首页 > 最新文献

Innovation in Aging最新文献

英文 中文
Physical Disability, Service Coordination, & Outcomes in Publicly-Funded Long-Term Services & Supports. 公共资助的长期服务和支持中的身体残疾、服务协调和结果。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-31 eCollection Date: 2025-12-01 DOI: 10.1093/geroni/igaf122.013
Romil Parikh, Dana Urbanski, Chanee Fabius, Stephanie Giordano, Eric Jutkowitz, Tetyana Shippee

People living with physical disability (PD) receiving long-term services & supports (LTSS) experience greater unmet service needs. It is unclear if having a case manager for service coordination modifies PD-associated LTSS outcomes. To fill this knowledge gap, we evaluated associations of PD with emergency department (ED) visits and community integration among older LTSS consumers with and without a case manager. Among 6,756 respondents (age, ≥65 years) from the National Core Indicators- Aging & Disability Survey (2018-2019), we evaluated three dichotomized outcomes (yes vs no): ED visits (over 12 months); and self-reported community integration indicated by both- activity (i.e. being as active in community as preferred) and enjoyment (i.e. enjoying things outside home). We used logistic regression, adjusting for consumers' sociodemographic and health-related characteristics, with random intercept for state. PD was documented in 60% of survey respondents. People living with PD were 27% more likely to report not having a case manager (p < 0.001). Among those without a case manager, PD was associated with significantly greater odds of ED visits (odds ratio [OR], 1.80, 95% CI, 1.48-2.19) and lower odds of community integration [activity: OR, 0.75, 95% CI, 0.62-0.90; enjoyment: OR, 0.69, 95% CI, 0.58-0.83]. These associations were attenuated among consumers with a case manager [ED visits: OR, 1.09, 95% CI, 0.94-1.25; activity: OR, 0.86, 95%CI, 0.75-1.00; enjoyment: OR, 0.85, 95% CI, 0.73-1.00]. Older LTSS consumers living with documented PD are more likely to report not having a case manager; and having a case manager might mitigate PD-associated adverse LTSS outcomes.

接受长期服务和支持(LTSS)的身体残疾(PD)患者经历了更多未满足的服务需求。目前尚不清楚为服务协调设置一个案例管理器是否会修改pd相关的LTSS结果。为了填补这一知识空白,我们评估了PD与急诊科(ED)就诊的关系,以及老年LTSS消费者在有无病例管理人员的情况下的社区整合情况。在6,756名来自2018-2019年国家核心指标-老龄化和残疾调查的受访者(年龄,≥65岁)中,我们评估了三个二分类结果(是或否):ED就诊(超过12个月);自我报告的社区整合包括活动(即在社区中尽可能活跃)和享受(即享受家庭以外的事物)。我们使用逻辑回归,调整消费者的社会人口统计学和健康相关特征,对状态进行随机截距。60%的调查对象有PD记录。PD患者报告没有病例管理人员的可能性要高出27%
{"title":"Physical Disability, Service Coordination, & Outcomes in Publicly-Funded Long-Term Services & Supports.","authors":"Romil Parikh, Dana Urbanski, Chanee Fabius, Stephanie Giordano, Eric Jutkowitz, Tetyana Shippee","doi":"10.1093/geroni/igaf122.013","DOIUrl":"https://doi.org/10.1093/geroni/igaf122.013","url":null,"abstract":"<p><p>People living with physical disability (PD) receiving long-term services & supports (LTSS) experience greater unmet service needs. It is unclear if having a case manager for service coordination modifies PD-associated LTSS outcomes. To fill this knowledge gap, we evaluated associations of PD with emergency department (ED) visits and community integration among older LTSS consumers with and without a case manager. Among 6,756 respondents (age, ≥65 years) from the National Core Indicators- Aging & Disability Survey (2018-2019), we evaluated three dichotomized outcomes (yes vs no): ED visits (over 12 months); and self-reported community integration indicated by both- activity (i.e. being as active in community as preferred) and enjoyment (i.e. enjoying things outside home). We used logistic regression, adjusting for consumers' sociodemographic and health-related characteristics, with random intercept for state. PD was documented in 60% of survey respondents. People living with PD were 27% more likely to report not having a case manager (p < 0.001). Among those without a case manager, PD was associated with significantly greater odds of ED visits (odds ratio [OR], 1.80, 95% CI, 1.48-2.19) and lower odds of community integration [activity: OR, 0.75, 95% CI, 0.62-0.90; enjoyment: OR, 0.69, 95% CI, 0.58-0.83]. These associations were attenuated among consumers with a case manager [ED visits: OR, 1.09, 95% CI, 0.94-1.25; activity: OR, 0.86, 95%CI, 0.75-1.00; enjoyment: OR, 0.85, 95% CI, 0.73-1.00]. Older LTSS consumers living with documented PD are more likely to report not having a case manager; and having a case manager might mitigate PD-associated adverse LTSS outcomes.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 Suppl 2","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12760035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advanced topic modeling with large language models: analyzing social media content from dementia caregivers. 使用大型语言模型的高级主题建模:分析来自痴呆症护理人员的社交媒体内容。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-26 eCollection Date: 2025-12-01 DOI: 10.1093/geroni/igaf120
Weiqing He, Bojian Hou, Amy Zheng, Yanbo Feng, Ari Klein, Karen O'Connor, Shu Yang, Tianqi Shang, George Demiris, Graciela Gonzalez-Hernandez, Li Shen

Background and objectives: While traditional topic modeling methods have been applied to analyze social media content from dementia caregivers, they often struggle with semantic understanding and coherent topic generation. This study explores the direct application of large language models (LLMs) for topic modeling of caregiver tweets, aiming to leverage their advanced semantic comprehension capabilities.

