福平）、11/48（氨苯砜）和5/48（氧氟沙星）的耐药情况。3例患者出现双重耐药：2例对利福平和氨苯砜耐药，1例对利福平和氧氟沙星耐药。在新发病例中，10.5%（利福平）和21.1%（氨苯砜）检测到突变；在反应性病例中，23.5%（利福平）、11.8%（氨苯砜）、11.8%（氧氟沙星）、5.9%（利福平和氧氟沙星）；复发率分别为30%（利福平和氧氟沙星）、50%（氨苯砜）和20%（利福平和氨苯砜）。在违约者中没有观察到任何抵抗。测序证实了突变位点，qPCR-HRM结果与测序数据一致。局限性：该研究的一个局限性是可能对扩增超过阈值周期（CT） 30的样本进行错误分类，这需要通过PCR和DNA测序进行确认。此外，qPCR-HRM无法确定确切的突变位置，需要PCR/测序确认和小样本量，这可能限制了通用性。结论：qPCR-HRM是一种可靠、快速、有效的麻风耐药检测方法。它提供了与PCR和测序相当的结果，使其适用于流行地区的大规模筛查。
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引用次数: 0
Pityriasis Versicolor Involving the Healed Herpes Zoster Scar - A Case of Wolf's Isotopic Response. 涉及愈合的带状疱疹瘢痕的花斑糠疹-狼的同位素反应一例。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2026-01-17 DOI: 10.4103/idoj.idoj_1209_24
Sonal Jain
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引用次数: 0
Chemotherapy-Induced Systemic Sclerosis-Like Changes. 化疗引起的系统性硬化症样改变。
IF 2 Q3 DERMATOLOGY
Indian Dermatology Online Journal
Pub Date : 2026-03-01 Epub Date: 2025-09-30 DOI: 10.4103/idoj.idoj_86_25
Priyansh Gupta, Arpita N Rout, Chandra S Sirka, Bhini Ameta
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引用次数: 0
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