首页 > 最新文献

International Journal of Otorhinolaryngology and Head and Neck Surgery最新文献

英文 中文
Study of the empirical role of proton pump inhibitor therapy on laryngopharyngeal reflux 质子泵抑制剂疗法对喉咽反流的经验作用研究
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233578
N. Chhabra, Ankita Aggarwal, Sanjeev Bhagat, Khushboo Goel
Background: Laryngopharyngeal reflux (LPR) is a highly prevalent disease and commonly encountered in the otolaryngologist’s office. Study to evaluate the presentation of different signs and symptoms of LPR along with evaluating the role of empiric PPI (proton pump inhibitor) in the management of LPR by observing its effect on RFS and RSI. Methods: A prospective observational study was conducted on 100 cases having different symptoms of LPR. Reflux symptom index (RSI) and Reflux finding score (RFS) were used to diagnose LPR. Patients were put on PPI (Pantoprazole 40 mg OD for 12 weeks) and followed up at 4,8 and 12 weeks and successive RSI and RFS scores were evaluated. The results were compiled and analyzed statistically. Results: Among all symptoms, most common presenting symptom of LPR was foreign body/sensation of something sticking in throat (80%). Upon pharmacological therapy with PPIs (Pantoprazole), the mean RSI score changed from 22.94±5.83 to 11.19±2.97 at 12 weeks of PPI therapy. The mean RFS score changed from 12.93±3.55 to 6.86±2.86 at 12 weeks of PPI therapy. The change in the RFS and RSI score was highly significant (p=0.001). Conclusions: LPR is a common condition presenting in ENT settings, the symptoms and signs of which may be complex. RFS and RSI score are valuable tools for diagnosing LPR. PPIs are proven to be effective therapy for LPR, more studies are encouraged to affirm the efficacy of PPIs over other management options.
背景:喉咽反流(LPR)是一种高发疾病,在耳鼻喉科医生的诊室中经常会遇到。本研究旨在评估 LPR 不同体征和症状的表现,并通过观察经验性 PPI(质子泵抑制剂)对 RFS 和 RSI 的影响,评估其在 LPR 治疗中的作用。研究方法对 100 例具有不同症状的 LPR 病例进行了前瞻性观察研究。反流症状指数(RSI)和反流发现评分(RFS)用于诊断 LPR。患者服用 PPI(泮托拉唑 40 毫克,口服,12 周),并在 4、8 和 12 周时进行随访,评估连续的 RSI 和 RFS 评分。对结果进行汇总和统计分析。结果在所有症状中,LPR 最常见的症状是咽喉异物感(80%)。使用 PPIs(泮托拉唑)进行药物治疗后,在 PPI 治疗 12 周时,RSI 平均得分从 22.94±5.83 降至 11.19±2.97。PPI 治疗 12 周后,平均 RFS 评分从(12.93±3.55)分变为(6.86±2.86)分。RFS和RSI评分的变化非常显著(P=0.001)。结论LPR 是耳鼻喉科常见疾病,其症状和体征可能很复杂。RFS 和 RSI 评分是诊断 LPR 的重要工具。事实证明,PPIs 是治疗 LPR 的有效药物,我们鼓励开展更多研究,以确认 PPIs 相对于其他治疗方案的疗效。
{"title":"Study of the empirical role of proton pump inhibitor therapy on laryngopharyngeal reflux","authors":"N. Chhabra, Ankita Aggarwal, Sanjeev Bhagat, Khushboo Goel","doi":"10.18203/issn.2454-5929.ijohns20233578","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233578","url":null,"abstract":"Background: Laryngopharyngeal reflux (LPR) is a highly prevalent disease and commonly encountered in the otolaryngologist’s office. Study to evaluate the presentation of different signs and symptoms of LPR along with evaluating the role of empiric PPI (proton pump inhibitor) in the management of LPR by observing its effect on RFS and RSI. Methods: A prospective observational study was conducted on 100 cases having different symptoms of LPR. Reflux symptom index (RSI) and Reflux finding score (RFS) were used to diagnose LPR. Patients were put on PPI (Pantoprazole 40 mg OD for 12 weeks) and followed up at 4,8 and 12 weeks and successive RSI and RFS scores were evaluated. The results were compiled and analyzed statistically. Results: Among all symptoms, most common presenting symptom of LPR was foreign body/sensation of something sticking in throat (80%). Upon pharmacological therapy with PPIs (Pantoprazole), the mean RSI score changed from 22.94±5.83 to 11.19±2.97 at 12 weeks of PPI therapy. The mean RFS score changed from 12.93±3.55 to 6.86±2.86 at 12 weeks of PPI therapy. The change in the RFS and RSI score was highly significant (p=0.001). Conclusions: LPR is a common condition presenting in ENT settings, the symptoms and signs of which may be complex. RFS and RSI score are valuable tools for diagnosing LPR. PPIs are proven to be effective therapy for LPR, more studies are encouraged to affirm the efficacy of PPIs over other management options.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139229111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual neck masses encountered in remote areas of Sikkim 锡金偏远地区遇到的异常颈部肿块
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233582
Santosh Kesari, Priyanko Chakraborty, Aseem Anand, Subhasish Mukherjee
Neck masses are one of the most common presentations in the ENT practice and they are a challenge in the diagnosis and management. The masses may be of congenital, inflammatory, or neoplastic origin. An accurate clinical assessment conducted while taking into account pertinent anatomical and developmental viewpoints, accompanied by well-planned investigative parameters, may aid in making an early diagnosis. Our is a series of three cases where in which we have described the finding of all the three cases in detail, first case is of 70 years female with right sided neck swelling which ultimately turned out to be right venous aneurysm. Second being a case of a young kid misdiagnosed as other infections and treated for long time, which ultimately responded with ATT. Lastly, a young kid presenting with multinodular goitre. We need to be ready for surprise and be ready to deal with unusual cases with different management options.
