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Integrating disaster risk management into occupational health services: a framework for technological hazard resilience in high-risk industries. 将灾害风险管理纳入职业保健服务:高风险行业技术灾害复原力框架。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-10-01 DOI: 10.2486/indhealth.2025-0068
Nursuhaili Mohd Amin, Hairul Nazmin Nasruddin, Alia Azmi

This paper proposes a novel conceptual framework that integrates Disaster Risk Management (DRM) into Occupational Health Services (OHS) to improve resilience against technological hazards in high-risk industrial sectors. Even though OHS is meant to safeguard the workplace, it lacks systematic management for disaster risks such as chemical spills, industrial fires and toxic releases. To address this gap, the proposed framework synthesizes two internationally recognized models: the WHO's Health Emergency and Disaster Risk Management (Health-EDRM) strategy and the Basic Occupational Health Services (BOHS) model. The integration is structured across three interconnected pillars: (1) Risk Governance and Policy Alignment, (2) Proactive Risk Assessment and Preparedness, and (3) Emergency Response and Resilience-Building. This approach extends the scope of OHS from traditional hazard control and compliance to proactive disaster resilience, offering a new theoretical and practical model tailored for vulnerable and complex industrial environments. In doing so, the framework supports Sustainable Development Goals (SDGs) by enhancing worker protection, business continuity and community-level sustainability. It also lays the foundation for future empirical research and offers actionable guidance for industry leaders and policymakers.

本文提出了一个新的概念框架,将灾害风险管理(DRM)整合到职业卫生服务(OHS)中,以提高高风险工业部门对技术危害的抵御能力。尽管职业健康安全旨在保护工作场所,但它缺乏对化学品泄漏、工业火灾和有毒物质释放等灾害风险的系统管理。为了弥补这一差距,拟议的框架综合了两种国际公认的模式:世卫组织的卫生突发事件和灾害风险管理(Health- edrm)战略和基本职业卫生服务(BOHS)模式。整合的结构跨越三个相互关联的支柱:(1)风险治理和政策协调,(2)主动风险评估和准备,以及(3)应急响应和复原力建设。这种方法将职业健康安全的范围从传统的危害控制和合规扩展到主动的灾难恢复能力,为脆弱和复杂的工业环境提供了一种新的理论和实践模型。在此过程中,该框架通过加强工人保护、业务连续性和社区层面的可持续性来支持可持续发展目标(sdg)。为未来的实证研究奠定了基础,并为行业领导者和决策者提供了可操作的指导。
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引用次数: 0
Workplace situations and alcohol consumption: a review of the literature. Rationale for the occupational physician. 工作环境与饮酒:文献综述。职业医生的基本原理。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-23 DOI: 10.2486/indhealth.2025-0123
Mathura Murugavel, Diane Godeau, Bénédicte Barbotin, Michel Lejoyeux, François Guillon, Aïcha El Khatib

The aim of this work is to identify occupational situations that are at risk and/or encourage alcohol use, whatever the type of consumption. This is a review of the literature in search of articles published between 1989 and August 2019, dealing with the effects of work situations on alcohol consumption. A qualitative analysis was conducted on the articles meeting the selection criteria, and the data were summarised based on the main risk factors identified. There is some evidence supporting work organisation as being at risk of alcohol consumption. This concerns mainly shift work and long-working hours, although the relation with drinking behaviours seems to be conflicting. Social relations and interactions within the workplace may induce (or be at risk of) alcohol consumption, particularly in the case of tolerant standards. The results regarding work stress are contradictory. Data regarding physical workload are scarce. Most studies addressed alcohol consumption as a public health issue, in the labour force, and not as an occupational health issue focused on work situations and conditions. Yet this knowledge may help the occupational physician to question the work environment, in order to prevent this risk on a collective technical level and on an individual case-by-case basis.

