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Journal of Ayub Medical College, Abbottabad : JAMC最新文献

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12 Month's Assessment Of Clinical Efficacy Of Resin Modified Glass Ionomer Cement And Flowable Composites In Restoration Of Non-Carious Cervical Lesions, A Randomized Clinical Trial. 一项随机临床试验:树脂改性玻璃离聚体水泥和可流动复合材料修复非龋齿宫颈病变12个月的临床疗效评估。
Q3 Medicine Pub Date : 2023-02-01 DOI: 10.55519/JAMC-01-10780
Atikah Saghir, Tehmina Rehman, Bushra Irum, Zarah Afreen, Faisal Nawaz Nawaz

Background: The objective of this study was to compare the clinical efficacy of Resin modified glass ionomer cement and Flowable composite in terms of retention, marginal adaptation and surface texture using United States Public Health Service criteria in non-carious cervical lesions measured over a period of one year.

Methods: A Randomized Clinical Trial is conducted with Informed consent on 60 patients who are randomly allocated into 2 groups with at least 2 Non Carious Cervical Lesions in each. Group 1 is used for Flowable Composite while group 2 is used for resin modified glass ionomer cement. A recall is maintained to draw conclusions between two materials in terms of occurrence of marginal adaptation, retention and surface texture, to show which material is superior to other.

Results: Out of 30 restorations in 12 months follow up, only 19 found to be present in flowable composite group while in resin modified glass ionomer cement group, 28 are retained. Regarding margin integrity, Group 1 showed 21 intact margins whereas 23 margins were intact in group 2, while 18 and 25 showed smooth surface in flowable composite and Resin modified glass ionomer cement group respectively, on exploration.

Conclusion: It can be concluded from our study that Resin modified glass ionomer cement is superior to Flowable composite in terms of retention (p=0.005) and surface texture (p=0.045) in restoration of non carious cervical lesion.

背景:本研究的目的是比较树脂改性玻璃离聚体水泥和可流动复合材料在保留、边缘适应和表面纹理方面的临床疗效,使用美国公共卫生服务标准在一年内测量的非龋齿宫颈病变。方法:在知情同意的情况下,将60例患者随机分为两组,每组至少2例宫颈非恶性病变。第1组用于可流动复合材料,第2组用于树脂改性玻璃离子水泥。通过回忆来得出两种材料在边缘适应、保留和表面纹理方面的结论,以表明哪种材料优于其他材料。结果:随访12个月,30个修复体中,可流动复合材料组仅保留19个,树脂改性玻璃离子水门体组保留28个。在边缘完整性方面,经勘探,第1组有21个边缘完整,第2组有23个边缘完整,可流动复合材料组和树脂改性玻璃离聚体水泥组分别有18个和25个边缘光滑。结论:树脂改性玻璃离聚体水泥在修复宫颈非龋牙病变方面的固位性(p=0.005)和表面质地(p=0.045)均优于可流复合材料。
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引用次数: 1
Comparison Of Outcome Between Open Haemorrhoidectomy Versus Trans-Anal Doppler Guided Hemorrhoidal Artery Ligation With Recto-Anal Repair In 3rd And 4th Degree Haemorrhoids. 开放式痔切除术与经肛门多普勒引导下痔动脉结扎直肠-肛门修复术治疗三、四度痔的疗效比较。
Q3 Medicine Pub Date : 2023-02-01 DOI: 0.55519/JAMC-01-10975
Irfan Saleem, Aqeela Shirazi, Shahid Farooq, Baseer Ullah, Lyba Ghayour, Subtain Haider, Habib Ul Wahab Zia, Muhammad Sarmad Zafar

Background: Haemorrhoids are very common but their exact prevalence is not known as most of the people suffering from them do not seek medical or surgical advice. The literature states their prevalence to be about 39% and commonly affect people aged between 45-65 years of age. Objective of the study was to compare the outcomes of open haemorrhoidectomy Vs Trans anal Doppler ultrasound guided hemorrhoidal artery ligation with recto-anal repair in 3rd and 4th degree haemorrhoids. It was a Randomized control trial, conducted at the Department of Surgery, King Edward Medical University, Lahore; from October 2019 to March 2021.

Methods: This was a randomized control trial study where the results of 70 patients of haemorrhoids including 3rd and 4th degree disease fulfilling the selection criteria, who underwent open haemorrhoidectomy (OH) and Doppler guided haemorrhoidal artery ligation with rectoanal repair (HAL RAR) procedure on elective and emergency operating lists, were analyzed with regards to post-operative pain, bleeding and hospital stay.

