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Relationship between the Goslon Yardstick and Lateral Cephalometric Analysis Values after Palatoplasty in Unilateral Cleft Lip and Palate Patients 单侧唇腭裂患者腭成形术后高斯隆尺度与侧位测量分析值的关系
Pub Date : 2021-10-20 DOI: 10.5466/ijoms.20.132
Takenobu Ishii, Jyuri Miyajima, Taiki Morikawa, T. Sakamoto, Y. Nishii
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引用次数: 0
Application of a Deep Learning Artificial Intelligence System for Individual Tooth Identification 深度学习人工智能系统在个体牙齿识别中的应用
Pub Date : 2021-10-20 DOI: 10.5466/ijoms.20.98
Y. Igarashi, S. Kondo, M. Kaneko, Megumi Aibara, F. Uchikoba
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引用次数: 1
Using Smartphone Technology to Impart Basic Pediatric Dentistry Knowledge to Early Childhood Educators: a Preliminary Study 利用智能手机技术向幼儿教育者传授儿童牙科基础知识的初步研究
Pub Date : 2021-10-20 DOI: 10.5466/ijoms.20.152
Y. Myoken, T. Kawamoto, Masako Nakata, S. Toratani, Y. Fujita, Y. Myoken
This study aimed to evaluate the use of web-based educational slides providing an-ticipatory guidance on infant oral health and early-childhood caries(ECC)to early-child-hood educators. Slides containing basic guidance in the areas of oral hygiene, fluoride use, the acquisition of oral bacteria, the causes and sequelae of ECC, and the importance of dental visits were provided using smartphones. A test based on six key questions was conducted to evaluate the oral health knowledge of the educators(n=123)be-fore and after viewing the slides. A survey was used to receive participants’ feedback after viewing the slides. A significant improvement in knowledge was observed as assessed by the mean proportion of correct responses following a single viewing of the slides(47±17.8%, p<0.001). More than 85% of the participants answered positively on the survey about the slides. Web-based educational slides on smartphones can be an effective way to improve educators’ awareness of infant oral health and prevention of ECC.
本研究旨在评估基于网络的教育幻灯片为幼儿教育工作者提供婴儿口腔健康和幼儿龋齿(ECC)参与式指导的使用情况。通过智能手机提供了包含口腔卫生、氟化物使用、口腔细菌获取、ECC的原因和后遗症以及牙科就诊重要性等领域基本指导的幻灯片。通过六个关键问题的测试来评估教育工作者(n=123)在观看幻灯片之前和之后的口腔健康知识。一项调查用于接收参与者在观看幻灯片后的反馈。通过单次观看幻灯片后正确回答的平均比例(47±17.8%,p<0.001),可以观察到知识的显著提高。超过85%的参与者在调查中对幻灯片做出了肯定的回答。基于网络的智能手机教育幻灯片是提高教育工作者对婴幼儿口腔健康和预防ECC的意识的有效途径。
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引用次数: 0
Interaction between Interleukin-1α and Protease-activated Receptor-2 in Human Buccal Mucosa Epithelial Cells 人口腔黏膜上皮细胞白细胞介素-1α与蛋白酶活化受体-2的相互作用
Pub Date : 2021-10-20 DOI: 10.5466/ijoms.20.144
H. Matsumoto, H. Nishimura, M. Komiya
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引用次数: 0
Mechanism of Drug-induced Gingival Overgrowth: Phenytoin Inhibits the Apoptosis of Human Gingival Fibroblasts 药物诱导牙龈过度生长的机制:苯妥英抑制人牙龈成纤维细胞凋亡
Pub Date : 2021-10-20 DOI: 10.5466/ijoms.20.109
R. Takeuchi, H. Matsumoto, C. Taguchi, Yuichiro Okada, Masaru Mizuta, T. Yamada, T. Aso, Haruka Sakazume, K. Arikawa, K. Hiratsuka
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引用次数: 1
Sex-dependency of the Examination of Near-infrared Spectroscopy in Patient with Halitosis 口臭患者近红外光谱检查的性别依赖性
Pub Date : 2021-10-20 DOI: 10.5466/ijoms.20.117
M. Ohta, A. Yoshino, Ryouhei Iwahashi, Suguru Momohara, M. Kajimoto, Shinichiro Aoki, Yasuhiro Okamoto, T. Uchida, H. Endo, S. Osawa
