首页 > 最新文献

JDR Clinical & Translational Research最新文献

英文 中文
Oral Disease and Atherosclerosis May Be Associated with Overlapping Metabolic Pathways. 口腔疾病和动脉粥样硬化可能与重叠的代谢途径有关。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-09 DOI: 10.1177/23800844241280383
M Bezamat, A Saeed, C McKennan, J Duan, R Zhou, D J Baxter, L Liu, L de Las Fuentes, B Foxman, J R Shaffer, D W McNeil, M L Marazita, S E Reis
<p><strong>Objectives: </strong>Dental caries and periodontitis are among the most prevalent chronic diseases worldwide and have been associated with atherosclerotic cardiovascular diseases (ASCVD). This study aimed to determine (1) the independent associations between subclinical ASCVD markers (carotid intima media thickness [CIMT] and coronary artery calcification [CAC]) and quantitative indices of oral disease including the decayed, missing, and filled teeth (DMFT) index, gingivitis parameters, periodontal status, and number of teeth lost and (2) the extent to which metabolites altered in individuals with oral disease overlapped with those altered in individuals with ASCVD.</p><p><strong>Methods: </strong>We used data from 552 participants recruited through the Dental Strategies Concentrating on Risk Evaluation project. Oral examinations were conducted, and CIMT and CAC were measured. Multiple linear regression models were constructed with CIMT and CAC as dependent variables in the epidemiologic analysis. In the metabolomic analysis, logistic or linear regression was used to test 1,228 metabolites for association with each phenotype adjusted for age, sex, race, blood pressure, smoking, diabetes, cholesterol, high-sensitivity C-reactive protein, and interleukin-6.</p><p><strong>Results: </strong>None of the oral disease markers were significant predictors of ASCVD markers in the fully adjusted models. However, critical lipid and lipid-signaling pathway metabolites were significantly associated with gingivitis, periodontitis, and DMFT: the lysophospholipid pathway (odds ratio [OR] = 2.29, false discovery rate [FDR]-adjusted <i>P</i> = 0.038) and arachidonate with gingivitis (OR = 2.35, FDR-adjusted <i>P</i> = 0.015), the sphingolipid metabolism pathway with periodontitis (OR = 2.09, FDR-adjusted <i>P</i> = 0.029), and borderline associations between plasmalogen and lysophospholipid pathways and DMFT (P = 0.055). Further, the same metabolite from the sphingolipid metabolism pathway, sphingomyelin (d17:1/14:0, d16:1/15:0), was inversely associated with both CIMT (β = -0.14, FDR-adjusted P = 0.014) and gingivitis (OR = 0.04, FDR-adjusted <i>P</i> = 0.033).</p><p><strong>Conclusions: </strong>The discovery of a common sphingomyelin metabolite in both disease processes is a novel finding suggesting that gingivitis and periodontitis may be associated with some overlapping metabolic pathways associated with ASCVD and indicating potential shared mechanisms among these diseases.</p><p><strong>Knowledge transfer statement: </strong>The same metabolites may be altered in atherosclerosis and oral disease. Specifically, a common sphingomyelin metabolite was inversely associated with gingivitis and carotid intima media thickness, a subclinical marker of atherosclerotic cardiovascular disease. These findings can provide valuable insights for future mechanistic studies to establish potential causal relationships, with the hope of influencing disease prevention
目的:龋齿和牙周炎是全球最普遍的慢性疾病之一,与动脉粥样硬化性心血管疾病(ASCVD)有关。本研究旨在确定:(1) 亚临床 ASCVD 标志物(颈动脉内膜厚度 [CIMT] 和冠状动脉钙化 [CAC])与口腔疾病定量指标(包括蛀牙、缺牙和补牙 (DMFT) 指数、牙龈炎参数、牙周状况和掉牙数量)之间的独立关联;(2) 口腔疾病患者体内代谢物的改变与 ASCVD 患者体内代谢物的改变之间的重叠程度:我们使用了通过 "专注于风险评估的牙科策略 "项目招募的 552 名参与者的数据。我们进行了口腔检查,并测量了 CIMT 和 CAC。在流行病学分析中,以 CIMT 和 CAC 为因变量建立了多元线性回归模型。在代谢组学分析中,使用逻辑或线性回归来检验 1,228 种代谢物与每种表型的相关性,并对年龄、性别、种族、血压、吸烟、糖尿病、胆固醇、高敏 C 反应蛋白和白细胞介素-6 进行了调整:结果:在完全调整模型中,没有一个口腔疾病指标能显著预测急性心血管疾病指标。然而,关键的脂质和脂质信号通路代谢物与牙龈炎、牙周炎和 DMFT 有显著相关性:溶血磷脂通路(比值比 [OR] = 2.29,假发现率 [FDR] 调整后 P = 0.038),花生四烯酸与牙龈炎(OR = 2.35,FDR 调整后 P = 0.015),鞘脂代谢途径与牙周炎(OR = 2.09,FDR 调整后 P = 0.029),质原和溶血磷脂途径与 DMFT 之间存在边缘关联(P = 0.055)。此外,鞘磷脂代谢途径中的同一种代谢物--鞘磷脂(d17:1/14:0,d16:1/15:0)与CIMT(β = -0.14,FDR调整后P = 0.014)和牙龈炎(OR = 0.04,FDR调整后P = 0.033)呈反相关:结论:在这两种疾病过程中发现一种共同的鞘磷脂代谢物是一项新发现,表明牙龈炎和牙周炎可能与ASCVD相关的某些代谢途径重叠,并表明这些疾病之间可能存在共同的机制:动脉粥样硬化和口腔疾病可能会改变相同的代谢物。具体来说,一种常见的鞘磷脂代谢物与牙龈炎和颈动脉内膜厚度成反比,而颈动脉内膜厚度是动脉粥样硬化性心血管疾病的亚临床标志物。这些发现可为今后的机理研究提供宝贵的见解,以确定潜在的因果关系,从而对疾病预防和有针对性的早期治疗产生影响。
{"title":"Oral Disease and Atherosclerosis May Be Associated with Overlapping Metabolic Pathways.","authors":"M Bezamat, A Saeed, C McKennan, J Duan, R Zhou, D J Baxter, L Liu, L de Las Fuentes, B Foxman, J R Shaffer, D W McNeil, M L Marazita, S E Reis","doi":"10.1177/23800844241280383","DOIUrl":"10.1177/23800844241280383","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;Dental caries and periodontitis are among the most prevalent chronic diseases worldwide and have been associated with atherosclerotic cardiovascular diseases (ASCVD). This study aimed to determine (1) the independent associations between subclinical ASCVD markers (carotid intima media thickness [CIMT] and coronary artery calcification [CAC]) and quantitative indices of oral disease including the decayed, missing, and filled teeth (DMFT) index, gingivitis parameters, periodontal status, and number of teeth lost and (2) the extent to which metabolites altered in individuals with oral disease overlapped with those altered in individuals with ASCVD.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We used data from 552 participants recruited through the Dental Strategies Concentrating on Risk Evaluation project. Oral examinations were conducted, and CIMT and CAC were measured. Multiple linear regression models were constructed with CIMT and CAC as dependent variables in the epidemiologic analysis. In the metabolomic analysis, logistic or linear regression was used to test 1,228 metabolites for association with each phenotype adjusted for age, sex, race, blood pressure, smoking, diabetes, cholesterol, high-sensitivity C-reactive protein, and interleukin-6.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;None of the oral disease markers were significant predictors of ASCVD markers in the fully adjusted models. However, critical lipid and lipid-signaling pathway metabolites were significantly associated with gingivitis, periodontitis, and DMFT: the lysophospholipid pathway (odds ratio [OR] = 2.29, false discovery rate [FDR]-adjusted &lt;i&gt;P&lt;/i&gt; = 0.038) and arachidonate with gingivitis (OR = 2.35, FDR-adjusted &lt;i&gt;P&lt;/i&gt; = 0.015), the sphingolipid metabolism pathway with periodontitis (OR = 2.09, FDR-adjusted &lt;i&gt;P&lt;/i&gt; = 0.029), and borderline associations between plasmalogen and lysophospholipid pathways and DMFT (P = 0.055). Further, the same metabolite from the sphingolipid metabolism pathway, sphingomyelin (d17:1/14:0, d16:1/15:0), was inversely associated with both CIMT (β = -0.14, FDR-adjusted P = 0.014) and gingivitis (OR = 0.04, FDR-adjusted &lt;i&gt;P&lt;/i&gt; = 0.033).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The discovery of a common sphingomyelin metabolite in both disease processes is a novel finding suggesting that gingivitis and periodontitis may be associated with some overlapping metabolic pathways associated with ASCVD and indicating potential shared mechanisms among these diseases.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Knowledge transfer statement: &lt;/strong&gt;The same metabolites may be altered in atherosclerosis and oral disease. Specifically, a common sphingomyelin metabolite was inversely associated with gingivitis and carotid intima media thickness, a subclinical marker of atherosclerotic cardiovascular disease. These findings can provide valuable insights for future mechanistic studies to establish potential causal relationships, with the hope of influencing disease prevention ","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":" ","pages":"23800844241280383"},"PeriodicalIF":2.2,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of Severe Early Childhood Caries over Time in Low-Income Preschoolers. 低收入学龄前儿童随着时间推移患严重幼儿龋齿的风险。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-02 DOI: 10.1177/23800844241279266
Y C Chou, F S Cheng, S H Weng, H Y Hu

