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Platelet-Rich Plasma Therapy with Excelents Results in the Treatment of Post-Infectious Telogen Effluvium 富血小板血浆疗法治疗感染后休止期积液效果良好
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2734
Gabriella Beltrame Pintos, Gabriela Batiston Tomasi, Camila Klotz, Laura Figueiredo Villa, João Roberto Antonio, Eduardo Vilela de Andrade, Nathan Lacerda Paulo, Bianca Pansanato Osada
Telogen Effluvium is defined as diffuse hair loss without scarring of the scalp which occurs after a stressful event. The storm of inflammatory cytokines can lead to the premature interruption of the anagen phase, resulting in excessive hair loss. The diagnosis is clinical. A 67-year-old woman with a previous diagnosis of stabilized androgenetic alopecia was infected with SARS-CoV-2 and, two months later, sought dermatological care due to intense hair loss. Telogen Effluvium was diagnosed in addition to her existing condition. Treatment involved the infiltration of active agents, combined with red LED and Fraxel laser in the affected area of the scalp, alternating with intralesional Platelet-Rich Plasma (PRP) injections into the scalp. Daily use of finasteride and oral biotin, along with topical minoxidil, was also part of the therapy. The result was significant hair recovery. Further research is needed to better define treatment guidelines.
休止期脱发被定义为在压力事件后发生的弥漫性脱发,头皮没有疤痕。炎症细胞因子的风暴可导致生长期过早中断,导致过度脱发。诊断是临床的。一名67岁妇女感染了SARS-CoV-2,此前诊断为稳定的雄激素源性脱发,两个月后因严重脱发而寻求皮肤科治疗。除她现有的情况外,还诊断出休止期流涎。治疗包括在头皮患处浸润活性药物,结合红色LED和Fraxel激光,交替向头皮内注射富血小板血浆(PRP)。每日使用非那雄胺和口服生物素,以及外用米诺地尔也是治疗的一部分。结果是头发明显恢复。需要进一步的研究来更好地确定治疗指南。
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引用次数: 0
The RUSI Mask is an Authentic Replicate of the Original Death Mask of Napoléon 入寺面具是一个真实的复制原来的死亡面具的纳波塞姆
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2696
G. Lucotte, François Jullien, T. Thomasset
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引用次数: 0
Feasibility Study on the Financing of Oil Trade Warehouse Receipts in China (Zhejiang) Pilot Free Trade Zone Based on Digital Supervision 基于数字监管的中国(浙江)自由贸易试验区石油贸易仓单融资可行性研究
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2664
Rulang Wang, Mengli Wang, Lei Lyu
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引用次数: 1
Synthesis and Photophysical Characterization of a Photoaffinity Molecular Switch 一种光亲和分子开关的合成及光物理特性研究
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2715
Shude Pang, Yingying Shi, Yanru Zhang
In recent years, the development of some photoswitches based on azobenzene group provides a good tool for high spatio-temporal and precise regulation of ion channels and protein receports, but these small molecular photoswitches are very easily diffused in organisms. To overcome this limit, we have designed a photoswitches SY1 containing photocrosslinked group diazirine. The photoswitch was synthesized by the condensation reaction between azobenzene derivative and diazirine. The structure of the compound was characterized by 1H NMR and HR-MS, and the photophysical properties of the photoswtich SY1 were studied by UV-vis spectroscopy in different solvent systems. The results show that SY1 has excellent photodependent isomerization.
近年来,一些基于偶氮苯基的光开关的发展为离子通道和蛋白质受体的高时空精确调控提供了良好的工具,但这些小分子光开关在生物体内非常容易扩散。为了克服这一限制,我们设计了一种含有光交联基团重氮嘧啶的光开关SY1。通过偶氮苯衍生物与重氮嘧啶的缩合反应合成了光开关。采用1H NMR和HR-MS对化合物的结构进行了表征,并利用紫外可见光谱研究了该光开关SY1在不同溶剂体系中的光物理性质。结果表明,SY1具有良好的光依赖性异构化反应。
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引用次数: 0
Nutritional Composition and Clinical Tolerance of a Food Plant in Female Wistar Rats: The Case of Moringa oleifera Species 一种雌性Wistar大鼠食用植物的营养成分和临床耐受性:以辣木为例
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2730
Adepo Yapo Prosper, FOFANA Ibrahim, Dembelé Syndoux
Moringa oleifera L. is a plant used throughout the world in many fields, including agriculture, health and nutrition. Moringa oleifera leaves are consumed throughout West Africa, particularly in Côte d'Ivoire by vulnerable populations. With a view to enhancing the value of the Moringa oleifera plant, a contribution to nutritional composition and clinical tolerance in rats force-fed an aqueous extract of this plant was studied. The study was carried out experimentally on 12 adult female Albino Wistar rats divided into two (2) batches of six (6) rats. The first batch received distilled water by gavage (twice a day for 4 days), while the second received the aqueous extract of Moringa oleifera at 0.2 g/mL by gavage. Nutritional composition indicated protein, lipid, carbohydrate, ash and dietary fiber contents of 26.12±0.18%; 6.8±0.13%; 14.37±0.26%; 9.5±0.67% and 43.2±0.519% respectively. Acidity and pH values were also 1.1±0.0 meq/100 g and 5.3±0.00 respectively. After observation, all animals survived for the duration of the experiment and showed no adverse clinical signs. This shows that the aqueous extract of Moringa oleifera is not only rich in nutrients, but is also clinically tolerated by rats. These results open up interesting prospects for the use of the Moringa oleifera plant in the form of an alicament that could be an effective means of combating public health diseases in breastfeeding women.
