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Interaction between the impact of the Coronavirus disease 2019 pandemic and demographic characteristics on sexual/erectile dysfunction in Latin America: cross-sectional study 拉丁美洲2019冠状病毒病大流行与人口统计学特征对性/勃起功能障碍影响的相互作用:横断面研究
Constanza Alvear Pérez, Luciana de Barros Cavalcanti Michelutti, Maria Volpato Palharini, Luisa Pasqualotto Teixeira, V. Silva, L. Teixeira, Silvia L A Silva, S. Botelho
ABSTRACT Aim: Our objective was to investigate whether there is an interaction between the COVID-19 pandemic, demographic characteristics and erectile/sexual (E/S) function in individuals from Latin America. Materials and Methods: Cross-sectional study which included Latin American individuals over 18 years old, recruited through social media and interviewed between July and August 2020 by online surveys (Google Forms) in Portuguese and Spanish languages. The E/S function was evaluated through the following questionnaires: Simplified International Index of Erectile Function (IIEF-5) and Female Sexual Function Index (FSFI); while post-traumatic stress disorder (PTSD) triggered by the COVID-19 pandemic was assessed through the Impact of Event Scale Revised (IES-R). The data was analyzed by T Student, bivariate and multivariate logistic regression, with significance determined by the Wald test (p<0.05), using the R software v4.0. Results: Out of the 2016 individuals that responded to the survey, 1986 were included and 743 of them presented E/S dysfunction. PTSD occurrence was greater among people with E/S dysfunction when compared to those without E/S dysfunction, in the total score (males: IES-R=26.54[±19.17] and females: IES-R=35.92[±19.25]) and also in the three domains. It was found that those who do not live with a partner were 74% more likely to have E/S dysfunction, but living with a partner during the pandemic had a greater impact on E/S function. Conclusion: A negative interaction between the impact of the COVID-19 pandemic and erectile/sexual function of the Latin American population was observed, with greater implications among the individuals who live with their partners.
目的:我们的目的是调查COVID-19大流行、人口统计学特征和拉丁美洲个体勃起/性(E/S)功能之间是否存在相互作用。材料和方法:横断面研究包括18岁以上的拉丁美洲人,通过社交媒体招募,并在2020年7月至8月期间通过葡萄牙语和西班牙语的在线调查(谷歌表格)进行采访。E/S功能通过以下问卷进行评估:简化国际勃起功能指数(IIEF-5)和女性性功能指数(FSFI);通过事件影响量表修订(IES-R)评估新冠肺炎大流行引发的创伤后应激障碍(PTSD)。数据采用T - Student、双变量和多变量logistic回归分析,采用Wald检验(p<0.05),采用R软件v4.0进行显著性分析。结果:在回应调查的2016个人中,包括1986人,其中743人出现E/S功能障碍。PTSD在E/S功能障碍患者中的发生率高于无E/S功能障碍患者,在总得分(男性:IES-R=26.54[±19.17],女性:IES-R=35.92[±19.25])和三个领域中也高于无E/S功能障碍患者。研究发现,没有伴侣生活的人患E/S功能障碍的可能性要高74%,但在大流行期间与伴侣生活对E/S功能的影响更大。结论:COVID-19大流行的影响与拉丁美洲人群的勃起/性功能之间存在负相互作用,对与伴侣生活在一起的个体影响更大。
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引用次数: 2
Is biofeedback-assisted pelvic floor muscle training superior to pelvic floor muscle training alone in the treatment of dysfunctional voiding in women? A prospective randomized study 生物反馈辅助盆底肌训练在治疗女性排尿功能障碍方面是否优于单独盆底肌训练?一项前瞻性随机研究
E. Şam, A. Cinislioğlu, Fatih Kursat Yılmazel, S. O. Demirdogen, A. Yılmaz, I. Karabulut
ABSTRACT Purpose: To compare the effectiveness of biofeedback-assisted pelvic floor muscle training (PFMT) and PFMT alone on voiding parameters in women with dysfunctional voiding (DV). Materials and Methods: The patients in group 1 (34 patients) were treated with biofeedback-assisted PFMT, and the patients in group 2 (34 patients) were treated with PFMT alone for 12 weeks. The 24-hour frequency, average voided volume, maximum urine flow rate (Qmax), average urine flow rate (Qave), post-void residual urine volume (PVR), and the validated Turkish Urogenital Distress Inventory (UDI-6) symptom scores were recorded before and after 12 weeks of treatment. Results: At the end of treatment sessions, the Qmax and Qave values of the patients in group 1 were significantly higher than those in group 2, and the PVR in the patients in group 1 was significantly lower than those in group 2 (p=.026, .043, and .023, respectively). The average UDI-6 symptom scores of the patients in group 1 were significantly lower than those in group 2 (p=.034). Electromyography activity during voiding, in group 1 was significantly lower than in group 2 (41.2 vs. 64.7, respectively, p=.009). Conclusion: Biofeedback-assisted PFMT is more effective than PFMT alone in improving clinical symptoms, uroflowmetry parameters, and EMG activity during voiding.
