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Effects of workday characteristics and job demands on recovery from work among Finnish home care nurses: a multi-source cross-sectional study. 工作日特征和工作需求对芬兰家庭护理护士工作恢复的影响:一项多来源横断面研究。
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-01 Epub Date: 2023-11-30 DOI: 10.1007/s00420-023-02026-y
Visa Väisänen, Salla Ruotsalainen, Pihla Säynäjäkangas, Satu Mänttäri, Jaana Laitinen, Timo Sinervo

Objective: Ageing populations and poor care workforce availability are causing increasing job demands for home care nurses across Europe. While recovery from work helps sustain work ability and wellbeing, past research has relied mainly on self-reported measures of health, stressors, and recovery. This study aims to examine how objective and subjective job demands are associated with measured day-time recovery among home care nurses.

Methods: Heart rate variability recording was conducted for 95 Finnish home care nurses. The study participants documented their work tasks throughout the workday and filled a wellbeing questionnaire. The amount of care time, breaktime, number of different weekly clients, and their care needs were obtained from the survey. The associations between job demands and measured day-time recovery were analysed using multivariate linear regression.

Results: The amount of day-time recovery was on average 75 min. The number of different clients during the workday (e.g., care continuity) and higher care needs of the clients were associated with lower day-time recovery. Additionally, something slightly disrupting the course of the workday was associated with increased recovery.

Conclusions: Our findings indicate that reducing especially the objective job demands (workday characteristics) can contribute to better day-time recovery among home care nurses. To help sustain work ability and improve wellbeing, day-time recovery can be promoted with better work scheduling that supports care continuity and ensures sufficient care resources and support for nurses with many clients or clients with high care needs.

目的:人口老龄化和护理人力资源不足导致整个欧洲对家庭护理护士的工作需求不断增加。虽然从工作中恢复有助于维持工作能力和幸福感,但过去的研究主要依赖于自我报告的健康、压力源和恢复情况。本研究旨在探讨客观和主观工作需求与家庭护理护士日间恢复的关系。方法:对95名芬兰家庭护理护士进行心率变异性记录。研究参与者记录了他们整个工作日的工作任务,并填写了一份健康问卷。通过问卷调查获得护理时间、休息时间、每周不同客户的数量以及他们的护理需求。使用多元线性回归分析工作需求与测量白天恢复之间的关系。结果:日间恢复时间平均为75分钟。工作日内不同客户的数量(如护理连续性)和客户较高的护理需求与较低的日间恢复时间相关。此外,稍微扰乱工作日进程的事情与恢复速度加快有关。结论:我们的研究结果表明,降低客观工作需求(工作日特征)有助于家庭护理护士更好的日间恢复。为了帮助维持工作能力和改善健康,可以通过更好的工作安排来促进日间康复,以支持护理的连续性,并确保有足够的护理资源,并为有许多客户或有高护理需求的客户的护士提供支持。
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引用次数: 0
Cross-sectional associations of weekly time, social context, and motivation of exercise with mental health among workers. 工作人员每周时间、社会环境和锻炼动机与心理健康的横断面关联。
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-01 Epub Date: 2023-11-10 DOI: 10.1007/s00420-023-02021-3
Kazuhiro Harada, Shuhei Izawa, Nanako Nakamura-Taira, Toru Yoshikawa, Rie Akamatsu, Hiroki Ikeda, Tomohide Kubo

Purpose: Exercise is considered a strategy to promote mental health among workers. However, the optimal exercise conditions that promote mental health benefits for workers are still unclear. This study examined the cross-sectional associations of weekly exercise time duration, social context of exercise, and exercise motivation levels with the mental health among Japanese workers.

Methods: A web-based cross-sectional questionnaire survey was conducted among 18,902 workers, aged 20-59 years. The mental health variables (psychological distress, psychological stress reaction, physical stress reaction, job satisfaction, and work engagement), exercise participation (non-exercisers, exercisers), and demographic factors of all responders were measured. Weekly exercise time, social context of exercise (alone only, with others only, both alone and with others), and exercise motivation (non-regulation, external/introjected regulation, identified regulation, integrated regulation, and internal regulation) were also measured amongst exercisers. After adjusting for demographic factors, multiple regression analyses were conducted.