Results: From our seventy patients the minimum age was 23 and maximum age limit was 55 years (mean: 35.09±7.47). There were 49 (70%) males and 21 (30%) females. Mean post-op pain on day 7 for OH was 1.12±0.72 and for HAL RAR it was 1.06±0.52. Post-op bleeding (POB) occurred in 4 (10%) patients in OH group and 2(6.66%) patients in HAL RAR group. Mean hospital stay for OH group was 2±0.45 and for HAL RAR it was 1.20±0.40, for POB, it was 1.9±0.30 in OH group and 1.86±0.34 in HAL-RAR group.

Conclusions: There was no significant difference in mean post-op pain on day seven, and post-op bleeding, but there was significant difference in terms of mean hospital stay between the two groups.

背景:痔疮非常常见,但其确切患病率尚不清楚,因为大多数患有痔疮的人不寻求医疗或手术建议。文献表明其患病率约为39%,通常影响年龄在45-65岁之间的人群。本研究的目的是比较开放痔切除术与经肛门多普勒超声引导下痔动脉结扎直肠-肛门修复术治疗3度和4度痔疮的效果。这是一项随机对照试验,在拉合尔爱德华国王医科大学外科学系进行;2019年10月至2021年3月。方法:本研究是一项随机对照试验研究,对70例符合选择标准的3度和4度痔疮患者,在择期和急诊手术名单上接受了开放式痔疮切除术(OH)和多普勒引导下痔动脉结扎直肠肛管修复术(HAL RAR)手术,分析其术后疼痛、出血和住院时间。结果:本组70例患者最小年龄23岁,最大年龄55岁(平均35.09±7.47岁)。男性49例(70%),女性21例(30%)。术后第7天OH患者的平均疼痛为1.12±0.72,HAL RAR患者的平均疼痛为1.06±0.52。OH组术后出血4例(10%),HAL RAR组术后出血2例(6.66%)。OH组平均住院时间为2±0.45,HAL RAR为1.20±0.40,POB组平均住院时间为1.9±0.30,HAL-RAR组平均住院时间为1.86±0.34。结论:两组患者术后第7天的平均疼痛和术后出血无显著差异,但两组患者的平均住院时间有显著差异。
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引用次数: 0
Predictors Of Re-Bleeding After Oesophageal Variceal Banding In Cirrhotic Patients At 4 Weeks. 肝硬化患者食管静脉曲张绑扎术后4周再出血的预测因素。
Q3 Medicine Pub Date : 2023-02-01 DOI: 0.55519/JAMC-01-10722
Shoaib Asghar, Junaid Mustafa, Habib Ur Rehman, Muhammad Kamran Farooq, Muhammad Umar Waheed, Salman Shahid

Background: Acute upper gastrointestinal bleeding is a serious complication in cirrhotic patients. Without recommended management, recurrent bleeding happensin 30-40% within the next 2-3 days, and up to 60% within 1 week. Aim was to determine predictors of re-bleeding after oesophageal variceal banding in cirrhotic patients for 4 weeks. It was a descriptive study, conducted at the Department of Medicine, Sheikh Zayed Hospital, Rahim Yar Khan. Six months from June 21 to December 21, 2021.

Methods: A total of 93patients with active oesophageal variceal bleeding were included in this study. Upper gastrointestinal (UGI) endoscopy was performed to look for bendable varices (grades 1-4) and band ligation was applied. Patients were followed for 4 weeks for the history of hematemesis or Malena, fall in haemoglobin of 2 grams per decilitre or more and endoscopic rebleeding findings.

Results: Out of 93 patients, 67(72.0%) were males, while 26(28.0%) were females. The Mean age of the patients was 45.66±16.61 years. According to Child Pugh Classification, the majority of the patients 45(48.4%) had Child-Pugh Class-A, while 33 (35.5%) were Child B and 15 (16.1%) patients belonged to Child-Pugh Class C. Red wale sign was noted in 22 patients (23.7%). Among 93 cirrhotic patients who presented with variceal bleeding, 9 (9.7%) had re-bleeding within 4 weeks. Amongst 9 patients, 8 patients (88.9%) had red wale sign, grade II or above oesophageal varices and belonged to severe liver disease with child class B or C.

Conclusions: Endoscopic variceal band Ligation is an effective treatment modality for the control of oesophageal variceal bleeding. Re-bleeding after band ligation was 9.7%. The major contributing factors to re-bleeding were the severity of cirrhosis, grades and columns of oesophageal varices, number of bands ligation and findings of red wale sign. Increasing age and duration of cirrhosis were contributing predictors of increased re-bleeding risk.