目的:比较生物反馈辅助盆底肌训练(PFMT)和单独PFMT对排尿功能障碍(DV)女性排尿参数的影响。材料与方法:第1组(34例)采用生物反馈辅助PFMT治疗,第2组(34例)采用单纯PFMT治疗,疗程12周。记录治疗前后24小时尿频、平均排尿量、最大尿流率(Qmax)、平均尿流率(Qave)、排尿后残留尿量(PVR)及经验证的土耳其泌尿生殖窘迫量表(UDI-6)症状评分。结果:治疗结束时,组1患者Qmax、Qave值均显著高于组2,组1患者PVR显著低于组2 (p=。分别为0.026、0.043和0.023)。1组患者的平均UDI-6症状评分显著低于2组(p= 0.034)。排尿时,1组肌电活动明显低于2组(分别为41.2比64.7,p= 0.009)。结论:生物反馈辅助PFMT在改善临床症状、尿流指标和排尿时肌电活动方面比单纯PFMT更有效。
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引用次数: 2
Percutaneous and endoscopic combined treatment of bladder and renal lithiasis in mitrofanoff conduit 经皮内镜联合治疗米特凡诺夫导管内膀胱肾结石
R. Inzillo, Jean Emmanuel Kwe, Elisa Simonetti, Riccardo Milandri, M. Grande, D. Campobasso, S. Ferretti, B. Rocco, S. Micali, A. Frattini
ABSTRACT Introduction and Objectives: Treatment of bulky lithiasis in continent and non-continent urine storage reservoirs has been widely described and debated (1). Less is known about the optimal treatment in patients with a Mitrofanoff conduit. If voiding in these patients is incomplete, leading to recurrent symptomatic bacteriuria, formation of large lithiasis can be a common long-term complication (2, 3). Materials and Methods: This video describes a 19-year-old woman who underwent major open surgery at the age of six, with the configuration of a continent intestinal reservoir with a Mitrofanoff conduit. In 2020, she was referred to our center with a large stone in the reservoir and a minor stone in the inferior left renal calyx. We decided to proceed using a percutaneous approach with an “endovision technique” puncture for the bladder stone, combined with a retrograde intrarenal surgery for the renal stone. The MIP System “M size” was used to perform the percutaneous procedure, thus allowing a single-step dilation. The puncture and the dilation were followed endoscopically with a flexible ureterorenoscope avoiding the use of x-rays. The procedure was carried out as follows. The first step consisted in the insertion of a hydrophilic guidewire through the Mitrofanoff conduit. A flexible ureterorenoscope was then inserted coaxial to the guidewire. The percutaneous puncture, using an 80G needle, was followed endoscopically. Two guidewires were inserted, the first as a safety guidewire and the second for the tract dilation. The “single-step” dilation technique using the MIP system was performed and followed endoscopically. For the bladder lithotripsy, a dual-action lithotripter that combines ultrasonic and mechanical energy was used. Finally, a flexible ureterorenoscope and a basket for the retrieval of a single inferior caliceal stone were used. The procedure ended after positioning a single J stent in the left kidney and a nephrostomy tube in the reservoir. Results: The operative time was 80 minutes and the fluoroscopy time was 6 seconds. Hemoglobin and creatinine serum levels remained stable after the procedure and the patient was discharged on the third post-operative day, after removing both the single J and the nephrostomy tube. Follow-up lasted 12 months, with no bladder or renal stone recurrence, maintaining good continence of the Mitrofanoff conduit. Conclusion: In patients who have undergone several major surgeries a mini-invasive approach is advisable, not only for the morbidity of an open approach, but also for the increased risk of complications while handling an intestinal reservoir. Regarding a pure endoscopic approach, the passage of a nephroscope or a cystoscope through the Mitrofanoff conduit, combined with the continuous traction during the lithotripsy, could damage and compromise its continence. For this reason, the percutaneous approach is the most suitable method in these specific and rare cases.