Results: Exercisers had significantly lower psychological distress, lower psychological and physical stress reactions, higher job satisfaction, and higher work engagement than non-exercisers. Among exercisers, while weekly exercise time duration and social context of exercise were not clearly and robustly associated with mental health variables, respondents with intrinsic regulation had significantly lower psychological distress, lower psychological and physical stress reaction, higher job satisfaction, and higher work engagement than those with lower self-determined motivations.

Conclusions: This study found that more self-determined exercise motivation is closely associated with advantageous mental health variables, than the duration or the social context of exercise among Japanese workers.

目的:锻炼被认为是促进员工心理健康的一种策略。然而,促进工人心理健康的最佳锻炼条件仍不清楚。本研究调查了日本工人每周锻炼时间、锻炼的社会背景和锻炼动机水平与心理健康的横断面关联。方法:对18902名年龄在20-59岁之间的工人进行网络横断面问卷调查。测量了所有应答者的心理健康变量(心理困扰、心理压力反应、身体压力反应、工作满意度和工作投入)、锻炼参与度(非锻炼者、锻炼者)和人口统计学因素。还测量了锻炼者的每周锻炼时间、锻炼的社会背景(仅限单独锻炼、仅与他人锻炼、单独锻炼和与他人锻炼)和锻炼动机(非调节、外部/内向调节、确定调节、综合调节和内部调节)。在对人口统计学因素进行调整后,进行了多元回归分析。结果:与不锻炼者相比,锻炼者的心理困扰显著降低,心理和身体压力反应显著降低,工作满意度显著提高,工作投入度显著提高。在锻炼者中,虽然每周锻炼时间和锻炼的社会背景与心理健康变量没有明确而有力的关联,但与那些自我决定动机较低的人相比,具有内在调节的受访者的心理困扰显著较低,心理和身体压力反应较低,工作满意度较高,工作参与度较高。结论:本研究发现,在日本工人中,与运动的持续时间或社会背景相比,更自主的运动动机与有利的心理健康变量密切相关。
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引用次数: 0
Association between diurnal temperature range and outpatient visits for urticaria disease in Lanzhou, China: a distributed lag nonlinear analysis. 中国兰州地区荨麻疹患者日间气温变化与门诊就诊的关系:一种分布滞后非线性分析。
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-01 Epub Date: 2023-11-11 DOI: 10.1007/s00420-023-02019-x
Yi Wu, Jing Zhang, Guodong Luo, Jianhong Zhang, Xiangdong Zhang, Bei Liao, Chunrui Shi

Background: A growing number of epidemiological studies have shown that daily temperatures are associated with urticaria. However, the relationship between daily changes in temperature and urticaria is unclear.

Objectives: To assess the diurnal temperature difference (DTR) effects on urticaria outpatient visits in Lanzhou, China.

Methods: Urticaria outpatient visits data during 2011-2019 were collected from three major tertiary hospitals in Lanzhou. Daily temperature data from the official website of China Meteorological Administration. Assessment of the relationship between urticaria outpatient volume and DTR in Lanzhou City using a distributed lag nonlinear model.

Results: A total of 83,022 urticaria visits were enrolled. There was a nonlinear relationship between DTR and urticaria outpatient visits and a lagged effect of DTR impact. The effects of high DTR on urticaria visits were not seen in all populations but in the male population and in the 15-59 age group. High DTR (P95: 18.2 °C) was associated with a 27% (95% CI: 0.01, 60.53%) and 31% (95% CI: 1.60, 68.99%) increase in the number of urticaria visits in the 21-day lag effect for the male cohort and the 15-59 year old cohort, respectively, compared with 11.5 °C, respectively.

Conclusions: Our study suggests that DTR is a potential risk factor for urticaria. The results of this study may provide a scientific basis for local governments to improve preventive measures in the health care system.

