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Constrictive Pericarditis: An Update on Noninvasive Multimodal Diagnosis. 缩窄性心包炎:无创多模式诊断的最新进展。
IF 0.8 Q4 Medicine Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_61_23
Davide Restelli, Maria Ludovica Carerj, Gianluca Di Bella, Concetta Zito, Cristina Poleggi, Tommaso D'Angelo, Rocco Donato, Giorgio Ascenti, Alfredo Blandino, Antonio Micari, Silvio Mazziotti, Fabio Minutoli, Sergio Baldari, Scipione Carerj

Constrictive pericarditis (CP) is a rare condition that can affect the pericardium after every pericardial disease process and has been described even after SARS-CoV-2 infection or vaccine. In CP, the affected pericardium, usually the inner layer, is noncompliant, constraining the heart to a fixed maximum volume and impairing the diastolic function. This leads to several clinical features, that, however, can be pleomorphic. In its difficult diagnostic workup, noninvasive multimodal imaging plays a central role, providing important morphological and functional data, like the enhanced ventricular interdependence and the dissociation between intrathoracic and intracardiac pressures. An early and proper diagnosis is crucial to set an appropriate therapy, changing the prognosis of patients affected by CP. In this review, we cover in detail the main elements of each imaging technique, after a reminder of pathophysiology useful for understanding the diagnostic findings.

缩窄性心包炎(CP)是一种罕见的疾病,可在各种心包疾病过程后影响心包,甚至在感染 SARS-CoV-2 或接种疫苗后也有报道。在 CP 中,受影响的心包(通常是内层)会失去顺应性,将心脏限制在固定的最大容积内,影响心脏的舒张功能。这导致了多种临床特征,但也可能是多形性的。在其诊断过程中,无创多模态成像发挥了核心作用,提供了重要的形态和功能数据,如心室相互依赖性增强以及胸腔内压和心内压间的分离。早期和正确的诊断对于制定适当的治疗方案、改变 CP 患者的预后至关重要。在这篇综述中,我们将详细介绍每种成像技术的主要内容,然后提醒大家注意有助于理解诊断结果的病理生理学。
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引用次数: 0
Replacement of Ascending Aortic Aneurysm with Anomalous Origin of the Right Coronary Artery: Multidisciplinary Imaging for the Diagnosis. 右冠状动脉起源异常的升主动脉瘤置换术:多学科成像诊断。
IF 0.8 Q4 Medicine Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_37_23
Fabrizio Ceresa, Antonio Micari, Liborio Francesco Mammana, Umberto Maisano, Alessandro Di Carlo, Alfredo Luongo, Francesco Patanè

This case report presents a rare scenario involving a congenital anomaly of the right coronary artery's (RCA) origin in association with an ascending aortic aneurysm. While both anomalies are individually recognized in the literature, their coexistence and potential interplay remain understudied. The aim of this report is to emphasize the challenges and implications associated with such a combination. A 78-year-old male patient with an enlarged ascending aortic aneurysm necessitating surgical intervention was found to have an anomalous origin of the RCA during preoperative coronary angiography, confirmed by computed tomography scan. Transesophageal echocardiography further elucidated the coronary abnormality. Intraoperatively, successful aortic replacement was performed, and careful repositioning of the anomalous right coronary ostium was achieved. This case raises important considerations regarding the potential complications arising from coronary anomalies and their impact on the surgical management of ascending aortic aneurysms. The rarity of this combination limits our understanding of their association, making a multidisciplinary approach crucial for optimal patient care. Further research and comprehensive evaluation of similar cases are necessary to better understand the relationship between coronary anomalies and ascending aortic aneurysms. Such investigations will help in improving treatment strategies and outcomes for patients with these complex conditions.

