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Time trend of urine metal levels in preschool children in the electronic waste recycling area and its association with hemoglobin levels. 电子垃圾回收区学龄前儿童尿金属水平的时间趋势及其与血红蛋白水平的关系
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-09-26 DOI: 10.1007/s00420-025-02166-3
Rongyi Kang, Jieting Chen, Kaihui Li, Rui Sun, Jian Zhang, Chenxu Dai, Xijin Xu, Bo Xie, William W Au, Lei Tan, Xia Huo

Objectives: E-waste recycling releases toxic metals into the environment, posing a considerable threat to children's health. Since 2012, China has implemented strict regulations and import controls on the e-waste industry. This study investigates the six-year trends of urinary metal levels and health risks in preschool children, including exposure levels, health risks, and association with hemoglobin.

Methods: A cross-sectional survey was conducted among 762 preschool children in Guiyu, China. We measured levels of 20 urinary metals and hemoglobin levels. To explore the independent and joint associations between metals and hemoglobin, multiple linear regression and Bayesian kernel machine regression models were used.

Results: Most metals decreased significantly over the period, but some metals remained relatively constant or even increased. Among the metals, lead may be a potential biomarker for e-waste control. The Hazard Index of four metals (nickel, arsenic, cadmium, and lead) exceeded 1 for 98.3% of children. The carcinogenic risk of nickel and arsenic exceeded the threshold for every child and 99.1% of children, respectively. Urinary metal and excretion levels were higher in female. Single metal and mixture metal exposures were significantly correlated with hemoglobin levels and highlight the gender-specific associations.

Conclusions: Urinary metal levels showed a significant downward trend over time under e-waste control, but the risks from nickel and arsenic remain concerning. Female children face higher risks from metal exposure and elevated hemoglobin levels.

目标:电子废物回收释放有毒金属到环境中,对儿童健康构成相当大的威胁。自2012年以来,中国对电子垃圾行业实施了严格的监管和进口管制。本研究调查了学龄前儿童尿中金属含量与健康风险的六年趋势,包括暴露水平、健康风险及其与血红蛋白的关系。方法:对贵玉县762名学龄前儿童进行横断面调查。我们测量了20种尿液金属和血红蛋白的含量。为了探索金属与血红蛋白之间的独立关联和联合关联,我们使用了多元线性回归和贝叶斯核机回归模型。结果:大多数金属在此期间明显下降,但有些金属保持相对稳定甚至增加。在这些金属中,铅可能是控制电子垃圾的潜在生物标志物。98.3%的儿童镍、砷、镉、铅四种金属的危害指数超过1。镍和砷的致癌风险分别超过了每个儿童和99.1%儿童的阈值。女性的尿金属和排泄水平较高。单一金属和混合金属暴露与血红蛋白水平显著相关,并突出了性别特异性关联。结论:在电子垃圾控制下,随着时间的推移,尿金属水平呈显著下降趋势,但镍和砷的风险仍然令人担忧。女性儿童因金属接触和血红蛋白水平升高而面临更高的风险。
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引用次数: 0
Prevalence, subtypes, and risk factors of noise-Induced hearing loss in high-risk occupations: a cross-sectional study in Ningbo. 宁波市高危职业噪声性听力损失流行、亚型及危险因素的横断面研究
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-11-24 DOI: 10.1007/s00420-025-02184-1
Fanfu Zeng, Xinning Gao, Guochuan Mao, Huayun Yi, Renhai Chen, Shangshu Yan

Objectives: This study aimed to determine the prevalence of hearing loss among welders, grinders, and stampers in a district of Ningbo City, identify distinct subtypes of hearing loss, and explore associated risk factors.

Methods: A cross-sectional analysis was conducted using occupational health examination records and on-site environmental monitoring data from enterprises in a district of Ningbo City in 2023. A data-driven clustering approach with a Gaussian mixture model, was used to identify subtypes of hearing loss. Mixed-effects logistic regression was used to assess factors associated with hearing loss.

Results: The prevalence of hearing loss was 54.24% among welders (n = 695), 58.95% among grinders (n = 497), and 64.36% among stampers (n = 390). Increased age, male sex, high noise exposure, and employment within the Construction and Related Services were significant risk factors. Three subtypes of hearing loss were identified: Class 1 (mild, flat threshold elevation at 4-6 kHz), Class 2 (steep threshold elevation at 3-6 kHz), and Class 3 (elevation in speech-frequency ranges). Class 2 was the most prevalent and showed the strongest association with occupational noise exposure.

