Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240355
Marcia M M Pizzichini, Álvaro A Cruz, Emilio Pizzichini
{"title":"Is asthma mortality decreasing or increasing in Brazil? The burden of proof.","authors":"Marcia M M Pizzichini, Álvaro A Cruz, Emilio Pizzichini","doi":"10.36416/1806-3756/e20240355","DOIUrl":"10.36416/1806-3756/e20240355","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240355"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240217
Matheus de Almeida Costa, Miriam Menna Barreto, Edson Marchiori
{"title":"Pulmonary hemorrhage in a patient with Marfan syndrome.","authors":"Matheus de Almeida Costa, Miriam Menna Barreto, Edson Marchiori","doi":"10.36416/1806-3756/e20240217","DOIUrl":"10.36416/1806-3756/e20240217","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240217"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240349
Erich Vidal Carvalho, Lídia Maria Carneiro da Fonseca, Bruno Valle Pinheiro
{"title":"ELMO-CPAP: an effective approach in the management of patients with acute hypoxemic respiratory failure.","authors":"Erich Vidal Carvalho, Lídia Maria Carneiro da Fonseca, Bruno Valle Pinheiro","doi":"10.36416/1806-3756/e20240349","DOIUrl":"10.36416/1806-3756/e20240349","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240349"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240345
Juliana C Ferreira, Cecilia M Patino
{"title":"How to become a productive academic writer?","authors":"Juliana C Ferreira, Cecilia M Patino","doi":"10.36416/1806-3756/e20240345","DOIUrl":"10.36416/1806-3756/e20240345","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240345"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240192
Guilherme das Posses Bridi, Ronaldo Adib Kairalla, Márcio Valente Yamada Sawamura, Bruno Guedes Baldi
{"title":"Acid sphingomyelinase deficiency with homozygous p.Arg610del genotype in an elderly patient: a rare case report.","authors":"Guilherme das Posses Bridi, Ronaldo Adib Kairalla, Márcio Valente Yamada Sawamura, Bruno Guedes Baldi","doi":"10.36416/1806-3756/e20240192","DOIUrl":"10.36416/1806-3756/e20240192","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240192"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240222
Diego Corsetti Mondadori, Flavio Pola Dos Reis, Fernando Antibas Atik, Luciana Bertocco de Paiva Haddad, Paulo Manuel Pêgo-Fernandes
{"title":"Revitalizing Brazil's contribution to the International Society for Heart and Lung Transplantation Lung Transplant Database.","authors":"Diego Corsetti Mondadori, Flavio Pola Dos Reis, Fernando Antibas Atik, Luciana Bertocco de Paiva Haddad, Paulo Manuel Pêgo-Fernandes","doi":"10.36416/1806-3756/e20240222","DOIUrl":"10.36416/1806-3756/e20240222","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240222"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06eCollection Date: 2024-01-01DOI: 10.36416/1806-3756/e20240299
Isabella de Melo Matos, Betina Santos Tomaz, Maria da Penha Uchoa Sales, Gabriela Carvalho Gomes, Antonio Brazil Viana Junior, Miguel R Gonçalves, Marcelo Alcantara Holanda, Eanes Delgado Barros Pereira
Objective: This study aimed to describe the outcomes and explore predictors of intubation and mortality in patients with ARDS due to COVID-19 treated with CPAP delivered via a helmet interface and light sedation.
Methods: This was a retrospective cohort study involving patients with COVID-19-related ARDS who received CPAP using a helmet developed in Brazil (ELMO™), associated with a light sedation protocol in a pulmonology ward. Demographic, clinical, imaging, and laboratory data, as well as the duration and response to the ELMO-CPAP sessions, were analyzed.
Results: The sample comprised 180 patients. The intubation avoidance rate was 72.8%. The lack of necessity for intubation was positively correlated with younger age, > 24-h continuous HELMET-CPAP use in the first session, < 75% pulmonary involvement on CT, and ROX index > 4.88 in the second hour. The overall in-hospital mortality rate was 18.9%, whereas those in the nonintubated and intubated groups were 3.0% and 61.2%, respectively. Advanced age increased the mortality risk by 2.8 times, escalating to 13 times post-intubation.
