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Synergistic effects of zP-1 phage and ampicillin against methicillin-resistant Staphylococcus aureus isolated from hospital staff.
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-06 DOI: 10.1007/s11845-025-03898-4
Zain Mehmood, Rabia Kanwar, Kaleem Ullah, Saqib Ali, Muhammad Aamir Aslam, Abdul Qadeer, Haiwad Gul, Mohamed Hassanein Mahmoud

Background: Methicillin-resistant Staphylococcus aureus (MRSA) strains are a major cause of hospital-acquired infections, exacerbated by increasing antibiotic resistance.

Aim: This study aimed to isolate bacteriophages targeting MRSA and evaluate their antimicrobial activity in combination with antibiotics.

Methods: Nasal samples from hospital staff (n = 50) were used to isolate MRSA strains, and sewage samples were processed for phage isolation using the double agar overlay technique. The microtitration plate method evaluated the synergistic effects of isolated phages and antibiotics.

Results: Out of 50 samples, 11 MRSA strains were positive, showing high resistance to multiple antibiotics, including oxacillin (95%), and vancomycin (85%). Phage zP-1, belonging to the Myoviridae family, exhibited > 90% lytic activity, stable across temperatures (20-50 °C) and pH (6-8). A statistically significant synergistic effect was observed at a MIC of 0.137 μg/ml for gentamicin (p-value 0.02).

Conclusion: These findings suggest that phage-antibiotic synergy may offer a promising strategy to combat MRSA infections, warranting further in vivo studies to assess its clinical potential.

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引用次数: 0
Burnout, wearing thin, and the courage to walk away.
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-06 DOI: 10.1007/s11845-025-03901-y
Frank Houghton
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引用次数: 0
Cost analysis of limb salvage: comparing limb revascularisation and amputation in patients with Chronic Limb-Threatening Ischaemia (CLTI) at University Hospital Limerick.
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-06 DOI: 10.1007/s11845-025-03885-9
Anne Marie Toomey, Fiona Leahy, Helen Purtill, Norma O'Brien, Emer O'Donovan, Zeeshan Ahmed, Mekki Medani, Tony Moloney, Eamon G Kavanagh

Background: The prevalence of peripheral arterial disease (PAD) is increasing globally. An increase in PAD in an ageing population inevitably results in an increase in incidence of Chronic Limb Threatening Ischemia (CLTI). Loss of a limb is a life-changing event with immeasurable cost to the individual, while the potential financial benefit of saving a limb is not well documented.

Aims: The focus of this study was to estimate the cost associated with surgical interventions used in the treatment of CLTI compared with amputation.

Methods: The cost to treat a CLTI diagnosis in 124 patients was analysed in an acute tertiary referral hospital over a 13-month study period. The analysis included staffing, medical devices used, number of blood components used and the length of stay. Statistical methods included descriptive statistical data and the Mann-Whitney U test.

Results: The median cost, associated with length of stay, post-amputation and post-revascularisation (hybrid) was €61,313 [IQR = €44,417, €83,331] and €46,573 [IQR = €25,687, €58,554] respectively, p < 0.001. The total median cost for length of stay for amputees in an acute hospital, rehabilitation and a prosthetic limb was €88,820 [IQR = €74,486, €110,248]. The median surgical cost of an amputation was €2,064 [IQR = €1,342, €2,866], whilst the median surgical cost of a revascularisation procedure (hybrid) was €5,966 [IQR = €4,380, €7,723], p < 0.001, inclusive of total blood components transfused.

Conclusion: Revascularisation surgical interventions are more expensive than amputation, however, the length of stay, rehabilitation and prosthetic limb costs, for a patient undergoing a major limb amputation, is significantly more costly.

