Industrial laboratory. Diagnostics of materials最新文献

{"title":"Non-destructive colorimetric analysis of drugs for fluoroquinolones using a smartphone","authors":"V. G. Amelin, O. E. Emelyanov","doi":"10.26896/1028-6861-2024-90-1-17-25","DOIUrl":"https://doi.org/10.26896/1028-6861-2024-90-1-17-25","url":null,"abstract":"","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139609305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chromatographic determination of iodoacetate in lipid nanostructures","authors":"D. Korshunov, I. A. Kondakova, E. Sidenko, E. Sereda, N. Y. Zolotukhina","doi":"10.26896/1028-6861-2023-89-12-5-12","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-5-12","url":null,"abstract":"A liposomal form of anticancer drugs is often used to improve pharmacokinetics and reduce systemic toxicity of the drugs. The goal of the study is to develop a method for quantitative analysis of a liposomal form of sodium iodoacetate (IA), glycolysis inhibitor, which exhibits a pronounced antitumor activity. Liposomes were prepared by extrusion at a temperature of 25 – 55°C under argon pressure ranged from 2 to 10 MPa. The obtained liposomes were purified from the non-incorporated component using dialysis. The method of HPLC was used to analyze the inhibitor solution in liposomes. The method of hydrophilic interaction chromatography revealed a high selectivity of iodoacetate with aminopropyl silica gel as a stationary phase. The best option for analysis was to use a spectrophotometric detector. The results of analysis showed that the dose of the inhibitor in 1 ml of liposomes was 0.20 – 0.23 mg regardless of the liposome size. In terms of the weight of an animal, the amount of iodoacetate was 8 – 9 mg/kg. The analysis of liposomes by the developed method showed that the highest yield and a high degree of purification is attained at low temperature (no more than 40°C) and duration of dialysis for about 3 h. For these purposes, the use of liposomes with a diameter of 400 nm turned out to be the best option.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138965171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studying the effect of the argon flow introduced into the arc discharge in the atomic-emission spectrometry of powdered samples using the spillage-injection method","authors":"S. Dodonov, A. A. Dzyuba, V. А. Labusov","doi":"10.26896/1028-6861-2023-89-12-13-21","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-13-21","url":null,"abstract":"Atomic emission spectral analysis of a powder sample by the method of spillage-injection into the plasma of an arc discharge burning in air is accompanied by the formation of cyanide, nitride and oxide compounds which form molecular bands in the spectrum thus impeding measuring the intensity of the analytical lines of the elements to be determined. Feeding an argon flow into the arc discharge can reduce the amount of spectral interference and increase the plasma temperature, which promotes more a complete evaporation of the analyzed sample injected into the arc discharge and, accordingly, increases the degree of ionization of the elements and the intensity of ion spectral lines. The aim of the study was to develop a device for argon introduction into the arc discharge zone and simultaneous sample delivery by a spillage-injection method, as well as to study the effect of argon consumption on arc discharge parameters and emission spectra of powder samples. The argon input device (up to 2.25 L/min) is developed on the basis on glass funnels, the geometric dimensions of which are selected with the goal of gaining the maximum intensity of spectral lines and reduced intensity of molecular bands at the minimal argon consumption. The study carried out on a «Grand Potok» spectrometer demonstrated that with an increase in argon consumption, the intensity of SiO molecular bands decreases, the plasma temperature increases by 350 – 540 K, and the intensity of ion and atomic lines with the ionization energy above 8 eV increases by more than 4.7 and 2.9 times, respectively. The developed device can be used in analysis of geological materials to improve the metrological characteristics of the results of atomic emission spectral analysis.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of iron in water by flame atomic absorption spectrometry with sorption preconcentration","authors":"U. U. Ruzmetov, E. S. Jumaeva, B. T. Orziqulov, Z. A. Smanova","doi":"10.26896/1028-6861-2023-89-12-22-30","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-22-30","url":null,"abstract":"Determination and monitoring of pollutants in the natural environment is an urgent task because of their impact on living organisms as a result of numerous anthropogenic impacts. For this reason, a large number of publications are devoted to the development, modification or optimization of analytical methods that can solve these problems. When determining trace elements present in various samples, such as natural and waste water, biological samples and alloy samples, direct determination by various instrumental methods is often impossible due to the matrix effect and rather low concentration of metal ions in the sample. The atomic absorption method is one of the methods widely used for the