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Preventing type 2 diabetes among Indigenous youth: A systematic review of community-based interventions. 在土著青年中预防 2 型糖尿病:基于社区的干预措施系统回顾。
IF 1.3 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 Epub Date: 2024-02-27 DOI: 10.1080/22423982.2024.2320449
Shelley Spurr, Meridith Burles, Shannon Hyslop, Jill Bally, Carol Bullin, Amanda Froehlich Chow, Helen Tootoosis, Sarah Oosman

A systematic review was conducted to assess evidence on effectiveness of community-based interventions promoting wellbeing and prevention of type 2 diabetes (T2D) among Indigenous youth. A convergent, segregated, mixed methods approach was used, with six databases and four grey literature sites searched from inception to May 2022. Articles selected for inclusion were about community-based interventions related to T2D prevention with Indigenous youth that evaluated effectiveness or youth experience published in English. Reference lists were also searched for relevant sources. Seven quantitative research articles met the inclusion and quality assessment criteria. No qualitative articles were identified. The results were synthesised through narrative analysis, while meta-analysis was not possible due to heterogenous study designs. Common foci across interventions included promoting physical wellness, improving physical activity and healthy eating patterns, enhancing knowledge, and psychosocial wellness. Interventions deemed effective addressed multiple areas, were school-based, and operated for at least a year. Findings support multi-strategy, community-based interventions implemented over longer periods of time. However, gaps in research and reporting included the extent to which interventions are culturally informed and based on community-driven priorities. Future research should include Indigenous, mixed and qualitative methods and Indigenous-driven measures of success to better understand effectiveness in alignment with Indigenous worldviews.

我们进行了一项系统性综述,以评估基于社区的干预措施在促进土著青年福祉和预防 2 型糖尿病 (T2D) 方面的有效性。研究采用了聚合、分离、混合的方法,检索了从开始到 2022 年 5 月的 6 个数据库和 4 个灰色文献网站。所选纳入的文章都是以社区为基础、针对原住民青少年预防 T2D 的干预措施,这些干预措施以英语发表,对有效性或青少年的经历进行了评估。此外,还搜索了参考文献列表中的相关资料。七篇定量研究文章符合纳入和质量评估标准。未发现定性文章。研究结果通过叙事分析进行了综合,但由于研究设计不尽相同,因此无法进行荟萃分析。各种干预措施的共同重点包括促进身体健康、改善体育锻炼和健康饮食模式、增强知识和社会心理健康。被认为有效的干预措施涉及多个领域,以学校为基础,至少持续一年。研究结果支持在较长时间内实施多策略、基于社区的干预措施。然而,研究和报告中的不足之处包括干预措施在多大程度上具有文化信息并以社区驱动的优先事项为基础。未来的研究应包括土著、混合和定性方法以及土著驱动的成功衡量标准,以更好地了解与土著世界观相一致的有效性。
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引用次数: 0
COVID-19 and local community resilience in the Westfjords of Iceland. COVID-19 和冰岛西峡湾当地社区的恢复能力。
IF 1.3 4区 医学 Q2 Social Sciences Pub Date : 2024-12-01 Epub Date: 2024-02-07 DOI: 10.1080/22423982.2024.2311966
Lara Johannsdottir, David Cook

Remote Arctic communities have often been depicted as being particularly vulnerable to the challenges of disasters, with their location and lack of infrastructure exacerbating risk. This study explores the characteristics of local resilience in the Arctic using the case study of the communities of the north-western Westfjords. A total of 42 semi-structured interviews were carried out with various community members, seeking to uncover the features of inbuilt resilience that contribute to successes and vulnerabilities. These were transcribed, coded, and categorised in relation to an integrated framework for assessing community resilience in disaster management, which groups topics via the themes of environmental, social, governance, economic, and infrastructure. All themes played a role in the success of local coping strategies, with easy access to the natural environment central to physical and mental well-being. Despite this, vulnerabilities of the community were evident, including insufficient local healthcare workers during a severe COVID-19 outbreak in a care home, the absence of a local quarantine hotel, and insufficient information in foreign languages for non-natives of Iceland. The general trend of following rules and expert advice was demonstrative of strong social capital, with locals trusting those in charge, nationally and locally, to manage the pandemic.

