H. Shamlou, H. Dehghan, S. Namayandeh, O. Yousefianzadeh, M. Aghabagheri
Background: Heart failure (HF) is a major complication resulting from a variety of heart diseases. HF is an increasingly important issue, whose prevalence has doubled in the last two decades. This is due to increased life expectancy, treatment and prevention of other heart diseases, and increased life expectancy. Promoting self-care through tele homecare is an emerging strategy for managing chronic diseases. Objectives: The purpose of this study is to evaluate tele-care studies in patients with chronic heart failure (CHF). This is based evaluating the types of technologies used for patients in this method, effectiveness, cost-effectiveness and safety of these technologies based on the aspects of health technology assessment. Methods: PubMed, Scopus, Web of Science, Cochrane databases, HTA (Health Technology Assessment), NHS EED (National Health System Economic Evaluation Database), DARE (Database of Abstract of Reviews of Effects), Embase, and (Society for Information Display) SID were searched using medical subject heading (Mesh) keywords. Then, studies were evaluated by two people and disputed by a third party. The quality of the extracted studies was evaluated based on the (Risk of Bias) RoB 2.0 checklist. The difference between the mean and its standard deviation was calculated (which was used as the effect size). To analyze the results, meta-analysis of random effects was performed. In addition, the subgroup and meta-regression analysis were performed to discover possible sources of heterogeneity. Finally, studies were evaluated in terms of Health Problem and Current Use of the Technology (CUR), Description and technical characteristics of technology (TEC), safety (SAF), Clinical effectiveness (EFF), Costs and economic evaluation (ECO) of 9 Aspects of Health Technology Assessment (HTA). Studies were evaluated with respect to the long-distance care in patients with CHF. We approach the method through systematic review and meta-analysis based on the principles of PRISMA-P. This systematic review examined the effectiveness of long-distance care interventions in patients with CHF, compared with conventional care methods. In general, evaluation of studies extracted in this systematic review will try to identify, evaluate and combine the effects of tele-care in patients with HF using meta-analytical methods in the evidence. Evaluating studies conducted in the field of tele-care in patients with CHF will help us to better understand how these methods work in the management of chronic heart disease [effectiveness, safety and cost reduction] and determine which care interventions Distance is more effective in patients with HF based on their characteristics according to clinical outcomes and resource use. Conclusion: The results of this study can be used as a guide to provide valid evidence for the decision of senior managers of the Ministry of Health and large hospitals to use common technologies used in distance care for patients with CHF and oth
背景:心力衰竭(HF)是多种心脏疾病引起的主要并发症。心衰是一个日益重要的问题，其患病率在过去二十年中翻了一番。这是由于预期寿命的延长、其他心脏病的治疗和预防以及预期寿命的延长。通过远程家庭护理促进自我保健是一种管理慢性病的新兴战略。目的:本研究的目的是评估慢性心力衰竭(CHF)患者的远程护理研究。这是基于对该方法中用于患者的技术类型、这些技术的有效性、成本效益和安全性的评估，该评估基于卫生技术评估的各个方面。方法:采用医学主题词Mesh检索PubMed、Scopus、Web of Science、Cochrane、HTA(卫生技术评估)、NHS EED(国家卫生系统经济评价数据库)、DARE(效果评价摘要数据库)、Embase、美国信息显示学会SID等数据库。然后，研究由两个人进行评估，并由第三方进行争议。根据(偏倚风险)RoB 2.0检查表对所提取研究的质量进行评估。计算平均值与其标准差之间的差值(用作效应大小)。为了分析结果，我们对随机效应进行meta分析。此外，还进行了亚组和元回归分析，以发现可能的异质性来源。最后，从健康问题和当前技术使用(CUR)、技术描述和技术特征(TEC)、安全性(SAF)、临床有效性(EFF)、卫生技术评估(HTA)的成本和经济评价(ECO) 9个方面对研究进行评价。研究对慢性心力衰竭患者的远程护理进行了评估。我们通过基于PRISMA-P原则的系统回顾和荟萃分析来接近该方法。本系统综述考察了远程护理干预对慢性心力衰竭患者的有效性，并与传统护理方法进行了比较。总的来说，对本系统综述中提取的研究的评价将尝试使用证据中的荟萃分析方法来识别、评估和结合远程护理对心衰患者的影响。评估在心衰患者远程护理领域进行的研究将有助于我们更好地了解这些方法在慢性心脏病管理中的作用[有效性、安全性和成本降低]，并根据临床结果和资源利用，根据心衰患者的特点确定哪种远程护理干预措施对心衰患者更有效。结论:本研究结果可为卫生部和大型医院高层管理人员在对慢性心力衰竭等慢性疾病患者进行远程医疗时采用常用技术的决策提供有效依据。本研究也将从有效性、安全性、技术和经济成本等方面，对不同类型的远程护理技术在帮助慢性衰竭患者方面所进行的各种研究提供新的认识。