本病例报告介绍了一种罕见的情况,即右冠状动脉(RCA)起源的先天性异常与升主动脉瘤同时存在。虽然这两种畸形在文献中都已得到确认,但它们的共存和潜在的相互作用仍未得到充分研究。本报告旨在强调这种合并症所带来的挑战和影响。一名 78 岁的男性患者因升主动脉瘤增大而需要手术治疗,在术前冠状动脉造影检查中发现其 RCA 起源异常,并经计算机断层扫描证实。经食道超声心动图进一步证实了冠状动脉的异常。术中成功实施了主动脉置换术,并对异常的右冠状动脉骨膜进行了仔细的重新定位。该病例提出了冠状动脉异常引起的潜在并发症及其对升主动脉瘤手术治疗的影响等重要问题。这种并发症的罕见性限制了我们对其关联性的了解,因此多学科方法对患者的最佳治疗至关重要。为了更好地了解冠状动脉异常和主动脉升主动脉瘤之间的关系,有必要对类似病例进行进一步研究和综合评估。这些研究将有助于改善这些复杂病症患者的治疗策略和疗效。
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引用次数: 0
Can Global Longitudinal Strain Assess Asymptomatic Subtle Left Ventricular Dysfunction in Recovered COVID-19 Patients? 全局纵向应变能否评估 COVID-19 康复患者无症状的细微左心室功能障碍?
IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_6_23
Hazem Mansour, Aly Osama Abdelhady, Walaa Adel Abdel Reheim, Viola William

Background: Coronavirus disease 2019 (COVID-19) might be associated with cardiac injury as a part of multisystem affection in response to cytokine storms. However, left ventricular (LV) function appears preserved in most of the cases, whereas subtle LV dysfunction might happen in others. Hence, we tried to detect subtle LV dysfunction in patients with COVID-19 using global longitudinal strain (GLS).

Patients and methods: We performed a single-center observational study on 90 stable patients who were recently recovered from mild to moderate COVID-19 infections. A transthoracic echocardiographic examination was done for all patients, and GLS assessment was used as an indicator of LV function.

Results: The population age ranged from 27 to 66 years, and the majority of patients were males (54, 73.3%). Besides, 46.7% of the included patients were smokers, 33.3% had hypertension, and 23.3% were diabetics. All the patients had normal LV internal dimensions and ejection fractions. However, 33.3% of them had subclinical LV dysfunction as expressed by reduced GLS. There was no statistically significant correlation between GLS and age, gender, or other risk factors, whereas troponin and C-reactive protein significantly correlated with GLS.

Conclusions: Recovered patients from recent mild to moderate COVID-19 infections might show subtle LV dysfunction as manifested by reduced GLS.

背景:2019年冠状病毒病(COVID-19)可能与心脏损伤有关,是细胞因子风暴引起的多系统疾病的一部分。然而,在大多数病例中,左心室(LV)功能似乎保持不变,而在其他病例中,可能会出现微妙的左心室功能障碍。因此,我们尝试用全局纵向应变(GLS)检测COVID-19患者的细微左心室功能障碍:我们对 90 名刚从轻度至中度 COVID-19 感染中康复的稳定期患者进行了单中心观察研究。所有患者均接受了经胸超声心动图检查,并将 GLS 评估作为左心室功能的指标:患者年龄从 27 岁到 66 岁不等,大多数患者为男性(54 人,占 73.3%)。此外,46.7%的患者吸烟,33.3%患有高血压,23.3%患有糖尿病。所有患者的左心室内径和射血分数均正常。然而,其中33.3%的患者存在亚临床左心室功能障碍,表现为GLS降低。GLS与年龄、性别或其他风险因素之间没有统计学意义上的显著相关性,而肌钙蛋白和C反应蛋白与GLS有显著相关性:结论:近期轻度至中度 COVID-19 感染的康复患者可能会出现微妙的左心室功能障碍,表现为 GLS 降低。
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引用次数: 0
A Case of Late Presentation of Supracardiac Total Anomalous Pulmonary Venous Connection in an Adult. 一例成人心上全肺静脉连接异常的晚期病例
IF 0.8 Q4 Medicine Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_62_23
Avinash Prakash, Ishan Jhalani, Anshuman Darbari, Ajay Kumar

Total anomalous pulmonary venous connection (TAPVC) is a rare cyanotic congenital heart disease and their survival into adulthood is even rarer. Here, we present the case of a 26-year-old female who was incidentally diagnosed with a case of supracardiac TAPVC during her pregnancy. All four pulmonary veins were joining to form a common venous confluence which drained into a left-sided vertical vein which drained into the innominate vein.