determination of iron ions, which has such advantages as simplified sample preparation, low probability of contamination and loss of elements, increased analytical productivity, the detection limit of components in the analyzed mixture reduced by several orders of magnitude, and the ability to determine trace amounts of elements in small samples. The aim of the study was to develop a technique for the preliminary concentration of Fe (III) ions in waters of various origins using a sorbent immobilized with sulfosalicylic acid and their further determination by flame atomic absorption spectrometry. Sorbents obtained on the basis of polyacrylonitrile modified with polyethylene polyamine (PPF-1 and PPA-1) with sulfosalicylic acid immobilized on their surface were used for selective sorption of Fe (III) ions. Optimal conditions for the immobilization of sulfosalicylic acid on sorbents and the formation of complexes with Fe (III) ions were studied. The developed sorption-atomic absorption technique provided determination of low concentrations of Fe (III) ions in various waters. The use of PPF-1 as a sorbent with immobilized sulfosalicylic acid for pre-concentration of iron has a number of advantages compared to traditional atomic absorption procedure, i.e., the simplicity, high degree of iron extraction, high sensitivity and selectivity of iron determination, as well as a low cost. The detection limit of iron ions is 0.01 μg/L, Sr does not exceed 0.033.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of the structure of yttrium-based nanoporous ceramic materials","authors":"R. Kapustin, V. I. Uvarov, A. O. Kirillov, V. O. Koputsky","doi":"10.26896/1028-6861-2023-89-12-53-59","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-53-59","url":null,"abstract":"Porous ceramic materials with high filtration performance are widely used in conditions of high chemical, thermal and radiation loads. The results of studying the structure and morphology of the pore space of ceramic membranes are presented. Ultradispersed refractory powder Y2O3 was used as a main component-filler. The synthesis was carried out using compaction, technological combustion and self-propagating high-temperature synthesis. The use of ultradisperse sintering additives with highly developed surface (MgO — 5 μm, SiC — 3, SiO2 — 5 μm) allowed us to ensure the energy efficiency of synthesis of high- porous ceramic materials at low temperatures. Analysis of the structure and pore space using mercury porometry and alternative methods showed that the average pore size in the synthesized 3D matrix composite material based on yttrium orthosilicate matrix with yttrium oxide filler is 1.1 μm, the equivalent hydraulic pore diameter being about 100 nm. The difference is attributed to the variability of cross sections and high tortuosity of pore channels. Since the density of the material is 2.3 g/cm3 and the compressive strength is about 2 MPa, it can be easily machined with carbide tools being a promising material for manufacturing products with complex shapes. The obtained results can be used in developing energy-efficient technologies of one-stage production of yttrium oxide-based filters with high porosity to be used under conditions of exposure to radiation, aggressive media and high temperatures.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the features of inhomogeneous residual stress identification using the digital speckle interferometry and the hole-drilling method","authors":"A. S. Plotnikov, E. Zavoychinskaya","doi":"10.26896/1028-6861-2023-89-12-60-73","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-60-73","url":null,"abstract":"A phenomenological approach to the actual problem of determining the inhomogeneous residual stress-strain state in the components of high-tech engineering systems at the stages of their design and operation is presented. The approach is based on physical and mechanical methods of measuring displacements. Current physical models describe the physical regularities of the residual states attributed to changes in the structure by the interaction of defects and dislocations in the field of micro- and meso-stresses. At the same time, there are the problems of the transition to the macrolevel, the construction of multilevel models, and the conversion of these models in engineering practice. In the framework of phenomenological approaches, in the general case, the solution of this problem requires the solution of three-dimensional inverse problems of thermoelasticity. A well-known mechanical method for determining a uniform field of residual elastic stresses recommended by ASTM E837 is described. The method proposed earlier by one of the authors for determining an inhomogeneous (in the plane) field of residual elastic stresses is discussed. A method of the three-dimensional inhomogeneous residual elastic stress-strain state determination based on the experimental determination of the displacement vector components by the method of step-by-step point hole-drilling and data of digital speckle interferometry and digital image correlation is developed. The constitutive relations for the components of the displacement vector are written in the form of Volterra integral operators. The basic operator functions are the functions of four variables, i.e., the coordinates of the cylindrical system (r, θ, z) associated with the hole, and the hole depth h. A method for verification of the basic functions is presented. The problem is reduced to the determination of three displacement functions of three variables: hole radius r, h, and z. Numerical simulation of basic functions is carried out. The obtained results are consistent with the known experimental data and calculated values of the deformation on the surface depending on the depth of the hole according to the ASTM E837 Standard.