背景:越来越多的流行病学研究表明,日常温度与荨麻疹有关。然而,每日温度变化与荨麻疹之间的关系尚不清楚。目的:评估昼夜温差(DTR)对中国兰州荨麻疹门诊就诊的影响。方法:收集兰州市3家三级医院2011-2019年荨麻疹门诊就诊数据。每日气温资料来自中国气象局官方网站。用分布滞后非线性模型评价兰州市荨麻疹门诊人数与DTR的关系结果:共有83022例荨麻疹患者被纳入研究。DTR与荨麻疹门诊次数之间存在非线性关系,DTR影响存在滞后效应。高DTR对荨麻疹就诊的影响并非在所有人群中都可见,但在男性人群和15-59岁年龄组中可见。与11.5°C相比,高DTR (P95: 18.2°C)与21天滞后效应中男性队列和15-59岁队列的荨麻疹就诊数量分别增加27% (95% CI: 0.01, 60.53%)和31% (95% CI: 1.60, 68.99%)相关。结论:本研究提示DTR是荨麻疹的潜在危险因素。本研究结果可为地方政府改善卫生保健系统的预防措施提供科学依据。
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引用次数: 0
Overtime work is related to nonrestorative sleep independently of short sleep time among a Japanese occupational population. 在日本职业人群中,加班与非恢复性睡眠有关,与睡眠时间短无关。
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-01 Epub Date: 2023-12-04 DOI: 10.1007/s00420-023-02027-x
Hiromitsu Sekizuka, Hitoshi Miyake

Objective: The symptoms of insomnia are defined as difficulty falling asleep, difficulty staying asleep, and early awakening. Although also a symptom of insomnia, nonrestorative sleep (NRS) is clearly more associated with objective indices than other insomnia symptoms. However, the link between NRS and overtime work duration is poorly understood.

Methods: The results of a single year's medical examinations were investigated for 26,144 Japanese office workers who were 30 to 59 years old. NRS status and lifestyle were collected through a computer-assisted medical interview. The subjects were asked about the presence or absence of NRS and their lifestyles in the most recent two to three months. The subjects were asked about their sleep times and average overtime durations per month (< 20 h/month, ≥ 20 but < 40 h/month, ≥ 40 but < 60 h/month, and ≥ 60 h/month). The relationships between NRS and overtime work duration adjusted for sleep time were also analyzed.

Results: The proportion of subjects with NRS showed a stepwise increase as overtime work hours increased. A logistic regression analysis was performed using NRS as an objective variable. The multivariate analysis demonstrated that overtime work duration (OR, 1.13; 95% CI 1.10-1.17; P < 0.001; per one-category increase) was an independent determinant of NRS.

Conclusion: For office workers, long hours of overtime work increased the NRS prevalence at any sleep duration.

目的:将失眠的症状定义为入睡困难、保持睡眠困难和早醒。非恢复性睡眠(NRS)虽然也是失眠的一种症状,但与其他失眠症状相比,它与客观指标的关联明显更大。然而,NRS和加班时间之间的联系却鲜为人知。方法:对26144名30 ~ 59岁的日本上班族进行了一年的体检。通过计算机辅助医疗访谈收集NRS状态和生活方式。研究对象被问及是否存在NRS以及他们最近两到三个月的生活方式。研究对象被问及他们每月的睡眠时间和平均加班时间(结果:随着加班时间的增加,NRS受试者的比例呈逐步增加的趋势。以NRS为客观变量进行logistic回归分析。多变量分析表明,加班时间(OR, 1.13;95% ci 1.10-1.17;结论:对于上班族来说,长时间的加班工作增加了任何睡眠时间的NRS患病率。
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引用次数: 0
Effects of heat and personal protective equipment on thermal strain in healthcare workers: part B-application of wearable sensors to observe heat strain among healthcare workers under controlled conditions. 热和个人防护设备对医护人员热应变的影响:B部分可穿戴传感器在受控条件下观察医护人员热应力的应用。
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-01 Epub Date: 2023-11-10 DOI: 10.1007/s00420-023-02022-2
Razan Wibowo, Viet Do, Caroline Quartucci, Daniela Koller, Hein A M Daanen, Dennis Nowak, Stephan Bose-O'Reilly, Stefan Rakete

Purpose: As climate change accelerates, healthcare workers (HCW) are expected to be more frequently exposed to heat at work. Heat stress can be exacerbated by physical activity and unfavorable working requirements, such as wearing personal protective equipment (PPE). Thus, understanding its potential negative effects on HCW´s health and working performance is becoming crucial. Using wearable sensors, this study investigated the physiological effects of heat stress due to HCW-related activities.