这项工作的目的是确定有风险的职业情况和/或鼓励使用酒精,无论哪种类型的消费。这是对1989年至2019年8月期间发表的关于工作环境对饮酒影响的文章的文献综述。对符合选择标准的文章进行定性分析,并根据确定的主要危险因素对数据进行总结。有一些证据表明,工作组织存在饮酒的风险。这主要涉及轮班工作和长时间工作,尽管它们与饮酒行为的关系似乎是相互矛盾的。工作场所内的社会关系和互动可能导致(或面临)饮酒的风险,特别是在容忍标准的情况下。关于工作压力的结果是矛盾的。关于物理工作负载的数据很少。大多数研究将饮酒视为劳动力中的公共卫生问题,而不是关注工作环境和条件的职业卫生问题。然而,这些知识可以帮助职业医生质疑工作环境,以便在集体技术水平和个人个案基础上预防这种风险。
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引用次数: 0
The relationship between employment status and mental health among adults of different groups in Taiwan: a study with artistic leisure as a moderator. 台湾不同族群成人就业状况与心理健康之关系:以艺术休闲为调节因子之研究。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-23 DOI: 10.2486/indhealth.2025-0079
Chieh-Jan Chen, Ching-Mei Hsieh, Sheryl Chen, Albert Chen

The relationship between the employment status and mental health is well established, yet the behavioural mechanisms underlying this association across age groups remain unclear. This study investigates whether artistic leisure moderates the association between employment status and mental health, measured with the 12-item Chinese Health Questionnaire (CHQ-12), using nationally representative survey data from Taiwanese adults aged 18 and above. Participants were categorised into three groups. Descriptive statistics summarised mental health prevalence, and χ2 tests assessed associations across age groups. Hierarchical multivariable logistic regression, adjusted for sociodemographic factors, religious affiliation, financial sufficiency, and physical health, was employed to examine the relationship. The prevalence of good mental health was highest among older adults (84.83%), followed by young (79.25%) and middle-aged adults (78.76%). Artistic leisure significantly moderated the association between employment and mental health in young adults, with those in employment who engaged in artistic activities reporting better outcomes (AOR=4.22, 95% CI: 1.98-8.96). No significant moderating association was found in the older age groups. These findings suggest that employment plays a critical role in the mental well-being of young adults, highlighting the importance of understanding the contexts and motivations behind their engagement in artistic leisure.

就业状况与心理健康之间的关系已经确立,但这种关联在各年龄组之间的行为机制尚不清楚。本研究以台湾18岁及以上成人为研究对象,采用12项华人健康问卷(CHQ-12),探讨艺术休闲是否能调节就业状况与心理健康之间的关系。参与者被分为三组。描述性统计总结了心理健康的流行情况,并用χ2检验评估了各年龄组之间的关联。采用分层多变量logistic回归,调整了社会人口因素、宗教信仰、财政充足性和身体健康,来检验两者之间的关系。心理健康状况良好的人群以老年人最高(84.83%),其次是年轻人(79.25%)和中年人(78.76%)。艺术休闲显著调节了年轻人就业与心理健康之间的关系,从事艺术活动的就业人员报告了更好的结果(AOR=4.22, 95% CI: 1.98-8.96)。在老年人群中没有发现显著的调节关联。这些发现表明,就业在年轻人的心理健康中起着至关重要的作用,强调了理解他们参与艺术休闲背后的背景和动机的重要性。
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引用次数: 0
Subjective and objective fatigue dynamics in air traffic control. 空中交通管制主客观疲劳动力学研究。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-20 Epub Date: 2025-02-21 DOI: 10.2486/indhealth.2024-0206
Maximilian Peukert, Lea Claus, Lothar Meyer

Fatigue is a longstanding issue in air traffic control (ATC), closely associated with shift work and time-related factors. However, the dynamics of fatigue across morning, evening, and night shifts in an area control center (ACC) remain largely underexplored. This study examined sleep duration and fatigue progression across different shift types. Both objective (three-minute Psychomotor Vigilance Task, PVT-B) and subjective (Stanford Sleepiness Scale, SSS) measures were conducted at the beginning, middle, and end of each shift. Results indicated that pre-shift sleep duration was shortest before night shifts, likely increasing sleep pressure and reducing alertness during the window of circadian low (WOCL). Subjective fatigue remained stable throughout morning shifts but increased towards the end of evening shifts, reflecting circadian influences. Night shifts exhibited peak fatigue during the WOCL, driven primarily by circadian rhythms rather than task load. Objective measures revealed a mid-shift decline in performance, with only partial recovery in the latter half of night shifts. Compared to day shifts, night shifts resulted in significantly higher fatigue levels, underscoring the critical role of circadian rhythms in fatigue dynamics. These findings highlight the need for targeted fatigue mitigation strategies that address circadian vulnerabilities and irregular sleep patterns in ATC shift systems.