颈部肿块是耳鼻喉科最常见的病症之一,也是诊断和治疗的难题。肿块可能是先天性的,也可能是炎症性或肿瘤性的。在进行准确的临床评估的同时,考虑到相关的解剖和发育观点,并辅以精心策划的检查参数,可能有助于早期诊断。第一个病例是一名 70 岁女性,右侧颈部肿胀,最终被证实为右侧静脉瘤。第二个病例是一名被误诊为其他感染并接受了长期治疗的年轻儿童,最终在 ATT 治疗后好转。最后一个病例是一名患有多结节性甲状腺肿的年轻儿童。我们需要做好应对突发情况的准备,并随时准备以不同的治疗方案处理不寻常的病例。
{"title":"Unusual neck masses encountered in remote areas of Sikkim","authors":"Santosh Kesari, Priyanko Chakraborty, Aseem Anand, Subhasish Mukherjee","doi":"10.18203/issn.2454-5929.ijohns20233582","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233582","url":null,"abstract":"Neck masses are one of the most common presentations in the ENT practice and they are a challenge in the diagnosis and management. The masses may be of congenital, inflammatory, or neoplastic origin. An accurate clinical assessment conducted while taking into account pertinent anatomical and developmental viewpoints, accompanied by well-planned investigative parameters, may aid in making an early diagnosis. Our is a series of three cases where in which we have described the finding of all the three cases in detail, first case is of 70 years female with right sided neck swelling which ultimately turned out to be right venous aneurysm. Second being a case of a young kid misdiagnosed as other infections and treated for long time, which ultimately responded with ATT. Lastly, a young kid presenting with multinodular goitre. We need to be ready for surprise and be ready to deal with unusual cases with different management options.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amelanotic mucosal melanoma of the left sinonasal cavity: a case report 左鼻窦粘膜黑色素瘤:病例报告
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233583
Yonanda Adi Pratama, I. K. Praba, C. Herdini, S. R. Indrasari, Danu Yudistira, Yosephine Nina
Mucosal melanoma is rare type of melanoma accounted only 0.8-3.7% of melanoma. It defined as melanoma which occurs in mucous membrane, oral and nasal cavities, conjunctiva, genital sites, and rarely other mucosae. Head and neck melanoma accounted 50% among other sites. Recent studies, amelanotic subtype account 13.2% of all sino-nasal melanoma. Nasal cavity melanoma usually occurs on lateral nasal area especially in middle turbinate and inferior turbinate. Among other location, sino-nasal originated primary lesion was more deadly compared to other. We reported a case of amelanotic melanoma. 56 years old Asian Female presented with mass in left nose. The patient also complaint of recurring epistaxis, facial pain, epiphora, and blurred vision. After several follow up investigation, a diagnosis of amelanotic melanoma with orbit involvement was made. Subsequently patient underwent surgery for tumor removal. Although tumor has been removed, patient had to continue with adjuvant therapy for following month. Meticulous identifying and confirmation is an important factor which provide better understanding for the clinician in diagnosing.
