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The Impact of Electronic Prescribing System Factors on Prescribing Decision Making: A Systematic Review and Narrative Synthesis 电子处方系统因素对处方决策的影响:系统回顾与叙述综述
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.003
N. Alaboud, Y. Jani, B. D. Franklin
Medication prescribing is a complex and error-prone process in clinical practice1. Using electronic prescribing systems (EP) allow healthcare providers to prescribe medications electronically. However, many factors can affect the implementation and utilisation of EP systems, including factors related to the end-users, system, and organization2. This systematic review aimed to explore and synthesise the literature on the impact of EP system factors on prescribing decision-making. Objectives were to: map the current evidence for EP system factors that inhibit or facilitate prescribing decision-making; identify the positive and negative impact of different design features or data integration of EP systems on prescribing decision-making; identify evidence on the most effective ways to display patient-specific data to aid prescribers in making their prescribing decisions; and make recommendations for future clinical practice and research in designing EP systems. We searched PubMed, Medline, Embase and the Cumulative Index to Nursing Allied Health Literature databases for studies published from January 2000 to February 2023 We included all types of primary studies (both evaluative and descriptive study designs) that explored the effect of EP system factors on prescribing decision-making in any healthcare setting. Methodological quality was assessed using the Mixed Methods Appraisal Tool (MMAT)3. Emergent themes were identified and subjected to narrative synthesis. The protocol was registered with PROSPERO (registration: CRD42021235988). Searches identified 6752; after deduplication, 4925 articles underwent title and abstract screening, and 227 underwent full-text review, of which 54 were included from 13 different countries. There were a range of study designs; most (n=30) adopted quantitative methods such as retrospective evaluation by extracting the data from an EP system, nine adopted qualitative approaches such as interviews, and a further 15 used mixed methods. According to MMAT, 32 of 54 studies were deemed to be of high quality. Based on the findings of included studies, three key EP system factors were derived that could affect medication-related decision-making during prescribing processes: (1) design features of CDSS within EP system (how the EP system design interact with the prescriber at the point of prescribing and which design feature has been used), (2) displayed information at the point of prescribing (what and how data displayed to the prescriber at point of prescribing) and (3) Type of EP system based on the system developer (a commercial vs. a homegrown EP system). A total of 18 EP system factors were found that have either positive or negative effects on influencing prescribers’ decision-making and prescribing workflow. The end-users of the EP system played essential roles in system acceptance, and its success in real practices. However, there is a need for more consensus within the literature on designi
在临床实践中,药物处方是一个复杂且容易出错的过程1。使用电子处方系统(EP)可让医疗服务提供者以电子方式开具处方。然而,许多因素会影响电子处方系统的实施和使用,包括与最终用户、系统和组织相关的因素2。 本系统综述旨在探讨和综合有关 EP 系统因素对处方决策影响的文献。目的是:梳理目前有关电子病历系统抑制或促进处方决策的因素的证据;确定电子病历系统的不同设计特点或数据整合对处方决策的积极和消极影响;确定有关显示患者特定数据的最有效方法的证据,以帮助处方者做出处方决策;并对未来的临床实践和电子病历系统设计研究提出建议。 我们检索了 PubMed、Medline、Embase 和 Cumulative Index to Nursing Allied Health Literature 数据库中 2000 年 1 月至 2023 年 2 月期间发表的研究。我们纳入了探讨 EP 系统因素对任何医疗机构处方决策影响的所有类型的主要研究(包括评价性和描述性研究设计)。我们使用混合方法评估工具(MMAT)3 对方法学质量进行了评估,确定了新出现的主题,并对其进行了叙事综合。研究方案已在 PROSPERO 注册(注册号:CRD42021235988)。 搜索共发现了 6752 篇文章;经过重复筛选后,有 4925 篇文章通过了标题和摘要筛选,227 篇文章通过了全文审阅,其中 54 篇文章来自 13 个不同的国家。研究设计多种多样;大多数(n=30)采用了定量方法,如通过从 EP 系统中提取数据进行回顾性评估,9 篇采用了定性方法,如访谈,另有 15 篇采用了混合方法。根据 MMAT,54 项研究中有 32 项被认为是高质量的。根据纳入研究的结果,得出了可能影响处方过程中药物相关决策的三个关键 EP 系统因素:(1)EP 系统中 CDSS 的设计特征(EP 系统的设计如何在处方时与处方者互动,以及使用了哪些设计特征);(2)处方时显示的信息(处方时向处方者显示哪些数据以及如何显示数据);(3)基于系统开发者的 EP 系统类型(商业 EP 系统与自制 EP 系统)。 共发现 18 个 EP 系统因素对处方者的决策和处方工作流程有积极或消极的影响。EP 系统的最终用户对系统的接受度及其在实际工作中的成功发挥了至关重要的作用。然而,在设计、实施和评估 EP 系统的文献中,还需要就如何以及何时评估系统内的任何新修改达成更多共识。未来的研究应探索对处方决策产生积极影响的不同设计策略,并从那些不成功的设计策略中吸取经验教训,以制定 EP 系统设计指南/标准。 1.Samadbeik, M., M. Ahmadi, and S.M. Hosseini Asanjan, A theoretical approach to electronic prescription system: lesson learned from literature review.Iran Red Crescent Med J, 2013.15(10): p. e8436. 2.Sweidan, M., et al., Identification of features of electronic prescribing systems to support quality and safety in primary care using a modified Delphi process.BMC Med Inform Decis Mak, 2010.10: p. 21. 3.Hong, Q.N., et al., The Mixed Methods Appraisal Tool (MMAT) version 2018 for information professionals and researchers.信息教育,2018.34(4): p. 285-291.
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引用次数: 0
Evaluation of the impact of a Pharmacy Technician within the Emergency Department, Royal Stoke University Hospital 评估皇家斯托克大学医院急诊科药房技术员的影响
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.030
B. A. Jacklin, V. J. Marson, N. Bailey, F. Bevan
The Emergency Department (ED) at the Royal Stoke University Hospital has come under increasing pressure, and it is well published that patients within the ED are at a higher risk of medication misadventure and missed doses of critical medicines1. This was a particular risk at the Royal Stoke in winter 2022/23 with the re-introduction of ED corridor care and patients waiting over 24 hours for a medical bed. A prescribing pharmacist has been in post in the ED since 2019, but additional funding was obtained for a pharmacy ED technician to support for 6 months during winter pressures. The aim of this service evaluation was to assess the impact of the pharmacy technician within the ED, with a particular focus on medicines reconciliation, allergy status recognition and pharmacist prescribing activity. Ethical approval was not required for this project, as it was a service evaluation. Data was collected over an 11 week period, Monday-Friday from October-December 2022. Data was collated into an Excel® spread sheet and assessed the number of patients reviewed by the pharmacy technician and prescribing pharmacist, the number of medicines prescribed by a prescribing pharmacist (including number of critical and non-critical medicines), and any missed allergy status’ by the clerking practitioner. Over 11 weeks, the pharmacist prescriber was able to prescribe 183 medicines, 46 of which were critical medicines. 23 patients were identified as having allergies (with 61% being penicillin allergy) which had previously not been documented by the clerking practitioner within the ED and/or patients were not wearing the appropriate red allergy wristband. This included 2 patients who had previously experienced anaphylaxis as a result of their drug allergy. Finally, comparing the data from the time period with the pharmacy technician, to without a pharmacy technician, demonstrated an almost 10-fold increase in pharmacist prescribing activity. This service evaluation has demonstrated the significant positive impact of a pharmacy technician within the ED. The data collected for this service evaluation was limited as it was only collected on weekdays, and further work should be done to assess the impact of a 7 day service. It is therefore recommended that permanent funding is secured all year round for ED pharmacy technician support, ideally 7 days per week. This will increase medicines reconciliation activity allowing ED pharmacists to focus on clinical review and prescribing for patients, increasing the number of patients seen by pharmacy, allowing earlier identification of patients on critical medicines, reducing the number of missed doses and potential harm. A pharmacy technician also allows earlier confirmation of patients’ allergy status, further reducing harm within the ED. 1. NICE Guideline (NG5). Medicines Optimisation: the safe and effective use of medicines to enable the best possible outcomes. Published 4th March 2015.