全肺静脉连接异常(TAPVC)是一种罕见的紫绀型先天性心脏病,成年后存活的患者更是少之又少。在此,我们介绍了一例 26 岁女性的病例,她在怀孕期间偶然被诊断出患有心上型 TAPVC。所有四条肺静脉汇合成一条共同的静脉汇流口,排入一条左侧垂直静脉,该静脉排入腹股沟静脉。
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引用次数: 0
Catch the Cath or Not? A Hamletic Dilemma after 10 Years. 抓还是不抓?十年后的哈姆雷特困境
IF 0.8 Q4 Medicine Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_68_23
Francesco Natale, Giuseppe Raucci, Riccardo Molinari, Roberta Alfieri, Diego D'Arienzo, Enrica Pezzullo, Francesco S Loffredo, Paolo Golino, Giovanni Cimmino

In the last few years, a tremendous advancement has been made in the therapeutical management of several diseases with an increasing need for parental drug administration. To avoid repeated venous insertions and the patient's anxiety related to these procedures, it is now common practice to insert a catheter to leave it in place for a longer time. However, these procedures may generate some complications, such as failure of insertion, embolization, and infection. Different noninvasive techniques have been proposed and used for the retrieval of lost or misplaced foreign objects. Here, we presented a case of the lost fragmented catheter in a young female who underwent a central venous catheter insertion 10 years ago, incidentally detected during an echocardiographic examination. Here, we presented a case of a lost fragmented catheter in a young female who underwent a central venous catheter insertion 10 years before.

近几年来,随着亲体给药需求的增加,多种疾病的治疗管理也取得了巨大进步。为了避免反复插入静脉和病人对这些过程的焦虑,现在普遍的做法是插入导管并让其在原位停留较长时间。然而,这些程序可能会产生一些并发症,如插入失败、栓塞和感染。人们提出并使用了不同的非侵入性技术来找回丢失或错位的异物。在此,我们介绍了一例在 10 年前接受中心静脉导管插入手术的年轻女性身上丢失的碎片导管,该导管是在超声心动图检查中偶然发现的。在此,我们介绍了一例在 10 年前接受中心静脉导管插入手术的年轻女性中丢失的碎片导管。
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引用次数: 0
Stalactites in the Right Ventricle. 右心室钟乳石
IF 0.8 Q4 Medicine Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_46_23
Eugenio Genovesi, Mario Di Marino, Massimo Di Marco, Sabina Gallina, Kristian Galanti, Leonardo Paloscia

Heart metastatic tumors are more frequent than primary heart tumors. Cardiac metastasis is a rare phenomenon, occurring mainly by direct spread, especially from lung cancer. Cardiac metastases may be asymptomatic or cause arrhythmias, nonspecific electrocardiographic alterations, or mimic a myocardial infarction. In this case report, we illustrate a rare case of pulmonary adenocarcinoma, which through the bloodstream developed a stalactite-shaped metastasis within the right ventricle of conspicuous size (20 mm × 34 mm × 12 mm). In addition, the tumor compressed the right pulmonary trunk, causing pulmonary hypertension. It is essential to characterize metastasis with multimodality imaging. Such lesions within the right cavities can cause massive pulmonary embolism, as in our case, leading to the patient's death, thrombolytic therapy not being effective.

心脏转移性肿瘤比原发性心脏肿瘤更为常见。心脏转移瘤是一种罕见的现象,主要通过直接扩散发生,尤其是肺癌。心脏转移瘤可能没有症状,也可能导致心律失常、非特异性心电图改变或模仿心肌梗死。在本病例报告中,我们展示了一例罕见的肺腺癌病例,该肿瘤通过血液在右心室内形成了一个明显大小(20 毫米 × 34 毫米 × 12 毫米)的钟乳石状转移瘤。此外,肿瘤还压迫了右肺主干,导致肺动脉高压。通过多模态成像确定转移瘤的特征至关重要。右腔内的此类病变可导致大面积肺栓塞,就像我们的病例一样,导致患者因溶栓治疗无效而死亡。
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引用次数: 0
Echocardiography in Simple Congenital Heart Diseases: Guiding Adult Patient Management. 简单先天性心脏病的超声心动图检查:指导成人患者管理。
IF 0.8 Q4 Medicine Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_52_23
Domenico Galzerano, Valeria Pergola, Abdalla Eltayeb, Fulgione Ludovica, Lana Arbili, Loay Tashkandi, Sara Di Michele, Agatella Barchitta, Maurizio Vito Parato, Giovanni Di Salvo