粘膜黑色素瘤是一种罕见的黑色素瘤,仅占黑色素瘤的 0.8-3.7%。它是指发生在粘膜、口腔和鼻腔、结膜、生殖器部位的黑色素瘤,很少发生在其他粘膜。头颈部黑色素瘤占其他部位黑色素瘤的 50%。最近的研究表明,在所有鼻腔黑色素瘤中,黑色素亚型占 13.2%。鼻腔黑色素瘤通常发生在鼻腔外侧,尤其是中鼻甲和下鼻甲。与其他部位的黑色素瘤相比,鼻腔黑色素瘤的原发病灶更为致命。我们报告了一例黑色素瘤病例。56 岁亚洲女性,左鼻肿块。患者还主诉反复鼻衄、面部疼痛、眼花和视力模糊。经过多次随访检查,确诊为累及眼眶的黑色素瘤。随后,患者接受了肿瘤切除手术。虽然肿瘤已被切除,但患者仍需继续接受一个月的辅助治疗。缜密的鉴别和确认是一个重要因素,它能让临床医生更好地理解诊断。
{"title":"Amelanotic mucosal melanoma of the left sinonasal cavity: a case report","authors":"Yonanda Adi Pratama, I. K. Praba, C. Herdini, S. R. Indrasari, Danu Yudistira, Yosephine Nina","doi":"10.18203/issn.2454-5929.ijohns20233583","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233583","url":null,"abstract":"Mucosal melanoma is rare type of melanoma accounted only 0.8-3.7% of melanoma. It defined as melanoma which occurs in mucous membrane, oral and nasal cavities, conjunctiva, genital sites, and rarely other mucosae. Head and neck melanoma accounted 50% among other sites. Recent studies, amelanotic subtype account 13.2% of all sino-nasal melanoma. Nasal cavity melanoma usually occurs on lateral nasal area especially in middle turbinate and inferior turbinate. Among other location, sino-nasal originated primary lesion was more deadly compared to other. We reported a case of amelanotic melanoma. 56 years old Asian Female presented with mass in left nose. The patient also complaint of recurring epistaxis, facial pain, epiphora, and blurred vision. After several follow up investigation, a diagnosis of amelanotic melanoma with orbit involvement was made. Subsequently patient underwent surgery for tumor removal. Although tumor has been removed, patient had to continue with adjuvant therapy for following month. Meticulous identifying and confirmation is an important factor which provide better understanding for the clinician in diagnosing.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139233979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Middle ear neuroendocrine tumour-case report of a rare tumour of the temporal bone 中耳神经内分泌肿瘤--颞骨罕见肿瘤的病例报告
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233589
Manali Bhat, H. Vijayendra, V. Vijayendra, Nilesh H Mahajan
Several conditions are known to present as masses in the middle ear medial to an intact tympanic membrane. Reddish masses that blanch on seigelization are usually paragangliomas. Sometimes, a high rising jugular bulb or an aberrant carotid artery can also be seen. Whitish masses are usually congenital cholesteatomas, tympanosclerosis, cartilage grafts that have been surgically placed, and rarely middle ear adenomas (MEA).  An elderly male presented with decreased hearing, which was revealed to be secondary to a pale mass in the middle ear, displacing the intact tympanic membrane laterally. He underwent biopsy followed by complete excision of the mass, with preservation of the intact ossicular chain. There no evidence of recurrence on follow-up. Histopathology revealed the mass to be a MEA, also known as middle ear neuroendocrine tumour (MeNET). Middle ear neuroendocrine tumours are rare tumours. We describe the clinical presentation and management of this tumour.
已知有几种疾病会在完整鼓膜内侧的中耳出现肿块。呈淡红色的肿块在硬结时会发蓝,通常是副神经节瘤。有时也可见到颈静脉球高耸或颈动脉异常。白色肿块通常是先天性胆脂瘤、鼓室硬化症、手术放置的软骨移植,很少见的是中耳腺瘤(MEA)。 一名老年男性出现听力下降,经检查发现是中耳苍白肿块引起的,肿块使完整的鼓膜向侧方移位。他接受了活组织检查,随后完全切除了肿块,保留了完整的听骨链。随访未发现复发迹象。组织病理学检查显示,肿块为中耳神经内分泌肿瘤(MEA),又称中耳神经内分泌肿瘤(MeNET)。中耳神经内分泌肿瘤是一种罕见肿瘤。我们将介绍这种肿瘤的临床表现和治疗方法。
{"title":"Middle ear neuroendocrine tumour-case report of a rare tumour of the temporal bone","authors":"Manali Bhat, H. Vijayendra, V. Vijayendra, Nilesh H Mahajan","doi":"10.18203/issn.2454-5929.ijohns20233589","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233589","url":null,"abstract":"Several conditions are known to present as masses in the middle ear medial to an intact tympanic membrane. Reddish masses that blanch on seigelization are usually paragangliomas. Sometimes, a high rising jugular bulb or an aberrant carotid artery can also be seen. Whitish masses are usually congenital cholesteatomas, tympanosclerosis, cartilage grafts that have been surgically placed, and rarely middle ear adenomas (MEA).  An elderly male presented with decreased hearing, which was revealed to be secondary to a pale mass in the middle ear, displacing the intact tympanic membrane laterally. He underwent biopsy followed by complete excision of the mass, with preservation of the intact ossicular chain. There no evidence of recurrence on follow-up. Histopathology revealed the mass to be a MEA, also known as middle ear neuroendocrine tumour (MeNET). Middle ear neuroendocrine tumours are rare tumours. We describe the clinical presentation and management of this tumour.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical outcome of type I tympanoplasty in different types of mucosal chronic otitis media: a prospective study 不同类型粘膜慢性中耳炎的 I 型鼓室成形术手术效果:一项前瞻性研究
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233579
V. Harkare, Shiwani S. Pidurakar, S. Khadakkar, Nitin V. Deosthale, Priti R. Dhoke, Kanchan S. Dhote
Background: Chronic otitis media (COM) is a long-standing infection of middle ear cleft, causes severe destruction and leading to irreversible sequelae. The interval to convert discharging ear into dry is variable. Extensive counselling is required to keep these patients motivated for prolonged treatment duration. Hence, the study was conducted. Methods: A prospective study was carried out at NKP Salve and Lata Mangeshkar Hospital Nagpur, Maharashtra, between the age group of 16-60 years, who underwent type 1 tympanoplasty. Results were statistically analysed with respect to graft uptake, hearing improvement and size of perforation over a period of 2 years. Temporalis fascia was taken as a graft material. Results: Out of 70 cases, 38 cases had inactive ears and 32 cases had minimal, mucoid ear discharge (Active ear), which bacteriologically showed no organism. M:F ratio was 1.12:1. Graft uptake was successful in 92.11% of the cases in inactive group and 93.75% of the cases in active group. Graft uptake was 100% in small and moderate perforation. Hearing improvement was achieved in 71.05% of cases in the inactive group and 78.12% of cases in the active group, as measured by closure of the air-bone gap (ABG) and improvement in conductive hearing (significant >10 dB). We found no difference in the success rates. Conclusions: Presence of minimal discharge will not affect the surgical outcome of type 1 tympanoplasty in terms of graft uptake, hearing improvement and size of perforation.