Introduction: Early childhood caries (ECC), and the progression to severe ECC (S-ECC), is a serious oral health issue, leading to acute pain, sepsis, tooth loss, and compromised quality of life. Although the association between sociodemographic factors and ECC has been widely discussed, it remains unclear whether the same association exists between inequality and S-ECC.

Objectives: To investigate the impact of low income on the oral health of preschool children and explore any additional risk factors for developing ECC and S-ECC during follow-up.

Methods: The study used Taipei Child Development Screening Program data from 2014 to 2019. It included children aged 3 to 5 y who had more than 2 oral exams and completed baseline oral health questionnaires. Low-income children were matched 1:4 with controls by age and gender. Evaluation of ECC and S-ECC used the dmft index during follow-up exams. Generalized estimating equations (GEEs) assessed the impact of household income on ECC and S-ECC risk over time.

Results: Of the 895 participants, 179 were from low-income households. We revealed a significantly higher risk of developing S-ECC (adjusted odds ratio [aOR] 1.99; 95% confidence interval [CI] 1.25-3.17) in children from low-income households, with no significantly increased of risk of developing ECC. Children who consumed sugary beverages >4 times per week showed elevated risks of developing both ECC (aOR 1.77; 95% CI 1.07-2.94) and S-ECC (aOR 1.89; 95% CI 1.13-3.17). Protective factors included children with mothers with a college education (S-ECC: aOR 0.50; 95% CI 0.32-0.79).

Conclusion: Children from low-income households have a significant risk of developing S-ECC compared with children from non-low-income households during follow-up. Factors contributing to this risk include lower maternal education, poor maternal oral health, and increased consumption of sugar-sweetened beverages. Policymakers should develop health measures to reduce the prevalence of ECC and S-ECC in children from low-income households whose mothers have lower educational levels and poor oral health.

Knowledge transfer statement: The results of this study highlight the significant S-ECC risk among preschool children from low-income households in Taipei, with other risk factors including higher consumption of sugar-sweetened beverages, lower maternal education, and poor maternal oral health. Policymakers can use our findings to develop targeted policy and behavioral interventions to reduce S-ECC in vulnerable populations.

导言:儿童早期龋齿(ECC)以及发展为严重龋齿(S-ECC)是一个严重的口腔健康问题,可导致急性疼痛、败血症、牙齿脱落和生活质量下降。尽管社会人口因素与 ECC 之间的关联已被广泛讨论,但不平等与 S-ECC 之间是否存在同样的关联仍不清楚:调查低收入对学龄前儿童口腔健康的影响,并探讨在随访过程中出现 ECC 和 S-ECC 的其他风险因素:研究使用了2014年至2019年的台北儿童发育筛查计划数据。研究对象包括接受过两次以上口腔检查并完成基线口腔健康问卷调查的3至5岁儿童。低收入儿童与对照组儿童按年龄和性别1:4配对。在随访检查中使用 dmft 指数对 ECC 和 S-ECC 进行评估。广义估计方程(GEEs)评估了家庭收入随着时间的推移对ECC和S-ECC风险的影响:结果:在 895 名参与者中,有 179 人来自低收入家庭。我们发现,低收入家庭的儿童患 S-ECC 的风险明显更高(调整赔率比 [aOR] 1.99;95% 置信区间 [CI] 1.25-3.17),而患 ECC 的风险没有明显增加。每周饮用含糖饮料超过 4 次的儿童患 ECC(aOR 1.77;95% CI 1.07-2.94)和 S-ECC (aOR 1.89;95% CI 1.13-3.17)的风险均有所升高。保护因素包括母亲受过大学教育的儿童(S-ECC:aOR 0.50;95% CI 0.32-0.79):结论:与非低收入家庭的儿童相比,低收入家庭的儿童在随访期间患 S-ECC 的风险很高。导致这一风险的因素包括母亲教育程度较低、母亲口腔健康状况较差以及含糖饮料的消费量增加。政策制定者应制定保健措施,降低低收入家庭中母亲受教育程度较低且口腔健康状况较差的儿童的幼儿急慢性口腔疾病和急性幼儿急慢性口腔疾病发病率:本研究的结果突出表明,在台北低收入家庭的学龄前儿童中,S-ECC 风险很大,其他风险因素包括较高的含糖饮料消费量、较低的母亲教育水平和较差的母亲口腔健康状况。政策制定者可以利用我们的研究结果制定有针对性的政策和行为干预措施,以降低弱势群体的 S-ECC 风险。
{"title":"Risk of Severe Early Childhood Caries over Time in Low-Income Preschoolers.","authors":"Y C Chou, F S Cheng, S H Weng, H Y Hu","doi":"10.1177/23800844241279266","DOIUrl":"https://doi.org/10.1177/23800844241279266","url":null,"abstract":"<p><strong>Introduction: </strong>Early childhood caries (ECC), and the progression to severe ECC (S-ECC), is a serious oral health issue, leading to acute pain, sepsis, tooth loss, and compromised quality of life. Although the association between sociodemographic factors and ECC has been widely discussed, it remains unclear whether the same association exists between inequality and S-ECC.</p><p><strong>Objectives: </strong>To investigate the impact of low income on the oral health of preschool children and explore any additional risk factors for developing ECC and S-ECC during follow-up.</p><p><strong>Methods: </strong>The study used Taipei Child Development Screening Program data from 2014 to 2019. It included children aged 3 to 5 y who had more than 2 oral exams and completed baseline oral health questionnaires. Low-income children were matched 1:4 with controls by age and gender. Evaluation of ECC and S-ECC used the dmft index during follow-up exams. Generalized estimating equations (GEEs) assessed the impact of household income on ECC and S-ECC risk over time.</p><p><strong>Results: </strong>Of the 895 participants, 179 were from low-income households. We revealed a significantly higher risk of developing S-ECC (adjusted odds ratio [aOR] 1.99; 95% confidence interval [CI] 1.25-3.17) in children from low-income households, with no significantly increased of risk of developing ECC. Children who consumed sugary beverages >4 times per week showed elevated risks of developing both ECC (aOR 1.77; 95% CI 1.07-2.94) and S-ECC (aOR 1.89; 95% CI 1.13-3.17). Protective factors included children with mothers with a college education (S-ECC: aOR 0.50; 95% CI 0.32-0.79).</p><p><strong>Conclusion: </strong>Children from low-income households have a significant risk of developing S-ECC compared with children from non-low-income households during follow-up. Factors contributing to this risk include lower maternal education, poor maternal oral health, and increased consumption of sugar-sweetened beverages. Policymakers should develop health measures to reduce the prevalence of ECC and S-ECC in children from low-income households whose mothers have lower educational levels and poor oral health.</p><p><strong>Knowledge transfer statement: </strong>The results of this study highlight the significant S-ECC risk among preschool children from low-income households in Taipei, with other risk factors including higher consumption of sugar-sweetened beverages, lower maternal education, and poor maternal oral health. Policymakers can use our findings to develop targeted policy and behavioral interventions to reduce S-ECC in vulnerable populations.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":" ","pages":"23800844241279266"},"PeriodicalIF":2.2,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periodontitis and Metabolic Control of Adults with Type 1 Diabetes. 1 型糖尿病成人的牙周炎和代谢控制。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1177/23800844241273858
A Jeftha, A Suliman, M Conradie-Smit, F Kimmie-Dhansay