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139176127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of the shear characteristics of polymer composite materials","authors":"O. V. Abashev, E. I. Smagin, A. G. Yashutin","doi":"10.26896/1028-6861-2023-89-12-74-80","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-74-80","url":null,"abstract":"Layered polymer composite materials (LPCM) based on carbon fiber and epoxy are widely used in the construction of commercial aircraft both in manufacturing lightly loaded and main power elements of aircraft airframes. The level of mechanical characteristics for all the composite constructions must be confirmed by experimental data of coupon testing. One of the most important characteristics of a layered composite material is the ability to perceive shear loads. Standard test methods ASTM D5379 and ASTM D7078 are used to determine the shear characteristics. These test methods enable determination of the shear properties of composite materials based on a polymer matrix reinforced with a high-modulus fiber. Comparative tests were carried out according to both methods. The samples were made from the wall and the tehnological zones of the spar to determine the values of destructive stresses and shear modulus. The results showed that the shear stresses in the material obtained by ASTMD7078 significantly (1.8 times) exceed those determined by ASTM D5379. At the same time, the modulus of elasticity differs slightly (by 1.1 times). This is due to the sensitivity of the test results to the method of loading and the quality of the specimens. When stretched according to ASTMD7078, the load is transmitted through the front surfaces of the coupons, which are obtained with sufficiently high quality from the tooling or vacuum bag. When compressed by ASTM D5379, the parallelism of the faces through which the load is distributed becomes critical. Moreover, the thickness of the sample also affected the test results obtained according to ASTM D5379, the greater the thickness, the greater the shear modulus. Proceeding from the results obtained, the recommendations on the choice of the method to be used for determining the shear characteristics of LPCM are formulated.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138994722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the electromagnetic properties of 2000NN/2000NM composites with ferroelectric and polymer matrices","authors":"V. Kostishin, R. Shakirzyanov, I. Isaev, E. S. Savchenko, B. M. Skibo","doi":"10.26896/1028-6861-2023-89-12-44-52","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-44-52","url":null,"abstract":"The results of studying the electrical properties of ferrite-dielectric composites containing inclusions of Mn-Zn and Ni-Zn spinel ferrites with the same initial magnetic permeability (grades 2000NM and 2000NN, respectively) and different electrical resistance are presented. Four matrix materials, polymer and ceramic dielectrics with a different dielectric permittivity were used in the experiments: polystyrene (PS525), polyvinylidene fluoride (grade F2MB), lead zirconate titanate (ZTS-21), and barium titanate (TBK-3). Experimental samples of composites were obtained by hot (for a polymer matrix) or cold pressing with a binder (in case of ferroelectric ceramic matrix). It has been shown that the microwave-absorbing properties of the resulting composites significantly depend on the electrical properties of the dielectric matrix and the electrical resistivity of the filler. The highest attenuation of electromagnetic waves of 25 – 27 dB in the frequency range 4 – 5 GHz is observed for ferrite-polymer composites with a semiconductor filler of 2000NM with a thickness of microwave-absorbing material of 6 mm. For composites with Mn-Zn ferrite filler, a pronounced shift in the dispersion region of magnetic permeability is also observed, which in turn changes the frequency position of peak radio absorption. For the composites with a ferroelectric matrix, the operating frequency range for both fillers shifted to the low-frequency region 1 – 4 GHz with a maximum attenuation of up to 22 dB at the same thickness. It was experimentally confirmed that at a concentration of ferrite Cm = 40 % wt., the value of the frequency of absorption peal center fc and the minimum value of the reflection loss Kref for a filler with high electrical resistance of 2000NN decrease with an increase in the dielectric constant of the matrix. As for the composites with a 2000NM filler, the (ε’ of the matrix) dependence passes through a minimum. The obtained composites can be considered as effective microwave-absorbing materials for the frequency range 1 – 6 GHz with peak attenuation of the electromagnetic wave in the range 14 – 27 dB and frequency band (less than 10 dB) in the range 1.1 – 2.5 GHz.