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Unilateral endophthalmitis after immediate sequential bilateral cataract surgery in a cognitively impaired patient: diagnosis and treatment 认知障碍患者立即连续双侧白内障手术后单侧眼内炎的诊断和治疗
Q4 Medicine Pub Date : 2023-02-10 DOI: 10.1097/j.jcro.0000000000000091
Jaime D. Martinez, H. Levine, H. Flynn, S. G. Schwartz
Introduction: Immediate sequential bilateral cataract surgery (ISBCS) is a reasonable approach for cataract surgery in patients needing general anesthesia, such as those with cognitive impairment. To our knowledge, this is the first reported case of unilateral acute-onset postoperative endophthalmitis in a patient with cognitive impairment after ISBCS, with emphasis on diagnostic and treatment challenges. Patient and Clinical Findings: A 64-year-old woman with a history of cognitive impairment, seizure disorder, and no prior ocular surgery presented with dense visually significant cataracts and visual acuity of fix and follows in both eyes. Diagnosis, Intervention, and Outcomes: Patient underwent ISBCS under general anesthesia and without intracameral antibiotics or corneal sutures. The patient returned with unilateral acute-onset endophthalmitis 2 weeks postoperatively. Because of the patient's limited ability to comply with treatment, and lack of emergency general anesthesia needed for vitreous cultures, intravitreal vancomycin injection (1 mg/0.1 mL) was empirically given, with clinical resolution of the infection and visual acuity of fix and follows. Conclusions: Acute-onset postoperative endophthalmitis in the setting of cognitive impairment is challenging because emergency general anesthesia may not be available, and the patient can tolerate only limited interventions. In this patient, empiric intravitreal vancomycin injection without cultures led to a satisfactory clinical outcome.
引言:对于需要全身麻醉的患者,如认知障碍患者,即时顺序双侧白内障手术(ISBCS)是一种合理的白内障手术方法。据我们所知,这是第一例报道的ISBCS后认知障碍患者单侧急性发作的术后眼内炎,重点是诊断和治疗挑战。患者和临床发现:一名64岁的女性,有认知障碍、癫痫发作病史,既往未做过眼部手术,患有严重的视觉性白内障,双眼视力为固定及随访。诊断、干预和结果:患者在全身麻醉下接受了ISBCS,没有使用房内抗生素或角膜缝线。患者术后2周再次出现单侧急性眼内炎。由于患者遵守治疗的能力有限,并且缺乏玻璃体培养所需的紧急全身麻醉,因此根据经验给予玻璃体内万古霉素注射(1mg/0.1mL),临床上可解决感染和固定视力问题。结论:在认知障碍的情况下,急性发作的术后眼内炎具有挑战性,因为可能无法进行紧急全身麻醉,并且患者只能忍受有限的干预。在该患者中,未经培养的经验性玻璃体内注射万古霉素获得了令人满意的临床结果。
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引用次数: 0
Outcomes of very delayed onset chronic postoperative endophthalmitis caused by Cutibacterium acnes including treatment with endolaser photocoagulation 痤疮表皮杆菌引起的迟发性术后慢性眼内炎包括激光光凝治疗的结果
Q4 Medicine Pub Date : 2022-10-28 DOI: 10.1097/j.jcro.0000000000000086
Danny A. Mammo, Phuoc-Hanh Le, Sruthi Arepalli, S. Srivastava, Sumit Sharma
Introduction: To the authors' knowledge, these are 2 of the longest reported time periods between cataract surgery and diagnosis of chronic postoperative endophthalmitis. The clinical course and outcomes are discussed. Patient and Clinical Findings: 2 patients underwent uneventful cataract surgery and presented with recurrent anterior segment inflammation years after the surgery. In the first case, an 88-year-old man presented with granulomatous uveitis in the left eye 4 years after intracapsular cataract extraction and posterior chamber intraocular lens (CE/PC IOL) placement. In the second case, a 79-year-old woman presented with iritis 7 years after CE/PC IOL. Diagnosis, Intervention, and Outcomes: Both patients were treated for presumed idiopathic uveitis for years before the diagnosis of chronic endophthalmitis caused by Cutibacterium acnes. 1 case required endolaser photocoagulation to an infectious nidus. Conclusions: Chronic postoperative endophthalmitis can present many years after uneventful cataract surgery.