Research design and methods: We analyzed 231 870 tweets from dementia caregivers after preprocessing using ChatGPT as the primary topic modeling tool. To address context length limitations, we developed a 2-stage approach: first splitting the dataset into 226 batches of 1000 tweets each for initial topic extraction, then combining these results through a second-stage prompt for final topic synthesis. We compared our approach against 11 baseline methods, including Latent Dirichlet Allocation (LDA), Gibbs Sampling Dirichlet Multinomial Mixture Model (GSDMM), their term-weighted variants, and state-of-the-art BERTopic models. Topic quality was evaluated using Sentence-BERT-based coherence scores, and topic comprehensiveness was assessed through both ChatGPT and human expert evaluation.

Results: Our LLM-based approach achieved a coherence score of 0.358, significantly outperforming all baseline methods. Traditional approaches like GSDMM (0.317) and LDA (0.320), their term-weighted variants (ranging from 0.264 to 0.302), and BERTopic variants (approximately 0.30) showed lower coherence scores. The 2-stage batching strategy effectively handled the large dataset while maintaining topic quality and representativeness. Expert evaluation confirmed the topics' relevance to caregiver experiences and their comprehensive coverage of key themes.

Discussion and implications: This study introduces a novel methodology for applying LLMs to large-scale topic modeling tasks, demonstrating superior performance over traditional and state-of-the-art approaches. The significant improvement in coherence scores suggests that LLMs can better capture the semantic relationships within topics. Our approach addresses key challenges in context length limitations and prompt engineering, while providing more coherent and interpretable insights into caregiver experiences that can inform targeted support strategies.

背景和目的:虽然传统的主题建模方法已被应用于分析来自痴呆症护理人员的社交媒体内容,但它们往往难以理解语义和连贯的主题生成。本研究探讨了大型语言模型(llm)在护理人员推文主题建模中的直接应用,旨在利用其先进的语义理解能力。研究设计和方法:我们使用ChatGPT作为主要主题建模工具,对来自痴呆症护理人员的231 870条推文进行预处理。为了解决上下文长度的限制,我们开发了一个两阶段的方法:首先将数据集分成226批,每批1000条推文用于初始主题提取,然后通过第二阶段的提示将这些结果组合起来,以进行最终的主题合成。我们将我们的方法与11种基线方法进行了比较,包括潜在狄利克雷分配(LDA)、吉布斯抽样狄利克雷多项混合模型(GSDMM)、它们的术语加权变体和最先进的BERTopic模型。使用基于句子bert的连贯分数来评估主题质量,通过ChatGPT和人类专家评估来评估主题的综合性。结果:我们基于llm的方法获得了0.358的一致性评分,显著优于所有基线方法。传统方法如GSDMM(0.317)和LDA(0.320),它们的术语加权变体(范围从0.264到0.302)和BERTopic变体(约0.30)显示出较低的一致性得分。两阶段批处理策略在保持主题质量和代表性的同时,有效地处理了大型数据集。专家评估证实了这些主题与护理人员经验的相关性及其对关键主题的全面覆盖。讨论和启示:本研究介绍了一种将法学硕士应用于大规模主题建模任务的新方法,展示了优于传统和最先进方法的性能。连贯性得分的显著提高表明llm可以更好地捕捉主题内的语义关系。我们的方法解决了上下文长度限制和快速工程方面的关键挑战,同时为护理人员的体验提供了更连贯和可解释的见解,可以为有针对性的支持策略提供信息。
{"title":"Advanced topic modeling with large language models: analyzing social media content from dementia caregivers.","authors":"Weiqing He, Bojian Hou, Amy Zheng, Yanbo Feng, Ari Klein, Karen O'Connor, Shu Yang, Tianqi Shang, George Demiris, Graciela Gonzalez-Hernandez, Li Shen","doi":"10.1093/geroni/igaf120","DOIUrl":"10.1093/geroni/igaf120","url":null,"abstract":"<p><strong>Background and objectives: </strong>While traditional topic modeling methods have been applied to analyze social media content from dementia caregivers, they often struggle with semantic understanding and coherent topic generation. This study explores the direct application of large language models (LLMs) for topic modeling of caregiver tweets, aiming to leverage their advanced semantic comprehension capabilities.</p><p><strong>Research design and methods: </strong>We analyzed 231 870 tweets from dementia caregivers after preprocessing using ChatGPT as the primary topic modeling tool. To address context length limitations, we developed a 2-stage approach: first splitting the dataset into 226 batches of 1000 tweets each for initial topic extraction, then combining these results through a second-stage prompt for final topic synthesis. We compared our approach against 11 baseline methods, including Latent Dirichlet Allocation (LDA), Gibbs Sampling Dirichlet Multinomial Mixture Model (GSDMM), their term-weighted variants, and state-of-the-art BERTopic models. Topic quality was evaluated using Sentence-BERT-based coherence scores, and topic comprehensiveness was assessed through both ChatGPT and human expert evaluation.</p><p><strong>Results: </strong>Our LLM-based approach achieved a coherence score of 0.358, significantly outperforming all baseline methods. Traditional approaches like GSDMM (0.317) and LDA (0.320), their term-weighted variants (ranging from 0.264 to 0.302), and BERTopic variants (approximately 0.30) showed lower coherence scores. The 2-stage batching strategy effectively handled the large dataset while maintaining topic quality and representativeness. Expert evaluation confirmed the topics' relevance to caregiver experiences and their comprehensive coverage of key themes.</p><p><strong>Discussion and implications: </strong>This study introduces a novel methodology for applying LLMs to large-scale topic modeling tasks, demonstrating superior performance over traditional and state-of-the-art approaches. The significant improvement in coherence scores suggests that LLMs can better capture the semantic relationships within topics. Our approach addresses key challenges in context length limitations and prompt engineering, while providing more coherent and interpretable insights into caregiver experiences that can inform targeted support strategies.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 Suppl 1","pages":"S38-S47"},"PeriodicalIF":4.3,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12742845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145850044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Motivations for participation in nonprofit homeshare programs in the United States: a qualitative study with older home providers and home seekers. 参与美国非营利性房屋共享计划的动机:一项对老年房屋提供者和房屋寻求者的定性研究。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-23 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf141
Susanna R Curry, Molly Calhoun, Angela K Perone, Leyi Zhou, Elizabeth Xanders Pinkis

Background and objectives: Homesharing provides a strategy for addressing housing insecurity by pairing home providers, often older adults, with an extra room in their house with home seekers needing housing. Despite 5 decades of use, research on this intervention remains limited. This study aims to build on this sparse scholarship to provide insight into the motivations for participating as either home seekers or home providers.

