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First person – Anaïs Kervadec and James Kezos 第一人称 - 安娜-凯尔瓦达克和詹姆斯-凯佐斯
Pub Date : 2023-07-01 DOI: 10.1242/dmm.050355
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Anaïs Kervadec and James Kezos are co-first authors on ‘ Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm’, published in DMM. Anaïs conducted the research described in this article while a postdoctoral associate in Alexandre Colas' lab at Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA, and is now a scientist at Avidity Biosciences, La Jolla, CA, USA, utilising cutting-edge scientific approaches to discover molecular mechanisms of action, with the ultimate goal of developing novel therapies for patients in need. James is a postdoctoral fellow in the lab of Karen Ocorr at Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA, utilising multimodel system approaches to investigate genetic, molecular and physiological mechanisms underlying cardiac development and disease.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Anaïs Kervadec和James Kezos是发表在《DMM》上的《心房颤动的多平台建模识别出磷酸蛋白是心律的中枢调节剂》的共同第一作者。Anaïs在美国加利福尼亚州拉霍亚市Sanford Burnham Prebys医学发现研究所的Alexandre Colas实验室担任博士后时进行了本文中描述的研究,现在是美国加利福尼亚州拉霍亚市Avidity Biosciences的科学家,利用尖端的科学方法发现分子作用机制,最终目标是为有需要的患者开发新的治疗方法。James是Sanford Burnham Prebys医学发现研究所(La Jolla, CA, USA) Karen Ocorr实验室的博士后研究员,利用多模型系统方法研究心脏发育和疾病的遗传、分子和生理机制。
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引用次数: 0
First person – Kevin Zhang 第一人称——张凯文
Pub Date : 2023-07-01 DOI: 10.1242/dmm.050389
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Kevin Zhang is first author on ‘ Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells’, published in DMM. Kevin is an MD/PhD student in the lab of Dr Joshua Dunaief at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA, investigating the cell biology and metabolism of the eye.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。张凯文是《氧化应激诱导溶酶体膜渗透和视网膜色素上皮细胞神经酰胺积累》的第一作者,发表于《DMM》杂志。Kevin是美国宾夕法尼亚大学佩雷尔曼医学院Joshua Dunaief博士实验室的一名医学博士/博士生,研究眼睛的细胞生物学和代谢。
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引用次数: 0
Unsheathing new insights into lysosomal storage disorders 揭示溶酶体贮积障碍的新见解
Pub Date : 2023-06-27 DOI: 10.1242/dmm.050364
Kirsty M Hooper
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引用次数: 0
First person – Valentina Zuco 第一人称,瓦伦蒂娜·祖科
Pub Date : 2023-06-01 DOI: 10.1242/dmm.050313
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Valentina Zuco is first author on ‘ Effects of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograft’, published in DMM. Valentina is a scientist in the lab of Nadia Zaffaroni at Fondazione IRCCS Istituto Tumori, Milan, Italy, investigating patient-derived tumor models to identify new therapeutic strategies for patients with rare cancers to be translated into clinical trials.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Valentina Zuco是发表在《DMM》上的《伊立替康加trabectedin对促结扎小圆细胞肿瘤患者来源的异种移植物的影响》的第一作者。Valentina是意大利米兰基金会IRCCS肿瘤研究所Nadia Zaffaroni实验室的一名科学家,她正在研究患者衍生的肿瘤模型,以确定针对罕见癌症患者的新治疗策略,并将其转化为临床试验。
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引用次数: 0
First person – Sara Bonzano 第一人称- Sara Bonzano
Pub Date : 2023-06-01 DOI: 10.1242/dmm.050335
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Sara Bonzano is first author on ‘ NR2F1 shapes mitochondria in the mouse brain, providing new insights into Bosch-Boonstra-Schaaf optic atrophy syndrome’, published in DMM. Sara is a postdoc in the lab of Silvia De Marchis at the University of Turin, Turin, Italy, investigating the cellular and molecular mechanisms by which NR2F1 regulates postnatal brain plasticity.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Sara Bonzano是“NR2F1塑造小鼠大脑中的线粒体,为Bosch-Boonstra-Schaaf视神经萎缩综合征提供了新的见解”的第一作者,发表在DMM上。Sara是意大利都灵大学Silvia De Marchis实验室的博士后,研究NR2F1调节出生后大脑可塑性的细胞和分子机制。
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引用次数: 0
Getting to the cortex of sexual dimorphism 进入两性异形的大脑皮层
Pub Date : 2023-06-01 DOI: 10.1242/dmm.050370
Kirsty M Hooper
