Pub Date : 2024-05-23DOI: 10.1186/s40942-024-00558-0
Zuzana Anwarzai Sulavikova, Zuzana Sustykevicova, Marek Kacerik, Vladimir Krasnik
Background: The aim of this study is to evaluate near and distance visual acuity (VA) and their correlation with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) outcomes in patients with diabetic macular edema (DME) and macular edema due to retinal vein occlusion (RVO) treated with aflibercept.
Methods: In this prospective study, we included 87 eyes of patients diagnosed with DME (n = 61) and RVO (n = 26), who received aflibercept treatment and were followed until the 8th injection. Near VA was examined on the 1st, 2nd, 3rd, 4th, 6th, and 8th injection, and patients completed the NEI VFQ-25 on the 1st, 4th, and 8th aflibercept injection.
Results: The mean near VA at baseline in all eyes was 0.89 ± 0.12 logMAR. With every administration, there was a statistically significant improvement; on the 4th (0.70 ± 0.19; p = 0.000) and the 8th application (0.60 ± 0.19; p = 0.000). At baseline, the mean NEI VFQ-25 total score was 71 ± 14%, and improved to 81 ± 13% (p = 0.000) on the 8th injection. The most significant score gain was recorded in the near VA subscale (+ 20 ± 14%, p = 0.000). There was no statistically significant difference between DME and RVO group in the questionnaire or near VA outcomes.
Conclusion: Aflibercept treatment resulted in a remarkable improvement of near vision by 4 lines of logMAR optotype after the 8th application. The near vision questionnaire subscale, initially scoring the lowest, exhibited the greatest gain during the treatment period. This underscores the importance of near vision and reading ability for patients with DME and RVO.
{"title":"Near vision in patients with DME and RVO treated with aflibercept and correlation with NEI VFQ-25 questionnaire.","authors":"Zuzana Anwarzai Sulavikova, Zuzana Sustykevicova, Marek Kacerik, Vladimir Krasnik","doi":"10.1186/s40942-024-00558-0","DOIUrl":"10.1186/s40942-024-00558-0","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study is to evaluate near and distance visual acuity (VA) and their correlation with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) outcomes in patients with diabetic macular edema (DME) and macular edema due to retinal vein occlusion (RVO) treated with aflibercept.</p><p><strong>Methods: </strong>In this prospective study, we included 87 eyes of patients diagnosed with DME (n = 61) and RVO (n = 26), who received aflibercept treatment and were followed until the 8th injection. Near VA was examined on the 1st, 2nd, 3rd, 4th, 6th, and 8th injection, and patients completed the NEI VFQ-25 on the 1st, 4th, and 8th aflibercept injection.</p><p><strong>Results: </strong>The mean near VA at baseline in all eyes was 0.89 ± 0.12 logMAR. With every administration, there was a statistically significant improvement; on the 4th (0.70 ± 0.19; p = 0.000) and the 8th application (0.60 ± 0.19; p = 0.000). At baseline, the mean NEI VFQ-25 total score was 71 ± 14%, and improved to 81 ± 13% (p = 0.000) on the 8th injection. The most significant score gain was recorded in the near VA subscale (+ 20 ± 14%, p = 0.000). There was no statistically significant difference between DME and RVO group in the questionnaire or near VA outcomes.</p><p><strong>Conclusion: </strong>Aflibercept treatment resulted in a remarkable improvement of near vision by 4 lines of logMAR optotype after the 8th application. The near vision questionnaire subscale, initially scoring the lowest, exhibited the greatest gain during the treatment period. This underscores the importance of near vision and reading ability for patients with DME and RVO.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-23DOI: 10.1186/s40942-024-00547-3
Mia Karabeg, Goran Petrovski, Silvia Nw Hertzberg, Maja Gran Erke, Dag Sigurd Fosmark, Greg Russell, Morten C Moe, Vallo Volke, Vidas Raudonis, Rasa Verkauskiene, Jelizaveta Sokolovska, Inga-Britt Kjellevold Haugen, Beata Eva Petrovski
Background: Diabetic retinopathy (DR) is the leading cause of adult blindness in the working age population worldwide, which can be prevented by early detection. Regular eye examinations are recommended and crucial for detecting sight-threatening DR. Use of artificial intelligence (AI) to lessen the burden on the healthcare system is needed.