Methods: Eighteen participants performed four experimental sessions in a controlled climatic environment following a standardized protocol. The conditions were (a) 22 °C, (b) 22 °C and PPE, (c) 27 °C and (d) 27 °C and PPE. An ear sensor (body temperature, heart rate) and a skin sensor (skin temperature) were used to record the participants´ physiological parameters.

Results: Heat and PPE had a significant effect on the measured physiological parameters. When wearing PPE, the median participants' body temperature was 0.1 °C higher compared to not wearing PPE. At 27 °C, the median body temperature was 0.5 °C higher than at 22 °C. For median skin temperature, wearing PPE resulted in a 0.4 °C increase and higher temperatures in a 1.0 °C increase. An increase in median heart rate was also observed for PPE (+ 2/min) and heat (+ 3/min).

Conclusion: Long-term health and productivity risks can be further aggravated by the predicted temperature rise due to climate change. Further physiological studies with a well-designed intervention are needed to strengthen the evidence for developing comprehensive policies to protect workers in the healthcare sector.

目的:随着气候变化的加速,医护人员在工作中预计会更频繁地暴露在高温下。身体活动和不利的工作要求(如穿戴个人防护装备)会加剧热应激。因此,了解其对HCW健康和工作表现的潜在负面影响变得至关重要。本研究使用可穿戴传感器,研究了HCW相关活动引起的热应激的生理影响。方法:18名参与者按照标准化方案,在受控的气候环境中进行了四次实验。条件为(a)22°C,(b)22°C.和PPE,(C)27°C.和(d)27°C和PPE。耳朵传感器(体温、心率)和皮肤传感器(皮肤温度)用于记录参与者的生理参数。结果:高温和个人防护用品对测量的生理参数有显著影响。在穿戴个人防护装备时,参与者的平均体温比不穿戴个人防护用品时高0.1°C。在27°C时,中位体温比22°C时高0.5°C。对于中值皮肤温度,穿戴个人防护装备会导致0.4°C的温度升高,而更高的温度会导致1.0°C的升高。PPE的中位心率也有所增加(+ 2/分钟)和加热(+ 3/min)。结论:由于气候变化,预测的气温上升可能会进一步加剧长期健康和生产力风险。需要通过精心设计的干预措施进行进一步的生理学研究,以加强制定全面政策保护医疗保健部门工作人员的证据。
{"title":"Effects of heat and personal protective equipment on thermal strain in healthcare workers: part B-application of wearable sensors to observe heat strain among healthcare workers under controlled conditions.","authors":"Razan Wibowo, Viet Do, Caroline Quartucci, Daniela Koller, Hein A M Daanen, Dennis Nowak, Stephan Bose-O'Reilly, Stefan Rakete","doi":"10.1007/s00420-023-02022-2","DOIUrl":"10.1007/s00420-023-02022-2","url":null,"abstract":"<p><strong>Purpose: </strong>As climate change accelerates, healthcare workers (HCW) are expected to be more frequently exposed to heat at work. Heat stress can be exacerbated by physical activity and unfavorable working requirements, such as wearing personal protective equipment (PPE). Thus, understanding its potential negative effects on HCW´s health and working performance is becoming crucial. Using wearable sensors, this study investigated the physiological effects of heat stress due to HCW-related activities.</p><p><strong>Methods: </strong>Eighteen participants performed four experimental sessions in a controlled climatic environment following a standardized protocol. The conditions were (a) 22 °C, (b) 22 °C and PPE, (c) 27 °C and (d) 27 °C and PPE. An ear sensor (body temperature, heart rate) and a skin sensor (skin temperature) were used to record the participants´ physiological parameters.</p><p><strong>Results: </strong>Heat and PPE had a significant effect on the measured physiological parameters. When wearing PPE, the median participants' body temperature was 0.1 °C higher compared to not wearing PPE. At 27 °C, the median body temperature was 0.5 °C higher than at 22 °C. For median skin temperature, wearing PPE resulted in a 0.4 °C increase and higher temperatures in a 1.0 °C increase. An increase in median heart rate was also observed for PPE (+ 2/min) and heat (+ 3/min).</p><p><strong>Conclusion: </strong>Long-term health and productivity risks can be further aggravated by the predicted temperature rise due to climate change. Further physiological studies with a well-designed intervention are needed to strengthen the evidence for developing comprehensive policies to protect workers in the healthcare sector.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"35-43"},"PeriodicalIF":3.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10791845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72014207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What it takes to reduce sitting at work: a pilot study on the effectiveness and correlates of a multicomponent intervention. 减少久坐工作需要什么:一项关于多成分干预的有效性和相关性的试点研究。
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-01 Epub Date: 2023-11-10 DOI: 10.1007/s00420-023-02020-4
Jannik Porath, Laura I Schmidt, Juliane Möckel, Chiara Dold, Lisa Hennerkes, Alexander Haussmann