anatomical difference between the brains of both sexes has been reported; specifically, that the cortex is thicker in women than in men(9). This is considered to be one of the factors affecting the NIRS dataset. Women are also known to be more prone to depression than men(10, 11). The tendency to become depressed seems to be related to attention, concentration, judgment, and reduced memory, and there may also sex-related differences in human cognitive function. Thus, it was hypothesized that sex differences also appear in Abstract The data on near-infrared spectroscopy(NIRS)corresponding to the left dorsolateral prefrontal cortex can be used as diagnostic criterion for psychological halitosis. Howev-er, it is unclear how sex differences affect them. Thus, this study aimed to investigate the influence of the differences between sexes using NIRS to diagnose psychological halitosis. The study included 42 patients(21 men and 21 women)with presumed psychological halitosis. All patients underwent volatile sulfur compounds(VSC)concentration analysis and psychological testing. They were investigated using NIRS during the performance of the verbal fluency task. Although 16 channels were measured in total, and the channels 13, 14, and 16 that corresponded to the left dorsolateral prefrontal cortex were analyzed. The results demonstrated that no significant differences were observed between VSC and psychological tests. The integral values and initial activation on the NIRS were significantly higher in men; thus, sex differences were observed. In conclu-sion, the present study suggests that sex differences should be considered when using NIRS as a diagnostic tool for patients with psychological halitosis.
两性大脑的解剖学差异已被报道;具体来说,女性的大脑皮层比男性厚(9)。这被认为是影响近红外光谱数据集的因素之一。女性也比男性更容易患抑郁症(10,11)。抑郁的倾向似乎与注意力、注意力、判断力和记忆力下降有关,而且人类认知功能也可能存在与性别有关的差异。左侧背外侧前额叶皮层对应的近红外光谱(NIRS)数据可作为心理口臭的诊断标准。然而,目前还不清楚性别差异如何影响他们。因此,本研究旨在探讨性别差异对近红外光谱诊断心理口臭的影响。该研究包括42例(21名男性和21名女性)推定为心理口臭的患者。所有患者均进行挥发性硫化合物(VSC)浓度分析和心理测试。他们在执行语言流畅性任务时使用近红外光谱进行了调查。虽然共测量了16个通道,并分析了对应于左背外侧前额皮质的13、14和16通道。结果表明,VSC与心理测试之间无显著差异。男性NIRS积分值和初始激活值显著高于男性;因此,性别差异被观察到。综上所述,本研究提示在使用近红外光谱作为心理口臭患者的诊断工具时应考虑性别差异。
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引用次数: 0
The Effect of Porphyromonas gingivalis Augmented Invasion by TNF-α on Gingival Fibroblasts Derived from Down Syndrome TNF-α增强牙龈卟啉单胞菌侵袭唐氏综合征牙龈成纤维细胞的作用
Pub Date : 2021-10-20 DOI: 10.5466/ijoms.20.87
Kazukuni Ichikawa, Manabu Yaguchi, Yoko Tanaka
It is well known the high prevalence periodontal disease in Down syndrome(DS). Tumor necrosis factor alpha(TNF-α)augments invasion of Porphyromonas gingivalis(P. gingivalis)in human gingival epithelial cells. We examined the effect of TNF-α on invasion of P. gingivalis to gingival fibroblasts derived from individuals with DS(DGF)and the influence of the cellular response in DGF pretreated with TNF-α prior to inoculation of P. gingivalis. The invasion assay was performed using gingival fibroblasts derived from individuals with non-DS(NGF)and DGF treated with TNF-α prior to inoculation of P. gingivalis. The mRNA expression of interleukin 6(IL-6)and intercellular adhesion molecule 1(ICAM-1)were quantified using real time PCR. Furthermore, the protein expressions of TNF-α receptor(TNFR)I and II, and phosphorylation of p65 nu-clear factor-κB(NF-κB)and phosphorylation of extracellular signal-regulated kinase (ERK)1/2 were also performed in NGF and DGF pretreated with TNF-α prior to inoculation of P. gingivalis by Western blotting. The number of invasive P. gingivalis in TNF-α pretreated DGF was more than that in NGF. IL-6 and ICAM-1 mRNA expressions in DGF pretreated with TNF-α prior to inoculation of P. gingivalis were significantly higher than those in NGF. The relative signal intensity of TNFR I, phospho p-65 NF-κB, and phospho ERK1/2 were significantly higher than those in NGF. It was considered that TNFR I, phospho p65 NF-κB, and phospho ERK1/2 in DGF pretreated with TNF-α may contribute to enhancement of ICMA-1 mRNA expression and the infection of P. gingivalis. The collaboration of these protein and P. gingivalis may be a key factor for development of severe periodontal disease in DS. anaerobic conditions for 7 days. The colonies were count-ed to determine the number of colony - forming units (CFUs)of invasive P. gingivalis in fibroblast cells. Inva sion assays were performed 3 times for each sample.