偏远的北极社区往往被描述为特别容易受到灾害的挑战,其地理位置和基础设施的缺乏加剧了风险。本研究以西峡湾(Westfjords)西北部的社区为案例,探讨了北极地区当地抗灾能力的特点。研究人员对不同的社区成员进行了 42 次半结构式访谈,试图揭示导致成功和脆弱性的内在复原力特征。对这些访谈进行了转录、编码,并根据评估灾害管理中社区抗灾能力的综合框架进行了分类,该框架通过环境、社会、治理、经济和基础设施等主题对访谈主题进行了分组。所有主题在当地应对策略的成功中都发挥了作用,而轻松利用自然环境对身心健康至关重要。尽管如此,社区的脆弱性也是显而易见的,包括在一家护理院爆发严重的 COVID-19 疫情时,当地医护人员不足,当地没有隔离酒店,以及对非冰岛本地人而言,外语信息不足。遵守规则和专家建议的普遍趋势显示了强大的社会资本,当地人相信国家和地方的负责人能够控制疫情。
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引用次数: 0
Rabies management structures and challenges in the North in a One Health framework. 在 "一个健康 "框架下,北方的狂犬病管理结构和挑战。
IF 1.3 4区 医学 Q2 Social Sciences Pub Date : 2024-12-01 Epub Date: 2024-02-18 DOI: 10.1080/22423982.2024.2318059
Karsten Hueffer

Rabies is often described as the quintessential One Health problem, linking especially animal health to human health. I examined how rabies is managed in the circumpolar North through semi-structured interviews of key informants in three cases: Alaska, Northwest Territories, and Svalbard. While rabies is controlled at the territorial or state level in the Northwest Territories and Alaska, respectively, the perception of where authority lies in rabies management is less evident in Norway concerning Svalbard than in the other two cases. Respondents generally characterised the working relationship between sectors and scales of governments as positive. However, coordination remains one of the main challenges to rabies management, with harsh environmental conditions and small remote communities adding additional challenges in all three cases. Rabies managers in Svalbard also face unique conditions, such as risks associated with hunting and the particular administrative structure of Svalbard. Due to limited veterinary services in dispersed small and remote communities, dogs present challenges to rabies management in Alaska and the Northwest Territories. Personal relationships are important in disease management across agencies, and the unique challenges in the far North will likely pose challenges in adopting approaches to disease management from temperate climates.

狂犬病通常被描述为典型的 "一体健康 "问题,尤其将动物健康与人类健康联系在一起。我通过对三个地区的主要信息提供者进行半结构化访谈,研究了环北极地区如何管理狂犬病:阿拉斯加、西北地区和斯瓦尔巴群岛。在西北地区和阿拉斯加,狂犬病分别由地区或州一级进行控制,而在挪威和斯瓦尔巴群岛,对狂犬病管理权限的认识则不如其他两个地区明显。受访者普遍认为各部门和各级政府之间的工作关系是积极的。然而,协调仍然是狂犬病管理面临的主要挑战之一,在所有三个案例中,恶劣的环境条件和偏远的小社区又增加了额外的挑战。斯瓦尔巴特群岛的狂犬病管理者还面临着独特的条件,如与狩猎有关的风险和斯瓦尔巴特群岛特殊的行政结构。由于分散在偏远小社区的兽医服务有限,狗给阿拉斯加和西北地区的狂犬病管理带来了挑战。在跨机构的疾病管理中,人际关系非常重要,而遥远的北方地区所面临的独特挑战很可能会给采用温带气候地区的疾病管理方法带来挑战。
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引用次数: 0
Reproducibility and validity of a 45 item food-frequency questionnaire for inuit in Greenland. 针对格陵兰因纽特人的 45 项食物频率问卷的可重复性和有效性。
IF 1.3 4区 医学 Q2 Social Sciences Pub Date : 2024-12-01 Epub Date: 2024-03-26 DOI: 10.1080/22423982.2024.2332008
Peter Bjerregaard, Ingelise Olesen

