首页 > 最新文献

Indian Journal of Surgery最新文献

英文 中文
‘Mid-term Reflections of the President’—Charting Progress and Future Directions for the Association of Surgeons of India
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-19 DOI: 10.1007/s12262-024-04135-5
Probal Neogi
{"title":"‘Mid-term Reflections of the President’—Charting Progress and Future Directions for the Association of Surgeons of India","authors":"Probal Neogi","doi":"10.1007/s12262-024-04135-5","DOIUrl":"https://doi.org/10.1007/s12262-024-04135-5","url":null,"abstract":"","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142266441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bleeding Jejunal Diverticula: Always a Timely Reminder
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-16 DOI: 10.1007/s12262-024-04137-3
Pranesh Rambarran, Juhi Priyam Singh, Suman Mewa Kinoo, Bhugwan Singh

Bleeding jejunal diverticula is a rare cause of lower gastrointestinal bleeding. We describe a case of rectal bleeding secondary to jejunal diverticula disease and outline our experience of managing bleeding jejunal diverticula in current practice.

{"title":"Bleeding Jejunal Diverticula: Always a Timely Reminder","authors":"Pranesh Rambarran, Juhi Priyam Singh, Suman Mewa Kinoo, Bhugwan Singh","doi":"10.1007/s12262-024-04137-3","DOIUrl":"https://doi.org/10.1007/s12262-024-04137-3","url":null,"abstract":"<p>Bleeding jejunal diverticula is a rare cause of lower gastrointestinal bleeding. We describe a case of rectal bleeding secondary to jejunal diverticula disease and outline our experience of managing bleeding jejunal diverticula in current practice.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142266440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinico-Radiological Features of Acute and Chronic Superior Mesenteric Artery Occlusion (SMAO)
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-16 DOI: 10.1007/s12262-024-04149-z
Kulumani M. Sivasubramaniyan, Venkateswara Gomathi Shankar, Kramadhari Harshith, Krishnan Nagarajan, Mohan Amuthabharathi, Sekar Sabarish

Superior mesenteric artery occlusion (SMAO) can present as acute mesenteric ischemia (AMI) with bowel necrosis or as mesenteric vascular narrowing with collateral formation, resulting in chronic mesenteric ischemia (CMI). The diagnosis is often delayed due to a low clinical index of suspicion, leading to a high mortality rate. We aimed to characterize the clinical and radiological features of SMAO. This retrospective study included 39 patients with SMAO reported on CT for 3 years. We compared the clinical features from medical records with imaging and intraoperative findings. The CT features of vessel occlusion, status of collaterals, bowel changes, and other intra-abdominal findings apart from involvement of other vessels (celiac, renal, aortic, neck vessels) were analyzed. Out of 39 patients, 12 had acute SMAO, and the remaining 27 patients had chronic SMAO and were sub-classified into Takayasu (n = 13) and non-Takayasu (n = 14) sub-groups. The acute group had proximal and distal occlusions equally and bowel gangrene changes but without collaterals, whereas chronic group had mainly proximal stenosis/occlusion and no bowel changes with well-formed collaterals. Involvement of other abdominal and peripheral vessels was noted in the chronic group (both Takayasu and non-Takayasu) but less in acute group patients. Early surgery in the acute group was associated with a better prognosis and CT-detected bowel ischemia changes correlated well with intraoperative findings. Acute and chronic SMAO have distinct features in terms of level and type of occlusion, bowel ischemic changes and collaterals. Takayasu arteritis may be a subset of chronic SMAO with associated changes, which warrant further elucidation.