摘要:导言和目的:在尿槽和非尿槽中治疗大块结石已经被广泛描述和争论(1)。对于米特罗法诺夫尿槽患者的最佳治疗方法知之甚少。如果这些患者排尿不完全,导致复发性症状性细菌尿,形成大结石可能是一个常见的长期并发症(2,3)。材料和方法:本视频描述了一名19岁的女性,她在6岁时接受了大的开放手术,配置了一个带有Mitrofanoff导管的大陆肠储液器。2020年,她因肾盂大结石和左下肾盂小结石转诊至我中心。我们决定继续采用经皮“内视技术”穿刺膀胱结石,并结合逆行肾内手术治疗肾结石。使用MIP系统“M尺寸”进行经皮手术,从而允许单步扩张。穿刺和扩张后,内镜下使用软性输尿管镜,避免使用x线。程序执行如下。第一步是通过Mitrofanoff导管插入亲水导丝。然后将柔性输尿管镜同轴插入导丝。经皮穿刺,使用80G针,内镜下进行。插入两根导丝,第一根作为安全导丝,第二根用于尿道扩张。使用MIP系统进行“单步”扩张技术,并在内窥镜下进行。膀胱碎石采用超声和机械能相结合的双作用碎石机。最后,使用软性输尿管镜和取石篮取出单个下盏结石。在左肾放置一个J型支架,在肾池放置肾造口管后,手术结束。结果:手术时间80分钟,透视时间6秒。术后血清血红蛋白和肌酐水平保持稳定,患者于术后第三天出院,同时取出单J管和肾造口管。随访12个月,无膀胱结石或肾结石复发,保持米特罗法诺夫输尿管良好的涵养。结论:在经历过多次大手术的患者中,微创入路是可取的,不仅考虑到开放入路的发病率,而且考虑到处理肠道储存库时并发症的风险增加。对于单纯的内镜入路,肾镜或膀胱镜通过Mitrofanoff导管,再加上在碎石过程中持续牵引,可能会破坏并损害其自控力。因此,经皮入路是这些特殊和罕见病例中最合适的方法。
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引用次数: 1
Corporoplasty: A simplified technique for clitoroplasty 阴蒂成形术:一种简化的阴蒂成形术
Ubirajara BARROSO JR, Eliakim Massuqueto, B. A. Venturini, T. Rosito, Marcelo Villalta, Leidy Paola Casas Grajales
ABSTRACT Introduction Clitoroplasty constitutes an important step in feminizing surgery for congenital adrenal hyperplasia (CAH) ( 1 ). In this video we present a technique that aims to preserve clitoral sensitivity and engorgement while minimizing the risk of neurovascular lesion. Materials and methods We present a video of a three-year-old girl with history of CAH classical form, PRADER-III, who underwent clitoroplasty. After an initial endoscopic evaluation of the urogenital sinus, the clitoris was degloved and a rectangular incision was made on the ventral corpora cavernosa 15mm above the corpora bifurcation and 0.5 mm below the coronal sulcus. The cavernous tissue was partially resected. The upper and lower borders of the rectangular gap were closed by a 5-0 PDS running suture similar to the Mikulicz technique. Next, the edge of the glans was deepithelialized to reduce its size. For improved clitoral positioning, the clitoris was sutured to the pubic fat. From that point onward the procedure followed that of a standard vaginoplasty using the en-bloc technique ( 2 - 4 ). Thus far we have performed this technique in 33 patients, with 31 of them being girls with CAH and 2 being women with clitoral hypertrophy. Conclusion Corporoplasty is a simplified technique for clitoroplasty, with the advantage being that is faster and safer than the technique that involves the dissection of the neurovascular bundle. In addition, corporoplasty has the possible benefit of preserving the cavernosal blood flow that permits the engorgement of the clitoris during sexual arousal.
阴蒂成形术是先天性肾上腺增生症(CAH)女性化手术的重要步骤(1)。在本视频中,我们介绍了一种旨在保持阴蒂敏感性和充盈的技术,同时将神经血管病变的风险降至最低。材料和方法我们提出了一个视频三岁女孩的历史CAH经典形式,PRADER-III,谁接受了阴蒂成形术。在对泌尿生殖窦进行初步内镜评估后,将阴蒂脱去手套,在下体分岔上方15mm、冠状沟下方0.5 mm的海绵体腹侧做一个矩形切口。部分切除海绵状组织。矩形间隙的上下边界用类似Mikulicz技术的5-0 PDS运行缝线闭合。接下来,对龟头边缘进行深度上皮化以减小其大小。为了改善阴蒂定位,将阴蒂与阴蒂脂肪缝合。从那时起,手术遵循使用整体技术的标准阴道成形术(2 - 4)。到目前为止,我们已经对33例患者进行了这项技术,其中31例是患有CAH的女孩,2例是患有阴蒂肥大的女性。结论体成形术是一种简便的阴蒂成形术,与神经血管束剥离术相比,具有快速、安全的优点。此外,阴茎成形术可能有保留海绵体血流量的好处,这使得阴蒂在性兴奋时能够膨胀。
{"title":"Corporoplasty: A simplified technique for clitoroplasty","authors":"Ubirajara BARROSO JR, Eliakim Massuqueto, B. A. Venturini, T. Rosito, Marcelo Villalta, Leidy Paola Casas Grajales","doi":"10.1590/S1677-5538.IBJU.2022.0018","DOIUrl":"https://doi.org/10.1590/S1677-5538.IBJU.2022.0018","url":null,"abstract":"ABSTRACT Introduction Clitoroplasty constitutes an important step in feminizing surgery for congenital adrenal hyperplasia (CAH) ( 1 ). In this video we present a technique that aims to preserve clitoral sensitivity and engorgement while minimizing the risk of neurovascular lesion. Materials and methods We present a video of a three-year-old girl with history of CAH classical form, PRADER-III, who underwent clitoroplasty. After an initial endoscopic evaluation of the urogenital sinus, the clitoris was degloved and a rectangular incision was made on the ventral corpora cavernosa 15mm above the corpora bifurcation and 0.5 mm below the coronal sulcus. The cavernous tissue was partially resected. The upper and lower borders of the rectangular gap were closed by a 5-0 PDS running suture similar to the Mikulicz technique. Next, the edge of the glans was deepithelialized to reduce its size. For improved clitoral positioning, the clitoris was sutured to the pubic fat. From that point onward the procedure followed that of a standard vaginoplasty using the en-bloc technique ( 2 - 4 ). Thus far we have performed this technique in 33 patients, with 31 of them being girls with CAH and 2 being women with clitoral hypertrophy. Conclusion Corporoplasty is a simplified technique for clitoroplasty, with the advantage being that is faster and safer than the technique that involves the dissection of the neurovascular bundle. In addition, corporoplasty has the possible benefit of preserving the cavernosal blood flow that permits the engorgement of the clitoris during sexual arousal.","PeriodicalId":13674,"journal":{"name":"International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology","volume":"13 1","pages":"726 - 727"},"PeriodicalIF":0.0,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74399669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recombinant gonadotropin therapy to improve spermatogenesis in nonobstructive azoospermic patients – A proof of concept study 重组促性腺激素治疗改善非阻塞性无精子症患者的精子发生-概念验证研究