Since 1993, dietary assessment has been carried out in Greenland as part of recurrent population health surveys. In preparation for the next survey in 2024, 91 participants from the survey in 2018 were selected for a validation study of the Food Frequency Questionnaire (FFQ). The 91 participants were reinterviewed 38-50 months after the first FFQ and invited to complete a food diary. As part of the 2018 survey, blood was analysed for mercury. The food diary was completed by 65 participants. The agreement between the two FFQ interviews was very good for macronutrients and fatty acids (p > 0.20), whereas the calculated intake of mercury was 22% higher in the second FFQ (p = 0.04) due to a higher intake of whale meat and muktuk (whale skin). The agreement between the second FFQ and the food diary was good for local food, imported meat and cakes/sweets/snacks but fruit and vegetables, dairy products, beverages and added sugar were significantly underreported in the food diary. Food items not included in the FFQ were identified from the food diaries. The correlation between the intake of marine mammals and blood mercury was moderate (Spearman's rho = 0.41-0.50; p < 0.0001). The results will inspire future dietary studies in the circumpolar North.

自 1993 年以来,格陵兰一直在开展膳食评估,作为经常性人口健康调查的一部分。为准备 2024 年的下一次调查,从 2018 年的调查中选取了 91 名参与者进行食物频率问卷(FFQ)验证研究。在第一次食物频率问卷调查 38-50 个月后,对这 91 名参与者进行了再次访谈,并邀请他们填写食物日记。作为 2018 年调查的一部分,对血液进行了汞分析。65 名参与者填写了食物日记。在宏量营养素和脂肪酸方面,两次 FFQ 问卷调查之间的一致性非常好(p > 0.20),而在第二次 FFQ 问卷调查中,由于鲸鱼肉和 muktuk(鲸鱼皮)的摄入量较高,计算出的汞摄入量高出 22%(p = 0.04)。在本地食品、进口肉类和蛋糕/甜食/零食方面,第二份家庭食物调查表与食物日记的一致性较好,但在食物日记中,水果和蔬菜、乳制品、饮料和添加糖的报告明显偏低。从食物日记中确定了未列入家庭食物调查表的食物项目。海洋哺乳动物摄入量与血汞之间的相关性适中(Spearman's rho = 0.41-0.50; p
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引用次数: 0
The impacts of the Nutrition North Canada program on the accessibility and affordability of perishable, nutritious foods among eligible communities: a scoping review. 加拿大北部营养计划对合格社区易腐营养食品的可获得性和可负担性的影响:范围界定审查。
IF 1.3 4区 医学 Q2 Social Sciences Pub Date : 2024-12-01 Epub Date: 2024-02-12 DOI: 10.1080/22423982.2024.2313255
Jason Edward Pagaduan, Calin Lazarescu, Eric Vallieres, Kelly Skinner, Alexandra M E Zuckermann, Leanne Idzerda

The Nutrition North Canada (NNC) program, introduced in April 2011 is a federal strategy to improve access to perishable, nutritious foods for remote and isolated communities in northern Canada by subsidising retailers to provide price reductions at the point of purchase. As of March 2023, 123 communities are eligible for the program. To evaluate existing evidence and research on the NNC program to inform policy decisions to improve the effectiveness of NNC. A scoping review of peer-reviewed articles was conducted in ten databases along with a supplemental grey literature search of government and non-government reports published between 2011 and 2022. The search yielded 172 publications for screening, of which 42 were included in the analysis. Narrative thematic evidence synthesis yielded 104 critiques and 341 recommendations of the NNC program across eight themes. The most-identified recommendations focus on transparency, communication, and support for harvesting, hunting, and community food initiatives. This review highlights recommendations informed by the literature to address critiques of the NNC program to improve food security, increase access to perishable and non-perishable items, and support community-based food initiatives among eligible communities. The review also identifies priority areas for future policy directions such as additional support for education initiatives, communication and transparency amidst program changes, and food price regulations.