肠系膜上动脉闭塞(SMAO)可表现为急性肠系膜缺血(AMI)伴有肠坏死,也可表现为肠系膜血管狭窄伴有侧支形成,导致慢性肠系膜缺血(CMI)。由于临床怀疑指数较低,诊断往往被延误,从而导致较高的死亡率。我们的目的是描述 SMAO 的临床和放射学特征。这项回顾性研究纳入了 39 名在 3 年内通过 CT 报告的 SMAO 患者。我们将病历中的临床特征与影像学和术中发现进行了比较。我们分析了血管闭塞的 CT 特征、络脉状况、肠道变化以及除其他血管(腹腔、肾、主动脉、颈部血管)受累外的其他腹腔内发现。在 39 名患者中,12 人患有急性 SMAO,其余 27 人患有慢性 SMAO,并被分为高安亚组(13 人)和非高安亚组(14 人)。急性组的近端和远端闭塞程度相同,有肠道坏疽改变,但无袢,而慢性组主要是近端狭窄/闭塞,无肠道改变,袢形成良好。慢性组(包括高安市和非高安市)患者的其他腹部和外周血管均受累,而急性组患者则较少受累。急性组患者早期手术预后较好,CT 检测到的肠缺血变化与术中发现有很好的相关性。急性和慢性 SMAO 在闭塞程度和类型、肠缺血性改变和袢方面具有不同的特征。高安动脉炎可能是慢性 SMAO 的一个亚型,其相关变化值得进一步阐明。
{"title":"Clinico-Radiological Features of Acute and Chronic Superior Mesenteric Artery Occlusion (SMAO)","authors":"Kulumani M. Sivasubramaniyan, Venkateswara Gomathi Shankar, Kramadhari Harshith, Krishnan Nagarajan, Mohan Amuthabharathi, Sekar Sabarish","doi":"10.1007/s12262-024-04149-z","DOIUrl":"https://doi.org/10.1007/s12262-024-04149-z","url":null,"abstract":"<p>Superior mesenteric artery occlusion (SMAO) can present as acute mesenteric ischemia (AMI) with bowel necrosis or as mesenteric vascular narrowing with collateral formation, resulting in chronic mesenteric ischemia (CMI). The diagnosis is often delayed due to a low clinical index of suspicion, leading to a high mortality rate. We aimed to characterize the clinical and radiological features of SMAO. This retrospective study included 39 patients with SMAO reported on CT for 3 years. We compared the clinical features from medical records with imaging and intraoperative findings. The CT features of vessel occlusion, status of collaterals, bowel changes, and other intra-abdominal findings apart from involvement of other vessels (celiac, renal, aortic, neck vessels) were analyzed. Out of 39 patients, 12 had acute SMAO, and the remaining 27 patients had chronic SMAO and were sub-classified into Takayasu (<i>n</i> = 13) and non-Takayasu (<i>n</i> = 14) sub-groups. The acute group had proximal and distal occlusions equally and bowel gangrene changes but without collaterals, whereas chronic group had mainly proximal stenosis/occlusion and no bowel changes with well-formed collaterals. Involvement of other abdominal and peripheral vessels was noted in the chronic group (both Takayasu and non-Takayasu) but less in acute group patients. Early surgery in the acute group was associated with a better prognosis and CT-detected bowel ischemia changes correlated well with intraoperative findings. Acute and chronic SMAO have distinct features in terms of level and type of occlusion, bowel ischemic changes and collaterals. Takayasu arteritis may be a subset of chronic SMAO with associated changes, which warrant further elucidation.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142266411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilizing Hysteroscopic Mesh Resection for Presacral Mesh Infection Following Sacrocolpopexy 利用宫腔镜网片切除术治疗骶骨成形术后的骶前网片感染
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-16 DOI: 10.1007/s12262-024-04161-3
Zhenzhen Wu, Chunxiao He, Xudong Han, Bin Ma, Huiling Wang, Yaqin Zhao, Futang Ma, Fang Wang, Qing Liu

This study assessed the feasibility and efficacy of hysteroscopic mesh resection in managing presacral mesh infection following sacrocolpopexy. A retrospective analysis was conducted on three cases of presacral mesh infection treated with hysteroscopic total mesh resection between January 2020 and December 2021. The cases were classified and diagnosed using category-time-site (CTS) coding for complications, and perioperative indicators were evaluated. The mean age of the patients was 61.67 years (SD 4.44). Surgical time averaged 37.33 min (SD 5.11), with an intraoperative bleeding volume of 13.33 ml (SD 4.44). The hospitalization cost was 12,436.43 yuan (SD 2281.79), and the postoperative hospitalization duration was 6.25 days (SD 0.88). The preoperative frailty index was 0.18 in two out of three cases, indicating favorable surgical tolerance. There were no 30-day unplanned readmissions. At 3 months post-operation, the Patient Global Impression of Improvement (PGI-I) score was 100%, indicating good outcomes with a subjective cure rate of 100%. These findings indicate that hysteroscopic mesh resection could be a viable and effective treatment modality for presacral mesh infection following sacrocolpopexy.