英国皇家斯托克大学医院急诊科(ED)面临的压力越来越大,有资料显示,急诊科病人用药不当和错过关键药物剂量的风险较高1。2022/23 年冬季,随着急诊室走廊护理的重新实施,病人等待医疗床位的时间超过了 24 小时,这种风险在斯托克皇家大学医院尤为突出。自 2019 年以来,急诊室一直有一名开处方的药剂师在岗,但在冬季压力期间,急诊室还获得了额外资金,用于聘用一名急诊室药剂技师,为期 6 个月。 这项服务评估的目的是评估药剂师在急诊室的影响,尤其是在药品协调、过敏状态识别和药剂师处方活动方面。 由于这是一项服务评估,因此无需获得伦理批准。数据收集时间为 2022 年 10 月至 12 月的周一至周五,为期 11 周。数据被整理到 Excel® 电子表格中,并评估了由药剂师和处方药剂师审核的患者人数、处方药剂师开具的药品数量(包括关键和非关键药品的数量),以及文秘从业人员遗漏的 "过敏状态"。 在 11 周的时间里,药剂师能够开出 183 种药品,其中 46 种是关键药品。23 名患者被确定为过敏体质(61% 为青霉素过敏),而这些过敏体质之前并未被急诊室的文员记录在案,并且/或者患者未佩戴适当的红色过敏腕带。这其中包括两名曾因药物过敏而导致过敏性休克的患者。最后,对比有药剂师和没有药剂师期间的数据,发现药剂师的处方活动几乎增加了 10 倍。 这项服务评估表明,在急诊室配备药剂技师会产生重大的积极影响。这项服务评估收集的数据有限,因为只收集了工作日的数据,因此应进一步开展工作,评估 7 天服务的影响。因此,建议全年为急诊室药剂技师支持提供长期资助,最好每周 7 天。这将增加药品核对活动,使急诊室药剂师能够集中精力为患者进行临床审查和开处方,增加药剂师接诊的患者人数,及早发现服用关键药物的患者,减少漏服剂量和潜在的伤害。药房技术员还能更早地确认患者的过敏状况,进一步减少急诊室内的伤害。 1.1. NICE 指南 (NG5)。药物优化:安全有效地使用药物以实现最佳疗效。2015 年 3 月 4 日发布。
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引用次数: 0
Antimicrobial Point Prevalence Survey in four Emergency Departments at Manchester University NHS Foundation Trust 曼彻斯特大学 NHS 基金会信托基金会四家急诊室的抗菌点流行率调查
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.026
F. M. Garraghan
Antimicrobial Point Prevalence Surveys (PPS) are a recognised tool to facilitate monitoring of compliance to an organisation’s antimicrobial stewardship (AMS) programme.1 Most PPS tools used within secondary care focus on prescribing of antimicrobials for in-patients. At Manchester University NHS Foundation Trust (MFT) PPS are carried out by clinical pharmacists across all inpatient ward areas. Antimicrobials are one of the most prescribed medicines in the emergency department2 (ED) yet, the current MFT PPS tool does not facilitate undertaking PPS in EDs. A new validated outpatient PPS tool3 from the Global Point Prevalence Survey (GPPS) was released earlier this year. To pilot the GPPS outpatient tool in the EDs at MFT to determine the level of compliance with the MFT antimicrobial guidelines within the EDs, estimate the total burden of antimicrobial use and describe types of infections and prescribed antimicrobials within the EDs. Following the GPPS outpatient protocol3 the four emergency departments (3 general EDs, and 1 paediatric ED) at MFT were assessed in a ten-day period during May 2023. Each ED was assessed continuously for a 4-hour timeslot on a weekday morning by an AMS pharmacist who retrieved the data from the EPIC electronic patient record system remotely. All patients who were allocated a room/bedspace on ED within the timeslot were audited, including patients who were not prescribed antimicrobials. Guideline compliance was checked with the MFT antimicrobial guidelines. The online GPPS data collection tool was used, generating a data download into an Excel spreadsheet for analysis. This study was a service evaluation and so did not require ethical approval. 180 patients were audited from 4 EDs yielding a total of 41 prescriptions for antimicrobials. 28/180 patients were prescribed one or more antimicrobial, with an overall antimicrobial prescribing rate of 15.5%. Prescribing was higher in the paediatric ED with a rate of 25%. 92.7% (38/41) of antimicrobials were prescribed intravenously (IV). Choice of antimicrobial was compliant in 38/41 (92.7%). Dose was compliant in 40/41 (97.6%). Duration of treatment was compliant in 39/41 (95.1%). Sepsis accounted for 48.8% of indications. 2/41 prescriptions were based on the C Reactive Protein (CRP) biomarker. Whilst the study was only conducted over a short time period, the findings suggested that overall compliance with the MFT antimicrobial guidelines was very good. The prescribing rate of 15.5% was low in comparison to the recent MFT inpatient PPS which showed a prescribing rate of 30%. There is a high rate of diagnosis of sepsis and prescribing of IV antimicrobials in comparison to orals which may be anticipated in the emergency setting. The GPPS outpatient audit tool provided an opportunity to do a baseline assessment within the EDs across MFT, providing data on prevalence of antimicrobial prescribing and compliance to the MFT guidelines. The GPPS audit to
抗菌药物点流行率调查(PPS)是一种公认的工具,有助于监测机构抗菌药物管理(AMS)计划的合规性1 。在曼彻斯特大学 NHS 基金会信托基金会(Manchester University NHS Foundation Trust,MFT),PPS 由临床药剂师在所有住院病房区域执行。抗菌药物是急诊科2 (ED)处方量最大的药物之一,但目前曼彻斯特大学 NHS 基金会信托基金会的 PPS 工具并不便于在急诊科开展 PPS。今年早些时候,全球点流行率调查(GPPS)发布了一个新的经过验证的门诊病人 PPS 工具3。 在港澳總部急症室試用GPPS門診工具,以確定急症室遵守港澳總部抗菌藥物指引的情況、估計使用抗菌藥物的總負擔,以及描述急症室的感染類別和處方抗菌藥物。 根据 GPPS 门诊协议3 ,在 2023 年 5 月的 10 天内对对外贸易部的 4 个急诊科(3 个普通急诊科和 1 个儿科急诊科)进行了评估。每位急诊科药剂师均在工作日上午的 4 小时时段内对每个急诊科进行连续评估,并从 EPIC 电子病历系统中远程检索数据。所有在该时段内被分配到急诊室病房/床位的患者都接受了审核,包括未被处方抗菌药物的患者。根据MFT抗菌药物指南对指南合规性进行检查。使用在线 GPPS 数据收集工具,将数据下载到 Excel 电子表格中进行分析。本研究是一项服务评估,因此无需获得伦理批准。 对 4 家急诊室的 180 名患者进行了审核,共开出 41 张抗菌药物处方。28/180 名患者被开具了一种或多种抗菌药物处方,抗菌药物总处方率为 15.5%。儿科急诊室的处方率较高,达到 25%。 92.7%的抗菌药物(38/41)是静脉注射(IV)。38/41(92.7%)人的抗菌药选择符合规定。40/41(97.6%)人符合剂量要求。39/41(95.1%)例符合治疗时间要求。败血症占适应症的 48.8%。2/41 的处方基于 C 反应蛋白 (CRP) 生物标志物。 虽然这项研究只进行了很短的时间,但研究结果表明,对 MFT 抗菌药物指南的总体遵守情况非常好。15.5%的处方率与最近进行的胃肠病治疗部住院病人抗菌药物处方率(PPS)相比偏低,后者显示处方率为 30%。与口服抗菌药相比,败血症的诊断率和静脉注射抗菌药的处方率较高,这在急诊环境中是可以预见的。 GPPS 门诊病人审计工具提供了在整个 MFT 的急诊室内进行基线评估的机会,提供了有关抗菌药物处方流行率和 MFT 指南合规性的数据。GPPS 审计工具无法审查急诊室内严重感染/败血症临床诊断的准确性,也无法审查静脉注射抗菌药物处方的适当性。应开展进一步研究,以确保急诊室对严重感染的临床诊断和静脉注射抗菌药物处方的适当性。 1.英格兰公共卫生局。Start Smart then Focus.英国医院抗菌药物管理工具包》(Antimicrobial Stewardship toolkit for English Hospitals)。2016. 2.Denny K,Appropriateness of antibiotic prescribing in the Emergency Department.,JAC,2019,vol 74 (2) P 515-520 3.全球点流行率调查,门诊模块。https://www.global-pps.com/wp-content/uploads/2023/05/Protocol-Global-PPS-outpatient-module_April2023-final.pdf
{"title":"Antimicrobial Point Prevalence Survey in four Emergency Departments at Manchester University NHS Foundation Trust","authors":"F. M. Garraghan","doi":"10.1093/ijpp/riad074.026","DOIUrl":"https://doi.org/10.1093/ijpp/riad074.026","url":null,"abstract":"Antimicrobial Point Prevalence Surveys (PPS) are a recognised tool to facilitate monitoring of compliance to an organisation’s antimicrobial stewardship (AMS) programme.1 Most PPS tools used within secondary care focus on prescribing of antimicrobials for in-patients. At Manchester University NHS Foundation Trust (MFT) PPS are carried out by clinical pharmacists across all inpatient ward areas. Antimicrobials are one of the most prescribed medicines in the emergency department2 (ED) yet, the current MFT PPS tool does not facilitate undertaking PPS in EDs. A new validated outpatient PPS tool3 from the Global Point Prevalence Survey (GPPS) was released earlier this year. To pilot the GPPS outpatient tool in the EDs at MFT to determine the level of compliance with the MFT antimicrobial guidelines within the EDs, estimate the total burden of antimicrobial use and describe types of infections and prescribed antimicrobials within the EDs. Following the GPPS outpatient protocol3 the four emergency departments (3 general EDs, and 1 paediatric ED) at MFT were assessed in a ten-day period during May 2023. Each ED was assessed continuously for a 4-hour timeslot on a weekday morning by an AMS pharmacist who retrieved the data from the EPIC electronic patient record system remotely. All patients who were allocated a room/bedspace on ED within the timeslot were audited, including patients who were not prescribed antimicrobials. Guideline compliance was checked with the MFT antimicrobial guidelines. The online GPPS data collection tool was used, generating a data download into an Excel spreadsheet for analysis. This study was a service evaluation and so did not require ethical approval. 