{"title":"Cost analysis of limb salvage: comparing limb revascularisation and amputation in patients with Chronic Limb-Threatening Ischaemia (CLTI) at University Hospital Limerick.","authors":"Anne Marie Toomey, Fiona Leahy, Helen Purtill, Norma O'Brien, Emer O'Donovan, Zeeshan Ahmed, Mekki Medani, Tony Moloney, Eamon G Kavanagh","doi":"10.1007/s11845-025-03885-9","DOIUrl":"https://doi.org/10.1007/s11845-025-03885-9","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of peripheral arterial disease (PAD) is increasing globally. An increase in PAD in an ageing population inevitably results in an increase in incidence of Chronic Limb Threatening Ischemia (CLTI). Loss of a limb is a life-changing event with immeasurable cost to the individual, while the potential financial benefit of saving a limb is not well documented.</p><p><strong>Aims: </strong>The focus of this study was to estimate the cost associated with surgical interventions used in the treatment of CLTI compared with amputation.</p><p><strong>Methods: </strong>The cost to treat a CLTI diagnosis in 124 patients was analysed in an acute tertiary referral hospital over a 13-month study period. The analysis included staffing, medical devices used, number of blood components used and the length of stay. Statistical methods included descriptive statistical data and the Mann-Whitney U test.</p><p><strong>Results: </strong>The median cost, associated with length of stay, post-amputation and post-revascularisation (hybrid) was €61,313 [IQR = €44,417, €83,331] and €46,573 [IQR = €25,687, €58,554] respectively, p < 0.001. The total median cost for length of stay for amputees in an acute hospital, rehabilitation and a prosthetic limb was €88,820 [IQR = €74,486, €110,248]. The median surgical cost of an amputation was €2,064 [IQR = €1,342, €2,866], whilst the median surgical cost of a revascularisation procedure (hybrid) was €5,966 [IQR = €4,380, €7,723], p < 0.001, inclusive of total blood components transfused.</p><p><strong>Conclusion: </strong>Revascularisation surgical interventions are more expensive than amputation, however, the length of stay, rehabilitation and prosthetic limb costs, for a patient undergoing a major limb amputation, is significantly more costly.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of shearing wave elastography in detecting early diabetic nephropathy.
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-06 DOI: 10.1007/s11845-025-03897-5
Amr M Shaker, Shaza Y Sleem, Mayssa I Aly, Asmaa H Habib, Mona G Hassan

Background: Diabetes mellitus is one of the systemic diseases affecting the kidneys that eventually develop end-stage kidney disease. Shear wave elastography (SWE) is a reliable and non-invasive ultrasonography test used to determine tissue elasticity. The aim of this study is to detect early diabetic nephropathy by measuring renal stiffness using shear wave elastography (SWE), renal resistivity indices, and laboratory findings in DN patients.

Methods: Shear wave elastography and color duplex sonography assessments were performed in 60 diabetic nephropathy patients (divided according to eGFR into 3 stages: stage I-II-III diabetic nephropathy with equal groups of 20 patients in each stage) and 20 healthy age-matched control subjects. The SWE-derived mean value of the tissue stiffness, given in kilopascals (kPa), was correlated to patients' clinico-laboratory data (serum creatinine and eGFR) and resistive index.

Results: There is a statistically significant increase in SWE and RI in the diabetic group than control group and a statistically significant increase in SWE (mean) in CKD stage II and III when compared with CKD stage I, SWE can be used to discriminate between diabetic groups and control group at a cutoff level of > 10.5 (kPa), and also, SWE (mean) can be used to discriminate between CKD stage II and III patients at a cutoff level of > 41 (kPa), with 66.7% sensitivity and 64.9% specificity.

Conclusion: Shear wave elastography is a sensitive, non-invasive, and specific diagnostic tool for the detection of diabetic nephropathy and differentiation between different stages of DN.

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引用次数: 0
Neurologists' perspectives of cannabis-based medicines: results from an all-Ireland survey.
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-03 DOI: 10.1007/s11845-025-03880-0
Michael Savio, Hugh Kearney, Eric J Downer

Background: Advancements continue to be made in the development of medicines containing components of the Cannabis sativa L. plant. Consultants can prescribe specific cannabis-based products for a restricted set of indications in Ireland, with neurologists being at the forefront of therapy. Much debate on the therapeutic potential/efficacy of such cannabis-based products exists.