Research design and methods: This community-engaged qualitative project includes data from 24 in-depth interviews and short demographic surveys with a diverse group of home providers (n = 13) and home seekers (n = 11) recruited from 2 nonprofit homesharing organizations. Interviews were recorded and professionally transcribed. The researchers used constant comparison techniques to identify patterns and unique perspectives in the transcripts.

Results: Home providers and home seekers had a mean age of 67.92 (SD = 9.39) and 52.09 (SD = 19.03), respectively and were racially/ethnically diverse. The overall sample was primarily female (71%), though more home providers were female (85%) than home seekers (55%). Participants described a range of motivations for participating in homesharing, including financial motivations, the desire for companionship, the result of a disaster or life change, the desire for a task exchange arrangement, the need for administrative/third-party support for housing (including a need for safety and security), and altruistic reasons.

Discussion and implications: This article provides important new data in a vastly understudied area that can inform policy and practice to support affordable housing options for older adults-particularly through nonprofit homesharing programs.

背景和目标:家庭共享提供了一种解决住房不安全问题的策略,通过将家庭提供者(通常是老年人)与需要住房的寻求者配对,在他们的房子里有多余的房间。尽管使用了50年,但对这种干预措施的研究仍然有限。本研究的目的是建立在这个稀疏的奖学金,以提供洞察参与的动机,无论是寻求家庭或家庭提供者。研究设计和方法:这个社区参与的定性项目包括24个深度访谈和简短的人口调查数据,调查对象是来自2个非营利性家庭共享组织的不同群体的家庭提供者(n = 13)和家庭寻求者(n = 11)。采访被记录下来,并由专业人员转录。研究人员经常使用比较技术来识别转录本中的模式和独特视角。结果:家庭提供者和家庭寻求者的平均年龄分别为67.92岁(SD = 9.39)和52.09岁(SD = 19.03),种族/民族多样化。整体样本主要是女性(71%),尽管女性提供家庭服务(85%)多于寻求家庭服务(55%)。参与者描述了参与家庭共享的一系列动机,包括经济动机、对陪伴的渴望、灾难或生活变化的结果、对任务交换安排的渴望、对住房管理/第三方支持的需求(包括对安全和保障的需求)以及利他主义的原因。讨论和启示:这篇文章在一个广泛未被充分研究的领域提供了重要的新数据,可以为政策和实践提供信息,以支持老年人负担得起的住房选择——特别是通过非营利性的住房共享项目。
{"title":"Motivations for participation in nonprofit homeshare programs in the United States: a qualitative study with older home providers and home seekers.","authors":"Susanna R Curry, Molly Calhoun, Angela K Perone, Leyi Zhou, Elizabeth Xanders Pinkis","doi":"10.1093/geroni/igaf141","DOIUrl":"10.1093/geroni/igaf141","url":null,"abstract":"<p><strong>Background and objectives: </strong>Homesharing provides a strategy for addressing housing insecurity by pairing home providers, often older adults, with an extra room in their house with home seekers needing housing. Despite 5 decades of use, research on this intervention remains limited. This study aims to build on this sparse scholarship to provide insight into the motivations for participating as either home seekers or home providers.</p><p><strong>Research design and methods: </strong>This community-engaged qualitative project includes data from 24 in-depth interviews and short demographic surveys with a diverse group of home providers (<i>n </i>= 13) and home seekers (<i>n </i>= 11) recruited from 2 nonprofit homesharing organizations. Interviews were recorded and professionally transcribed. The researchers used constant comparison techniques to identify patterns and unique perspectives in the transcripts.</p><p><strong>Results: </strong>Home providers and home seekers had a mean age of 67.92 (<i>SD</i> = 9.39) and 52.09 (<i>SD</i> = 19.03), respectively and were racially/ethnically diverse. The overall sample was primarily female (71%), though more home providers were female (85%) than home seekers (55%). Participants described a range of motivations for participating in homesharing, including financial motivations, the desire for companionship, the result of a disaster or life change, the desire for a task exchange arrangement, the need for administrative/third-party support for housing (including a need for safety and security), and altruistic reasons.</p><p><strong>Discussion and implications: </strong>This article provides important new data in a vastly understudied area that can inform policy and practice to support affordable housing options for older adults-particularly through nonprofit homesharing programs.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 2","pages":"igaf141"},"PeriodicalIF":4.3,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12863404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Middle-age healthcare spending and utilization at the intersection of comorbidities, functional limitation, and race/ethnicity. 在合并症、功能限制和种族/民族的交叉点中年人医疗保健支出和利用
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-16 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf138
Mohammad Usama Toseef, Shanmin Sultana, Preethy Samuel, Wassim Tarraf

Background and objectives: Middle age is a pivotal developmental life stage marked by health transitions, including the onset of major chronic diseases and functional limitations. Social determinants of health, particularly race/ethnicity, can play a significant role in accentuating the effects of comorbidity and functional limitations. This study examines how comorbidity, functional limitations, and race/ethnicity influence patterns of health services use and spending among middle-aged adults.

Research design and methods: We used pooled yearly cross-sectional data (Medical Expenditure Panel Survey, 2008-2022; excluding 2020) from middle-aged adults (ages 50-64). We derived comorbidity phenotypes using latent class analyses (LCA) and generalized linear regression to examine their associations with health services outcomes, considering the vulnerabilities introduced by functional limitations and race/ethnicity.