Purpose: To perform a pilot cost-analysis study for detecting DR in a cohort of minority women with DM in Oslo, Norway, that have the highest prevalence of diabetes mellitus (DM) in the country, using both manual (ophthalmologist) and autonomous (AI) grading. This is the first study in Norway, as far as we know, that uses AI in DR- grading of retinal images.
Methods: On Minority Women's Day, November 1, 2017, in Oslo, Norway, 33 patients (66 eyes) over 18 years of age diagnosed with DM (T1D and T2D) were screened. The Eidon - True Color Confocal Scanner (CenterVue, United States) was used for retinal imaging and graded for DR after screening had been completed, by an ophthalmologist and automatically, using EyeArt Automated DR Detection System, version 2.1.0 (EyeArt, EyeNuk, CA, USA). The gradings were based on the International Clinical Diabetic Retinopathy (ICDR) severity scale [1] detecting the presence or absence of referable DR. Cost-minimization analyses were performed for both grading methods.
Results: 33 women (64 eyes) were eligible for the analysis. A very good inter-rater agreement was found: 0.98 (P < 0.01), between the human and AI-based EyeArt grading system for detecting DR. The prevalence of DR was 18.6% (95% CI: 11.4-25.8%), and the sensitivity and specificity were 100% (95% CI: 100-100% and 95% CI: 100-100%), respectively. The cost difference for AI screening compared to human screening was $143 lower per patient (cost-saving) in favour of AI.
Conclusion: Our results indicate that The EyeArt AI system is both a reliable, cost-saving, and useful tool for DR grading in clinical practice.
背景:糖尿病视网膜病变(DR)是导致全球劳动适龄人口成人失明的主要原因,而早期发现是可以预防的。建议定期进行眼科检查,这对发现危及视力的糖尿病视网膜病变至关重要。目的:在挪威奥斯陆开展一项成本分析试点研究,利用人工(眼科医生)和自主(人工智能)分级,对该国糖尿病(DM)发病率最高的少数民族女性糖尿病患者队列进行检测。据我们所知,这是挪威第一项在DR视网膜图像分级中使用人工智能的研究:2017年11月1日少数民族妇女节当天,挪威奥斯陆市对33名18岁以上确诊患有糖尿病(T1D和T2D)的患者(66只眼睛)进行了筛查。在筛查结束后,由眼科医生使用EyeArt自动DR检测系统2.1.0版(EyeArt, EyeNuk, CA, USA)自动进行DR分级。分级基于国际临床糖尿病视网膜病变(ICDR)严重程度量表[1],检测是否存在可转诊的 DR。两种分级方法都进行了成本最小化分析:33名女性(64只眼睛)符合分析条件。结果:33 名女性(64 只眼睛)符合分析条件,评分者之间的一致性非常好:0.98(P我们的研究结果表明,EyeArt AI 系统是临床实践中用于 DR 分级的可靠、节约成本且有用的工具。
{"title":"A pilot cost-analysis study comparing AI-based EyeArt® and ophthalmologist assessment of diabetic retinopathy in minority women in Oslo, Norway.","authors":"Mia Karabeg, Goran Petrovski, Silvia Nw Hertzberg, Maja Gran Erke, Dag Sigurd Fosmark, Greg Russell, Morten C Moe, Vallo Volke, Vidas Raudonis, Rasa Verkauskiene, Jelizaveta Sokolovska, Inga-Britt Kjellevold Haugen, Beata Eva Petrovski","doi":"10.1186/s40942-024-00547-3","DOIUrl":"10.1186/s40942-024-00547-3","url":null,"abstract":"<p><strong>Background: </strong>Diabetic retinopathy (DR) is the leading cause of adult blindness in the working age population worldwide, which can be prevented by early detection. Regular eye examinations are recommended and crucial for detecting sight-threatening DR. Use of artificial intelligence (AI) to lessen the burden on the healthcare system is needed.</p><p><strong>Purpose: </strong>To perform a pilot cost-analysis study for detecting DR in a cohort of minority women with DM in Oslo, Norway, that have the highest prevalence of diabetes mellitus (DM) in the country, using both manual (ophthalmologist) and autonomous (AI) grading. This is the first study in Norway, as far as we know, that uses AI in DR- grading of retinal images.</p><p><strong>Methods: </strong>On Minority Women's Day, November 1, 2017, in Oslo, Norway, 33 patients (66 eyes) over 18 years of age diagnosed with DM (T1D and T2D) were screened. The Eidon - True Color Confocal Scanner (CenterVue, United States) was used for retinal imaging and graded for DR after screening had been completed, by an ophthalmologist and automatically, using EyeArt Automated DR Detection System, version 2.1.0 (EyeArt, EyeNuk, CA, USA). The gradings were based on the International Clinical Diabetic Retinopathy (ICDR) severity scale [1] detecting the presence or absence of referable DR. Cost-minimization analyses were performed for both grading methods.</p><p><strong>Results: </strong>33 women (64 eyes) were eligible for the analysis. A very good inter-rater agreement was found: 0.98 (P < 0.01), between the human and AI-based EyeArt grading system for detecting DR. The prevalence of DR was 18.6% (95% CI: 11.4-25.8%), and the sensitivity and specificity were 100% (95% CI: 100-100% and 95% CI: 100-100%), respectively. The cost difference for AI screening compared to human screening was $143 lower per patient (cost-saving) in favour of AI.</p><p><strong>Conclusion: </strong>Our results indicate that The EyeArt AI system is both a reliable, cost-saving, and useful tool for DR grading in clinical practice.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-21DOI: 10.1186/s40942-024-00556-2