180 patients were audited from 4 EDs yielding a total of 41 prescriptions for antimicrobials. 28/180 patients were prescribed one or more antimicrobial, with an overall antimicrobial prescribing rate of 15.5%. Prescribing was higher in the paediatric ED with a rate of 25%. 92.7% (38/41) of antimicrobials were prescribed intravenously (IV). Choice of antimicrobial was compliant in 38/41 (92.7%). Dose was compliant in 40/41 (97.6%). Duration of treatment was compliant in 39/41 (95.1%). Sepsis accounted for 48.8% of indications. 2/41 prescriptions were based on the C Reactive Protein (CRP) biomarker. Whilst the study was only conducted over a short time period, the findings suggested that overall compliance with the MFT antimicrobial guidelines was very good. The prescribing rate of 15.5% was low in comparison to the recent MFT inpatient PPS which showed a prescribing rate of 30%. There is a high rate of diagnosis of sepsis and prescribing of IV antimicrobials in comparison to orals which may be anticipated in the emergency setting. The GPPS outpatient audit tool provided an opportunity to do a baseline assessment within the EDs across MFT, providing data on prevalence of antimicrobial prescribing and compliance to the MFT guidelines. The GPPS audit to","PeriodicalId":14284,"journal":{"name":"International Journal of Pharmacy Practice","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139197889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A narrative analysis of patients’ experiences of taking medication for secondary prevention of acute myocardial infarction 对急性心肌梗死二级预防患者服药经历的叙事分析
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.053
H. Piekarz, P. Donyai
Following an acute myocardial infarction, patients are given a daily regime of five medications to prevent secondary cardiovascular events. However, adherence to these medications has been measured to be 66%1. Sub-optimal adherence leads to increased mortality, morbidity and associated healthcare system costs. There is a lack of qualitative research of this experience for these patients, and current interventions, such as Dossett trays and New Medicines Service interviews are based upon presumed difficulties, such as memory and physical medication issues. The aim of this study was to better understand patient’s experience of taking medication to prevent a further AMI, using a narrative analysis framework to describe their relationship with their medication and healthcare professionals. Following ethical approval (UREC 18/36), participants were recruited with inclusion criteria of adults taking medication following at least one previous episode of AMI. Following signed informed consent, semi-structured interviews were conducted with fifteen people from central and southern England. Interviews were conducted in person, online, or on the telephone and audio recorded. The recordings were transcribed verbatim and organised using NVivo software. A narrative analysis framework was used to organise themes within the whole of each participant’s story and then separated into narrative arcs and organised by theme2. The whole story analysis showed the differences between each participant’s story, and that each participant’s story contained varying complicating factors that were personal and specifically important to their lives. The presence of side effects was a complicating factor for most participants. The narrative arc analysis showed that initially, participants felt they began taking medication with little control, feeling compelled to follow their prescriber’s directions and ‘do what they were told’. They understood the benefit to their health, and quickly built routine into their lives. At the next stage, participants worked in collaboration with their prescriber. They had acquired knowledge and social support of non-prescribing professionals, which enabled them to recognise side effects, which they tolerated. Missed doses were viewed as insignificant, happening infrequently and balanced by a history of medication continuity. A crisis point was reached when side effects became unmanageable, where they sought help from their prescriber to change their medication. The desired stage to reach was stability, where participants continued to take medication, and found it simple, unnoticed, fitted into their life and monitored using biometric results. These participants were non-intentional non-adherers, and described how they successfully added a medication regime into their lives, the details of which could assist patients who find this process more difficult. They described personal and detailed stories, indicating that inter
急性心肌梗死发生后,患者每天需要服用五种药物来预防继发性心血管事件。然而,据测量,这些药物的依从性仅为 66%1 。未达到最佳依从性会导致死亡率、发病率和相关医疗系统成本的增加。目前还缺乏对这些患者用药体验的定性研究,而目前的干预措施,如多塞特托盘和新药服务访谈,都是基于假定的困难,如记忆力和身体用药问题。 本研究的目的是更好地了解患者服药预防再次发生急性心肌梗死的经历,采用叙事分析框架来描述他们与药物和医护人员之间的关系。 在获得伦理批准(UREC 18/36)后,研究人员开始招募参与者,其纳入标准为至少曾有过一次急性心肌梗塞发作后服药的成年人。在签署知情同意书后,我们对来自英格兰中部和南部的 15 人进行了半结构化访谈。访谈以面谈、在线访谈或电话访谈的形式进行,并进行了录音。录音被逐字转录,并使用 NVivo 软件进行整理。叙事分析框架用于组织每位参与者整个故事中的主题,然后将其分为叙事弧线,并按主题进行组织2。 对整个故事的分析表明,每位受试者的故事之间存在差异,而且每位受试者的故事都包含不同的复杂因素,这些因素都是个人的、对其生活特别重要的。对大多数参与者来说,副作用的存在是一个复杂因素。 叙事弧分析表明,起初,参与者认为他们在开始服药时几乎没有控制权,感觉自己不得不遵照处方医生的指示 "照做"。他们了解服药对健康的益处,并很快在生活中养成了习惯。在下一阶段,参与者与处方医生合作。他们获得了非处方专业人员的知识和社会支持,这使他们能够认识到副作用,并且能够忍受。漏服药物被认为是微不足道的,很少发生,而且有连续服药的历史。当副作用变得无法控制时,他们就会向处方医生寻求帮助,更换药物。希望达到的阶段是稳定阶段,即参与者继续服药,并发现服药简单,不被注意,与他们的生活融为一体,并使用生物测定结果进行监测。 这些参与者并非有意不坚持服药,他们描述了自己如何成功地将服药制度融入生活,其中的细节可以帮助那些在服药过程中遇到困难的患者。 他们描述了个人的详细故事,表明协助服药的干预措施适合患者个人的工作。他们所有叙述的主题都包括副作用的存在,对此,他们听从作为治疗决策者的处方医生的意见。 非处方医护人员被描述为在后期阶段提供社会支持,但药剂师有可能利用新药服务等服务,在 参与者认为缺乏控制的初期阶段提供更多支持。 1.Ma TT、Wong IC、Man KK、Chen Y、Crake T、Ozkor MA、Ding LQ、Wang ZX、Zhang L、Wei L.循证疗法对心血管疾病二级预防的效果:系统回顾与荟萃分析》。PLoS One.2019;14(1):e0210988. Ryan K, Bissell P, Morecroft C. 《疾病与用药叙事:药学实践研究中被忽视的主题/新方法》。第二部分:实践中的用药叙事。药学世界与科学》。2007 Aug;29:353-60.