疲劳是空中交通管制(ATC)长期存在的问题,与轮班工作和时间相关因素密切相关。然而,在区域控制中心(ACC)的早、晚、夜班中,疲劳的动态仍未得到充分研究。这项研究调查了不同轮班类型的睡眠时间和疲劳程度。客观(三分钟精神运动警觉性任务,PVT-B)和主观(斯坦福嗜睡量表,SSS)测量分别在每班的开始、中间和结束时进行。结果表明,夜班前的睡眠时间最短,可能增加了睡眠压力,降低了昼夜节律低窗口(WOCL)的警觉性。主观疲劳在早班期间保持稳定,但在晚班结束时增加,反映了昼夜节律的影响。夜班在WOCL期间表现出最大的疲劳,主要是由昼夜节律而不是任务负荷驱动的。客观的测量显示,在轮班中期,表现下降,只有部分恢复在夜班后半段。与白班相比,夜班导致明显更高的疲劳水平,强调昼夜节律在疲劳动力学中的关键作用。这些发现强调需要有针对性的疲劳缓解策略,以解决空中交通管制轮班系统中的昼夜节律脆弱性和不规则睡眠模式。
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引用次数: 0
Association between work stress and sleep disturbances: the mediating role of pre-sleep arousal symptoms. 工作压力与睡眠障碍之间的关系:睡眠前唤醒症状的中介作用。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-20 Epub Date: 2025-03-17 DOI: 10.2486/indhealth.2024-0158
Jeehee Min, Hoje Ryu, Seong-Sik Cho, Mo-Yeol Kang

This study investigated the association between work stress and sleep disturbance among Korean workers, focusing on the mediating effects of somatic and cognitive pre-sleep arousal symptoms. Data were derived from the "Korean Work, Sleep, and Health Study (KWSHS)", involving 4,393 participants. Work stress was assessed using the Korean Occupational Stress Scale, and sleep disturbances were measured using the Insomnia Severity Index and Pittsburgh Sleep Quality Index. The Pre-Sleep Arousal Scale was utilized for assessing pre-sleep arousal status. For statistical analyses, the chi-square test, logistic regression analysis, and mediation analysis were used. Mediation analysis revealed that somatic pre-sleep arousal predominantly mediated the relationship between hazardous physical environments and insomnia symptoms (52.5%), while cognitive pre-sleep arousal was the primary mediator for high job demands (48.0%), organizational injustice (48.6%), and job insecurity (46.6%). These findings suggest that somatic and cognitive pre-sleep arousal serve distinct mediating roles in the relationship between specific types of work stress and sleep disturbances.

本研究调查了韩国工人的工作压力与睡眠障碍之间的关系,重点关注体细胞和认知睡眠前唤醒症状的中介作用。数据来自“韩国工作、睡眠和健康研究(KWSHS)”,涉及4393名参与者。使用韩国职业压力量表评估工作压力,使用失眠严重程度指数和匹兹堡睡眠质量指数测量睡眠障碍。使用睡眠前唤醒量表评估睡眠前唤醒状态。统计学分析采用χ2检验、logistic回归分析和中介分析。中介分析显示,躯体性睡眠前唤醒在危险物理环境与失眠症状的关系中起主导作用(52.5%),而认知性睡眠前唤醒在高工作要求(48.0%)、组织不公正(48.6%)和工作不安全感(46.6%)之间起主要中介作用。这些发现表明,在特定类型的工作压力和睡眠障碍之间的关系中,身体和认知的睡眠前唤醒起着不同的中介作用。
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引用次数: 0
Supporting the well-being of nurses, paramedics, and firefighters during external crises by managing workload: an umbrella review. 通过管理工作量,在外部危机期间支持护士、护理人员和消防员的福祉:总括性审查。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-20 Epub Date: 2025-03-14 DOI: 10.2486/indhealth.2024-0211
Kati Karhula, Janne Halonen, Satu Mänttäri, Anne Punakallio, Sampsa Puttonen, Maria Sihvola, Pihla Säynäjäkangas, Mikael Sallinen

