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Survey of millets explored for the traditional food and medicine by the Rural Inhabitant of Salem District, Tamil Nadu-India 印度泰米尔纳德邦塞勒姆地区农村居民为传统食品和药物而探索的黍米调查
Pub Date : 2023-11-27 DOI: 10.26452/ijrls.v14i4.1501
K. Venketasan, Mohd Asif, Parwez Ahmed, Kabiruddin Ahmed, N. Zaheer Ahmed
This study investigated communication traits influencing awareness and adoption of recommended small millet cultivation practices among tribal millet farmers in the Salem District's Kolli hills and Salem forest divisions, Eastern Ghats of Tamil Nadu. Data, collected through personal interviews and informal discussions, aimed to address agrarian and nutritional challenges, emphasizing the potential of millets in dry lands for increased grain production. Millets, climate-resilient and nutritionally rich, offer benefits such as gluten-free composition, phytochemicals, and micronutrients crucial for immune function. Traditionally cultivated by Malayali tribes, millets exhibit medicinal and nutraceutical properties, contributing to the prevention of various health issues. The study highlights the rising interest in millets among scientists, technologists, and nutritionists, emphasizing their potential for value addition and processing to create ready-to-eat items. This not only benefits the masses but also provides income opportunities for rural and tribal farmers, promoting food security, employment, and revenue generation. Researchers focus on innovative approaches to enhance millet production, further underlining its significance in addressing current agricultural and nutritional challenges.Top of Form
本研究调查了影响泰米尔纳德邦东高止山脉塞勒姆地区科利山和塞勒姆森林分区部落黍农对推荐的小黍种植方法的认识和采用的交流特征。通过个人访谈和非正式讨论收集的数据旨在应对农业和营养方面的挑战,强调黍在旱地提高粮食产量的潜力。黍子具有气候适应能力,营养丰富,具有无麸质成分、植物化学物质和对免疫功能至关重要的微量营养素等优点。传统上由马拉雅部落种植的黍子具有药用和营养保健特性,有助于预防各种健康问题。这项研究强调了科学家、技术专家和营养学家对黍米日益增长的兴趣,强调了黍米的增值和加工潜力,以创造即食食品。这不仅能造福大众,还能为农村和部落农民提供创收机会,促进粮食安全、就业和创收。研究人员重点关注提高小米产量的创新方法,进一步强调小米在应对当前农业和营养挑战方面的重要性。
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引用次数: 0
Test 测试
Pub Date : 2023-03-22 DOI: 10.26452/ijrls.v13i1.1476
Sudeepthi Koppaka
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引用次数: 0
Test 测试
Pub Date : 2023-03-17 DOI: 10.26452/ijrls.v13i1.1477
Neelam
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引用次数: 0
Role of community pharmacy in public health 社区药房在公共卫生中的作用
Pub Date : 2020-11-16 DOI: 10.26452/ijrls.v10i3.1325
Senthil Kumar, P. MaheshkumarV, K. SenthilkumarS, D.Rajalingam
Currently, in every country, community pharmacists play an essential role as they take responsibility for access to healthcare for the medicine-related needs of patients. In India, however, only the provision of medicines remains the central movement of the group pharmacist. In the country, patient-oriented treatment is still rarely given by most community pharmacists. As domestic medicine development and national healthcare expenditure rise rapidly, the role of pharmacists in society and, with it, their management of medicines will change. The aim of this editorial is to examine the genesis of the private-owned Indian community pharmacy and to outline its education, training and prospects.