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引用次数: 0
Outcomes and GP perceptions of reviewing patients at risk of harm from opioids 审查有可能受到阿片类药物伤害的患者的结果和全科医生的看法
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.067
M. Wilcock, M. Motta, L. Trevena
The Clinical Commissioning Group (CCG) Medicines Optimisation workplan for 2021-22 had a focus on reducing harm from opioids.1,2 In particular, asking GP practices to identify and review two cohorts of patients: those on a combination of oxycodone and amitriptyline or similar high-risk combinations, and those over the age of 65 prescribed fentanyl transdermal patches. Practices were then expected to consider actions on how to reduce the risk for patients and also to provide feedback to the CCG on how the reviews had progressed. We aimed to understand the outcomes, challenges and learning points experienced by practices in reviewing these patients. Sixty practices were invited to participate. A feedback form was received from each practice that completed either or both reviews (covering anonymised outcomes of each review, challenges encountered, and practice-level learning points / changes made). Quantitative data were collated for each action, and feedback comments were categorised into broad groups. No patient details were collected. As this project was a service evaluation, ethical approval was not required. Forty-three practices completed the review of the combination of oxycodone and amitriptyline, though 5 of these had no patients to review. Overall, 185 patients were identified. Of these, 21 (11%) patients had the combination prescribing ceased, 22 (12%) were commenced on a reduction plan, and another 46 (25%) have been made aware of the risk and to report respiratory symptoms. Forty-three practices completed the fentanyl review, though one of these had no patients to review. Overall, 272 patients over 65 years were identified with 64 (24%) invited for a review with their GP or other allied health professional, 39 (14%) patients were put on a fentanyl patch dose reduction plan, and 14 (5%) had prescribing ceased. Practices reported various difficulties encountered with these reviews, including patient engagement in making changes to their pain medication which patients are reluctant to reduce; counselling and raising awareness of long-term effects of opioids to help gain patient understanding; how to manage complex patients who had been stable on their regimen over many years; and that it was time consuming to regularly check in with the patient and plan reduction regimens. Changes made by practices included recording risks discussed with patient in their medical record for easier future review; ensuring regular reviews, including by practice-based pharmacists, of patients prescribed opioids; trying to make time to see patients face to face; raising awareness of the risks of prescribing amitriptyline alongside oxycodone e.g. serotonin syndrome; and recognising that a collaborative process and patient engagement is necessary. The actions undertaken by practices link into national recommendations,1 with some GP feedback similar to the challenges and opportunities to improve patient safety on opioid use as reported
临床委员会(CCG)2021-22 年药品优化工作计划的重点是减少阿片类药物的危害。1,2 特别是要求全科医生确定并审查两类患者:服用羟考酮和阿米替林组合或类似高风险组合的患者,以及 65 岁以上服用芬太尼透皮贴剂的患者。然后,医疗机构应考虑如何降低患者的风险,并就审查进展情况向 CCG 提供反馈。 我们的目的是了解实践在审查这些患者时所经历的结果、挑战和学习要点。 我们邀请了 60 家医疗机构参与。每家完成其中一项或两项审查的医疗机构都提交了一份反馈表(内容包括每次审查的匿名结果、遇到的挑战以及医疗机构层面的学习要点/做出的改变)。对每项行动的定量数据进行了整理,并将反馈意见分为几大类。没有收集患者的详细信息。由于该项目是一项服务评估,因此无需获得伦理批准。 43 家诊所完成了对羟考酮和阿米替林联合用药的审查,但其中 5 家诊所没有病人需要审查。总共确定了 185 名患者。其中,21 名患者(11%)停止了联合用药,22 名患者(12%)开始执行减量计划,另有 46 名患者(25%)已意识到风险并报告呼吸道症状。43 家诊所完成了芬太尼审查,但其中一家诊所没有病人需要审查。总体而言,共发现了 272 名 65 岁以上的患者,其中 64 人(24%)被邀请与他们的全科医生或其他专职医疗人员一起进行复查,39 人(14%)被列入芬太尼贴片减量计划,14 人(5%)被停止处方。 医疗机构报告了在这些审查过程中遇到的各种困难,包括患者不愿意减少的止痛药物的改变;咨询和提高对阿片类药物长期影响的认识,以帮助获得患者的理解;如何管理多年来一直稳定使用其治疗方案的复杂患者;以及定期检查患者和计划减量治疗方案耗费时间。医疗机构做出的改变包括:将与患者讨论过的风险记录在病历中,方便日后审查;确保定期审查阿片类药物处方的患者,包括由医疗机构的药剂师进行审查;尽量抽出时间与患者面对面交流;提高对阿米替林与羟考酮同时处方的风险(如血清素综合征)的认识;认识到合作过程和患者参与是必要的。 实践中采取的行动与国家建议1 相结合,一些全科医生的反馈意见与其他地方报道的改善阿片类药物使用患者安全的挑战和机遇相似。这项小规模研究的其他局限性包括:无法确定阿片类药物处方的减少是否总是符合临床需要,以及对实践反馈的依赖。 1.Taylor S, Annand F, Burkinshaw P, Greaves F, Kelleher M, Knight J, et al. Dependence and withdrawal associated with some prescribed medicines: an evidence review.英国公共卫生,伦敦。2019. 2.2. Regulation 28 Report to prevent future deaths.见 https://www.judiciary.uk/wp-content/uploads/2019/11/Graham-Saffery-2019-0301_Redacted.pdf(2023 年 3 月 20 日访问) 3.Punwasi R, de Kleijn L, Rijkels-Otters JBM, Veen M, Chiarotto A, Koes B. General practitioners' attitudes towards opioids for non-cancer pain: a qualitative systematic review. BMJ Open 2022;12:e054945.BMJ Open 2022; 12:e054945.