Aim: The objective of this study was to conduct a national survey to determine the perspectives/views of Irish neurologists regarding the use of cannabis-based medicines.

Methods: An online anonymous survey was conducted to capture the perspectives and experiences of neurologists in Ireland regarding cannabis-based therapeutics.

Results: Thirty-four neurologists completed the survey in full, with study participants rating their knowledge of cannabis-based medicines as average. Data presented herein indicate that there is a need for educational programmes on the cannabinoid system and cannabinoid-based medicines, and the findings indicate that neurologists are interested in the use of cannabinoid-based medicines in their practice. Study participants were more divided with regard to the clarity of the process for accessing cannabis-based medicines, and the consensus is that the application process is unclear. Approximately one-third of participants have made an application to access medicinal cannabis-based products on behalf of a patient.

Conclusions: Data presented herein indicates that the majority of neurologists surveyed are aware of the current systems in place to access cannabis-based products for medicinal use in Ireland and that some engagement with these systems has taken place. A key finding is that educational programmes on the cannabinoid system and cannabis-based medicines are required.

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引用次数: 0
Functional outcomes of inspiratory muscle training in elderly with intensive care unit-acquired weakness and severe walking disability.
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-03 DOI: 10.1007/s11845-025-03876-w
Mushabbab Alahmari, Hany Farid Elsisi, Ali Mohamed Ali Ismail

Background: Intensive care unit acquired-weakness syndrome (ICUAWS) leaves several complications in functional movements of patients such as severe walking disability.

Objective: Assessment of functional outcomes of 1-month inspiratory muscle training (IMT) in elderly with ICUAWS and severe walking disability was our aim. The design, setting, participants, and intervention. This study is a randomized controlled trial. ICUAWS patients who complained of severe walking disability on the Modified Functional Ambulatory Category Test (MFACT) were randomly assigned into the IMT group or control group, n = 20 for each group. Both groups received the traditional physical therapy program.

Results: The results showed that the post-therapy between-group comparison of ICUAWS sufferers/groups' parameters showed a significant improvement toward the IMT group in six-minute walk test, inspiratory and expiratory muscle strength, forced vital capacity, time up and go test, 10-m walk test, forced expiratory volume in the first second, 30-s sit-to-stand test, partial pressure of arterial blood oxygen and carbon dioxide, MFACT, oxygen saturation of arterial blood, physical, and mental summary of short form 36.

Conclusion: In conclusion, IMT improves functional outcomes in ICUAWS patients with walking disability.

Trial registration number: The clinical trial ID of this ICUAWS trial is NCT06210763.

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引用次数: 0
Hepatotoxicity in spaceflight: intrinsic and extrinsic risks for astronaut metabolic health.
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-03 DOI: 10.1007/s11845-025-03884-w
Ethan Waisberg, Joshua Ong, Mouayad Masalkhi, Ben Cools, Ryung Lee, Mathieu Vinken, Andrew G Lee
{"title":"Hepatotoxicity in spaceflight: intrinsic and extrinsic risks for astronaut metabolic health.","authors":"Ethan Waisberg, Joshua Ong, Mouayad Masalkhi, Ben Cools, Ryung Lee, Mathieu Vinken, Andrew G Lee","doi":"10.1007/s11845-025-03884-w","DOIUrl":"https://doi.org/10.1007/s11845-025-03884-w","url":null,"abstract":"","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of acute psychiatric inpatient length of stay in Ireland. 爱尔兰急性精神病住院病人住院时间的决定因素。
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2024-10-15 DOI: 10.1007/s11845-024-03819-x
Aoife Brick, Brendan Walsh, Leonie Hill, Caragh Behan, Antoinette Daly, Sarah Craig

Background: Ireland has had an historic over-reliance on inpatient mental health care accompanied by poorly resourced community provision. There has been an increasing policy focus on provision of mental health care in the community to facilitate diversion from, or shorten stays in, inpatient care. However, little is known about the determinants of psychiatric inpatient length of stay (LOS) to allow for the targeting of community services.