R. Laursen, B. Alsbjerg, H. Elbaek, B. Povlsen, K. B. S. Jensen, Jette Lykkegaard, S. Esteves, P. Humaidan
ABSTRACT Purpose: Nonobstructive azoospermia (NOA) associated with primary spermatogenic failure is a common cause of male infertility usually considered untreatable; however, some reports have suggested that hormonal stimulation to boost the intra-testicular testosterone level and spermatogenesis might increase the chance of achieving pregnancy using homologous sperm. Materials and Methods: We report a series of eight NOA males who received long-term treatment with recombinant human chorionic gonadotropin twice a week for spermatogenesis stimulation. Six males received additional recombinant follicle-stimulating hormone (FSH) supplementation 150-225 IU twice weekly. Results: After recombinant gonadotropin therapy, viable spermatozoa were retrieved from the ejaculate in two patients and by testicular sperm aspiration (TESA) in another two subjects. Singleton spermatozoon retrieved from testes were frozen by vitrification on Cell-Sleeper devices. Two live births were obtained after intracytoplasmic sperm injection with ejaculated spermatozoa and one live birth and an ongoing pregnancy using thawed spermatozoa from TESA. Conclusion: Our proof-of-concept study indicates that hormonal therapy with recombinant gonadotropins could be considered in infertile men with NOA as an alternative to sperm donation. Large-scale studies are needed to substantiate hormone stimulation therapy with recombinant gonadotropins in routine clinical practice for this severe form of male infertility.
目的:非阻塞性无精子症(NOA)与原发性生精功能障碍相关,是男性不育症的常见原因,通常被认为是无法治疗的;然而,一些报告表明,通过激素刺激来提高睾丸内睾丸激素水平和精子发生可能会增加使用同源精子怀孕的机会。材料和方法:我们报道了一系列的8名NOA男性,他们接受了重组人绒毛膜促性腺激素的长期治疗,每周两次,以刺激精子发生。6名男性接受额外的重组卵泡刺激素(FSH)补充150-225 IU,每周两次。结果:2例患者经重组促性腺激素治疗后,通过睾丸精子抽吸(TESA)获得活精子。从睾丸中取出的单胎精子在Cell-Sleeper装置上通过玻璃化冷冻。用射精精子注射胞浆内精子后获得了2例活产,用TESA解冻的精子获得了1例活产和1例妊娠。结论:我们的概念验证研究表明,重组促性腺激素的激素治疗可以考虑作为精子捐献的替代方法。需要大规模的研究来证实在常规临床实践中使用重组促性腺激素进行激素刺激治疗这种严重形式的男性不育症。
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引用次数: 6
Step-by-step optimisation of robotic-assisted radical prostatectomy using augmented reality 利用增强现实逐步优化机器人辅助根治性前列腺切除术
J. Noël, M. Moschovas, E. Patel, T. Rogers, J. Marquinez, B. Rocco, A. Mottrie, V. Patel
ABSTRACT Introduction: Surgical training will be complemented by digitalisation, as the COVID 19 pandemic continues (1). Proximie is an augmented reality (AR) platform that can display up to 4 native camera views, with live or semi live telementoring. It can optimise ergonomics of the surgeon at the console (2), and robotic instrument orientation. We describe the utilisation of Proximie as a step-by-step guide in a robotic assisted radical prostatectomy (RARP). Surgical Technique: Author V. P. performed a transperitoneal multiport da Vinci Xi RARP with the Proximie platform: a laptop computer, multiple HD webcams, microphones and speakers. Using an HDMI cable to the Intuitive Surgical tower, output display from the console and an additional laparoscopic tower is shown. Each webcam was mounted to the side armrests of the console, directed at the surgeon's hands. An independent ‘drop in’ laparoscope via an additional 5mm left upper quadrant port was utilised. Observers can visualise the AR platform's recordings on a laptop and/or smartphone. A PTZ (pan-tilt-zoom) camera can capture the operating room, bedside assistant, ports and patient position. Our video demonstrates three of four camera views for posture, forearm, wrist, hand, and finger orientation, relative to the translated robotic steps. A pincer grasp of the endowrist manipulator during anastomosis allows optimal robotic wrist rotation. The second laparoscopic camera view demonstrated intracorporeal angles of robotic arm and bedside assistant's instrument position for critical steps such as nerve sparing and anastomosis (3). The console time was 100 minutes, no intraoperative complications, or delay in image transmission occurred with utilising the platform. Considerations: An AR platform can create deeper learning for RARP in real time or recorded sessions. Two-way verbal and visual communication with ability to annotate on screen, allows long distance mentoring. The platform's utility can be accessed in anywhere, to project surgeons beyond their immediate environment. This allows for democratisation of access to high volume institutions and their evolution of techniques (4), to assist patients globally. Potential developments are artificial intelligence (AI) networks analysing repository of such recorded data, to identify intraoperative hand motion and robotic instrument tracking. AR is a pertinent building block to enhance robotic training, skill dissemination, precision medicine (5) and surgery overall.