{"title":"Outcomes and GP perceptions of reviewing patients at risk of harm from opioids","authors":"M. Wilcock, M. Motta, L. Trevena","doi":"10.1093/ijpp/riad074.067","DOIUrl":"https://doi.org/10.1093/ijpp/riad074.067","url":null,"abstract":"The Clinical Commissioning Group (CCG) Medicines Optimisation workplan for 2021-22 had a focus on reducing harm from opioids.1,2 In particular, asking GP practices to identify and review two cohorts of patients: those on a combination of oxycodone and amitriptyline or similar high-risk combinations, and those over the age of 65 prescribed fentanyl transdermal patches. Practices were then expected to consider actions on how to reduce the risk for patients and also to provide feedback to the CCG on how the reviews had progressed. We aimed to understand the outcomes, challenges and learning points experienced by practices in reviewing these patients. Sixty practices were invited to participate. A feedback form was received from each practice that completed either or both reviews (covering anonymised outcomes of each review, challenges encountered, and practice-level learning points / changes made). Quantitative data were collated for each action, and feedback comments were categorised into broad groups. No patient details were collected. As this project was a service evaluation, ethical approval was not required. Forty-three practices completed the review of the combination of oxycodone and amitriptyline, though 5 of these had no patients to review. Overall, 185 patients were identified. Of these, 21 (11%) patients had the combination prescribing ceased, 22 (12%) were commenced on a reduction plan, and another 46 (25%) have been made aware of the risk and to report respiratory symptoms. Forty-three practices completed the fentanyl review, though one of these had no patients to review. Overall, 272 patients over 65 years were identified with 64 (24%) invited for a review with their GP or other allied health professional, 39 (14%) patients were put on a fentanyl patch dose reduction plan, and 14 (5%) had prescribing ceased. Practices reported various difficulties encountered with these reviews, including patient engagement in making changes to their pain medication which patients are reluctant to reduce; counselling and raising awareness of long-term effects of opioids to help gain patient understanding; how to manage complex patients who had been stable on their regimen over many years; and that it was time consuming to regularly check in with the patient and plan reduction regimens. Changes made by practices included recording risks discussed with patient in their medical record for easier future review; ensuring regular reviews, including by practice-based pharmacists, of patients prescribed opioids; trying to make time to see patients face to face; raising awareness of the risks of prescribing amitriptyline alongside oxycodone e.g. serotonin syndrome; and recognising that a collaborative process and patient engagement is necessary. The actions undertaken by practices link into national recommendations,1 with some GP feedback similar to the challenges and opportunities to improve patient safety on opioid use as reported","PeriodicalId":14284,"journal":{"name":"International Journal of Pharmacy Practice","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139202588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“I wasn’t interested until I actually had that consultation”: Exploring the acceptability of a community pharmacy-based hypertension visualisation intervention "在真正咨询之前,我并不感兴趣":探索社区药房高血压可视化干预的可接受性
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.013
S. Brown, I. Khan, P. Angel, B. Hallingberg, D. McRae, B. McDonnell, D. H. James
Hypertension affects around 30% of the UK population and is the leading modifiable cause of cardiovascular disease1. Despite available evidence-based treatments, nonadherence to antihypertensive medication is prevalent. Health psychology theory suggests that beliefs about a condition and its treatment influence health-related behaviours such as medication adherence through the formation of ‘illness representations’, a lay perception of the health threat. Accurate illness representations and an increased belief in the necessity for medication are associated with greater medication adherence2. Visualisation of the internal process of an illness has been shown to support the accuracy of illness representations3. ViSTA-BP (Visualisation to Support Treatment Adherence for High Blood Pressure) is a digital intervention used within a healthcare consultation, enabling individuals to visualise and conceptualise hypertension and the resulting changes to the circulatory system using real-time animations. The purpose is to support medication adherence through the improved understanding of hypertension and increased perception of medication necessity. To explore the acceptability of a community pharmacy-based hypertension visualisation intervention (ViSTA-BP) with community pharmacists and patients. Acceptability of ViSTA-BP was investigated in a community pharmacy setting in South Wales by conducting semi-structured qualitative interviews with pharmacists and patients. Ethical approval was granted by NHS Research Ethics Committee Wales (REC) 5 (20/WA/0280) and Cardiff Metropolitan University Ethics Committee (PGR-3806). Template analysis, a form of qualitative thematic analysis, was used to guide data interpretation. The Theoretical Framework of Acceptability (TFA) provided a lens through which to investigate acceptability, considering affective attitude towards the intervention burden, intervention coherence, ethicality, opportunity costs, perceived effectiveness and self-efficacy. Patients were purposely selected, incorporating a range of locations, adherence and treatment beliefs, thus minimising bias. Interviews were conducted with fifteen patients and eight pharmacists who provided feedback. Both groups demonstrated a positive attitude towards ViSTA-BP. Patients were both interested in and reassured by the intervention. They showed good intervention coherence, articulating an increased understanding of hypertension and suggesting patient groups that could benefit from ViSTA-BP. Pharmacists felt ViSTA-BP illustrated the necessity for medication, demonstrating that hypertension could be managed effectively. Patients and pharmacists were positive about ViSTA-BP’s potential for effectiveness. Patients felt it provided context for their understanding of hypertension and could prompt action. Pharmacists liked the visual elements, with ViSTA-BP providing a useful addition to their consultation ‘toolkit’. Patients felt that ViSTA-BP fit
高血压影响着英国约 30% 的人口,是心血管疾病的主要可改变病因1。尽管有循证治疗方法,但不坚持服用降压药的现象仍很普遍。健康心理学理论认为,对疾病及其治疗的信念会通过形成 "疾病表象"(一种对健康威胁的非专业看法)影响与健康相关的行为,如坚持服药。准确的疾病表征和对药物治疗必要性的更多信念与更高的药物治疗依从性相关2。对疾病内部过程的可视化已被证明有助于提高疾病表征的准确性3。 ViSTA-BP(支持坚持高血压治疗的可视化)是在医疗保健咨询中使用的一种数字干预措施,通过使用实时动画,使个人能够可视化和概念化高血压以及由此导致的循环系统变化。其目的是通过加深对高血压的理解和提高对药物治疗必要性的认识来支持坚持用药。 探索社区药剂师和患者对基于社区药房的高血压可视化干预(ViSTA-BP)的接受度。 通过对药剂师和患者进行半结构化定性访谈,调查南威尔士社区药房对 ViSTA-BP 的接受程度。该研究获得了威尔士国家医疗服务系统研究伦理委员会 (REC) 5 (20/WA/0280) 和卡迪夫城市大学伦理委员会 (PGR-3806) 的伦理批准。模板分析是定性专题分析的一种形式,用于指导数据解释。可接受性理论框架(TFA)为研究可接受性提供了一个视角,考虑了对干预负担的情感态度、干预一致性、伦理性、机会成本、感知有效性和自我效能。 对患者进行了有目的的选择,包括不同的地点、依从性和治疗信念,从而最大限度地减少偏差。 对 15 名患者和 8 名提供反馈意见的药剂师进行了访谈。 两组人都对 ViSTA-BP 持积极态度。患者对干预既感兴趣又放心。他们表现出良好的干预连贯性,阐明了对高血压的进一步了解,并提出了可从 ViSTA-BP 中受益的患者群体。药剂师认为,ViSTA-BP 说明了药物治疗的必要性,证明高血压可以得到有效控制。患者和药剂师对 ViSTA-BP 的潜在有效性持肯定态度。患者认为,ViSTA-BP 为他们了解高血压提供了背景,可以促使他们采取行动。药剂师喜欢视觉元素,ViSTA-BP 为他们的咨询 "工具包 "提供了有益的补充。 患者认为 ViSTA-BP 非常适合社区药房的环境。干预的可及性和主持人的知识是关键;患者认为干预的持续时间是可以接受的。药剂师认为,ViSTA-BP 适合他们目前的工作。然而,社区药房工作人员不断演变的角色以及相互竞争的工作负担所带来的时间压力,都对 ViSTA-BP 在社区药房环境中的未来可行性产生了不确定性。 患者和药剂师对 ViSTA-BP 都持肯定态度,认为个性化互动视觉效果可以吸引观众,并通过基于视觉的交流让他们对高血压有概念。然而,药剂师对威尔士社区药房合同框架所支持的未来角色的看法以及员工的时间限制为未来的实施提供了潜在的障碍。 1.McDonnell BJ、Rees E、Cockcroft JR、Beaney T、Clayton B、Kieu P Le 等:《2019 年五月测量月:英国和爱尔兰共和国血压筛查结果分析》。欧洲听力杂志,增刊。2021;23(supplement B):B147-50. 2.Hagger MS, Orbell S. The Common sense model of illness self-regulation: a conceptual review and proposed extended model.Health Psychol Rev [Internet].2022;16(3):347-77.Available from: https://doi.org/10.1080/17437199.2021.1878050 3.Jones ASK, Ellis CJ, Nash M, Stanfield B, Broadbent E. Using Animation to Improve Recovery from Acute Coronary Syndrome:随机试验》。Ann Behav Med.2016 Feb 1;50(1):108-18.
