Pub Date : 2022-02-12DOI: 10.1007/s41664-022-00209-z
M. Yadav, Geeta Singh, S. Lata
{"title":"Revisiting Some Recently Developed Conducting Polymer@Metal Oxide Nanostructures for Electrochemical Sensing of Vital Biomolecules: A Review","authors":"M. Yadav, Geeta Singh, S. Lata","doi":"10.1007/s41664-022-00209-z","DOIUrl":"https://doi.org/10.1007/s41664-022-00209-z","url":null,"abstract":"","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"1 1","pages":"274 - 295"},"PeriodicalIF":4.7,"publicationDate":"2022-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83675312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-10DOI: 10.1007/s41664-022-00210-6
Hui Zhang, Wu-Kui Kang, Ying Wang, Xiuhua Wang, Li Lu
{"title":"An Enzymatic Reaction Modulated Fluorescence-on Omethoate Biosensor Based on Fe3O4@GO and Copper Nanoparticles","authors":"Hui Zhang, Wu-Kui Kang, Ying Wang, Xiuhua Wang, Li Lu","doi":"10.1007/s41664-022-00210-6","DOIUrl":"https://doi.org/10.1007/s41664-022-00210-6","url":null,"abstract":"","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"6 1","pages":"3 - 11"},"PeriodicalIF":4.7,"publicationDate":"2022-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89302204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-25DOI: 10.1007/s41664-021-00208-6
Tianyu Wang, R. Guo, Longlong Hu, Jingjing Liu, Haitao Lu
{"title":"Mass Spectrometry-Based Targeted Metabolomics Revealed the Regulatory Roles of Magnesium on Biofilm Formation in Escherichia coli by Targeting Functional Metabolites","authors":"Tianyu Wang, R. Guo, Longlong Hu, Jingjing Liu, Haitao Lu","doi":"10.1007/s41664-021-00208-6","DOIUrl":"https://doi.org/10.1007/s41664-021-00208-6","url":null,"abstract":"","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"9 1","pages":"89 - 97"},"PeriodicalIF":4.7,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88872123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-24DOI: 10.1007/s41664-021-00206-8
Yu-Rong Yan, Dan Zhao, Qiang Zhang, Yangyang Chang, Meng Liu
{"title":"A Thermophilic G-Quadruplex DNA/N-methylmesoporphyrin IX Sensor for Accurately Detecting Single Nucleotide Polymorphism","authors":"Yu-Rong Yan, Dan Zhao, Qiang Zhang, Yangyang Chang, Meng Liu","doi":"10.1007/s41664-021-00206-8","DOIUrl":"https://doi.org/10.1007/s41664-021-00206-8","url":null,"abstract":"","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"13 1","pages":"53-59"},"PeriodicalIF":4.7,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79270184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-19DOI: 10.1007/s41664-021-00205-9
Xin-yan Wang, Yuanfang Li, Shuzhen Lv, Sai Bi
{"title":"pH-Responsive Magnetic I-Motif Container Coupled with DNA Walker for Construction of Dual-Signal Electrochemical Biosensor","authors":"Xin-yan Wang, Yuanfang Li, Shuzhen Lv, Sai Bi","doi":"10.1007/s41664-021-00205-9","DOIUrl":"https://doi.org/10.1007/s41664-021-00205-9","url":null,"abstract":"","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"6 1","pages":"12 - 19"},"PeriodicalIF":4.7,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84898741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gold nanoparticles (AuNPs) colorimetric assays based on distance-dependent optical characteristics have been widely employed for bioanalysis. However, this assay is not effective for visually detecting low-concentration targets due to the faint color change. Here, we developed a handheld nano-centrifugal device which could separate the crosslinked and non-crosslinked AuNPs. Results showed that the handheld nano-centrifugal device could easily reach more than 6000 r/min within 10 s simply by stretching and tightening the coiled rope in an appropriate rhythm. Further, combined with the CRISPR/Cas12a nucleic acids recognition system, a field-deployable colorimetric platform termed handheld nano-centrifugal device assisted CRISPR/Cas12a (Hand-CRISPR) has been validated. Moreover, clinical diagnostics applications for Epstein-Barr virus (EBV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detection with high sensitivity and accuracy (100% consistency with reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) test results) have been demonstrated. Overall, the Hand-CRISPR platform showed great promise in point-of-care-test (POCT) application, expected to become a powerful supplement to the standard nucleic acid testing method in remote or poverty-stricken areas.
