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Qualitative research in gerontology: rigor, legacy, and the next wave of innovation. 定性研究在老年学:严谨性,遗产,和创新的下一波。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-13 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf140
Sean N Halpin, Tracie C Harrison, Angie K Perone, Natalie D Pope, Abby J Schwartz
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引用次数: 0
Digital narratives in person-centered care: a scoping review. 以人为本的护理中的数字叙述:范围审查。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-13 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf144
Irene Rodríguez-Trejo, Alba Felpete, David Facal, Raúl Vaca-Bermejo, Cristina Lojo-Seoane

Background and objectives: Narrative care, an essential component of person-centered care (PCC), individualized care that respects unique life stories and preferences, uses personal narratives to foster understanding, trust, and emotional well-being. Digital storytelling has emerged as a valuable tool to collect and preserve these narratives. This scoping review explored digital tools used to capture life stories of older adults, summarizing their benefits, limitations, and implications for PCC.

Research design and methods: Studies addressing digital storytelling, life review, or life story work with older adults, published in English or Spanish, and reporting cognitive, psychological, social, or care-related outcomes were included. A systematic search was conducted in Web of Science, SCOPUS, PubMed, and PsycInfo in December 2024, identifying 615 records. After screening and full-text review, 21 studies were included. Data were extracted on study design, sample characteristics, digital tools, outcomes, and limitations. Digital resources were classified into short or long videos, digital albums/collages, digital books/stories, and other formats.

Results: The review encompassed 1,551 participants (age M = 75.86 years). Digital storytelling improved emotional well-being, preserved personal identity, fostered social connections, and stimulated cognitive functions. Short formats proved particularly suitable when cognitive or digital literacy limitations were present, whereas longer formats supported in-depth reflection and memory preservation. Albums and digital books enhanced intergenerational communication. Key limitations included technological barriers, varying digital literacy levels, and lack of methodological standardization.

Discussion and implications: Digital storytelling enhances PCC by embedding personal narratives into care, but successful implementation requires addressing digital inequalities and standardizing methodologies through interdisciplinary collaboration.

背景和目的:叙事性护理是以人为本的护理(PCC)的重要组成部分,是尊重独特的生活故事和偏好的个性化护理,使用个人叙述来促进理解、信任和情感健康。数字叙事已经成为收集和保存这些叙事的宝贵工具。本综述探讨了用于捕捉老年人生活故事的数字工具,总结了它们的优点、局限性和对PCC的影响。研究设计和方法:纳入以英语或西班牙语发表的关于老年人数字化叙事、生活回顾或生活故事工作的研究,并报告认知、心理、社会或护理相关的结果。系统检索Web of Science、SCOPUS、PubMed、PsycInfo于2024年12月检索到615条记录。经过筛选和全文审查,纳入了21项研究。从研究设计、样本特征、数字工具、结果和局限性等方面提取数据。数字资源分为短视频和长视频、数字相册/拼贴画、数字图书/故事和其他格式。结果:该综述包括1551名参与者(年龄M = 75.86岁)。数字叙事改善了情感健康,保留了个人身份,促进了社会联系,并刺激了认知功能。短格式被证明特别适合存在认知或数字读写能力限制的情况,而长格式则支持深入反思和记忆保存。专辑和电子书加强了代际交流。主要的限制包括技术障碍、不同的数字素养水平和缺乏方法标准化。讨论和影响:数字化叙事通过将个人叙事嵌入到护理中来增强PCC,但成功实施需要解决数字不平等问题,并通过跨学科合作使方法标准化。
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引用次数: 0
Work conditions are associated with physical health in later life: a longitudinal cohort study in Taiwan. 工作条件与晚年身体健康的关系:台湾的一项纵向队列研究。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-13 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf142
Wan-Ju Cheng, Chi-Shin Wu, Chen-Yu Wang, Shau-Huai Fu, Chih-Cheng Hsu, Yun-Chieh Yang

Background and objectives: Work occupies a significant portion of adult life, and work conditions are associated with health among workers. This study examined the association between work conditions and mortality, heart disease, stroke, osteoporosis or osteoporotic fracture, and frailty in later life.