背景:慢性中耳炎(COM)是一种长期存在的中耳裂感染,会造成严重破坏并导致不可逆转的后遗症。将流脓耳转为干耳的时间间隔不定。需要对这些患者进行广泛的辅导,使其保持长期治疗的积极性。因此,我们开展了这项研究。研究方法在马哈拉施特拉邦那格浦尔的 NKP Salve 和 Lata Mangeshkar 医院开展了一项前瞻性研究,研究对象为年龄在 16-60 岁之间、接受过 1 型鼓室成形术的患者。对结果进行了统计分析,包括移植物吸收、听力改善和两年内穿孔的大小。移植材料为颞筋膜。结果在 70 个病例中,38 个病例的耳朵没有活动,32 个病例的耳朵有少量粘液性分泌物(活动耳),细菌学检查未发现病原体。中耳与外耳的比例为 1.12:1。92.11% 的非活动耳移植成功,93.75% 的活动耳移植成功。小穿孔和中度穿孔的移植物吸收率为 100%。根据气骨间隙(ABG)的闭合情况和传导听力的改善情况(显著>10 dB),71.05% 的非活动组病例和 78.12% 的活动组病例的听力得到了改善。我们在成功率方面没有发现差异。结论就移植物吸收、听力改善和穿孔大小而言,存在少量分泌物不会影响 1 型鼓室成形术的手术效果。
{"title":"Surgical outcome of type I tympanoplasty in different types of mucosal chronic otitis media: a prospective study","authors":"V. Harkare, Shiwani S. Pidurakar, S. Khadakkar, Nitin V. Deosthale, Priti R. Dhoke, Kanchan S. Dhote","doi":"10.18203/issn.2454-5929.ijohns20233579","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233579","url":null,"abstract":"Background: Chronic otitis media (COM) is a long-standing infection of middle ear cleft, causes severe destruction and leading to irreversible sequelae. The interval to convert discharging ear into dry is variable. Extensive counselling is required to keep these patients motivated for prolonged treatment duration. Hence, the study was conducted. Methods: A prospective study was carried out at NKP Salve and Lata Mangeshkar Hospital Nagpur, Maharashtra, between the age group of 16-60 years, who underwent type 1 tympanoplasty. Results were statistically analysed with respect to graft uptake, hearing improvement and size of perforation over a period of 2 years. Temporalis fascia was taken as a graft material. Results: Out of 70 cases, 38 cases had inactive ears and 32 cases had minimal, mucoid ear discharge (Active ear), which bacteriologically showed no organism. M:F ratio was 1.12:1. Graft uptake was successful in 92.11% of the cases in inactive group and 93.75% of the cases in active group. Graft uptake was 100% in small and moderate perforation. Hearing improvement was achieved in 71.05% of cases in the inactive group and 78.12% of cases in the active group, as measured by closure of the air-bone gap (ABG) and improvement in conductive hearing (significant >10 dB). We found no difference in the success rates. Conclusions: Presence of minimal discharge will not affect the surgical outcome of type 1 tympanoplasty in terms of graft uptake, hearing improvement and size of perforation.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual presentations of branchial cyst 腮腺囊肿的不寻常表现
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233581
Priti S. Hajare, Vinita V. Metgudmath, Izhak Mehadi, Neema K., Elsa Babu, Dhanush Nayak
Branchial cyst is a developmental cyst commonly presenting as a solitary, painless neck mass, typically located over lateral aspect of the neck. Most commonly located along the anterior border and the upper third of the sternocleidomastoid muscle in the anterior triangle of the neck, it is very rare for a branchial cyst to manifest in other locations. Branchial cysts are believed to be derived from the branchial apparatus, mostly from the second branchial arch, although many theories have been proposed to explain the aetiology of branchial cysts. Congenital branchial cysts of the nasopharynx originate from the lateral nasopharynx with an inferior and medial extension. This rare and unusual occurrence of the cyst is characterised by its avid mucus secretion and unilateral presentation. Here we present four different presentations of branchial cyst - as a midline swelling, an unusually large presentation, nasopharyngeal presentation. Histopathology report showed cyst lined by stratified squamous epithelium and pseudo stratified ciliated columnar epithelium at places along with subepithelial lymphocytes suggesting branchial cyst. Hence, Branchial cyst should also be taken as one of the differential diagnoses in cystic lesions of the neck and lateral cystic lesions of nasopharynx.