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引用次数: 0
An innovative method to identify educational need regarding depression and anxiety as an under-recognised side effect of anti-TNF medicines 用创新方法确定教育需求,了解抑郁和焦虑是抗肿瘤坏死因子药物未得到充分认识的副作用
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.059
D. Rosembert, F. Eldridge, T. Raine, A. St Clair-Jones
Depression and anxiety (D&A) in chronic autoimmune conditions such as Inflammatory Bowel Disease (IBD), Rheumatoid arthritis (RA), Psoriatic arthritis (PsA), and Psoriasis (PsO) is common, with patients twice as likely to suffer from it.1 Biologic medicines are increasingly used in autoimmune conditions and are prescribed only by secondary care. Patients initiated on biologic medicines, specifically anti-TNF, can report depression and anxiety as related side effects listed as common in the summary of product characteristics2,3 and may not get investigated for this side effect when visiting GP practices and hospital reviews. This could lead to unnecessary use of psychological or psychopharmacological treatment and a poor patient experience of biologics therapies. To explore healthcare professionals’ understanding of the potential adverse effects of anti-TNF medicines including D&A symptoms in patients who present to primary care. A Twitter poll was used on the social media platform Twitter to raise the question; ‘GP’s, practice nurses and pharmacists, if your patient with IBD, RA, PsA, PsO etc. presents with symptoms of depression, do you check if they are prescribed a hospital only biologic such as anti-TNF (depression listed as a common side effect) as a possible cause?’. The Likert scale, Always, Sometimes, Never, Didn’t occur to me was used to elicit answers. The question was open for a 3 day window in May 2021, and then repeated in February 2022. A national webinar (advertised for anyone to attend) was held to present these results, and two further questions were asked of the participants using Slido; ‘are you surprised at this figure of 60%?’ and ‘do you think that something needs to be done about this?’ with a yes or no response option. Ethical approval was not required for this service evaluation. The results from the Twitter poll in May 2021, had 38 votes, the summary of the responses were 2(5%) [Always], 5 (13%) [Sometimes], 8 (21%) [Never] and 23 (61%) [Didn’t occur to me]. Results from the second poll in February 2022 had 217 votes and responses were 27(12%) [Always], 33(15%) [Sometimes], 23(10%) [Never] and 134(63%) [Didn’t occur to me]. Of the 150 people who attended the webinar, 99 (66%) were not surprised and 100% thought something needs to be done about it. This innovative if not scientific method (Twitter and Slido) of surveying HCPs, identified a considerable lack of awareness of the D&A side effects of biologics and uncovered a gap in monitoring of vulnerable patients. This suggests the need for education of HCPs about this issue. Awareness can also be increased through patient education, appropriate counselling, and patient information leaflets. Empowering patients to ask if the hospital prescribed medication is on their GP medication list and a potential cause. Twitter is a novel way to gain insight from colleagues, however responses from HCPs only are not guaranteed. This approach is a model to sc
抑郁和焦虑(D&A)在炎症性肠病(IBD)、类风湿性关节炎(RA)、银屑病关节炎(PsA)和牛皮癣(PsO)等慢性自身免疫性疾病中很常见,患者患上抑郁和焦虑的几率是其他疾病的两倍1。开始使用生物制剂药物(尤其是抗肿瘤坏死因子)的患者可能会报告抑郁和焦虑,这些副作用在产品特征概要中被列为常见副作用2,3 ,但在全科医生诊所就诊和医院复查时可能不会对这些副作用进行调查。这可能导致不必要地使用心理或精神药物治疗,以及患者对生物制剂疗法的不良体验。 探讨医护人员对抗肿瘤坏死因子药物潜在不良反应的理解,包括对初级医疗患者的D&A症状的理解。 我们在社交媒体平台 Twitter 上发起了一项 Twitter 民意调查,提出了这样一个问题:"全科医生、执业护士和药剂师,如果您的 IBD、RA、PsA、PsO 等患者出现抑郁症状,您是否会检查他们是否在医院开具了抗肿瘤坏死因子等生物制剂处方(抑郁症被列为常见副作用)作为可能的原因?该问题采用李克特量表("总是"、"有时"、"从不"、"我没想过")得出答案。该问题在 2021 年 5 月开放 3 天,然后在 2022 年 2 月重复。为了展示这些结果,还举行了一次全国性的网络研讨会(任何人都可参加),并使用 Slido 向参与者提出了两个问题:"您对 60% 这一数字感到惊讶吗?这项服务评估无需获得伦理批准。 2021 年 5 月在 Twitter 上进行的投票结果显示,共有 38 人投票,回答摘要分别为:2 人(5%)[总是]、5 人(13%)[有时]、8 人(21%)[从不]和 23 人(61%)[没想过]。2022 年 2 月的第二次投票结果显示,共有 217 人投票,回答为 27 人(12%)[总是]、33 人(15%)[有时]、23 人(10%)[从不]和 134 人(63%)[我没想过]。在参加网络研讨会的 150 人中,99 人(66%)对此并不感到惊讶,100% 的人认为需要对此采取一些措施。 这种创新性的调查方法(Twitter 和 Slido)即使不科学,也能发现人们对生物制剂的 D&A 副作用相当缺乏认识,并揭示了在监测易感患者方面存在的差距。这表明有必要对主治医师进行相关教育。还可以通过患者教育、适当的咨询和患者信息宣传单来提高患者的认识。让患者有能力询问医院开具的药物是否在其全科医生的用药清单上,这也是一个潜在的原因。推特是一种从同事处获得见解的新方法,但并不能保证只得到 HCP 的回复。这种方法是项目可行性范围的一种模式,但只能捕捉到 Twitter 的用户,并取决于个人网络的规模和转发 Twitter 的参与程度。 1.Wells KB, Golding JM, Burnam MA.有慢性病和无慢性病普通人群中的精神障碍样本。Am J Psychiatry.1988 Aug;145(8):976-81 2.Amgevita 40mg 注射用预灌笔溶液。电子药品汇编。搜索结果 - (emc) (medicines.org.uk) 2022。(2023 年 5 月访问) 3.Eldridge F, Raine T, Understanding and addressing the psychological burden of IBD, Journal of Crohn's and colitis, 2021, 1-2
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引用次数: 0
Understanding the causes of preventable medication incidents for patients with mental illness in primary care 了解基层医疗机构中精神疾病患者可预防用药事故的原因
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.008
M. J. Ayre, P. J. Lewis, D. L. Phipps, R. N. Keers
A recent scoping review has highlighted that whilst patients with mental illness are commonly affected by medication errors and preventable adverse drug events in primary care, there were limited data regarding their causes1. By understanding why these preventable events occur, targeted interventions can be developed. To understand the nature and contributory factors that lead to medication errors and preventable adverse drug events amongst patients with mental illness in primary care. This study used a qualitative design. A researcher remotely interviewed 26 healthcare professionals (14 pharmacists, 5 GPs, 5 nurses, 2 psychiatrists) working in primary care between June-November 2022, guided by the critical incident technique. Professionals were recruited via social media, research team networks, and snowballing. Data were analysed using the framework method and any data that involved speculation as to the causes of errors was not included. The data were organised into themes based on the London protocol error framework, which describes the contributory factors leading to care delivery problems2. Themes generated were validated by other members of the research team and a patient advisory group. This study was approved by the University of Manchester Ethics Committee 1 (reference 2022-13735-23555). Forty-three medication errors and twelve preventable adverse drug events were discussed during interview. Prescribing errors were discussed most commonly (n=24) and administration errors least commonly (n=4). Six contributory factors were identified which were: the individual (staff) (n=37); the work environment (n=31); the teams/interfaces (n=28); the organisation and management (n=24); the patient (n=23); and the task and technology (n=15). Primary care clinicians reported a lack of knowledge regarding psychotropics and mental illness which accompanied diffusion of responsibility. The responsibilities of staff were also confused by limited clinical information communicated between teams and across care interfaces. Service demand was reported to exceed capacity, creating stress for the staff, as well as limiting the time available for staff to undergo training. Complicated patient lifestyles and behavioural challenges were reported as unique contributory factors. Lack of knowledge amongst primary care clinicians regarding psychotropics and mental illness was a key issue. This was exacerbated by a mental health service structure placing considerable pressure on primary care leaving clinicians to support patients with needs perceived to be outside their areas of confidence and competence. There is a need to support this workforce by upskilling them to effectively manage patients by addressing the educational needs regarding neuropharmacology and communication skills. These changes may have a positive effect in reducing error rates for this patient group in primary care. Study limitations include recall bias, social desirabilit