Research design and methods: This study included a cohort of 4,192 community-dwelling adults ≥55 years old. A matrix of work conditions by occupation was constructed using a representative national survey in Taiwan. Psychosocial work conditions were assessed using the Job Content Questionnaire, focusing on job control and psychological demands. Mortality and physical morbidity were identified through physician diagnoses recorded in the National Health Insurance Database.

Results: During 10 years of follow-up, 25.0% of the participants died, and 14.2% were diagnosed with heart disease, 17.6% with stroke, 19.4% with osteoporosis or osteoporotic fractures, and 48.66% with frailty. After adjusting for confounding factors, high-skill-discretion jobs (vs low) were associated with a 0.84-fold hazard of mortality (95% confidence interval [CI]: 0.73-0.97), a 0.60-fold hazard of hemorrhagic stroke (95% CI: 0.40-0.90), a 0.79-fold lower hazard of heart disease (95% CI: 0.64-0.97), and a lower multimorbidity frailty index (95% CI: -7.75 to -2.49). Additionally, high psychological demands (vs low) were associated with a 0.85-fold risk of mortality (95% CI: 0.75-0.97) and osteoporosis or osteoporotic fractures (95% CI: 0.73-0.99).

Discussion and implications: High skill utilization and psychological demands were associated with reduced risks of mortality and morbidity in later life. Decent working conditions constitute a modifiable factor that supports healthy aging.

背景和目标:工作占成年人生活的很大一部分,工作条件与工人的健康有关。这项研究调查了工作条件与死亡率、心脏病、中风、骨质疏松症或骨质疏松性骨折以及晚年虚弱之间的关系。研究设计和方法:本研究纳入4192名≥55岁的社区居住成年人。本研究以台湾一具代表性的全国性调查为基础,建构职业工作条件矩阵。采用《工作内容问卷》评估心理社会工作条件,重点关注工作控制和心理需求。死亡率和身体发病率是通过记录在国家健康保险数据库中的医生诊断确定的。结果:在10年的随访期间,25.0%的参与者死亡,14.2%被诊断患有心脏病,17.6%患有中风,19.4%患有骨质疏松或骨质疏松性骨折,48.66%患有虚弱。在调整混杂因素后,高技能自由裁量的工作(相对于低技能自由裁量的工作)与0.84倍的死亡率(95%置信区间[CI]: 0.73-0.97)、0.60倍的出血性卒中风险(95% CI: 0.40-0.90)、0.79倍的心脏病风险(95% CI: 0.64-0.97)和较低的多病性虚弱指数(95% CI: -7.75至-2.49)相关。此外,高心理需求(相对低)与0.85倍的死亡率(95% CI: 0.75-0.97)和骨质疏松或骨质疏松性骨折(95% CI: 0.73-0.99)相关。讨论和启示:高技能利用率和心理需求与晚年死亡率和发病率的降低相关。体面的工作条件是支持健康老龄化的可改变因素。
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引用次数: 0
Spotlighting the need for integrated health information technologies and databases to combat infections and sepsis in long-term care facilities. 强调需要综合卫生信息技术和数据库,以在长期护理设施中防治感染和败血症。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-10 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf134
Yu Jin Kang, Karen Nielsen, Jingyu Liu
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引用次数: 0
Associations of social isolation and loneliness with healthcare utilization among older adults: a systematic review and meta-analysis. 社会隔离和孤独感与老年人医疗保健利用的关系:系统回顾和荟萃分析
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-10 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf136
Tianxue Hou, Mu-Hsing Ho, Zohar Lederman, Denise Shuk Ting Cheung, Timothy Hudson Rainer, Chia-Chin Lin

Background and objectives: Social isolation and loneliness are significant public health concerns associated with increased healthcare utilization among older adults. This review aims to synthesize evidence on the associations between social isolation, loneliness, and healthcare utilization.

Research design and methods: Five databases were searched from inception to March 21, 2025, using keyword groups related to social isolation/loneliness, older adults, and healthcare utilization (primary care, emergency visits, inpatient care, and outpatient care). Methodological quality was assessed using the Newcastle-Ottawa Scale. Random-effects models were employed to pool effect sizes (incidence rate ratios [IRRs], odds ratios [ORs]).