{"title":"Evaluation of telehomecare Studies in Patients with Chronic Heart Failure: A health Technology Assessment Study","authors":"H. Shamlou, H. Dehghan, S. Namayandeh, O. Yousefianzadeh, M. Aghabagheri","doi":"10.18502/ccb.v3i1.10065","DOIUrl":"https://doi.org/10.18502/ccb.v3i1.10065","url":null,"abstract":"Background: Heart failure (HF) is a major complication resulting from a variety of heart diseases. HF is an increasingly important issue, whose prevalence has doubled in the last two decades. This is due to increased life expectancy, treatment and prevention of other heart diseases, and increased life expectancy. Promoting self-care through tele homecare is an emerging strategy for managing chronic diseases. \u0000Objectives: The purpose of this study is to evaluate tele-care studies in patients with chronic heart failure (CHF). This is based evaluating the types of technologies used for patients in this method, effectiveness, cost-effectiveness and safety of these technologies based on the aspects of health technology assessment. \u0000Methods: PubMed, Scopus, Web of Science, Cochrane databases, HTA (Health Technology Assessment), NHS EED (National Health System Economic Evaluation Database), DARE (Database of Abstract of Reviews of Effects), Embase, and (Society for Information Display) SID were searched using medical subject heading (Mesh) keywords. Then, studies were evaluated by two people and disputed by a third party. The quality of the extracted studies was evaluated based on the (Risk of Bias) RoB 2.0 checklist. The difference between the mean and its standard deviation was calculated (which was used as the effect size). To analyze the results, meta-analysis of random effects was performed. In addition, the subgroup and meta-regression analysis were performed to discover possible sources of heterogeneity. Finally, studies were evaluated in terms of Health Problem and Current Use of the Technology (CUR), Description and technical characteristics of technology (TEC), safety (SAF), Clinical effectiveness (EFF), Costs and economic evaluation (ECO) of 9 Aspects of Health Technology Assessment (HTA). Studies were evaluated with respect to the long-distance care in patients with CHF. We approach the method through systematic review and meta-analysis based on the principles of PRISMA-P. This systematic review examined the effectiveness of long-distance care interventions in patients with CHF, compared with conventional care methods. In general, evaluation of studies extracted in this systematic review will try to identify, evaluate and combine the effects of tele-care in patients with HF using meta-analytical methods in the evidence. Evaluating studies conducted in the field of tele-care in patients with CHF will help us to better understand how these methods work in the management of chronic heart disease [effectiveness, safety and cost reduction] and determine which care interventions Distance is more effective in patients with HF based on their characteristics according to clinical outcomes and resource use. \u0000Conclusion: The results of this study can be used as a guide to provide valid evidence for the decision of senior managers of the Ministry of Health and large hospitals to use common technologies used in distance care for patients with CHF and oth","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126578029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farnia Ghanbarveisi, Zeinab Mohseni Afshar, Samira Shiri, Maliheh Dayani, K. Tavakol, M. Naderi, M. Rajati, M. Karami, Fatemeh Rajati
Background: People with diabetes or chronic kidney diseases (CKD) are vulnerable to Covid-19. Our aim in this study was to estimate the fatality rate among people with diabetes or CKD infected by Alpha Covid-19 variant. Methods: The authors searched PubMed, Scopus, and Embase from 1/12/2019 to 13/5/2020 to find studies that reported the fatality rate of Alpha Covid-19 variant among patients with diabetes/renal disease. A Random effects model meta-analysis was used to calculate the pooled case fatality rate (CFR). Then, a subgroup analysis was performed according to the sample size to find possible sources of heterogeneity. Results: In total, 22 papers were studied for diabetes and 10 papers for CKD. The pooled CFR was estimated at 23% (95% CI: 