引言:据作者所知,这是白内障手术和慢性术后眼内炎诊断之间最长的两个报道时间。并对临床过程和结果进行了讨论。患者和临床表现:2例患者接受了白内障手术,术后几年出现复发性前段炎症。在第一例病例中,一名88岁男性在白内障囊内摘除和后房型人工晶状体(CE/PC IOL)置入术4年后出现左眼肉芽肿性葡萄膜炎。在第二个病例中,一名79岁的女性在CE/PC人工晶状体植入术后7年出现虹膜炎。诊断、干预和结果:在诊断为痤疮表皮杆菌引起的慢性眼内炎之前,两例患者均因推测为特发性葡萄膜炎接受了多年的治疗。1例需要激光光凝治疗感染病灶。结论:术后慢性眼内炎可在白内障手术后多年出现。
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引用次数: 1
Intraocular foreign body during cataract surgery 白内障手术中的眼内异物
Q4 Medicine Pub Date : 2022-08-31 DOI: 10.1097/j.jcro.0000000000000088
Alexander Thompson, R. Osher, L. Werner, S. Park, Samuel W. Wilkinson
Introduction: A large foreign body entered the anterior chamber through the infusion tubing during phacoemulsification. Patient and Clinical Findings: A 70-year-old woman presented for routine cataract extraction with implantation of a posterior chamber intraocular lens. During the phacoemulsification, a white fleck was captured on video entering the eye through the infusion tubing. Diagnosis, Intervention, and Outcomes: The fleck was removed immediately with a forceps through the main incision, and the surgery was completed. The fragment was preserved and sent for analysis. Scanning electron microscopy and energy-dispersive x-ray spectroscopy were used to determine its composition. Conclusions: The origin of the fragment was consistent with the spike used to pierce the bag containing the balanced salt solution.
导读:超声乳化术中,一大块异物通过输液管进入前房。患者和临床表现:一个70岁的妇女提出了常规白内障摘出植入后房型人工晶状体。在超声乳化过程中,视频捕捉到一个白色斑点通过输液管进入眼睛。诊断、干预和结果:立即用镊子从主切口取出斑点,完成手术。碎片被保存下来并送去分析。用扫描电子显微镜和能量色散x射线光谱法测定其成分。结论:碎片的来源与用于刺穿装有平衡盐溶液的袋子的刺头一致。
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引用次数: 0
Refractive shifts due to belantamab mafodotin–associated corneal toxicity 贝兰他单抗马夫多汀相关角膜毒性引起的屈光移位
Q4 Medicine Pub Date : 2022-07-22 DOI: 10.1097/j.jcro.0000000000000087
Aman Mittal, S. Garg
Introduction: This report describes a case of belantamab mafodotin–associated corneal toxicity. The patient presented with refractive changes, which has not been previously reported with this condition. Patient and Clinical Findings: A 58-year-old man with refractory multiple myeloma and myopia presented for screening before the initiation of belantamab mafodotin (belamaf or Blenrep, an antibody-drug conjugate [ADC] with known corneal toxicity). After 1 infusion, he returned complaining of loss of uncorrected near vision and was found to have bilateral keratopathy with microcyst-like epithelial changes (MECs) in the midperipheral cornea. Diagnosis, Intervention, and Outcomes: A hyperopic refractive error was seen with manifest refraction, and central flattening was seen on corneal topography. The patient was diagnosed with corneal epithelial toxicity secondary to belamaf. The medication was discontinued, and the MECs migrated centrally causing a refractive shift and eventually resolving. The patient was ultimately happy with his visual outcome because his uncorrected vision returned to baseline. Conclusions: Any vision changes in patients on ADCs should be carefully worked up, including with manifest refraction and appropriate testing, because they may indicate early ocular side effects that can be treated. This case introduces evidence of hyperopic and myopic changes directly correlating with slitlamp examination findings and imaging of a patient with belamaf-induced MECs.