导语:随着COVID - 19大流行的持续,外科培训将辅以数字化(1)。Proximie是一个增强现实(AR)平台,可以显示多达4个本地摄像头视图,支持实时或半实时远程监控。它可以优化外科医生在控制台的人体工程学(2),以及机器人仪器的定位。我们描述了在机器人辅助根治性前列腺切除术(RARP)中使用Proximie作为一步一步的指南。使用HDMI电缆连接Intuitive Surgical塔,显示控制台的输出显示和额外的腹腔镜塔。每个网络摄像头都安装在控制台的侧扶手上,对准外科医生的手。通过左侧上象限额外5mm的端口使用独立的“插入”腹腔镜。观察者可以在笔记本电脑和/或智能手机上可视化AR平台的记录。PTZ (pan-tilt-zoom)摄像机可以捕捉手术室、床边助手、端口和病人的位置。我们的视频展示了相对于翻译机器人步骤的姿势、前臂、手腕、手和手指方向的四个摄像机视图中的三个。钳式腕内机械手在吻合过程中可以实现最佳的机械手腕旋转。第二次腹腔镜相机视图显示机器人手臂的体腔角度和床边助手的器械位置,用于神经保留和吻合等关键步骤(3)。控制台时间为100分钟,使用该平台未发生术中并发症或图像传输延迟。注意事项:AR平台可以在实时或录制会话中为RARP创建更深入的学习。双向口头和视觉交流,能够在屏幕上注释,允许远程指导。该平台的实用功能可以在任何地方访问,以预测外科医生的直接环境。这允许进入高容量机构的民主化及其技术的发展(4),以帮助全球患者。潜在的发展是人工智能(AI)网络分析这些记录数据的存储库,以识别术中手部运动和机器人仪器跟踪。增强现实是增强机器人训练、技能传播、精准医疗(5)和外科手术的相关组成部分。
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引用次数: 1
Mobile health may improve evaluation of lower urinary tract symptoms 移动医疗可改善对下尿路症状的评估
Pub Date : 2021-10-01 DOI: 10.1590/S1677-5538.IBJU.2021.0211.1
C. Gomes, J. Moromizato, Lucia S Ribeiro
The evaluation of patients with lower urinary tract symptoms (LUTS) is primarily based on clinical history and physical examination. Measuring the frequency and severity of LUTS adds important information for the characterization and management of lower urinary tract disorders (1, 2). Bladder diaries and uroflowmetry may be invaluable for symptom characterization. The recording of volume and time of each void by the patient is referred to as a frequency volume chart (FVC). Inclusion of information like fluid intake, use of pads, incontinence episodes or symptom severity is termed a bladder diary (1). The FVC provides data on total voided volume, day-time and night-time voiding frequency, nocturnal urinary volume and individual voided volumes. The maximum voided volume (MVV) is an important parameter of the voiding diary as it corresponds to the functional bladder capacity. It may be important to improve our understanding of bladder sensation, overactive bladder symptoms, polyuria and overflow incontinence (3). It may be used to clinically phenotype patients and help counseling regarding fluid intake and timed voiding (3). It may also assist in monitoring patient ́s response to treatment (2). The amount of information to be included and the duration of a bladder diary is variable, but typically should take from three to seven days (4). In this study, based on the perception that patients often have a greater MVV during office uroflowmetry than that seen in the bladder diary, the authors compared these two non-invasive methods by which MVV can be determined. They used a database of over seven hundred patients evaluated for LUTS who completed a 24-hour bladder diary independently using a smartphone application. They found that there is a difference between the two measurement tools, and that the maximum voided volume recorded in a bladder diary (BD-MVV) is usually greater than that obtained at the time of uroflow (Q-MVV). They suggested that for a more reliable assessment of MVV in men and women, both Q-MVV and BD-MVV should be assessed and that the larger of the two values is a more reliable assessment of MVV (5). It is important to highlight the use of a mobile app for the completion of the voiding diary in this study. Mobile health (mHealth) is an attractive and expanding tendency within LUTS care, both from the viewpoint of urologists and also by health systems and for research (6, 7). Typically, mHealth is based on a smartphone app that may help in the evaluation, monitoring and/or treatment of a health condition. mHealth has been used in urology for prostate cancer, urinary stones, LUTS, urinary incontinence and urinary tract infections and its use has gained importance with the COVID-19 pandemic (8). In the urinary stone field, apps may prevent forgetting a double-J catheter (9). For prostate cancer, apps may help physicians to stage patients and calculate disease risk and they EDITORIAL COMMENT Vol. 47 (6): 1195-1197, November December, 2021