Conclusion: Hearing loss is common among welders, grinders, and stampers, with stampers being the most affected. Class 2 audiometric pattern was consistent with noise - induced hearing loss. These findings highlight the need for targeted preventive measures in high-risk occupational settings.

目的:本研究旨在确定宁波市某地区焊工、磨工和冲压工中听力损失的患病率,识别不同的听力损失亚型,并探讨相关的危险因素。方法:对宁波市某区企业2023年职业健康检查记录和现场环境监测数据进行横断面分析。使用高斯混合模型的数据驱动聚类方法来识别听力损失亚型。使用混合效应逻辑回归评估与听力损失相关的因素。结果:焊工(n = 695)、磨工(n = 497)和冲压工(n = 390)的听力损失患病率分别为54.24%、58.95%和64.36%。年龄增加、男性、接触高噪音和在建筑及相关服务行业工作是显著的危险因素。听力损失分为三种亚型:1类(轻度,4-6 kHz的平坦阈值升高),2类(3-6 kHz的陡峭阈值升高)和3类(语音频率范围升高)。2级是最普遍的,并显示出最强的相关性与职业噪声暴露。结论:听力损失在焊工、磨工和冲压工中普遍存在,其中冲压工受影响最大。二级听力学模式与噪声性听力损失一致。这些发现强调了在高风险职业环境中采取有针对性的预防措施的必要性。
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引用次数: 0
An increased risk of spontaneous abortion, congenital anomalies, and stillbirth among women occupationally exposed to anaesthetic gases: a meta-analysis of observational studies. 职业暴露于麻醉气体的妇女自然流产、先天性异常和死产的风险增加:一项观察性研究的荟萃分析
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-11-17 DOI: 10.1007/s00420-025-02182-3
Priya Kumar, Marie-Pascale Lehucher-Michel, Anderson Loundou, Fabienne Bregeon, Françoise Martin, Mouloud Bouhadfane

Purpose: The aim of this meta-analysis was to evaluate the risk of spontaneous abortions, congenital anomalies, and stillbirths among women professionally exposed to anaesthetic gases.

Methods: This study was registered in the International Prospective Register of Systematic Reviews (PROSPERO), and we followed the PRISMA 2020 checklist to develop the study protocol. A systematic search was conducted in PubMed using specific keywords to identify observational studies involving women professionally exposed to anaesthetic gases. Data were extracted and analysed using a random-effects model.

Results: A total of 32 studies were included, involving 155,437 healthcare professionals exposed to anaesthetic gases. The analysis revealed an increased risk of spontaneous abortions (OR = 1.47; 95% CI [1.19-1.81]), congenital anomalies (OR = 1.37; 95% CI [1.09-1.73]), and stillbirths (OR = 1.43; 95% CI: [1.09-1.86]) among these women. The risks varied across different professions and countries, with moderate heterogeneity observed in the analyses.

Conclusion: This study confirms an elevated risk of spontaneous abortions, congenital anomalies, and stillbirths in women professionally exposed to anaesthetic gases. These findings highlight the need for preventive measures to minimize exposure and underscore the importance of further research to clarify the risks and develop effective strategies.

Registration: International prospective register of systematic reviews; registration number: CRD42023450226.

目的:本荟萃分析的目的是评估专业接触麻醉气体的妇女发生自然流产、先天性异常和死产的风险。方法:本研究已在国际前瞻性系统评价登记册(PROSPERO)上注册,我们遵循PRISMA 2020清单制定研究方案。在PubMed中进行了系统的搜索,使用特定的关键词来识别涉及专业接触麻醉气体的女性的观察性研究。数据提取和分析使用随机效应模型。结果:共纳入32项研究,涉及155,437名接触麻醉气体的医护人员。分析显示,这些妇女发生自然流产(OR = 1.47; 95% CI[1.19-1.81])、先天性畸形(OR = 1.37; 95% CI[1.09-1.73])和死产(OR = 1.43; 95% CI:[1.09-1.86])的风险增加。风险在不同的职业和国家之间存在差异,分析中观察到适度的异质性。结论:本研究证实,专业接触麻醉气体的妇女发生自然流产、先天性异常和死胎的风险较高。这些发现强调需要采取预防措施以尽量减少暴露,并强调进一步研究以澄清风险和制定有效战略的重要性。注册:国际前瞻性系统评价注册;注册号:CRD42023450226。
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引用次数: 0
Noise-induced hearing impairments in Iranian airlines pilots: risk factors and occupational comparisons. 伊朗航空公司飞行员噪音引起的听力损伤:风险因素和职业比较。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-09-20 DOI: 10.1007/s00420-025-02170-7
Asghar Akhavan, Mahdieh Hasanalifard, Reyhaneh Abolghasemi