0.18, 0.28) among diabetes patients and 31% (95% CI: 0.16, 0.48) among renal patients. High heterogeneity was observed among the studies (Diabetes: I^2=94%, t^2=0.0173, P<0.01), (CKD: I^2=69%, t^2=0.0457, P<0.01). The subgroup analysis indicated that the sample size had a significant effect on fatality rate estimation. In the diabetes patients, the pooled CFR of Alpha Covid-19 variant was 40% (95% CI: 22%-58%; I^2=91%, t^2=0.0797, P<0.01) among the studies with the sample size of less than 52 hospitalized patients. In the studies with equal or more than 52 patients, the pooled CFR was 14% (95% CI: 11%-17%; I^2=88%, t^2=0.0048, P<0.01). In addition, in renal patients, the pooled CFR was 62% (95% CI: 0.06%-100%; I^2=85%, t^2=0.3745, P<0.01) in the studies with less than six hospitalized patients, and the pooled CFR was 23% (95% CI: 16%-31%; I^2=0%, t^2=0.00, P=0.58) among studies with more than 6 patients. Conclusions: People with either diabetes or CKD and infected with Alpha Covid-19 variant had a higher fatality rate in the general population. More care and vaccination is recommended for these patients. It is recommended that we calculate pooled estimation of the case fatality rate of the other variant of COVID-19 such as Beta, Delta, and Omicron in patients with chronic disease.
{"title":"The Case Fatality Rate of Alpha Covid-19 Variant in Patients with Concurrent Diabetes or Chronic Kidney Disease: A Systematic Review and Meta-analysis","authors":"Farnia Ghanbarveisi, Zeinab Mohseni Afshar, Samira Shiri, Maliheh Dayani, K. Tavakol, M. Naderi, M. Rajati, M. Karami, Fatemeh Rajati","doi":"10.18502/ccb.v3i1.9712","DOIUrl":"https://doi.org/10.18502/ccb.v3i1.9712","url":null,"abstract":"Background: People with diabetes or chronic kidney diseases (CKD) are vulnerable to Covid-19. Our aim in this study was to estimate the fatality rate among people with diabetes or CKD infected by Alpha Covid-19 variant. \u0000Methods: The authors searched PubMed, Scopus, and Embase from 1/12/2019 to 13/5/2020 to find studies that reported the fatality rate of Alpha Covid-19 variant among patients with diabetes/renal disease. A Random effects model meta-analysis was used to calculate the pooled case fatality rate (CFR). Then, a subgroup analysis was performed according to the sample size to find possible sources of heterogeneity. \u0000Results: In total, 22 papers were studied for diabetes and 10 papers for CKD. The pooled CFR was estimated at 23% (95% CI: 0.18, 0.28) among diabetes patients and 31% (95% CI: 0.16, 0.48) among renal patients. High heterogeneity was observed among the studies (Diabetes: I^2=94%, t^2=0.0173, P<0.01), (CKD: I^2=69%, t^2=0.0457, P<0.01). The subgroup analysis indicated that the sample size had a significant effect on fatality rate estimation. In the diabetes patients, the pooled CFR of Alpha Covid-19 variant was 40% (95% CI: 22%-58%; I^2=91%, t^2=0.0797, P<0.01) among the studies with the sample size of less than 52 hospitalized patients. In the studies with equal or more than 52 patients, the pooled CFR was 14% (95% CI: 11%-17%; I^2=88%, t^2=0.0048, P<0.01). In addition, in renal patients, the pooled CFR was 62% (95% CI: 0.06%-100%; I^2=85%, t^2=0.3745, P<0.01) in the studies with less than six hospitalized patients, and the pooled CFR was 23% (95% CI: 16%-31%; I^2=0%, t^2=0.00, P=0.58) among studies with more than 6 patients. \u0000Conclusions: People with either diabetes or CKD and infected with Alpha Covid-19 variant had a higher fatality rate in the general population. More care and vaccination is recommended for these patients. It is recommended that we calculate pooled estimation of the case fatality rate of the other variant of COVID-19 such as Beta, Delta, and Omicron in patients with chronic disease.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114224537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Davarinejad, Tahereh Mohammadi Majd, Y. Salimi, M. Abbasi, M. Shirzadi, E. Zereshki