{"title":"Utilizing Hysteroscopic Mesh Resection for Presacral Mesh Infection Following Sacrocolpopexy","authors":"Zhenzhen Wu, Chunxiao He, Xudong Han, Bin Ma, Huiling Wang, Yaqin Zhao, Futang Ma, Fang Wang, Qing Liu","doi":"10.1007/s12262-024-04161-3","DOIUrl":"https://doi.org/10.1007/s12262-024-04161-3","url":null,"abstract":"<p>This study assessed the feasibility and efficacy of hysteroscopic mesh resection in managing presacral mesh infection following sacrocolpopexy. A retrospective analysis was conducted on three cases of presacral mesh infection treated with hysteroscopic total mesh resection between January 2020 and December 2021. The cases were classified and diagnosed using category-time-site (CTS) coding for complications, and perioperative indicators were evaluated. The mean age of the patients was 61.67 years (SD 4.44). Surgical time averaged 37.33 min (SD 5.11), with an intraoperative bleeding volume of 13.33 ml (SD 4.44). The hospitalization cost was 12,436.43 yuan (SD 2281.79), and the postoperative hospitalization duration was 6.25 days (SD 0.88). The preoperative frailty index was 0.18 in two out of three cases, indicating favorable surgical tolerance. There were no 30-day unplanned readmissions. At 3 months post-operation, the Patient Global Impression of Improvement (PGI-I) score was 100%, indicating good outcomes with a subjective cure rate of 100%. These findings indicate that hysteroscopic mesh resection could be a viable and effective treatment modality for presacral mesh infection following sacrocolpopexy.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142266438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Execution of Ipsilateral Radical Tonsillectomy and Tongue Base Mucosal Wedge Biopsy with Trans Oral Robotic Surgery (TORS) in the Setting of Carcinoma Unknown Primary (CUP): Insights into Surgical Techniques and Instrumentation 在原发癌不明(CUP)的情况下使用经口腔机器人手术(TORS)实施同侧根治性扁桃体切除术和舌根部黏膜楔形活检:对手术技术和器械的见解
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-13 DOI: 10.1007/s12262-024-04154-2
Naresh Kumar Panda, Karthika Chettuvatti, Jaimanti B. Bakshi

Transoral robotic surgery (TORS) has transformed the management of oropharyngeal tumors with its precise and minimally invasive techniques. However, its role in identifying primary sites in carcinoma of unknown primary with secondary neck nodal metastasis remains understudied. Here, we present a case series of 18 patients who underwent ipsilateral radical tonsillectomy and tongue base mucosal wedge biopsy using transoral robotic surgery (TORS) at a tertiary care institute. This study offers a concise overview of the surgical steps and instrumentation employed in the procedure, focusing on patient positioning, robotic arm placement, optical dilation, tissue dissection, hemostasis, and closure. By elucidating the technical nuances of the surgical procedure, this study aims to promote the adoption of minimally invasive approaches in head and neck surgery, thereby advancing patient care.

