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Disease Models & Mechanisms最新文献

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First person – Zongwang Zhang 第一人——张宗旺
Pub Date : 2022-12-07 DOI: 10.1242/dmm.050003
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Zongwang Zhang is first author on ‘ A DUSP6 inhibitor suppresses inflammatory cardiac remodeling and improves heart function after myocardial infarction’, published in DMM. Zongwang is a PhD student in the lab of Jing-Wei Xiong at Peking University, Beijing, China, investigating therapeutic targets and drugs for cardiovascular diseases.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。张宗旺,第一作者《A DUSP6 inhibitor抑制炎症性心脏重构,改善心肌梗死后心功能》发表于《DMM》杂志。王宗旺是北京大学熊景伟实验室的博士生,研究心血管疾病的治疗靶点和药物。
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引用次数: 0
Pulling back the curtain: live imaging adult disease processes 拉开帷幕:成人疾病过程的实时成像
Pub Date : 2022-12-01 DOI: 10.1242/dmm.050027
K. Kwan
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引用次数: 0
First person – Arnaud Duchon 第一人称,阿尔诺·杜雄
Pub Date : 2022-12-01 DOI: 10.1242/dmm.049964
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Arnaud Duchon is first author on ‘ Ts66Yah, a mouse model of Down syndrome with improved construct and face validity’, published in DMM. Arnaud is a PhD research engineer in the lab of Yann Herault at the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch-Graffenstaden, France, investigating trisomy 21 (Down syndrome) with mouse model approaches.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Arnaud Duchon是发表在DMM上的“Ts66Yah,一种具有改进结构和面部效度的唐氏综合症小鼠模型”的第一作者。Arnaud是法国伊尔基希-格拉芬斯塔登(Illkirch-Graffenstaden)的gsamn Herault研究所(IGBMC)实验室的博士研究工程师,他正在用小鼠模型方法研究21三体(唐氏综合症)。
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引用次数: 0
First person – Emily Warren 第一人称,艾米丽·沃伦
Pub Date : 2022-12-01 DOI: 10.1242/dmm.050017
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Emily Warren is first author on ‘ 17q12 deletion syndrome mouse model shows defects in craniofacial, brain and kidney development, and glucose homeostasis’, published in DMM. Emily conducted the research described in this article while a postdoctoral fellow in Eric M. Morrow's lab at Brown University, Providence, RI, USA. She is now a postdoctoral fellow in the lab of Peter J. McGuire at the National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI), Bethesda, MD, USA, investigating how metabolic dysfunction impacts the brain, particularly in the context of neurodevelopment and neurodegeneration.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Emily Warren是《17q12缺失综合征小鼠模型显示颅面、大脑和肾脏发育缺陷以及葡萄糖稳态》的第一作者,发表于《DMM》杂志。艾米丽在美国普罗维登斯布朗大学埃里克·m·莫罗实验室做博士后时进行了本文中描述的研究。她现在是美国国立卫生研究院(NIH)国家人类基因组研究所(NHGRI) Peter J. McGuire实验室的博士后,研究代谢功能障碍如何影响大脑,特别是在神经发育和神经变性的背景下。
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引用次数: 0
COVID-19's next top model 2019冠状病毒病的下一位超模
Pub Date : 2022-11-01 DOI: 10.1242/dmm.049972
Kirsty M Hooper
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引用次数: 0
First person – Xiao Li 第一人称 - Xiao Li
Pub Date : 2022-11-01 DOI: 10.1242/dmm.049968
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Xiao Li is first author on ‘ Cdk8 attenuates lipogenesis by inhibiting SREBP-dependent transcription in Drosophila’, published in DMM. Xiao conducted the research described in this article while a graduate student in Jun-yuan Ji's lab at Texas A&M University Health Science Center, College Station, TX, USA. He is now a postdoctoral fellow in the lab of Michael Levine at Princeton University, Princeton, NJ, USA, investigating the mechanisms of transcription regulation.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。李晓是《Cdk8通过抑制果蝇srebp依赖性转录来减缓脂肪生成》的第一作者,发表于《DMM》杂志。肖在美国德克萨斯州大学城的德州农工大学健康科学中心的季军元实验室进行了本文中描述的研究,当时他还是一名研究生。现为美国普林斯顿大学Michael Levine实验室博士后,研究转录调控机制。
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引用次数: 0
First person – Payel Kundu 第一人称——Payel Kundu
Pub Date : 2022-11-01 DOI: 10.1242/dmm.049983
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Payel Kundu is first author on ‘ Xanthohumol improves cognition in farnesoid X receptor-deficient mice on a high-fat diet’, published in DMM. Payel conducted the research described in this article while a postdoctoral fellow in Jacob Raber's lab at Oregon Health and Science University, Portland, OR, USA. She is now a health scientist in the lab of Sharlee More at Cardno ChemRisk, Aliso Viejo, CA, USA, intervening on metabolism to promote healthy cognitive ageing and reduce the detrimental effects of consumption of a Western diet.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Payel Kundu是发表在《DMM》杂志上的《黄腐酚改善高脂肪饮食中法甾体X受体缺陷小鼠的认知能力》一文的第一作者。Payel在美国俄勒冈州波特兰市俄勒冈健康与科学大学Jacob Raber实验室做博士后时进行了本文中描述的研究。她现在是美国加州Aliso Viejo的Cardno ChemRisk的Sharlee More实验室的健康科学家,通过干预新陈代谢来促进健康的认知老化,减少西方饮食的有害影响。
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引用次数: 0
Reducing the shock factor with new anti-epilepsy drugs 新型抗癫痫药物降低休克因子
Pub Date : 2022-10-01 DOI: 10.1242/dmm.049886
K. Hooper
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引用次数: 0
First person – Sai Sanwid Pradhan 第一人称,Sai Sanwid Pradhan
Pub Date : 2022-10-01 DOI: 10.1242/dmm.049895
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Sai Pradhan is first author on ‘ Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation’, published in DMM. Sai Sanwid is a PhD Student in the lab of Venketesh Sivaramakrishnan at the Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, India, investigating neurodegenerative diseases, like Huntington disease, which are caused by protein aggregation. His research interest is focused on understanding the mechanisms associated with disease progression and identifying potential biomarkers associated with progression and prognosis, as well as therapeutic targets and agents that confer neuroprotection for better management of the disease.
《第一人称》是对发表在《疾病模型与机制》上的论文的第一作者的一系列采访,帮助研究人员在论文的同时提升自己。Sai Pradhan是发表在《DMM》杂志上的《亨廷顿病的综合多组学分析确定调节蛋白质聚集的途径》的第一作者。Sai Sanwid是印度Anantapur Prasanthi Nilayam的Sri Sathya Sai高等教育学院Venketesh Sivaramakrishnan实验室的一名博士生,研究由蛋白质聚集引起的神经退行性疾病,如亨廷顿病。他的研究兴趣集中在了解与疾病进展相关的机制,识别与进展和预后相关的潜在生物标志物,以及赋予神经保护的治疗靶点和药物,以更好地管理疾病。
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引用次数: 0
Genetic tricks to track melanoma heterogeneity 追踪黑色素瘤异质性的基因技巧
Pub Date : 2022-09-01 DOI: 10.1242/dmm.049875
C. Mosimann
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引用次数: 0
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Disease Models & Mechanisms
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