Purpose: After vision, hearing is the most important sensory mechanism for obtaining essential and critical information during flight operations. Pilots are at risk of hearing loss due to exposure to excessive noise which usually causes permanent and incurable hearing damage. This study investigated the hearing status of Iranian pilots and explored the relationship between the severity of their impairment, age, work experience and flight hours.

Methods: In this cross-sectional study, eligible pilots were selected. Demographic information, job characteristics, flight hours and auditory complaints were collected. Subsequently, the pilots underwent hearing tests (Pure tone Audiometry) and the hearing threshold was measured at different frequencies.

Results: the study involved 100 pilots (57 fixed-wing pilots and 43 helicopter pilots) with the mean age of 47.77 ± 7.53 years (28-64 years). The average and standard deviation of work experience in all the studied subjects was equal to 24.84 ± 8.44 years. 55 pilots had no auditory impairments, while 45 were diagnosed with some form of hearing impairment. The findings indicate that older age, longer work experience, and more flight hours are significantly associated with greater hearing impairments. Individuals with any level of hearing impairment (slight to mild) had higher age, more work experience, and flight hours compared to those with normal hearing. Helicopter pilots exhibited higher hearing loss severity across frequencies compared to fixed-wing pilots, with statistically significant differences at 2000 Hz for the left ear and 1000, 2000, and 3000 Hz for the right ear. The comparison between the two ears showed that the hearing threshold in any of the flight devices (fixed wing or helicopter), in any of the investigated frequencies, has no significant difference between the left and right ears.

Conclusion: Exposure to loud noise during flights can significantly impact the hearing of pilots. The severity of hearing loss in helicopter pilots is higher across all frequencies compared to fixed-wing pilots. Increased age, work experience, and flight hours are significantly associated with higher severity of hearing loss in both ears. Regular auditory assessments for pilots, especially helicopter pilots, are essential for early detection and monitoring of noise-induced hearing loss.

目的:在飞行操作中,听觉是继视觉之后最重要的获取关键信息的感觉机制。飞行员有听力损失的风险,因为暴露在过度的噪音中,这通常会导致永久性和无法治愈的听力损伤。本研究对伊朗飞行员的听力状况进行调查,探讨其听力损伤程度与年龄、工作经验和飞行时数之间的关系。方法:在横断面研究中,选择符合条件的飞行员。收集了人口统计信息、工作特征、飞行时数和听觉投诉。随后,飞行员进行了听力测试(纯音测听),并测量了不同频率下的听力阈值。结果:共纳入100名飞行员,其中固定翼飞行员57名,直升机飞行员43名,平均年龄47.77±7.53岁(28-64岁)。所有研究对象工作经验的平均值和标准差为24.84±8.44年。55名飞行员没有听觉障碍,而45名飞行员被诊断患有某种形式的听力障碍。研究结果表明,年龄较大、工作经验较长、飞行时间较长与听力损伤程度显著相关。与听力正常的人相比,任何程度的听力障碍(轻微到轻度)的人都有更高的年龄、更多的工作经验和飞行时间。与固定翼飞行员相比,直升机飞行员在不同频率下表现出更高的听力损失严重程度,在左耳2000赫兹和右耳1000、2000和3000赫兹的频率上有统计学上的显著差异。两只耳朵之间的比较表明,在任何一种飞行设备(固定翼或直升机)中,在任何一种调查频率下,左耳和右耳的听力阈值没有显著差异。结论:飞行过程中暴露在大噪音环境中会显著影响飞行员的听力。与固定翼飞机飞行员相比,直升机飞行员听力损失的严重程度在所有频率上都更高。年龄、工作经验和飞行时间的增加与双耳听力损失的严重程度显著相关。定期对飞行员,特别是直升机飞行员进行听力评估,对于早期发现和监测噪音引起的听力损失至关重要。
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引用次数: 0
Air pollution and tuberculosis incidence in Vietnam: short- and long-term effects from a provincial-level study. 越南的空气污染和结核病发病率:一项省级研究的短期和长期影响。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-11-27 DOI: 10.1007/s00420-025-02186-z
Minh Khac Nguyen, Tuyet Thi Nguyen, Ardeshir Sepehri

Purpose: Tuberculosis (TB) remains a major public health challenge in many low- and middle-income countries, where environmental pollution and uneven policy implementation may further exacerbate disease transmission. This study aims to assesss the short and long-term impacts of environmental factors, particularly fine particulate matter (PM2.5), and TB prevention policies on new TB incidence in Vietnam.