最近的一项范围界定审查强调,虽然精神疾病患者通常会受到初级医疗中用药错误和可预防药物不良事件的影响,但有关其原因的数据却十分有限1。通过了解这些可预防事件发生的原因,可以制定有针对性的干预措施。 本研究旨在了解导致基层医疗机构中精神病患者用药错误和可预防药物不良事件的性质和诱因。 本研究采用定性设计。2022 年 6 月至 11 月期间,在关键事件技术的指导下,一名研究人员对 26 名在基层医疗机构工作的医护人员(14 名药剂师、5 名全科医生、5 名护士和 2 名精神科医生)进行了远程访谈。专业人员是通过社交媒体、研究团队网络和滚雪球的方式招募的。数据采用框架法进行分析,任何涉及错误原因推测的数据都不包括在内。数据根据伦敦协议错误框架组织成主题,该框架描述了导致护理服务问题的促成因素2。研究小组的其他成员和患者咨询小组对所产生的主题进行了验证。本研究获得了曼彻斯特大学伦理委员会 1 的批准(参考文献 2022-13735-23555)。 访谈中讨论了 43 个用药错误和 12 个可预防的药物不良事件。其中处方错误最多(24 例),用药错误最少(4 例)。确定了六个促成因素:个人(员工)(37 人);工作环境(31 人);团队/界面(28 人);组织和管理(24 人);患者(23 人);任务和技术(15 人)。基层医疗机构的临床医生表示,他们缺乏精神药物和精神疾病方面的知识,因此责任分散。团队之间和医疗界面之间交流的临床信息有限,也混淆了工作人员的职责。据报告,服务需求超过了服务能力,给工作人员造成了压力,也限制了工作人员接受培训的时间。据报告,病人复杂的生活方式和行为挑战是独特的促成因素。 初级保健临床医生对精神药物和精神疾病缺乏了解是一个关键问题。心理健康服务结构给基层医疗机构带来了巨大压力,使临床医生不得不为那些被认为超出了他们的信心和能力范围的病人提供支持,从而加剧了这一问题。因此,有必要通过提高他们的技能来支持这支队伍,通过解决神经药理学和沟通技巧方面的教育需求来有效地管理病人。这些改变可能会对降低基层医疗机构中这一患者群体的错误率产生积极影响。研究的局限性包括回忆偏差、社会可取性偏差,以及所讨论的大多数错误是由一连串事件中的另一位临床医生所犯,因此可能会遗漏一系列事件中的关键细节。这是第一项针对基层医疗机构中精神疾病患者可预防用药事件的性质和促成因素的研究。未来的研究应侧重于从患者的角度来探讨这一主题,以更好地了解可预防用药事件的成因。 1.Ayre M, Lewis P, Keers R. Understanding the medication safety challenges for patients with mental illness in primary care: a scoping review.BMC Psychiatry.2023; In Press. 2.Taylor-Adams S, Vincent C. Systems analysis of clinical incidents: the London protocol.临床风险》。2004;10(6):211-20.
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引用次数: 0
Development and feasibility study of a community pharmacy intervention to support self-management of patients with type 2 diabetes, in Cyprus 在塞浦路斯开展社区药房干预措施的开发和可行性研究,以支持 2 型糖尿病患者的自我管理
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.052
A. Pavlidou, F. Smith, C. Whittlesea
The pharmacists’ role has evolved over the past years towards a more clinical role to support patients in managing various prevalent health conditions.1 Cyprus had one of the highest prevalence of diabetes among other European countries in 2021.2 Motivational interviewing has been shown to be an effective tool in consultations.3 In recent years there has been increasing interest in the potential of mobile technologies in health care. However, effective implementation, management, and evaluation of those interventions aiming to improve type 2 diabetes self-management are still being researched. The aim of this study was to design and implement a mobile health intervention delivered by a pharmacist applying motivational interviewing techniques, aiming to improve the self-management of type 2 diabetes patients. Then, assess primarily the feasibility and acceptability of the interventions and, secondarily, the participants' medication adherence and self-care activity. Type 2 diabetes patients visiting a diabetes clinic in Cyprus were recruited. The intervention included: online communication with the pharmacist, tracking & uploading blood glucose readings, graphical reports, reminders, education, and optimization of pharmacotherapy delivered over an initial face-to-face consultation and up to 3 follow-up telephone appointments at 6-8 weeks intervals. Feasibility was measured by recruitment & retention, use & workability of the intervention, and basic costs. Participants’ & healthcare professionals’ acceptability was assessed via two semi-structured interview schedules based on the Theoretical Framework of Acceptability (Sekhon et al., 2017). Participants’ medication adherence and self-care activity were assessed by Diabetes Self-Care Activities Questionnaire - Greek version before and after the intervention. The study obtained ethical approval from the Cyprus National Bioethics Committee (27/11/2019, reference number EEBK ΕΠ 2019.01.202), the Cyprus Ethics Committee (05/04/2020, reference number 01/20) and the UCL Research Ethics Committee (28/04/2020, reference number Z6364106/2020/04/129). Twenty-seven patients agreed to participate, of whom 22 completed the intervention. From the available services, all participants agreed to use online communication, chose education, and the review of patients’ medications. A barrier to the intervention was the pharmacist accessing patients’ data, as HbA1c was accessible in 69% of participants and blood glucose in 90%. Based on study findings, participants valued the motivational interview and pharmacist approach, while healthcare professionals highlighted the benefits of pharmacy service, specifically medication adherence. Participants reported improvements in self-care during the study period in three out of five domains assessed in the DSCAQ– Greek version (blood sugar testing, healthy eating, and foot care), whereas adherence to diabetes medications and physical activity remained the same
1 2021 年,塞浦路斯是欧洲其他国家中糖尿病发病率最高的国家之一。2 激励性访谈已被证明是一种有效的咨询工具。3 近年来,人们对移动技术在医疗保健领域的潜力越来越感兴趣。然而,对这些旨在改善 2 型糖尿病自我管理的干预措施的有效实施、管理和评估仍在研究之中。 本研究的目的是设计并实施一项由药剂师应用动机访谈技术提供的移动医疗干预措施,旨在改善 2 型糖尿病患者的自我管理。然后,主要评估干预措施的可行性和可接受性,其次评估参与者的服药依从性和自我护理活动。 研究人员招募了在塞浦路斯一家糖尿病诊所就诊的 2 型糖尿病患者。干预措施包括:与药剂师在线交流、跟踪和上传血糖读数、图形报告、提醒、教育和优化药物治疗,通过首次面对面咨询和多达 3 次的电话随访进行,每次间隔 6-8 周。可行性通过招募和保留、干预措施的使用和可操作性以及基本成本来衡量。根据可接受性理论框架(Sekhon et al.)干预前后,参与者的用药依从性和自我护理活动由糖尿病自我护理活动问卷(希腊语版)进行评估。该研究获得了塞浦路斯国家生物伦理委员会(27/11/2019,参考编号 EEBK ΕΠ 2019.01.202)、塞浦路斯伦理委员会(05/04/2020,参考编号 01/20)和 UCL 研究伦理委员会(28/04/2020,参考编号 Z6364106/2020/04/129)的伦理批准。 27 名患者同意参与,其中 22 人完成了干预。从现有服务来看,所有参与者都同意使用在线交流、选择教育和审查患者用药。药剂师访问患者数据是干预的一个障碍,因为 69% 的参与者可以访问 HbA1c,90% 的参与者可以访问血糖。根据研究结果,参与者重视动机访谈和药剂师的方法,而医护人员则强调了药学服务的益处,特别是坚持用药。在希腊语版 DSCAQ 评估的五个领域中,有三个领域(血糖检测、健康饮食和足部护理)的自我护理情况有所改善,而糖尿病药物治疗和体育锻炼的依从性则保持不变。 尽管由于这是一项可行性研究,因此研究结果不具有统计学意义,但有迹象表明,这种以证据为基础的个性化干预措施可以为糖尿病患者提供全面支持。这项研究的局限性在于,制定和评估干预措施的人与实施干预措施的人是同一个人。不过,研究结果表明了该干预措施对患者和医护人员的潜在价值。研究还提供了相关信息,以支持将该干预措施纳入塞浦路斯医疗保健系统和其他类似环境。 1.皇家药学协会(RPS)。改善对长期病患者的护理。[互联网]。伦敦;2016 年 [2023 年 1 月 9 日访问]。网址:https://www.rpharms.com/Portals/0/RPS%20document%20library/Open%20access/Policy/LTC%20-%20England.pdf。 2.国际糖尿病联合会(IDF)。糖尿病图谱第 10 版。[Internet].比利时布鲁塞尔;2021 年 [2023 年 2 月 23 日访问]。网址:http://diabetesatlas.org/IDF_Diabetes_Atlas_8e_interactive_EN/。 3.Salimi, C., Momtazi, S., Zenuzian, S. A review on effectiveness of motivational interviewing in the management of diabetes mellitus.JPCPY.2016; 5(4):00294. doi: 10.15406/jpcpy.2016.05.00294.
