S. Bessi, U. Malapelle, P. Pisapia, F. Pepe, M. Ottaviantonio, G. Troncone, M. Biancalani
{"title":"ERBB2 VARIANTS DISTRIBUTION IN NON-SMALL CELL LUNG CANCER: AN ITALIAN REAL-WORLD EXPERIENCE","authors":"S. Bessi, U. Malapelle, P. Pisapia, F. Pepe, M. Ottaviantonio, G. Troncone, M. Biancalani","doi":"10.48286/aro.2023.67","DOIUrl":"https://doi.org/10.48286/aro.2023.67","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124168275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Crispo, S. Coluccia, S. Vitale, E. Palumbo, G. Porciello, A. Luongo, M. Prete, E. Coppola, C. Montagnese, P. Di Gennaro, M. Grimaldi, R. Pica, E. Rotondo, E. Celentano, F. Izzo, A. Amore, M. Cascella, F. Perri, M. de Laurentiis, L. Augustin
{"title":"MOLECULAR SUBTYPES AND DIETARY PATTERNS IN BREAST CANCER PATIENTS: A LATENT CLASS ANALYSIS","authors":"A. Crispo, S. Coluccia, S. Vitale, E. Palumbo, G. Porciello, A. Luongo, M. Prete, E. Coppola, C. Montagnese, P. Di Gennaro, M. Grimaldi, R. Pica, E. Rotondo, E. Celentano, F. Izzo, A. Amore, M. Cascella, F. Perri, M. de Laurentiis, L. Augustin","doi":"10.48286/aro.2023.68","DOIUrl":"https://doi.org/10.48286/aro.2023.68","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129952980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Da Prat, E. Colombo, G. Preziati, L. Perrone, F. Serra, R. Caccialanza, P. Pedrazzoli
{"title":"THE COMPLEX REALITY OF MALNUTRITION MANAGEMENT IN ONCOLOGY","authors":"V. Da Prat, E. Colombo, G. Preziati, L. Perrone, F. Serra, R. Caccialanza, P. Pedrazzoli","doi":"10.48286/aro.2023.66","DOIUrl":"https://doi.org/10.48286/aro.2023.66","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123576532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Cau, C. Gerosa, G. Ziranu, A. Pretta, R. Murru, M. Fraschini, M. Piras, P. Eyken, G. La Nasa, M. Castagnola, F. Coghe, G. Orrù, L. Zorcolo, D. Fanni, M. Scartozzi, G. Faa
{"title":"L1CAM EXPRESSION IDENTIFIES DIFFERENT COLORECTAL TUMOR SUBGROUPS","authors":"F. Cau, C. Gerosa, G. Ziranu, A. Pretta, R. Murru, M. Fraschini, M. Piras, P. Eyken, G. La Nasa, M. Castagnola, F. Coghe, G. Orrù, L. Zorcolo, D. Fanni, M. Scartozzi, G. Faa","doi":"10.48286/aro.2023.69","DOIUrl":"https://doi.org/10.48286/aro.2023.69","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124596609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A BRIEF OVERVIEW OF SEVERAL RECENT ADVANCEMENTS OF TARGETED-THERAPIES AND ANTIBODY-CONJUGATE DRUGS FOR ADVANCED TRIPLE-NEGATIVE BREAST CANCER","authors":"S. Burk, A. Morrione","doi":"10.48286/aro.2023.65","DOIUrl":"https://doi.org/10.48286/aro.2023.65","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122703021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. De Biase, V. Baldassarre, G. Piegari, G. Rosato, V. Caputo, M. Pompameo, P. Sarnelli, V. Russo, D. D'Angelo, S. Papparella
{"title":"ANIMAL SENTINELS AND CANCER REGISTRIES: STATE OF THE ART AND NEW PERSPECTIVES","authors":"D. De Biase, V. Baldassarre, G. Piegari, G. Rosato, V. Caputo, M. Pompameo, P. Sarnelli, V. Russo, D. D'Angelo, S. Papparella","doi":"10.48286/aro.2023.61","DOIUrl":"https://doi.org/10.48286/aro.2023.61","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"168 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128630231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE NEW SHAPE OF THE ITALIAN ETHICS COMMITTEES","authors":"C. Cagnazzo, F. Fagioli","doi":"10.48286/aro.2023.63","DOIUrl":"https://doi.org/10.48286/aro.2023.63","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115722381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Comandone, I. Persano, T. Comandone, A. Boglione
{"title":"EWING SARCOMA: A REAPPRAISAL","authors":"A. Comandone, I. Persano, T. Comandone, A. Boglione","doi":"10.48286/aro.2023.64","DOIUrl":"https://doi.org/10.48286/aro.2023.64","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121236408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BRIDGING THE GAP BETWEEN RESEARCH AND CURE IN RARE GYNAECOLOGICAL CANCERS: WHERE DO WE STAND? REPORT FROM THE GYNOCARE CONFERENCE IN NAPLES (17-18TH FEBRUARY 2023)","authors":"J. Calleja-Agius","doi":"10.48286/aro.2023.62","DOIUrl":"https://doi.org/10.48286/aro.2023.62","url":null,"abstract":"","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126343820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Agius, C. Camenzuli, David Pisani, Riccardo Di Fiore, Alberto Vella, James De Gaetano, Daiva Vaitkiene, Nuno Nogueira Martins, Jean Calleja-Agius
