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A Case Report of Aortic Intramural Hematoma: From Diagnosis to Endovascular Treatment Guided by Transesophageal Echocardiography. 主动脉壁内血肿病例报告:在经食道超声心动图引导下,从诊断到血管内治疗。
IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-04-01 Epub Date: 2024-06-28 DOI: 10.4103/jcecho.jcecho_21_24
Giovanni Benedetti, Giancarlo Trimarchi, Cataldo Palmieri, Umberto Paradossi, Sergio Berti, Antonio Rizza

Aortic intramural hematoma (IMH) accounts for approximately 10%-25% of acute aortic syndromes (AAS), and multi-slice computed tomography and magnetic resonance imaging are the leading techniques for diagnosis and classification. In this context, endovascular strategies provide a valid alternative to traditional open surgery and transesophageal echocardiography (TEE) could play a role in therapeutic decision-making and in endovascular repair procedure guidance. A 57-year-old female patient with IMH extending from the left subclavian artery to the upper tract of the abdominal aorta, underwent endovascular aortic repair using an unibody single-branched stent grafting in the aortic arch and descending aorta with a side branch inserted in the left common carotid artery. To restore proper flow in the left axillary artery, a carotid-subclavian bypass graft was performed. The procedure was guided by angiography and TEE. Intraoperative TEE revealed aortic IMH with a significant fluid component in the middle tunic of the aorta with a wall thickness of over 13 mm. TEE was useful in monitoring of all steps of the procedure, showing the presence of the guidewires into the true lumen, the advancement of the prosthesis, and the phases of release and anchoring. This case highlights the importance of using multimodality imaging techniques to evaluate AAS and demonstrates the growing potential of TEE in guiding endovascular repairs.

主动脉壁内血肿(IMH)约占急性主动脉综合征(AAS)的 10%-25%,多层计算机断层扫描和磁共振成像是诊断和分类的主要技术。在这种情况下,血管内治疗策略是传统开放手术的有效替代方案,而经食道超声心动图(TEE)可在治疗决策和血管内修复手术指导中发挥作用。一名 57 岁的女性患者患有从左锁骨下动脉延伸至腹主动脉上段的 IMH,她接受了主动脉内血管修复术,在主动脉弓和降主动脉处使用了单体单支支架移植术,并在左颈总动脉处插入了侧支。为了恢复左侧腋动脉的正常血流,进行了颈动脉-锁骨下旁路移植手术。手术是在血管造影和 TEE 的指导下进行的。术中 TEE 显示主动脉 IMH,主动脉中膜有大量液体成分,壁厚超过 13 毫米。TEE 有助于监测手术的所有步骤,显示导丝是否进入真腔、假体的推进以及释放和锚定阶段。该病例强调了使用多模态成像技术评估 AAS 的重要性,并展示了 TEE 在指导血管内修复方面日益增长的潜力。
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引用次数: 0
Rates and Predictors of Structural Valve Degeneration and Failure of Trifecta Bioprosthetic Valve Over a 5-year Follow-up Period: A Single-center Experience. 5年随访期间Trifecta生物人工瓣膜结构性瓣膜退化和失效的比率和预测因素:单中心经验。
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_74_23
Anas Mohamad Hashem, Ahmed Elkhapery, Amr Mohamed, Rupinder Buttar, Amani Khalouf, Mohamed Salah Mohamed, Faiz Abbas, Saif Ur Rehman, Mahmoud Eisa, Bipul Baibhav, Devesh Rai, Jeremiah P Depta

Introduction: The Trifecta bioprosthetic valve has been commonly used for surgical aortic valve replacement (SAVR). Multiple studies have been done to define the rate of structural valve degeneration (SVD) and failure (SVF), but the outcomes are still debatable. Therefore, we aim to conduct this single-center study to estimate the rate and predictors of SVD/SVF.

Methodology: This retrospective observational cohort single-center study was conducted between 2014 and 2019 among Trifecta SAVR patients. Data were patient's characteristics collected from electronic medical records at baseline and follow-up (3-5 years). Statistical analysis was performed with a significance level of P ≤ 0.05.