Results: A total of 44 studies were included in the systematic review, and 34 were included in the meta-analysis (N = 309,023). Due to insufficient data, meta-analyses for the association between social isolation and primary care or outpatient care utilization were not conducted. Social isolation was statistically associated with increased inpatient care utilization (IRRs = 1.37, 95% CI: 1.24-1.53) but not with emergency department visits. For loneliness, meta-analyses for outpatient care were not feasible due to limited studies. Loneliness was statistically associated with increased emergency department visits (IRRs = 1.15, 95% CI: 1.06-1.24) and inpatient care utilization (OR = 1.13, 95% CI: 1.07-1.20) but not with primary care use.

Discussion and implications: This is the first meta-analysis to comprehensively synthesize the associations between social isolation, loneliness, and 4 types of healthcare utilization among older adults. The findings highlight the importance of addressing social isolation and loneliness as potential strategies to reduce avoidable healthcare utilization.

背景和目的:社会隔离和孤独是与老年人医疗保健使用率增加相关的重大公共卫生问题。本综述旨在综合社会隔离、孤独感和医疗保健利用之间关系的证据。研究设计和方法:从研究开始到2025年3月21日,对5个数据库进行检索,使用与社会隔离/孤独、老年人和医疗保健利用(初级保健、急诊、住院和门诊)相关的关键词组。采用纽卡斯尔-渥太华量表评估方法学质量。采用随机效应模型汇总效应大小(发病率比[IRRs],优势比[ORs])。结果:系统评价共纳入44项研究,meta分析纳入34项研究(N = 309023)。由于数据不足,没有对社会隔离与初级保健或门诊保健利用之间的关系进行meta分析。社会隔离在统计学上与住院治疗利用率增加相关(irr = 1.37, 95% CI: 1.24-1.53),但与急诊就诊无关。对于孤独感,由于研究有限,门诊护理的荟萃分析不可行。从统计学上看,孤独感与急诊科就诊次数增加(ir = 1.15, 95% CI: 1.06-1.24)和住院治疗利用(OR = 1.13, 95% CI: 1.07-1.20)相关,但与初级保健使用无关。讨论与启示:这是第一个全面综合老年人社会隔离、孤独感和4种医疗保健利用之间关系的荟萃分析。研究结果强调了解决社会隔离和孤独作为减少可避免的医疗保健利用的潜在策略的重要性。
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引用次数: 0
Self-efficacy as a mediator between dementia knowledge and screening intention among American Indian adults. 自我效能感在美国印第安成人痴呆知识与筛查意愿之间的中介作用。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-12-04 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf131
Heehyul E Moon, Yeon-Shim Lee, Soonhee Roh, Cole Allick, James E Galvin, Sasheen T Stone

Background and objectives: While early detection of Alzheimer's disease and related dementias (ADRD) can help delay progression and improve outcomes, limited research is available on dementia-related health behavior, such as screening intention among American Indian/Alaska Native communities. Guided by the Theory of Reasoned Action, the Theory of Planned Behavior, and the Health Belief Model, this study examines whether self-efficacy mediates the association between dementia knowledge and intention to seek ADRD screening among American Indian adults.

Research design and methods: Using a community-based participatory research approach, a cross-sectional survey was conducted with 248 American Indian adults (18 years and over) from a partner tribal community in the Northern Plains region in 2024. Measures included dementia knowledge, self-efficacy, screening intention, perceived susceptibility, stigma, and demographic factors. Mediation was tested using the Baron and Kenny framework and Sobel-Goodman tests.

Results: Dementia knowledge significantly predicted both ADRD screening intention and self-efficacy. Self-efficacy also significantly predicted screening intention and partially mediated the relationship between knowledge and intention. Approximately 32% of the effect of dementia knowledge on screening intention was mediated by self-efficacy.

Discussion and implications: Findings underscore self-efficacy as a critical mechanism through which dementia knowledge translates into ADRD screening intention in American Indian communities. Interventions to promote early ADRD detection could enhance both knowledge and individual confidence. Future research should include more diverse groups within American Indian communities to identify common and unique dynamics among knowledge, self-efficacy, and screening intention, informing effective intervention strategies to reduce stigma and confidence in seeking timely ADRD screening.