本报告描述了一例贝兰他单抗马夫多汀相关的角膜毒性。患者表现为屈光改变,以前没有报道过这种情况。患者和临床发现:一名58岁男性难治性多发性骨髓瘤和近视患者在开始使用belantamab mafodotin (belamaf或Blenrep,一种已知角膜毒性的抗体-药物偶联物[ADC])之前进行了筛查。1次输注后,患者返回,主诉未矫正的近视力丧失,发现双侧角膜病变,中周角膜微囊样上皮改变(MECs)。诊断、干预和结果:见远视屈光不正伴明显屈光,角膜地形图见中央变平。患者被诊断为继发于belamaf的角膜上皮毒性。停药后,mec中心移位,导致屈光移位,最终消退。患者最终对视力结果感到满意,因为他未矫正的视力恢复到基线。结论:adc患者的任何视力变化都应仔细检查,包括明显的屈光和适当的检查,因为它们可能表明可以治疗的早期眼部副作用。本病例介绍了远视和近视变化的证据,这些变化与斜视灯检查结果和成像直接相关。
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引用次数: 0
Multimodal imaging findings in Purtscher-like retinopathy after retrobulbar anesthesia 球后麻醉后Purtscher样视网膜病变的多模式影像学表现
Q4 Medicine Pub Date : 2022-06-07 DOI: 10.1097/j.jcro.0000000000000084
Vasiliki Gliagias, A. Pandey, Isha Cheela
Introduction: This is a case of Purtscher-like retinopathy with an unusual etiology of retrobulbar anesthesia, evidenced by optical coherence tomography-angiography (OCT-A) images. Patient and Clinical Findings: After cataract surgery with a retrobulbar block, a 65-year-old woman experienced sudden dramatic visual reduction with superficial white retinal patches on fundus examination and corresponding capillary bed infarcts on fluorescein angiography and OCT-A. Diagnosis, Intervention, and Outcomes: Using advanced OCT-A, fluorescein angiography imaging, and fundus photography, the patient was diagnosed with Purtscher-like retinopathy. The patient was treated with topical steroids, nonsteroidal anti-inflammatory drops, and antibiotic drops, with gradual and nearly complete resolution of visual acuity. Conclusions: This case represents a rare but possible complication of retrobulbar anesthesia associated with cataract surgery. Despite dramatic changes on OCT-A, and in contrast to other reports with similar characteristic findings, our patient regained significant vision.
引言:这是一例具有球后麻醉异常病因的Purtscher样视网膜病变,光学相干断层扫描血管造影术(OCT-a)图像证明了这一点。患者和临床发现:一名65岁的女性在接受球后阻滞白内障手术后,在眼底检查中出现浅表白色视网膜斑块,在荧光素血管造影术和OCT-a检查中出现相应的毛细血管床梗死,视力突然急剧下降。诊断、干预和结果:使用先进的OCT-A、荧光素血管造影术和眼底照相术,患者被诊断为Purtscher样视网膜病变。患者接受了局部类固醇、非甾体抗炎药滴剂和抗生素滴剂的治疗,视力逐渐且几乎完全消退。结论:该病例是一种罕见但可能的白内障手术球后麻醉并发症。尽管OCT-A发生了巨大变化,与其他具有类似特征性发现的报告相比,我们的患者恢复了显著的视力。
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引用次数: 1
Intrascleral haptic needle fixation of 20+-year-old dislocated intraocular lenses using trailing-haptic-first modification 神经鞘内触觉针固定20岁以上脱位人工晶状体
Q4 Medicine Pub Date : 2022-06-02 DOI: 10.1097/j.jcro.0000000000000083
M. Kim, Dooho B. Kim
Introduction: Repositioning and scleral fixation of 20+-year-old dislocated intraocular lenses (IOLs) was performed using the trailing-haptic-first modification of the Yamane technique. Patient and Clinical Findings: 2 separate patients presented with late dislocation of their 3-piece IOLs, and the original surgeries were performed over 20 years ago. 1 patient had a Rezoom IOL and the other had an SI30 IOL. Diagnosis, Intervention, and Outcomes: The 2 patients underwent successful repositioning of the existing IOLs using the trailing-haptic-first modification of the Yamane technique. Both had good refractive outcomes without complication. Conclusions: To the authors' knowledge, these are the first cases reported of using 20+-year-old dislocated IOLs for successful intrascleral haptic needle fixation with the trailing-haptic-first modification of the Yamane technique. Surgeons should consider IOL repositioning with intrascleral haptic needle fixation instead of explantation for an easier and less-invasive approach.