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引用次数: 0
First person – Lorena Maili
Pub Date : 2023-06-01 DOI: 10.1242/dmm.050302
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Lorena Maili is first author on ‘ Facial analytics based on a coordinate extrapolation system (zFACE) for morphometric phenotyping of developing zebrafish’, published in DMM. Lorena conduced the research described in the article while a graduate research assistant (predoctoral student) in the lab of Dr Jacqueline Hecht (in collaboration with Dr George Eisenhoffer) at The University of Texas MD Anderson Cancer Center, Houston, TX, USA. She is now a postdoctoral fellow in the lab of Dr Paul Trainor at Stowers Institute for Medical Research, Kansas City, MO, USA, investigating genetic regulation of craniofacial development.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Lorena Maili是“基于坐标外推系统(zFACE)的发育中斑马鱼形态表型面部分析”的第一作者,发表于DMM。Lorena在美国德克萨斯州休斯顿的德克萨斯大学MD安德森癌症中心担任杰奎琳·赫克特博士(与乔治·艾森霍夫博士合作)实验室的研究生助理(博士生前)时进行了文章中描述的研究。她现在是美国密苏里州堪萨斯城Stowers医学研究所Paul Trainor博士实验室的博士后,研究颅面发育的遗传调控。
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引用次数: 0
First person – Rodanthi Lyraki 第一人称- Rodanthi Lyraki
Pub Date : 2023-05-10 DOI: 10.1242/dmm.050246
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Rodanthi Lyraki is first author on ‘ Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice’, published in DMM. Rodanthi conducted the research described in this article while a postdoctoral Fellow in Andreas Schedl's lab at Université Côte d’Azur, Nice, France.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Rodanthi Lyraki是“雄激素受体与WNT/β-连环蛋白信号之间的串扰导致小鼠性别特异性肾上腺皮质增生”的第一作者,发表于《DMM》杂志。Rodanthi在法国尼斯大学(universit Côte d’azur)的Andreas Schedl实验室做博士后时进行了本文中描述的研究。
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引用次数: 0
First person – Arthur Lensen and Margarida C. Gomes 第一人称:阿瑟·伦森和玛格丽达·c·戈麦斯
Pub Date : 2023-05-10 DOI: 10.1242/dmm.050255
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Arthur Lensen and Margarida C. Gomes are co-first authors on ‘ An automated microscopy workflow to study Shigella–neutrophil interactions and antibiotic efficacy in vivo’, published in DMM. Arthur conducted the research described in this article while an MSc student in Serge Mostowy's lab at the London School of Hygiene and Tropical Medicine, UK. He is now a PhD student in the lab of Jost Enninga at Institut Pasteur, Paris, France, investigating host-pathogen interactions at the cellular and molecular level. Margarida is a research fellow in Serge Mostowy's lab at the London School of Hygiene and Tropical Medicine, UK, and works with the zebrafish infection model to study host-pathogen interactions, focusing on trained innate immunity.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Arthur Lensen和Margarida C. Gomes是《研究志贺氏菌-中性粒细胞相互作用和体内抗生素疗效的自动化显微镜工作流程》的共同第一作者,发表在《DMM》杂志上。Arthur在英国伦敦卫生和热带医学学院Serge Mostowy的实验室攻读硕士学位时进行了本文中描述的研究。他现在是法国巴黎巴斯德研究所Jost Enninga实验室的博士生,在细胞和分子水平上研究宿主-病原体的相互作用。Margarida是英国伦敦卫生和热带医学学院Serge Mostowy实验室的一名研究员,她利用斑马鱼感染模型研究宿主-病原体相互作用,重点研究训练后的先天免疫。
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引用次数: 0
First person – Ariany Oliveira-Santos
Pub Date : 2023-05-10 DOI: 10.1242/dmm.050221
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Ariany Oliveira-Santos is first author on ‘ Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy’, published in DMM. Ariany is a postdoctoral researcher in the lab of Dean Burkin at the University of Nevada, Reno, USA, investigating muscle biology and the development of new therapeutics for muscle diseases, particularly muscular dystrophies.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Ariany Oliveira-Santos是“Vemurafenib改善lama2相关先天性肌营养不良小鼠模型的肌肉组织病理学”的第一作者,发表在DMM上。Ariany是美国内华达大学里诺分校Dean Burkin实验室的博士后研究员,研究肌肉生物学和肌肉疾病,特别是肌肉萎缩症的新疗法的发展。
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引用次数: 0
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Disease Models & Mechanisms
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