经口机器人手术(TORS)以其精确的微创技术改变了口咽部肿瘤的治疗。然而,它在识别原发部位不明、继发颈部结节转移癌中的作用仍未得到充分研究。在此,我们介绍了在一家三级医疗机构使用经口机器人手术(TORS)进行同侧扁桃体根治术和舌根粘膜楔形活检的 18 例患者的病例系列。本研究简明扼要地概述了手术步骤和手术中使用的器械,重点介绍了患者定位、机器人手臂放置、光学扩张、组织剥离、止血和闭合。通过阐明手术过程中的技术细节,本研究旨在促进微创方法在头颈部手术中的应用,从而提高患者护理水平。
{"title":"Execution of Ipsilateral Radical Tonsillectomy and Tongue Base Mucosal Wedge Biopsy with Trans Oral Robotic Surgery (TORS) in the Setting of Carcinoma Unknown Primary (CUP): Insights into Surgical Techniques and Instrumentation","authors":"Naresh Kumar Panda, Karthika Chettuvatti, Jaimanti B. Bakshi","doi":"10.1007/s12262-024-04154-2","DOIUrl":"https://doi.org/10.1007/s12262-024-04154-2","url":null,"abstract":"<p>Transoral robotic surgery (TORS) has transformed the management of oropharyngeal tumors with its precise and minimally invasive techniques. However, its role in identifying primary sites in carcinoma of unknown primary with secondary neck nodal metastasis remains understudied. Here, we present a case series of 18 patients who underwent ipsilateral radical tonsillectomy and tongue base mucosal wedge biopsy using transoral robotic surgery (TORS) at a tertiary care institute. This study offers a concise overview of the surgical steps and instrumentation employed in the procedure, focusing on patient positioning, robotic arm placement, optical dilation, tissue dissection, hemostasis, and closure. By elucidating the technical nuances of the surgical procedure, this study aims to promote the adoption of minimally invasive approaches in head and neck surgery, thereby advancing patient care.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142178095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emphysematous Pyelonephritis on X-ray Abdomen X 射线腹部显示气肿性肾盂肾炎
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-13 DOI: 10.1007/s12262-024-04156-0
Himanshu Agrawal, Nitin Agarwal, Nikhil Gupta

A 70-year-old diabetic female presented to emergency with complaints of severe pain in right loin region, fever with chills, and burning micturition since last 1 week. X-ray abdomen was suggestive of emphysematous pyelonephritis which was confirmed by contrast CT abdomen. She recovered after percutaneous nephrostomy with broad spectrum antibiotic coverage.

一名 70 岁的女性糖尿病患者因右腰部剧烈疼痛、发热伴寒战、排尿灼热而急诊就诊。腹部 X 光片显示为气肿性肾盂肾炎,腹部对比 CT 证实了这一点。经皮肾造瘘术和广谱抗生素治疗后,她康复了。
{"title":"Emphysematous Pyelonephritis on X-ray Abdomen","authors":"Himanshu Agrawal, Nitin Agarwal, Nikhil Gupta","doi":"10.1007/s12262-024-04156-0","DOIUrl":"https://doi.org/10.1007/s12262-024-04156-0","url":null,"abstract":"<p>A 70-year-old diabetic female presented to emergency with complaints of severe pain in right loin region, fever with chills, and burning micturition since last 1 week. X-ray abdomen was suggestive of emphysematous pyelonephritis which was confirmed by contrast CT abdomen. She recovered after percutaneous nephrostomy with broad spectrum antibiotic coverage.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142178096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Indications for Enteric Stoma Creation in Emergency Laparotomy for Acute Abdomen: Insights from a Retrospective Descriptive Study
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-13 DOI: 10.1007/s12262-024-04162-2
Krishna Prakash, Saurav Manna, Dibakar Halder, Utpal De

The rise in stoma creation after emergency laparotomy has surged significantly in recent years, contrasting sharply with earlier practices of resection and anastomosis. Despite advances in management, which were expected to reduce this trend, it has instead escalated, imposing a burden on healthcare costs and impacting the quality of life for stoma patients. This study seeks to examine the factors influencing the necessity for enteric stomas during emergency laparotomies for acute abdominal conditions. This descriptive observational study was conducted in the Department of General Surgery at a Medical College & Hospital, from November 2022 to January 2024, analyzing data from March 2019 to March 2021. It included 70 patients aged 18 to 60 who underwent enteric stoma creation during emergency laparotomy. Data were collected retrospectively from medical records and analyzed using descriptive statistics. The study included 70 patients with an average age of 43.7 ± 14.4 years; 43 males and 27 females. The primary indications for stoma creation were obstructing colonic cancer (38.5%), non-traumatic small bowel perforation (14.2%), and sigmoid volvulus (11.4%). Ileostomies were predominant (58.5%), with double-barrel ileostomy being the most common (31.4%). Short-term complications occurred in 28.5% of patients, with surgical site infections being the most common (55%). The study highlights a paradoxical increase in enteric stoma creation despite advancements in surgical care. The findings underscore the need for further research into the factors influencing the decision to create a stoma, beyond immediate surgical considerations.

