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International Journal of Current Research in Chemistry and Pharmaceutical Sciences最新文献

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The impact of open vs closed suction on cardio- respiratory parameters in mechanically ventilated patients 机械通气患者开放与封闭吸引对心肺参数的影响
Pub Date : 2021-07-30 DOI: 10.22192/ijcrcps.2021.08.07.004
S. Alshahrani, A. A. Qureshi, Premalatha Paulsamy, K. Venkatesan, P. Sethuraj
Suctioning of the endotracheal tube in ventilated patients is one of the ways to maintain the airway open. There arevarious risks associated with this procedure. Suctioning methods that are appropriate for the situation can help to avoid acute problems. The purpose of this study was to compare the effects of open vs closed suction on cardiorespiratory parameters in patients on mechanical ventilations. Patients hospitalized to Neuro-ICU and Medical ICU with ventilator support was studied in a non-randomized clinical trial with a time series study design. Sixty samples were chosen using a convenient sampling procedure, including 30 for open suction and 30 for closed suction. Before and during suction, data such as demographic factors and cardio-respiratory parameters such as respiratory rate, heart rate, mean arterial pressure, and SpO2 were measured. In this study, statistically significant changes (p=0.001) in Mean Arterial Pressure (MAP) and SpO2 were identified when open and closed suction systems were compared. According to the findings, closed suction has a significant favourable impact on cardiopulmonary parameters. Keywords: Cardio Respiratory parameters, mechanical ventilation, SpO2, Mean Arterial Pressure (MAP), opensuction, closed suction
通气患者气管插管的吸引是维持气道通畅的方法之一。与此过程相关的风险有很多。适合这种情况的吸痰方法可以帮助避免急性问题。本研究的目的是比较开放和封闭吸引对机械通气患者心肺参数的影响。本研究采用非随机临床试验,采用时间序列研究设计,对神经重症监护室和内科重症监护室呼吸机支持患者进行研究。使用方便的采样程序选择60个样本,其中30个用于开放吸痰,30个用于封闭吸痰。在抽吸前和抽吸过程中,分别测量人口统计学因素和呼吸频率、心率、平均动脉压、SpO2等心肺参数。在本研究中,当比较开放和封闭吸入系统时,发现平均动脉压(MAP)和SpO2的变化具有统计学意义(p=0.001)。根据研究结果,封闭吸引对心肺参数有显著的有利影响。关键词:心肺参数,机械通气,SpO2,平均动脉压(MAP),开吸,闭吸
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引用次数: 0
Ecosystem cadastre of plant-soil interactions with nonferrous metals 有色金属与植物-土壤相互作用的生态系统地籍
Pub Date : 2021-06-30 DOI: 10.22192/ijcrcps.2021.08.06.003
Chrysanthus Chukwuma
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引用次数: 4
Effect of Solvents on Spectrophotometric Analysis of Carbocisteine by Forming Complex with Ninhydrin 溶剂对茚三酮形成络合物分光光度法测定卡西汀的影响
Pub Date : 2021-05-30 DOI: 10.22192/ijcrcps.2021.08.05.004
A. Ramadan, H. Mandil, A. Marei
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引用次数: 0
The Effects of Green Apple Juice (Pyrus malus L.) on Cholesterol Levels in Guinea Pig (Cavia cobaya) 青苹果汁对豚鼠胆固醇水平的影响
Pub Date : 2020-12-16 DOI: 10.22192/ijcrcps.2020.07.12.003
Fahma Shufyani, Jhon Patar Sinurat, R. Berutu
The chemical compound content of green apple juice was pactin, which wass a group of polysaccharides that can lower cholesterol levels. In addition, there were also several secondary metabolites, including flavonoids, glycosides and triterpenoids. To determine the effect of giving green apple juice on the blood cholesterol levels of guinea pigs treated with hypercholesterolemia by giving food mixed with 15% European chicken egg yolk, 15% goat fat, 20 grams of feed for 6 days. The study was divided into 5 groups (A, a, b, c and S) measured cholesterol levels, group A was given aquadest orally (negative control), groups a, b, c were given green apple juice orally at a dose of 2.03 grams / kg BW, dose 4.06 gram / kg BW, 6.09 gram / kg BW, group S was given 0.01% simvastatin suspension at a dose of 0.775 mg / kg BW orally as a positive control for 14 days. Based on the results of the research tested using statistics, it was obtained that the administration of green apple juice at a dose of 2.03 grams / kg BW, a dose of 4.06 grams / kg BW, a dose of 6.09 grams / kg BW showed that the reduction in cholesterol levels was not significantly different from giving simvastatin 0 suspension. 01% dose 0.775mg / kg BW / day.