Results: A total of 271 eligible patients were identified. Most of our sample were males (57.9%), with a mean age of 71.1 ± 10.6 years. The mean baseline preoperative ejection fraction (EF) was 53.0%, with no change (P = 0.88) in the immediate postoperative EF (53.6%). A most recent follow-up EF revealed a significant increase of EF (55.2%), P = 0.01. Furthermore, there was a significant increase from peak velocity to PVMRE (mean difference [MD] ± standard error of mean (SEM) [0.15 ± 0.04], P < 0.01), an increase in pressure gradient (PGIPE) to PGMRE (MD ± SEM [1.70 ± 0.49], P < 0.01), and a decrease in Doppler velocity index (DVIIPE) to DVIMRE (MD ± SEM [-0.037 ± 0.01], P = 0.01). Regarding the SVF rate, 13 (4.8%) patients had failed valves requiring replacement throughout the study period.

Conclusions: Over a 5-year follow-up period, 4.8% had SVF with an SVD of 23.2%, with the majority of SVD not being clinically significant except in six patients. These results corroborate with a previously published study suggesting a bad clinical outcome of Trifecta valve placement.

简介Trifecta 生物人工瓣膜已被普遍用于外科主动脉瓣置换术(SAVR)。已有多项研究确定了结构性瓣膜退化(SVD)和失败(SVF)的发生率,但结果仍存在争议。因此,我们旨在开展这项单中心研究,以估计 SVD/SVF 的发生率和预测因素:这项回顾性观察队列单中心研究于 2014 年至 2019 年期间在 Trifecta SAVR 患者中进行。数据来源于基线和随访(3-5 年)时的电子病历。统计分析的显著性水平为P≤0.05:结果:共确定了 271 名符合条件的患者。大部分样本为男性(57.9%),平均年龄为(71.1 ± 10.6)岁。术前平均射血分数(EF)为 53.0%,术后EF(53.6%)无变化(P = 0.88)。最近的随访射血分数显示射血分数显著增加(55.2%),P = 0.01。此外,从峰值速度到 PVMRE 有明显增加(平均差 [MD] ± 平均标准误 (SEM) [0.15±0.04],P < 0.01),从压力梯度 (PGIPE) 到 PGMRE 有增加(MD ± SEM [1.70±0.49],P < 0.01),从多普勒速度指数 (DVIIPE) 到 DVIMRE 有减少(MD ± SEM [-0.037±0.01],P = 0.01)。在 SVF 率方面,13 例(4.8%)患者在整个研究期间出现瓣膜故障,需要更换瓣膜:结论:在为期 5 年的随访中,4.8% 的患者出现 SVF,SVD 为 23.2%,除 6 名患者外,大多数 SVD 无临床意义。这些结果与之前发表的一项研究结果相吻合,该研究结果表明,Trifecta 瓣膜置入术的临床效果不佳。
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引用次数: 0
Comparison of Global Longitudinal Strain in Dual-chamber versus Ventricular Pacemaker in Complete Heart Block. 完全性心脏传导阻滞时双腔起搏器与心室起搏器的整体纵向应变比较
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_78_23
Sidhi Laksono, Yoga Yuniadi, Amiliana Mardiani Soesanto, Sunu Budhi Raharjo, Lisnawati, Saptawati Bardosono, Irwan Surya Angkasa, Cliffian Hosanna

Context: Bradycardia caused by total atrioventricular block (TAVB) is treated by implantation of permanent pacemakers (PPMs) in either dual-chamber (DDD) versus ventricular (VVI) pacing modes. DDD is considered a more physiological pacing mode than VVI as it avoids atrioventricular dyssynchrony. However, previous trials have failed to demonstrate the superiority of DDD in improving quality of life and morbidity.

Aims: This study aims to provide postpacemaker function of the left ventricle (LV) measured with global longitudinal strain (GLS), in TAVB patients.

Settings and design: This is a comparative study; samples included in the study are adult TAVB patients undergoing PPM implantation, without significant heart function, and structural abnormality. Echocardiographic parameters are obtained before, after 1 month, and after 3 months post-PPM.