目前,在每个国家,社区药剂师都发挥着至关重要的作用,因为他们负责获得满足患者药物相关需求的医疗保健。然而,在印度,只有提供药物仍然是团体药剂师的中心运动。在这个国家,大多数社区药剂师仍然很少提供以病人为导向的治疗。随着我国医药事业的发展和国民医疗卫生支出的快速增长,药师在社会中的角色及其对药品的管理也将随之发生变化。这篇社论的目的是研究私营印度社区药房的起源,并概述其教育、培训和前景。
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引用次数: 0
A Review on Microsponge Drug Delivery System 微海绵给药系统研究进展
Pub Date : 2020-09-19 DOI: 10.26452/ijrls.v10i2.1280
Bharathi M, Mullaikodi O, Rajalingam D, Gnanasekar N, Kesavan M
A Microsponge (MS) is an extremely interconnected, permeable, polymeric structure that involves permeable microparticles trapping and discharging through the skin for a considerable time period. Drug delivery system (DDS) offer extended discharge with less degradation, improved physical stability along with better tolerance. The main intend of any DDS is to achieve the required amount of drug in plasma to produce the desired therapeutic and non-poisonous effect over a prolonged period of time. Specific methods for preparing MS were reviewed in this current investigation, and their pharmaceutical implementations were signed. MS have major DDS point of interest. It also improves stability, increased flexibility in formulation and increased elegance. In fact, numerous studies have reported that MS supplies are not allergic, mutagenic, and poisonous. MS creativity is used in products such as sunscreen, prescription, cosmetics, and OTC skin care. This inquiry primarily focuses on the different methods used to identify, plan and exploit MS.
微海绵(MS)是一种高度互联、可渗透的聚合物结构,可渗透的微粒在相当长的一段时间内通过皮肤捕获和放电。药物输送系统(DDS)提供了更大的放电,更少的降解,改善的物理稳定性以及更好的耐受性。任何DDS的主要目的是达到血浆中所需的药物量,以在较长时间内产生所需的治疗和无毒效果。本文综述了制备质谱的具体方法,并对其在药学上的应用进行了评述。MS有主要的DDS兴趣点。它还提高了稳定性,增加了配方的灵活性,增加了优雅性。事实上,大量的研究报告说,MS供应不会过敏,诱变和有毒。MS的创造力被用于防晒霜、处方、化妆品和非处方护肤品等产品。本研究主要集中在识别、计划和开发MS的不同方法上。
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引用次数: 1
A Shift from Cubicles to Couches 从小隔间到沙发的转变
Pub Date : 2020-08-26 DOI: 10.26452/ijrls.v10i2.1259
A. PadmavathiSivakumar, S. Sivasubramaniam
A cross-sectional, online survey was conducted in June 2020 to understand the perceptions of those who work from home (WFH). A questionnaire using Google Forms was sent across to employees of different age groups, job sectors and of various places. Queries included comfort, stress, change in work and family hours, online meetings, disrupting, most convenient and irritating factors of WFH, feeling of social isolation and missing of work-team activities. Of 72 respondents, 79% were men, 60% were above 40 years and two-thirds were in supervisory role. One in two are comfortable and relaxed with WFH. More than 60% reported increase in work hours. Family time has increased to all those who had working hours reduced. No-travel was the most convenient factor for one-third, while ‘increased work hours’ was the most irritating factor for 35%. Lack of proper infrastructure, privacy, family responsibilities and mindset were the main disruptions. Comfort-Stress factors did not vary significantly with age, gender, number of children and job level.  Change in work hours, change in family time, infrastructure, privacy, balance between work-home responsibilities in addition to missing team activities, social isolation were the factors of significance for comfort and stress. Given proper infrastructure, more privacy and regulated working hours, WFH can be more comfortable and stress-free. A study with larger sample size would provide comparable data across factors. Conducting organizational level surveys across its employees in WFH could reveal more insights to help decide on cost cutting, output quality and revised compensation structures.