背景和目的:虽然早期发现阿尔茨海默病和相关痴呆(ADRD)可以帮助延缓进展和改善结果,但关于痴呆相关健康行为的研究有限,例如美国印第安人/阿拉斯加土著社区的筛查意向。在理性行为理论、计划行为理论和健康信念模型的指导下,本研究探讨了自我效能感是否在美国印第安成年人的痴呆知识与寻求ADRD筛查意愿之间起中介作用。研究设计和方法:采用基于社区的参与式研究方法,于2024年对北部平原地区一个伙伴部落社区的248名18岁及以上的美国印第安人成年人进行了横断面调查。测量包括痴呆知识、自我效能、筛查意愿、感知易感性、耻辱感和人口统计学因素。使用Baron和Kenny框架和Sobel-Goodman测试对调解进行了测试。结果:痴呆知识对ADRD筛查意愿和自我效能感均有显著预测作用。自我效能感显著预测筛选意向,并部分介导知识与意向的关系。大约32%的痴呆知识对筛查意向的影响是由自我效能介导的。讨论和启示:研究结果强调自我效能是一个关键的机制,通过痴呆知识转化为美国印第安人社区的ADRD筛查意愿。促进ADRD早期发现的干预措施可以增强知识和个人信心。未来的研究应该包括更多不同的美国印第安人社区,以确定知识、自我效能和筛查意图之间的共同和独特的动态,为有效的干预策略提供信息,以减少耻辱感和及时寻求ADRD筛查的信心。
{"title":"Self-efficacy as a mediator between dementia knowledge and screening intention among American Indian adults.","authors":"Heehyul E Moon, Yeon-Shim Lee, Soonhee Roh, Cole Allick, James E Galvin, Sasheen T Stone","doi":"10.1093/geroni/igaf131","DOIUrl":"10.1093/geroni/igaf131","url":null,"abstract":"<p><strong>Background and objectives: </strong>While early detection of Alzheimer's disease and related dementias (ADRD) can help delay progression and improve outcomes, limited research is available on dementia-related health behavior, such as screening intention among American Indian/Alaska Native communities. Guided by the Theory of Reasoned Action, the Theory of Planned Behavior, and the Health Belief Model, this study examines whether self-efficacy mediates the association between dementia knowledge and intention to seek ADRD screening among American Indian adults.</p><p><strong>Research design and methods: </strong>Using a community-based participatory research approach, a cross-sectional survey was conducted with 248 American Indian adults (18 years and over) from a partner tribal community in the Northern Plains region in 2024. Measures included dementia knowledge, self-efficacy, screening intention, perceived susceptibility, stigma, and demographic factors. Mediation was tested using the Baron and Kenny framework and Sobel-Goodman tests.</p><p><strong>Results: </strong>Dementia knowledge significantly predicted both ADRD screening intention and self-efficacy. Self-efficacy also significantly predicted screening intention and partially mediated the relationship between knowledge and intention. Approximately 32% of the effect of dementia knowledge on screening intention was mediated by self-efficacy.</p><p><strong>Discussion and implications: </strong>Findings underscore self-efficacy as a critical mechanism through which dementia knowledge translates into ADRD screening intention in American Indian communities. Interventions to promote early ADRD detection could enhance both knowledge and individual confidence. Future research should include more diverse groups within American Indian communities to identify common and unique dynamics among knowledge, self-efficacy, and screening intention, informing effective intervention strategies to reduce stigma and confidence in seeking timely ADRD screening.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 1","pages":"igaf131"},"PeriodicalIF":4.3,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12782657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying deprescribing profiles in older adults from 14 countries using the Patient Deprescribing Typology. 使用患者处方解除类型学确定来自14个国家的老年人的处方解除概况。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-25 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf130
Kristie Rebecca Weir, Vincent D Marshall, Katharina Tabea Jungo, Renata Vidonscky Lüthold, Zsofia Rozsnyai, Sven Streit, Sarah E Vordenberg

Background and objectives: Categorizing older adults by their medication and deprescribing beliefs may support tailored communication and shared decision-making. We aimed to identify latent classes of patients using the Patient Deprescribing Typology.