Rami Al-Dwairi, Tamam El-Elimat, Abdelwahab Aleshawi, Ahmed Al Sharie, Seren Al Beiruti, Abdallah K Sharayah, Mohammed Allouh
Background: This study aims to investigate the factors affecting the vitreous levels of pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VGEF) among patients with pars plana vitrectomy (PPV). Also, this study correlates the levels of PEDF with RRD characteristics.
Methods: All patients who were scheduled for PPV for any indication were included in the study. They were divided into a case group which included patients with advanced PDR and a control group which included the remaining diagnoses. During the PPV, an undiluted vitreous sample was taken and the enzyme-linked immunosorbent assay method was utilized to measure the levels of VEGF and PEDF.
Results: Eighty eyes were involved. Patients diagnosed with advanced PDR and endophthalmitis exhibited higher levels of VEGF. PEDF was affected inversely by the age of the patients and PEDF levels were higher in RRD and endophthalmitis cases. In patients with RRD, the level of PEDF was higher if the tear was found inferiorly, if the macula was detached, and with a longer duration of RRD.
Conclusions: This study highlights the clinical importance of those biomarkers. Anti-VEGF-based treatment is the mainstay against PDR. PEDF may show a promising predictive values regarding patients with RRD.
{"title":"Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic and non-diabetic retinopathy: associated factors and anatomical correlation.","authors":"Rami Al-Dwairi, Tamam El-Elimat, Abdelwahab Aleshawi, Ahmed Al Sharie, Seren Al Beiruti, Abdallah K Sharayah, Mohammed Allouh","doi":"10.1186/s40942-024-00556-2","DOIUrl":"10.1186/s40942-024-00556-2","url":null,"abstract":"<p><strong>Background: </strong>This study aims to investigate the factors affecting the vitreous levels of pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VGEF) among patients with pars plana vitrectomy (PPV). Also, this study correlates the levels of PEDF with RRD characteristics.</p><p><strong>Methods: </strong>All patients who were scheduled for PPV for any indication were included in the study. They were divided into a case group which included patients with advanced PDR and a control group which included the remaining diagnoses. During the PPV, an undiluted vitreous sample was taken and the enzyme-linked immunosorbent assay method was utilized to measure the levels of VEGF and PEDF.</p><p><strong>Results: </strong>Eighty eyes were involved. Patients diagnosed with advanced PDR and endophthalmitis exhibited higher levels of VEGF. PEDF was affected inversely by the age of the patients and PEDF levels were higher in RRD and endophthalmitis cases. In patients with RRD, the level of PEDF was higher if the tear was found inferiorly, if the macula was detached, and with a longer duration of RRD.</p><p><strong>Conclusions: </strong>This study highlights the clinical importance of those biomarkers. Anti-VEGF-based treatment is the mainstay against PDR. PEDF may show a promising predictive values regarding patients with RRD.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11106866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141075630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-26DOI: 10.1186/s40942-024-00555-3
Samir Touma, Badr Ait Hammou, Fares Antaki, Marie Carole Boucher, Renaud Duval
Background: Code-free deep learning (CFDL) is a novel tool in artificial intelligence (AI). This study directly compared the discriminative performance of CFDL models designed by ophthalmologists without coding experience against bespoke models designed by AI experts in detecting retinal pathologies from optical coherence tomography (OCT) videos and fovea-centered images.