Introduction: Periodontitis has been reported with increased incidence and prevalence in patients with diabetes mellitus (DM). Noncommunicable diseases burden the South African public health system, and there are no data reporting on this relationship in this population. This is required to inform management protocols in type 1 diabetes mellitus (T1DM), which currently exclude the importance of periodontal treatment.

Objectives: The aim of this study was to determine whether there was an association between periodontitis and the glycemic control of adult patients with T1DM at a tertiary institution in South Africa.

Methods: A cross-sectional study was conducted on adults diagnosed with T1DM. Bleeding on probing, periodontal pocket depth, and radiographical bone loss were assessed and the periodontal status of the patient was compared to their glycemic control, measured by HbA1c. An HbA1c level of ≤7% was considered to indicate adequate glycemic control.

Results: There were 120 adult participants, of whom 61.7% (74) were female and 38.3% (46) were male. The majority were nonsmokers and younger than 44 y. There were 78 (65%) participants with uncontrolled blood glucose and 42 (35%) with good control (HbA1c ≤ 7%). The median HbA1c level was 8.75 (range, 6.1 to 12.2). Most participants (94%) had periodontitis, and 97% of them had uncontrolled blood glucose.

Conclusion: There was an association between percentage bleeding score (P < 0.001) and metabolic control in adults with T1DM treated at a tertiary hospital in Cape Town, South Africa. Periodontitis severity as described by staging was not associated with T1DM in this sample. The high prevalence of periodontitis in this sample (94%) highlights the need for periodontal management to form a part of holistic patient care in patients with T1DM in this setting.

Knowledge transfer statement: The study results highlight the role of periodontitis severity and gingival bleeding scores on the metabolic control of adults with T1DM and thus emphasizes the importance of periodontal care in whole-person health in this patient population.

导言:据报道,牙周炎在糖尿病(DM)患者中的发病率和流行率都有所上升。非传染性疾病给南非的公共卫生系统带来了沉重负担,但目前还没有关于这一人群中牙周炎与糖尿病关系的数据报告。目前,1 型糖尿病(T1DM)的管理方案不包括牙周治疗的重要性,因此需要这方面的信息:本研究旨在确定牙周炎与南非一家三级医疗机构的 T1DM 成年患者的血糖控制之间是否存在关联:方法:对确诊为 T1DM 的成人患者进行横断面研究。对探诊出血、牙周袋深度和放射性骨质流失进行了评估,并将患者的牙周状况与他们的血糖控制(以 HbA1c 为测量指标)进行了比较。HbA1c水平≤7%被视为血糖控制良好:共有 120 名成年参与者,其中女性占 61.7%(74 人),男性占 38.3%(46 人)。78人(65%)血糖未得到控制,42人(35%)血糖控制良好(HbA1c ≤ 7%)。HbA1c 中位数为 8.75(范围为 6.1 至 12.2)。大多数参与者(94%)患有牙周炎,其中 97% 的人血糖未得到控制:结论:在南非开普敦一家三级医院接受治疗的 T1DM 成人患者中,出血评分百分比(P < 0.001)与代谢控制之间存在关联。在该样本中,根据分期描述的牙周炎严重程度与 T1DM 无关。该样本中牙周炎的发病率很高(94%),这凸显了在这种情况下对 T1DM 患者进行牙周管理,使之成为患者整体护理的一部分的必要性:研究结果凸显了牙周炎严重程度和牙龈出血评分对成人 T1DM 患者代谢控制的作用,从而强调了牙周护理在该患者群体全人健康中的重要性。
{"title":"Periodontitis and Metabolic Control of Adults with Type 1 Diabetes.","authors":"A Jeftha, A Suliman, M Conradie-Smit, F Kimmie-Dhansay","doi":"10.1177/23800844241273858","DOIUrl":"10.1177/23800844241273858","url":null,"abstract":"<p><strong>Introduction: </strong>Periodontitis has been reported with increased incidence and prevalence in patients with diabetes mellitus (DM). Noncommunicable diseases burden the South African public health system, and there are no data reporting on this relationship in this population. This is required to inform management protocols in type 1 diabetes mellitus (T1DM), which currently exclude the importance of periodontal treatment.</p><p><strong>Objectives: </strong>The aim of this study was to determine whether there was an association between periodontitis and the glycemic control of adult patients with T1DM at a tertiary institution in South Africa.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on adults diagnosed with T1DM. Bleeding on probing, periodontal pocket depth, and radiographical bone loss were assessed and the periodontal status of the patient was compared to their glycemic control, measured by HbA1c. An HbA1c level of ≤7% was considered to indicate adequate glycemic control.</p><p><strong>Results: </strong>There were 120 adult participants, of whom 61.7% (74) were female and 38.3% (46) were male. The majority were nonsmokers and younger than 44 y. There were 78 (65%) participants with uncontrolled blood glucose and 42 (35%) with good control (HbA1c ≤ 7%). The median HbA1c level was 8.75 (range, 6.1 to 12.2). Most participants (94%) had periodontitis, and 97% of them had uncontrolled blood glucose.</p><p><strong>Conclusion: </strong>There was an association between percentage bleeding score (P < 0.001) and metabolic control in adults with T1DM treated at a tertiary hospital in Cape Town, South Africa. Periodontitis severity as described by staging was not associated with T1DM in this sample. The high prevalence of periodontitis in this sample (94%) highlights the need for periodontal management to form a part of holistic patient care in patients with T1DM in this setting.</p><p><strong>Knowledge transfer statement: </strong>The study results highlight the role of periodontitis severity and gingival bleeding scores on the metabolic control of adults with T1DM and thus emphasizes the importance of periodontal care in whole-person health in this patient population.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":"9 1_suppl","pages":"6S-12S"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward a Comprehensive Model of Medical-Dental-Behavioral Integration. 迈向医疗-牙科-行为一体化的综合模式。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1177/23800844241273836
D W McNeil, D B Pereira, O S Ensz, K Lukose, G Harrell, D B Feller