Research design and methods: This cross-sectional study used survey responses from 1,131 primary care patients (≥65 years, ≥5 medications) in 14 countries between May 2022 and December 2023. A latent class analysis was conducted using the 4-item Patient Deprescribing Typology, which captures older adults' views on medication importance, learning styles, decision-making preferences, and attitudes toward stopping medications. A multinomial logit model was used to compare the latent classes.

Results: Among the 1,131 participants, 55.2% (n = 624) were female, and on average, participants were taking 7 regular medications (SD = 2.3). Three latent classes were identified: (1) Would consider deprescribing (n = 760, 67.2%), (2) Attached to medications (n = 249, 22.0%), and (3) Defers decision-making to others (n = 122, 10.8%). Compared with participants who Would consider deprescribing, those Attached to medications were significantly less likely to want to deprescribe one of their specific medications (odds ratio [OR] = 0.04, 95% CI: 0.02-0.09, p < .001). Participants who Defer decision-making to others reported lower trust in their GP (OR = 0.47, 95% CI: 0.32-0.67).

Discussion and implications: While most participants expressed openness to deprescribing, their preferences for information sources, perceived medication importance, and decision-making roles varied. Our findings highlight the need to account for patient differences in deprescribing attitudes. Typologies offer a practical basis for personalized communication and patient-centered interventions.

背景和目的:根据老年人的药物和描述信仰对他们进行分类可能有助于有针对性的沟通和共同决策。我们的目的是利用患者处方解除类型学来确定潜在的患者类别。研究设计和方法:这项横断面研究使用了2022年5月至2023年12月期间来自14个国家的1131名初级保健患者(≥65岁,≥5种药物)的调查反馈。使用4项患者处方解除类型进行了潜在类分析,该分析捕获了老年人对药物重要性、学习风格、决策偏好和停药态度的看法。使用多项逻辑模型对潜在类别进行比较。结果:1131名参与者中,女性占55.2% (n = 624),平均服用7种常规药物(SD = 2.3)。确定了三个潜在类别:(1)会考虑开处方(n = 760, 67.2%),(2)依附于药物(n = 249, 22.0%),(3)将决策推迟给他人(n = 122, 10.8%)。与考虑开处方的参与者相比,那些依赖药物的参与者想要开某种特定药物的可能性明显更低(优势比[OR] = 0.04, 95% CI: 0.02-0.09, p)推迟决策给他人的报告对其全科医生的信任度较低(OR = 0.47, 95% CI: 0.32-0.67)。讨论和影响:虽然大多数参与者对处方的描述持开放态度,但他们对信息来源、感知药物重要性和决策角色的偏好各不相同。我们的研究结果强调需要考虑到患者在处方态度上的差异。类型学为个性化沟通和以患者为中心的干预提供了实践基础。
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引用次数: 0
Socially focused intelligent assistive technologies for caregiving for homebound older adults with cognitive impairment: a scoping review. 以社会为中心的智能辅助技术用于照顾有认知障碍的居家老年人:范围综述。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-21 eCollection Date: 2025-01-01 DOI: 10.1093/geroni/igaf117
Juliet Chigozie Donatus Ezulike, Mohit Prashar, Kosisochukwu Anyaegbunam, Blessing Ugochi Ojembe, Shital Desai, Michael Ebe Kalu

Background and objectives: Being homebound with cognitive impairment (CI) presents major public health challenges, increasing home healthcare costs and contributing to caregiver burden, social isolation, and reduced quality of life. As loneliness and social isolation rise among this population, socially focused intelligent assistive technologies (SFIATs) have emerged as increasingly viable solutions. This scoping review examined the current body of literature on SFIATs and the barriers and facilitators to their support of homebound older adults with CI and their caregivers.

Research design and methods: Using Arksey and O'Malley's framework, we searched 12 databases with MeSH terms related to older adults, CI, SFIATs, and homebound status. Data were analyzed descriptively using themes, with findings mapped across the socioecological framework.

Results: Nineteen studies conducted in 12 high-income countries were included. Robots, tablets, telephones, computers, virtual avenues, and other smart devices were among the SFIATs utilized in caregiving for older individuals who were homebound or had CI. SFIATs facilitated social interaction, engagement, and connectedness among older adults and caregivers. Challenges and benefits associated with their use were evident at individual, interpersonal, community, organizational, and policy levels.