2011 年 4 月推出的 "加拿大北部营养"(NNC)计划是一项联邦战略,旨在通过补贴零售商在购买点提供降价,改善加拿大北部偏远和孤立社区获得易腐营养食品的机会。截至 2023 年 3 月,共有 123 个社区符合该计划的条件。评估有关 "全国营养计划 "的现有证据和研究,为决策提供信息,以提高 "全国营养计划 "的有效性。我们在 10 个数据库中对同行评审文章进行了范围审查,并对 2011 年至 2022 年间发表的政府和非政府报告进行了补充灰色文献检索。搜索结果共筛选出 172 篇出版物,其中 42 篇被纳入分析。叙事性专题证据综述得出了对新生儿营养计划的 104 条批评意见和 341 条建议,涉及八个主题。最多人认同的建议集中在透明度、沟通以及对收获、狩猎和社区食品计划的支持上。本审查报告重点介绍了根据文献资料提出的建议,这些建议旨在解决对 NNC 计划的批评,以改善粮食安全、增加易腐烂和非易腐烂物品的获取途径,并支持符合条件的社区开展以社区为基础的食品行动。本综述还确定了未来政策方向的优先领域,如对教育倡议的额外支持、计划变化中的沟通和透明度以及食品价格法规。
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引用次数: 0
Personal experiences of living with sucrose intolerance and attitudes towards genetic research in Greenland - a user study. 格陵兰蔗糖不耐症患者的个人生活经历和对基因研究的态度--一项用户研究。
IF 1.3 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 Epub Date: 2024-07-23 DOI: 10.1080/22423982.2024.2383023
Silvia Isidor, Ninna Senftleber, Cecilie Schnoor, Kristine Skoett Pedersen, Lene Seibæk, Marit Eika Jørgensen, Jette Marcussen

There is high prevalence of the genetic SI variant c.273_274delAG in the sucrase-isomaltase-encoding gene in Greenland, resulting in congenital sucrase-isomaltase deficiency and thereby an inability to digest sucrose, the most common dietary sugar. There are no studies of Greenlanders' everyday experiences of sucrose intolerance related to this genetic variant. This study therefore explored, how Greenlandic people experience sucrose intolerance influences life and their attitudes towards research in health and genetics. The study is qualitative, using semi-structured focus groups and/or individual telephone interviews. The analysis was based on the phenomenological-hermeneutic approach of Paul Ricoeur, consisting naïve reading, structural analysis, interpretation and discussion. We identified two themes; "Sucrose intolerance impacts daily living", dealt with physical and emotional reactions and coping with social adaption to activities. And "openness to participate in genetic and health research" were caused by participants wanting more knowledge to improve their people and family's life. The study concluded that most of the participants with symptoms of sucrose intolerance experienced the impact in their daily life, both physically, emotionally, and socially. Further, they expressed openness to participate in health and genetic research. There is a need for more accessible health knowledge and support from health care to manage sucrose intolerance.