Support is needed for the well-being of nurses and first responders in external crises. We aimed to synthesize the evidence between workload management strategies and well-being of nurses, paramedics, and firefighters during external crises in an umbrella review. The data sources OVID Medline, APA PsycInfo, CINAHL, Web of Science and the Cochrane Library were searched between 1.1.2013-20.6.2023. Two independent reviewers assessed the eligibility of the publications and conducted the data extraction and narrative synthesis. The search identified 1,073 references on nurses and 182 on paramedics and firefighters. Of the 62 full texts, 16 systematic reviews on nurses were included, and of the 13 full texts on paramedics and firefighters, two systematic reviews were included, making a total of 18 systematic reviews. The quality of the publications was predominantly good (83%). Both employee and work-directed strategies were beneficial in supporting employee well-being during external crises. Proactive practical skills training and psychological interventions were found as the most promising employee-directed strategies. The corresponding work-directed strategies were effective communication, providing useful information and adequate working conditions, supportive leadership, and peer support. To support well-being of nurses and first responders during external crises, workload management strategies need to be proactively planned in workplaces.

在外部危机中,护士和急救人员的福祉需要得到支持。我们旨在综合外部危机期间工作量管理策略与护士、护理人员和消防员福祉之间的证据。检索OVID Medline、APA PsycInfo、CINAHL、Web of Science和Cochrane Library,检索时间为1.1.2013-20.6.2023。两名独立审稿人评估了出版物的合格性,并进行了数据提取和叙述综合。搜索发现了1073条关于护士的信息,182条关于护理人员和消防员的信息。在62篇全文中,包括16篇关于护士的系统评价,在13篇关于护理人员和消防员的全文中,包括2篇系统评价,总共有18篇系统评价。出版物的质量以良好为主(83%)。在外部危机期间,员工和工作导向策略都有利于支持员工的幸福感。积极主动的实践技能培训和心理干预是最有前途的员工导向策略。相应的以工作为导向的策略是有效的沟通,提供有用的信息和适当的工作条件,支持性领导和同伴支持。为了在外部危机期间支持护士和急救人员的福祉,需要在工作场所积极规划工作量管理战略。
{"title":"Supporting the well-being of nurses, paramedics, and firefighters during external crises by managing workload: an umbrella review.","authors":"Kati Karhula, Janne Halonen, Satu Mänttäri, Anne Punakallio, Sampsa Puttonen, Maria Sihvola, Pihla Säynäjäkangas, Mikael Sallinen","doi":"10.2486/indhealth.2024-0211","DOIUrl":"10.2486/indhealth.2024-0211","url":null,"abstract":"<p><p>Support is needed for the well-being of nurses and first responders in external crises. We aimed to synthesize the evidence between workload management strategies and well-being of nurses, paramedics, and firefighters during external crises in an umbrella review. The data sources OVID Medline, APA PsycInfo, CINAHL, Web of Science and the Cochrane Library were searched between 1.1.2013-20.6.2023. Two independent reviewers assessed the eligibility of the publications and conducted the data extraction and narrative synthesis. The search identified 1,073 references on nurses and 182 on paramedics and firefighters. Of the 62 full texts, 16 systematic reviews on nurses were included, and of the 13 full texts on paramedics and firefighters, two systematic reviews were included, making a total of 18 systematic reviews. The quality of the publications was predominantly good (83%). Both employee and work-directed strategies were beneficial in supporting employee well-being during external crises. Proactive practical skills training and psychological interventions were found as the most promising employee-directed strategies. The corresponding work-directed strategies were effective communication, providing useful information and adequate working conditions, supportive leadership, and peer support. To support well-being of nurses and first responders during external crises, workload management strategies need to be proactively planned in workplaces.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":"414-430"},"PeriodicalIF":1.6,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of mental disorders among education and learning-support workers in 119 compensated cases in Japan. 日本119例教育和学习支持工作者的精神障碍特征
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-20 Epub Date: 2025-03-10 DOI: 10.2486/indhealth.2024-0101
Yuki Takahashi, Toru Yoshikawa, Kenji Yamamoto, Masaya Takahashi

This study aimed to investigate the circumstances, characteristics, and background factors of mental disorders within the education and learning-support services, which is known for the frequent occurrence of mental disorders from overwork and poor psychosocial work environment. The study analyzed 119 cases of mental disorders and suicides in the education and learning-support services from fiscal years 2010 to 2019 on the database constructed by the Japan Research Center for Overwork-Related Disorders. The results exhibit that of 119 cases, 56 cases (47.1%) involved male employees while 63 cases (52.9%) involved female employees. From fiscal years 2010 to 2019, there were 43 cases of psychological stress related to work among males and 55 among females. The issue of "interpersonal relationship" was significantly higher in the education and learning-support services than in other industrial workers. Within the category of "interpersonal relationship" the specific issue of being "(severely) harassed, bullied, or assaulted" was especially prevalent (10 cases for males and 15 cases for females). Moreover, male employees reported many instances of suicide attempts, and their first attempt tended to lead to a completed suicide. Therefore, it is important to promote measures against harassment, bullying, and suicide in education and learning-support services.