Introduction: Irritable bowel syndrome (IBS) might be associated with psychiatric disorders such as obsessive-compulsive disorder (OCD). This meta-analysis was conducted to compare the rate of OCD among patients with IBS and otherwise healthy controls. Methods: This study was conducted using a meta-analysis approach. International databases including PubMed, Web of Science, and Scopus, as well as the Google Scholar search engine were searched from 1985 to August 2020 to find the related studies. The standardized mean difference (SMD) of OCD between case and control groups was calculated and pooled by using a random-effects model. In addition, meta-regression and sub-group analysis were performed to identify variables that possibly explain the heterogeneity. Results: A total of 5167 patients including 1451 IBS patients for case and 3716 for control group entered 15 related studies were included in the analysis. Based on the results of the random effects analysis, the rate of obsessive-compulsive disorder in IBS patients in case group was higher than the control group (Pooled standardized mean difference, 0.76, I2 = 87.8%; 95% CI, 0.54-0.98; P <0.001). Egger’s (P = 0.083) and Begg’s (P = 0.09) tests did not show significant publication bias. Subgroup analysis also revealed that the type of studies and IBS diagnostic criteria were identified as factors affecting heterogeneity. Conclusion: The present meta-analysis demonstrated that the obsessive-compulsive disorder score in IBS patients was higher than the control group, regardless of subgroup analysis or meta-regression. Due to the significant relationship between these two disorders, psychiatrists and gastroenterologists can provide strategies and techniques for individual or group treatment of obsessive-compulsive disorder in patients with IBS based on the cognitive-behavioral therapy.
{"title":"The Relationship between Obsessive-Compulsive Disorder and Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis","authors":"O. Davarinejad, Tahereh Mohammadi Majd, Y. Salimi, M. Abbasi, M. Shirzadi, E. Zereshki","doi":"10.18502/ccb.v3i1.9410","DOIUrl":"https://doi.org/10.18502/ccb.v3i1.9410","url":null,"abstract":"Introduction: Irritable bowel syndrome (IBS) might be associated with psychiatric disorders such as obsessive-compulsive disorder (OCD). This meta-analysis was conducted to compare the rate of OCD among patients with IBS and otherwise healthy controls. \u0000Methods: This study was conducted using a meta-analysis approach. International databases including PubMed, Web of Science, and Scopus, as well as the Google Scholar search engine were searched from 1985 to August 2020 to find the related studies. The standardized mean difference (SMD) of OCD between case and control groups was calculated and pooled by using a random-effects model. In addition, meta-regression and sub-group analysis were performed to identify variables that possibly explain the heterogeneity. \u0000Results: A total of 5167 patients including 1451 IBS patients for case and 3716 for control group entered 15 related studies were included in the analysis. Based on the results of the random effects analysis, the rate of obsessive-compulsive disorder in IBS patients in case group was higher than the control group (Pooled standardized mean difference, 0.76, I2 = 87.8%; 95% CI, 0.54-0.98; P <0.001). Egger’s (P = 0.083) and Begg’s (P = 0.09) tests did not show significant publication bias. Subgroup analysis also revealed that the type of studies and IBS diagnostic criteria were identified as factors affecting heterogeneity. \u0000Conclusion: The present meta-analysis demonstrated that the obsessive-compulsive disorder score in IBS patients was higher than the control group, regardless of subgroup analysis or meta-regression. Due to the significant relationship between these two disorders, psychiatrists and gastroenterologists can provide strategies and techniques for individual or group treatment of obsessive-compulsive disorder in patients with IBS based on the cognitive-behavioral therapy.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132808157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahdieh Barzegaran, Atie Sadat Khorasanian, S. Jazayeri, M. Foroughan