Introduction: Existing models of medical-dental integration, as well as those from behavioral health care integrated with primary medical treatment, provide a basis for a truly synthesized and expanded model incorporating medical, dental, and behavioral components. Such a comprehensive model allows for collaborative health care serving patients seamlessly without disciplinary silos, promoting optimal whole-person health. This innovative approach is consistent with recent developments in the behavioral and social oral health sciences that include an imperative for their full inclusion in dental health care, research, and education.

Methods: Existing models of medical-dental integration are described, along with current models from integrated primary medical and behavioral health care. Using these existing approaches as a basis, a new multilevel model is proposed to include social and cultural determinants of health.

Results: Contemporary approaches to providing health care across disciplines include referral to a geographically separate entity, co-location of services, and integrated, side-by-side care. Integration of electronic health records and interoperability are necessary (but not sufficient) factors that affect transdisciplinary health care. Effective communication among health care providers and the need for interprofessional education, comprehensive training, and ongoing cross-disciplinary consultation also are noted as crucial factors in truly collaborative care. Evidence for existing models varies greatly depending on the target population and type of services provided.

Conclusions: A fully integrated, transdisciplinary model of health care is possible, theoretically and practically. Combining aspects of extant integrated models and extending them provides opportunity for a greater focus on systemic factors and more emphasis on prevention. Consistent with this new model, medical and dental home concepts can be expanded to that of a person-centered health care home that includes interprofessional practice. This transdisciplinary approach contributes to greater health equity given the multilevel approach. Multidirectional integration of diverse disciplines representing the various realms of medicine, dentistry, and behavioral health care is essential for optimal health of all.

Knowledge transfer statement: This article can be used by clinicians, scientists, administrators, and policy makers in developing and implementing integrated systems of care that provide for patients' medical, dental, and behavioral health needs.

导言:现有的医疗与牙科相结合的模式,以及行为健康护理与初级医疗相结合的模式,为真正的综合和扩展模式提供了基础,其中包含了医疗、牙科和行为等组成部分。这种综合模式可以让协作式医疗保健在没有学科孤岛的情况下为患者提供无缝服务,促进最佳的全人健康。这种创新方法与行为和社会口腔健康科学的最新发展是一致的,其中包括将其全面纳入牙科保健、研究和教育的必要性:方法:描述了现有的医学-口腔医学结合模式,以及目前的初级医疗和行为健康综合护理模式。以这些现有的方法为基础,提出了一个新的多层次模式,将健康的社会和文化决定因素纳入其中:结果:跨学科提供医疗保健服务的现代方法包括转诊到地理上独立的实体、共用服务地点以及综合并肩护理。电子健康记录的整合和互操作性是影响跨学科医疗保健的必要(但不充分)因素。医疗服务提供者之间的有效沟通以及对跨专业教育、综合培训和持续的跨学科咨询的需求,也被认为是真正合作医疗的关键因素。根据目标人群和服务类型的不同,现有模式的证据也大相径庭:结论:从理论和实践上讲,完全整合的跨学科医疗保健模式是可行的。将现有综合模式的各个方面结合起来并加以扩展,可以更加关注系统性因素,更加重视预防。根据这种新模式,医疗和牙科之家的概念可以扩展为以人为本的医疗保健之家,其中包括跨专业实践。由于采用了多层次的方法,这种跨学科方法有助于提高健康公平性。代表医学、牙科和行为健康护理各个领域的不同学科的多向整合对于所有人的最佳健康至关重要:本文可供临床医生、科学家、管理者和政策制定者在开发和实施综合医疗系统时使用,以满足患者的医疗、牙科和行为健康需求。
{"title":"Toward a Comprehensive Model of Medical-Dental-Behavioral Integration.","authors":"D W McNeil, D B Pereira, O S Ensz, K Lukose, G Harrell, D B Feller","doi":"10.1177/23800844241273836","DOIUrl":"10.1177/23800844241273836","url":null,"abstract":"<p><strong>Introduction: </strong>Existing models of medical-dental integration, as well as those from behavioral health care integrated with primary medical treatment, provide a basis for a truly synthesized and expanded model incorporating medical, dental, and behavioral components. Such a comprehensive model allows for collaborative health care serving patients seamlessly without disciplinary silos, promoting optimal whole-person health. This innovative approach is consistent with recent developments in the behavioral and social oral health sciences that include an imperative for their full inclusion in dental health care, research, and education.</p><p><strong>Methods: </strong>Existing models of medical-dental integration are described, along with current models from integrated primary medical and behavioral health care. Using these existing approaches as a basis, a new multilevel model is proposed to include social and cultural determinants of health.</p><p><strong>Results: </strong>Contemporary approaches to providing health care across disciplines include referral to a geographically separate entity, co-location of services, and integrated, side-by-side care. Integration of electronic health records and interoperability are necessary (but not sufficient) factors that affect transdisciplinary health care. Effective communication among health care providers and the need for interprofessional education, comprehensive training, and ongoing cross-disciplinary consultation also are noted as crucial factors in truly collaborative care. Evidence for existing models varies greatly depending on the target population and type of services provided.</p><p><strong>Conclusions: </strong>A fully integrated, transdisciplinary model of health care is possible, theoretically and practically. Combining aspects of extant integrated models and extending them provides opportunity for a greater focus on systemic factors and more emphasis on prevention. Consistent with this new model, medical and dental home concepts can be expanded to that of a person-centered health care home that includes interprofessional practice. This transdisciplinary approach contributes to greater health equity given the multilevel approach. Multidirectional integration of diverse disciplines representing the various realms of medicine, dentistry, and behavioral health care is essential for optimal health of all.</p><p><strong>Knowledge transfer statement: </strong>This article can be used by clinicians, scientists, administrators, and policy makers in developing and implementing integrated systems of care that provide for patients' medical, dental, and behavioral health needs.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":"9 1_suppl","pages":"23S-31S"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attitudes toward Adolescent Mental Health Screening in a Dental Setting: A Mixed-Methods Study. 在牙科环境中对青少年心理健康筛查的态度:混合方法研究
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1177/23800844241273775
S Ticku, S Nath, N Ramesh, C A Riedy

Introduction: Adolescents have experienced increasing levels of anxiety (AD) and depressive disorders (DD) in recent years. This study assessed the current attitudes of pediatric dentists and orthodontists on incorporating screenings for mental health disorders for their adolescent patients.