Results: LCA supported a 3-class solution: low prevalence of chronic conditions (63.4%), hypertensive/arthritis/joint pain (29.3%), and complex cardiovascular (C-CVD, 7.3%). Individuals with C-CVD had elevated levels of healthcare spending and use, including problematically high levels of emergency department and inpatient hospitalizations, despite higher use of office-based visits (OBVs). We found that Non-Hispanic Black adults (NHBs) and Hispanic adults had lower health spending compared to Non-Hispanic White adults (NHWs) and were less likely to use OBVs. NHBs had a higher propensity for ED use, whereas Hispanic adults were less likely to be hospitalized. Physical and instrumental/activities of daily living (I/ADL) limitations increased OBVs for both NHBs and NHWs, while I/ADLs increased hospitalizations among Hispanic adults.

Discussion and implications: These findings underscore the importance of targeted healthcare for high-risk patient populations for mitigating excess health burdens.

背景和目的:中年是生命发展的关键阶段,以健康转变为标志,包括主要慢性疾病的发病和功能限制。健康的社会决定因素,特别是种族/民族,在加重合并症和功能限制的影响方面可发挥重要作用。本研究探讨了合并症、功能限制和种族/民族如何影响中年人的卫生服务使用和支出模式。研究设计和方法:我们使用汇总的中年人(50-64岁)年度横断面数据(医疗支出小组调查,2008-2022年;不包括2020年)。考虑到功能限制和种族/民族引入的脆弱性,我们使用潜在分类分析(LCA)和广义线性回归推导出共病表型,以检查其与卫生服务结果的关联。结果:LCA支持3类解决方案:低患病率慢性疾病(63.4%),高血压/关节炎/关节疼痛(29.3%)和复杂心血管疾病(C-CVD, 7.3%)。C-CVD患者的医疗支出和使用水平较高,包括急诊科和住院患者的问题高水平,尽管使用更高的办公室就诊(obv)。我们发现,与非西班牙裔白人成年人相比,非西班牙裔黑人成年人(NHBs)和西班牙裔成年人的医疗支出较低,并且不太可能使用obv。非裔美国人使用ED的倾向较高,而西班牙裔成年人住院的可能性较低。身体和工具/日常生活活动(I/ADL)限制增加了nhb和nhw的obv,而I/ADL增加了西班牙裔成年人的住院率。讨论和启示:这些发现强调了针对高危患者群体的针对性医疗对于减轻过度健康负担的重要性。
{"title":"Middle-age healthcare spending and utilization at the intersection of comorbidities, functional limitation, and race/ethnicity.","authors":"Mohammad Usama Toseef, Shanmin Sultana, Preethy Samuel, Wassim Tarraf","doi":"10.1093/geroni/igaf138","DOIUrl":"https://doi.org/10.1093/geroni/igaf138","url":null,"abstract":"<p><strong>Background and objectives: </strong>Middle age is a pivotal developmental life stage marked by health transitions, including the onset of major chronic diseases and functional limitations. Social determinants of health, particularly race/ethnicity, can play a significant role in accentuating the effects of comorbidity and functional limitations. This study examines how comorbidity, functional limitations, and race/ethnicity influence patterns of health services use and spending among middle-aged adults.</p><p><strong>Research design and methods: </strong>We used pooled yearly cross-sectional data (Medical Expenditure Panel Survey, 2008-2022; excluding 2020) from middle-aged adults (ages 50-64). We derived comorbidity phenotypes using latent class analyses (LCA) and generalized linear regression to examine their associations with health services outcomes, considering the vulnerabilities introduced by functional limitations and race/ethnicity.</p><p><strong>Results: </strong>LCA supported a 3-class solution: low prevalence of chronic conditions (63.4%), hypertensive/arthritis/joint pain (29.3%), and complex cardiovascular (C-CVD, 7.3%). Individuals with C-CVD had elevated levels of healthcare spending and use, including problematically high levels of emergency department and inpatient hospitalizations, despite higher use of office-based visits (OBVs). We found that Non-Hispanic Black adults (NHBs) and Hispanic adults had lower health spending compared to Non-Hispanic White adults (NHWs) and were less likely to use OBVs. NHBs had a higher propensity for ED use, whereas Hispanic adults were less likely to be hospitalized. Physical and instrumental/activities of daily living (I/ADL) limitations increased OBVs for both NHBs and NHWs, while I/ADLs increased hospitalizations among Hispanic adults.</p><p><strong>Discussion and implications: </strong>These findings underscore the importance of targeted healthcare for high-risk patient populations for mitigating excess health burdens.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 3","pages":"igaf138"},"PeriodicalIF":4.3,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12915413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Noise during cognitive tests and older adults' cognitive performance: evidence from India. 认知测试中的噪音与老年人的认知表现:来自印度的证据。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-16 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf148
Yezhen Li, Clarice Myers, Wuyang Zhang, Jinkook Lee, Nicholas S Reed, Emma Nichols

Background and objectives: Noise during cognitive assessments may impact cognitive performance and lead to biases in estimates of dementia prevalence, especially in developing regions where optimal test conditions may be harder to ensure. However, evidence on noise during testing and older adults' cognitive performance remains limited. To fill this gap, this study aimed to analyze the role of noise during cognitive assessments in older adults' cognitive scores, using data from a population-based study in India.

Research design and methods: Using data from the second wave of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (n = 3,509), we examined the associations between noise during testing and cognitive scores, and whether these associations varied by respondents' hearing ability.

Results: Noise during testing was significantly associated with lower scores of general cognitive performance and individual cognitive domains. The association between loud noise exposure and cognitive performance was stronger for respondents with normal hearing range and severe hearing loss.