背景:急性上消化道出血是肝硬化患者的严重并发症。如果没有推荐的治疗方法,30-40%的患者会在接下来的2-3天内再次出血,高达60%的患者会在1周内再次出血。目的是确定肝硬化患者食管静脉曲张绑扎术后4周再出血的预测因素。这是一项描述性研究,在拉希姆亚尔汗谢赫扎耶德医院医学系进行。六个月,从2021年6月21日到12月21日。方法:对93例食管活动性静脉曲张出血患者进行分析。上消化道(UGI)内窥镜检查可弯曲静脉曲张(1-4级),并行绑扎术。对患者进行为期4周的随访,以了解患者是否有呕血史、血红蛋白每分升下降2克或更多以及内镜下再出血的情况。结果:93例患者中,男性67例(72.0%),女性26例(28.0%)。患者平均年龄45.66±16.61岁。Child-Pugh分型:Child-Pugh a级45例(48.4%),Child-Pugh B级33例(35.5%),Child-Pugh c级15例(16.1%),22例(23.7%)出现红槽征。在93例出现静脉曲张出血的肝硬化患者中,9例(9.7%)在4周内再次出血。9例患者中有8例(88.9%)患者有红壁征,食管静脉曲张II级及以上,属于重度肝病伴儿童B级或c级。结论:内镜下静脉曲张结扎是控制食管静脉曲张出血的有效治疗方式。结扎后再出血为9.7%。肝硬化的严重程度、食管静脉曲张的等级和柱状、结扎带的数量和红瓦勒征是导致再出血的主要因素。年龄和肝硬化持续时间的增加是再出血风险增加的预测因素。
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引用次数: 0
Trans Oral Endoscopic Thyroidectomy Vestibular Approach (Toetva), Case Series Of The First Clinical Experience From Pakistan. 经口内窥镜甲状腺切除术前庭入路(Toetva),巴基斯坦首次临床经验病例系列。
Q3 Medicine Pub Date : 2023-02-01 DOI: 10.55519/JAMC-01-10613
Iqra Zakir, Ahmad Nawaz

Background: The objective of the study to assess the workability and cosmetic outcome of endoscopic thyroidectomy vestibular approach (TOETVA) and share results of underdeveloped country with the world about their first clinical experience.

Methods: We performed TOETVA in 3 patients presenting with thyroid nodules in our hospital, between October 2020 and December 2020 at Liaquat National hospital. Three-port technique was used, one 10-mm port for camera and two 5-mm ports for working. All ports were passed through oral vestibule. The demographic data of the patients and surgical outcomes were retrospectively reviewed. The surgery was completed successfully in all 3 patients. The operative time was between 120-150 mins.

Results: No complications such as recurrent laryngeal nerve palsy, mental nerve injury or parathyroid gland injury damage occurred in patients postoperatively. No visible scarring occurred in the patients postoperatively. Patients remain stable after surgery and got discharged next day. No complications were noted in 6 months follow up.

Conclusions: TOETVA is safe, feasible, and effective and scar free option as compared to conventional thyroid surgery.

背景:本研究的目的是评估内窥镜甲状腺切除术前庭入路(TOETVA)的可行性和美容效果,并与世界分享欠发达国家的首次临床经验。方法:我们于2020年10月至2020年12月在Liaquat国立医院对3例甲状腺结节患者进行了TOETVA手术。采用三端口技术,1个10mm端口用于摄像,2个5mm端口用于工作。所有端口均通过口前庭。回顾性分析患者的人口学资料和手术结果。3例患者均成功完成手术。手术时间120 ~ 150分钟。结果:术后无喉返神经麻痹、精神神经损伤、甲状旁腺损伤等并发症发生。术后未见明显瘢痕形成。术后病情稳定,于次日出院。随访6个月无并发症发生。结论:与传统甲状腺手术相比,TOETVA是一种安全、可行、有效、无瘢痕的选择。
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引用次数: 0
Association Of Fibrotic Changes In Liver On Fibro-Scan With Viral Load And Duration Of Hepatitis C Infection -A Pilot Study. 肝纤维化改变与丙型肝炎病毒载量和感染持续时间的相关性初步研究
Q3 Medicine Pub Date : 2023-02-01 DOI: 10.55519/JAMC-01-11171
Muhammad Arshad, Iqra Manzoor, Khalid Hussain Memon, Asif Haider, Umer Aziz Khan, Iraj Nayab, Zareen Fatima

Background: Hepatitis C is a diverse illness that causes significant death and morbidity. The hepatitis C virus infects hundreds of millions of individuals globally (HCV). More than 80% of those infected develop chronic infection; the remaining 10-20% recovers spontaneously through natural immunity. Acute hepatitis is only icteric in 20% of individuals and is seldom severe.

Methods: A pilot study was conducted at INOR hospital Abbottabad. Eleven hepatitis C positive and 10 hepatitis C negative participants were included in the study.