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引用次数: 0
Beyond the boundaries of ward-based services – exploring the scope of “non-traditional” clinical pharmacy practice in a tertiary referral teaching hospital 超越病房服务的界限--探索一家三级转诊教学医院的 "非传统 "临床药学实践范围
IF 1.8 Q2 Medicine Pub Date : 2023-11-30 DOI: 10.1093/ijpp/riad074.016
C. Cheng
Hospital clinical pharmacy practice in the UK has developed beyond traditional boundaries of ward-based inpatient services. Royal Pharmaceutical Society Hospital Pharmacy Standards recommend pharmacy team members are integrated into multidisciplinary teams across the organisation to ensure safe and appropriate medicines use whatever the setting1. Pharmacy professionals provide pharmaceutical care and specialist services in outpatient and ambulatory settings and through participation in multidisciplinary team (MDT) meetings. Within the outpatient setting, research typically focusses on single outpatient clinics within specific disciplines, little evidence describes the overall contribution to patient care across whole pharmacy services2. To describe the scope of clinical pharmacy services occurring beyond traditional ward-based services in a tertiary hospital; including quantification of outpatient clinics and MDT meetings provided by pharmacy professionals. The Deputy Chief Pharmacist invited clinical Principal Pharmacists to participate in semi-structured interviews exploring the scope of “non-traditional” services across the Trust during March 2023. Non-traditional services were defined as direct clinical care outside of ward-based inpatient clinical pharmacy services. Indirect clinical care activities such as guideline writing, drug expenditure and governance activities were excluded. Inpatient board rounds/ward rounds and any service not currently provided due to vacancy were excluded. Participants were asked to quantify services provided, advise who provided the services and to describe contributions provided by the pharmacy team. The study was deemed service evaluation and ethical approval waived. 100% invited pharmacists participated. Pharmacists attended and contributed to over 150 MDT meetings monthly across 24 sub-specialities; 80% were for outpatients. In tertiary/quaternary services, these frequently covered patients beyond local geography. MDT meetings were typically attended by specialist, principal or consultant pharmacists. Common contributions included: provision of pro-active advice/responding to queries; medicines optimisation; monitoring; income or compliance assurance; prescribing/deprescribing. Specialist pharmacists provided 80-100 outpatient clinic sessions across 17 sub-specialities through a mix of face-to-face and virtual appointments, advanced pharmacy technicians provided on-treatment and counselling clinics. Activities included: initiation, monitoring, adjustment and cessation of medicines; patient counselling and MDT referral. Medicines prescribed were typically high cost, complex and higher risk. Pharmacists prescribed and clinically verified homecare medicines and provided ongoing annual review of outpatient medicines, including prescribing/deprescribing. Teams described medicines reconciliation and counselling in ambulatory haematology settings, off-site units and infusion suites. The team or
英国的医院临床药学实践已经超越了以病房为基础的住院服务的传统界限。英国皇家药学会《医院药学标准》建议将药学团队成员纳入整个组织的多学科团队,以确保在任何环境下都能安全、合理地使用药物1。药学专业人员通过参与多学科团队 (MDT) 会议,在门诊和非住院环境中提供药物护理和专科服务。在门诊环境中,研究通常集中在特定学科的单个门诊诊所,很少有证据说明整个药学服务对患者护理的整体贡献2。 为了描述一家三甲医院在传统病房服务之外的临床药学服务范围,包括药学专业人员提供的门诊和 MDT 会议的量化。 副总药剂师邀请临床首席药剂师参加半结构式访谈,探讨 2023 年 3 月期间信托基金内 "非传统 "服务的范围。非传统服务被定义为病房住院临床药学服务之外的直接临床护理。指南撰写、药品支出和管理活动等间接临床护理活动不包括在内。住院病人委员会查房/前去查房以及因职位空缺而未提供的任何服务均不包括在内。要求参与者对所提供的服务进行量化,告知提供服务的人员,并描述药学团队做出的贡献。这项研究被视为服务评估,因此免于伦理审批。 100%的受邀药剂师参与了研究。药剂师参加了 24 个亚专科每月举行的 150 多次 MDT 会议,并做出了贡献;其中 80% 是针对门诊患者的。在三级/四级服务机构中,这些会议经常覆盖当地以外的患者。MDT 会议通常由专科药剂师、首席药剂师或顾问药剂师参加。常见的贡献包括:提供积极主动的建议/回答询问;药品优化;监测;收入或合规性保证;处方/处方。专科药剂师通过面对面和虚拟预约相结合的方式,为 17 个亚专科提供 80-100 次门诊服务,高级药剂技师则提供治疗和咨询门诊服务。活动包括:开始使用、监测、调整和停药;病人咨询和多学科小组转诊。处方药物通常成本高、复杂且风险较高。药剂师开具家庭护理药品处方并进行临床验证,同时对门诊药品进行持续的年度审查,包括开具处方/处方。团队介绍了在非住院血液科、非住院部和输液室进行的药品协调和咨询。团队为需要在家接受抗菌治疗的患者组织、优化并提供建议和咨询。临床药剂师和药剂技师为患者、内部和外部医护人员提供药品信息。 这项研究证明,在一家三级教学医院中,临床药学实践的范围已经超越了传统病房服务的界限。本研究仅限于一家机构,具体的临床药学活动和服务成果并未完全量化。对 "非传统 "门诊和非住院环境中临床药学活动的正式整理是有限的,因为医院药学的活动数据收集表通常是在传统病房药学服务中验证的。我们建议开展进一步研究,验证活动收集工具,以便为医院信托基金内部和医院信托基金之间在门诊和非住院环境中提供服务的临床药学专业人员的活动制定基准。 1.英国皇家药学会,《医院药学实践专业标准》,2022 年 11 月。通过 https://www.rpharms.com/recognition/setting-professional-standards/hospital-pharmacy-professional-standards 2023 年 5 月访问 2.Snoswell CL, Draper MJ, Barras M. An evaluation of pharmacist activity in hospital outpatient clinics.J. Pharm.Pract.J. Pharm. Pract. Res, 2021, 51(4), 328-332. https://doi.org/10.1002/jppr.1729
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引用次数: 0
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International Journal of Pharmacy Practice
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