下尿路症状(LUTS)患者的评估主要基于临床病史和体格检查。测量LUTS的频率和严重程度为下尿路疾病的表征和治疗提供了重要的信息(1,2)。膀胱日记和尿流测量对于症状表征可能是非常宝贵的。患者记录每个空洞的体积和时间称为频率体积图(FVC)。膀胱日记包括液体摄入量、尿垫使用情况、尿失禁发作或症状严重程度等信息(1)。膀胱日记提供总排尿量、白天和夜间排尿频率、夜间排尿量和个人排尿量等数据。最大排尿量(MVV)是排尿日记的一个重要参数,因为它对应于膀胱功能容量。提高我们对膀胱感觉、膀胱过度活跃症状、多尿和溢尿失禁的理解可能很重要(3)。它可以用于临床表型患者,并帮助咨询有关液体摄入和定时排尿(3)。它也可以帮助监测患者对治疗的反应(2)。要包括的信息量和膀胱日记的持续时间是可变的,但通常应该从3到7天(4)。在这项研究中,基于患者在办公室尿流测量中通常比膀胱日记中看到的MVV更大的认知,作者比较了这两种可以确定MVV的非侵入性方法。他们使用了一个数据库,该数据库包含了700多名LUTS患者,这些患者使用智能手机应用程序独立完成了24小时膀胱日记。他们发现两种测量工具之间存在差异,膀胱日记(BD-MVV)中记录的最大空气量通常大于尿流(Q-MVV)时获得的空气量。他们建议,为了更可靠地评估男性和女性的MVV,应该同时评估Q-MVV和BD-MVV,并且两个值中较大的值对MVV的评估更可靠(5)。在本研究中,重要的是要强调使用移动应用程序来完成排尿日记。从泌尿科医生、卫生系统和研究的角度来看,移动医疗(mHealth)是LUTS护理中一个有吸引力和不断扩大的趋势(6,7)。通常,移动医疗是基于智能手机应用程序,可以帮助评估、监测和/或治疗健康状况。移动健康已经在泌尿外科中用于前列腺癌、尿路结石、LUTS、尿失禁和尿路感染,随着COVID-19大流行,它的使用变得越来越重要(8)。在尿路结石领域,应用程序可以防止忘记双j导管(9)。对于前列腺癌,应用程序可以帮助医生对患者进行分期并计算疾病风险,他们EDITORIAL COMMENT Vol. 47 (6): 1195-1197, November December, 2021
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引用次数: 1
Treatment of complex urethral stenosis in public centers from developing countries in 21st century 21世纪发展中国家公共中心复杂性尿道狭窄的治疗
S. Tucci Jr., Henrique Florindo
Access to surgical treatment may be the only solution for preventing chronic disabilities and mortality (1) in cases of traumatic injuries and countless other situations that significantly affect quality of life such as iatrogenic, inflammatory or neoplastic injury. Notwithstanding successful prevention strategies, these conditions are responsible for a significant portion of disease burden in the population. In practice, speedy access to essential surgery is not always widely guaranteed (2), although it is part of the human right to health. In developing countries, where the most appropriate treatment for various diseases is not always readily available (2), there is a high incidence of complications from delays in diagnosis or access to specialized centers. In Brazil, this is the context in which complex urethral stenosis in public university institutions linked to the Unified Health System is approached. Male urethral stenosis has significant negative impact on patients’ quality of life. Its pathophysiology is better known and differences between developed and developing countries must be considered. The recent study by Astolfi et al, (3) evaluating 899 patients, shows that in Brazil iatrogenesis was the most frequent cause (43.2%), followed by idiopathic (21.7%) and traumatic (21.5%). Of the inflammatory causes (13.7%), the largest part was due to scleroatrophic lichen (66.7%), and 33.4% to infectious urethritis. Regarding the stenosis site, Palminteri et al. (4) showed that in developed countries, stenosis occurs mainly in the anterior urethra (92.2%), particularly in the bulbar segment (45.9%), with involvement of the posterior urethra in only 7.8% of cases (5). Most trauma-related stenosis occurred in urethral lesions associated with pelvic fractures (62.7%) and 62.7% were associated with perineal trauma. Of iatrogenic causes, 59% were secondary to urethral instrumentation (catheterization and other procedures), 24.8% due to procedures such as prostatectomy, radiotherapy and postectomy, and 16.2% following failure to correct hypospadias. Such demographic data are useful in guiding the development of preventive and therapeutic population strategies, as well as being important for educational guidance in relation to manipulation of the urethra (6), from vesicoureteral catheterization to instrumentation of the urethra in therapeutic procedures and, above all, to learn the different urethroplasty techniques. Strategies must be guided by the Unified Health System (SUS) as set forth in Article 5 of Law 8.080 of September 1990, and educational guidance is an obligation of medical schools and specific courses in Urology as a specialty. The SUS offers universal coverage and free access to all levels of health care for each person Treatment of complex urethral stenosis in public centers from developing countries in 21st century _______________________________________________
