K. Shahsavarinia, G. Faridaalaee, H. Soleimanpour, Fatemeh Sadeghi-Ghyassi, Sanam Atashgahi, Nooshin Milanchian, N. Abolhasanpour, H. Salehi-pourmehr
{"title":"Cerebral Venous Thrombosis (CVT) Following COVID-19 Vaccination: an Umbrella Review of Systematic Reviews","authors":"K. Shahsavarinia, G. Faridaalaee, H. Soleimanpour, Fatemeh Sadeghi-Ghyassi, Sanam Atashgahi, Nooshin Milanchian, N. Abolhasanpour, H. Salehi-pourmehr","doi":"10.30699/ijmm.17.1.7","DOIUrl":"https://doi.org/10.30699/ijmm.17.1.7","url":null,"abstract":"","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42728720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ventilator Associated Tracheobronchitis – Etiology and Outcome at an Intensive Care Unit of a Tertiary Care Center in North India","authors":"B. Kakati, Nupur Koul, S. Agarwal","doi":"10.30699/ijmm.17.1.103","DOIUrl":"https://doi.org/10.30699/ijmm.17.1.103","url":null,"abstract":"","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45537295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Ramazanzadeh, Abdorazagh Marzban, Javad Khalili Fard Ardali, Reza Saki, H. Esmaeil Lashgarian, P. Shakib
{"title":"Anti-Mycobacterium tuberculosis Effects of Folk Medicinal Plants in Iran: A Mini-Systematic Review","authors":"R. Ramazanzadeh, Abdorazagh Marzban, Javad Khalili Fard Ardali, Reza Saki, H. Esmaeil Lashgarian, P. Shakib","doi":"10.30699/ijmm.17.1.1","DOIUrl":"https://doi.org/10.30699/ijmm.17.1.1","url":null,"abstract":"","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45590396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and Multi-Drug Resistance Patterns of Uropathogenic E.coli isolated from Women Patients in Kirkuk city, Iraq","authors":"T. Fakhraddin Raheem, Sarah Ahmed Hasan Ali","doi":"10.30699/ijmm.16.6.609","DOIUrl":"https://doi.org/10.30699/ijmm.16.6.609","url":null,"abstract":"","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47579022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Mokhtari, H. Kaboosi, S. Mohebbi, H. Asadzadeh Aghdaei, M. Zali
{"title":"Evaluation of Circulating MicroRNA-222 in Patients with Chronic Hepatitis B virus Infection as a Potential Noninvasive Diagnostic Biomarker","authors":"F. Mokhtari, H. Kaboosi, S. Mohebbi, H. Asadzadeh Aghdaei, M. Zali","doi":"10.30699/ijmm.16.6.543","DOIUrl":"https://doi.org/10.30699/ijmm.16.6.543","url":null,"abstract":"","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47319096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A molecular New Update on the Biofilm Production and Carbapenem Resistance Mechanisms in Clinical Pseudomonas aeruginosa Isolates","authors":"Raziyeh Ramazani, Rabeeh Izadi Amoli, Mojtaba Taghizadeh Armaki, Abazar Pournajaf, H. Kaboosi","doi":"10.30699/ijmm.16.6.557","DOIUrl":"https://doi.org/10.30699/ijmm.16.6.557","url":null,"abstract":"","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42924895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Aim: Vancomycin resistant Enterococci (VRE) and high level aminoglycoside resistant (HLAR) Enterococci have complicated the available treatment modalities for Enterococci worldwide. The existing study was planned to evaluate the occurrence of HLAR and VRE strains in a tertiary care center in India and to study the association of HLAR with vancomycin sensitive Enterococci (VSE) and VRE. Materials and Methods: A total of 50 enterococcal isolates from various clinical specimens were incorporated in the study. Speciation was done on the basis of standard biochemical tests. HLAR was tested by the disc diffusion method using 150µg gentamicin disc and 200 µg streptomycin discs. Vancomycin susceptibility patterns were reported using vancomycin disc and agar dilution methods. Results & Conclusion: Pus samples comprised of the majority for the isolation of enterococcal strains (40%). 54% isolated strains were HLGR, 32% were HLSR and 14% isolates were positive for both HLGR and HLSR. 61.7% of Enterococcus faecium isolates demonstrated resistance for high-level gentamicin (HLGR) and 43.75% Enterococcus faecalis isolates were resistant to high-level streptomycin (HLSR). When VRE was compared to VSE, the rate of HLSR was detected to be 4.64% in VRE, while it was 32.55% in VSE; the rate of HLGR was noted to be 11.62% in VRE and it was 41.87% in VSE. The association of HLGR with HLSR (HLAR) was 2.32% in VRE and 13.95% in VSE strains. Enterococci strains are showing an increase in their antimicrobial resistance patterns. The increment of such strains in health care settings has to be reserved and controlled to avert complicated infections.