众所周知,唐氏综合征(DS)的牙周病患病率很高。肿瘤坏死因子α (TNF-α)增加了牙龈卟啉单胞菌的侵袭。人牙龈上皮细胞中的牙龈病。我们检测了TNF-α对DS(DGF)患者牙龈成纤维细胞侵袭的影响,以及接种牙龈卟啉卟啉前TNF-α预处理DGF的细胞反应的影响。侵袭实验采用非ds (NGF)和DGF个体的牙龈成纤维细胞,在接种牙龈假单胞菌之前用TNF-α处理。实时荧光定量PCR法检测白细胞介素6(IL-6)和细胞间粘附分子1(ICAM-1) mRNA表达量。免疫印迹法检测接种前TNF-α预处理的NGF和DGF中TNF-α受体(TNFR)I和II蛋白表达、p65核清晰因子-κB(NF-κB)磷酸化和细胞外信号调节激酶(ERK)1/2磷酸化。TNF-α预处理的DGF组侵袭性牙龈假单胞菌数量多于NGF组。接种牙龈假单胞菌前用TNF-α预处理的DGF中IL-6和ICAM-1 mRNA的表达量显著高于NGF。tnf - I、磷酸化p-65 NF-κB和磷酸化ERK1/2的相对信号强度显著高于NGF。我们认为TNF-α预处理的DGF中TNF- I、phospho p65 NF-κB和phospho ERK1/2可能参与了ICMA-1 mRNA表达的增强和牙龈P.感染的发生。这些蛋白与牙龈卟啉卟啉菌的协同作用可能是退行性痴呆患者发生严重牙周病的关键因素。厌氧条件7天。计数菌落,测定侵袭性牙龈假单胞菌在成纤维细胞中的菌落形成单位(colony - forming units, cfu)数量。每个样品进行3次侵袭试验。
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引用次数: 0
Quantitative Assessment of the Age-related Change of Inferior Alveolar Neurovascular Bundle Using Diffusion Weighted Magnetic Resonance Imaging 磁共振弥散加权成像定量评价下肺泡神经血管束年龄相关性变化
Pub Date : 2021-06-30 DOI: 10.5466/ijoms.20.31
H. Muraoka, Naohisa Hirahara, Ko Ito, S. Tokunaga, Shunya Okada, Kohei Otsuka, T. Komatsu, Takumi Kondo, T. Kaneda
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引用次数: 0
Bad Split in Bilateral Sagittal Split Ramus Osteotomy: A Retrospective Study of 745 Patients for Evading Bad Split 双侧矢状劈裂支截骨术中的严重劈裂:745例回避严重劈裂患者的回顾性研究
Pub Date : 2021-06-30 DOI: 10.5466/ijoms.20.50
Kiyohiro Kasahara, K. Sugahara, Masahide Koyachi, A. Nishiyama, M. Yamamoto, Masashi Iwamoto, Akira Watanabe, M. Takano, A. Katakura
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引用次数: 0
Effect of Alkaline–hydrolyzed Bioactive Poly(Lactic Acid-ε-caprolactone)Film on Apatite Precipitation in Simulated Body Fluid 碱性水解生物活性聚乳酸-ε-己内酯膜对模拟体液中磷灰石沉淀的影响
Pub Date : 2021-06-30 DOI: 10.5466/ijoms.20.11
M. Fuse, T. Takizawa, C. Taguchi, K. Nakajima, Takao Kuwada Kusunose
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International Journal of Oral-Medical Sciences
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