Objective: This study aimed to assess the feasibility and effects of a simple-to-implement multicomponent intervention to reduce sedentary time of office workers.

Methods: Six groups of eight to ten office workers took part in the two-week Leicht Bewegt intervention. Participants completed questionnaires at baseline (T0, n = 52), after 2 weeks (T1, n = 46), and after 5 weeks (T2, n = 38), including subjective sedentary measures and social-cognitive variables based on the health action process approach (HAPA). Objective sedentary measures were obtained using activPAL trackers.

Results: The intention to reduce sedentary behavior during work increased significantly from T0 to T1. Participants' objective and subjective sitting time decreased significantly from T0 to T1, corresponding to an average decrease per 8-h-workday of 55 min (d = - .66) or 74 min (d = - 1.14), respectively. This reduction persisted (for subjective sitting time) at T2 (d = - 1.08). Participants indicated a high satisfaction with the intervention.

Conclusions: The Leicht Bewegt intervention offers a feasible and effective opportunity to reduce sedentary behavior at work. Randomized controlled trials including longer follow-up time periods are needed to validate its benefits in different workplaces.

目的:本研究旨在评估一种简单易行的多组分干预措施的可行性和效果,以减少上班族的久坐时间。方法:六组八至十名上班族参加为期两周的Leicht-Bewegt干预。参与者在基线(T0,n = 52),2周后(T1,n = 46),并且在5周后(T2,n = 38),包括基于健康行动过程方法(HAPA)的主观久坐测量和社会认知变量。使用activPAL跟踪器获得了客观的久坐测量。结果:从T0到T1,减少工作中久坐行为的意愿显著增加。参与者的客观和主观坐着时间从T0到T1显著减少,对应于每8小时工作日平均减少55分钟(d = -.66)或74分钟(d = -1.14)。这种减少在T2(d)持续存在(对于主观坐着时间) = -1.08)。参与者对干预表示高度满意。结论:Leicht-Bewegt干预为减少工作中的久坐行为提供了一个可行而有效的机会。需要进行随机对照试验,包括更长的随访时间,以验证其在不同工作场所的益处。
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引用次数: 0
The combined effect of air pollution and non-optimal temperature on mortality in Shandong Province, China: establishment of air health index 中国山东省空气污染和非最佳气温对死亡率的综合影响:建立空气健康指数
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1007/s00420-023-02036-w
Shuyue Niu, Junli Tang, Kejia Hu, Xiaohui Xu, Jing Dong, Jie Chu, Xiaolei Guo, Haitao Wang, Yanwen Cao, Qi Zhao, Lovel Fornah, Zilong Lu, Wei Ma

Purpose

The air health index (AHI) captures the combined effects of air pollution and non-optimal temperatures and helps assess the atmospheric environment’s overall health risk. Shandong Province is a crucial industrial base in China, and the health effects of air pollution and non-optimal temperature cannot be ignored. To construct an AHI for Shandong Province and assess the district-level mortality burden due to AHI in the study area.

Methods

Daily district-specific mortality, meteorological, and air pollution data over 2013–2018 were collected in Shandong Province, China. The AHI construction eventually incorporated PM2.5 and NO2, O3, and non-optimal temperatures. Attributable fraction (AF) and attributable number (AN) were used to estimate the district-specific mortality burden attributable to AHI.

Results

The average AHI value observed in Shandong Province was 6. Our research revealed a positive association between the total AHI and total mortality, with an overall trend of a slow increase followed by a rapid increase. The exposure–response curves, when stratified by gender, age, and cause of death, were approximately consistent with the overall trend. The provincial attributable fraction (AF) was 5.31% (95% CI 4.58%, 5.91%), and the attributable number (AN) was 188,246 (95% CI 162,396, 209,533). Overall, higher ANs mainly appeared in the southwestern area, while higher values of AF were observed in the central-eastern and central-northern areas.