Background: According to the world health organization (WHO), in 2019, around 50 million people suffer from dementia, worldwide; and approximately 60% live in low- and middle-income countries. Dementia has physical, psychological, social, and economic effects on dementia sufferers, their caregivers, families, and the community. Objectives: This systematic review investigated the effect of short-term and long-term interventions with grapes and their derivatives on different cognitive functions, such as executive function, memory, attention and language in all people. Methods: Pubmed, Scopus, and Proquest were searched until June 12, 2020 for English studies. Clinical trials in which grapes and its derivatives were considered as an intervention and changes of cognition and its components as an outcome, were selected. Two independent individuals assessed the quality of the articles according to Jadad checklist and extracted the information of the articles with inclusion criteria based on a specific table. The differences were resolved with the discussion and opinion of a third person. Results: Nine Studies (211 individuals) were included in the content analysis, of which 3 studies had short-term intervention and 6 studies had long-term intervention with grape juice, freeze-dried grape powder, and a syrup made from grapes (Enoant Syrup). It can be said that the consumption of grapes and its derivatives improved various cognitive components (such as attention, executive function, immediate spatial memory, learning, and driving skill) between groups. Conclusion: In general, long-term intervention with grapes and their derivatives has led to the improvement of some cognitive functions, but its short-term intervention is not very effective and only 2 studies showed improvement in attention speed. However, the included studies were highly heterogeneous and more research is needed using similar cognitive assessment tools.
{"title":"Effect of Grape and its Derivatives on Cognitive Function: A Systematic Review of Clinical Trials","authors":"Mahdieh Barzegaran, Atie Sadat Khorasanian, S. Jazayeri, M. Foroughan","doi":"10.18502/ccb.v3i1.9177","DOIUrl":"https://doi.org/10.18502/ccb.v3i1.9177","url":null,"abstract":"Background: According to the world health organization (WHO), in 2019, around 50 million people suffer from dementia, worldwide; and approximately 60% live in low- and middle-income countries. Dementia has physical, psychological, social, and economic effects on dementia sufferers, their caregivers, families, and the community. \u0000Objectives: This systematic review investigated the effect of short-term and long-term interventions with grapes and their derivatives on different cognitive functions, such as executive function, memory, attention and language in all people. \u0000Methods: Pubmed, Scopus, and Proquest were searched until June 12, 2020 for English studies. Clinical trials in which grapes and its derivatives were considered as an intervention and changes of cognition and its components as an outcome, were selected. Two independent individuals assessed the quality of the articles according to Jadad checklist and extracted the information of the articles with inclusion criteria based on a specific table. The differences were resolved with the discussion and opinion of a third person. \u0000Results: Nine Studies (211 individuals) were included in the content analysis, of which 3 studies had short-term intervention and 6 studies had long-term intervention with grape juice, freeze-dried grape powder, and a syrup made from grapes (Enoant Syrup). It can be said that the consumption of grapes and its derivatives improved various cognitive components (such as attention, executive function, immediate spatial memory, learning, and driving skill) between groups. \u0000Conclusion: In general, long-term intervention with grapes and their derivatives has led to the improvement of some cognitive functions, but its short-term intervention is not very effective and only 2 studies showed improvement in attention speed. However, the included studies were highly heterogeneous and more research is needed using similar cognitive assessment tools. \u0000 ","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134052198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seyedeh Sarah Mousavi, S. Namayandeh, H. Fallahzadeh, M. Rahmanian, Mehdi Mollahosseini