Methods: Panel data from 63 provinces from 2005 to 2023 were analyzed using the SYS-GMM model to estimate the effects of PM2.5, temperature, per capita income, provincial government health expenditure, and the government's National Strategy for TB Prevention of 2014 on TB incidence. Long-term effects were also analyzed using long-term multipliers.

Results: PM2.5 had a statistically significant positive effect on TB incidence, consistent with prior findings that fine particulate matter damages respiratory defenses and increases infection risk. The long-term multiplier of PM2.5 was even higher, indicating cumulative effects over time. Temperature was also positively correlated with the incidence of TB, while per capita income and health expenditure were negatively associated with TB incidence. The long-term impact of income was stronger than the short-term effect, highlighting the growing health benefits of economic development. The government's National Strategy for TB Prevention of 2014 was found to be statistically insignificant.

Conclusion: Air pollution significantly increases TB incidence in Vietnam in the short and long term. In the context of climate change and persistent pollution, combining environmental and TB prevention strategies is essential to achieving the goal of TB elimination.

在许多低收入和中等收入国家,结核病仍然是一项重大的公共卫生挑战,在这些国家,环境污染和政策执行不平衡可能进一步加剧疾病传播。本研究旨在评估环境因素,特别是细颗粒物(PM2.5)和结核病预防政策对越南新发结核病发病率的短期和长期影响。方法:采用SYS-GMM模型对2005 - 2023年63个省份的面板数据进行分析,估计PM2.5、温度、人均收入、省级政府卫生支出和政府2014年国家结核病预防战略对结核病发病率的影响。还使用长期乘数分析了长期影响。结果:PM2.5对结核病发病率有统计学上显著的正向影响,与先前的研究结果一致,即细颗粒物损害呼吸防御,增加感染风险。PM2.5的长期乘数甚至更高,表明随着时间的推移会产生累积效应。气温与结核病发病率呈正相关,而人均收入和卫生支出与结核病发病率呈负相关。收入的长期影响强于短期影响,突出表明经济发展对健康的益处越来越大。2014年政府的国家结核病预防战略在统计上是微不足道的。结论:空气污染在短期和长期内显著增加越南结核病发病率。在气候变化和持续污染的背景下,将环境和结核病预防战略相结合对于实现消除结核病的目标至关重要。
{"title":"Air pollution and tuberculosis incidence in Vietnam: short- and long-term effects from a provincial-level study.","authors":"Minh Khac Nguyen, Tuyet Thi Nguyen, Ardeshir Sepehri","doi":"10.1007/s00420-025-02186-z","DOIUrl":"10.1007/s00420-025-02186-z","url":null,"abstract":"<p><strong>Purpose: </strong>Tuberculosis (TB) remains a major public health challenge in many low- and middle-income countries, where environmental pollution and uneven policy implementation may further exacerbate disease transmission. This study aims to assesss the short and long-term impacts of environmental factors, particularly fine particulate matter (PM<sub>2.5</sub>), and TB prevention policies on new TB incidence in Vietnam.</p><p><strong>Methods: </strong>Panel data from 63 provinces from 2005 to 2023 were analyzed using the SYS-GMM model to estimate the effects of PM<sub>2.5</sub>, temperature, per capita income, provincial government health expenditure, and the government's National Strategy for TB Prevention of 2014 on TB incidence. Long-term effects were also analyzed using long-term multipliers.</p><p><strong>Results: </strong>PM<sub>2.5</sub> had a statistically significant positive effect on TB incidence, consistent with prior findings that fine particulate matter damages respiratory defenses and increases infection risk. The long-term multiplier of PM<sub>2.5</sub> was even higher, indicating cumulative effects over time. Temperature was also positively correlated with the incidence of TB, while per capita income and health expenditure were negatively associated with TB incidence. The long-term impact of income was stronger than the short-term effect, highlighting the growing health benefits of economic development. The government's National Strategy for TB Prevention of 2014 was found to be statistically insignificant.</p><p><strong>Conclusion: </strong>Air pollution significantly increases TB incidence in Vietnam in the short and long term. In the context of climate change and persistent pollution, combining environmental and TB prevention strategies is essential to achieving the goal of TB elimination.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"1023-1035"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145633155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational noise exposure and its effects on hearing threshold shifts and otolithic vestibular functions in male workers. 职业性噪声暴露及其对男性工人听阈变化和耳石前庭功能的影响。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-11-20 DOI: 10.1007/s00420-025-02178-z
Tzu-Yin Kuo, Chen-Wei Chang
{"title":"Occupational noise exposure and its effects on hearing threshold shifts and otolithic vestibular functions in male workers.","authors":"Tzu-Yin Kuo, Chen-Wei Chang","doi":"10.1007/s00420-025-02178-z","DOIUrl":"10.1007/s00420-025-02178-z","url":null,"abstract":"","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"957-972"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145563674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extreme temperatures, recent warming and seasonal influenza-linking human exposures to respiratory health in southern Germany. 极端温度、最近的变暖和季节性流感使德国南部人类暴露于呼吸系统健康。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-11-22 DOI: 10.1007/s00420-025-02179-y
Matteo Boser, Daria Luschkova, Monika Seemann, Claudia Traidl-Hoffmann, Maria P Plaza