青苹果汁的化学成分为酪蛋白,是一组具有降低胆固醇作用的多糖。此外,还含有黄酮类、糖苷类、三萜等次生代谢物。为了确定绿苹果汁对高胆固醇血症豚鼠血液胆固醇水平的影响通过给食物混合15%欧洲鸡蛋蛋黄,15%山羊脂肪,20克饲料6天。研究分为A、A、b、c、S 5组测定胆固醇水平,A组给予阿伐他汀口服(阴性对照),A、b、c组给予青苹果汁,剂量分别为2.03 g / kg BW、4.06 g / kg BW、6.09 g / kg BW, S组给予0.01%辛伐他汀混悬液,剂量为0.775 mg / kg BW,作为阳性对照,口服14 d。根据统计检验的研究结果,得到青苹果汁在2.03 g / kg BW、4.06 g / kg BW、6.09 g / kg BW的剂量下,胆固醇水平的降低与辛伐他汀0混悬液没有显著差异。0.01%剂量0.775mg / kg体重/天。
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引用次数: 0
Voltammetric Analysis of Clopidogrel Bisulphate in Pure Form and Pharmaceutical Formulations Using Hanging Mercury Drop Electrode 悬垂汞滴电极对纯硫酸氯吡格雷及制剂的伏安分析
Pub Date : 2020-09-30 DOI: 10.22192/ijcrcps.2020.07.09.001
A. Ramadan, H. Mandil, N. Ashram
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引用次数: 0
Spectrophotometric Study of Interactions Penicillin G Benzathine With Iodine in Acetonitrile and Formation of Complexes 青霉素G苄星与碘在乙腈中相互作用及配合物形成的分光光度研究
Pub Date : 2020-08-30 DOI: 10.22192/ijcrcps.2020.07.08.001
A. Ramadan, H. Mandil, Jenan Sabouni
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引用次数: 0
Spectrophotometric Determination of Glimepiride in Bulk and Tablet Dosage forms Through Formation Ion-Pair Complex Using Metacresol purple. Metacresol紫色形成离子对络合物分光光度法测定原料药和片剂中格列美脲的含量。
Pub Date : 2020-07-30 DOI: 10.22192/ijcrcps.2020.07.07.003
A. Ramadan, H. Mandil, Souad Zeino
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引用次数: 1
In-vitro and in-vivo anti-hyperglycemic activity of methanolic extract of Arbutus pavarii Pampan and Sarcopoterium spinosum L. growing in Libya 利比亚巴伐利亚杨梅和棘肉赘菌甲醇提取物体内外抗高血糖活性研究
Pub Date : 2020-07-30 DOI: 10.22192/ijcrcps.2020.07.07.001
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引用次数: 0
Development of Gold Electrode Modified With Sodium Diethyldithiocarbamate-Nafion to Determine Selenium (IV) in Bulk and in Dosage Formulations Using Differential Pulse Anodic Stripping Voltammetric Analysis 二乙基二硫代氨基甲酸钠修饰金电极的研制及应用差分脉冲阳极溶出伏安法测定大量和剂量配方中的硒
Pub Date : 2020-07-30 DOI: 10.22192/ijcrcps.2020.07.07.002
A. Ramadan, H. Mandil, Abdulrahman Shikh-Debes
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引用次数: 0
Preparing a New Support From Octadecyl-Modified Aleppo Bentonite and Using it For Determining of Automobile Gasoline Using Gas Chromatography 用十八烷基改性阿勒颇膨润土制备新载体并用气相色谱法测定汽车汽油
Pub Date : 2020-06-30 DOI: 10.22192/ijcrcps.2020.07.06.002
A. Ramadan, Saad Aantakli, Ahmad Birouty
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引用次数: 0
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International Journal of Current Research in Chemistry and Pharmaceutical Sciences
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