Background: Almost 90% of people with diabetes have type 2 diabetes and the upward trend of this chronic disease is still ongoing, so that after about four decades, this disease is still one of the top 10 causes of death, while half of these deaths occur in people under 60 years of age. Therefore, prevention is essential and the implementation of the most effective intervention approach is required after recognizing at-risk individuals. This study aimed to evaluate the effect of lifestyle modification interventions and metformin on the prevention of type 2 diabetes and improvement in four risk factors related to diabetes. Methods: The study was conducted by searching PubMed, Scopus, Web of science, and Google Scholar without time and language restrictions. Randomized controlled trials which examined the effect of both lifestyle modification interventions and metformin in a population over the age of 18 years with no history of any type of diabetes were included. After the withdrawal of poor quality studies and those withfollow-up time of less than 6 months, structured review and meta-analysis will be performed to calculate the relative risk of type 2 diabetes incidence and mean difference in weight, body mass index, plasma fasting glucose, and hemoglobin A1c. Data analysis was performed using comprehensive meta-analysis software version 2.2.064. Conclusion: This study will make it possible to choose between two conventional therapeutic approaches (lifestyle modification and metformin) to prevent type 2 diabetes and its impact on four risk factors.
背景:几乎90%的糖尿病患者患有2型糖尿病，并且这种慢性疾病的上升趋势仍在持续，因此在大约四十年后，这种疾病仍然是十大死亡原因之一，而这些死亡中有一半发生在60岁以下的人群中。因此，预防是必不可少的，在认识到有风险的个体后，需要实施最有效的干预方法。本研究旨在评估生活方式改变干预和二甲双胍对预防2型糖尿病和改善与糖尿病相关的四种危险因素的影响。方法:检索PubMed、Scopus、Web of science、谷歌Scholar，不受时间和语言限制。随机对照试验研究了生活方式改变干预和二甲双胍对18岁以上无任何糖尿病病史人群的影响。在剔除质量差的研究和随访时间小于6个月的研究后，进行结构化回顾和荟萃分析，计算2型糖尿病发病率的相对风险以及体重、体重指数、空腹血糖和血红蛋白A1c的平均差异。采用版本为2.2.064的综合元分析软件进行数据分析。结论:本研究将使两种常规治疗方法(生活方式改变和二甲双胍)之间的选择成为可能，以预防2型糖尿病及其对四种危险因素的影响。
{"title":"Comparison of the Effectiveness of Metformin with Lifestyle Modification for the Primary Prevention of Type 2 Diabetes: A Protocol for Systematic Review and Meta-Analysis","authors":"Seyedeh Sarah Mousavi, S. Namayandeh, H. Fallahzadeh, M. Rahmanian, Mehdi Mollahosseini","doi":"10.18502/ccb.v3i1.9176","DOIUrl":"https://doi.org/10.18502/ccb.v3i1.9176","url":null,"abstract":"Background: Almost 90% of people with diabetes have type 2 diabetes and the upward trend of this chronic disease is still ongoing, so that after about four decades, this disease is still one of the top 10 causes of death, while half of these deaths occur in people under 60 years of age. Therefore, prevention is essential and the implementation of the most effective intervention approach is required after recognizing at-risk individuals. This study aimed to evaluate the effect of lifestyle modification interventions and metformin on the prevention of type 2 diabetes and improvement in four risk factors related to diabetes. \u0000Methods: The study was conducted by searching PubMed, Scopus, Web of science, and Google Scholar without time and language restrictions. Randomized controlled trials which examined the effect of both lifestyle modification interventions and metformin in a population over the age of 18 years with no history of any type of diabetes were included. After the withdrawal of poor quality studies and those withfollow-up time of less than 6 months, structured review and meta-analysis will be performed to calculate the relative risk of type 2 diabetes incidence and mean difference in weight, body mass index, plasma fasting glucose, and hemoglobin A1c. Data analysis was performed using comprehensive meta-analysis software version 2.2.064. \u0000Conclusion: This study will make it possible to choose between two conventional therapeutic approaches (lifestyle modification and metformin) to prevent type 2 diabetes and its impact on four risk factors.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122576610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Dehghan, Maryam Morshediam, A. Dehghani, M. Mirzaei, Farhad Fatehi