在格陵兰岛,蔗糖酶-异麦芽糖酶编码基因中的遗传 SI 变异 c.273_274delAG 的发病率很高,导致先天性蔗糖酶-异麦芽糖酶缺乏症,从而无法消化蔗糖这种最常见的膳食糖。目前还没有关于格陵兰人与这种基因变异有关的蔗糖不耐受的日常经验的研究。因此,本研究探讨格陵兰人如何体验蔗糖不耐受对生活的影响,以及他们对健康和遗传学研究的态度。本研究采用半结构化焦点小组和/或个人电话访谈的定性研究方法。分析以保罗-呂科爾(Paul Ricoeur)的現象學-哲學方法為基礎,包括天真閱讀、結構分析、詮釋和討論。我们确定了两个主题:"蔗糖不耐受对日常生活的影响",涉及身体和情绪反应以及应对社会适应活动。而 "参与遗传和健康研究的开放性 "则是由于参与者希望获得更多知识,以改善自己和家人的生活。研究得出结论,大多数有蔗糖不耐受症状的参与者在日常生活中都感受到了身体、情绪和社交方面的影响。此外,他们还表示愿意参与健康和基因研究。在控制蔗糖不耐受方面,需要更多的健康知识和来自医疗保健的支持。
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引用次数: 0
One health in the Arctic - connections and actions. 北极同一健康--联系与行动。
IF 1.3 4区 医学 Q2 Social Sciences Pub Date : 2024-12-01 Epub Date: 2024-06-13 DOI: 10.1080/22423982.2024.2361544
Jim Berner, Solveig Jore, Khaled Abass, Arja Rautio

There is growing awareness and recognition of the importance of the One Health paradigm to address existing environmental threats and recognise emerging ones at an early stage among Arctic residents, public health agencies, and wildlife resource managers. The One Health approach, emphasising the interconnectedness of human, animal, and ecosystem health, plays a pivotal role in addressing these multifaceted issues. Warming climate and permafrost thaw may influence both contaminant exposure and the spread of zoonotic infectious diseases and have impacts on water and food security. Migration from rural regions to larger communities and urban centres along with increased tourism may be accompanied by changes in exposure to contaminants and zoonotic diseases. Universities have developed educational programmes and research projects on One Health in the Arctic, and under the Arctic Council there is running a project of One Arctic, One Health. These arctivities have produced interdisciplinary information and practical solutions for local communities, decision-makers, and in scientific forums. There is a need for epidemiological zoonotic/human disease models, as well as new approaches to integrate existing and future surveillance data to climatic and environmental data. This requires not only regional and international collaboration but also multi-agency and transdisciplinary research.

北极居民、公共卫生机构和野生动植物资源管理者越来越认识到 "一体健康 "模式对于解决现有环境威胁和早期识别新出现环境威胁的重要性。统一健康 "方法强调人类、动物和生态系统健康之间的相互联系,在解决这些多方面问题方面发挥着关键作用。气候变暖和永久冻土融化可能会影响污染物暴露和人畜共患传染病的传播,并对水和粮食安全产生影响。随着旅游业的发展,人们从农村地区向更大的社区和城市中心迁移,污染物和人畜共患疾病的接触也可能随之发生变化。各大学已经制定了关于北极地区 "同一健康 "的教育计划和研究项目,北极理事会正在实施 "同一北极,同一健康 "项目。这些活动为当地社区、决策者和科学论坛提供了跨学科信息和实用解决方案。需要建立流行病学的人畜共患疾病/人类疾病模型,以及将现有和未来的监测数据与气候和环境数据相结合的新方法。这不仅需要地区和国际合作,还需要多机构和跨学科研究。
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引用次数: 0
Lung cancer in First Nations, Inuit, and Métis peoples in Canada - a scoping review. 加拿大原住民、因纽特人和梅蒂斯人的肺癌--范围界定审查。
IF 1.3 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 Epub Date: 2024-07-29 DOI: 10.1080/22423982.2024.2381879
James Russell O'Grady, Jannatul Ferdus, Sayna Leylachian, Yinka Bolarinwa, Joshua Wagamese, Lisa K Ellison, Connie Siedule, Ricardo Batista, Amanda J Sheppard