Results: A significant difference correlation was found between viral load and SWE quantification for fibrosis stage in Kilo-Pascal, r=0.904 (p-value=0.000

Conclusions: Although a biopsy is considered to be gold standard for determining the degree of damage caused by chronic viral hepatitis, it is far from perfect. Liver elastography is intriguing techniques that can help physicians make difficult decisions while treating viral hepatitis. This study showed that fibrotic changes of liver are directly proportional to the presence of viral load in blood. The greater the viral load more severe fibrosis will be seen. Age also plays a role in severity of fibrosis, however, more studies on larger population is required to support this statement.

背景:丙型肝炎是一种引起大量死亡和发病率的多种疾病。全球有数亿人感染丙型肝炎病毒(HCV)。80%以上的感染者发展为慢性感染;剩下的10-20%通过自然免疫自行恢复。急性肝炎仅在20%的个体中表现为黄疸,很少严重。方法:在阿伯塔巴德INOR医院进行了一项初步研究。研究中包括11名丙型肝炎阳性和10名丙型肝炎阴性参与者。结果:在Kilo-Pascal中,病毒载量与SWE量化纤维化分期之间存在显著的相关性,r=0.904 (p值=0.000)。结论:虽然活检被认为是确定慢性病毒性肝炎损害程度的金标准,但它还远远不够完美。肝弹性成像是一项有趣的技术,可以帮助医生在治疗病毒性肝炎时做出困难的决定。本研究表明肝脏纤维化的改变与血液中病毒载量的存在成正比。病毒载量越大,纤维化越严重。年龄也在纤维化的严重程度中起作用,然而,需要对更大人群进行更多的研究来支持这一说法。
{"title":"Association Of Fibrotic Changes In Liver On Fibro-Scan With Viral Load And Duration Of Hepatitis C Infection -A Pilot Study.","authors":"Muhammad Arshad,&nbsp;Iqra Manzoor,&nbsp;Khalid Hussain Memon,&nbsp;Asif Haider,&nbsp;Umer Aziz Khan,&nbsp;Iraj Nayab,&nbsp;Zareen Fatima","doi":"10.55519/JAMC-01-11171","DOIUrl":"https://doi.org/10.55519/JAMC-01-11171","url":null,"abstract":"<p><strong>Background: </strong>Hepatitis C is a diverse illness that causes significant death and morbidity. The hepatitis C virus infects hundreds of millions of individuals globally (HCV). More than 80% of those infected develop chronic infection; the remaining 10-20% recovers spontaneously through natural immunity. Acute hepatitis is only icteric in 20% of individuals and is seldom severe.</p><p><strong>Methods: </strong>A pilot study was conducted at INOR hospital Abbottabad. Eleven hepatitis C positive and 10 hepatitis C negative participants were included in the study.</p><p><strong>Results: </strong>A significant difference correlation was found between viral load and SWE quantification for fibrosis stage in Kilo-Pascal, r=0.904 (p-value=0.000 <a=0.05). HCV positive patients showed a viral load of (Mean±SD) 128,185.8±153,719.1.</p><p><strong>Conclusions: </strong>Although a biopsy is considered to be gold standard for determining the degree of damage caused by chronic viral hepatitis, it is far from perfect. Liver elastography is intriguing techniques that can help physicians make difficult decisions while treating viral hepatitis. This study showed that fibrotic changes of liver are directly proportional to the presence of viral load in blood. The greater the viral load more severe fibrosis will be seen. Age also plays a role in severity of fibrosis, however, more studies on larger population is required to support this statement.</p>","PeriodicalId":15141,"journal":{"name":"Journal of Ayub Medical College, Abbottabad : JAMC","volume":"35 1","pages":"110-113"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9367927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment Of Patients Satisfaction Attending Outpatient Departments Of Teaching Hospitals Of Peshawar. 白沙瓦市教学医院门诊病人满意度评价
Q3 Medicine Pub Date : 2023-02-01 DOI: 10.55519/JAMC-01-10914
Liza Khan, Hamna Hidayat, Irum Hussain, Javeria Khan, Huma Ali, Mifrah Rauf Sethi, Muhammad Irfan

Background: The doctor-patient relationship is a central feature of the healthcare system. The recent developments in the delivery of health care have tended to focus on patient satisfaction. Therefore, this study was planned to find out the satisfaction of patients attending the outpatient department of teaching hospitals in Peshawar.

Methods: A cross-sectional study on Patients Satisfaction was conducted in outpatient departments of five different private and public teaching hospitals in Peshawar, Pakistan from March 2019 to March 2020. The questionnaire was translated into Pashto. All the patients consenting to participate were asked questions from Patient Satisfaction Questionnaire-18 (PSQ-18) by the principal investigator. The data was analyzed using SPSS Version 25.