介绍:采用触觉先行的Yamane技术对20岁以上脱位的人工晶状体(iol)进行复位和巩膜固定。患者和临床表现:2例独立患者表现为3块人工晶体的晚期脱位,最初的手术是在20多年前进行的。一例为Rezoom人工晶状体,另一例为SI30人工晶状体。诊断、干预和结果:2例患者使用Yamane技术的触觉先跟踪技术成功地重新定位了现有的iol。两例患者均有良好的屈光效果,无并发症。结论:据作者所知,这是第一例使用20岁以上的脱位人工晶状体,通过对Yamane技术进行触觉先追踪改良,成功实现神经鞘内触觉针固定的病例。外科医生应考虑用巩膜内触觉针固定人工晶状体,而不是用人工晶状体植入术,这是一种更容易、侵入性更小的方法。
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引用次数: 0
Correction of accommodative esotropia using hyperopic implantable collamer lenses 利用远视植入式晶体矫正调节性内斜视
Q4 Medicine Pub Date : 2022-05-25 DOI: 10.1097/j.jcro.0000000000000082
Eduardo Gonzalez-Lubcke, A. Navas, Enrique O. Graue-Hernández, A. Ramirez-Miranda, A. Gómez-Bastar
Introduction: To report a case of accommodative esotropia and high hyperopia managed with the Visian implantable collamer lens (ICL) phakic intraocular lens. Patient and Clinical Findings: The patient is a 21-year-old man with cycloplegic refraction of +7.50 −2.00 × 180 in both eyes. In addition, he presented a 30 prism diopters (PD) esotropia for both distance and near, which improved to 5 PD wearing his full cycloplegic prescription. Diagnosis, Intervention, and Outcomes: A patient with high hyperopia and accommodative esotropia with unchanged ocular alignment along with stable cycloplegic refraction for 2 years underwent bilateral ICL implantation. No intraoperative or postoperative complications were observed during the 12-month follow-up. The manifest refraction improved to +0.75 −0.75 × 180 postoperatively in the right eye and to +0.25 −0.50 × 180 in the left eye. No eyes lost lines of visual acuity. The esotropia improved to 5 PD at both distance and near without the need for spectacles. Conclusions: Hyperopic ICL implantation for accommodative esotropia may be considered a viable option to achieve spectacle independence and maintain proper eye alignment.
摘要:报告一例采用Visian人工晶状体(ICL)人工晶状体治疗调节性内斜视和高度远视的病例。患者和临床表现:患者男,21岁,双眼单眼屈光+7.50−2.00 × 180。此外,他提出了一个30棱镜屈光度(PD)内斜视远近,改善到5 PD戴着他的完整的单眼麻痹处方。诊断、干预和结果:一位高度远视和调节性内斜视患者,眼球排列不变,同时伴有稳定的单眼麻痹性屈光2年,接受了双侧ICL植入术。随访12个月,无术中、术后并发症发生。术后右眼明显屈光度为+0.75 ~ 0.75 × 180,左眼明显屈光度为+0.25 ~ 0.50 × 180。没有眼睛失去了视觉敏锐度。远视和近视内斜视均改善至5pd,无需配戴眼镜。结论:远视ICL植入术治疗调节性内斜视是一种实现眼镜独立性和保持眼睛正确排列的可行选择。
{"title":"Correction of accommodative esotropia using hyperopic implantable collamer lenses","authors":"Eduardo Gonzalez-Lubcke, A. Navas, Enrique O. Graue-Hernández, A. Ramirez-Miranda, A. Gómez-Bastar","doi":"10.1097/j.jcro.0000000000000082","DOIUrl":"https://doi.org/10.1097/j.jcro.0000000000000082","url":null,"abstract":"Introduction: To report a case of accommodative esotropia and high hyperopia managed with the Visian implantable collamer lens (ICL) phakic intraocular lens. Patient and Clinical Findings: The patient is a 21-year-old man with cycloplegic refraction of +7.50 −2.00 × 180 in both eyes. In addition, he presented a 30 prism diopters (PD) esotropia for both distance and near, which improved to 5 PD wearing his full cycloplegic prescription. Diagnosis, Intervention, and Outcomes: A patient with high hyperopia and accommodative esotropia with unchanged ocular alignment along with stable cycloplegic refraction for 2 years underwent bilateral ICL implantation. No intraoperative or postoperative complications were observed during the 12-month follow-up. The manifest refraction improved to +0.75 −0.75 × 180 postoperatively in the right eye and to +0.25 −0.50 × 180 in the left eye. No eyes lost lines of visual acuity. The esotropia improved to 5 PD at both distance and near without the need for spectacles. Conclusions: Hyperopic ICL implantation for accommodative esotropia may be considered a viable option to achieve spectacle independence and maintain proper eye alignment.","PeriodicalId":14598,"journal":{"name":"JCRS Online Case Reports","volume":"10 1","pages":"e00082"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42741740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical sterile infiltrates after corneal crosslinking 角膜交联后非典型无菌浸润