Lung cancer is one of the most commonly diagnosed cancers in Canada and a leading cause of cancer mortality. Lung cancer also affects First Nations, Inuit and Métis peoples significantly in Canada, which deserves further investigation as there is a literature gap on this topic. We sought to develop a deeper understanding of lung cancer diagnosis, incidence, mortality, and survival in First Nations, Inuit, and Métis peoples in Canada. A systematic search was conducted in bibliographic databases to identify relevant studies published between January 2000 and March 2023. Articles were screened and assessed for relevance using the Population/ Concept/ Context (PCC) framework. A total of 22 articles were included in the final analysis, of which 13 were Inuit-specific, 7 were First Nations-specific, and 2 were Métis-specific. The literature suggests that comparative incidence, mortality, and relative risk of lung cancer is higher and survival is poorer in First Nations, Inuit and Métis peoples. Lung cancer also has varying impact on these population depending on sex, age, location and other factors. This review illustrates that more comprehensive quantitative and qualitative lung cancer research is essential to further identify the structural causes for the high incidence of the disease.

肺癌是加拿大最常诊断出的癌症之一,也是癌症死亡的主要原因。肺癌对加拿大原住民、因纽特人和梅蒂斯人的影响也很大,由于这方面的文献空白,值得进一步调查。我们试图深入了解加拿大原住民、因纽特人和梅蒂斯人的肺癌诊断、发病率、死亡率和存活率。我们在文献数据库中进行了系统检索,以确定 2000 年 1 月至 2023 年 3 月间发表的相关研究。采用人口/概念/背景 (PCC) 框架对文章进行筛选和相关性评估。共有 22 篇文章被纳入最终分析,其中 13 篇针对因纽特人,7 篇针对原住民,2 篇针对梅蒂斯人。文献表明,原住民、因纽特人和梅蒂斯人的肺癌发病率、死亡率和相对风险相对较高,存活率较低。肺癌对这些人群的影响也因性别、年龄、地区和其他因素而异。本综述表明,必须开展更全面的肺癌定量和定性研究,以进一步确定该疾病高发病率的结构性原因。
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引用次数: 0
Prevalence of indoor air pollutants from First Nation homes in North Central British Columbia, Canada. 加拿大不列颠哥伦比亚省中北部原住民家庭室内空气污染物的普遍性。
IF 1.3 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 Epub Date: 2024-08-22 DOI: 10.1080/22423982.2024.2389612
Ivan Kamurasi, Karen Bartlett, Travis Holyk, Benna Rathburn, Débora Petry Moecke, Ashley Winter, Pat G Camp

Poor indoor air quality poses significant health risks. This study addresses the gap in knowledge regarding the prevalence of indoor air pollutants in remote and rural First Nation communities in north-central British Columbia, Canada. Dust samples from 75 homes were collected and analysed for house dust mites, pet allergens, mould antigens, and bacterial endotoxins. Indoor air quality parameters, including carbon monoxide, carbon dioxide, particulate matter, temperature, and humidity, were measured. A detailed questionnaire on household characteristics and potential pollutant sources was administered. Homes exhibited exposure to multiple pollutants, with wood stove smoke identified as a primary source. Felis domesticus (cat allergen) and Canis familiaris (dog allergen) were prevalent, with detectable levels in 64% and 60% of homes, respectively. Bacterial endotoxins were present in all households. One-third of homes exceeded recommended thresholds for 3 or more pollutants. This study provides critical insights into the prevalence and magnitude of indoor air pollutants, contributing to a broader initiative to characterise respiratory health in First Nations communities. While many homes in First Nations communities had acceptable air quality, one-third of homes exceeded thresholds for 3 or more pollutants. The results can guide ongoing community efforts to address housing concerns and advocate for increased federal funding.