Methods: Using the same internal dataset of 1,173 OCT macular videos and fovea-centered images, model development was performed simultaneously but independently by an ophthalmology resident (CFDL models) and a postdoctoral researcher with expertise in AI (bespoke models). We designed a multi-class model to categorize video and fovea-centered images into five labels: normal retina, macular hole, epiretinal membrane, wet age-related macular degeneration and diabetic macular edema. We qualitatively compared point estimates of the performance metrics of the CFDL and bespoke models.
Results: For videos, the CFDL model demonstrated excellent discriminative performance, even outperforming the bespoke models for some metrics: area under the precision-recall curve was 0.984 (vs. 0.901), precision and sensitivity were both 94.1% (vs. 94.2%) and accuracy was 94.1% (vs. 96.7%). The fovea-centered CFDL model overall performed better than video-based model and was as accurate as the best bespoke model.
Conclusion: This comparative study demonstrated that code-free models created by clinicians without coding expertise perform as accurately as expert-designed bespoke models at classifying various retinal pathologies from OCT videos and images. CFDL represents a step forward towards the democratization of AI in medicine, although its numerous limitations must be carefully addressed to ensure its effective application in healthcare.
背景:无代码深度学习(CFDL)是人工智能(AI)领域的一种新型工具。本研究直接比较了没有编码经验的眼科医生设计的 CFDL 模型与人工智能专家设计的定制模型在从光学相干断层扫描(OCT)视频和以眼窝为中心的图像中检测视网膜病变方面的判别性能:使用同一内部数据集(1,173 个 OCT 黄斑视频和以眼窝为中心的图像),由一名眼科住院医师(CFDL 模型)和一名具有人工智能专业知识的博士后研究员(定制模型)同时独立进行模型开发。我们设计了一个多类模型,将视频和以眼窝为中心的图像分为五个标签:正常视网膜、黄斑孔、视网膜外膜、湿性年龄相关性黄斑变性和糖尿病性黄斑水肿。我们对 CFDL 模型和定制模型的性能指标点估计值进行了定性比较:在视频方面,CFDL 模型表现出卓越的判别性能,甚至在某些指标上优于定制模型:精确度-召回曲线下面积为 0.984(vs.0.901),精确度和灵敏度均为 94.1%(vs.94.2%),准确度为 94.1%(vs.96.7%)。以眼窝为中心的 CFDL 模型总体表现优于基于视频的模型,其准确性与最佳定制模型相当:这项比较研究表明,在对 OCT 视频和图像中的各种视网膜病变进行分类时,没有编码专业知识的临床医生创建的无编码模型与专家设计的定制模型一样准确。CFDL代表着人工智能在医学领域的民主化向前迈进了一步,但要确保其在医疗保健领域的有效应用,还必须认真解决其诸多局限性。
{"title":"Comparing code-free deep learning models to expert-designed models for detecting retinal diseases from optical coherence tomography.","authors":"Samir Touma, Badr Ait Hammou, Fares Antaki, Marie Carole Boucher, Renaud Duval","doi":"10.1186/s40942-024-00555-3","DOIUrl":"https://doi.org/10.1186/s40942-024-00555-3","url":null,"abstract":"<p><strong>Background: </strong>Code-free deep learning (CFDL) is a novel tool in artificial intelligence (AI). This study directly compared the discriminative performance of CFDL models designed by ophthalmologists without coding experience against bespoke models designed by AI experts in detecting retinal pathologies from optical coherence tomography (OCT) videos and fovea-centered images.</p><p><strong>Methods: </strong>Using the same internal dataset of 1,173 OCT macular videos and fovea-centered images, model development was performed simultaneously but independently by an ophthalmology resident (CFDL models) and a postdoctoral researcher with expertise in AI (bespoke models). We designed a multi-class model to categorize video and fovea-centered images into five labels: normal retina, macular hole, epiretinal membrane, wet age-related macular degeneration and diabetic macular edema. We qualitatively compared point estimates of the performance metrics of the CFDL and bespoke models.</p><p><strong>Results: </strong>For videos, the CFDL model demonstrated excellent discriminative performance, even outperforming the bespoke models for some metrics: area under the precision-recall curve was 0.984 (vs. 0.901), precision and sensitivity were both 94.1% (vs. 94.2%) and accuracy was 94.1% (vs. 96.7%). The fovea-centered CFDL model overall performed better than video-based model and was as accurate as the best bespoke model.