Purpose: In the context of climate change, extreme ambient temperatures pose a major threat to human health. This study aims to provide detailed insights into how extreme temperatures and potential confounders affect respiratory morbidity.

Methods: We employed a 14-year time series analysis (2006-2019) in southern Germany, applying penalized distributed lag non-linear models to estimate exposure-response relationships between extreme temperatures and respiratory health outcomes, considering emergency outpatient treatments and hospital admissions at the emergency department of the University Hospital Augsburg. We thereby explored the roles of relative humidity and seasonal influenza as potential confounders and vulnerabilities related to age and gender.

Results: We found significantly elevated relative risks (RRs) for the short-term cumulative effect (Lag: 0-3 days) of extreme heat and the long-term cumulative effect (Lag: 0-21 days) of extreme cold on outpatient treatments and hospital admissions. Seasonal influenza was identified as a significant confounder, with attributable fractions comparable to those of cold temperatures. A sub-period analysis (2006-2012 and 2013-2019) revealed a correlation between the recent rise in temperature and the strong increase in the estimated short-term cumulative effect of extreme heat on hospital admissions (2006-2012, RR: 1.08 (95%CI [0.91, 1.27]) vs. 2013-2019, RR: 1.32 (95%CI [1.15, 1.51]).

Conclusion: Our study demonstrated that extreme temperatures significantly affect respiratory morbidity, with notable influences from seasonal influenza. Sub-period analysis indicated that rising temperatures are already translating into measurable effects on respiratory health, foreshadowing the potentially devastating impacts of global warming on human health. Our results thereby provide highly relevant insights to support targeted public healthcare interventions.

目的:在气候变化的背景下,极端环境温度对人类健康构成重大威胁。这项研究旨在提供关于极端温度和潜在混杂因素如何影响呼吸道疾病的详细见解。方法:我们在德国南部采用了14年的时间序列分析(2006-2019),应用惩罚分布滞后非线性模型来估计极端温度与呼吸健康结果之间的暴露-反应关系,同时考虑了奥格斯堡大学医院急诊科的急诊门诊治疗和住院情况。因此,我们探讨了相对湿度和季节性流感作为潜在混杂因素的作用,以及与年龄和性别相关的脆弱性。结果:我们发现极热的短期累积效应(滞后0-3天)和极冷的长期累积效应(滞后0-21天)对门诊治疗和住院的相对风险(rr)显著升高。季节性流感被确定为一个重要的混杂因素,其归因比例与低温相当。一项分期分析(2006-2012年和2013-2019年)显示,近期气温上升与极端高温对住院人数的短期累积效应的强劲增加之间存在相关性(2006-2012年,RR: 1.08 (95%CI[0.91, 1.27]),而2013-2019年,RR: 1.32 (95%CI[1.15, 1.51])。结论:我们的研究表明极端温度对呼吸道疾病有显著影响,其中季节性流感的影响显著。分时期分析表明,气温上升已经转化为对呼吸系统健康的可测量影响,预示着全球变暖对人类健康的潜在破坏性影响。因此,我们的结果为支持有针对性的公共卫生保健干预提供了高度相关的见解。
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引用次数: 0
Shift work and metabolic dysfunction-associated steatotic liver disease: a systematic review of observational studies. 轮班工作和代谢功能障碍相关的脂肪变性肝病:一项观察性研究的系统综述
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-09-17 DOI: 10.1007/s00420-025-02171-6
Bingya Ma, Yihang Fan, Wenjun Fan

