Background: Social life can be affected by skin condition. Acne Vulgaris (AV) is a multi-factorial skin disorder that affects many people. Several dietary factors are associated with AV. Objectives: Different findings on glycemic indices led us to investigate the effect of the dietary glycemic index (GI) and glycemic load (GL) on AV by a systematic review and meta-analysis. Methods: Observational studies and clinical trials were extracted from PubMed, EMBASE, Scopus, and Google Scholar. The mean ± Standard division (SD) for acne grading in clinical trials and the mean ± SD GI or GL of the diet for observational studies were used for meta-analysis. Results: We found that nine out of 15 studies were eligible for systematic review clinical trials (N = 3) and observational studies (N = 6) designs. The meta-analysis of three studies clinically assessed the effect of GI/GL on acne and showed that a diet with lower GI/GL reduced the acne severity (Hedges’g = -0.91, 95% CI: -1.57, -0.25, P = 0.007). The analysis of six observational studies showed that dietary habit with higher GI might not affect the acne severity in patients with AV (Hedges’g = 0.07, 95%CI: -0.23, 0.38, P = 0.636), but individuals with higher acne severity had a diet with higher GL (Hedges’g = 0.64, 95%CI: 0.01, 1.26, P = 0.045). Conclusions: Diet, as a part of life style, is associated with AV. Adherence to lower GL diet may reduce the severity of AV. Further well-designed clinical trials are required to confirm these results.
{"title":"Low Glycemic Load or Index Diet in Association with Acne Vulgaris: A Systematic Review and Meta-analysis","authors":"Roya Sakhaei, M. Mohsenpour","doi":"10.18502/ccb.v1i1.2869","DOIUrl":"https://doi.org/10.18502/ccb.v1i1.2869","url":null,"abstract":"Background: Social life can be affected by skin condition. Acne Vulgaris (AV) is a multi-factorial skin disorder that affects many people. Several dietary factors are associated with AV. \u0000Objectives: Different findings on glycemic indices led us to investigate the effect of the dietary glycemic index (GI) and glycemic load (GL) on AV by a systematic review and meta-analysis. \u0000Methods: Observational studies and clinical trials were extracted from PubMed, EMBASE, Scopus, and Google Scholar. The mean ± Standard division (SD) for acne grading in clinical trials and the mean ± SD GI or GL of the diet for observational studies were used for meta-analysis. \u0000Results: We found that nine out of 15 studies were eligible for systematic review clinical trials (N = 3) and observational studies (N = 6) designs. The meta-analysis of three studies clinically assessed the effect of GI/GL on acne and showed that a diet with lower GI/GL reduced the acne severity (Hedges’g = -0.91, 95% CI: -1.57, -0.25, P = 0.007). The analysis of six observational studies showed that dietary habit with higher GI might not affect the acne severity in patients with AV (Hedges’g = 0.07, 95%CI: -0.23, 0.38, P = 0.636), but individuals with higher acne severity had a diet with higher GL (Hedges’g = 0.64, 95%CI: 0.01, 1.26, P = 0.045). \u0000Conclusions: Diet, as a part of life style, is associated with AV. Adherence to lower GL diet may reduce the severity of AV. Further well-designed clinical trials are required to confirm these results.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123800013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Functional Gastrointestinal Diseases (FGIDs) impose a huge health burden, and lead to metabolic and mental disorders, impaired social function and productivity, reduced quality of life, higher total mortality and health care cost. Beverages are one of the major components of habitual dietary habits that may influence the symptoms of FGIDs. Objective: The purpose of this study was to review the effect of frequent dietary fluids on common causes of FGIDS including functional dyspepsia (FD), irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD) and functional constipation (FC). Methods: A literature search was done using the following search engines: PubMed, Google Scholar and ISI web of science with the following search terms “beverages”, tea”, “caffeine”, “coffee”, “milk”, “water”, “fruit juice”, “carbonated beverage”, “constipation”, “irritable bowel syndrome”, “gastroesophageal reflux disease”, “dyspepsia”,. Results: In this review, 85 studies were evaluated. It was shown that to higher intakes of caffeinated drinks, fruit juice, milk, soft drinks and carbonated beverages are associated with aggravating symptoms in GERD, IBS and FD. The data on the relation between water consumption with GERD, IBS and FD are limited and inconsistent. However, consumption of fruit juices and water was related to an improvement in constipation. Conclusion: Fluid intake can be effective in the management of FGIDs symptoms. However, further investigation on the role of various fluids consumption on symptoms of FGIDS is required.