腮腺囊肿是一种发育性囊肿,通常表现为单发、无痛的颈部肿块,一般位于颈部外侧。腮腺囊肿最常位于颈部前三角区的前缘和胸锁乳突肌的上三分之一处,在其他部位表现为腮腺囊肿的情况非常罕见。腮腺囊肿被认为源于腮腺器械,主要来自第二腮弓,尽管有许多理论可以解释腮腺囊肿的病因。先天性鼻咽支气管囊肿起源于鼻咽外侧,并向下和内侧延伸。这种罕见的鼻咽支气管囊肿具有粘液分泌旺盛和单侧发病的特点。在这里,我们介绍了腮腺囊肿的四种不同表现形式--中线肿物、异常巨大的表现、鼻咽部表现。组织病理报告显示,囊肿内有分层鳞状上皮和假分层纤毛柱状上皮,上皮下有淋巴细胞,提示为腮腺囊肿。因此,腮腺囊肿也应作为颈部囊性病变和鼻咽侧囊性病变的鉴别诊断之一。
{"title":"Unusual presentations of branchial cyst","authors":"Priti S. Hajare, Vinita V. Metgudmath, Izhak Mehadi, Neema K., Elsa Babu, Dhanush Nayak","doi":"10.18203/issn.2454-5929.ijohns20233581","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233581","url":null,"abstract":"Branchial cyst is a developmental cyst commonly presenting as a solitary, painless neck mass, typically located over lateral aspect of the neck. Most commonly located along the anterior border and the upper third of the sternocleidomastoid muscle in the anterior triangle of the neck, it is very rare for a branchial cyst to manifest in other locations. Branchial cysts are believed to be derived from the branchial apparatus, mostly from the second branchial arch, although many theories have been proposed to explain the aetiology of branchial cysts. Congenital branchial cysts of the nasopharynx originate from the lateral nasopharynx with an inferior and medial extension. This rare and unusual occurrence of the cyst is characterised by its avid mucus secretion and unilateral presentation. Here we present four different presentations of branchial cyst - as a midline swelling, an unusually large presentation, nasopharyngeal presentation. Histopathology report showed cyst lined by stratified squamous epithelium and pseudo stratified ciliated columnar epithelium at places along with subepithelial lymphocytes suggesting branchial cyst. Hence, Branchial cyst should also be taken as one of the differential diagnoses in cystic lesions of the neck and lateral cystic lesions of nasopharynx.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139234014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe esophageal candidiasis in a megaesophagus patient: a rare case 巨型食管患者的严重食管念珠菌病:一个罕见病例
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233588
Solikin, Muhammad A. Darmawan, Monik Alamanda, Agus Surono
Megaesophagus is a largely dilated esophagus, an uncommon condition that could be the end-stage of preceding esophageal achalasia. Chronic food stasis such as in achalasia and megaesophagus could cause fungi infection in the esophagus. This report aimed to raise awareness of these rare cases. A 68-year-old male with two decades of swallowing difficulty was referred to Sardjito Hospital. Computed tomography esophagography showed megaesophagus and bird beak sign suggesting achalasia. Both esophagoscopy and esophageal tissue biopsy showed consistent results of severe esophageal candidiasis (EC). The patient was also suspected to have a mass at the distal part of the esophagus and gastric cardia, which could also contribute to the esophageal obstruction. We consulted the gastroenterologist for gastrostomy feeding and exploration of the suspected tumor. EC is known mainly in patients with immunodeficiency, while food stasis is a lesser-known cause. End-stage achalasia not only could lead to megaesophagus, but chronic food stasis is the perfect environment for fungi growth. Other causes of food stasis such as distal esophageal and gastric cardia tumors could also be the predisposition of EC. We reported a rare case of a patient with EC as a complication of megaesophagus and esophageal achalasia.