Objective: Shift work disrupts the circadian rhythm and may increase the risk of metabolic disorders, including nonalcoholic fatty liver disease, recently redefined as metabolic dysfunction-associated steatotic liver disease (MASLD), and its progressive form, metabolic dysfunction-associated steatohepatitis. This systematic review aimed to synthesize observational studies on the association between shift work and MASLD.

Methods: A comprehensive literature search was conducted in the PubMed, Scopus, and Web of Science databases up to November 25, 2024, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data were extracted and summarized based on pre-specified inclusion and exclusion criteria. The National Institutes of Health quality assessment tool was used to evaluate the quality of the included studies. Both data extraction and quality assessment were conducted independently by two authors, with disagreements resolved through consensus.

Results: Nine studies met the criteria and were included in the review, including various occupational groups. Most studies reported a positive association between shift work and MASLD, with stronger effects observed in workers exposed to long-term or frequent shift work. Subgroup and interaction analyses suggested that gender, age, lifestyle, chronotype, and occupational factors may modify this association, while body mass index was identified as a potential mediator of the relationship between shift work and MASLD. However, methodological issues, such as imprecise exposure and outcome measurements and a lack of time-varying analysis, limit causal interpretation.

Conclusion: The systematic review supports an association between shift work and increased MASLD risk. Further prospective studies with rigorous designs and diverse populations, as well as stronger mechanistic evidence, are needed to establish a causal link between shift work and MASLD.

目的:轮班工作扰乱昼夜节律,可能增加代谢紊乱的风险,包括非酒精性脂肪性肝病,最近被重新定义为代谢功能障碍相关的脂肪性肝病(MASLD),及其进行性形式,代谢功能障碍相关的脂肪性肝炎。本系统综述旨在综合轮班工作与MASLD之间关系的观察性研究。方法:在PubMed、Scopus和Web of Science数据库中进行全面的文献检索,截止到2024年11月25日,遵循系统评价和元分析指南的首选报告项目。根据预先规定的纳入和排除标准提取和汇总数据。采用美国国立卫生研究院质量评估工具评价纳入研究的质量。数据提取和质量评估均由两位作者独立进行,分歧通过共识解决。结果:9项研究符合标准并纳入综述,包括不同的职业群体。大多数研究报告轮班工作与MASLD之间存在正相关,在长期或频繁轮班工作的工人中观察到更强的影响。亚组分析和相互作用分析表明,性别、年龄、生活方式、睡眠类型和职业因素可能会改变这种关联,而体重指数被认为是倒班工作与MASLD之间关系的潜在中介。然而,方法上的问题,如不精确的暴露和结果测量以及缺乏时变分析,限制了因果解释。结论:系统评价支持轮班工作与MASLD风险增加之间的关联。进一步的前瞻性研究需要严格的设计和多样化的人群,以及更有力的机制证据,以建立轮班工作和MASLD之间的因果关系。
{"title":"Shift work and metabolic dysfunction-associated steatotic liver disease: a systematic review of observational studies.","authors":"Bingya Ma, Yihang Fan, Wenjun Fan","doi":"10.1007/s00420-025-02171-6","DOIUrl":"10.1007/s00420-025-02171-6","url":null,"abstract":"<p><strong>Objective: </strong>Shift work disrupts the circadian rhythm and may increase the risk of metabolic disorders, including nonalcoholic fatty liver disease, recently redefined as metabolic dysfunction-associated steatotic liver disease (MASLD), and its progressive form, metabolic dysfunction-associated steatohepatitis. This systematic review aimed to synthesize observational studies on the association between shift work and MASLD.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in the PubMed, Scopus, and Web of Science databases up to November 25, 2024, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data were extracted and summarized based on pre-specified inclusion and exclusion criteria. The National Institutes of Health quality assessment tool was used to evaluate the quality of the included studies. Both data extraction and quality assessment were conducted independently by two authors, with disagreements resolved through consensus.</p><p><strong>Results: </strong>Nine studies met the criteria and were included in the review, including various occupational groups. Most studies reported a positive association between shift work and MASLD, with stronger effects observed in workers exposed to long-term or frequent shift work. Subgroup and interaction analyses suggested that gender, age, lifestyle, chronotype, and occupational factors may modify this association, while body mass index was identified as a potential mediator of the relationship between shift work and MASLD. However, methodological issues, such as imprecise exposure and outcome measurements and a lack of time-varying analysis, limit causal interpretation.</p><p><strong>Conclusion: </strong>The systematic review supports an association between shift work and increased MASLD risk. Further prospective studies with rigorous designs and diverse populations, as well as stronger mechanistic evidence, are needed to establish a causal link between shift work and MASLD.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"777-786"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12672679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linking health lifestyle classes to blue-collar workers' participation in worksite health promotion programs in freight transport: a latent class analysis. 将健康生活方式与蓝领工人参与货运工作场所健康促进计划联系起来:潜在阶层分析。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-11-11 DOI: 10.1007/s00420-025-02175-2
Marc A W Damen, Sarah I Detaille, Luuk P van Iperen, Josephine A Engels, Annet H De Lange
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引用次数: 0
Algorithmic management is associated with psychological distress, musculoskeletal pain, and occupational accidents: a cross-sectional study in logistics. 算法管理与心理困扰、肌肉骨骼疼痛和职业事故有关:物流的横断面研究。
IF 2.4 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 Epub Date: 2025-11-18 DOI: 10.1007/s00420-025-02180-5
Karin Hennum Nilsson, Theo Bodin, Pille Strauss, Nuria Matilla-Santander, Kathryn Badarin, Emma Brulin, Carin Håkansta