Methods: A sequential mixed-methods approach was used. A 35-item survey was sent to 5,538 pediatric dentists and orthodontists that included questions about attitudes and current screening practices for AD and DD. Multivariate logistic regression analysis was performed to examine factors associated with dentists' willingness to incorporate screening and discuss results with patients for AD and DD. Subsequently, we interviewed 16 orthodontists and pediatric dentists, conducted thematic analysis, and identified themes and subthemes.

Results: Based on 305 responses, >80% of respondents viewed screening for AD and DD as important, but <15% conducted screenings for them. Moreover, for those not screening, the odds of future screening for AD (odds ratio [OR]: 0.18, confidence interval [CI]: 0.08-0.43) and DD (OR: 0.23; CI: 0.09-0.56) were lower as the perceived importance of screening increased. Their willingness to screen for both AD (OR: 0.26, CI: 0.08-0.82) and DD (OR: 0.18, CI: 0.05-0.71) was also lower if they perceived this to negatively affect their patients' perception of them. The thematic analysis identified 3 main themes: (1) provider attitudes around mental health, (2) barriers to incorporating mental health screening, and (3) opportunities to integrate screening. Barriers included lack of training, access to mental health resources, and provider and patient stigma.

Conclusions: Our study showed that while most pediatric dentists and orthodontists understand the importance of screening their adolescent patients for AD and DD, many are unlikely to conduct screenings in the future. Obstacles such as inadequate training and stigma must be addressed for wider adoption. Further research and initiatives are crucial to tackle these challenges.

Knowledge transfer statement: The findings of this study offer insights to clinicians and policy makers into the attitudes, barriers, and facilitators among dentists-specifically pediatric dentists and orthodontists-who regularly treat adolescent patients, regarding mental health screenings for these individuals. This information can guide the development of initiatives, policy changes, and future research aimed at creating a more integrated dental care system that emphasizes the overall health of adolescent patients.

导言:近年来,青少年焦虑症(AD)和抑郁症(DD)的发病率越来越高。本研究评估了儿科牙医和口腔正畸医生目前对青少年患者进行心理健康疾病筛查的态度:方法:采用顺序混合方法。我们向5538名儿童牙医和正畸医生发送了一份包含35个项目的调查问卷,其中包括对AD和DD的态度和当前筛查做法的问题。我们进行了多变量逻辑回归分析,以研究牙医是否愿意进行 AD 和 DD 筛查并与患者讨论筛查结果的相关因素。随后,我们采访了 16 名正畸医师和儿童牙医,进行了主题分析,并确定了主题和次主题:结果:根据 305 份回复,超过 80% 的受访者认为 AD 和 DD 筛查很重要,但结论:我们的研究表明,虽然大多数儿科牙医和正畸医生都了解对青少年患者进行注意力缺失和注意力缺陷筛查的重要性,但许多人今后不太可能进行筛查。要想更广泛地采用筛查方法,必须解决培训不足和耻辱感等障碍。进一步的研究和举措对于应对这些挑战至关重要:本研究的结果为临床医生和政策制定者提供了洞察力,让他们了解牙科医生(尤其是儿童牙科医生和正畸医生)在为青少年患者进行心理健康筛查方面的态度、障碍和促进因素。这些信息可以指导制定计划、改变政策和开展未来研究,从而建立一个更加综合的牙科保健系统,重视青少年患者的整体健康。
{"title":"Attitudes toward Adolescent Mental Health Screening in a Dental Setting: A Mixed-Methods Study.","authors":"S Ticku, S Nath, N Ramesh, C A Riedy","doi":"10.1177/23800844241273775","DOIUrl":"10.1177/23800844241273775","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescents have experienced increasing levels of anxiety (AD) and depressive disorders (DD) in recent years. This study assessed the current attitudes of pediatric dentists and orthodontists on incorporating screenings for mental health disorders for their adolescent patients.</p><p><strong>Methods: </strong>A sequential mixed-methods approach was used. A 35-item survey was sent to 5,538 pediatric dentists and orthodontists that included questions about attitudes and current screening practices for AD and DD. Multivariate logistic regression analysis was performed to examine factors associated with dentists' willingness to incorporate screening and discuss results with patients for AD and DD. Subsequently, we interviewed 16 orthodontists and pediatric dentists, conducted thematic analysis, and identified themes and subthemes.</p><p><strong>Results: </strong>Based on 305 responses, >80% of respondents viewed screening for AD and DD as important, but <15% conducted screenings for them. Moreover, for those not screening, the odds of future screening for AD (odds ratio [OR]: 0.18, confidence interval [CI]: 0.08-0.43) and DD (OR: 0.23; CI: 0.09-0.56) were lower as the perceived importance of screening increased. Their willingness to screen for both AD (OR: 0.26, CI: 0.08-0.82) and DD (OR: 0.18, CI: 0.05-0.71) was also lower if they perceived this to negatively affect their patients' perception of them. The thematic analysis identified 3 main themes: (1) provider attitudes around mental health, (2) barriers to incorporating mental health screening, and (3) opportunities to integrate screening. Barriers included lack of training, access to mental health resources, and provider and patient stigma.</p><p><strong>Conclusions: </strong>Our study showed that while most pediatric dentists and orthodontists understand the importance of screening their adolescent patients for AD and DD, many are unlikely to conduct screenings in the future. Obstacles such as inadequate training and stigma must be addressed for wider adoption. Further research and initiatives are crucial to tackle these challenges.</p><p><strong>Knowledge transfer statement: </strong>The findings of this study offer insights to clinicians and policy makers into the attitudes, barriers, and facilitators among dentists-specifically pediatric dentists and orthodontists-who regularly treat adolescent patients, regarding mental health screenings for these individuals. This information can guide the development of initiatives, policy changes, and future research aimed at creating a more integrated dental care system that emphasizes the overall health of adolescent patients.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":"9 1_suppl","pages":"70S-87S"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental Surgical Activity in Hospitals during COVID-19: A Nationwide Observational Cohort Study. COVID-19 期间医院的牙科手术活动:全国观察性队列研究。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-01-03 DOI: 10.1177/23800844231216356
J Booth, A J Fowler, R Pearse, P Dias, Y I Wan, R Witton, T E F Abbott

Introduction: The number of surgical extractions performed in hospitals in England remains unclear. This study reports the volume of surgical extractions conducted in hospitals and change in activity during the COVID-19 pandemic.

Methods: We conducted a nationwide observational cohort study using Hospital Episode Statistics (HES) in England for patients undergoing surgical removal of a tooth (defined using OPSC-4 code F09) between April 1, 2015, and December 31, 2020. Procedures were stratified by age, gender, and urgency (elective or nonelective), reported using descriptive statistics, number, and percentage. We conducted post hoc modeling to predict surgical activity to December 2023. In addition, we contrasted this with aggregate national data on simple dental extraction procedures and drainage of dental abscesses in hospital as well as dental activity in general practice.

Results: We identified a total of 569,938 episodes for the surgical removal of a tooth (females 57%). Of these, 493,056/569,938 (87%) were for adults and 76,882/569,938 (13%) children ≤18 years. Surgical extractions were most frequent in adult females. Elective cases accounted for 96% (n = 548,805/569,938) of procedures. The median number of procedures carried out per quarter was 27,256, dropping to 12,003 during the COVID-19 pandemic, representing a 56% reduction in activity. This amounted to around 61,058 cancelled procedures. Modeling predicts that this activity has not returned to prepandemic levels.