Aim: To use a large cross-sectional national dataset to examine the determinants of psychiatric inpatient LOS in the Irish context.

Methods: Using information on 60,607 discharges from adult acute psychiatric units in Ireland between 2015 and 2019, the study employs both descriptive and regression analysis. Using negative binomial regression models, we control for patient demographic, socioeconomic, and clinical characteristics. In addition, as LOS may be related to provision of non-acute services in the patient area of residence, the analysis also controls for aspects of community service provision.

Results: The study finds that longer LOS is associated with older age, being female, and having an involuntary admission. Clinical diagnosis significantly impacts LOS, with diagnoses such as schizophrenia being associated with longer LOS. There is also significant variation in LOS across region of residence, with discharges from some regions staying up to 5 days longer.

Conclusions: The regional variation observed in inpatient LOS supports the assumption that increased provision of community services diverts or reduces the quantum of care required in inpatient settings. However, without substantive improvement in the community data collected and reported, future planning of mental health services, both community and inpatient, will be substantially curtailed.

背景:爱尔兰历来过度依赖住院病人的精神健康护理,而社区提供的护理资源却很匮乏。政策上越来越重视在社区提供精神健康护理,以促进住院病人的分流或缩短住院时间。然而,人们对精神病患者住院时间(LOS)的决定因素知之甚少,因此无法有针对性地提供社区服务。目的:利用一个大型横截面全国数据集,研究爱尔兰精神病患者住院时间的决定因素:该研究使用了 2015 年至 2019 年期间爱尔兰 60607 名成人急性精神病科出院者的信息,采用了描述性分析和回归分析。利用负二项回归模型,我们控制了患者的人口、社会经济和临床特征。此外,由于住院时间可能与患者居住地提供的非急性期服务有关,因此分析还控制了社区服务提供的各个方面:研究发现,住院时间较长与年龄较大、女性和非自愿入院有关。临床诊断对 LOS 有重大影响,精神分裂症等诊断与较长的 LOS 有关。不同居住地区的住院时间也有很大差异,一些地区的出院病人住院时间最多可延长 5 天:住院病人生命周期的地区差异支持这样一种假设,即社区服务的增加可以分流或减少住院病人所需的护理量。然而,如果不对社区数据的收集和报告进行实质性的改进,那么未来的精神健康服务规划,包括社区服务和住院服务,都将受到极大的限制。
{"title":"Determinants of acute psychiatric inpatient length of stay in Ireland.","authors":"Aoife Brick, Brendan Walsh, Leonie Hill, Caragh Behan, Antoinette Daly, Sarah Craig","doi":"10.1007/s11845-024-03819-x","DOIUrl":"10.1007/s11845-024-03819-x","url":null,"abstract":"<p><strong>Background: </strong>Ireland has had an historic over-reliance on inpatient mental health care accompanied by poorly resourced community provision. There has been an increasing policy focus on provision of mental health care in the community to facilitate diversion from, or shorten stays in, inpatient care. However, little is known about the determinants of psychiatric inpatient length of stay (LOS) to allow for the targeting of community services.</p><p><strong>Aim: </strong>To use a large cross-sectional national dataset to examine the determinants of psychiatric inpatient LOS in the Irish context.</p><p><strong>Methods: </strong>Using information on 60,607 discharges from adult acute psychiatric units in Ireland between 2015 and 2019, the study employs both descriptive and regression analysis. Using negative binomial regression models, we control for patient demographic, socioeconomic, and clinical characteristics. In addition, as LOS may be related to provision of non-acute services in the patient area of residence, the analysis also controls for aspects of community service provision.</p><p><strong>Results: </strong>The study finds that longer LOS is associated with older age, being female, and having an involuntary admission. Clinical diagnosis significantly impacts LOS, with diagnoses such as schizophrenia being associated with longer LOS. There is also significant variation in LOS across region of residence, with discharges from some regions staying up to 5 days longer.</p><p><strong>Conclusions: </strong>The regional variation observed in inpatient LOS supports the assumption that increased provision of community services diverts or reduces the quantum of care required in inpatient settings. However, without substantive improvement in the community data collected and reported, future planning of mental health services, both community and inpatient, will be substantially curtailed.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"211-223"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of norepinephrine in the treatment of septic shock: a meta-analysis. 去甲肾上腺素在脓毒性休克治疗中的应用:一项荟萃分析。
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2024-11-09 DOI: 10.1007/s11845-024-03827-x
Qiu Ying Xu, Yan Hong Jin, Li Fu, Ying Ying Li

Objective: To systematically evaluate the efficacy and safety of norepinephrine in the treatment of septic shock.