在创伤性损伤和无数其他严重影响生活质量的情况下,如医源性、炎症性或肿瘤性损伤,获得手术治疗可能是预防慢性残疾和死亡的唯一解决方案。尽管采取了成功的预防战略,但这些疾病造成了人口中很大一部分疾病负担。在实践中,迅速获得基本手术并不总是得到广泛保证(2),尽管这是健康权的一部分。在发展中国家,各种疾病的最适当治疗方法并不总是现成的(2),由于诊断延误或无法进入专门中心,并发症的发生率很高。在巴西,这是与统一卫生系统相关的公立大学机构复杂尿道狭窄的背景。男性尿道狭窄对患者生活质量有显著的负面影响。它的病理生理学更为人所知,必须考虑到发达国家和发展中国家之间的差异。Astolfi等人(3)最近对899例患者进行的研究显示,在巴西,医源性是最常见的原因(43.2%),其次是特发性(21.7%)和外伤性(21.5%)。在炎症原因中,以硬萎缩性地衣(66.7%)为主(13.7%),感染性尿道炎占33.4%。关于狭窄部位,Palminteri等(4)研究表明,在发达国家,狭窄主要发生在前尿道(92.2%),尤其是球段(45.9%),累及后尿道的病例仅占7.8%(5)。创伤性狭窄多发生在骨盆骨折相关的尿道病变中(62.7%),62.7%与会阴创伤相关。医源性原因中,59%继发于尿道内固定(置管和其他手术),24.8%继发于前列腺切除术、放疗和术后手术,16.2%继发于尿道下裂矫正失败。这样的人口统计数据对于指导预防和治疗人群策略的发展是有用的,同时对于尿道操作的教育指导也是重要的(6),从膀胱输尿管导尿到治疗过程中的尿道器械,最重要的是,学习不同的尿道成形术技术。战略必须以1990年9月第8.080号法律第5条规定的统一卫生系统(SUS)为指导,教育指导是医学院和泌尿外科专业特定课程的义务。统一卫生系统为每个人提供普遍覆盖和免费获得各级卫生保健的机会,在21世纪发展中国家的公共中心治疗复杂尿道狭窄_______________________________________________
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引用次数: 1
Impact of COVID-19 on education, health and lifestyle behaviour of Brazilian urology residents COVID-19对巴西泌尿外科住院医师教育、健康和生活方式行为的影响
J. Prezotti, J. Henriques, L. Favorito, A. F. Canalini, M. Machado, Thulio B. V. Brandão, Akemi M. V. Barbosa, J. Moromizato, Karin M. J. Anzolch, Roni de C. Fernandes, Fransber R. A. Rodrigues, C. H. Bellucci, C. Silva, A. Pompeo, J. de Bessa, C. Gomes
Objectives: To evaluate the impact of COVID-19 on clinical and surgical practice, educational activities, health and lifestyle behavior of Brazilian urology residents. Materials and Methods: A web-based survey was sent to 468 Brazilian urology residents from postgraduate years (PGY) 3 to 5 to collect data on clinical practice and training after 4 months of COVID-19. We also assessed health-related and behavior changes, rate of infection by SARS-CoV-2, deployment to the front line of COVID-19, residents concerns, and access to personal protective equipment (PPE). Results: Massive reductions in elective and emergency patient consultations, diagnostic procedures and surgeries were reported across the country, affecting PGY 3 to 5 alike. Most in-person educational activities were abolished. The median damage to the urological training expected for 2020 was 6.0 [3.4 -7.7], on a scale from 0 to 10, with senior residents estimating a greater damage (P< 0.001). Educational interventions developed included online case-based discussions, subspeciality conferences and lectures, and grand rounds. Most senior residents favored extending residency to compensate for training loss and most younger residents favored no additional training (p< 0.001). Modifications in health and lifestyle included weight gain (43.8%), reduced physical activity (68.6%), increased alcoholic intake (44.9%) and cigarette consumption (53.6%), worsening of sexual life (25.2%) and feelings of sadness or depression (48,2%). Almost half were summoned to work on the COVID-19 front-line and 24.4% had COVID-19. Most residents had inadequate training to deal with COVID-19 patients and most reported a shortage of PPE. Residents concerns included the risk of contaminating family members, being away from residency program, developing severe COVID-19 and overloading colleagues. Conclusions: COVID-19 had a massive impact in Brazilian urology residents training, health and lifestyle behavior, which may reflect what happened in other medical specialties. Studies should confirm these findings to help developing strategies to mitigate residents losses.