Background: Diabetes is one of the most serious health challenges of the 21st century. The number of adults with diabetes has roughly tripled in the last 20 years. The increased burden of chronic diseases and scarce health resources compel healthcare systems to make modern patients more self-sufficient by requiring them to play a more active part in the treatment and management of their disease. Tele-home-care is a method of distance intervention through the transmission of electronic data for follow-up, education, prevention, clinical decision-making, and treatment modulation that has a high potential for the population with diabetes. Previous studies have not systematically evaluated the effects of different features of long-distance caregiving on diabetes at different stages of disease severity. Objectives: The present study describes a protocol for a systematic review and meta-analysis for summarizing the evidence comparing telehomecare interventions on diabetes management and its complications. Methods: PubMed, Scopus, ISI Web of Science, Cochrane databases, HTA (Health Technology Assessment), NHS EED (NHS Economic Evaluation Database), DARE (Database of Abstract of Reviews of Effects), Embase, and SID will be searched using medical subject heading (MeSH) keywords. Controlled clinical trials in patients with type 1 diabetes, type 2 diabetes, and gestational diabetes will be selected based on predefined eligibility criteria. The risk of bias in studies will be checked using the JADAD score. The mean difference and its standard deviation will be calculated to be used as effect size. A random-effects meta-analysis was performed to pool the results. Subgroup analysis and meta-regression will be conducted to explore the possible sources of heterogeneity. Conclusion: The systematic review and meta-analysis provided by the results of a systematic review can be useful to endocrinologists, physicians, public health policymakers, and the general population.
背景:糖尿病是21世纪最严重的健康挑战之一。在过去的20年里，成人糖尿病患者的数量大约增加了两倍。慢性病负担的增加和卫生资源的匮乏迫使卫生保健系统通过要求现代患者在疾病的治疗和管理中发挥更积极的作用，使他们更加自给自足。远程家庭护理是一种通过传输电子数据进行随访、教育、预防、临床决策和治疗调节的远程干预方法，对糖尿病患者具有很高的潜力。以往的研究没有系统地评估远程护理的不同特征对糖尿病不同疾病严重程度阶段的影响。目的:本研究描述了一个系统回顾和荟萃分析的方案，以总结比较远程家庭护理干预对糖尿病管理及其并发症的证据。方法:使用医学主题词(MeSH)检索PubMed、Scopus、ISI Web of Science、Cochrane数据库、HTA(卫生技术评估)、NHS EED (NHS经济评估数据库)、DARE(疗效评价摘要数据库)、Embase和SID。1型糖尿病、2型糖尿病和妊娠期糖尿病患者的对照临床试验将根据预先确定的资格标准进行选择。研究中的偏倚风险将使用JADAD评分进行检查。将计算平均差及其标准差，以用作效应大小。进行随机效应荟萃分析以汇总结果。我们将进行亚组分析和元回归来探讨异质性的可能来源。结论:系统评价结果提供的系统评价和荟萃分析对内分泌学家、内科医生、公共卫生政策制定者和普通人群都有一定的参考价值。
{"title":"Effects of Telehomecare Interventions on the Management and Complications of Diabetes Mellitus: Protocol for a Systematic Review and Meta-Analysis","authors":"H. Dehghan, Maryam Morshediam, A. Dehghani, M. Mirzaei, Farhad Fatehi","doi":"10.18502/ccb.v2i2.7394","DOIUrl":"https://doi.org/10.18502/ccb.v2i2.7394","url":null,"abstract":"Background: Diabetes is one of the most serious health challenges of the 21st century. The number of adults with diabetes has roughly tripled in the last 20 years. The increased burden of chronic diseases and scarce health resources compel healthcare systems to make modern patients more self-sufficient by requiring them to play a more active part in the treatment and management of their disease. Tele-home-care is a method of distance intervention through the transmission of electronic data for follow-up, education, prevention, clinical decision-making, and treatment modulation that has a high potential for the population with diabetes. Previous studies have not systematically evaluated the effects of different features of long-distance caregiving on diabetes at different stages of disease severity. \u0000Objectives: The present study describes a protocol for a systematic review and meta-analysis for summarizing the evidence comparing telehomecare interventions on diabetes management and its complications. \u0000Methods: PubMed, Scopus, ISI Web of Science, Cochrane databases, HTA (Health Technology