Conclusions: ELMO-CPAP with light sedation in a pulmonology ward was successful in > 70% of patients with moderate to severe ARDS due to COVID-19. Younger age, pulmonary involvement, ROX index, and prolonged first Helmet-CPAP session duration were associated with no need for intubation. Older age and intubation are associated with mortality.
{"title":"CPAP delivered via a helmet interface in lightly sedated patients with moderate to severe ARDS: predictors of success outside the ICU.","authors":"Isabella de Melo Matos, Betina Santos Tomaz, Maria da Penha Uchoa Sales, Gabriela Carvalho Gomes, Antonio Brazil Viana Junior, Miguel R Gonçalves, Marcelo Alcantara Holanda, Eanes Delgado Barros Pereira","doi":"10.36416/1806-3756/e20240299","DOIUrl":"10.36416/1806-3756/e20240299","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to describe the outcomes and explore predictors of intubation and mortality in patients with ARDS due to COVID-19 treated with CPAP delivered via a helmet interface and light sedation.</p><p><strong>Methods: </strong>This was a retrospective cohort study involving patients with COVID-19-related ARDS who received CPAP using a helmet developed in Brazil (ELMO™), associated with a light sedation protocol in a pulmonology ward. Demographic, clinical, imaging, and laboratory data, as well as the duration and response to the ELMO-CPAP sessions, were analyzed.</p><p><strong>Results: </strong>The sample comprised 180 patients. The intubation avoidance rate was 72.8%. The lack of necessity for intubation was positively correlated with younger age, > 24-h continuous HELMET-CPAP use in the first session, < 75% pulmonary involvement on CT, and ROX index > 4.88 in the second hour. The overall in-hospital mortality rate was 18.9%, whereas those in the nonintubated and intubated groups were 3.0% and 61.2%, respectively. Advanced age increased the mortality risk by 2.8 times, escalating to 13 times post-intubation.</p><p><strong>Conclusions: </strong>ELMO-CPAP with light sedation in a pulmonology ward was successful in > 70% of patients with moderate to severe ARDS due to COVID-19. Younger age, pulmonary involvement, ROX index, and prolonged first Helmet-CPAP session duration were associated with no need for intubation. Older age and intubation are associated with mortality.</p>","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240299"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240246
Ellys Rhaiara Nunes Rebouças, Taynara Rodrigues Ramos, Barbara Galdino de Sousa, Rayana Fialho da Costa, Samara Sousa Vasconcelos Gouveia, Italo Caldas Silva, Daniela Gardano Bucharles Mont'Alverne, Nataly Gurgel Campos
{"title":"Long COVID: a cross-sectional study of respiratory muscle strength, lung function, and persistent symptoms at one year after hospital discharge.","authors":"Ellys Rhaiara Nunes Rebouças, Taynara Rodrigues Ramos, Barbara Galdino de Sousa, Rayana Fialho da Costa, Samara Sousa Vasconcelos Gouveia, Italo Caldas Silva, Daniela Gardano Bucharles Mont'Alverne, Nataly Gurgel Campos","doi":"10.36416/1806-3756/e20240246","DOIUrl":"10.36416/1806-3756/e20240246","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240246"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06eCollection Date: 2024-01-01DOI: 10.36416/1806-3756/e20240058
Catarina Gouveia Cardoso, Carolina Valente, Mariana Serino, Inês Rodrigues, André Carvalho, David Barros Coelho, Hélder Novais Bastos, Patrícia Caetano Mota, António Morais, Marta Drummond
Objective: The frequency of obstructive sleep apnea (OSA) in patients with idiopathic pulmonary fibrosis (IPF) is high. The clinical course of non-IPF interstitial lung disease (ILD) can be similar to that of IPF. We sought to assess the frequency and predictors of OSA in patients with non-IPF fibrotic ILD, as well as the impact of positive airway pressure (PAP) therapy on the quality of life of such patients.
