Pub Date : 2025-11-10DOI: 10.1177/21565333251395600
Nupur Mittal
{"title":"Health Disparities and Special Considerations for Adolescents and Young Adults (AYA) with Cancer.","authors":"Nupur Mittal","doi":"10.1177/21565333251395600","DOIUrl":"https://doi.org/10.1177/21565333251395600","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-10DOI: 10.1177/21565333251391612
Emily Haines, John M Salsman, Carly Meredith, Stephanie C Bunch, Stacy Sanford
{"title":"Screening and Needs Assessments in Adolescent and Young Adult Oncology.","authors":"Emily Haines, John M Salsman, Carly Meredith, Stephanie C Bunch, Stacy Sanford","doi":"10.1177/21565333251391612","DOIUrl":"https://doi.org/10.1177/21565333251391612","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145549538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Aim: Adolescent and young adult (AYA) patients who require pancreatectomy are rare. There are few reports concerning the characteristics of AYA patients undergoing pancreatectomy for malignant tumors. This study aimed to clarify the characteristics and outcomes of AYA patients who had undergone pancreatectomy. Methods: AYA patients (age 15-35 years) who underwent pancreatectomy at our institution between 1995 and 2018 were included in this study. The diagnosis, operative procedure, complications, mortality, and survival were retrospectively analyzed. Results: Forty-seven patients underwent pancreatectomy (median age 29 years; range, 16-35 years). The diagnoses were solid-pseudopapillary neoplasm (SPN; n = 21 [44.6%]), neuroendocrine neoplasm (NEN; n = 12 [25.5%]), adenocarcinoma (n = 5 [10.6%]), and others (n = 9 [19.1%]). The surgical procedures included pancreatoduodenectomy (PD; n = 17 [36.1%]), distal pancreatectomy (DP; n = 18 [38.2%]), middle pancreatectomy (n = 8 [17.0%]), and tumor enucleation (n = 4 [8.5%]). The most common postoperative complication was pancreatic fistula (POPF) (n = 29 [61.7%]). Hemorrhage was noted in one case, but the surgical mortality rate was 0%. Long-term complications included four cases of pancreatitis, three cases of diabetes, two cases of bowel obstruction, and one case of cholangitis. The 5-year recurrence-free-survival (RFS) and overall-survival (OS) rates in patients with SPN/NEN/others were 91.8% and 97.5%, respectively. In contrast, the 5-year RFS and OS rates in patients with adenocarcinoma were 53.3% and 80.0%, respectively. Conclusion: Most AYA patients who underwent pancreatectomy had low-grade malignancies and showed a favorable survival. Although POPF and pancreatitis frequently occur, radical surgery-even major pancreatectomy such as PD and DP-is feasible and effective in AYA patients with malignant tumors.
背景和目的：青少年和青壮年（AYA）患者需要胰腺切除术是罕见的。关于恶性肿瘤行胰腺切除术的AYA患者的特点报道很少。本研究旨在阐明行胰腺切除术的AYA患者的特点和预后。方法：本研究纳入1995年至2018年在我院行胰腺切除术的AYA患者（15-35岁）。回顾性分析诊断、手术方式、并发症、死亡率和生存率。结果：47例患者行胰腺切除术（中位年龄29岁，范围16-35岁）。诊断为实性假乳头状瘤（SPN; n = 21[44.6%]）、神经内分泌瘤（NEN; n = 12[25.5%]）、腺癌（n = 5[10.6%]）和其他（n = 9[19.1%]）。手术包括胰十二指肠切除术（PD, n = 17例[36.1%]）、远端胰切除术（DP, n = 18例[38.2%]）、中端胰切除术（n = 8例[17.0%]）、肿瘤去核术（n = 4例[8.5%]）。最常见的术后并发症是胰瘘（POPF） （n = 29[61.7%]）。1例出血，但手术死亡率为0%。长期并发症包括胰腺炎4例，糖尿病3例，肠梗阻2例，胆管炎1例。SPN/NEN/其他患者的5年无复发生存率（RFS）和总生存率（OS）分别为91.8%和97.5%。相比之下，腺癌患者的5年RFS和OS分别为53.3%和80.0%。结论：大多数行胰腺切除术的AYA患者为低级别恶性肿瘤，生存率较高。虽然经常发生POPF和胰腺炎，但根治性手术-甚至PD和dp等大胰腺切除术-对于AYA恶性肿瘤患者是可行和有效的。
{"title":"Clinical Characteristics of Adolescent and Young Adult Patients Undergoing Pancreatectomy for Malignant Tumors: A 20-Year Single Institution Experience.","authors":"Naonori Kawakubo, Minoru Esaki, Satoshi Nara, Akinori Miyata, Takahiro Mizui, Ryosuke Umino, Junkichi Takemoto, Tomoro Hishiki, Akihiro Yoneda","doi":"10.1177/21565333251394590","DOIUrl":"https://doi.org/10.1177/21565333251394590","url":null,"abstract":"<p><p><b><i>Background and Aim:</i></b> Adolescent and young adult (AYA) patients who require pancreatectomy are rare. There are few reports concerning the characteristics of AYA patients undergoing pancreatectomy for malignant tumors. This study aimed to clarify the characteristics and outcomes of AYA patients who had undergone pancreatectomy. <b><i>Methods:</i></b> AYA patients (age 15-35 years) who underwent pancreatectomy at our institution between 1995 and 2018 were included in this study. The diagnosis, operative procedure, complications, mortality, and survival were retrospectively analyzed. <b><i>Results:</i></b> Forty-seven patients underwent pancreatectomy (median age 29 years; range, 16-35 years). The diagnoses were solid-pseudopapillary neoplasm (SPN; <i>n</i> = 21 [44.6%]), neuroendocrine neoplasm (NEN; <i>n</i> = 12 [25.5%]), adenocarcinoma (<i>n</i> = 5 [10.6%]), and others (<i>n</i> = 9 [19.1%]). The surgical procedures included pancreatoduodenectomy (PD; <i>n</i> = 17 [36.1%]), distal pancreatectomy (DP; <i>n</i> = 18 [38.2%]), middle pancreatectomy (<i>n</i> = 8 [17.0%]), and tumor enucleation (<i>n</i> = 4 [8.5%]). The most common postoperative complication was pancreatic fistula (POPF) (<i>n</i> = 29 [61.7%]). Hemorrhage was noted in one case, but the surgical mortality rate was 0%. Long-term complications included four cases of pancreatitis, three cases of diabetes, two cases of bowel obstruction, and one case of cholangitis. The 5-year recurrence-free-survival (RFS) and overall-survival (OS) rates in patients with SPN/NEN/others were 91.8% and 97.5%, respectively. In contrast, the 5-year RFS and OS rates in patients with adenocarcinoma were 53.3% and 80.0%, respectively. <b><i>Conclusion:</i></b> Most AYA patients who underwent pancreatectomy had low-grade malignancies and showed a favorable survival. Although POPF and pancreatitis frequently occur, radical surgery-even major pancreatectomy such as PD and DP-is feasible and effective in AYA patients with malignant tumors.</p>","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-07DOI: 10.1177/21565333251393838
Deena R Levine, Angela Steineck, R Elyse Heidelberg, Holly Spraker-Perlman
{"title":"Palliative Care in Adolescent and Young Adult Oncology: Guidelines and Resources for Care.","authors":"Deena R Levine, Angela Steineck, R Elyse Heidelberg, Holly Spraker-Perlman","doi":"10.1177/21565333251393838","DOIUrl":"https://doi.org/10.1177/21565333251393838","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Working in This Field and Living in This Field: The Importance of Cancer Survivors in the Professional Setting.","authors":"Alique Topalian, Elissa Baldwin, Veronika Panagiotou","doi":"10.1177/21565333251394601","DOIUrl":"https://doi.org/10.1177/21565333251394601","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145471152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1177/21565333251393836
Tiffany Blair, Sarah Daniels
{"title":"Awareness and Education Needs in Adolescent and Young Adult Oncology.","authors":"Tiffany Blair, Sarah Daniels","doi":"10.1177/21565333251393836","DOIUrl":"https://doi.org/10.1177/21565333251393836","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145444850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-28DOI: 10.1177/21565333251393030
Marie Barnett, Tori Hinton, Sarah Daniels, Cristina Pozo-Kaderman, Heather Haluska, Mandy Little, Lori Wiener
{"title":"Recommendations for Psychosocial Care in Adolescent and Young Adult Oncology.","authors":"Marie Barnett, Tori Hinton, Sarah Daniels, Cristina Pozo-Kaderman, Heather Haluska, Mandy Little, Lori Wiener","doi":"10.1177/21565333251393030","DOIUrl":"https://doi.org/10.1177/21565333251393030","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145389781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-28DOI: 10.1177/21565333251393029
Meghan E McGrady, Rachel Tillery Webster, Julie A Wolfson
{"title":"Treatment Adherence and Self-Management in Adolescent and Young Adult Oncology.","authors":"Meghan E McGrady, Rachel Tillery Webster, Julie A Wolfson","doi":"10.1177/21565333251393029","DOIUrl":"https://doi.org/10.1177/21565333251393029","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145389811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-24DOI: 10.1177/21565333251392237
Anao Zhang, Stephanie Dixon, Victoria W Willard, Archie Bleyer
{"title":"Advancing Research for Adolescents and Young Adults Cancer: A Position Statement.","authors":"Anao Zhang, Stephanie Dixon, Victoria W Willard, Archie Bleyer","doi":"10.1177/21565333251392237","DOIUrl":"https://doi.org/10.1177/21565333251392237","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145367860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-23DOI: 10.1177/21565333251392393
Sarah Daniels, Michael Bishop, Valerie Crabtree
{"title":"Understanding Guidelines and Navigating Barriers to Comprehensive Oncology Care: A Multidisciplinary Meeting to Review of Evidence-Based Practices and Resources for Adolescent and Young Adults.","authors":"Sarah Daniels, Michael Bishop, Valerie Crabtree","doi":"10.1177/21565333251392393","DOIUrl":"https://doi.org/10.1177/21565333251392393","url":null,"abstract":"","PeriodicalId":14769,"journal":{"name":"Journal of adolescent and young adult oncology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145354777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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