Results: The mean age of the sample (n=1025) was 37.58±15.60 years. There were 725 (70.1%) females and the majority were attending public sector hospitals (n=596, 58.1%). More than half of the sample (n=589, 57.5%) reported higher than mean scores on the Patient Satisfaction Questionnaire (PSQ). The insignificant gender difference was observed in terms of PSQ, whereas patients of public sector hospitals were more satisfied than patients of private sector hospitals (p=0.000). The inter-scale correlation using Pearson Coefficient between patient satisfaction and its subtypes showed a significant moderate positive correlation with a p-value of p=0.000.

Conclusion: More than half of the patients showed satisfaction with the healthcare services. Patients attending public sector hospitals were more satisfied than the patients attending private sector hospitals.

背景:医患关系是医疗保健系统的核心特征。最近在提供保健服务方面的发展趋向于注重病人的满意度。因此,本研究旨在了解白沙瓦市教学医院门诊患者的满意度。方法:对2019年3月至2020年3月在巴基斯坦白沙瓦市5家不同私立和公立教学医院门诊进行患者满意度横断面研究。问卷被翻译成普什图语。所有同意参与的患者均由首席研究员填写患者满意度问卷-18 (PSQ-18)。使用SPSS Version 25对数据进行分析。结果:1025例患者的平均年龄为37.58±15.60岁。共有725名(70.1%)女性,其中大多数在公立医院就诊(n=596名,58.1%)。超过一半的样本(n=589, 57.5%)报告患者满意度问卷(PSQ)得分高于平均水平。在PSQ方面,性别差异不显著,而公立医院患者满意度高于私立医院患者(p=0.000)。采用Pearson系数对患者满意度及其亚型进行量表间相关分析,p值为p=0.000,呈显著的中度正相关。结论:半数以上的患者对医疗服务表示满意。公立医院的病人比私立医院的病人更满意。
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引用次数: 0
Non-Alcoholic Fatty Liver Disease: Physician's Worst Nightmare. 非酒精性脂肪肝:医生的噩梦。
Q3 Medicine Pub Date : 2023-02-01 DOI: 10.55519/JAMC-01-11592
Jibran Umar Ayub Khan, Ayesha Qaisar, Dur -E- Sameen
Fatty liver is nothing new when it comes to gastroenterology practice. In fact it is the most common finding on routine ultrasound scans while performing it for any other clinical indication. We do see a large number of patients having deranged liver function tests undergoing assessment by experienced physicians. Extensive workup is not futile and can add to the satisfaction of the doctor and patient concerned but sometimes it’s exhaustive. There has been a considerable advancement in management of NAFLD; it still remains physician’s worst nightmare especially when there is transformation to full blown cirrhosis and its devastating complications.Obesity, diabetes and hypertriglyceridemia are found inevitably with NAFLD forming metabolic syndrome do add fuel to the fire as far as treating such patients are concerned . They are integral parts of metabolic syndrome which itself can lead to disastrous complications. One of the most vital segments of NAFLD management is weight loss which doesn’t have to be vigorous rather a more steadfast approach with patience is needed. Convincing an obese patient for losing weight is a daunting task as his metabolic demands are entirely different from a normal weight or a thin lean individual.Distinction between Alcoholic Liver Disease and NALFD is not merely based on interpretation of liver function tests. The ALT and AST ratio does help but isn’t definitive. Many physicians do advise abstinence from alcohol as main treatment modality for alcoholic liver disease yet it becomes conspicuously difficult to manage them once the history of alcohol use is for decades. When nothing works, liver biopsy is a last resort showing classical pathological changes for both the diseases. That too requires experienced pathologist and sometime a second examination of the slide is needed as well.There is a need for multi-disciplinary approach for management NALFLD. There needs to be a close collaboration between hepatologist, dieticians and endocrinologists especially in case of metabolic syndrome. Non-alcoholic fatty liver disease (NAFLD) has quite high prevalence of about 25% in western countries. Patients at the greatest risk are those with obesity and type 2 diabetes mellitus. In 2019 the American Diabetes Association guidelines called, for the first time, for clinicians to screen for steato hepatitis and fibrosis all patients with type 2 diabetes and liver steatosis or abnormal plasma amino transferees. Merely screening isn’t enough. Rather more robust approach is required with target oriented results.The choice of treatment and sound clinical judgement will matter a lot. Weight loss in combination with antidiabetic drugs Iike pioglitazone have been found to reverse fibrosis and slow down the progression of disease. The role of vitamin E is also of paramount importance. The biggest dilemma is that patient with NALFD are symptomatic in the beginning with no clues whatsoever. Early diagnosis and treatment are the keys. It’s a