</p><p><strong>Conclusion: </strong>This comparative study demonstrated that code-free models created by clinicians without coding expertise perform as accurately as expert-designed bespoke models at classifying various retinal pathologies from OCT videos and images. CFDL represents a step forward towards the democratization of AI in medicine, although its numerous limitations must be carefully addressed to ensure its effective application in healthcare.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11055378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140850557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-23DOI: 10.1186/s40942-024-00554-4
Matthew Driban, Audrey Yan, A. Selvam, J. Ong, K. Vupparaboina, Jay Chhablani
{"title":"Artificial intelligence in chorioretinal pathology through fundoscopy: a comprehensive review","authors":"Matthew Driban, Audrey Yan, A. Selvam, J. Ong, K. Vupparaboina, Jay Chhablani","doi":"10.1186/s40942-024-00554-4","DOIUrl":"https://doi.org/10.1186/s40942-024-00554-4","url":null,"abstract":"","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140671107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-23DOI: 10.1186/s40942-024-00552-6
Miguel A. Quiroz-Reyes, Zaheer-Ud-Din Babar, R. Hussain, Zhe Chi Loh, E. Quiroz-Gonzalez, M. A. Quiroz-Gonzalez, V. Lima-Gómez
{"title":"Management, risk factors and treatment outcomes of rhegmatogenous retinal detachment associated with giant retinal tears: scoping review","authors":"Miguel A. Quiroz-Reyes, Zaheer-Ud-Din Babar, R. Hussain, Zhe Chi Loh, E. Quiroz-Gonzalez, M. A. Quiroz-Gonzalez, V. Lima-Gómez","doi":"10.1186/s40942-024-00552-6","DOIUrl":"https://doi.org/10.1186/s40942-024-00552-6","url":null,"abstract":"","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140669784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-16DOI: 10.1186/s40942-024-00551-7
Matheus Senna Pereira Ogata, Guilherme Rodrigues Ferreira, M. Morales, Arthur Gustavo Fernandes
{"title":"Ocular metastases profile in a tertiary hospital in São Paulo, Brazil","authors":"Matheus Senna Pereira Ogata, Guilherme Rodrigues Ferreira, M. Morales, Arthur Gustavo Fernandes","doi":"10.1186/s40942-024-00551-7","DOIUrl":"https://doi.org/10.1186/s40942-024-00551-7","url":null,"abstract":"","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140695495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-11DOI: 10.1186/s40942-024-00548-2
Ramon Antunes De Oliveira, Vinicius Oliveira Pesquero, Lucas Zago Ribeiro, M. Polizelli, Aalec Rinhel Souza Ferreira Da Silva, Nilva Simeren Bueno De Moraes, Rodrigo Antonio Brant Fernandes, O. Júnior, Mauricio Maia
{"title":"Retrospective case series of high-density silicone oil (Oxane HD) in severe proliferative vitreorretinal retinal detachment patients","authors":"Ramon Antunes De Oliveira, Vinicius Oliveira Pesquero, Lucas Zago Ribeiro, M. Polizelli, Aalec Rinhel Souza Ferreira Da Silva, Nilva Simeren Bueno De Moraes, Rodrigo Antonio Brant Fernandes, O. Júnior, Mauricio Maia","doi":"10.1186/s40942-024-00548-2","DOIUrl":"https://doi.org/10.1186/s40942-024-00548-2","url":null,"abstract":"","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140715164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-08DOI: 10.1186/s40942-024-00549-1
Virginia Mares, M. Nehemy, H. Bogunović, Sophie Frank, G. Reiter, U. Schmidt-Erfurth
{"title":"AI-based support for optical coherence tomography in age-related macular degeneration","authors":"Virginia Mares, M. Nehemy, H. Bogunović, Sophie Frank, G. Reiter, U. Schmidt-Erfurth","doi":"10.1186/s40942-024-00549-1","DOIUrl":"https://doi.org/10.1186/s40942-024-00549-1","url":null,"abstract":"","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140729672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-08DOI: 10.1186/s40942-024-00553-5
Ryoh Funatsu, Hiroto Terasaki, Naohisa Mihara, S. Sonoda, Hideki Shiihara, T. Sakamoto
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