近年来,急诊开腹手术后造口术的数量大幅上升,与早期的切除和吻合术形成鲜明对比。尽管管理方面的进步有望减少这一趋势,但这一趋势反而有所上升,给医疗成本造成了负担,并影响了造口患者的生活质量。本研究旨在探讨影响急腹症紧急开腹手术中肠道造口必要性的因素。这项描述性观察研究于 2022 年 11 月至 2024 年 1 月在医学院附属医院普外科进行,分析了 2019 年 3 月至 2021 年 3 月的数据。研究纳入了 70 名年龄在 18 至 60 岁之间、在急诊开腹手术中接受肠造口手术的患者。数据通过病历回顾性收集,并使用描述性统计进行分析。研究包括 70 名患者,平均年龄(43.7 ± 14.4)岁,其中男性 43 名,女性 27 名。造口术的主要适应症是梗阻性结肠癌(38.5%)、非外伤性小肠穿孔(14.2%)和乙状结肠肿(11.4%)。回肠造口术占多数(58.5%),其中双管回肠造口术最常见(31.4%)。28.5%的患者出现短期并发症,其中手术部位感染最为常见(55%)。该研究强调,尽管外科护理取得了进步,但肠造口术却出现了反常的增长。研究结果强调,除了直接的手术考虑因素外,还需要进一步研究影响造口决定的因素。
{"title":"Indications for Enteric Stoma Creation in Emergency Laparotomy for Acute Abdomen: Insights from a Retrospective Descriptive Study","authors":"Krishna Prakash, Saurav Manna, Dibakar Halder, Utpal De","doi":"10.1007/s12262-024-04162-2","DOIUrl":"https://doi.org/10.1007/s12262-024-04162-2","url":null,"abstract":"<p>The rise in stoma creation after emergency laparotomy has surged significantly in recent years, contrasting sharply with earlier practices of resection and anastomosis. Despite advances in management, which were expected to reduce this trend, it has instead escalated, imposing a burden on healthcare costs and impacting the quality of life for stoma patients. This study seeks to examine the factors influencing the necessity for enteric stomas during emergency laparotomies for acute abdominal conditions. This descriptive observational study was conducted in the Department of General Surgery at a Medical College &amp; Hospital, from November 2022 to January 2024, analyzing data from March 2019 to March 2021. It included 70 patients aged 18 to 60 who underwent enteric stoma creation during emergency laparotomy. Data were collected retrospectively from medical records and analyzed using descriptive statistics. The study included 70 patients with an average age of 43.7 ± 14.4 years; 43 males and 27 females. The primary indications for stoma creation were obstructing colonic cancer (38.5%), non-traumatic small bowel perforation (14.2%), and sigmoid volvulus (11.4%). Ileostomies were predominant (58.5%), with double-barrel ileostomy being the most common (31.4%). Short-term complications occurred in 28.5% of patients, with surgical site infections being the most common (55%). The study highlights a paradoxical increase in enteric stoma creation despite advancements in surgical care. The findings underscore the need for further research into the factors influencing the decision to create a stoma, beyond immediate surgical considerations.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142266442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contribution of Nobel Laureate and Physicist Sir CV Raman in Oncosurgery 诺贝尔奖获得者、物理学家 CV 拉曼爵士对肿瘤外科的贡献
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-12 DOI: 10.1007/s12262-024-04158-y
Kaushik Bhattacharya, Sandeep Kumar, Santhosh John Abraham, Probal Neogi, Sanjay Kumar Jain, G Siddesh

Raman spectroscopy discovered by Nobel laureate Sir Chandrasekhara Venkata Raman from India in 1928 changed the history of Oncosurgery and gave a new direction and dimension to the diagnosis, management, screening, and treatment of cancer. The amalgamation of laser and artificial intelligence in spectroscopy made this invention of Raman an extremely useful non-invasive tool in cancer surgery and management. Apart from intraoperative guidance, early detection, and tumor classification, Raman spectroscopy was found to be useful in the assessment of residual disease, therapeutic monitoring of chemotherapy drugs and radiotherapy, biomarker invention, drug delivery monitoring, and cancer screening. While Raman spectroscopy shows great promise in cancer research and diagnosis, it is still a developing field, and further research is needed to fully understand its potential.