摘要本研究旨在探讨教育及学习支援服务机构中,因过度工作及社会心理环境差而导致精神障碍的情况、特点及背景因素。该研究利用日本工作过度障碍研究中心建立的数据库,分析了2010 - 2019财年教育和学习支持服务部门的119例精神障碍和自杀案例。结果显示,119例中男性员工56例(47.1%),女性员工63例(52.9%)。从2010财年到2019财年,男性有43例与工作有关的心理压力,女性有55例。在教育和学习支持服务中,“人际关系”问题明显高于其他产业工人。在“人际关系”类别中,被“(严重)骚扰、欺凌或殴打”的具体问题尤其普遍(男性10例,女性15例)。此外,男性员工报告了许多自杀未遂的案例,他们的第一次尝试往往导致最终自杀。因此,在教育和学习支持服务中促进防止骚扰、欺凌和自杀的措施非常重要。
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引用次数: 0
Associations of employment status, working time and job satisfaction with sleep duration and sleep quality among the 50+ population in Japan. 日本 50 岁以上人群的就业状况、工作时间和工作满意度与睡眠时间和睡眠质量的关系。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-20 Epub Date: 2025-03-14 DOI: 10.2486/indhealth.2024-0131
Jacques Wels, Rong Fu

Few studies have addressed the relationship between sleep and employment in Japan. We use four waves of the Japan Study of Aging and Retirement (JSTAR) to address the relationship between weekday sleep duration, self-reported sleep quality and four self-reported indicators of sleep quality and employment status (model 1, full sample), working hours and job satisfaction (model 2, working sample) among individuals aged 50 and over (N=7,082). We apply mixed effects models for the linear outcome of sleep duration and cumulative link mixed models for the sleep quality variables, controlling for socio-demographic and health characteristics. In model 1, our findings show that, compared to full-time employees, all categories of workers and non-workers report longer sleep hours. Some sub-groups, such as contract workers, report higher odds of waking up at night or in the early morning, and taking a longer time to fall asleep. In model 2, we find a positive association between working time and sleep hours but including job satisfaction in the model absorbs such a relationship, indicating the job satisfaction somehow reflects working time. Poor job satisfaction is linked to higher odds of experiencing difficulties in four of the five sleep quality measures.

在日本,很少有研究涉及睡眠和就业之间的关系。我们使用日本老龄化与退休研究(JSTAR)的四个波来解决50岁及以上个体(N=7,082)的工作日睡眠时间,自我报告的睡眠质量和四个自我报告的睡眠质量与就业状况(模型1,全样本),工作时间和工作满意度(模型2,工作样本)之间的关系。我们对睡眠持续时间的线性结果应用混合效应模型,对睡眠质量变量应用累积联系混合模型,控制社会人口统计学和健康特征。在模型1中,我们的研究结果表明,与全职员工相比,所有类别的工人和非工人都报告睡眠时间更长。一些细分群体,如合同工,报告称更有可能在晚上或清晨醒来,并且需要更长的时间才能入睡。在模型2中,我们发现工作时间和睡眠时间之间存在正相关关系,但在模型中加入工作满意度吸收了这种关系,说明工作满意度在某种程度上反映了工作时间。工作满意度低与五项睡眠质量指标中四项出现问题的几率较高有关。
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引用次数: 0
Paradox of long working hours: how income levels and satisfaction modify health outcomes. 长时间工作的悖论:收入水平和满意度如何改变健康结果。
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-20 Epub Date: 2025-03-04 DOI: 10.2486/indhealth.2024-0171
Jeehee Min, Min-Seok Kim, Dong-Wook Lee, Seong-Sik Cho, Mo-Yeol Kang