Discussion and implications: Research suggests significant potential in SFIATs, but their implementation faces multi-level challenges, often due to limited direct input from end-users, leading to concerns that impact their utilization. SFIAT development must adopt co-creation approaches to ensure its contextual appropriateness. Further research is needed, particularly in low- and middle-income countries, to understand the landscape, benefits, and challenges of SFIATs in diverse global settings.

背景和目的:患有认知障碍(CI)的居家患者带来了重大的公共卫生挑战,增加了家庭医疗保健费用,并造成照顾者负担、社会孤立和生活质量下降。随着孤独感和社会隔离在这一人群中的上升,以社交为重点的智能辅助技术(SFIATs)已成为越来越可行的解决方案。本综述研究了目前关于sfiat的文献,以及支持居家CI老年人及其照护者的障碍和促进因素。研究设计和方法:使用Arksey和O'Malley的框架,我们检索了12个数据库,其中包含与老年人、CI、sfiat和居家状态相关的MeSH术语。使用主题对数据进行描述性分析,并将结果映射到整个社会生态框架中。结果:纳入了在12个高收入国家进行的19项研究。机器人、平板电脑、电话、电脑、虚拟通道和其他智能设备都是用于照顾居家或患有CI的老年人的sfiat。sfiat促进了老年人和照顾者之间的社会互动、参与和联系。在个人、人际、社区、组织和政策层面上,与使用它们相关的挑战和好处是显而易见的。讨论和影响:研究表明SFIATs具有巨大的潜力,但其实施面临多层次的挑战,通常是由于最终用户的直接投入有限,导致影响其利用的担忧。SFIAT的发展必须采用共同创造的方法,以确保其上下文的适当性。需要进一步研究,特别是在低收入和中等收入国家,以了解SFIATs在不同全球环境下的前景、效益和挑战。
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引用次数: 0
Effects of dance training on oxytocin secretion and neural activity in older adults with subjective cognitive decline. 舞蹈训练对主观认知衰退老年人后叶催产素分泌和神经活动的影响。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-14 eCollection Date: 2026-01-01 DOI: 10.1093/geroni/igaf129
Masatoshi Yamashita, Aya Toyoshima, Shoko Iwasaki, Reina Takamatsu, Hiroyuki Muto, Nobuhito Abe, Jin Narumoto, Kaoru Sekiyama

Background and objectives: Subjective cognitive decline (SCD) is a preclinical stage of mild cognitive impairment (MCI). Although dance training has been shown to be beneficial for mental health, cognitive function, and neural activity in older adults with MCI, its effect on SCD remains unclear. This study aimed to examine the effects of dance training on the aforementioned factors and on oxytocin secretion in older adults with SCD.

Research design and methods: Participants (aged 65-84 years) were assigned to either the intervention group (n = 22) with a 12-week dance training program or the control group without any alternative training (n = 22). Apathy, depression, Montreal Cognitive Assessment scores, urinary oxytocin levels, and resting-state functional magnetic resonance imaging indices, including amplitude of low-frequency fluctuations (ALFF) and functional connectivity (FC), were evaluated pre- and post-intervention.

Results: Compared to the control group, the intervention group exhibited significantly higher urinary oxytocin levels and significantly higher ALFF in the left medial orbitofrontal cortex post-intervention. Moreover, the intervention group showed more enhanced FC between the left medial orbitofrontal cortex and the left precuneus post-intervention than the control group. However, mental health or cognitive performance was not significantly different between the groups.

Discussion and implications: Our results are particularly important in light of previous findings that older adults with SCD show a reduced FC between the medial orbitofrontal cortex and the precuneus, and that oxytocin levels are positively associated with the prefrontal-amygdala oxytocinergic circuit in socioemotional processing. Thus, dance training may contribute to socioemotional resilience-related neural and molecular adaptations in SCD.