Conclusions

The air health index performs well in predicting death burden and can convey health risks related to exposure to the ambient environment to the public.

目的 空气健康指数(AHI)反映了空气污染和非最佳温度的综合影响,有助于评估大气环境的整体健康风险。山东省是中国重要的工业基地,空气污染和非最佳温度对健康的影响不容忽视。方法在中国山东省收集了 2013-2018 年期间各地区的死亡率、气象和空气污染数据。AHI 的构建最终纳入了 PM2.5、二氧化氮(NO2)、臭氧(O3)和非最佳温度。我们的研究发现,总 AHI 与总死亡率之间存在正相关,总体趋势是先缓慢上升后快速上升。按性别、年龄和死因分层后,暴露-反应曲线与总体趋势基本一致。该省的可归因比例(AF)为 5.31%(95% CI 4.58%,5.91%),可归因人数(AN)为 188,246 人(95% CI 162,396 人,209,533 人)。总体而言,较高的AN值主要出现在西南地区,而较高的AF值则出现在中东部和中北部地区。
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引用次数: 0
Occupational-related exposure to diesel exhaust and risk of leukemia: systematic review and meta-analysis of cohort studies 与职业相关的柴油废气暴露和白血病风险:队列研究的系统回顾和荟萃分析
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-24 DOI: 10.1007/s00420-023-02034-y
Darshi Shah, Vincent DeStefano, Giulia Collatuzzo, Federica Teglia, Paolo Boffetta

Purpose

Diesel exhaust (DE) is an established lung carcinogen. The association with leukemia is not well established. We conducted a systematic review and meta-analysis of cohort studies to determine the association between occupational DE exposure and risk of leukemia.

Methods

A systematic literature review was performed to identify all cohort studies on occupational exposure to DE and associated risk of leukemia. STROBE guidelines and PECOS criteria were followed. Meta-analyses with fixed effects (and random-effects model in cases of high heterogeneity) were performed to calculate summary relative risks (RR) and 95% confidence intervals (CI), including subgroup analyses by outcome (mortality or incidence), sex, geographic region, industry type, and study quality. Study quality was assessed using the the Joanna Briggs Institute (JBI) critical appraisal checklist for cohort studies.

Results

Of the 30 studies retained, 20 (8 from North America, 12 from Europe) reported a total of 33 estimates of the risk of leukemia. Overall, the relative risk (RR) of leukemia was 1.01 (95% CI = 0.97–1.05, I2 = 21.2%, n = 33); corresponding results for leukemia incidence and mortality were RR = 1.02 (95% CI = 0.98–1.06, I2 = 27.9%, n = 19) and RR = 0.91 (95% CI = 0.81–1.02, I2 = 0.0%, n = 15), respectively. The main results were confirmed in analyses by sex and geographic area. A statistically significant association was detected for miners (RR = 1.58, 95% CI = 1.15–2.15, I2 = 77.0%, n = 2) but not for other occupational groups. Publication bias was not detected (p = 0.7).

Conclusion

Our results did not indicate an association between occupational DE exposure and leukemia, with the possible exception of miners. Residual confounding cannot be excluded.