巨型食管是指食管大部分扩张,这种情况并不常见,可能是食管贲门失弛缓症的终末阶段。贲门失弛缓症和巨型食管等慢性食物淤积症可能导致食管真菌感染。本报告旨在提高人们对这些罕见病例的认识。一名 68 岁的男性被转诊到 Sardjito 医院,他有二十年的吞咽困难。计算机断层扫描食管造影显示他患有巨型食管和鸟嘴征,提示他患有贲门失弛缓症。食管镜检查和食管组织活检结果一致,显示患者患有严重的食管念珠菌病(EC)。我们还怀疑患者的食管远端和胃贲门处有肿块,这也可能导致食管梗阻。我们咨询了消化科医生,要求进行胃造口术,并对疑似肿瘤进行探查。众所周知,食管梗阻主要发生在免疫缺陷患者身上,而食物淤积则是一个鲜为人知的原因。终末期贲门失弛缓症不仅会导致巨型食管,而且长期的食物淤积是真菌生长的绝佳环境。食物淤积的其他原因,如食管远端和胃贲门肿瘤,也可能是导致食管癌的诱因。我们报告了一例罕见的食道癌患者,他是巨食管和食道贲门失弛缓症的并发症。
{"title":"Severe esophageal candidiasis in a megaesophagus patient: a rare case","authors":"Solikin, Muhammad A. Darmawan, Monik Alamanda, Agus Surono","doi":"10.18203/issn.2454-5929.ijohns20233588","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233588","url":null,"abstract":"Megaesophagus is a largely dilated esophagus, an uncommon condition that could be the end-stage of preceding esophageal achalasia. Chronic food stasis such as in achalasia and megaesophagus could cause fungi infection in the esophagus. This report aimed to raise awareness of these rare cases. A 68-year-old male with two decades of swallowing difficulty was referred to Sardjito Hospital. Computed tomography esophagography showed megaesophagus and bird beak sign suggesting achalasia. Both esophagoscopy and esophageal tissue biopsy showed consistent results of severe esophageal candidiasis (EC). The patient was also suspected to have a mass at the distal part of the esophagus and gastric cardia, which could also contribute to the esophageal obstruction. We consulted the gastroenterologist for gastrostomy feeding and exploration of the suspected tumor. EC is known mainly in patients with immunodeficiency, while food stasis is a lesser-known cause. End-stage achalasia not only could lead to megaesophagus, but chronic food stasis is the perfect environment for fungi growth. Other causes of food stasis such as distal esophageal and gastric cardia tumors could also be the predisposition of EC. We reported a rare case of a patient with EC as a complication of megaesophagus and esophageal achalasia.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-grade myofibroblastic sarcoma of the head and neck region: a report of two cases of this extremely rare type of sarcoma and review of literature 头颈部低级别肌纤维肉瘤:两例极为罕见的肉瘤病例报告及文献综述
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233587
S. Jonnalagadda, M. A. A. Khan, Kiranmayee Buddhavarapu, Prateek Raj Betham
Sarcoma of the head and neck are rare and account of less than 1% of all tumors in head and neck region. Low grade myofibroblastic sarcomas (LGMFS) are even rare with only handful of cases ever reported in head and neck. We review 2 cases with LGMFS of maxilla and mandible. Retrospectively reviewed 2 patients who carried histological diagnosis of LGFMS. Previous clinic, operative and referral notes were reviewed along with histopathology slides and radiological studies. A 37-year-old female presented with recurrent right maxillary sinusitis and on CT scan was found to have an expanding mass in right maxillary sinusitis. Biopsy revealed it to be a LGMFS. She underwent total maxillectomy with orbital floor reconstruction, post operative radiation and is disease free for 18 months. A 49-year-old female presented with radiolucent mass on routine radiological examination. Initial enucleation and biopsy revealed it to be a LGMFS and was later treated with segmental mandibulectomy and fibular free graft reconstruction and post-operative radiotherapy.  LGMFS of the bone is extremely rare tumor with only 8 cases being reported earlier from the skeletal system in entire body. Most common mode of presentation is asymptomatic mass found incidentally. These tumors are malignant with a rare propensity to metastasize distally. Hence prompt and accurate histological diagnosis followed by wide surgical excision with adjuvant therapy form important tenets of management.