Q4 Medicine Pub Date : 2022-03-28 DOI: 10.1097/j.jcro.0000000000000081
T. Seiler, Karim Kozhaya, T. Seiler, S. Awwad
Introduction: 3 cases of atypical sterile opacifications during the early-postoperative phase after corneal crosslinking (CXL) have been described. Patient and Clinical Findings: On a routine follow-up 4 days after CXL, sterile anterior stromal opacifications were observed on slitlamp examination of patients with keratoconus (KC). Their presentations ranged from a crescentic opacification located at the margin of the irradiation zone at a depth of 270 μm (Case 1) to a peripheral well-delineated, disc-shaped opacification (Case 2) to disseminated multifocal infiltrates (Case 3). All reported eyes had completely healed epithelium with the onset of opacifications, more than 24 hours after CXL. After an interval of 6 months, only minor changes on slitlamp biomicroscopy were observed in each case, and optical coherence tomography was suggestive of a scar formation. Diagnosis, Intervention, and Outcome: The occurrence of these sterile infiltrates in KC eyes with thinnest pachymetry superior to 400 μm and their shape, location, and depth were remarkable. These infiltrates were labeled as atypical because they failed to respond to topical steroids and resulted in scar formation. Conclusions: A collection of atypical sterile anterior stromal infiltrates originating from the very early-postoperative course after accelerated or customized CXL have been reported.
引言:本文报道了3例角膜交联术后早期出现非典型无菌性混浊的病例。患者和临床发现:在CXL后4天的常规随访中,圆锥角膜(KC)患者的裂隙灯检查中观察到无菌前基质混浊。他们的表现从位于270μm深度照射区边缘的新月形混浊(病例1)到周围轮廓清晰的盘状混浊(病例2)再到播散性多灶浸润(病例3)。所有报告的眼睛在CXL后超过24小时,上皮完全愈合并出现混浊。间隔6个月后,在每个病例中,裂隙灯生物显微镜只观察到微小的变化,光学相干断层扫描提示瘢痕形成。诊断、干预和结果:这些无菌浸润在厚度最薄超过400μm的KC眼中发生,其形状、位置和深度都很显著。这些浸润被标记为非典型,因为它们对局部类固醇没有反应,并导致疤痕形成。结论:据报道,在加速或定制CXL后的术后早期过程中出现了非典型无菌前基质细胞浸润。
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引用次数: 0
Delayed intracapsular hematoma after use of iris retractor hooks 虹膜牵开钩术后迟发性囊内血肿
Q4 Medicine Pub Date : 2022-03-22 DOI: 10.1097/j.jcro.0000000000000080
Isabella V. Wagner, S. Dorairaj, Darby D. Miller, R. T. Ten Hulzen, M. Stewart
Introduction: To the author's knowledge, this is the first reported case of a delayed intracapsular hematoma after complex femtosecond laser–assisted cataract surgery (FLACS) and the use of iris retractor hooks for intraoperative floppy-iris syndrome. It is important that cataract surgeons be aware of this association. Patient and Clinical Findings: An 83-year-old man underwent FLACS with astigmatic keratotomy and intraocular lens implantation. Iris retractor hooks were used to counter intraoperative miosis. Hyphema, corneal edema, and subconjunctival hemorrhage were observed on postoperative day (POD) 1. The patient returned on POD 3 with further decrease in vision due to Descemet folds, advanced corneal edema, layered hyphema, and a dense intracapsular hematoma. Diagnosis, Intervention, and Outcomes: Minimal improvement of the hematoma occurred through 4 weeks, at which time the hematoma was drained with Nd:YAG laser posterior capsulotomy. The hematoma reabsorbed within 1 month with full recovery of vision. Conclusions: The iris retractor hooks in the setting of complex FLACS likely caused postoperative bleeding with accumulation of blood within the capsule. Nd:YAG laser posterior capsulotomy is an effective treatment option for nonclearing intracapsular hematoma.