Methods: Literature retrieval of eligible randomized controlled trials (RCTs) on norepinephrine in the treatment of septic shock was performed in three English databases including PubMed, Web of Science, and Medline from database establishment to October 1, 2023. The Cochrane risk bias tool was used to evaluate the quality of the included literature. RevMan 5.3 software was used for meta-analysis.

Results: A total of 14 RCTs were included in this study, and the risk of bias was low. Our meta-analysis showed that the norepinephrine group had significantly better outcomes in reducing the 28-day mortality rate (RR = 0.92; 95% CI, 0.86 ~ 0.99; P = 0.03), the incidence of arrhythmia (RR = 0.54; 95% CI, 0.45 ~ 0.64; P < 0.0001), and the length of stay in intensive care unit (ICU) (MD =  - 1.03; 95% CI, - 1.85 to approximately - 0.21; P = 0.01) than those of the control group. However, there were no statistically significant differences in in-hospital mortality rate (RR = 0.97; 95% CI, 0.90 ~ 1.04; P = 0.4), the 90-day mortality rate (RR = 1.07; 95% CI, 0.97 ~ 1.18; P = 0.15), length of hospital stay (MD = 0.03; 95% CI, - 1.13 ~ 1.18; P = 0.96), and the rate of achieving target MAP (RR = 1.27; 95% CI, 0.72 ~ 2.26; P = 0.41) between the norepinephrine group and the control group.

Conclusion: Norepinephrine has the advantages of improving 28-day mortality, shortening ICU hospitalization time, and reducing the incidence of arrhythmia. It is a more effective choice for the treatment of septic shock than other vasopressors, and the incidence of arrhythmia is low.