目的柴油废气(DE)是一种公认的肺致癌物。但其与白血病的关系尚未得到充分证实。我们对队列研究进行了系统性回顾和荟萃分析,以确定职业性柴油废气暴露与白血病风险之间的关联。方法我们进行了系统性文献回顾,以确定所有有关职业性柴油废气暴露和相关白血病风险的队列研究。研究遵循了 STROBE 指南和 PECOS 标准。采用固定效应进行 Meta 分析(异质性较高时采用随机效应模型),以计算汇总相对风险 (RR) 和 95% 置信区间 (CI),包括按结果(死亡率或发病率)、性别、地理区域、行业类型和研究质量进行亚组分析。研究质量采用乔安娜-布里格斯研究所 (Joanna Briggs Institute, JBI) 的队列研究关键评估清单进行评估。总体而言,白血病的相对风险 (RR) 为 1.01 (95% CI = 0.97-1.05, I2 = 21.2%, n = 33);白血病发病率和死亡率的相应结果分别为 RR = 1.02 (95% CI = 0.98-1.06, I2 = 27.9%, n = 19) 和 RR = 0.91 (95% CI = 0.81-1.02, I2 = 0.0%, n = 15)。按性别和地理区域进行的分析证实了主要结果。矿工(RR = 1.58,95% CI = 1.15-2.15,I2 = 77.0%,n = 2)与此有统计学意义,而其他职业群体则没有。结论我们的研究结果并未表明职业性 DE 暴露与白血病之间存在关联,但矿工可能是个例外。不能排除残余混杂因素。
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引用次数: 0
Occupational exposure to vapors, gasses, dusts, and fumes in relation to causes of death during 24 years in Helsinki, Finland 芬兰赫尔辛基 24 年间与蒸汽、气体、粉尘和烟雾的职业接触与死亡原因的关系
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-19 DOI: 10.1007/s00420-023-02031-1
Juuso Jalasto, Ritva Luukkonen, Ari Lindqvist, Arnulf Langhammer, Hannu Kankaanranta, Helena Backman, Eva Rönmark, Anssi Sovijärvi, Päivi Piirilä, Paula Kauppi

Purpose

Environmental particulate matter (PM) exposure has been shown to cause excess all-cause and disease-specific mortality. Our aim was to compare disease-specific mortality by estimated occupational exposure to vapors, gasses, dusts, and fumes (VGDF).

Methods

The data source is the Helsinki part of the population-based FinEsS study on chronic obstructive pulmonary diseases including information on age, education level, main occupation, sex, and tobacco smoking combined with death registry information. We compared estimated VGDF exposure to mortality using adjusted competing-risks regression for disease-specific survival analysis for a 24-year follow-up.

Results

Compared to the no-exposure group, the high occupational VGDF exposure group had sub-hazard ratios (sHR) of 1.7 (95% CI 1.3–2.2) for all cardiovascular-related and sHR 2.1 (1.5–3.9) for just coronary artery-related mortality. It also had sHR 1.7 (1.0–2.8) for Alzheimer’s or vascular dementia-related mortality and sHR 1.7(1.2–2.4) for all respiratory disease-related mortality.

Conclusion

Long-term occupational exposure to VGDF increased the hazard of mortality- to cardiovascular-, respiratory-, and dementia-related causes. This emphasizes the need for minimizing occupational long-term respiratory exposure to dust, gasses, and fumes.

目的环境颗粒物(PM)暴露已被证明会导致超常的全因死亡率和特定疾病死亡率。我们的目的是根据蒸汽、气体、粉尘和烟雾(VGDF)的估计职业暴露量来比较疾病特异性死亡率。方法数据来源于基于人群的慢性阻塞性肺病 FinEsS 研究的赫尔辛基部分,包括年龄、教育水平、主要职业、性别和吸烟等信息以及死亡登记信息。结果与未暴露组相比,高职业 VGDF 暴露组所有心血管相关死亡率的次危险比 (sHR) 为 1.7 (95% CI 1.3-2.2),仅冠状动脉相关死亡率的次危险比 (sHR) 为 2.1 (1.5-3.9)。结论 长期职业暴露于 VGDF 会增加心血管、呼吸系统和痴呆相关原因的死亡率。这强调了尽量减少职业性长期呼吸接触粉尘、气体和烟雾的必要性。
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引用次数: 0
Club cell protein (CC16) in serum as an effect marker for small airway epithelial damage caused by diesel exhaust and blasting fumes in potash mining 血清中的俱乐部细胞蛋白(CC16)是钾盐开采中柴油废气和爆破烟尘造成小气道上皮损伤的效应标志物
IF 3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-18 DOI: 10.1007/s00420-023-02035-x

Abstract

Objective

The effect marker club cell protein (CC16) is secreted by the epithelium of the small respiratory tract into its lumen and passes into the blood. Increased amounts of CC16 in serum are observed during acute epithelial lung injury due to air pollutants. CC16 in serum was determined as part of this cross-sectional study in underground potash miners on acute and chronic health effects from exposures to diesel exhaust and blasting fumes.