Conclusions: The number of surgical extractions taking place in hospitals during the pandemic fell by 56%. The true impact of this reduction is unknown, but delayed treatment increases the risk of complications, including life-threatening infections.

Knowledge transfer statement: The result of this study provides an evidence-based overview of the trends relating to surgical extractions of teeth in England taking place in hospitals. This information can be used to inform service and workforce planning to meet the needs of patients requiring surgical extractions. The data also provide an insight into the oral health needs of the population in England.

介绍:英国医院进行的外科拔牙手术数量仍不清楚。本研究报告了在 COVID-19 大流行期间医院开展的手术拔牙数量及其变化情况:我们利用英格兰医院病例统计(HES)对 2015 年 4 月 1 日至 2020 年 12 月 31 日期间接受外科拔牙(使用 OPSC-4 代码 F09 定义)的患者进行了一项全国性的观察性队列研究。手术按年龄、性别和紧急程度(选择性或非选择性)进行分层,使用描述性统计、数量和百分比进行报告。我们进行了事后建模,以预测到 2023 年 12 月的手术活动。此外,我们还将其与全国简单拔牙手术、医院牙科脓肿引流以及全科牙科活动的总体数据进行了对比:我们共发现了 569,938 例手术拔牙病例(女性占 57%)。其中,493,056/569,938 例(87%)为成人,76,882/569,938 例(13%)为 18 岁以下儿童。手术拔牙在成年女性中最为常见。选择性手术占 96%(n = 548 805/569 938)。每季度进行的手术中位数为 27,256 例,在 COVID-19 大流行期间降至 12,003 例,活动减少了 56%。这相当于取消了约 61 058 例手术。根据模型预测,这一活动尚未恢复到大流行前的水平:结论:在流感大流行期间,医院进行的手术摘除数量减少了 56%。这一下降的真正影响尚不清楚,但延迟治疗会增加并发症的风险,包括危及生命的感染:这项研究的结果提供了一个以证据为基础的英格兰医院外科拔牙趋势概览。这些信息可用来指导服务和劳动力规划,以满足需要手术拔牙的患者的需求。这些数据还能让我们深入了解英格兰人口的口腔健康需求。
{"title":"Dental Surgical Activity in Hospitals during COVID-19: A Nationwide Observational Cohort Study.","authors":"J Booth, A J Fowler, R Pearse, P Dias, Y I Wan, R Witton, T E F Abbott","doi":"10.1177/23800844231216356","DOIUrl":"10.1177/23800844231216356","url":null,"abstract":"<p><strong>Introduction: </strong>The number of surgical extractions performed in hospitals in England remains unclear. This study reports the volume of surgical extractions conducted in hospitals and change in activity during the COVID-19 pandemic.</p><p><strong>Methods: </strong>We conducted a nationwide observational cohort study using Hospital Episode Statistics (HES) in England for patients undergoing surgical removal of a tooth (defined using OPSC-4 code F09) between April 1, 2015, and December 31, 2020. Procedures were stratified by age, gender, and urgency (elective or nonelective), reported using descriptive statistics, number, and percentage. We conducted post hoc modeling to predict surgical activity to December 2023. In addition, we contrasted this with aggregate national data on simple dental extraction procedures and drainage of dental abscesses in hospital as well as dental activity in general practice.</p><p><strong>Results: </strong>We identified a total of 569,938 episodes for the surgical removal of a tooth (females 57%). Of these, 493,056/569,938 (87%) were for adults and 76,882/569,938 (13%) children ≤18 years. Surgical extractions were most frequent in adult females. Elective cases accounted for 96% (<i>n</i> = 548,805/569,938) of procedures. The median number of procedures carried out per quarter was 27,256, dropping to 12,003 during the COVID-19 pandemic, representing a 56% reduction in activity. This amounted to around 61,058 cancelled procedures. Modeling predicts that this activity has not returned to prepandemic levels.</p><p><strong>Conclusions: </strong>The number of surgical extractions taking place in hospitals during the pandemic fell by 56%. The true impact of this reduction is unknown, but delayed treatment increases the risk of complications, including life-threatening infections.</p><p><strong>Knowledge transfer statement: </strong>The result of this study provides an evidence-based overview of the trends relating to surgical extractions of teeth in England taking place in hospitals. This information can be used to inform service and workforce planning to meet the needs of patients requiring surgical extractions. The data also provide an insight into the oral health needs of the population in England.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":" ","pages":"387-397"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11409558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139080576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers to Accessing Primary Dental Care in Adults with Alcohol Dependence: A Qualitative Study. 成人酒精依赖者获得初级牙科保健的障碍:定性研究。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-01-27 DOI: 10.1177/23800844231169642
C Bowes, M Breckons, R D Holmes, J Durham, B K Bareham

Background: People with alcohol dependence (AD) frequently experience oral health problems, but their dental attendance is poor, with limited evidence to the reasons why from their perspective.

Objective: To explore perceived barriers, motivators, and facilitators to accessing primary dental care in people with AD.

Methods: Qualitative study consisting of remote one-to-one and group semistructured interviews with a convenience sample of adults with lived experience of AD in northern England. Data were audio-recorded, transcribed, and coded. A reflexive thematic analysis method was used; use of COM-B model informed data interpretation.

Results: Twenty adults with lived experience of AD participated in 18 one-to-one interviews and 1 group interview (of 3 participants). Barriers to access were fear and physical, social, and environmental factors (physical effects of AD, financial barriers, nonprioritization of oral health). Motivators to access were pain and prioritization of oral health. Facilitators to access were patterns of alcohol use (i.e., sobriety) and dental service provision within recovery services.

Conclusions: Fear of "the dentist" is a major barrier to accessing dental care, and pain is the primary motivator, among people with AD, although neither are unique to this population. Fear and physical, social, and environmental barriers to access contribute to problem-oriented attendance, which negatively affect oral health outcomes. Opportunity to facilitate attendance increases when a person is in remission from AD through their physical capabilities improving. Increasing capability and opportunity can influence attendance beyond the automatic motivation of pain. Provision of dental care within recovery services could facilitate access to care. Understanding the "web of causation" is key to developing any intervention to improve dental access in people with AD. Further research is needed from the perspective of other adult populations with lived experience of AD, as well as of dental professionals, to gain deeper insight into barriers, facilitators, and possible solutions.

Knowledge transfer statement: The results of this study can help dental professionals understand factors affecting access to primary care in people with alcohol dependence to provide knowledge that may reduce stigma surrounding the disease. Results also demonstrate areas for intervention development for public policy.