1928 年诺贝尔奖获得者、印度的钱德拉塞卡拉-文卡塔-拉曼爵士(Sir Chandrasekhara Venkata Raman)发现的拉曼光谱改变了肿瘤外科的历史,为癌症的诊断、管理、筛查和治疗提供了新的方向和维度。激光和人工智能在光谱学中的结合,使拉曼的这一发明成为癌症手术和管理中极为有用的非侵入性工具。除了术中引导、早期检测和肿瘤分类外,拉曼光谱还可用于评估残留疾病、化疗药物和放疗的治疗监测、生物标记物的发明、给药监测和癌症筛查。虽然拉曼光谱在癌症研究和诊断方面大有可为,但它仍然是一个发展中的领域,需要进一步研究才能充分了解其潜力。
{"title":"Contribution of Nobel Laureate and Physicist Sir CV Raman in Oncosurgery","authors":"Kaushik Bhattacharya, Sandeep Kumar, Santhosh John Abraham, Probal Neogi, Sanjay Kumar Jain, G Siddesh","doi":"10.1007/s12262-024-04158-y","DOIUrl":"https://doi.org/10.1007/s12262-024-04158-y","url":null,"abstract":"<p>Raman spectroscopy discovered by Nobel laureate Sir Chandrasekhara Venkata Raman from India in 1928 changed the history of Oncosurgery and gave a new direction and dimension to the diagnosis, management, screening, and treatment of cancer. The amalgamation of laser and artificial intelligence in spectroscopy made this invention of Raman an extremely useful non-invasive tool in cancer surgery and management. Apart from intraoperative guidance, early detection, and tumor classification, Raman spectroscopy was found to be useful in the assessment of residual disease, therapeutic monitoring of chemotherapy drugs and radiotherapy, biomarker invention, drug delivery monitoring, and cancer screening. While Raman spectroscopy shows great promise in cancer research and diagnosis, it is still a developing field, and further research is needed to fully understand its potential.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142178097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between Gastric Cancer and Vitamin D in Kashmiri Population: A 2 Year Case–Control Study at a Tertiary Care Hospital 克什米尔人口中胃癌与维生素 D 的关系:一家三级医院为期两年的病例对照研究
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-10 DOI: 10.1007/s12262-024-04152-4
Younis Mushtaq, Shariq Rashid Masoodi, Mubashir Shah, Ajaz Qadir

Introduction: The association between vitamin D level and gastric cancer has not been studied in our population despite the high prevalence of vitamin D deficiency and gastric cancer. Patients and Methods: This was a 26-month case series analysis study in which 59 patients with histologically confirmed gastric cancer and age and sex-matched 60 patients with suspicion of Helicobacter Pylori infection were taken as controls to find out any association between low 25 hydroxy vitamin D level and malignancy. Results: The mean age of the cases and controls was 57 SD (standard deviation)10 and 56 SD 9 years, respectively. The mean vitamin D levels in cases and controls were 20.15 ng/ml and 32.21 ng/ml, which was statistically significant (p < 0.0001). Only 3 (5%) controls showed vitamin D deficiency (< 20 ng/ml), compared to 30 (50.84%) cases, which was statistically significant (p < 0.001). The mean vitamin D levels in well differentiated, moderately differentiated and poorly differentiated adenocarcinoma were 26.10, 23.25 and 14.88 ng/ml, respectively, which was statistically significant (p < 0.001). Stage III gastric adenocarcinoma (50.8%) was the most common, followed by stage II (42.4%), stage I (5.08%) and stage IV (1.7%); however, vitamin D levels did not statistically differ among these stages. All these patients except stage IV underwent surgery, were followed for two years, and had a survival rate of 90 percent. Conclusion: There was a positive association between vitamin D deficiency and the occurrence of gastric cancer. Vitamin D levels were significantly associated with different tumour differentiation grades but not with clinical staging.