Subjects and methods: A total of 98 TAVB patients undergoes PPM implantation during the study period, 55 patients were excluded, and in the end, only 43 patients fulfill the inclusion criteria.

Statistical analysis used: Baseline data between DDD and VVI are compared using unpaired t-test. Statistical significance 1 month post-PPM and 3 months post-PPM is analyzed using paired t-test.

Results: There were no significant differences between both groups at baseline. However, significant GLS changes are observed 1 month after PPM in the VVI group (P = 0.002), but no significant change was observed in the DDD group even after 3 months (P = 0.055).

Conclusions: In our study, we conclude that DDD is superior in maintaining LV function in the short term in TAVB patients after PPM implantation.

背景:治疗全房室传导阻滞(TAVB)引起的心动过缓的方法是植入双腔(DDD)或心室(VVI)起搏模式的永久起搏器(PPM)。DDD 被认为是一种比 VVI 更符合生理的起搏模式,因为它可以避免房室不同步。目的:本研究旨在提供使用全纵向应变(GLS)测量的 TAVB 患者左心室(LV)起搏器后功能:这是一项比较研究;研究样本为接受 PPM 植入术的成年 TAVB 患者,无明显心功能和结构异常。研究对象和方法: 共有 98 名 TAVB 患者接受了 PPM 植入术:研究期间共有 98 名 TAVB 患者接受了 PPM 植入术,其中 55 名患者被排除在外,最终只有 43 名患者符合纳入标准:采用非配对 t 检验比较 DDD 和 VVI 的基线数据。PPM后1个月和3个月的统计意义采用配对t检验:结果:两组在基线上没有明显差异。然而,PPM 后 1 个月,VVI 组的 GLS 有明显变化(P = 0.002),但 DDD 组即使在 3 个月后也没有明显变化(P = 0.055):结论:在我们的研究中,我们得出结论,DDD 在短期内维持 PPM 植入术后 TAVB 患者的左心室功能方面更具优势。
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引用次数: 0
A Case Report of an Unusual Acute Intramural Hematoma Disguise as Pulmonary Embolism. 伪装成肺栓塞的异常急性硬膜内血肿病例报告
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_77_23
Marco Dell'Uomo, Serenella Conti, Federica Di Meo, Marcello Dominici, Valentino Borghetti

Aortic intramural hematoma (IMH) is characterized by an aortic wall hematoma without intimal flap and it is a variant of acute aortic syndromes (AAS). This entity may represent 10%-25% of the AAS involving the ascending aorta and aortic arch (Stanford Type A) in 10%-30% of cases and the descending thoracic aorta (Stanford Type B) in 60%-70% of cases. IMH impairs the aortic wall and may progress to either inward disruption of the intima, which finally induces typical dissection or outward rupture of the aorta. The literature describes some clinical reports where Type A aortic dissection mimics a pulmonary embolism but is not described as a case provoked by IMH with outward rupture of the aorta.

主动脉壁内血肿(IMH)的特点是主动脉壁血肿而无内膜瓣,是急性主动脉综合征(AAS)的一种变异。这种情况可能占急性主动脉综合征的 10%-25%,10%-30% 的病例涉及升主动脉和主动脉弓(斯坦福 A 型),60%-70% 的病例涉及降胸主动脉(斯坦福 B 型)。IMH 会损害主动脉壁,并可能发展为内膜向内破坏,最终诱发典型的主动脉夹层或主动脉向外破裂。文献描述了一些 A 型主动脉夹层模仿肺栓塞的临床报告,但没有描述 IMH 引起主动脉向外破裂的病例。
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引用次数: 0
Coronary Embolism in Patient with Prosthetic Aortic Valve: Looks Can Be Deceiving. 人工主动脉瓣患者的冠状动脉栓塞:表里不一
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_59_23
Alfredo Mauriello, Beatrice D'Arco, Alfonso Desiderio, Antonello D'Andrea

Coronary embolism is a rare cause of acute coronary syndrome. We report the challenging case of a 68-year-old female with ST-elevation myocardial infarction caused by right main coronary artery embolism in the setting of bioprosthetic aortic valve and previous episode of atrial fibrillation. The management of coronary embolism depends on the patient clinical setting. In this case, the patient has received an implantable loop recorder before discharge to decide the following therapy.