{"title":"Prevalence of High Level Aminoglycoside Resistance and Vancomycin Resistance in Enterococcal Isolates at A Tertiary Care Hospital","authors":"Dimple Raina, Anjali Negi, A. Pandita, N. Rawat","doi":"10.30699/ijmm.16.5.472","DOIUrl":"https://doi.org/10.30699/ijmm.16.5.472","url":null,"abstract":"Background and Aim: Vancomycin resistant Enterococci (VRE) and high level aminoglycoside resistant (HLAR) Enterococci have complicated the available treatment modalities for Enterococci worldwide. The existing study was planned to evaluate the occurrence of HLAR and VRE strains in a tertiary care center in India and to study the association of HLAR with vancomycin sensitive Enterococci (VSE) and VRE. Materials and Methods: A total of 50 enterococcal isolates from various clinical specimens were incorporated in the study. Speciation was done on the basis of standard biochemical tests. HLAR was tested by the disc diffusion method using 150µg gentamicin disc and 200 µg streptomycin discs. Vancomycin susceptibility patterns were reported using vancomycin disc and agar dilution methods. Results & Conclusion: Pus samples comprised of the majority for the isolation of enterococcal strains (40%). 54% isolated strains were HLGR, 32% were HLSR and 14% isolates were positive for both HLGR and HLSR. 61.7% of Enterococcus faecium isolates demonstrated resistance for high-level gentamicin (HLGR) and 43.75% Enterococcus faecalis isolates were resistant to high-level streptomycin (HLSR). When VRE was compared to VSE, the rate of HLSR was detected to be 4.64% in VRE, while it was 32.55% in VSE; the rate of HLGR was noted to be 11.62% in VRE and it was 41.87% in VSE. The association of HLGR with HLSR (HLAR) was 2.32% in VRE and 13.95% in VSE strains. Enterococci strains are showing an increase in their antimicrobial resistance patterns. The increment of such strains in health care settings has to be reserved and controlled to avert complicated infections.","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49503504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yeganeh Malek Mohammadi, P. Khaki, S. Moradi Bidhendi, M. Noofeli
Background and Aim: Leptospirosis is one of the most common zoonotic diseases worldwide, occurring mostly in tropical, subtropical, temperate, and humid regions with heavy rainfall. It is important to diagnose this condition correctly and promptly. Loa22 is an outer membrane protein exposed to the surface in some Leptospira serovars. The purpose of this study was to determine the presence of the gene encoding Loa22 protein in Leptospira interrogans serovars. Materials and Methods: The present study was conducted on 23 pathogenic leptospira serovars and two non-pathogenic leptospira serovars. These serovars were prepared from the Reference Laboratory for Leptospira, Department of Microbiology, Razi Vaccine, and Serum Research Institute, Karaj, Iran. After genomic DNA extraction using the standard phenol-chloroform method, loa22 gene was amplified by specific primers. Results: PCR was performed on the loa22 gene by producing a 671-bp fragment. The results showed that the loa22 gene was present in all 23 pathogenic leptospira serovars but not in the non-pathogenic L. biflexa . The specificity of tested primers was confirmed as well. Conclusion: The loa22 gene is a specific gene for pathogenic leptospira serovars that is not found in saprophytic serovars, so it is suggested that this gene be used to detect leptospira pathogenic serovars.