Supplementary information: The online version contains supplementary material available at 10.1007/s41664-022-00232-0.
{"title":"Development of a Handheld Nano-centrifugal Device for Visual Virus Detection.","authors":"Zi-Rong Bi, Meng-Lu Hu, Yong-Zhong Jiang, Er-Hu Xiong, Bo-Wen Shu, Si-Qi Li, Han-Wei Chen, Xiao-Hua Chen, Xiao-Ming Zhou","doi":"10.1007/s41664-022-00232-0","DOIUrl":"https://doi.org/10.1007/s41664-022-00232-0","url":null,"abstract":"<p><p>Gold nanoparticles (AuNPs) colorimetric assays based on distance-dependent optical characteristics have been widely employed for bioanalysis. However, this assay is not effective for visually detecting low-concentration targets due to the faint color change. Here, we developed a handheld nano-centrifugal device which could separate the crosslinked and non-crosslinked AuNPs. Results showed that the handheld nano-centrifugal device could easily reach more than 6000 r/min within 10 s simply by stretching and tightening the coiled rope in an appropriate rhythm. Further, combined with the CRISPR/Cas12a nucleic acids recognition system, a field-deployable colorimetric platform termed handheld nano-centrifugal device assisted CRISPR/Cas12a (Hand-CRISPR) has been validated. Moreover, clinical diagnostics applications for Epstein-Barr virus (EBV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) detection with high sensitivity and accuracy (100% consistency with reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) test results) have been demonstrated. Overall, the Hand-CRISPR platform showed great promise in point-of-care-test (POCT) application, expected to become a powerful supplement to the standard nucleic acid testing method in remote or poverty-stricken areas.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s41664-022-00232-0.</p>","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"6 4","pages":"353-364"},"PeriodicalIF":4.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40696914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01Epub Date: 2022-01-13DOI: 10.1007/s41664-021-00204-w
Yue Hou, Cong-Cong Lv, Yan-Li Guo, Xiao-Hu Ma, Wei Liu, Yan Jin, Bao-Xin Li, Min Yang, Shi-Yin Yao
Point-of-care testing (POCT), as a portable and user-friendly technology, can obtain accurate test results immediately at the sampling point. Nowadays, microfluidic paper-based analysis devices (μPads) have attracted the eye of the public and accelerated the development of POCT. A variety of detection methods are combined with μPads to realize precise, rapid and sensitive POCT. This article mainly introduced the development of electrochemistry and optical detection methods on μPads for POCT and their applications on disease analysis, environmental monitoring and food control in the past 5 years. Finally, the challenges and future development prospects of μPads for POCT were discussed.
{"title":"Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing.","authors":"Yue Hou, Cong-Cong Lv, Yan-Li Guo, Xiao-Hu Ma, Wei Liu, Yan Jin, Bao-Xin Li, Min Yang, Shi-Yin Yao","doi":"10.1007/s41664-021-00204-w","DOIUrl":"https://doi.org/10.1007/s41664-021-00204-w","url":null,"abstract":"<p><p>Point-of-care testing (POCT), as a portable and user-friendly technology, can obtain accurate test results immediately at the sampling point. Nowadays, microfluidic paper-based analysis devices (μPads) have attracted the eye of the public and accelerated the development of POCT. A variety of detection methods are combined with μPads to realize precise, rapid and sensitive POCT. This article mainly introduced the development of electrochemistry and optical detection methods on μPads for POCT and their applications on disease analysis, environmental monitoring and food control in the past 5 years. Finally, the challenges and future development prospects of μPads for POCT were discussed.</p>","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"6 3","pages":"247-273"},"PeriodicalIF":4.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39828985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.1007/s41664-021-00201-z
P. J. Huang, Juewen Liu
{"title":"Signaling Kinetics of DNA and Aptamer Biosensors Revealing Graphene Oxide Surface Heterogeneity","authors":"P. J. Huang, Juewen Liu","doi":"10.1007/s41664-021-00201-z","DOIUrl":"https://doi.org/10.1007/s41664-021-00201-z","url":null,"abstract":"","PeriodicalId":14935,"journal":{"name":"Journal of Analysis and Testing","volume":"763 1","pages":"20 - 27"},"PeriodicalIF":4.7,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76919839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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