导言:尽管维生素 D 缺乏和胃癌的发病率很高,但我国尚未研究维生素 D 水平与胃癌之间的关系。患者和方法:这是一项为期 26 个月的病例系列分析研究,以 59 名经组织学确诊的胃癌患者和 60 名年龄与性别相匹配的怀疑感染幽门螺杆菌的患者作为对照,以找出低 25 羟基维生素 D 水平与恶性肿瘤之间的关系。研究结果病例和对照组的平均年龄分别为 57 SD(标准差)10 岁和 56 SD 9 岁。病例和对照组的平均维生素 D 水平分别为 20.15 纳克/毫升和 32.21 纳克/毫升,差异有统计学意义(p < 0.0001)。只有 3 名(5%)对照组显示维生素 D 缺乏(< 20 ng/ml),而病例有 30 名(50.84%),差异有统计学意义(p < 0.001)。分化良好、中度分化和分化不良腺癌的平均维生素 D 水平分别为 26.10、23.25 和 14.88 纳克/毫升,差异有统计学意义(p <0.001)。Ⅲ期胃腺癌(50.8%)最常见,其次是Ⅱ期(42.4%)、Ⅰ期(5.08%)和Ⅳ期(1.7%);然而,维生素 D 水平在这些分期中没有统计学差异。除 IV 期外,所有这些患者都接受了手术,随访两年,存活率为 90%。结论维生素 D 缺乏与胃癌的发生呈正相关。维生素 D 水平与不同的肿瘤分化等级有明显关系,但与临床分期无关。
{"title":"Association between Gastric Cancer and Vitamin D in Kashmiri Population: A 2 Year Case–Control Study at a Tertiary Care Hospital","authors":"Younis Mushtaq, Shariq Rashid Masoodi, Mubashir Shah, Ajaz Qadir","doi":"10.1007/s12262-024-04152-4","DOIUrl":"https://doi.org/10.1007/s12262-024-04152-4","url":null,"abstract":"<p>Introduction: The association between vitamin D level and gastric cancer has not been studied in our population despite the high prevalence of vitamin D deficiency and gastric cancer. Patients and Methods: This was a 26-month case series analysis study in which 59 patients with histologically confirmed gastric cancer and age and sex-matched 60 patients with suspicion of <i>Helicobacter Pylori </i>infection were taken as controls to find out any association between low 25 hydroxy vitamin D level and malignancy. Results: The mean age of the cases and controls was 57 SD (standard deviation)10 and 56 SD 9 years, respectively. The mean vitamin D levels in cases and controls were 20.15 ng/ml and 32.21 ng/ml, which was statistically significant (<i>p</i> &lt; 0.0001). Only 3 (5%) controls showed vitamin D deficiency (&lt; 20 ng/ml), compared to 30 (50.84%) cases, which was statistically significant (<i>p</i> &lt; 0.001). The mean vitamin D levels in well differentiated, moderately differentiated and poorly differentiated adenocarcinoma were 26.10, 23.25 and 14.88 ng/ml, respectively, which was statistically significant (<i>p</i> &lt; 0.001). Stage III gastric adenocarcinoma (50.8%) was the most common, followed by stage II (42.4%), stage I (5.08%) and stage IV (1.7%); however, vitamin D levels did not statistically differ among these stages. All these patients except stage IV underwent surgery, were followed for two years, and had a survival rate of 90 percent. Conclusion: There was a positive association between vitamin D deficiency and the occurrence of gastric cancer. Vitamin D levels were significantly associated with different tumour differentiation grades but not with clinical staging.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142178098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Urogenital Functions after Transanal and Laparoscopic Total Mesorectal Excision 经肛门和腹腔镜中直肠全切除术后泌尿系统功能的比较
IF 0.4 4区 医学 Q4 SURGERY Pub Date : 2024-09-07 DOI: 10.1007/s12262-024-04151-5
Jinchun Cong, Hong Zhang, Chunsheng Chen, Kun Xu