{"title":"Non-Alcoholic Fatty Liver Disease: Physician's Worst Nightmare.","authors":"Jibran Umar Ayub Khan,&nbsp;Ayesha Qaisar,&nbsp;Dur -E- Sameen","doi":"10.55519/JAMC-01-11592","DOIUrl":"https://doi.org/10.55519/JAMC-01-11592","url":null,"abstract":"Fatty liver is nothing new when it comes to gastroenterology practice. In fact it is the most common finding on routine ultrasound scans while performing it for any other clinical indication. We do see a large number of patients having deranged liver function tests undergoing assessment by experienced physicians. Extensive workup is not futile and can add to the satisfaction of the doctor and patient concerned but sometimes it’s exhaustive. There has been a considerable advancement in management of NAFLD; it still remains physician’s worst nightmare especially when there is transformation to full blown cirrhosis and its devastating complications.\u0000Obesity, diabetes and hypertriglyceridemia are found inevitably with NAFLD forming metabolic syndrome do add fuel to the fire as far as treating such patients are concerned . They are integral parts of metabolic syndrome which itself can lead to disastrous complications. One of the most vital segments of NAFLD management is weight loss which doesn’t have to be vigorous rather a more steadfast approach with patience is needed. Convincing an obese patient for losing weight is a daunting task as his metabolic demands are entirely different from a normal weight or a thin lean individual.\u0000Distinction between Alcoholic Liver Disease and NALFD is not merely based on interpretation of liver function tests. The ALT and AST ratio does help but isn’t definitive. Many physicians do advise abstinence from alcohol as main treatment modality for alcoholic liver disease yet it becomes conspicuously difficult to manage them once the history of alcohol use is for decades. When nothing works, liver biopsy is a last resort showing classical pathological changes for both the diseases. That too requires experienced pathologist and sometime a second examination of the slide is needed as well.\u0000There is a need for multi-disciplinary approach for management NALFLD. There needs to be a close collaboration between hepatologist, dieticians and endocrinologists especially in case of metabolic syndrome. Non-alcoholic fatty liver disease (NAFLD) has quite high prevalence of about 25% in western countries. Patients at the greatest risk are those with obesity and type 2 diabetes mellitus. In 2019 the American Diabetes Association guidelines called, for the first time, for clinicians to screen for steato hepatitis and fibrosis all patients with type 2 diabetes and liver steatosis or abnormal plasma amino transferees. Merely screening isn’t enough. Rather more robust approach is required with target oriented results.\u0000The choice of treatment and sound clinical judgement will matter a lot. Weight loss in combination with antidiabetic drugs Iike pioglitazone have been found to reverse fibrosis and slow down the progression of disease. The role of vitamin E is also of paramount importance. The biggest dilemma is that patient with NALFD are symptomatic in the beginning with no clues whatsoever. Early diagnosis and treatment are the keys. It’s a","PeriodicalId":15141,"journal":{"name":"Journal of Ayub Medical College, Abbottabad : JAMC","volume":"35 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10836133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Afebrile Plasmodium Knowlesi Severe Malaria With A Fatal Outcome. 具有致命后果的发热性诺氏疟原虫严重疟疾。
Q3 Medicine Pub Date : 2023-02-01 DOI: 10.55519/JAMC-01-11418
Chee Yik Chang
{"title":"Afebrile Plasmodium Knowlesi Severe Malaria With A Fatal Outcome.","authors":"Chee Yik Chang","doi":"10.55519/JAMC-01-11418","DOIUrl":"https://doi.org/10.55519/JAMC-01-11418","url":null,"abstract":"","PeriodicalId":15141,"journal":{"name":"Journal of Ayub Medical College, Abbottabad : JAMC","volume":"35 1","pages":"186-187"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10836135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Frequency Of Stone Clearance After Transurethral Fragmentation Of Large Urinary Bladder Calculi Using Pneumatic Swiss Lithoclast. 气压瑞士碎石对经尿道大膀胱结石碎裂后结石清除频率的影响。
Q3 Medicine Pub Date : 2023-02-01 DOI: 0.55519/JAMC-01-10910
Shawana Asad, Bilawal Gul, Mir Jalal-Ud-Din, Sher Ali Khan, Rabeeha Bashir, Hina Rafaqat

Background: Vesical calculi refer to stones in the urinary bladder. The causes of bladder stones include bladder outlet obstruction, neurogenic voiding dysfunction, infection, or foreign bodies. Very rarely, these vesical calculi may reach very large sizes and the largest dimension can sometimes reach 13 centimetres.