Assessment), NHS EED (NHS Economic Evaluation Database), DARE (Database of Abstract of Reviews of Effects), Embase, and SID will be searched using medical subject heading (MeSH) keywords. Controlled clinical trials in patients with type 1 diabetes, type 2 diabetes, and gestational diabetes will be selected based on predefined eligibility criteria. The risk of bias in studies will be checked using the JADAD score. The mean difference and its standard deviation will be calculated to be used as effect size. A random-effects meta-analysis was performed to pool the results. Subgroup analysis and meta-regression will be conducted to explore the possible sources of heterogeneity. \u0000Conclusion: The systematic review and meta-analysis provided by the results of a systematic review can be useful to endocrinologists, physicians, public health policymakers, and the general population.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124524346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sajjad Bahariniya, F. Madadizadeh, Mohammad Ezati Asar
The article's abstract is not available.
这篇文章的摘要没有。
{"title":"Using Face Masks as a Cheap and Critical Tool in Reducing COVID-19 Spread","authors":"Sajjad Bahariniya, F. Madadizadeh, Mohammad Ezati Asar","doi":"10.18502/ccb.v2i2.7398","DOIUrl":"https://doi.org/10.18502/ccb.v2i2.7398","url":null,"abstract":"The article's abstract is not available. ","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114815151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Hashemi, M. Nobakht, Arezoo Ghazalgoo, Amirhossein Ghadamgah, Elias Kargar-Abarghouei, Maryam Arab Firouzjaei
Coronavirus disease 2019 (COVID-19) is associated with severe multiorgan clinical manifestations. Although respiratory involvement is the predominant manifestation in patients infected with COVID-19, involvement of other organs, such as the nervous system, has also been identified; which highlights the virus' ability to disrupt the organs’ function. There is ample evidence of a nervous system susceptibility to the COVID-19. In this regard, the COVID-19 pandemic effect on psychological health, including insomnia, anxiety, obsessive-compulsive disorder, and depression among health care workers and other high-risk groups has been identified. So far, many studies have examined the psychiatric manifestations in infected patients with COVID-19. Undoubtedly, awareness of these findings can help in the prevention and timely treatment of these patients. This study aimed to review the possible mechanisms of COVID-19 neuroinvasive potential, psychiatric manifestations, and the management of mental disorders in infected patients.
{"title":"Psychiatric Complications in Patients with COVID-19: A Narrative Review","authors":"S. Hashemi, M. Nobakht, Arezoo Ghazalgoo, Amirhossein Ghadamgah, Elias Kargar-Abarghouei, Maryam Arab Firouzjaei","doi":"10.18502/ccb.v2i2.7400","DOIUrl":"https://doi.org/10.18502/ccb.v2i2.7400","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is associated with severe multiorgan clinical manifestations. Although respiratory involvement is the predominant manifestation in patients infected with COVID-19, involvement of other organs, such as the nervous system, has also been identified; which highlights the virus' ability to disrupt the organs’ function. There is ample evidence of a nervous system susceptibility to the COVID-19. In this regard, the COVID-19 pandemic effect on psychological health, including insomnia, anxiety, obsessive-compulsive disorder, and depression among health care workers and other high-risk groups has been identified. So far, many studies have examined the psychiatric manifestations in infected patients with COVID-19. Undoubtedly, awareness of these findings can help in the prevention and timely treatment of these patients. This study aimed to review the possible mechanisms of COVID-19 neuroinvasive potential, psychiatric manifestations, and the management of mental disorders in infected patients.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116529035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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