Methods

Nitrogen oxides, carbon monoxide, and diesel particulate matter were measured in 672 workers at a German potash mining site on a person-by-person basis over an early shift or midday shift, together with CC16 serum concentrations before and after the respective shift. CC16 concentrations and CC16 shift-differences were evaluated with respect to personal exposure measurements and other quantitative variables by Spearman rank correlation coefficients. CC16 shift-differences were modeled using multiple linear regression. Above-ground workers as reference group were compared to the exposed underground workers.

Results

Serum concentrations of CC16 were influenced by personal characteristics such as age, smoking status, and renal function. Moreover, they showed a circadian rhythm. While no statistically significant effects of work-related exposure on CC16 concentrations were seen in never smokers, such effects were evident in current smokers.

Conclusion

The small airways of current smokers appeared to be vulnerable to the combination of measured work-related exposures and individual exposure to smoking. Therefore, as health protection of smokers exposed to diesel exhaust and blasting fumes, smoking cessation is strongly recommended.

摘要 目的 小呼吸道上皮细胞向腔内分泌效应标志物俱乐部细胞蛋白(CC16)并进入血液。在空气污染物导致急性肺上皮损伤时,可观察到血清中的 CC16 含量增加。作为这项横断面研究的一部分,对地下钾盐矿工进行了血清中 CC16 的测定,以了解接触柴油废气和爆破烟雾对健康造成的急性和慢性影响。 方法 在德国的一个钾盐采矿场,对早班或中班的 672 名工人逐人测量了氮氧化物、一氧化碳和柴油微粒物质,并测量了各班前后的 CC16 血清浓度。通过斯皮尔曼等级相关系数评估了 CC16 浓度和 CC16 班次差异与个人暴露测量值和其他定量变量之间的关系。CC16 班次差异采用多元线性回归建模。作为参照组的地面工人与暴露在地下的工人进行了比较。 结果 血清中的 CC16 浓度受年龄、吸烟状况和肾功能等个人特征的影响。此外,它们还呈现出昼夜节律。虽然从未吸烟者的工作相关暴露对 CC16 浓度没有明显的统计学影响,但当前吸烟者的工作相关暴露对 CC16 浓度有明显影响。 结论 当前吸烟者的小气道似乎很容易受到工作相关暴露和个人吸烟暴露的共同影响。因此,为了保护暴露在柴油机废气和爆破烟雾中的吸烟者的健康,强烈建议戒烟。
{"title":"Club cell protein (CC16) in serum as an effect marker for small airway epithelial damage caused by diesel exhaust and blasting fumes in potash mining","authors":"","doi":"10.1007/s00420-023-02035-x","DOIUrl":"https://doi.org/10.1007/s00420-023-02035-x","url":null,"abstract":"<h3>Abstract</h3> <span> <h3>Objective</h3> <p>The effect marker club cell protein (CC16) is secreted by the epithelium of the small respiratory tract into its lumen and passes into the blood. Increased amounts of CC16 in serum are observed during acute epithelial lung injury due to air pollutants. CC16 in serum was determined as part of this cross-sectional study in underground potash miners on acute and chronic health effects from exposures to diesel exhaust and blasting fumes.</p> </span> <span> <h3>Methods</h3> <p>Nitrogen oxides, carbon monoxide, and diesel particulate matter were measured in 672 workers at a German potash mining site on a person-by-person basis over an early shift or midday shift, together with CC16 serum concentrations before and after the respective shift. CC16 concentrations and CC16 shift-differences were evaluated with respect to personal exposure measurements and other quantitative variables by Spearman rank correlation coefficients. CC16 shift-differences were modeled using multiple linear regression. Above-ground workers as reference group were compared to the exposed underground workers.</p> </span> <span> <h3>Results</h3> <p>Serum concentrations of CC16 were influenced by personal characteristics such as age, smoking status, and renal function. Moreover, they showed a circadian rhythm. While no statistically significant effects of work-related exposure on CC16 concentrations were seen in never smokers, such effects were evident in current smokers.</p> </span> <span> <h3>Conclusion</h3> <p>The small airways of current smokers appeared to be vulnerable to the combination of measured work-related exposures and individual exposure to smoking. Therefore, as health protection of smokers exposed to diesel exhaust and blasting fumes, smoking cessation is strongly recommended.</p> </span>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"1 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138742673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Archives of Occupational and Environmental Health
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