Urogenital dysfunction after rectal surgery is associated with neurovascular bundle (NVB) injury. We compared urinary and sexual functions after transanal total mesorectal excision (taTME) and laparoscopic total mesorectal excision (laTME), and analysed the impact of the differences in NVB injuries on the functional outcomes of these treatments. Overall, 187 patients with rectal cancer who underwent taTME (n = 94) or laTME (n = 93) at the Shengjing Hospital of China Medical University between March 2018 and June 2021 were included. Ninety-seven patients (taTME, n = 52; laTME, n = 45) with NVB injuries were classified as bleeding subgroups and the others as non-bleeding subgroups. Urinary function was compared 6 and 12 months postoperatively using the International Prostate Symptom Score (IPSS). Sexual function was compared 12 months postoperatively using the five-item International Index of Erectile Function (IIEF-5). The IPSS of all groups at 6 months postoperatively was higher than that preoperatively. All postoperative scores in the bleeding subgroup of the taTME group were significantly higher than the preoperative scores. The bleeding subgroup of the taTME group had higher IPSS and significantly lower IIEF-5 scores than the non-bleeding subgroup of the taTME group and the bleeding subgroup of the laTME group postoperatively. The IIEF-5 scores of all groups at 12 months postoperatively were lower than those preoperatively. This study confirmed impaired urinary and sexual functions after taTME and laTME, and patients with NVB injuries in the taTME group had worse urinary and sexual dysfunction.

直肠手术后的泌尿生殖功能障碍与神经血管束(NVB)损伤有关。我们比较了经肛门全直肠系膜切除术(taTME)和腹腔镜全直肠系膜切除术(laTME)后的排尿功能和性功能,并分析了神经血管束损伤的差异对这些治疗方法的功能结果的影响。共纳入2018年3月至2021年6月期间在中国医科大学附属盛京医院接受taTME(n = 94)或laTME(n = 93)治疗的187例直肠癌患者。97名NVB损伤患者(taTME,n = 52;laTME,n = 45)被分为出血亚组,其他患者被分为非出血亚组。使用国际前列腺症状评分(IPSS)对术后 6 个月和 12 个月的排尿功能进行比较。术后 12 个月,使用五项国际勃起功能指数(IIEF-5)对性功能进行比较。所有组别术后 6 个月的 IPSS 均高于术前。taTME 组出血亚组的所有术后评分均明显高于术前评分。与 taTME 组的非出血亚组和 laTME 组的出血亚组相比,taTME 组的出血亚组术后 IPSS 更高而 IIEF-5 评分明显更低。所有组别在术后 12 个月的 IIEF-5 评分均低于术前。这项研究证实,taTME 和 laTME 术后泌尿和性功能受损,taTME 组 NVB 损伤患者的泌尿和性功能障碍更严重。
{"title":"Comparison of Urogenital Functions after Transanal and Laparoscopic Total Mesorectal Excision","authors":"Jinchun Cong, Hong Zhang, Chunsheng Chen, Kun Xu","doi":"10.1007/s12262-024-04151-5","DOIUrl":"https://doi.org/10.1007/s12262-024-04151-5","url":null,"abstract":"<p>Urogenital dysfunction after rectal surgery is associated with neurovascular bundle (NVB) injury. We compared urinary and sexual functions after transanal total mesorectal excision (taTME) and laparoscopic total mesorectal excision (laTME), and analysed the impact of the differences in NVB injuries on the functional outcomes of these treatments. Overall, 187 patients with rectal cancer who underwent taTME (<i>n</i> = 94) or laTME (<i>n</i> = 93) at the Shengjing Hospital of China Medical University between March 2018 and June 2021 were included. Ninety-seven patients (taTME, <i>n</i> = 52; laTME, <i>n</i> = 45) with NVB injuries were classified as bleeding subgroups and the others as non-bleeding subgroups. Urinary function was compared 6 and 12 months postoperatively using the International Prostate Symptom Score (IPSS). Sexual function was compared 12 months postoperatively using the five-item International Index of Erectile Function (IIEF-5). The IPSS of all groups at 6 months postoperatively was higher than that preoperatively. All postoperative scores in the bleeding subgroup of the taTME group were significantly higher than the preoperative scores. The bleeding subgroup of the taTME group had higher IPSS and significantly lower IIEF-5 scores than the non-bleeding subgroup of the taTME group and the bleeding subgroup of the laTME group postoperatively. The IIEF-5 scores of all groups at 12 months postoperatively were lower than those preoperatively. This study confirmed impaired urinary and sexual functions after taTME and laTME, and patients with NVB injuries in the taTME group had worse urinary and sexual dysfunction.</p>","PeriodicalId":13391,"journal":{"name":"Indian Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142178120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Indian Journal of Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1