Discussion and implications: Noise during assessments may contribute to biases in cognitive performance in population-based surveys. Further research is needed to better understand the implications of noise during cognitive tests.

背景和目的:认知评估过程中的噪音可能会影响认知表现,并导致对痴呆症患病率的估计存在偏差,特别是在难以确保最佳测试条件的发展中地区。然而,测试过程中的噪音和老年人认知表现之间的关系仍然有限。为了填补这一空白,本研究旨在分析噪音在认知评估中对老年人认知评分的作用,使用的数据来自印度一项基于人口的研究。研究设计和方法:使用印度纵向老龄化研究第二波痴呆诊断评估(n = 3,509)的数据,我们检查了测试过程中的噪音与认知评分之间的关系,以及这些关系是否因受访者的听力能力而变化。结果:测试过程中的噪音与一般认知表现和个体认知领域的较低分数显著相关。在听力正常和听力损失严重的受访者中,大噪音暴露与认知表现之间的关联更强。讨论与启示:在基于人群的调查中,评估过程中的噪音可能会导致认知表现的偏差。为了更好地理解认知测试中噪音的影响,还需要进一步的研究。
{"title":"Noise during cognitive tests and older adults' cognitive performance: evidence from India.","authors":"Yezhen Li, Clarice Myers, Wuyang Zhang, Jinkook Lee, Nicholas S Reed, Emma Nichols","doi":"10.1093/geroni/igaf148","DOIUrl":"10.1093/geroni/igaf148","url":null,"abstract":"<p><strong>Background and objectives: </strong>Noise during cognitive assessments may impact cognitive performance and lead to biases in estimates of dementia prevalence, especially in developing regions where optimal test conditions may be harder to ensure. However, evidence on noise during testing and older adults' cognitive performance remains limited. To fill this gap, this study aimed to analyze the role of noise during cognitive assessments in older adults' cognitive scores, using data from a population-based study in India.</p><p><strong>Research design and methods: </strong>Using data from the second wave of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (<i>n </i>= 3,509), we examined the associations between noise during testing and cognitive scores, and whether these associations varied by respondents' hearing ability.</p><p><strong>Results: </strong>Noise during testing was significantly associated with lower scores of general cognitive performance and individual cognitive domains. The association between loud noise exposure and cognitive performance was stronger for respondents with normal hearing range and severe hearing loss.</p><p><strong>Discussion and implications: </strong>Noise during assessments may contribute to biases in cognitive performance in population-based surveys. Further research is needed to better understand the implications of noise during cognitive tests.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 1","pages":"igaf148"},"PeriodicalIF":4.3,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12832946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146062681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of living arrangements in disability assistance and survival in Mexican older adults. 生活安排在残疾援助和墨西哥老年人生存中的作用。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-15 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf147
Jose Eduardo Cabrero-Castro, Octavio Bramajo, Mariana Calderón-Jaramillo, Philip Cantu, Brian Downer

Background and objectives: This study estimates life expectancy with basic activities of daily living (ADL) and instrumental ADL (IADL) limitations by living arrangements at age 60 for Mexican adults, using the Mexican Health and Aging Study (MHAS) data from 2012 to 2021. We extend previous research by examining assistance with ADL and IADL as a measure of disability severity and exploring the association of disability assistance and mortality.

Research design and methods: Generalized estimating equations were used to examine the relationship between receiving help and living arrangements (living alone, with spouse only, or in extended households). Cox proportional hazards regression assessed the effect of receiving help on mortality. Multistate life table models were used to estimate life expectancy with and without help for ADL and IADL limitations, by gender and living arrangements.

Results: At age 60, those living alone spent a larger share of post-disability life without receiving assistance (ADL: 68.1%; IADL: 19.9%) than those living with others (ADL: 61.6%; IADL: 15.8%). Compared with co-residers, older adults living alone had higher odds of not receiving help with ADL and IADL. Individuals receiving help had higher mortality (ADL hazard ratio [HR] = 1.57; IADL HR = 1.62), consistent with help being a marker of greater severity, not a causal effect.

Discussion and implications: Extended households enable individuals with disabilities to receive assistance for a longer period. Disability assistance was associated with increased mortality risk, highlighting its role as an indirect measure of disability severity.