: Malignant neoplasms that show divergent differentiation, like squamous cell carcinoma (SCC) and small cell neuroendocrine carcinoma (SNEC), occur very rarely in the cervix. Neuroendocrine tumors of the female genital tract tend to occur in combination with other types of tumors although they have been also described to occur as solitary neoplasms. Here, we present a case of a 51-year-old woman with a one-month history of vaginal bleeding and one week history of persistent lower abdominal pain. On vaginal examination a large irregular fixed cylindrical mass in mid-vagina, extending to the cervix, was felt. A computerized tomographic scan showed a uterine mass with retroperitoneal and pelvic lymphadenopathy together with multiple bilateral lung metastases. Cytological analysis via a cervical pap smear reported a high-grade intraepithelial lesion and atypical glandular cells of undetermined significance. Histological analysis of the cervical biopsies showed a necrotic biphasic neoplasm. The morphological and immunohistochemical findings were those of a poorly differentiated carcinoma with squamous and high grade neuroendocrine (small cell) differentiation. Polymerase chain reaction analysis for Human Papilloma Virus (HPV) performed on shavings from the paraffin-embedded tissue showed no evidence of HPV DNA. The patient was planned to receive primary chemotherapy but passed away within 3 weeks of her diagnosis. In conclusion, tumors showing SNEC differentiation, together with rare cases of primary cervical SNEC exhibit a different disease profile when compared with pure cervical SCC, in that the former are highly aggressive and has a greater propensity for nodal and distant organ metastasis. These tumors are associated with a poor prognosis.
{"title":"A CASE REPORT OF HPV NEGATIVE SMALL CELL NEUROENDOCRINE CARCINOMA AND SQUAMOUS CELL CARCINOMA OF THE CERVIX: A RARE BUT FATAL MIX","authors":"A. Agius, C. Camenzuli, David Pisani, Riccardo Di Fiore, Alberto Vella, James De Gaetano, Daiva Vaitkiene, Nuno Nogueira Martins, Jean Calleja-Agius","doi":"10.48286/aro.2023.60","DOIUrl":"https://doi.org/10.48286/aro.2023.60","url":null,"abstract":": Malignant neoplasms that show divergent differentiation, like squamous cell carcinoma (SCC) and small cell neuroendocrine carcinoma (SNEC), occur very rarely in the cervix. Neuroendocrine tumors of the female genital tract tend to occur in combination with other types of tumors although they have been also described to occur as solitary neoplasms. Here, we present a case of a 51-year-old woman with a one-month history of vaginal bleeding and one week history of persistent lower abdominal pain. On vaginal examination a large irregular fixed cylindrical mass in mid-vagina, extending to the cervix, was felt. A computerized tomographic scan showed a uterine mass with retroperitoneal and pelvic lymphadenopathy together with multiple bilateral lung metastases. Cytological analysis via a cervical pap smear reported a high-grade intraepithelial lesion and atypical glandular cells of undetermined significance. Histological analysis of the cervical biopsies showed a necrotic biphasic neoplasm. The morphological and immunohistochemical findings were those of a poorly differentiated carcinoma with squamous and high grade neuroendocrine (small cell) differentiation. Polymerase chain reaction analysis for Human Papilloma Virus (HPV) performed on shavings from the paraffin-embedded tissue showed no evidence of HPV DNA. The patient was planned to receive primary chemotherapy but passed away within 3 weeks of her diagnosis. In conclusion, tumors showing SNEC differentiation, together with rare cases of primary cervical SNEC exhibit a different disease profile when compared with pure cervical SCC, in that the former are highly aggressive and has a greater propensity for nodal and distant organ metastasis. These tumors are associated with a poor prognosis.","PeriodicalId":148778,"journal":{"name":"Annals of Research in Oncology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129991803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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