{"title":"Evaluation of the Presence of Gene Encoding Loa22 in Pathogenic Leptospira Serovars","authors":"Yeganeh Malek Mohammadi, P. Khaki, S. Moradi Bidhendi, M. Noofeli","doi":"10.30699/ijmm.16.5.392","DOIUrl":"https://doi.org/10.30699/ijmm.16.5.392","url":null,"abstract":"Background and Aim: Leptospirosis is one of the most common zoonotic diseases worldwide, occurring mostly in tropical, subtropical, temperate, and humid regions with heavy rainfall. It is important to diagnose this condition correctly and promptly. Loa22 is an outer membrane protein exposed to the surface in some Leptospira serovars. The purpose of this study was to determine the presence of the gene encoding Loa22 protein in Leptospira interrogans serovars. Materials and Methods: The present study was conducted on 23 pathogenic leptospira serovars and two non-pathogenic leptospira serovars. These serovars were prepared from the Reference Laboratory for Leptospira, Department of Microbiology, Razi Vaccine, and Serum Research Institute, Karaj, Iran. After genomic DNA extraction using the standard phenol-chloroform method, loa22 gene was amplified by specific primers. Results: PCR was performed on the loa22 gene by producing a 671-bp fragment. The results showed that the loa22 gene was present in all 23 pathogenic leptospira serovars but not in the non-pathogenic L. biflexa . The specificity of tested primers was confirmed as well. Conclusion: The loa22 gene is a specific gene for pathogenic leptospira serovars that is not found in saprophytic serovars, so it is suggested that this gene be used to detect leptospira pathogenic serovars.","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43655724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Sadeghi, N. Gheibi, F. Karimi Dermani, Saeideh Gholamzadeh Khoei
Background and Aim: Urinary tract infections (UTIs) that influence millions of humans yearly are still among the most common infections in the community and hospitals. This study aimed to investigate the prevalence of UTIs and their antibiotic resistance susceptibility in patients in Qazvin province, northwest Iran, from 2017 to 2019. Materials and Methods: This study was conducted on 3521 urine samples of patients referred to a non-hospital medical laboratory (Mehr) between April 2017 and January 2019. Samples were collected and processed immediately for laboratory analysis. Biochemical tests were conducted the bacteria identification, and the antibiotic susceptibility test of the bacterial isolates was determined using Kirby-Bauer disc diffusion. Results & Conclusion: 347 of the 3521 urine samples had significant bacteriuria, with a prevalence of 9.9 %. Escherichia coli occurred more frequently (54.4 %), while Pseudomonas aeruginosa had the lowest frequency of occurrence (1.4 %) in the samples. Nitrofurantoin and Amikacin were the most effective antibiotics against gram-negative and positive, respectively. This study revealed that bacterial resistance in UTIs continues to be a great problem and needs drug resistance surveillance periodically.
{"title":"A Retrospective Cross-sectional Survey on Urinary Tract Infections in a Non-hospital Medical Laboratory","authors":"H. Sadeghi, N. Gheibi, F. Karimi Dermani, Saeideh Gholamzadeh Khoei","doi":"10.30699/ijmm.16.5.465","DOIUrl":"https://doi.org/10.30699/ijmm.16.5.465","url":null,"abstract":"Background and Aim: Urinary tract infections (UTIs) that influence millions of humans yearly are still among the most common infections in the community and hospitals. This study aimed to investigate the prevalence of UTIs and their antibiotic resistance susceptibility in patients in Qazvin province, northwest Iran, from 2017 to 2019. Materials and Methods: This study was conducted on 3521 urine samples of patients referred to a non-hospital medical laboratory (Mehr) between April 2017 and January 2019. Samples were collected and processed immediately for laboratory analysis. Biochemical tests were conducted the bacteria identification, and the antibiotic susceptibility test of the bacterial isolates was determined using Kirby-Bauer disc diffusion. Results & Conclusion: 347 of the 3521 urine samples had significant bacteriuria, with a prevalence of 9.9 %. Escherichia coli occurred more frequently (54.4 %), while Pseudomonas aeruginosa had the lowest frequency of occurrence (1.4 %) in the samples. Nitrofurantoin and Amikacin were the most effective antibiotics against gram-negative and positive, respectively. This study revealed that bacterial resistance in UTIs continues to be a great problem and needs drug resistance surveillance periodically.","PeriodicalId":14580,"journal":{"name":"Iranian Journal of Medical Microbiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46753586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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