Objective: Algorithmic Management (AM) is increasingly shaping work environments across various sectors, influencing how tasks are assigned and monitored. While concerns have been raised regarding its potential impact on worker health, empirical evidence remains limited. This study examines the association between level of AM exposure and adverse health outcomes among logistics workers.

Methods: This cross-sectional study used an online survey, targeting logistics workers in Sweden. AM exposure was measured using an 11-item scale capturing aspects such as task allocation, surveillance, and performance monitoring. Health outcomes included psychological distress, musculoskeletal pain, headaches, sleep disturbances, and occupational accidents.

Results: Higher AM exposure was associated with increased prevalence of psychological distress (PR 2·12, 95% CI 1·49-3·02), occupational accidents (PR 1·92, 95% CI 1·22-3·01), headaches (PR 1·68, 95%CI 1·09-2·58), and musculoskeletal pain (PR 1·54, 95% CI 1·23-1·92). Stratified analyses revealed stronger associations for drivers, particularly regarding psychological distress, headaches, and sleep disturbances, while warehouse workers exhibited less consistent patterns.

Conclusions: These findings highlight AM as a potential occupational health hazard, particularly when involving high levels of automated oversight and direction. While AM can enhance efficiency, its impact on worker well-being and public health warrants further attention and potentially mitigation strategies to inform policies that balance technological advancements with worker health protection.

目标:算法管理(AM)正在越来越多地塑造各个部门的工作环境,影响任务的分配和监控方式。虽然人们对其对工人健康的潜在影响表示关切,但经验证据仍然有限。本研究探讨了AM暴露水平与物流工人不良健康结果之间的关系。方法:这项横断面研究采用在线调查,目标是瑞典的物流工作者。AM暴露使用11项量表来测量,包括任务分配、监视和性能监视等方面。健康结果包括心理困扰、肌肉骨骼疼痛、头痛、睡眠障碍和职业事故。结果:较高的AM暴露与心理困扰(PR为2.12,95%CI为1.49 - 3.02)、职业事故(PR为1.92,95%CI为1.22 - 3.01)、头痛(PR为1.68,95%CI为1.09 - 2.58)和肌肉骨骼疼痛(PR为1.54,95%CI为1.23 - 1.92)患病率增加相关。分层分析显示,司机与抑郁有更强的联系,尤其是在心理困扰、头痛和睡眠障碍方面,而仓库工人则表现出不太一致的模式。结论:这些发现强调AM是一种潜在的职业健康危害,特别是当涉及高水平的自动化监督和指导时。虽然增材制造可以提高效率,但它对工人福祉和公共卫生的影响值得进一步关注,并可能制定缓解战略,为平衡技术进步与工人健康保护的政策提供信息。
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引用次数: 0
期刊
International Archives of Occupational and Environmental Health
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