冠状动脉栓塞是急性冠状动脉综合征的罕见病因。我们报告了一例具有挑战性的病例,一名 68 岁的女性患者因右侧冠状动脉主干栓塞导致 ST 段抬高型心肌梗死,当时她正在使用生物人工主动脉瓣,并曾有心房颤动发作。冠状动脉栓塞的治疗取决于患者的临床情况。在本病例中,患者在出院前接受了植入式循环记录器,以决定后续治疗。
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引用次数: 0
Does Speckle Tracking Transthoracic Echocardiography Indicate Subtle Changes in Left Ventricular Function in Heart Failure Patients with Reduced Ejection Fraction Treated by Sacubitril-valsartan? 斑点追踪经胸超声心动图能否显示接受沙奎利-缬沙坦治疗的射血分数降低的心衰患者左心室功能的细微变化?
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_5_24
Amr Setouhi, Osama Nady Mohamed, Hazem M A Farrag, Naser Mohamed Taha, Alaa Ramadan, Hany Taha Askalany

Background: In heart failure patients and reduced ejection fraction (HFrEF), assessing subtle changes in left ventricle (LV) function is crucial for monitoring treatment efficacy. This study aims to determine the effect of valsartan/sacubitril on LV ejection fraction (EF) assessed by two-dimensional (2D) transthoracic echocardiography (TTE) in comparison to that assessed by 2D TTE speckle tracking in patients with HFrEF ≤35% after 6 months of treatment.

Patients and methods: A prospective study will be conducted on 200 heart failure patients with reduced EF (HFrEF) undergoing sacubitril-valsartan treatment. Each participant underwent a comprehensive evaluation, including physical examination, history taking, serial 12-lead electrocardiogram, and 2D echo to evaluate cardiac parameters. In addition, 2D speckle tracking echocardiography (STE) assessments were conducted before and after 6 months of valsartan/sacubitril treatment.

Results: The enrolled patients had an average age of 48 years with 63% females. At the beginning of the study, 9 (4.5%) patients were classified as New York Heart Association (NYHA) FC I, 120 (60%) as NYHA FC II, 64 (32%) as NYHA FC III, and 7 (3.5%) as FC IV. Following treatment, 82 (41%) patients improved to NYHA FC I, and 118 (59%) were in NYHA FC II. Notably, 82 (41%) patients showed improved left ventricular EF (LVEF), detected either by traditional TTE or STE, whereas 118 (59%) showed no improvement in EF through traditional TTE. In addition, 74 (37%) patients demonstrated improvement detected by STE. In contrast, 44 (22%) patients demonstrated no improvement in EF detected by either TTE or STE.

Conclusion: STE was a more reliable diagnostic method for seeing early LVEF improvement in patients with HFrEF receiving valsartan/sacubitril treatment not seen by conventional TTE.