头颈部肉瘤非常罕见,仅占头颈部所有肿瘤的不到 1%。低级别肌纤维肉瘤(LGMFS)更是罕见,头颈部仅有极少数病例报道。我们回顾了2例上颌骨和下颌骨低级别肌纤维肉瘤患者。回顾性分析了2例组织学诊断为LGFMS的患者。我们回顾了之前的门诊、手术和转诊记录,以及组织病理学切片和放射学研究。一名 37 岁的女性因反复发作的右上颌窦炎就诊,CT 扫描发现她的右上颌窦有一个不断扩大的肿块。活检显示其为 LGMFS。她接受了全上颌骨切除术,并进行了眶底重建,术后接受了放射治疗,18 个月来未再发病。一名 49 岁的女性在常规放射检查中发现放射性肿块。最初的去核和活组织检查发现这是一个 LGMFS,随后接受了下颌骨节段切除术和腓骨游离移植重建术,并在术后接受了放疗。 骨骼中的 LGMFS 是一种极其罕见的肿瘤,早先仅有 8 例报告来自全身骨骼系统。最常见的发病方式是偶然发现无症状肿块。这些肿瘤是恶性的,很少发生远端转移。因此,及时和准确的组织学诊断以及广泛的手术切除和辅助治疗是治疗的重要原则。
{"title":"Low-grade myofibroblastic sarcoma of the head and neck region: a report of two cases of this extremely rare type of sarcoma and review of literature","authors":"S. Jonnalagadda, M. A. A. Khan, Kiranmayee Buddhavarapu, Prateek Raj Betham","doi":"10.18203/issn.2454-5929.ijohns20233587","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233587","url":null,"abstract":"Sarcoma of the head and neck are rare and account of less than 1% of all tumors in head and neck region. Low grade myofibroblastic sarcomas (LGMFS) are even rare with only handful of cases ever reported in head and neck. We review 2 cases with LGMFS of maxilla and mandible. Retrospectively reviewed 2 patients who carried histological diagnosis of LGFMS. Previous clinic, operative and referral notes were reviewed along with histopathology slides and radiological studies. A 37-year-old female presented with recurrent right maxillary sinusitis and on CT scan was found to have an expanding mass in right maxillary sinusitis. Biopsy revealed it to be a LGMFS. She underwent total maxillectomy with orbital floor reconstruction, post operative radiation and is disease free for 18 months. A 49-year-old female presented with radiolucent mass on routine radiological examination. Initial enucleation and biopsy revealed it to be a LGMFS and was later treated with segmental mandibulectomy and fibular free graft reconstruction and post-operative radiotherapy.  LGMFS of the bone is extremely rare tumor with only 8 cases being reported earlier from the skeletal system in entire body. Most common mode of presentation is asymptomatic mass found incidentally. These tumors are malignant with a rare propensity to metastasize distally. Hence prompt and accurate histological diagnosis followed by wide surgical excision with adjuvant therapy form important tenets of management.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139231127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of anatomical and functional results of butterfly myringoplasty versus temporalis fascia underlay myringoplasty 蝶形耳廓成形术与颞筋膜下耳廓成形术的解剖和功能效果比较研究
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233577
S. S., J. Chavadaki
Background: Myringoplasty is traditionally been done by using temporalis fascia graft material. But in recent years understanding of physiology and pathology of middle ear cleft is drastically improved with technical advancement in surgical methods. Various grafts have been tried for myringoplasty time to time with varying results. Methods: A case control study was conducted; where 52 patients underwent myringoplasty with butterfly graft and second group of 52 patients underwent myringoplasty with temporalis fascia graft under general anesthesia in major OT. All the patients were followed up for 3 months. The results of the procedure were assessed, with respect to closure of tympanic membrane perforations and improvement in the air bone gap post operatively. Results: Butterfly group had statistically significant number of healed patients and hearing improvement compared to temporalis fascia group at the end of one month and with no statistical significance at the end of three months. The age group less than 18 years showed better uptake with butterfly graft. The difference of mean pre-operative, 1 month and 3 months post-operative air bone gaps in butterfly graft were 35.57±2.87 dB, 27.86±2.53 dB, 24.65±2.66dB and in temporalis fascia were 35.97±2.6dB, 29.36±1.54dB, 25.12±1.73 dB respectively. Conclusions: Butterfly group had statistically significant hearing improvement in patients compared to temporalis fascia group at one month and with no statistical significance at three months post procedure. The age group less than 18 years showed better uptake with butterfly graft.
背景介绍耳廓成形术传统上使用颞筋膜移植材料。但近年来,随着手术方法技术的进步,人们对中耳裂的生理和病理有了更深入的了解。各种移植材料在耳廓成形术中不断被尝试,但效果不一。方法:进行了一项病例对照研究,其中 52 名患者接受了蝶形移植的耳廓成形术,第二组 52 名患者在大手术室全身麻醉下接受了颞筋膜移植的耳廓成形术。所有患者均接受了 3 个月的随访。对手术效果进行评估,包括鼓膜穿孔的闭合情况以及术后气骨间隙的改善情况。结果:与颞筋膜组相比,蝶骨组在一个月后痊愈的患者人数和听力改善情况有统计学意义,而在三个月后则无统计学意义。年龄小于 18 岁的患者接受蝶形移植的效果更好。蝶形移植术前、术后 1 个月和 3 个月的平均气骨间隙分别为(35.57±2.87)dB、(27.86±2.53)dB、(24.65±2.66)dB,而颞筋膜移植术前、术后 1 个月和 3 个月的平均气骨间隙分别为(35.97±2.6)dB、(29.36±1.54)dB、(25.12±1.73)dB。结论与颞筋膜组相比,蝶骨组患者术后一个月的听力改善有统计学意义,术后三个月的听力改善无统计学意义。年龄小于 18 岁的患者接受蝶形移植的效果更好。