室内空气质量差会对健康造成严重危害。这项研究填补了加拿大不列颠哥伦比亚省中北部偏远农村原住民社区在室内空气污染物流行方面的知识空白。研究人员收集了 75 户家庭的灰尘样本,并对室内尘螨、宠物过敏原、霉菌抗原和细菌内毒素进行了分析。此外,还测量了室内空气质量参数,包括一氧化碳、二氧化碳、颗粒物、温度和湿度。还就家庭特征和潜在污染源进行了详细的问卷调查。结果显示,家庭暴露于多种污染物,其中木柴炉的烟雾是主要来源。猫过敏原和狗过敏原在家庭中普遍存在,分别有 64% 和 60% 的家庭可检测到这两种过敏原。所有家庭都存在细菌内毒素。三分之一的家庭超过了 3 种或更多污染物的建议阈值。这项研究为了解室内空气污染物的普遍性和严重程度提供了重要依据,有助于更广泛地了解原住民社区呼吸系统健康的特点。虽然原住民社区许多家庭的空气质量可以接受,但有三分之一的家庭超过了 3 种或更多污染物的临界值。这些结果可以指导社区解决住房问题的持续努力,并倡导增加联邦资金。
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引用次数: 0
Feasibility of a 12 weeks supervised exercise training intervention among people with Maturity Onset Diabetes of the Young (MODY) or type 2 diabetes in Greenland. 在格陵兰岛的青年期成熟型糖尿病(MODY)或 2 型糖尿病患者中开展为期 12 周的监督运动训练干预的可行性。
IF 1.3 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 Epub Date: 2024-09-20 DOI: 10.1080/22423982.2024.2403794
Laila Motzfeldt, Mathias Ried-Larsen, Freya Jørgensen Hovden, Marit Eika-Jørgensen, Michael Lynge Pedersen, Maja Hykkelbjerg Nielsen

Preventing and managing Type 2 diabetes (T2D) involves adopting healthy lifestyle habits such as balanced nutrition and regular exercise. Maturity Onset Diabetes of The Young (MODY) shares diagnostic characteristics with T2D, but exercise responses in MODY remain unclear. In Greenland, MODY is 4-5 times more common than in other countries. No established exercise regimen exists for either T2D or MODY in Greenland. This study assessed the feasibility of a 12-week supervised exercise programme for MODY and T2D in Greenland, focusing on attendance, satisfaction, and effects on cardiovascular disease (CVD) risk factors and quality of life (QoL). Conducted as an experimental, two-armed, controlled trial, nine participants (4 with MODY) engaged in prescribed training sessions twice weekly for 45-60 minutes, while another nine (4 with MODY) formed the control group. Key outcomes included adherence rates, satisfaction levels, changes in HbA1c, body composition, aerobic fitness, blood pressure, CVD risk factors, and SF-12 scores. Although training adherence was modest at 56%, participant satisfaction remained high. Notable findings included a slight decrease of -0.3 mmol/l in HDL-cholesterol and a 5.7-point increase in the mental component (MCS) of SF-12 within the intervention group. However, the study underscores the need to refine the study design before supervised exercise programmes can be widely implemented in clinical settings in Greenland.

预防和控制 2 型糖尿病(T2D)需要养成健康的生活习惯,如均衡营养和定期锻炼。年轻人成熟期发病糖尿病(MODY)与 T2D 具有相同的诊断特征,但 MODY 的运动反应仍不明确。在格陵兰,MODY 的发病率是其他国家的 4-5 倍。格陵兰没有针对 T2D 或 MODY 的成熟运动疗法。本研究评估了针对格陵兰 MODY 和 T2D 的为期 12 周的监督锻炼计划的可行性,重点关注参加人数、满意度以及对心血管疾病(CVD)风险因素和生活质量(QoL)的影响。作为一项实验性双臂对照试验,九名参与者(其中四名患有中度糖尿病)参加了规定的训练课程,每周两次,每次 45-60 分钟,另外九名参与者(其中四名患有中度糖尿病)组成对照组。主要结果包括坚持率、满意度、HbA1c 变化、身体成分、有氧健身、血压、心血管疾病风险因素和 SF-12 评分。虽然培训坚持率仅为 56%,但参与者的满意度仍然很高。值得注意的发现包括:干预组的高密度脂蛋白胆固醇略微下降了-0.3毫摩尔/升,SF-12的心理成分(MCS)增加了5.7分。不过,这项研究强调,在格陵兰的临床环境中广泛实施监督锻炼计划之前,有必要完善研究设计。
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引用次数: 0
期刊
International Journal of Circumpolar Health
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