Methods: This descriptive cross-sectional study was conducted from 1ST May 2019 to 31st October, 2019 at Institute of Kidney Diseases, Urology Department, Hayatabad Peshawar. 164 patients with vesical stone were included in study. Ultrasound-KUB was used for diagnosis of vesical stone and after informed consent, and they underwent transurethral nephroscopic lithotripsy via the pneumatic Swiss Lithoclast.

Results: Frequency of stone clearance was 96.34%. No statistically significant association of stone clearance was observed with age, gender, number of stones or max dimension of largest stone in the bladder (p>0.05).

Conclusions: Transurethral nephroscopic pneumatic lithotripsy via pneumatic Swiss Lithoclast is safe and effective procedure for treatment of large vesical stones. However, this being the first such study in adults, more data is needed to confirm these findings.

背景:膀胱结石是指膀胱内的结石。膀胱结石的病因包括膀胱出口梗阻、神经源性排尿功能障碍、感染或异物。极少数情况下,这些膀胱结石可达到非常大的尺寸,最大的尺寸有时可达到13厘米。方法:本描述性横断面研究于2019年5月1日至2019年10月31日在白沙瓦哈亚塔巴德泌尿科肾脏疾病研究所进行,纳入164例膀胱结石患者。超声- kub用于诊断膀胱结石,经知情同意后,经尿道肾镜气压瑞士碎石机进行碎石术。结果:结石清除率为96.34%。膀胱结石清除率与年龄、性别、结石数量、膀胱最大结石尺寸无统计学意义(p>0.05)。结论:经尿道肾镜气压碎石是治疗大膀胱结石安全有效的方法。然而,这是第一次在成人中进行这样的研究,需要更多的数据来证实这些发现。
{"title":"Frequency Of Stone Clearance After Transurethral Fragmentation Of Large Urinary Bladder Calculi Using Pneumatic Swiss Lithoclast.","authors":"Shawana Asad,&nbsp;Bilawal Gul,&nbsp;Mir Jalal-Ud-Din,&nbsp;Sher Ali Khan,&nbsp;Rabeeha Bashir,&nbsp;Hina Rafaqat","doi":"0.55519/JAMC-01-10910","DOIUrl":"https://doi.org/0.55519/JAMC-01-10910","url":null,"abstract":"<p><strong>Background: </strong>Vesical calculi refer to stones in the urinary bladder. The causes of bladder stones include bladder outlet obstruction, neurogenic voiding dysfunction, infection, or foreign bodies. Very rarely, these vesical calculi may reach very large sizes and the largest dimension can sometimes reach 13 centimetres.</p><p><strong>Methods: </strong>This descriptive cross-sectional study was conducted from 1ST May 2019 to 31st October, 2019 at Institute of Kidney Diseases, Urology Department, Hayatabad Peshawar. 164 patients with vesical stone were included in study. Ultrasound-KUB was used for diagnosis of vesical stone and after informed consent, and they underwent transurethral nephroscopic lithotripsy via the pneumatic Swiss Lithoclast.</p><p><strong>Results: </strong>Frequency of stone clearance was 96.34%. No statistically significant association of stone clearance was observed with age, gender, number of stones or max dimension of largest stone in the bladder (p>0.05).</p><p><strong>Conclusions: </strong>Transurethral nephroscopic pneumatic lithotripsy via pneumatic Swiss Lithoclast is safe and effective procedure for treatment of large vesical stones. However, this being the first such study in adults, more data is needed to confirm these findings.</p>","PeriodicalId":15141,"journal":{"name":"Journal of Ayub Medical College, Abbottabad : JAMC","volume":"35 1","pages":"50-53"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10792710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome Of The Distal Radius Fractures Managed With Across Wrist External Fixator Vs Buttress Plates. 跨腕外固定架与支撑钢板治疗桡骨远端骨折的疗效比较。
Q3 Medicine Pub Date : 2023-02-01 DOI: 10.55519/JAMC-01-10605
Rahman Ali, Anas Ilyas, Hizbullah Riaz, Umer Faheem, Junaid Khan, Naeem Ahmed, Ahmed Aziz

Background: Distal radius fracture is one of the most common injuries presented to emergency department and can be presented in any age group. In young patients the most common cause is Road Traffic Accident (RTA), while old patient history of fall is the most common cause. Different surgical options are available to treat this injury. This study aims to compare the outcome of volar buttress plate vs across wrist external fixator for Arbeitsgemeinschaft für Osteosynthesefragen (AO) type C2/C3 fracture of the distal radius.