背景:酒精依赖症(AD)患者经常会遇到口腔健康问题,但他们的牙科就诊率却很低,从他们的角度来看,只有有限的证据能说明其中的原因:探索酒精依赖症患者在接受初级牙科保健时感知到的障碍、动机和促进因素:定性研究包括远程一对一和小组半结构化访谈,访谈对象为英格兰北部有AD生活经历的成年人。对数据进行录音、转录和编码。采用反思性主题分析方法;使用 COM-B 模型对数据进行解释:20 名有注意力缺失症生活经历的成年人参加了 18 次一对一访谈和 1 次小组访谈(3 人参加)。获得治疗的障碍是恐惧以及身体、社会和环境因素(注意力缺失症对身体的影响、经济障碍、口腔健康不受重视)。获得治疗的动机是疼痛和优先考虑口腔健康。促进就诊的因素是饮酒模式(即清醒)和康复服务机构提供的牙科服务:结论:对 "牙医 "的恐惧是注意力缺失症患者获得牙科治疗的主要障碍,而疼痛则是其主要动机,尽管这两者都不是该人群所独有的。恐惧以及身体、社会和环境方面的障碍会导致以问题为导向的就诊,从而对口腔健康结果产生负面影响。当注意力缺失症患者的身体机能得到改善,病情得到缓解时,促进就诊的机会就会增加。能力的提高和机会的增加会影响就诊率,而不会仅仅因为疼痛而自动就诊。在康复服务中提供牙科护理可促进获得护理。了解 "因果关系网 "是制定任何干预措施以改善AD患者牙科就诊的关键。还需要从其他有AD生活经历的成年人群以及牙科专业人士的角度开展进一步研究,以便更深入地了解障碍、促进因素和可能的解决方案: 本研究的结果可以帮助牙科专业人员了解影响酒精依赖者获得初级保健的因素,从而提供可减少对该疾病的偏见的知识。研究结果还显示了公共政策干预发展的领域。
{"title":"Barriers to Accessing Primary Dental Care in Adults with Alcohol Dependence: A Qualitative Study.","authors":"C Bowes, M Breckons, R D Holmes, J Durham, B K Bareham","doi":"10.1177/23800844231169642","DOIUrl":"10.1177/23800844231169642","url":null,"abstract":"<p><strong>Background: </strong>People with alcohol dependence (AD) frequently experience oral health problems, but their dental attendance is poor, with limited evidence to the reasons why from their perspective.</p><p><strong>Objective: </strong>To explore perceived barriers, motivators, and facilitators to accessing primary dental care in people with AD.</p><p><strong>Methods: </strong>Qualitative study consisting of remote one-to-one and group semistructured interviews with a convenience sample of adults with lived experience of AD in northern England. Data were audio-recorded, transcribed, and coded. A reflexive thematic analysis method was used; use of COM-B model informed data interpretation.</p><p><strong>Results: </strong>Twenty adults with lived experience of AD participated in 18 one-to-one interviews and 1 group interview (of 3 participants). Barriers to access were fear and physical, social, and environmental factors (physical effects of AD, financial barriers, nonprioritization of oral health). Motivators to access were pain and prioritization of oral health. Facilitators to access were patterns of alcohol use (i.e., sobriety) and dental service provision within recovery services.</p><p><strong>Conclusions: </strong>Fear of \"the dentist\" is a major barrier to accessing dental care, and pain is the primary motivator, among people with AD, although neither are unique to this population. Fear and physical, social, and environmental barriers to access contribute to problem-oriented attendance, which negatively affect oral health outcomes. Opportunity to facilitate attendance increases when a person is in remission from AD through their physical capabilities improving. Increasing capability and opportunity can influence attendance beyond the automatic motivation of pain. Provision of dental care within recovery services could facilitate access to care. Understanding the \"web of causation\" is key to developing any intervention to improve dental access in people with AD. Further research is needed from the perspective of other adult populations with lived experience of AD, as well as of dental professionals, to gain deeper insight into barriers, facilitators, and possible solutions.</p><p><strong>Knowledge transfer statement: </strong>\u0000 <i>The results of this study can help dental professionals understand factors affecting access to primary care in people with alcohol dependence to provide knowledge that may reduce stigma surrounding the disease. Results also demonstrate areas for intervention development for public policy.</i>\u0000 </p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":" ","pages":"325-336"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139567317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical-Dental-Behavioral Integration: Embracing Whole-Person Health in Research and Practice. 医疗-牙科-行为一体化:在研究和实践中拥抱全人健康。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1177/23800844241273799
L J Heaton, T Tiwari, E P Tranby

Knowledge transfer statement: The goal of this editorial and following supplement articles is to present different perspectives on the implementation of medical-dental-behavioral integration to provide comprehensive, whole-person care. Through a discussion of barriers to and opportunities that emerge from this type of integrated care, this editorial and supplement provide strong evidence for the importance, feasibility, and necessity of integrated health care and concept of overall health.

知识转移声明:本社论及后续补充文章旨在从不同角度介绍医疗-牙科-行为一体化的实施情况,以提供全面的全人医疗服务。通过对这种综合护理的障碍和机遇的讨论,这篇社论和增刊为综合医疗护理和整体健康概念的重要性、可行性和必要性提供了有力的证据。
{"title":"Medical-Dental-Behavioral Integration: Embracing Whole-Person Health in Research and Practice.","authors":"L J Heaton, T Tiwari, E P Tranby","doi":"10.1177/23800844241273799","DOIUrl":"10.1177/23800844241273799","url":null,"abstract":"<p><strong>Knowledge transfer statement: </strong>The goal of this editorial and following supplement articles is to present different perspectives on the implementation of medical-dental-behavioral integration to provide comprehensive, whole-person care. Through a discussion of barriers to and opportunities that emerge from this type of integrated care, this editorial and supplement provide strong evidence for the importance, feasibility, and necessity of integrated health care and concept of overall health.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":"9 1_suppl","pages":"3S-5S"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating Periodontitis Susceptibility Cases for Epidemiological Studies with Multiple Imputation. 用多重推算法估算流行病学研究中的牙周炎易感病例
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-03-14 DOI: 10.1177/23800844241228277
L Zhang, M Xiao, H Chu, G A Kotsakis, W Guan

Knowledge transfer statement: Our proposed estimate of periodontitis susceptibility cases addresses the issue of missing teeth, offering an innovative solution through a generative missing data imputation model. The implications of our findings extend to fostering more robust investigations into the relationships between periodontal health and systemic diseases, thereby offering valuable insights to clinicians for informed decision-making. Moreover, the study's capacity to shape clinical practices and interventions in public health will further fortify health policy strategies.

知识转移声明:我们提出的牙周炎易感病例估计值解决了缺失牙齿的问题,通过一种生成性缺失数据估算模型提供了一种创新的解决方案。我们研究结果的意义在于促进对牙周健康与系统性疾病之间的关系进行更有力的调查,从而为临床医生做出明智决策提供有价值的见解。此外,这项研究对临床实践和公共卫生干预措施的影响将进一步强化卫生政策战略。
{"title":"Estimating Periodontitis Susceptibility Cases for Epidemiological Studies with Multiple Imputation.","authors":"L Zhang, M Xiao, H Chu, G A Kotsakis, W Guan","doi":"10.1177/23800844241228277","DOIUrl":"10.1177/23800844241228277","url":null,"abstract":"<p><strong>Knowledge transfer statement: </strong>Our proposed estimate of periodontitis susceptibility cases addresses the issue of missing teeth, offering an innovative solution through a generative missing data imputation model. The implications of our findings extend to fostering more robust investigations into the relationships between periodontal health and systemic diseases, thereby offering valuable insights to clinicians for informed decision-making. Moreover, the study's capacity to shape clinical practices and interventions in public health will further fortify health policy strategies.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":" ","pages":"378-386"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suboptimal Oral Health, Multimorbidity, and Access to Dental Care. 口腔健康状况欠佳、多病症和牙科保健的可及性。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1177/23800844241273760
L Limo, K Nicholson, S Stranges, N Gomaa

Introduction: Emerging studies on the links between suboptimal oral health and multimorbidity (MM), or the co-existence of multiple chronic conditions, have raised controversy as to whether enhancing access to dental care may mitigate MM in those with suboptimal oral health. In this study, we aim to assess the extent of the association between suboptimal oral health and MM and whether access to dental care can modify this association.