This article provides comprehensive insights into the evaluation of simple congenital heart diseases (CHDs) in adults, emphasizing the pivotal role of echocardiography. By focusing on conditions such as congenital aortic stenosis, aortic coarctation, patent ductus arteriosus, atrial septal defects (ASDs), and ventricular septal defects (VSDs), the review underscores echocardiography's intricate contributions to precise clinical decision-making. Echocardiography serves as the primary imaging modality, offering high-resolution visualization of anatomical anomalies and quantification of hemodynamic parameters. It enables tailored therapeutic strategies through its capacity to discern the dimensions, spatial orientation, and dynamic shunt dynamics of defects such as ASDs and VSDs. Moreover, echocardiography's advanced techniques, such as tissue Doppler imaging and speckle tracking, provide detailed insights into atrial mechanics, diastolic function, and ventricular filling kinetics. Integration of echocardiographic findings into clinical practice empowers clinicians to create personalized interventions based on quantified ventricular function, which spans systolic and diastolic aspects. This approach facilitates risk stratification and therapeutic planning, particularly pertinent in heart failure management within the CHD patient population. In summary, echocardiography transcends its role as an imaging tool, emerging as a precision-guided instrument adept at navigating the complexities of simple CHD in adults. Its ability to expedite diagnosis, quantify hemodynamic impacts, and unravel multifaceted functional dynamics culminates in a comprehensive depiction of these conditions. The fusion of these insights with clinical expertise empowers clinicians to navigate the intricate pathways of CHD, crafting tailored therapeutic strategies characterized by precision and efficacy.

本文全面介绍了成人简单先天性心脏病(CHD)的评估,强调了超声心动图的关键作用。通过重点分析先天性主动脉瓣狭窄、主动脉瓣狭窄、动脉导管未闭、房间隔缺损 (ASD) 和室间隔缺损 (VSD) 等疾病,文章强调了超声心动图对精确临床决策的重要贡献。超声心动图是主要的成像方式,可提供解剖异常的高分辨率可视化和血液动力学参数的量化。超声心动图能够辨别 ASD 和 VSD 等缺损的尺寸、空间方向和动态分流动力学,从而制定有针对性的治疗策略。此外,超声心动图的先进技术,如组织多普勒成像和斑点追踪技术,还能详细了解心房力学、舒张功能和心室充盈动力学。将超声心动图检查结果与临床实践相结合,使临床医生能够根据量化的心室功能(包括收缩和舒张功能)制定个性化的干预措施。这种方法有助于进行风险分层和制定治疗计划,尤其适用于冠心病患者的心力衰竭管理。总之,超声心动图超越了其作为成像工具的角色,成为一种精确制导的仪器,善于驾驭成人简单冠心病的复杂性。超声心动图能够加快诊断、量化血流动力学影响并揭示多方面的功能动态,从而全面描述这些病症。这些洞察力与临床专业知识的融合使临床医生能够驾驭复杂的冠心病路径,制定以精确和有效为特点的定制治疗策略。
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引用次数: 0
There is Nothing More Invisible than the Obvious: A Case Summary and Literature Review. 没有什么比显而易见更无形:案例总结与文献综述》(There is Nothing More Invisible than the Obvious: A Case Summary and Literature Review.
IF 0.8 Q4 Medicine Pub Date : 2023-10-01 Epub Date: 2024-02-26 DOI: 10.4103/jcecho.jcecho_50_23
Michele Alfieri, Umberto Ianni, Michela Molisana, Vito Maurizio Parato

Bioprosthetic valvular failure (BVF) is a pathological entity arising from a variety of conditions affecting prosthetic heart valves. It may present with an extremely varied pattern, and the identification of the exact etiology is vital to provide a prompt and adequate treatment. It is established that infective endocarditis mainly affects patients with intracardiac devices such as pacemakers or prosthetic valves, and it represents one of the principal mechanisms of BVF. Despite its high incidence, clinical presentations may be atypical, and a close monitoring is essential to prevent catastrophic consequences. We present the case of a partial valvular bioprosthesis detachment associated with a newly formed pseudoaneurysm due to a late infective endocarditis occurred after cardiac surgery, initially manifested with negative blood cultures and clinical findings. We also try to set up a literature review of the most common causes of valvular failure and pseudoaneurysm formation.