目的:系统评估去甲肾上腺素治疗脓毒性休克的有效性和安全性:系统评估去甲肾上腺素治疗脓毒性休克的有效性和安全性:从数据库建立到 2023 年 10 月 1 日,在三个英文数据库(包括 PubMed、Web of Science 和 Medline)中对去甲肾上腺素治疗脓毒性休克的合格随机对照试验(RCT)进行了文献检索。科克伦风险偏倚工具用于评估纳入文献的质量。使用RevMan 5.3软件进行荟萃分析:本研究共纳入了 14 篇研究性临床试验,偏倚风险较低。我们的荟萃分析表明,去甲肾上腺素组在降低 28 天死亡率(RR = 0.92;95% CI,0.86 ~ 0.99;P = 0.03)、心律失常发生率(RR = 0.54;95% CI,0.45 ~ 0.64;P去甲肾上腺素具有改善 28 天死亡率、缩短 ICU 住院时间和降低心律失常发生率的优势。与其他血管加压药相比,去甲肾上腺素是治疗脓毒性休克的更有效选择,且心律失常发生率低。
{"title":"Application of norepinephrine in the treatment of septic shock: a meta-analysis.","authors":"Qiu Ying Xu, Yan Hong Jin, Li Fu, Ying Ying Li","doi":"10.1007/s11845-024-03827-x","DOIUrl":"10.1007/s11845-024-03827-x","url":null,"abstract":"<p><strong>Objective: </strong>To systematically evaluate the efficacy and safety of norepinephrine in the treatment of septic shock.</p><p><strong>Methods: </strong>Literature retrieval of eligible randomized controlled trials (RCTs) on norepinephrine in the treatment of septic shock was performed in three English databases including PubMed, Web of Science, and Medline from database establishment to October 1, 2023. The Cochrane risk bias tool was used to evaluate the quality of the included literature. RevMan 5.3 software was used for meta-analysis.</p><p><strong>Results: </strong>A total of 14 RCTs were included in this study, and the risk of bias was low. Our meta-analysis showed that the norepinephrine group had significantly better outcomes in reducing the 28-day mortality rate (RR = 0.92; 95% CI, 0.86 ~ 0.99; P = 0.03), the incidence of arrhythmia (RR = 0.54; 95% CI, 0.45 ~ 0.64; P < 0.0001), and the length of stay in intensive care unit (ICU) (MD =  - 1.03; 95% CI, - 1.85 to approximately - 0.21; P = 0.01) than those of the control group. However, there were no statistically significant differences in in-hospital mortality rate (RR = 0.97; 95% CI, 0.90 ~ 1.04; P = 0.4), the 90-day mortality rate (RR = 1.07; 95% CI, 0.97 ~ 1.18; P = 0.15), length of hospital stay (MD = 0.03; 95% CI, - 1.13 ~ 1.18; P = 0.96), and the rate of achieving target MAP (RR = 1.27; 95% CI, 0.72 ~ 2.26; P = 0.41) between the norepinephrine group and the control group.</p><p><strong>Conclusion: </strong>Norepinephrine has the advantages of improving 28-day mortality, shortening ICU hospitalization time, and reducing the incidence of arrhythmia. It is a more effective choice for the treatment of septic shock than other vasopressors, and the incidence of arrhythmia is low.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"361-369"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11861117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges for neurodiverse children in acute medical hospitals and opportunities for the new National Children's Hospital to be 'neurodiversity-friendly'. 急症医院神经多样性儿童面临的挑战和新国家儿童医院“神经多样性友好”的机遇。
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2024-12-17 DOI: 10.1007/s11845-024-03850-y
Laura Bond, Timothy Frawley, Kieran Moore, Blánaid Gavin, Fiona McNicholas

Neurodiversity refers to the variation in human cognitive, sensory, and communication experiences and reframes deficits as differences. Rates and duration of hospitalisation in neurodiverse children are higher compared to their neurotypical peers. Despite increased admissions, paediatric medical hospitals are poorly equipped to adequately support their unique cognitive, sensory, behavioural, and communication needs, which can have negative impacts on the experiences of patients, families, and staff. The literature supports several innovative and inclusive strategies, which present exciting opportunities for Ireland's new National Children's Hospital (NCH) to become a 'neurodiversity-friendly paediatric hospital'.

神经多样性是指人类在认知、感官和交流经验方面的差异,并将缺陷重塑为差异。与神经畸形儿童相比,神经多样性儿童的住院率更高,住院时间更长。尽管入院人数有所增加,但儿科医疗医院的设备不足,无法充分满足他们独特的认知、感官、行为和交流需求,这可能会对患者、家属和员工的体验产生负面影响。有文献支持几项创新性和包容性的策略,这些策略为爱尔兰新的国家儿童医院(NCH)成为 "神经多样性友好型儿科医院 "提供了令人兴奋的机遇。
{"title":"Challenges for neurodiverse children in acute medical hospitals and opportunities for the new National Children's Hospital to be 'neurodiversity-friendly'.","authors":"Laura Bond, Timothy Frawley, Kieran Moore, Blánaid Gavin, Fiona McNicholas","doi":"10.1007/s11845-024-03850-y","DOIUrl":"10.1007/s11845-024-03850-y","url":null,"abstract":"<p><p>Neurodiversity refers to the variation in human cognitive, sensory, and communication experiences and reframes deficits as differences. Rates and duration of hospitalisation in neurodiverse children are higher compared to their neurotypical peers. Despite increased admissions, paediatric medical hospitals are poorly equipped to adequately support their unique cognitive, sensory, behavioural, and communication needs, which can have negative impacts on the experiences of patients, families, and staff. The literature supports several innovative and inclusive strategies, which present exciting opportunities for Ireland's new National Children's Hospital (NCH) to become a 'neurodiversity-friendly paediatric hospital'.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"253-261"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Irish Journal of Medical Science
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