Methods: A retrospective comparative study between July 2020 to June 2021 at Ghurki Trust Teaching Hospital was done and a total of 50 patients who underwent surgical intervention for AO C2/C3 fracture of the distal Radius, were included. The follow-up period was 12 weeks. QuickDASH score was used to find out patient's functional outcomes. Functional outcome was analyzed between the two groups using Mann-Whitney U test, using SPSS version 21.

Results: There was no significant statistical difference between the functional outcome of patients with distal radius fracture treated with across wrist external fixator vs volar buttress plate, in term of QuickDASH score. Furthermore, age and gender also were having no effect on functional outcome in our population.

Conclusions: Across wrist external fixator is a reasonable option for AO C2/C3 type fractures of the distal radius with comparable results with volar buttress plate. It is the procedure of choice in high volume tertiary care hospitals like Gurki Trust Teaching hospital as it saves time, have similar functional outcome score, no need to re-open for removal of implant, less chances of tendon rupture as compared to volar buttress plate for distal radius fracture.

背景:桡骨远端骨折是急诊科最常见的损伤之一,任何年龄段都可能发生。在年轻患者中,最常见的原因是道路交通事故(RTA),而老年患者跌倒史是最常见的病因。治疗这种损伤有不同的手术选择。本研究旨在比较掌侧支撑板与跨腕外固定器治疗桡骨远端Arbeitsgemeinschaft für Osteo-synthesefragen(AO)型C2/C3骨折的疗效。方法:2020年7月至2021年6月在古尔基信托教学医院进行了一项回顾性比较研究,共有50名患者接受了桡骨远端AO C2/C3骨折的手术干预。随访时间为12周。QuickDASH评分用于了解患者的功能结果。使用SPSS 21版Mann-Whitney U检验对两组患者的功能结果进行分析。结果:在QuickDASH评分方面,使用跨腕外固定器治疗桡骨远端骨折的患者与使用掌侧支撑板治疗的桡骨远端骨折患者的功能结果之间没有显著的统计学差异。此外,年龄和性别对我们人群的功能结果也没有影响。结论:跨腕外固定器治疗桡骨远端AO C2/C3型骨折是一种合理的选择,与掌侧支撑钢板疗效相当。这是像Gurki Trust Teaching医院这样的大容量三级护理医院的首选手术,因为与桡骨远端骨折的掌侧支撑板相比,它节省了时间,具有相似的功能结果评分,无需重新开放以移除植入物,肌腱断裂的机会更小。
{"title":"Outcome Of The Distal Radius Fractures Managed With Across Wrist External Fixator Vs Buttress Plates.","authors":"Rahman Ali,&nbsp;Anas Ilyas,&nbsp;Hizbullah Riaz,&nbsp;Umer Faheem,&nbsp;Junaid Khan,&nbsp;Naeem Ahmed,&nbsp;Ahmed Aziz","doi":"10.55519/JAMC-01-10605","DOIUrl":"10.55519/JAMC-01-10605","url":null,"abstract":"<p><strong>Background: </strong>Distal radius fracture is one of the most common injuries presented to emergency department and can be presented in any age group. In young patients the most common cause is Road Traffic Accident (RTA), while old patient history of fall is the most common cause. Different surgical options are available to treat this injury. This study aims to compare the outcome of volar buttress plate vs across wrist external fixator for Arbeitsgemeinschaft für Osteosynthesefragen (AO) type C2/C3 fracture of the distal radius.</p><p><strong>Methods: </strong>A retrospective comparative study between July 2020 to June 2021 at Ghurki Trust Teaching Hospital was done and a total of 50 patients who underwent surgical intervention for AO C2/C3 fracture of the distal Radius, were included. The follow-up period was 12 weeks. QuickDASH score was used to find out patient's functional outcomes. Functional outcome was analyzed between the two groups using Mann-Whitney U test, using SPSS version 21.</p><p><strong>Results: </strong>There was no significant statistical difference between the functional outcome of patients with distal radius fracture treated with across wrist external fixator vs volar buttress plate, in term of QuickDASH score. Furthermore, age and gender also were having no effect on functional outcome in our population.</p><p><strong>Conclusions: </strong>Across wrist external fixator is a reasonable option for AO C2/C3 type fractures of the distal radius with comparable results with volar buttress plate. It is the procedure of choice in high volume tertiary care hospitals like Gurki Trust Teaching hospital as it saves time, have similar functional outcome score, no need to re-open for removal of implant, less chances of tendon rupture as compared to volar buttress plate for distal radius fracture.</p>","PeriodicalId":15141,"journal":{"name":"Journal of Ayub Medical College, Abbottabad : JAMC","volume":"35 1","pages":"32-36"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9739321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Ayub Medical College, Abbottabad : JAMC
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