Methods: We conducted a cross-sectional analysis using data from the Canadian Longitudinal Study on Aging (CLSA) (N = 44,815, 45 to 84 y old). Edentulism, self-reported oral health (SROH), and other oral health problems (e.g., toothache, bleeding gums) were used as indicators of suboptimal oral health. MM was defined according to the Public Health Agency of Canada as having 2 or more of the following chronic conditions: cancer, cardiovascular diseases, chronic respiratory diseases, diabetes, and mental illnesses. For robustness, we also used a cutoff of having 3 or more of these chronic conditions. Variables for access to dental care included (1) dental visits within the past year, (2) availability of dental insurance, and (3) cost barriers to dental care. We constructed robust Poisson regression models to estimate the association between suboptimal oral health and MM and then assessed the effect measure modification by indicators of access to dental care on a multiplicative scale. We also calculated the relative excess risk due to interaction for prevalence ratio (PR) on an additive scale.

Results: Indicators of suboptimal oral health were significantly associated with MM (edentulism PR 1.17, 95% confidence interval [CI] 1.08, 1.27; poor SROH PR 1.44, 95% CI 1.33, 1.54; other oral health problems PR 1.52, 95% CI 1.44, 1.78). The magnitude of this association was higher in individuals who reported fewer dental visits within the past year, lacked dental insurance, and avoided dental care due to costs.

Conclusion: The association between suboptimal oral health and MM may be exacerbated by barriers to accessing dental care. Policies aiming to enhance access to dental care may help mitigate MM in middle-aged and older Canadians with suboptimal oral health.

Knowledge transfer statement: This study offers insights into the connection among suboptimal oral health, multimorbidity, and access to dental care factors in middle-aged and older Canadians. The findings can be of value for clinicians and policy makers aiming to enhance medical-dental integration and improve accessibility to dental care and to patients seeking information about the connections between oral health and chronic conditions. Implementation has the potential to enhance individual well-being and drive systemic improvements in health care.

导言:关于口腔健康不达标与多病症(MM)或多种慢性病并存之间的联系的新研究引起了争议,即提高牙科保健的可及性是否可以减轻口腔健康不达标人群的多病症。在这项研究中,我们旨在评估口腔健康欠佳与 MM 之间的关联程度,以及获得牙科保健是否能改变这种关联:我们利用加拿大老龄化纵向研究(CLSA)的数据(N = 44,815 人,45 至 84 岁)进行了横断面分析。缺牙症、自我报告的口腔健康状况(SROH)和其他口腔健康问题(如牙痛、牙龈出血)被用作口腔健康欠佳的指标。根据加拿大公共卫生局的定义,MM 是指患有 2 种或 2 种以上以下慢性疾病:癌症、心血管疾病、慢性呼吸系统疾病、糖尿病和精神疾病。为了稳健起见,我们还以患有 3 种或 3 种以上慢性病为分界线。获得牙科保健的变量包括:(1)过去一年中的牙科就诊情况;(2)是否有牙科保险;(3)牙科保健的费用障碍。我们构建了稳健的泊松回归模型来估计口腔健康欠佳与 MM 之间的关联,然后以乘法尺度评估了获得牙科保健的指标对效应测量的修正。我们还计算了患病率比值(PR)相互作用的相对超额风险:结果:口腔健康不达标的指标与 MM 有显著相关性(龋齿 PR 1.17,95% 置信区间 [CI] 1.08,1.27;口腔卫生不良 PR 1.44,95% 置信区间 [CI] 1.33,1.54;其他口腔健康问题 PR 1.52,95% 置信区间 [CI] 1.44,1.78)。在过去一年中牙科就诊次数较少、没有牙科保险以及因费用问题而避免接受牙科治疗的人群中,这种关联的程度更高:结论:口腔健康欠佳与 MM 之间的关联可能因获得牙科保健的障碍而加剧。旨在增加获得牙科保健机会的政策可能有助于减轻口腔健康欠佳的中老年加拿大人的MM:本研究深入探讨了加拿大中老年人口腔健康欠佳、多病和获得牙科保健因素之间的联系。研究结果对旨在加强医疗与牙科结合、改善牙科保健可及性的临床医生和政策制定者,以及寻求有关口腔健康与慢性病之间联系的信息的患者都很有价值。该研究的实施有可能提高个人的健康水平,推动医疗保健的系统性改善。
{"title":"Suboptimal Oral Health, Multimorbidity, and Access to Dental Care.","authors":"L Limo, K Nicholson, S Stranges, N Gomaa","doi":"10.1177/23800844241273760","DOIUrl":"10.1177/23800844241273760","url":null,"abstract":"<p><strong>Introduction: </strong>Emerging studies on the links between suboptimal oral health and multimorbidity (MM), or the co-existence of multiple chronic conditions, have raised controversy as to whether enhancing access to dental care may mitigate MM in those with suboptimal oral health. In this study, we aim to assess the extent of the association between suboptimal oral health and MM and whether access to dental care can modify this association.</p><p><strong>Methods: </strong>We conducted a cross-sectional analysis using data from the Canadian Longitudinal Study on Aging (CLSA) (N = 44,815, 45 to 84 y old). Edentulism, self-reported oral health (SROH), and other oral health problems (e.g., toothache, bleeding gums) were used as indicators of suboptimal oral health. MM was defined according to the Public Health Agency of Canada as having 2 or more of the following chronic conditions: cancer, cardiovascular diseases, chronic respiratory diseases, diabetes, and mental illnesses. For robustness, we also used a cutoff of having 3 or more of these chronic conditions. Variables for access to dental care included (1) dental visits within the past year, (2) availability of dental insurance, and (3) cost barriers to dental care. We constructed robust Poisson regression models to estimate the association between suboptimal oral health and MM and then assessed the effect measure modification by indicators of access to dental care on a multiplicative scale. We also calculated the relative excess risk due to interaction for prevalence ratio (PR) on an additive scale.</p><p><strong>Results: </strong>Indicators of suboptimal oral health were significantly associated with MM (edentulism PR 1.17, 95% confidence interval [CI] 1.08, 1.27; poor SROH PR 1.44, 95% CI 1.33, 1.54; other oral health problems PR 1.52, 95% CI 1.44, 1.78). The magnitude of this association was higher in individuals who reported fewer dental visits within the past year, lacked dental insurance, and avoided dental care due to costs.</p><p><strong>Conclusion: </strong>The association between suboptimal oral health and MM may be exacerbated by barriers to accessing dental care. Policies aiming to enhance access to dental care may help mitigate MM in middle-aged and older Canadians with suboptimal oral health.</p><p><strong>Knowledge transfer statement: </strong>This study offers insights into the connection among suboptimal oral health, multimorbidity, and access to dental care factors in middle-aged and older Canadians. The findings can be of value for clinicians and policy makers aiming to enhance medical-dental integration and improve accessibility to dental care and to patients seeking information about the connections between oral health and chronic conditions. Implementation has the potential to enhance individual well-being and drive systemic improvements in health care.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":"9 1_suppl","pages":"13S-22S"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
JDR Clinical & Translational Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1