2020年6月进行了一项横断面在线调查,以了解在家工作的人(WFH)的看法。使用谷歌表格向不同年龄段、不同行业和不同地区的员工发送了一份调查问卷。问题包括舒适度、压力、工作和家庭时间的变化、在线会议、WFH的干扰因素、最方便和最令人恼火的因素、社会孤立感和缺少工作团队活动。在72名受访者中,79%是男性,60%在40岁以上,三分之二担任管理职务。1 / 2的人使用WFH感到舒适和放松。超过60%的人表示工作时间增加了。对于那些工作时间减少的人来说,家庭时间增加了。三分之一的人认为不用出行是最方便的因素,而35%的人认为“工作时间增加”是最令人恼火的因素。缺乏适当的基础设施、隐私、家庭责任和心态是主要的干扰因素。不同年龄、性别、子女数量和工作水平对舒适-压力因素的影响不显著。工作时间的变化、家庭时间的变化、基础设施、隐私、工作与家庭责任之间的平衡以及缺少团队活动、社会孤立是影响舒适度和压力的重要因素。如果有适当的基础设施,更多的隐私和规范的工作时间,WFH可以更舒适和无压力。更大样本量的研究将提供跨因素的可比数据。对WFH的员工进行组织层面的调查可以揭示更多的见解,以帮助决定削减成本、提高产出质量和调整薪酬结构。
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引用次数: 0
Phytochemical and pharmacological review on Morinda citrifolia 桑葚的植物化学和药理研究进展
Pub Date : 2020-07-01 DOI: 10.26452/ijrls.v10i1.1192
R. Jubilee, M. Elakkiya, P. Ganapathy, M. Elakiya, Dinesh Kumar, A. Divya
Morinda citrifolia as the names suggests it is generally grown or harvested for fruits and the distribution of chemical constituents are also in other parts of the plants. The plant is native of South Asian countries and Western American lands in the pacific region. This plant has generally been used as a culinary vegetable and an edible fruit too and also considered as a natural immune booster and health enhancers. The plant was extracted to give most of the chemical constituents that possess anti-inflammatory, hypotensive, anti-tumour, antifungal, antiviral and anthelminthic activities. There had been significant uses that industries also employ as insecticidal agents and as chemical agents and catalyst. In this review, the details about the events, applications and studies that are performed on the plant were discussed.
桑葚顾名思义,它通常是为果实而种植或收获的,化学成分也分布在植物的其他部分。这种植物原产于南亚国家和太平洋地区的美国西部土地。这种植物通常被用作烹饪蔬菜和可食用的水果,也被认为是一种天然的免疫增强剂和健康增强剂。该植物被提取出具有抗炎、降血压、抗肿瘤、抗真菌、抗病毒和驱虫活性的大部分化学成分。它的重要用途还被工业用作杀虫剂、化学剂和催化剂。本文就该植物的事件、应用和研究进行了详细的讨论。
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引用次数: 0
Risk for death increasing with cardiovascular chronic gout patients associated with febuxostat 非布司他相关的心血管慢性痛风患者死亡风险增加
Pub Date : 2020-06-30 DOI: 10.26452/ijrls.v10i1.1189
K. Ramachandran, R. Yadav, Sumitra Devkota
Febuxostat used for the treatment of patients with arthritis littered with Hyperuricemia and is utilized in its Chronic Management. a number of the internal organ adverse effects have diode to the employment of febuxostat replaced with with allopurinol drug. Febuxostat, associate degree compound accelerator matter, achieves its therapeutic result by decreasing humour acid. At therapeutic concentrations it is not expected that Febuxostat will inhibit different enzymes which are involved in purine and pyrimidine synthesis and their metabolism. Metabolism of Febuxostat is done by conjugation via uridine diphosphate glucuronosyltransferase (UGT) enzymes and also by UGT1A1, UGT1A3, UGT1A9, and UGT2B7 and reaction via hemoprotein P450 (CYP) enzymes as well as CYP1A2, 2C8 and 2C9 and non-P450 enzymes. Febuxostat is eliminated primarily through each viscus and excretory organ pathways. Febuxostat could cause heart issues that may result in coronary failure, could cause issues within the blood vessels that visit your brain. this could conjointly result in stroke, urarthritis flare-ups and Liver injury. Some facet effects of febuxostat could occur that sometimes don't would like medical attention. We conclude from our review, vessel Death urarthritis patients with established vessel (CV) illness treated with febuxostat had a better rate of CV death compared to those treated with allopurinol drug in a very CV outcomes study.