This study investigates how household income levels and satisfaction with income impact the relationship between long working hours and self-rated health (SRH) among Korean workers. We analysed data from the Korean Labour & Income Panel Study spanning 2018 to 2022, including 8,954 to 10,079 wage workers annually. Weekly working hours and SRH were the primary variables, with equivalized household income levels classified into quartiles. A generalised estimating equation was used to assess the relationship between long working hours and poor SRH, adjusted for demographic and health-related factors. Subgroup analyses were conducted based on household income level and satisfaction. Long working hours were generally associated with poor SRH (OR 1.30, 95% CI 1.10-1.54) in unadjusted model, particularly among higher-income groups (OR 1.46, 95% CI 1.05-2.01 for Q4) after adjustment for covariates. However, no significant association was found for lower-income groups. When stratified by income satisfaction, longer working hours were significantly associated with poor SRH only in income-satisfied individuals among higher-income group. The health effects of long working hours may differ according to household income levels and satisfaction. Policy interventions should consider both work hour reductions and income adequacy to improve worker health.

本研究探讨家庭收入水平与收入满意度如何影响韩国工人长时间工作与自评健康(SRH)之间的关系。我们分析了2018年至2022年韩国劳动和收入小组研究的数据,其中包括每年8,954至10,079名工薪阶层。每周工作时间和SRH是主要变量,同等家庭收入水平分为四分位数。使用一个广义估计方程来评估长工作时间与低性健康和生殖健康之间的关系,并根据人口统计学和健康相关因素进行了调整。根据家庭收入水平和满意度进行亚组分析。在未调整的模型中,长时间工作通常与较差的SRH相关(OR 1.30, 95% CI 1.10-1.54),特别是在调整协变量后的高收入群体中(OR 1.46, 95% CI 1.05-2.01)。然而,在低收入群体中没有发现显著的关联。当按收入满意度分层时,较长的工作时间仅在高收入群体中收入满意的个体中与较差的SRH显著相关。长时间工作对健康的影响可能因家庭收入水平和满意度而异。政策干预应考虑减少工作时间和收入是否充足,以改善工人健康。
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引用次数: 0
High serum perfluorooctanoic acid (PFOA) concentrations and interstitial lung disease in former and current workers in a fluorochemical company. 某氟化工公司职工血清全氟辛酸(PFOA)高浓度与间质性肺疾病
IF 1.6 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2025-09-20 Epub Date: 2025-04-22 DOI: 10.2486/indhealth.2025-0009
Kunio Kanetani, Kenji Nakamura, Kouji H Harada, Hideaki Akihisa, Tamiki Oshima, Hiromi Ogata, Akio Koizumi

In 2002, Daikin Industries' Yodogawa Plant (DIYP) in Settsu City in Japan had contaminated drinking water in Hanshin area with (PFOA), leading to the complete cessation of PFOA production in 2012. In 2023, local residents conducted a voluntary Blood Monitoring Campaign with 1,182 general residents. Blood monitoring was also conducted for former or current workers from DIYP and farming residents in Settsu City. Serum PFOA concentrations determined by gas chromatography with mass spectrometry [number: ng/ml: median (25th-75th percentile)] were as follows: former and current workers [N=7: 192.6 (23.3-596.6)] >farming residents [N=5: 70.2 (50.4-98.8)] >general residents [N=1182: 5.0 (3.3-7.0)] with significant differences (Kruskal-Wallis test, p<0.001). In a study, 4 out of 5 farming residents showed a serum PFOA decline (half-life: 2.2 yr, 95% CI: 1.4-4.6) after stopping local agricultural product consumption. However, 3 former workers exhibited no decrease over 0.8-0.9 yr. An investigation found that 5 of the 7 subjects were likely exposed to dust from the polymerization of tetrafluoroethylene or handling its particulate matters, with 3 showing Interstitial Lung Disease (ILD) signs. This suggests PFOA-laden dust may delay excretion and contribute to ILD, though the mechanistic link remains unclear, requiring further research.

2002年,日本濑津市大金工业的代道川工厂(DIYP)用全氟辛酸(PFOA)污染了阪神地区的饮用水,导致2012年完全停止了全氟辛酸的生产。2023年,当地居民对1182名普通居民进行了自愿血液监测运动。还对DIYP的前任或现任工人和setsu市的农业居民进行了血液监测。气相色谱-质谱法测定的血清PFOA浓度[数值:ng/mL:中位数(25 -75个百分点)]分别为:以前和现在的工人[N=7: 192.6(23.3-596.6)];农业居民[N=5: 70.2(50.4-98.8)];普通居民[N=1 182: 5.0(3.3-7.0)],差异有统计学意义(Kruskal-Wallis检验,p
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引用次数: 0
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