背景和目的:本研究使用墨西哥健康与老龄化研究(MHAS) 2012年至2021年的数据,通过生活安排估计60岁墨西哥成年人的基本日常生活活动(ADL)和工具性ADL (IADL)限制的预期寿命。我们扩展了先前的研究,将ADL和IADL作为残疾严重程度的衡量标准,并探索残疾援助与死亡率的关系。研究设计和方法:使用广义估计方程来检验接受帮助与生活安排(独居、仅与配偶生活或在大家庭中生活)之间的关系。Cox比例风险回归评估了接受帮助对死亡率的影响。使用多状态生命表模型,按性别和生活安排估计有和没有ADL和IADL限制帮助的预期寿命。结果:60岁时,独居者在失能后无辅助生活中所占比例(ADL: 68.1%; IADL: 19.9%)高于与他人同住者(ADL: 61.6%; IADL: 15.8%)。与共同居民相比,独居的老年人在ADL和IADL方面得不到帮助的几率更高。接受帮助的个体死亡率更高(ADL风险比[HR] = 1.57; IADL风险比[HR] = 1.62),这与帮助是更严重的标志而不是因果关系相一致。讨论和影响:大家庭使残疾人能够在更长的时间内获得援助。残疾援助与死亡风险增加有关,突出了其作为残疾严重程度的间接衡量标准的作用。
{"title":"The role of living arrangements in disability assistance and survival in Mexican older adults.","authors":"Jose Eduardo Cabrero-Castro, Octavio Bramajo, Mariana Calderón-Jaramillo, Philip Cantu, Brian Downer","doi":"10.1093/geroni/igaf147","DOIUrl":"10.1093/geroni/igaf147","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study estimates life expectancy with basic activities of daily living (ADL) and instrumental ADL (IADL) limitations by living arrangements at age 60 for Mexican adults, using the Mexican Health and Aging Study (MHAS) data from 2012 to 2021. We extend previous research by examining assistance with ADL and IADL as a measure of disability severity and exploring the association of disability assistance and mortality.</p><p><strong>Research design and methods: </strong>Generalized estimating equations were used to examine the relationship between receiving help and living arrangements (living alone, with spouse only, or in extended households). Cox proportional hazards regression assessed the effect of receiving help on mortality. Multistate life table models were used to estimate life expectancy with and without help for ADL and IADL limitations, by gender and living arrangements.</p><p><strong>Results: </strong>At age 60, those living alone spent a larger share of post-disability life without receiving assistance (ADL: 68.1%; IADL: 19.9%) than those living with others (ADL: 61.6%; IADL: 15.8%). Compared with co-residers, older adults living alone had higher odds of not receiving help with ADL and IADL. Individuals receiving help had higher mortality (ADL hazard ratio [HR] = 1.57; IADL HR = 1.62), consistent with help being a marker of greater severity, not a causal effect.</p><p><strong>Discussion and implications: </strong>Extended households enable individuals with disabilities to receive assistance for a longer period. Disability assistance was associated with increased mortality risk, highlighting its role as an indirect measure of disability severity.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 1","pages":"igaf147"},"PeriodicalIF":4.3,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12832939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146062311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing empathy and attitudes toward dementia among formal caregivers through virtual reality: a randomized controlled trial. 通过虚拟现实增强正规护理人员对痴呆症的同理心和态度:一项随机对照试验。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-15 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf145
Dorothy Bai, Huei Ling Chiu, Shu-Cheng Lin, Kelvin Tan Cheng Kian, Yeh-Liang Hsu, Gong-Hong Lin

Background and objectives: Enhancing empathy and attitudes among formal caregivers is essential for improving dementia care quality. However, traditional educational approaches often lack the emotional depth needed to foster person-centered care. The primary objective was to evaluate whether an immersive virtual reality (VR) intervention produced greater improvements than a traditional lecture-based education program in empathy and dementia attitudes; secondary outcomes were caregiver burden and psychological distress.

Research design and methods: This parallel-group randomized controlled trial involved 160 formal caregivers randomly assigned to an immersive VR intervention or a time-matched lecture-based comparator. The intervention was delivered as a single 3-hr session comprising three consecutive VR segments, each followed by guided small-group reflection, with brief breaks between segments. Outcomes were measured at baseline, post-intervention, and at 1 month. Analyses followed the intention-to-treat principle using generalized estimating equations.

Results: The VR intervention group exhibited greater improvements in empathy (2.21, 95% CI: 0.42-4.01, p = .016) and attitudes toward dementia (1.18, 95% CI: 0.18-2.17, p = .021) immediately post-intervention compared to the control group. However, these effects were not sustained at the 1-month follow-up.

Discussion and implications: A single-session, multi-segment VR program can produce immediate improvements in empathy and attitudes toward dementia compared with lecture-based education. As effects were not maintained at 1 month, implementation may pair modular VR with low-burden refreshers to support durability while maintaining feasibility. Future research should compare delivery schedules and assess longer-term and behavioral outcomes.

Clinical trial registration: NCT06072274.

背景和目的:增强正式照护者的同理心和态度对于提高痴呆症照护质量至关重要。然而,传统的教育方法往往缺乏培养以人为本的关怀所需的情感深度。主要目的是评估沉浸式虚拟现实(VR)干预是否比传统的基于讲座的教育计划在移情和痴呆症态度方面产生了更大的改善;次要结局为照顾者负担和心理困扰。研究设计和方法:这项平行组随机对照试验涉及160名正式护理人员,随机分配到沉浸式VR干预组或时间匹配的讲座比较组。干预是作为一个3小时的会议进行的,包括三个连续的VR部分,每个部分都有指导的小组反思,部分之间有短暂的休息。在基线、干预后和1个月时测量结果。分析遵循意图处理原则,使用广义估计方程。结果:与对照组相比,VR干预组在干预后立即表现出更大的共情(2.21,95% CI: 0.42-4.01, p = 0.016)和对痴呆症的态度(1.18,95% CI: 0.18-2.17, p = 0.021)的改善。然而,在1个月的随访中,这些效果并没有持续。讨论和影响:与基于讲座的教育相比,单次、多段的VR项目可以立即改善对痴呆症的移情和态度。由于效果在1个月后无法维持,因此可以将模块化VR与低负荷刷新器配对,以支持耐久性,同时保持可行性。未来的研究应该比较分娩时间表,并评估长期和行为结果。临床试验注册:NCT06072274。
{"title":"Enhancing empathy and attitudes toward dementia among formal caregivers through virtual reality: a randomized controlled trial.","authors":"Dorothy Bai, Huei Ling Chiu, Shu-Cheng Lin, Kelvin Tan Cheng Kian, Yeh-Liang Hsu, Gong-Hong Lin","doi":"10.1093/geroni/igaf145","DOIUrl":"https://doi.org/10.1093/geroni/igaf145","url":null,"abstract":"<p><strong>Background and objectives: </strong>Enhancing empathy and attitudes among formal caregivers is essential for improving dementia care quality. However, traditional educational approaches often lack the emotional depth needed to foster person-centered care. The primary objective was to evaluate whether an immersive virtual reality (VR) intervention produced greater improvements than a traditional lecture-based education program in empathy and dementia attitudes; secondary outcomes were caregiver burden and psychological distress.</p><p><strong>Research design and methods: </strong>This parallel-group randomized controlled trial involved 160 formal caregivers randomly assigned to an immersive VR intervention or a time-matched lecture-based comparator. The intervention was delivered as a single 3-hr session comprising three consecutive VR segments, each followed by guided small-group reflection, with brief breaks between segments. Outcomes were measured at baseline, post-intervention, and at 1 month. Analyses followed the intention-to-treat principle using generalized estimating equations.</p><p><strong>Results: </strong>The VR intervention group exhibited greater improvements in empathy (2.21, 95% CI: 0.42-4.01, <i>p</i> = .016) and attitudes toward dementia (1.18, 95% CI: 0.18-2.17, <i>p</i> = .021) immediately post-intervention compared to the control group. However, these effects were not sustained at the 1-month follow-up.</p><p><strong>Discussion and implications: </strong>A single-session, multi-segment VR program can produce immediate improvements in empathy and attitudes toward dementia compared with lecture-based education. As effects were not maintained at 1 month, implementation may pair modular VR with low-burden refreshers to support durability while maintaining feasibility. Future research should compare delivery schedules and assess longer-term and behavioral outcomes.</p><p><strong>Clinical trial registration: </strong>NCT06072274.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 4","pages":"igaf145"},"PeriodicalIF":4.3,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13006054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147503831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between education and awareness of government services among older adults: an integrated approach to examine the role of digital technology use. 老年人的教育与政府服务意识之间的联系:一种综合方法来研究数字技术使用的作用。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-15 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf146
Min-Ah Lee