背景:对于射血分数降低(HFrEF)的心力衰竭患者,评估左心室(LV)功能的细微变化对于监测疗效至关重要。本研究旨在确定缬沙坦/沙库比特利对二维(2D)经胸超声心动图(TTE)评估的左心室射血分数(EF)的影响,并与治疗 6 个月后、射血分数≤35% 的 HFrEF 患者通过二维 TTE斑点追踪评估的左心室射血分数(EF)进行比较:一项前瞻性研究将针对200名接受沙库比特利-缬沙坦治疗的EF值降低的心衰患者(HFrEF)。每位参与者都接受了全面评估,包括体格检查、病史采集、连续12导联心电图和二维回波,以评估心脏参数。此外,还在缬沙坦/沙库布利治疗 6 个月前后进行了二维斑点追踪超声心动图(STE)评估:入组患者平均年龄 48 岁,女性占 63%。研究开始时,9 名患者(4.5%)被归类为纽约心脏协会(NYHA)FC I,120 名患者(60%)被归类为 NYHA FC II,64 名患者(32%)被归类为 NYHA FC III,7 名患者(3.5%)被归类为 FC IV。治疗后,82 名(41%)患者的病情好转,达到 NYHA FC I 级,118 名(59%)患者达到 NYHA FC II 级。值得注意的是,通过传统 TTE 或 STE 检测,82 例(41%)患者的左心室 EF(LVEF)有所改善,而 118 例(59%)患者的 EF 没有改善。此外,有 74 例(37%)患者通过 STE 发现左心室 EF 有改善。相比之下,44 例(22%)患者通过 TTE 或 STE 发现 EF 没有改善:结论:STE 是一种更可靠的诊断方法,可发现接受缬沙坦/沙库比普利治疗的 HFrEF 患者早期 LVEF 的改善,而传统 TTE 则无法发现。
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引用次数: 0
Three-dimensional Transesophageal Echocardiography in Infective Endocarditis: What Does It Add? 感染性心内膜炎的三维经食道超声心动图:它能增加什么?
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_80_23
Chiara Sordelli, Sara Hana Weisz, Nunzia Fele, Raffaele Verde, Angela Guarino, Alessandro Perrella, Laura Severino, Corrado Severino, Sergio Severino

Infective endocarditis (IE) diagnosis is based on a clinical suspicion supported by consistent microbiological and instrumental data. Evidence of involvement of cardiac valves (native or prosthetic) or prosthetic intracardiac material is a major diagnostic criterion of IE. Transthoracic echocardiography (TTE) is the initial technique of choice for the diagnosis while transesophageal echocardiography (TEE) is recommended in patients with an inconclusive or negative TTE, in patients with high suspicion of IE, as well as in patients with a positive TTE, in order to document local complications. Repeating TTE and/or TEE should be considered during follow-up of uncomplicated IE, in order to detect new silent complications and monitor vegetation size. In the setting of IE, the role of three-dimensional (3D) TEE is increasing; in fact, this technique has also been shown to be useful for the diagnosis of IE and its complications as it allows to obtain infinite planes and volumetric reconstructions. In this review, we will describe the usefulness of 3D-TEE and its added value in the management of IE.

感染性心内膜炎(IE)的诊断基于临床怀疑,并辅以一致的微生物学和仪器数据。心脏瓣膜(原生瓣膜或人工瓣膜)或人工心内膜受累的证据是 IE 的主要诊断标准。经胸超声心动图(TTE)是初步诊断的首选技术,而经食道超声心动图(TEE)则推荐用于 TTE 未确诊或阴性的患者、高度怀疑 IE 的患者以及 TTE 阳性的患者,以记录局部并发症。在对无并发症的 IE 进行随访时,应考虑重复 TTE 和/或 TEE,以检测新的无声并发症并监测植被的大小。在 IE 的情况下,三维(3D)TEE 的作用越来越大;事实上,这种技术也被证明有助于诊断 IE 及其并发症,因为它可以获得无限平面和容积重建。在这篇综述中,我们将介绍三维 TEE 的实用性及其在 IE 治疗中的附加值。
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引用次数: 0
Unusual Location of a Papillary Fibroelastoma Causing a Multi-territorial Stroke. 位置异常的乳头状纤维母细胞瘤引发多发性中风
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_66_23
Timothy G Scully, Edmond Wong, Timothy Barton, Philip Hayward

A 56-year-old male presented with a multi-territorial stroke without traditional cerebrovascular risk factors. A transesophageal echocardiogram revealed an intracardiac lesion attached to the lateral wall of the left atria, consistent with an atrial myxoma. Surgical excision of the lesion was performed and revealed that lesion was in fact a papillary fibroelastoma with thrombus attached, which demonstrates a novel mechanism by which intracardiac masses can cause cerebral events.