Methods: This was a prospective study in which non-IPF fibrotic ILD patients underwent a home sleep apnea test. The patients with and without OSA were compared, and a multivariate logistic regression model was used to identify independent predictors of OSA. At 3 months after initiation of PAP therapy, we evaluated the participating patients for respiratory events, nocturnal hypoxemia, and changes in quality of life.
Results: Of a total of 50 patients, 50% were male, and 76% were diagnosed with OSA. The mean age was 67.8 ± 8.3 years. The patients with OSA had significantly lower TLC (p = 0.033) and awake SpO2 (p = 0.023) than did those without OSA. In the multivariate logistic regression model, SpO2 (OR = 0.46; p = 0.016) and TLC (OR = 0.95; p = 0.026) remained significantly associated with OSA risk. A total of 12 patients received PAP therapy. At 3 months after initiation of PAP therapy, 91.7% were well controlled, Epworth Sleepiness Scale scores decreased significantly (p = 0.006), and emotional well-being tended to improve (p = 0.068). PAP therapy corrected nocturnal hypoxemia in all patients.
Conclusions: We found a high frequency of OSA in patients with non-IPF fibrotic ILD. A low TLC was an independent predictor of a higher risk of OSA. PAP therapy can correct nocturnal hypoxemia. There should be a low threshold for suspicion of OSA and initiation of PAP therapy in patients with non-IPF fibrotic ILD.
{"title":"Obstructive sleep apnea in patients with fibrotic interstitial lung disease (non-idiopathic pulmonary fibrosis): what should be offered?","authors":"Catarina Gouveia Cardoso, Carolina Valente, Mariana Serino, Inês Rodrigues, André Carvalho, David Barros Coelho, Hélder Novais Bastos, Patrícia Caetano Mota, António Morais, Marta Drummond","doi":"10.36416/1806-3756/e20240058","DOIUrl":"10.36416/1806-3756/e20240058","url":null,"abstract":"<p><strong>Objective: </strong>The frequency of obstructive sleep apnea (OSA) in patients with idiopathic pulmonary fibrosis (IPF) is high. The clinical course of non-IPF interstitial lung disease (ILD) can be similar to that of IPF. We sought to assess the frequency and predictors of OSA in patients with non-IPF fibrotic ILD, as well as the impact of positive airway pressure (PAP) therapy on the quality of life of such patients.</p><p><strong>Methods: </strong>This was a prospective study in which non-IPF fibrotic ILD patients underwent a home sleep apnea test. The patients with and without OSA were compared, and a multivariate logistic regression model was used to identify independent predictors of OSA. At 3 months after initiation of PAP therapy, we evaluated the participating patients for respiratory events, nocturnal hypoxemia, and changes in quality of life.</p><p><strong>Results: </strong>Of a total of 50 patients, 50% were male, and 76% were diagnosed with OSA. The mean age was 67.8 ± 8.3 years. The patients with OSA had significantly lower TLC (p = 0.033) and awake SpO2 (p = 0.023) than did those without OSA. In the multivariate logistic regression model, SpO2 (OR = 0.46; p = 0.016) and TLC (OR = 0.95; p = 0.026) remained significantly associated with OSA risk. A total of 12 patients received PAP therapy. At 3 months after initiation of PAP therapy, 91.7% were well controlled, Epworth Sleepiness Scale scores decreased significantly (p = 0.006), and emotional well-being tended to improve (p = 0.068). PAP therapy corrected nocturnal hypoxemia in all patients.</p><p><strong>Conclusions: </strong>We found a high frequency of OSA in patients with non-IPF fibrotic ILD. A low TLC was an independent predictor of a higher risk of OSA. PAP therapy can correct nocturnal hypoxemia. There should be a low threshold for suspicion of OSA and initiation of PAP therapy in patients with non-IPF fibrotic ILD.</p>","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240058"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-06DOI: 10.36416/1806-3756/e20240237
José Alberto Neder, Denis E O'Donnell, Danilo C Berton
{"title":"The role of the pulmonary function laboratory in the management of hematologic diseases.","authors":"José Alberto Neder, Denis E O'Donnell, Danilo C Berton","doi":"10.36416/1806-3756/e20240237","DOIUrl":"10.36416/1806-3756/e20240237","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 5","pages":"e20240237"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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