{"title":"Comparative study of anatomical and functional results of butterfly myringoplasty versus temporalis fascia underlay myringoplasty","authors":"S. S., J. Chavadaki","doi":"10.18203/issn.2454-5929.ijohns20233577","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233577","url":null,"abstract":"Background: Myringoplasty is traditionally been done by using temporalis fascia graft material. But in recent years understanding of physiology and pathology of middle ear cleft is drastically improved with technical advancement in surgical methods. Various grafts have been tried for myringoplasty time to time with varying results. Methods: A case control study was conducted; where 52 patients underwent myringoplasty with butterfly graft and second group of 52 patients underwent myringoplasty with temporalis fascia graft under general anesthesia in major OT. All the patients were followed up for 3 months. The results of the procedure were assessed, with respect to closure of tympanic membrane perforations and improvement in the air bone gap post operatively. Results: Butterfly group had statistically significant number of healed patients and hearing improvement compared to temporalis fascia group at the end of one month and with no statistical significance at the end of three months. The age group less than 18 years showed better uptake with butterfly graft. The difference of mean pre-operative, 1 month and 3 months post-operative air bone gaps in butterfly graft were 35.57±2.87 dB, 27.86±2.53 dB, 24.65±2.66dB and in temporalis fascia were 35.97±2.6dB, 29.36±1.54dB, 25.12±1.73 dB respectively. Conclusions: Butterfly group had statistically significant hearing improvement in patients compared to temporalis fascia group at one month and with no statistical significance at three months post procedure. The age group less than 18 years showed better uptake with butterfly graft.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139231109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An alarming case of metallic sharp foreign body ingestion in an infant 一个令人震惊的婴儿金属尖锐异物误食病例
Pub Date : 2023-11-27 DOI: 10.18203/issn.2454-5929.ijohns20233585
Sonali Malhotra
Foreign body ingestion is a frequent challenge in the emergency room, with potential morbidity affecting around 1% of patients, often stemming from unintentional incidents. Accidents of this nature can result in severe complications leading to fatalities. Common complications involve lacerations, punctures, abscess formation, perforation, pneumomediastinum, mediastinitis, pneumothorax, pericarditis, tamponade, fistulas, and even vascular injuries to the aorta. The risk escalates significantly when the ingested object is sharp and narrow. Presenting an intriguing case, we report an instance of an infant ingesting a metallic, sharp foreign body. This particular case raises unique challenges given the vulnerability of the infant and the potential for severe complications associated with sharp objects. Immediate and precise medical intervention becomes paramount in such scenarios to prevent adverse outcomes. Vigilance in the emergency room is crucial, as the nature of foreign body ingestion can lead to diverse complications, emphasizing the need for a comprehensive understanding and swift response in managing these cases, particularly when involving infants who are at a heightened risk.
异物摄入是急诊室经常遇到的难题,约有 1%的患者可能会因此而发病,而这通常源于意外事件。此类事故可导致严重并发症,甚至死亡。常见的并发症包括撕裂伤、穿刺、脓肿形成、穿孔、气胸、纵隔炎、气胸、心包炎、心肌填塞、瘘管,甚至主动脉血管损伤。如果食入的物体尖锐而狭窄,风险就会大大增加。我们报告了一个有趣的病例,一名婴儿误食了金属尖锐异物。鉴于婴儿的脆弱性以及锐利物体可能带来的严重并发症,这一特殊病例提出了独特的挑战。在这种情况下,立即进行精确的医疗干预以防止不良后果的发生变得至关重要。急诊室的警惕性至关重要,因为异物摄入的性质可能会导致多种并发症,这就强调了在处理这些病例时需要全面的了解和迅速的反应,尤其是在涉及风险较高的婴儿时。
{"title":"An alarming case of metallic sharp foreign body ingestion in an infant","authors":"Sonali Malhotra","doi":"10.18203/issn.2454-5929.ijohns20233585","DOIUrl":"https://doi.org/10.18203/issn.2454-5929.ijohns20233585","url":null,"abstract":"Foreign body ingestion is a frequent challenge in the emergency room, with potential morbidity affecting around 1% of patients, often stemming from unintentional incidents. Accidents of this nature can result in severe complications leading to fatalities. Common complications involve lacerations, punctures, abscess formation, perforation, pneumomediastinum, mediastinitis, pneumothorax, pericarditis, tamponade, fistulas, and even vascular injuries to the aorta. The risk escalates significantly when the ingested object is sharp and narrow. Presenting an intriguing case, we report an instance of an infant ingesting a metallic, sharp foreign body. This particular case raises unique challenges given the vulnerability of the infant and the potential for severe complications associated with sharp objects. Immediate and precise medical intervention becomes paramount in such scenarios to prevent adverse outcomes. Vigilance in the emergency room is crucial, as the nature of foreign body ingestion can lead to diverse complications, emphasizing the need for a comprehensive understanding and swift response in managing these cases, particularly when involving infants who are at a heightened risk.","PeriodicalId":14350,"journal":{"name":"International Journal of Otorhinolaryngology and Head and Neck Surgery","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Otorhinolaryngology and Head and Neck Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1