非布司他用于治疗伴有高尿酸血症的关节炎患者,并用于其慢性管理。用别嘌呤醇类药物代替非布司他治疗有许多脏器不良反应。非布司他,副学士复合促进剂,通过降低幽默酸达到其治疗效果。在治疗浓度下,预计非布司他不会抑制参与嘌呤和嘧啶合成及其代谢的不同酶。非布司他的代谢是通过尿苷二磷酸葡萄糖醛基转移酶(UGT)酶和UGT1A1、UGT1A3、UGT1A9、UGT2B7缀合完成的,并通过血红蛋白P450 (CYP)酶以及CYP1A2、2C8、2C9和非P450酶进行反应。非布司他主要通过各个内脏和排泄器官途径排出。非布司他可能导致心脏问题,可能导致冠状动脉衰竭,可能导致访问大脑的血管出现问题。这可能会导致中风、尿关节炎发作和肝损伤。非布司他的一些方面的影响可能会发生,有时不需要就医。我们从我们的综述中得出结论,在一项非常CV结局的研究中,血管死亡性尿关节炎患者与非布司他治疗的血管(CV)疾病相比,使用别嘌呤醇治疗的心血管死亡率更高。
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引用次数: 0
Molecular modelling and evaluation of antihyperthyroid drug compound 抗甲状腺功能亢进药物化合物的分子模拟与评价
Pub Date : 2019-12-27 DOI: 10.26452/ijrls.v9i4.1350
A. Srikanth, T. Shivakmar, R. ShankarSheshu, S. Selvakumar
Drug targeting will play an essential function in drug discovery in the coming years, as the amount of structural records on protein targets keeps to rise. However, the conventional technique of drug discovery, primarily based upon random screening and systematic amendment of leads through medicinal chemistry strategies, will probably no longer to be deserted absolutely because it has doubtlessly vital advantages over shape-based strategies-specifically leads diagnosed in this way are unlikely to show a near resemblance to the herbal Ligand or substrate. They might also have gained in terms of patent novelty and selectivity. Such leads could then function the basis of structure-based totally, rational amendment programs, wherein their interactions with target receptors are described and improved molecules are designed. In the present study, an attempt is made to find suitable and better analogues of drugs used in the treatment of hyperthyroidism.
随着蛋白质靶点结构记录的数量不断增加,药物靶向将在未来几年的药物发现中发挥重要作用。然而,传统的药物发现技术,主要基于随机筛选和通过药物化学策略对先导物进行系统修改,可能不会再被完全抛弃,因为它无疑比基于形状的策略有重要的优势——特别是以这种方式诊断的先导物不太可能显示出与草药配体或底物接近的相似性。他们也可能在专利的新颖性和选择性方面获益。这样的导联可以在完全基于结构的基础上发挥作用,合理的修饰程序,其中它们与目标受体的相互作用被描述并设计改进的分子。在本研究中,试图寻找适合和更好的药物类似物用于治疗甲状腺机能亢进。
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引用次数: 0
Variations in the Antioxidant Profile of Aegle marmoles with Drying and Solvent of Extraction 风干和萃取溶剂对凝胶型海摩尔抗氧化特性的影响
Pub Date : 2019-10-28 DOI: 10.26452/ijrls.v9i3.1347
M. Ch, Y GaneshKumar, D Pranitha, D PhaneendraPavan
There are various processes in the crude drug processing which affects the quality of the drug in many ways. The quality of the crude drug is the determining factor that is responsible for the imports and exports of the drug to international markets. Drying is a significant step in those post-harvesting stages of the crude drug. This alone determines the microorganism contamination in the drug. Other post-harvesting methods that affect the final extract of the crude drug is the selection f solvent for extraction. The solvent selection is to be based on the parameters like the partition coefficient, the solubility of the chemical constituents. Aegle marmoles is well known for its antioxidant activity and other potential activities, and the exports of the drug were in more massive scale. To ensure the quality of the drug, the post-harvest technology of the drug was essential to determine the quality of the crude drugs. The leaves were dried in different methods and extracted with different solvents, and the investigations were done for the antioxidant activity. The results showed that the extract of the shade dried drug and the methanol solvent extracted drug showed a better phenol content and also better antioxidant activity.
在生药的加工过程中有各种各样的工序,这些工序在许多方面影响着药物的质量。生药的质量是决定药品进口和出口到国际市场的决定性因素。干燥是药材采收后阶段的重要步骤。这就决定了药物中微生物的污染程度。其他影响药材最终提取的采收后方法是提取溶剂的选择。溶剂的选择要根据分配系数、化学成分的溶解度等参数来确定。该药物以其抗氧化活性和其他潜在活性而闻名,其出口规模较大。为保证药材质量,药材采收后工艺是确定药材质量的关键。采用不同的干燥方法和不同的溶剂提取方法,对其抗氧化活性进行了研究。结果表明,遮荫干燥药物和甲醇溶剂提取药物的酚含量较高,抗氧化活性也较好。
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引用次数: 0
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International Journal of Review in Life Sciences
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