Background and objectives: Despite the growing importance of digital technology for awareness of and access to government services, and the persistent digital divide by education, few studies have investigated the associations among education, digital technology use, and awareness of government services among older adults. This study examined whether and how digital technology use mediates and moderates the relationship between education and service awareness.

Research design and methods: Data were obtained from the 2023 National Survey of Older Koreans, a nationally representative survey. Multiple regression analyses were conducted to examine the associations among education, digital technology use, and awareness of government services, and to assess the moderating effect of digital technology use. Bootstrapping was used to examine the mediating effect of digital technology use.

Results: Digital technology use partially mediated the relationship between education and service awareness. Lower educational levels were associated with reduced technology use, which was linked to lower awareness. Digital technology use also had a significant moderating effect. Older adults with lower education and limited digital technology use were the most disadvantaged in terms of service awareness. However, their awareness increased substantially with greater digital technology use, showing a steeper improvement than that of higher-educated counterparts.

Discussion and implications: A lack of digital technology use may amplify the negative impact of lower education on service awareness. However, less-educated older adults may achieve greater awareness if their digital technology use is high. Promoting digital skills among those with lower education may be crucial for addressing inequalities in service awareness.

背景和目标:尽管数字技术对政府服务的认识和获取越来越重要,而且教育方面持续存在数字鸿沟,但很少有研究调查老年人教育、数字技术使用和政府服务意识之间的关系。本研究考察了数字技术的使用是否以及如何中介和调节教育与服务意识之间的关系。研究设计和方法:数据来源于具有全国代表性的“2023年全国老年人调查”。本研究采用多元回归分析来检验教育、数字技术使用和政府服务意识之间的关系,并评估数字技术使用的调节作用。采用自举法检验数字技术使用的中介效应。结果:数字技术使用部分中介教育与服务意识之间的关系。较低的教育水平与较少的技术使用有关,这与较低的意识有关。数字技术的使用也有显著的调节作用。受教育程度较低和数字技术使用有限的老年人在服务意识方面处于最不利地位。然而,随着数字技术的使用,他们的意识大大提高,比受过高等教育的同行表现出更大的进步。讨论与启示:缺乏数字技术的使用可能会放大低教育对服务意识的负面影响。然而,如果受教育程度较低的老年人的数字技术使用率很高,他们可能会提高意识。在受教育程度较低的人群中推广数字技能,可能是解决服务意识不平等问题的关键。
{"title":"Associations between education and awareness of government services among older adults: an integrated approach to examine the role of digital technology use.","authors":"Min-Ah Lee","doi":"10.1093/geroni/igaf146","DOIUrl":"10.1093/geroni/igaf146","url":null,"abstract":"<p><strong>Background and objectives: </strong>Despite the growing importance of digital technology for awareness of and access to government services, and the persistent digital divide by education, few studies have investigated the associations among education, digital technology use, and awareness of government services among older adults. This study examined whether and how digital technology use mediates and moderates the relationship between education and service awareness.</p><p><strong>Research design and methods: </strong>Data were obtained from the 2023 National Survey of Older Koreans, a nationally representative survey. Multiple regression analyses were conducted to examine the associations among education, digital technology use, and awareness of government services, and to assess the moderating effect of digital technology use. Bootstrapping was used to examine the mediating effect of digital technology use.</p><p><strong>Results: </strong>Digital technology use partially mediated the relationship between education and service awareness. Lower educational levels were associated with reduced technology use, which was linked to lower awareness. Digital technology use also had a significant moderating effect. Older adults with lower education and limited digital technology use were the most disadvantaged in terms of service awareness. However, their awareness increased substantially with greater digital technology use, showing a steeper improvement than that of higher-educated counterparts.</p><p><strong>Discussion and implications: </strong>A lack of digital technology use may amplify the negative impact of lower education on service awareness. However, less-educated older adults may achieve greater awareness if their digital technology use is high. Promoting digital skills among those with lower education may be crucial for addressing inequalities in service awareness.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 4","pages":"igaf146"},"PeriodicalIF":4.3,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12995426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of intrinsic capacity and neighborhood environment with dementia risk: an interaction and mediation analysis. 内在能力和邻里环境与痴呆风险的关联:相互作用和中介分析。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-13 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf135
Shuanglong Hou, Jing Luo, Rui Liu, Xueqiang Wang

Background and objectives: While intrinsic capacity (IC) impairment and adverse neighborhood environments are established independent risk factors for dementia, their interaction effects and potential mediating pathways remain poorly understood. This study aimed to examine the independent, interactive, and mediating associations of IC, neighborhood environment, and dementia risk among middle-aged and older adults.