目的:评估2019冠状病毒病对巴西泌尿外科住院医师临床和手术实践、教育活动、健康和生活方式行为的影响。材料与方法:对468名巴西泌尿外科研究生3 - 5年级住院医师进行网络调查,收集新冠肺炎4个月后的临床实践和培训数据。我们还评估了健康相关和行为变化、SARS-CoV-2感染率、部署到COVID-19前线、居民关注的问题以及获得个人防护装备(PPE)的情况。结果:据报道,全国各地的选择性和紧急病人咨询、诊断程序和手术都大幅减少,影响了PGY 3至5。大多数面对面的教育活动被取消。预计2020年泌尿科培训的中位数损害为6.0[3.4 -7.7],在0到10的范围内,老年住院医师估计的损害更大(P< 0.001)。开发的教育干预措施包括基于案例的在线讨论、亚专业会议和讲座以及大型研讨会。大多数老年住院医师倾向于延长住院时间以弥补培训损失,而大多数年轻住院医师倾向于不进行额外培训(p< 0.001)。健康和生活方式的改变包括体重增加(43.8%)、体力活动减少(68.6%)、饮酒增加(44.9%)和吸烟增加(53.6%)、性生活恶化(25.2%)以及感到悲伤或抑郁(48.2%)。近一半的人被召唤到新冠肺炎一线工作,24.4%的人感染了新冠肺炎。大多数居民没有接受足够的培训来应对COVID-19患者,大多数人报告缺乏个人防护装备。居民们担心的问题包括感染家庭成员的风险、远离住院医师计划、患上严重的COVID-19以及同事超负荷工作。结论:2019冠状病毒病对巴西泌尿外科住院医师培训、健康和生活方式行为产生了巨大影响,这可能反映了其他医学专业的情况。研究应证实这些发现,以帮助制定减轻居民损失的策略。
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引用次数: 21
Luts-V: A new simplified score for assessing lower urinary tract symptoms in men Luts-V:一种评估男性下尿路症状的新的简化评分
C. Silva, Ueslei Menezes de Araujo, M. Alvaia, K. S. Freitas, T. Tiraboschi, C. Gomes, J. B. Bessa Júnior
OBJECTIVE: To validate a new simplified score for the assessment of men with LUTS (LUTS-V). METHODS: We made adjustments to the VPSS, resulting in a new simplified instrument (LUTS visual score - LUTS-V). In a pilot study, LUTS-V was administered to 50 men to identify interpretation issues. We used the International Prostate Symptom Score (IPSS) as the gold standard to validate the new tool in 306 men. The total IPSS and LUTS-V scores for each subject were evaluated and we used Bland-Altman analysis and Pearson's correlation plot to assess the agreement between the scores. A ROC curve was utilized to determine the diagnostic accuracy of LUTS-V and its diagnostic properties were described in terms of sensitivity, specificity, positive, and negative predictive values. RESULTS: Median age was 59 [52-67] years and, according to the IPSS, 26 (8.7%) patients had severe symptoms, while 99 (33%) had moderate symptoms, and 175 (58.3%) had mild symptoms. We found a positive correlation between the IPSS and LUTS-V (r = 0.72; p < 0.0001). The bland-Altman analysis showed good agreement between the two questionnaires. We found LUTS-V to have a diagnostic accuracy to detect more severe cases of 83% (95% CI: [78-87%]; p < 0.001), as estimated by the area under the ROC curve. The cut-off value of [≥] 4 points was the best threshold, with a sensitivity of 74% and a specificity of 78%, which resulted in a negative predictive value of 81% and a positive predictive value of 71% in this scenario. Median completion time was 0.51 [0.41-1.07] min for LUTS-V and 2.5 [2.2-3.4] min for the IPSS (p < 0.0001). Also, 91.5% of patients completed the questionnaires with no help, while the other 8.5% were interviewed. CONCLUSION: LUTS-V is a simple, self-administered tool with a significant discriminating power to identify patients with moderate to severe symptoms.
目的:验证一种新的简化LUTS男性评估评分(LUTS- v)。方法:我们对VPSS进行调整,形成一种新的简化仪器(LUTS视觉评分- LUTS- v)。在一项初步研究中,LUTS-V被用于50名男性,以确定解释问题。我们使用国际前列腺症状评分(IPSS)作为金标准来验证306名男性的新工具。评估每个受试者的IPSS和LUTS-V总分,并使用Bland-Altman分析和Pearson相关图来评估得分之间的一致性。采用ROC曲线确定LUTS-V的诊断准确性,并从敏感性、特异性、阳性预测值和阴性预测值等方面描述其诊断特性。结果:中位年龄为59岁[52-67]岁,根据IPSS,重度症状26例(8.7%),中度症状99例(33%),轻度症状175例(58.3%)。我们发现IPSS与LUTS-V呈正相关(r = 0.72;P < 0.0001)。bland-Altman分析显示两份问卷吻合良好。我们发现LUTS-V检测更严重病例的诊断准确率为83% (95% CI: [78-87%];p < 0.001),由ROC曲线下的面积估计。截断值[≥]4分为最佳阈值,敏感性为74%,特异性为78%,阴性预测值为81%,阳性预测值为71%。LUTS-V的中位完成时间为0.51 [0.41-1.07]min, IPSS的中位完成时间为2.5 [2.2-3.4]min (p < 0.0001)。91.5%的患者在没有帮助的情况下完成了问卷,而其他8.5%的患者接受了访谈。结论:LUTS-V是一种简单、自我给药的工具,具有显著的鉴别能力,可识别中重度症状患者。
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引用次数: 3
期刊
International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology
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