辣木(Moringa oleifera L.)是一种在世界范围内广泛使用的植物,包括农业、保健和营养。整个西非,特别是Côte科特迪瓦的弱势群体都在食用辣木叶。为了提高辣木植物的价值,研究了强行喂食辣木水提物对大鼠营养成分和临床耐受性的影响。本研究以12只成年雌性白化Wistar大鼠为实验对象,每组6只,分为2批。第一批灌胃蒸馏水(每天2次,连续4天),第二批灌胃辣木水提物(0.2 g/mL)。营养成分表明,蛋白质、脂肪、碳水化合物、灰分和膳食纤维含量为26.12±0.18%;6.8±0.13%;14.37±0.26%;分别为9.5±0.67%和43.2±0.519%。酸度和pH值分别为1.1±0.0 meq/100 g和5.3±0.00。经观察,所有动物在实验期间均存活,无不良临床症状。这说明辣木水提物不仅营养丰富,而且在临床上也被大鼠耐受。这些结果开辟了一个有趣的前景,即利用辣木植物作为一种添加剂,可能成为对抗母乳喂养妇女公共卫生疾病的有效手段。
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引用次数: 0
Testicular Tuberculosis: Case Report and Diagnostic Challenge 睾丸结核:病例报告和诊断挑战
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2733
Gabriella Beltrame Pintos, Adriano Silvério da Paixão, Vinicius Costa Lopes, Thiago da Silveira Antoniassi, Henrique Rabelo Cortines, Guilherme Cerqueira Gonzales, Rafael de Souza Aguiar, Daniel Salerno Muzilli, Eduardo Bueno Silveira, Caio Trajano Siqueira Salgado
Tuberculosis is a chronic infectious disease caused by the bacterium Mycobacterium tuberculosis, often associated with pulmonary infection. It is essential to recognize that this pathology can manifest in various parts of the body. The most common extrapulmonary manifestation is in the genitourinary system. The diagnosis of testicular tuberculosis is often complicated, as the symptoms can be nonspecific and overlap with other testicular conditions. A case was reported of a male patient, incarcerated, with a painless, indurated lesion in the left scrotum, evolving over approximately 5 months, who was later diagnosed with testicular tuberculosis. Emphasizing the importance of considering this differential diagnosis in patients with epididymitis that is difficult to resolve and who belong to risk populations, for appropriate treatment.
结核病是一种由结核分枝杆菌引起的慢性传染病,常伴有肺部感染。必须认识到这种病理可以在身体的各个部位表现出来。最常见的肺外表现是泌尿生殖系统。睾丸结核的诊断往往是复杂的,因为症状可能是非特异性的,并与其他睾丸疾病重叠。报告一例男性患者,监禁,无痛,硬化病变在左阴囊,发展约5个月,谁后来被诊断为睾丸结核。强调在难以解决的附睾炎患者和属于危险人群中考虑这种鉴别诊断的重要性,以便进行适当的治疗。
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引用次数: 0
Introduction to Rusho’s Transform Lakshmann and Smith Model: A Machine Learning Approach to Earthquake Detection Rusho’s Transform Lakshmann and Smith模型简介:一种地震检测的机器学习方法
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2646
Maher Ali Rusho
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引用次数: 0
Zap the Lead Problem: Cost-effective and Immediate Electrochemical Pipe Scale Accelerator 消除铅的问题:成本效益和即时电化学管道结垢加速器
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2682
Justin Juwan Yu
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引用次数: 0
Postoperative Presentation of Lumbar Spinal Stenosis: A Case and Review of the Literature 腰椎管狭窄症的术后表现:1例及文献回顾
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2652
Shuai Zheng, Pan Zhou, Liu ShuangJiang, Genlong Jiao
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引用次数: 0
Medicinal Cannabis for Patients with Fibromyalgia: A Review 药用大麻治疗纤维肌痛:综述
Pub Date : 2023-01-01 DOI: 10.18483/ijsci.2702
Valdecir Carlos Tadei, Bruna Oliveira Lopes, Leonardo Lourenço Zukeran, Isabela Maraccini Chueire, Laís Franciele Santana Portela, Regina Helena Morganti Fornari Chueire
{"title":"Medicinal Cannabis for Patients with Fibromyalgia: A Review","authors":"Valdecir Carlos Tadei, Bruna Oliveira Lopes, Leonardo Lourenço Zukeran, Isabela Maraccini Chueire, Laís Franciele Santana Portela, Regina Helena Morganti Fornari Chueire","doi":"10.18483/ijsci.2702","DOIUrl":"https://doi.org/10.18483/ijsci.2702","url":null,"abstract":"","PeriodicalId":14423,"journal":{"name":"International journal of sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78906469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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