Research design and methods: We analyzed data from 8,107 adults aged 50+ in the China Health and Retirement Longitudinal Study (2011-2020). IC was quantified using a composite impairment score encompassing locomotor, cognitive, sensory, psychological, and vitality domains. Neighborhood environment was classified by resource availability and social provisions (low risk; moderate risk; high risk). Cox proportional hazards models evaluated associations between IC, neighborhood environment, and dementia risk. The four-way decomposition model was used to examine the potential interaction and mediation effects of IC.

Results: Over a median follow-up of 9 years, 909 incident dementia cases occurred. Adjusted analyses revealed dose-dependent relationships: each 1-point increase in IC impairment score elevated dementia risk by 26% (hazard ratio [HR] = 1.29, 95% confidence interval [CI]: 1.22-1.36). Compared with low-risk neighborhoods, moderate-risk (HR = 1.26, 95% CI: 1.08-1.47), and high-risk neighborhoods (HR = 1.41, 95% CI: 1.13-1.77) independently increased dementia risk. Four-way decomposition revealed the association between adverse neighborhood environments and increased dementia risk was partially explained by the pure mediation effect of IC, with no significant interaction-only/mediated interaction effects observed.

Discussion and implications: IC impairments and adverse neighborhood environments independently escalate dementia risk, with IC partially mediating the environmental effects. Integrating interventions targeting both individual capacity and community-level infrastructure may optimize dementia prevention strategies.

背景和目的:虽然内在能力(IC)损伤和不良的邻里环境是痴呆的独立危险因素,但它们的相互作用和潜在的介导途径仍然知之甚少。本研究旨在探讨IC、邻里环境和中老年人痴呆风险之间的独立、互动和中介关系。研究设计和方法:我们分析了中国健康与退休纵向研究(2011-2020)中8107名50岁以上成年人的数据。使用包括运动、认知、感觉、心理和活力领域的复合损伤评分来量化IC。根据资源可得性和社会条件对社区环境进行分类(低风险、中等风险、高风险)。Cox比例风险模型评估了IC、社区环境和痴呆风险之间的关系。采用四向分解模型检验ic的潜在相互作用和中介作用。结果:在中位随访9年期间,909例痴呆发生。调整后的分析显示了剂量依赖关系:IC损伤评分每增加1分,痴呆风险增加26%(风险比[HR] = 1.29, 95%可信区间[CI]: 1.22-1.36)。与低危社区相比,中度危社区(HR = 1.26, 95% CI: 1.08-1.47)和高危社区(HR = 1.41, 95% CI: 1.13-1.77)分别增加痴呆风险。四向分解表明,不良邻里环境与痴呆风险增加之间的关系部分可以用IC的纯粹中介作用来解释,没有观察到显著的相互作用/中介相互作用。讨论和意义:IC损伤和不利的社区环境独立地增加痴呆风险,IC部分介导环境影响。针对个人能力和社区基础设施的综合干预措施可以优化痴呆症预防策略。
{"title":"Association of intrinsic capacity and neighborhood environment with dementia risk: an interaction and mediation analysis.","authors":"Shuanglong Hou, Jing Luo, Rui Liu, Xueqiang Wang","doi":"10.1093/geroni/igaf135","DOIUrl":"https://doi.org/10.1093/geroni/igaf135","url":null,"abstract":"<p><strong>Background and objectives: </strong>While intrinsic capacity (IC) impairment and adverse neighborhood environments are established independent risk factors for dementia, their interaction effects and potential mediating pathways remain poorly understood. This study aimed to examine the independent, interactive, and mediating associations of IC, neighborhood environment, and dementia risk among middle-aged and older adults.</p><p><strong>Research design and methods: </strong>We analyzed data from 8,107 adults aged 50+ in the China Health and Retirement Longitudinal Study (2011-2020). IC was quantified using a composite impairment score encompassing locomotor, cognitive, sensory, psychological, and vitality domains. Neighborhood environment was classified by resource availability and social provisions (low risk; moderate risk; high risk). Cox proportional hazards models evaluated associations between IC, neighborhood environment, and dementia risk. The four-way decomposition model was used to examine the potential interaction and mediation effects of IC.</p><p><strong>Results: </strong>Over a median follow-up of 9 years, 909 incident dementia cases occurred. Adjusted analyses revealed dose-dependent relationships: each 1-point increase in IC impairment score elevated dementia risk by 26% (hazard ratio [HR] = 1.29, 95% confidence interval [CI]: 1.22-1.36). Compared with low-risk neighborhoods, moderate-risk (HR = 1.26, 95% CI: 1.08-1.47), and high-risk neighborhoods (HR = 1.41, 95% CI: 1.13-1.77) independently increased dementia risk. Four-way decomposition revealed the association between adverse neighborhood environments and increased dementia risk was partially explained by the pure mediation effect of IC, with no significant interaction-only/mediated interaction effects observed.</p><p><strong>Discussion and implications: </strong>IC impairments and adverse neighborhood environments independently escalate dementia risk, with IC partially mediating the environmental effects. Integrating interventions targeting both individual capacity and community-level infrastructure may optimize dementia prevention strategies.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 2","pages":"igaf135"},"PeriodicalIF":4.3,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12907018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Widely used but weakly studied: a research agenda for Memory Cafés. 广泛使用但研究薄弱:记忆卡萨的研究议程。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-13 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf143
Lisa A Juckett, Kali S Thomas, Kimberly P Bernard, Sam Goodrich, Susan McFadden
{"title":"Widely used but weakly studied: a research agenda for Memory Cafés.","authors":"Lisa A Juckett, Kali S Thomas, Kimberly P Bernard, Sam Goodrich, Susan McFadden","doi":"10.1093/geroni/igaf143","DOIUrl":"10.1093/geroni/igaf143","url":null,"abstract":"","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 1","pages":"igaf143"},"PeriodicalIF":4.3,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12812001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Innovation in Aging
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1