简介:据作者所知,这是首例报道的复杂飞秒激光辅助白内障手术(FLACS)后迟发性囊内血肿的病例,术中使用虹膜牵开钩治疗虹膜软瘫综合征。白内障外科医生认识到这种联系是很重要的。患者和临床表现:一位83岁的男性接受了FLACS合并散光角膜切开术和人工晶状体植入术。虹膜牵开钩用于对抗术中瞳孔缩小。术后第1天观察到前房积血、角膜水肿和结膜下出血。患者复查POD 3后视力进一步下降,原因是视网膜褶皱、角膜水肿晚期、层状前房积血和致密囊内血肿。诊断,干预和结果:血肿在4周内出现轻微改善,此时使用Nd:YAG激光后囊膜切开术排出血肿。血肿在1个月内重新吸收,视力完全恢复。结论:在复杂FLACS情况下,虹膜牵开钩有可能引起术后出血和囊内积血。Nd:YAG激光后囊切开术是治疗囊内血肿不清的有效方法。
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引用次数: 0
Unilateral toxic anterior segment syndrome after immediate sequential bilateral phakic intraocular lens implantation 即刻顺序双侧晶状体人工晶状体植入术后单侧中毒性前段综合征
Q4 Medicine Pub Date : 2022-03-09 DOI: 10.1097/j.jcro.0000000000000072
K. Balparda, L. A. Silva-Quintero, Tatiana Herrera-Chalarca
Introduction: The requirement to perform immediate sequential bilateral cataract surgery (ISBCS) is controversial. Most surgeons who do not adhere to this approach cite the possibility of bilateral complications occurring. Patient and Clinical Findings: A 35-year-old woman underwent bilateral implantation of phakic intraocular lenses the same day. She complained of pain and significantly decreased quality of vision in her right eye 12 hours postoperatively and was immediately examined. Physical examination of the right eye showed significant corneal edema extending from limbus to limbus and a dilated fixed pupil unresponsive to light. Diagnosis, Intervention, and Outcomes: Physical examination showed toxic anterior segment syndrome ensued in one eye. The complication was timely managed, preventing further damage to the eye. The contralateral eye showed no signs of complication. Conclusions: This case highlights that, when performed with utmost care, protocols designed to avoid bilateral occurrence of complications in same-day surgeries can work in the real-world settings. This is further evidence that ISBCS may not pose an additional risk to patients.
引言:要求立即进行连续性双侧白内障手术(ISBCS)是有争议的。大多数不坚持这种方法的外科医生认为可能会出现双侧并发症。患者和临床发现:一名35岁的女性在同一天接受了双侧有晶状体人工晶状体植入术。术后12小时,她抱怨右眼疼痛,视力明显下降,并立即接受了检查。右眼的体检显示,角膜水肿从角膜缘延伸到角膜缘,瞳孔扩张,对光线没有反应。诊断、干预和结果:体格检查显示一只眼睛出现中毒性眼前节综合征。并发症得到了及时处理,防止了对眼睛的进一步损伤。对侧眼无并发症迹象。结论:本病例强调,当在极其谨慎的情况下进行手术时,旨在避免当天手术中双侧并发症发生的方案可以在现实世界中发挥作用。这进一步证明ISBCS可能不会对患者造成额外风险。
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引用次数: 0
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JCRS Online Case Reports
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