人工生物瓣膜功能衰竭(BVF)是一种病理现象,由影响人工心脏瓣膜的各种病症引起。它的表现形式多种多样,因此确定确切的病因对于提供及时和适当的治疗至关重要。目前已经确定,感染性心内膜炎主要影响使用心脏起搏器或人工瓣膜等心脏内装置的患者,是导致 BVF 的主要机制之一。尽管感染性心内膜炎的发病率很高,但其临床表现可能并不典型,因此必须对其进行密切监测,以防止灾难性后果的发生。我们介绍了一例心脏手术后因晚期感染性心内膜炎导致部分瓣膜生物假体脱落并伴有新形成的假性动脉瘤的病例,该病例最初表现为血液培养和临床表现均为阴性。我们还试图对瓣膜功能衰竭和假性动脉瘤形成的最常见原因进行文献综述。
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引用次数: 0
Figure-of-eight Artifact in Echocardiography as Evidence of Adequate Amplatzer Occluder Position. 超声心动图中的 "八 "字形伪影可作为 Amplatzer 封堵器位置适当的证据。
IF 0.8 Q4 Medicine Pub Date : 2023-07-01 Epub Date: 2023-11-20 DOI: 10.4103/jcecho.jcecho_24_23
Juliana Pérez-Pinzón, Nelson Leandro Moreno-Ruiz, Jaime Andres Nieto-Zárate
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引用次数: 0
A Rare Case of Isolated Right Ventricular Loeffler's Endocarditis in Primary Hypereosinophilic Syndrome. 原发性嗜酸性粒细胞增多症中孤立性右心室洛夫勒氏心内膜炎的罕见病例
IF 0.8 Q4 Medicine Pub Date : 2023-07-01 Epub Date: 2023-11-20 DOI: 10.4103/jcecho.jcecho_22_23
Laura Padoan, Stefano Coiro, Stefano Sforna, Maurizio Del Pinto, Ketty Savino

Hypereosinophilic syndrome (HES) is a systemic disorder with various manifestations, characterized by hypereosinophilia and caused by primary or secondary conditions. Loeffler's endocarditis (LE) represents a frequent cardiac manifestation of HES, caused by infiltration of the myocardium by eosinophilic cells, which determines endocardial damage, with subsequent inflammation, thrombosis, and fibrosis of either one or both ventricles. The diagnosis of cardiac involvement is based on a multimodality approach (i.e., two-dimensional transthoracic echocardiography [2D-TTE], speckle-tracking echocardiography [STE], and cardiac magnetic resonance [CMR]), with different findings depending on the stage of disease. STE may be useful in the initial phase when traditional imaging techniques may result negative, whereas CMR allows myocardial tissue characterization along with a better definition of the right ventricle. We present a rare case of LE with isolated right ventricular involvement in a patient with HES caused by chronic eosinophilic leukemia with constitutively activated fusion tyrosine kinase on chromosome 4q12, successfully treated with imatinib mesylate.

嗜酸性粒细胞过多综合征(HES)是一种以嗜酸性粒细胞过多为特征的全身性疾病,有多种表现形式,由原发性或继发性疾病引起。洛夫勒心内膜炎(LE)是嗜酸性粒细胞增多综合征的一种常见心脏表现,由嗜酸性粒细胞浸润心肌引起,导致心内膜损伤,继而引起一侧或双侧心室炎症、血栓形成和纤维化。心脏受累的诊断基于多模式方法(即二维经胸超声心动图[2D-TTE]、斑点追踪超声心动图[STE]和心脏磁共振[CMR]),根据疾病的不同阶段有不同的结果。当传统成像技术可能导致阴性结果时,STE 在初期阶段可能很有用,而 CMR 则可以确定心肌组织的特征,并更好地界定右心室。我们介绍了一例罕见的LE伴孤立右心室受累病例,患者患有慢性嗜酸性粒细胞白血病(HES),该病由染色体4q12上的酪氨酸激酶组成性激活融合引起,甲磺酸伊马替尼治疗成功。
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引用次数: 0
期刊
Journal of Cardiovascular Echography
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