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139174880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental determination of the interlayer fracture toughness of a composite material","authors":"I. S. Belousov, V. A. Bespalov","doi":"10.26896/1028-6861-2023-89-12-81-87","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-81-87","url":null,"abstract":"Modeling the propagation of interlaminar defects in multilayer composite materials requires knowledge of the characteristics of the material under study associated with the fracture processes. The goal of the study is determination of the interlaminar fracture toughness in the case of normal traction (GIc). Finite element modeling of testing was carried out proceeding from the data obtained. The delamination process was modeled using the most common approaches within the finite element method: VCCT (virtual crack closure technique) and CZM (cohesive zone model), wherein the fracture toughness is used as the main parameter for the occurrence of delamination. The obtained data are compared with the experiment. To confirm the correctness of the obtained experimental data on the fracture toughness GIc, modeling of the process of compression testing of a strut-type specimen with a defect in the form of a through-the-width delamination was carried out. This problem includes a nonlinear static solution with buckling and subsequent post-buckling behavior, and, as a result, the spread of the delamination zone. The data obtained using finite element modeling are consistent with the available experimental data.","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138994610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the reliability of the forensic technique for the identification study of motor gasoline using gas-liquid chromatography","authors":"G. Bebeshko, G. G. Omel’yanyuk, O. V. Samoilova, A. I. Usov","doi":"10.26896/1028-6861-2023-89-12-31-43","DOIUrl":"https://doi.org/10.26896/1028-6861-2023-89-12-31-43","url":null,"abstract":"A new approach to solving the problems of forensic examination of petroleum products, fuels and lubricants associated with establishing whether motor gasoline belongs to a common/different identification set is proposed. A methodology for the identification of gasoline using quantitative results of chromatographic determination of controlled parameters and subsequent evaluation of the results in pairwise compared samples according to the established criteria. The following parameters were selected as controlled indicators: values of research octane number (RON), concentrations of hydrocarbon groups (paraffins, isoparaffins, arenes, naphthenes, olefins) and oxygenates. Their determination was carried out using standardized methods. We used the hardware and software complex of a Chromatek-Crystal 5000 series, including the Chromatek-DHA data processing program. Estimated criteria or decision- making rules regarding the issues posed to an expert were determined to classify gasoline under one product name (generic set), one production technology (group set) or a common source of origin (one production batch, storage tank, etc.). The reliability of the method was assessed using a validation procedure consisted of three stages. We used a collection of AI-92 motor gasoline, selected at gas stations of four oil companies during six months of 2022 in various districts of Moscow. At the first stage, the performer analyzed 12 aliquots of each of four gasoline samples (samples that previously belonged to the common volume) at different times. It was established that the quality indicators of the proposed methodology (standard deviation of the repeatability and reproducibility, expanded uncertainty, limits of the repeatability and reproducibility) for each of the determined controlled indicators did not exceed the permissible errors established by standardized methods. At the second stage of the experiment, the performer combined 12 test samples into four groups from each manufacturer (one production technology) with three samples of different production times (different batches). By comparing the discrepancies in the measured values of the same controlled indicators between pairs of samples within groups and the discrepancy in average indicators between pairs of groups, the contractor identified gasolines manufactured using the same technology; gasolines produced by the same technology, but at different times (different batches) and, with a probability of 95%, gasolines having a common source of origin (previously belonging to a common volume). The conclusions of the validation study matched the original data on the samples, which confirmed the correctness of the developed comparison criteria. At the third stage (blind test), the performer examined seven gasoline samples of, information about the composition and properties of which was not provided to him. The results of the blind test were considered satisfactory. Thus, the validation results indicate the s","PeriodicalId":13559,"journal":{"name":"Industrial laboratory. Diagnostics of materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}