背景:功能性胃肠道疾病(fgid)造成巨大的健康负担，导致代谢和精神障碍，社会功能和生产力受损，生活质量下降，总死亡率和医疗保健费用增加。饮料是可能影响fgid症状的习惯性饮食习惯的主要组成部分之一。目的:本研究的目的是回顾频繁饮食液体对FGIDS常见原因的影响，包括功能性消化不良(FD)，肠易激综合征(IBS)，胃食管反流病(GERD)和功能性便秘(FC)。方法:使用以下搜索引擎进行文献检索:PubMed、Google Scholar和ISI web of science，搜索词为“饮料”、“茶”、“咖啡因”、“咖啡”、“牛奶”、“水”、“果汁”、“碳酸饮料”、“便秘”、“肠易激综合征”、“胃食管反流病”、“消化不良”、。结果:本综述共评估了85项研究。研究表明，大量摄入含咖啡因的饮料、果汁、牛奶、软饮料和碳酸饮料与胃反流、肠易激综合征和FD的症状加重有关。关于饮水量与胃食管反流、肠易激综合征和FD之间关系的数据有限且不一致。然而，饮用果汁和水与便秘的改善有关。结论:液体摄入可有效治疗FGIDs症状。然而，需要进一步研究各种液体摄入对FGIDS症状的作用。
{"title":"Fluid Intake and Functional Gastrointestinal Disease: A Narrative Review","authors":"Z. Fallah, G. Ferns, M. Ghayour-Mobarhan","doi":"10.18502/CCB.V1I1.2872","DOIUrl":"https://doi.org/10.18502/CCB.V1I1.2872","url":null,"abstract":"Background: Functional Gastrointestinal Diseases (FGIDs) impose a huge health burden, and lead to metabolic and mental disorders, impaired social function and productivity, reduced quality of life, higher total mortality and health care cost. Beverages are one of the major components of habitual dietary habits that may influence the symptoms of FGIDs. \u0000Objective: The purpose of this study was to review the effect of frequent dietary fluids on common causes of FGIDS including functional dyspepsia (FD), irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD) and functional constipation (FC). Methods: A literature search was done using the following search engines: PubMed, Google Scholar and ISI web of science with the following search terms “beverages”, tea”, “caffeine”, “coffee”, “milk”, “water”, “fruit juice”, “carbonated beverage”, “constipation”, “irritable bowel syndrome”, “gastroesophageal reflux disease”, “dyspepsia”,. \u0000Results: In this review, 85 studies were evaluated. It was shown that to higher intakes of caffeinated drinks, fruit juice, milk, soft drinks and carbonated beverages are associated with aggravating symptoms in GERD, IBS and FD. The data on the relation between water consumption with GERD, IBS and FD are limited and inconsistent. However, consumption of fruit juices and water was related to an improvement in constipation. \u0000Conclusion: Fluid intake can be effective in the management of FGIDs symptoms. However, further investigation on the role of various fluids consumption on symptoms of FGIDS is required.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116968708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Javad Dehqan, S. Negintaji, Farnoosh Mirjalili, R. Bidaki, A. Mohammadi, A. Sahebnasagh, F. Saghafi
Background: Cancer is a global problem and causes lots of deaths across the world. Due to the high cost of manufacturing and developing new drugs, there is more willingness to use medications that may have anti-neoplastic effects. Objectives: Antipsychotic drugs have a long history of clinical use. Currently, there are several reports about the anticancer effects of antipsychotic drugs in different types of malignancies. Methods: In this study, the effects and mechanisms of several antipsychotic drugs on different types of cancer were investigated. The current investigations show that some antipsychotic drugs might inhibit the proliferation of cancer cells and some others can be used to ease the symptoms caused by cancer. Results: The anticancer effects of all antipsychotic drugs haven’t been thoroughly investigated and it is reported that few drugs may reverse the effects and increase the risk of neoplasm. Conclusions: Although some studies have revealed that antipsychotic drugs might beneficially affect cancer cells, high quality clinical trials are still needed to confirm these results.
{"title":"The Relationship between Antipsychotic Medications and Cancer: A Review Article","authors":"Mohammad Javad Dehqan, S. Negintaji, Farnoosh Mirjalili, R. Bidaki, A. Mohammadi, A. Sahebnasagh, F. Saghafi","doi":"10.18502/CCB.V1I1.2871","DOIUrl":"https://doi.org/10.18502/CCB.V1I1.2871","url":null,"abstract":"Background: Cancer is a global problem and causes lots of deaths across the world. Due to the high cost of manufacturing and developing new drugs, there is more willingness to use medications that may have anti-neoplastic effects. \u0000Objectives: Antipsychotic drugs have a long history of clinical use. Currently, there are several reports about the anticancer effects of antipsychotic drugs in different types of malignancies. \u0000Methods: In this study, the effects and mechanisms of several antipsychotic drugs on different types of cancer were investigated. The current investigations show that some antipsychotic drugs might inhibit the proliferation of cancer cells and some others can be used to ease the symptoms caused by cancer. \u0000Results: The anticancer effects of all antipsychotic drugs haven’t been thoroughly investigated and it is reported that few drugs may reverse the effects and increase the risk of neoplasm. Conclusions: Although some studies have revealed that antipsychotic drugs might beneficially affect cancer cells, high quality clinical trials are still needed to confirm these results.","PeriodicalId":138934,"journal":{"name":"Critical Comments in Biomedicine","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114274200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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