一名 56 岁的男性因多发性中风就诊,没有传统的脑血管风险因素。经食道超声心动图显示,心内病变附着于左心房侧壁,与心房肌瘤一致。手术切除病灶后发现,病灶实际上是一个附有血栓的乳头状纤维母细胞瘤,这证明了心内肿块导致脑事件的一种新机制。
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引用次数: 0
Left Ventricle Noncompaction Phenotype: Cause or Consequence? 左心室不充盈表型:原因还是后果?
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_30_22
Grazia Casavecchia, Matteo Gravina, Francesco Mautone, Maurizio Pesolo, Francesco Mangini, Luca Macarini, Natale Daniele Brunetti

Left ventricular noncompaction (LVNC) is commonly described as a congenital cardiomyopathy characterized by prominent myocardial trabeculae and deep intertrabecular recesses extending in the left ventricular chamber. Clinical presentation can differ considerably from asymptomatic individuals to those presenting with heart failure and other serious complications. Diagnosis is usually made by two-dimensional transthoracic echocardiography or cardiac magnetic resonance. Moreover, even if strain parameters are significantly reduced in patients with LVNC, they are not routinely investigated. Here, we report the case of a previously symptomless patient admitted to the hospital for pulmonary edema. Two-dimensional transthoracic echocardiography showed severe valvular heart disease and left ventricle pronounced trabeculation and remodeling, although speckle tracking echocardiography (STE) demonstrated only mild strain reduction. We, therefore, explore the possibility that STE may be useful to differentiate LVNC cardiomyopathy from LVNC phenotype due to severe remodeling.

左心室不充盈(LVNC)通常被描述为一种先天性心肌病,其特征是突出的心肌小梁和在左心室腔内延伸的深层小梁间凹陷。从无症状到出现心力衰竭和其他严重并发症,临床表现差异很大。诊断通常需要通过二维经胸超声心动图或心脏磁共振检查。此外,即使 LVNC 患者的应变参数明显降低,也没有进行常规检查。在此,我们报告了一例因肺水肿入院的无症状患者。二维经胸超声心动图显示其患有严重的瓣膜性心脏病,左心室有明显的小梁和重塑,但斑点追踪超声心动图(STE)仅显示其应变轻度降低。因此,我们探讨了 STE 可用于区分 LVNC 心肌病和严重重塑导致的 LVNC 表型的可能性。
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引用次数: 0
Severe Regurgitant Bicuspid Aortic Valve in a Patient with Overlapping Left Ventricular Noncompaction and Asymmetrical Septal Hypertrophy. 重叠性左心室不充盈和不对称室间隔肥厚患者的严重反流性双尖瓣主动脉瓣。
IF 0.8 Q4 Medicine Pub Date : 2024-01-01 Epub Date: 2024-04-26 DOI: 10.4103/jcecho.jcecho_4_24
Takehiro Inoue, Takuma Satsu, Hitoshi Kitayama

Overlapping of left ventricular noncompaction (LVNC) and hypertrophic cardiomyopathy in the same patient is rare and is associated with a more severe clinical course and unfavorable prognosis. The present report describes the case of a severely regurgitant bicuspid aortic valve in a 68-year-old man with overlapping LVNC and asymmetrical septal hypertrophy. Aortic valve replacement controlled the left ventricular dilatation that occurred secondary to the volume overload induced by the valvular disease. However, even 3 years postoperatively, severe systolic dysfunction persisted due to the preexisting myocardial disease, requiring close and lifelong follow-up with special attention to life-threatening arrhythmias and thromboembolism.

左心室不充盈(LVNC)和肥厚型心肌病在同一患者中重叠并发的情况非常罕见,而且会导致更严重的临床病程和不利的预后。本报告描述了一例严重反流的双尖瓣主动脉瓣病例,患者是一名 68 岁的男性,患有重叠性 LVNC 和不对称室间隔肥厚。主动脉瓣置换术控制了因瓣膜疾病引起的容量超负荷而继发的左心室扩张。然而,即使在术后 3 年,由于先前存在的心肌疾病,严重的收缩功能障碍依然存在,需要进行密切的终身随访,并特别注意危及生命的心律失常和血栓栓塞。
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引用次数: 0
期刊
Journal of Cardiovascular Echography
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