背景与目的:主观认知衰退(SCD)是轻度认知障碍(MCI)的临床前阶段。尽管舞蹈训练已被证明对老年MCI患者的心理健康、认知功能和神经活动有益,但其对SCD的影响尚不清楚。本研究旨在探讨舞蹈训练对上述因素的影响以及对老年SCD患者催产素分泌的影响。研究设计和方法:参与者(65-84岁)被分为干预组(n = 22)和对照组(n = 22),实验组接受为期12周的舞蹈训练,对照组不接受任何替代训练。在干预前后评估冷漠、抑郁、蒙特利尔认知评估评分、尿后叶催产素水平和静息状态功能磁共振成像指标,包括低频波动幅度(ALFF)和功能连通性(FC)。结果:干预组与对照组相比,干预后尿中催产素水平显著升高,左侧内侧眶额皮质ALFF显著升高。此外,干预组在干预后显示左侧内侧眶额皮质和左侧楔前叶之间的FC比对照组增强。然而,两组之间的心理健康或认知表现没有显著差异。讨论和意义:我们的研究结果特别重要,因为先前的研究结果表明,患有SCD的老年人在内侧眶额叶皮层和楔前叶之间显示出减少的FC,并且催产素水平与前额叶-杏仁核在社会情绪处理中的催产素能回路呈正相关。因此,舞蹈训练可能有助于SCD中与社会情绪弹性相关的神经和分子适应。
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引用次数: 0
Transportation barriers, loneliness, and depressive/anxiety symptoms in older adults. 老年人的交通障碍、孤独和抑郁/焦虑症状。
IF 4.3 3区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-11-12 eCollection Date: 2025-01-01 DOI: 10.1093/geroni/igaf127
Namkee G Choi, C Nathan Marti

Background and objectives: Transportation is crucial to maintaining social engagement in later life. Lack of transportation is significantly associated with depressive/anxiety symptoms in older adults. In this study, we examined the extent to which loneliness mediates the relationship between transportation barriers and depressive/anxiety symptoms.

Research design and methods: Using the 2023 National Health and Aging Trends Study (N = 7,547; age 65+), we defined transportation barriers as transportation problems that kept older adults from visiting family/friends, attending religious services, attending club meetings, or going out for enjoyment. We fitted a path model, and to test the mediation effect, we used bootstrapped analysis to obtain estimates of the indirect effects and their 95% confidence intervals (CIs).

Results: Of the study population, 4.4%, or 2 million people, reported transportation barriers. We found significant direct effects of transportation barriers on loneliness and depressive/anxiety symptoms and indirect effects of loneliness (0.40, 95% CIs = [0.23, 0.57], z = 4.57, p < .001) on depressive/anxiety symptoms. The ratio of the indirect effect to the total effect of transportation barriers on depressive/anxiety symptoms (indirect effect [0.40] + direct effect [0.50] = 0.90) was 0.44. The ratio of the indirect effect of loneliness to the direct effect of transportation barriers on depressive/anxiety symptoms was 0.80.

Discussion and implications: Loneliness significantly mediates the association between transportation barriers and depression/anxiety in older adults. Transportation should be recognized as both a mobility and a mental health issue. Policies to enable older adults to continue social engagement, decrease loneliness, and alleviate depression/anxiety are needed.

背景和目标:交通对于保持晚年的社会参与至关重要。缺乏交通工具与老年人的抑郁/焦虑症状显著相关。在本研究中,我们考察了孤独感在交通障碍和抑郁/焦虑症状之间的中介关系中的作用程度。研究设计和方法:使用2023年全国健康和老龄化趋势研究(N = 7547;年龄65岁以上),我们将交通障碍定义为阻碍老年人探亲访友、参加宗教仪式、参加俱乐部会议或外出享乐的交通问题。我们拟合了一个路径模型,并使用自举分析来检验中介效应,以获得间接效应及其95%置信区间(ci)的估计。结果:在研究人群中,有4.4%,即200万人报告了交通障碍。我们发现交通障碍对孤独和抑郁/焦虑症状的直接影响显著,孤独的间接影响显著(0.40,95% ci = [0.23, 0.57], z = 4.57, p)。交通应该被认为既是一个流动性问题,也是一个心理健康问题。需要制定政策,使老年人能够继续参与社会活动,减少孤独感,减轻抑郁/焦虑。
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Innovation in Aging
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