首页 > 最新文献

Research in Pediatrics & Neonatology最新文献

英文 中文
Posterior Urethral Valve 后尿道瓣膜
Pub Date : 2019-11-25 DOI: 10.31031/RPN.2019.04.000577
N. Alhojaili, A. Alzahrani, I. Kutbi, H. Almalik, S. Ali, M. Yosef
{"title":"Posterior Urethral Valve","authors":"N. Alhojaili, A. Alzahrani, I. Kutbi, H. Almalik, S. Ali, M. Yosef","doi":"10.31031/RPN.2019.04.000577","DOIUrl":"https://doi.org/10.31031/RPN.2019.04.000577","url":null,"abstract":"","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114145618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parents and Early Childhood Professionals Want a Website on Torticollis 家长和幼儿专家需要一个关于斜颈的网站
Pub Date : 2019-11-07 DOI: 10.31031/rpn.2019.03.000575
Kathy T. T. Vu, You Jung Seo, B. Hussey-Gardner
{"title":"Parents and Early Childhood Professionals Want a Website on Torticollis","authors":"Kathy T. T. Vu, You Jung Seo, B. Hussey-Gardner","doi":"10.31031/rpn.2019.03.000575","DOIUrl":"https://doi.org/10.31031/rpn.2019.03.000575","url":null,"abstract":"","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115695414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reversed Differential Cyanosis in Two Neonates with Obstructed Supracardiac Total Anomalous Pulmonary Venous Drainage 2例心上全肺静脉异常引流梗阻新生儿的逆转差异紫绀
Pub Date : 2019-10-21 DOI: 10.31031/rpn.2019.03.000574
Chow Pc, Chen Rhs, Rocha Ba, Yam Nlh
Generalized cyanosis in newborn can be caused by many pathological conditions and cyanotic congenital heart disease represents one of the important causes. Differential cyanosis refers to the situation where upper limb saturation is higher than lower limb and it is well documented to be caused by persistent pulmonary hypertension in newborn (PPHN) [1] or patients with patent ductus arteriosus and Eisenmenger syndrome in adults [2-4]; Table 1. This has been also reported in a neonate with critical aortic stenosis, hypoplastic aortic arch, pulmonary hypertension and PDA [2]. Reversed differential cyanosis (RDC) refers to the situation when the oxygen saturation of upper limb is lower than that of lower limb, which was classically reported in neonates with transposition of great arteries (TGA) with pulmonary hypertension [2] or TGA with aortic arch obstruction or interruption [5-12]; Table 1. Other causes included supracardiac total anomalous pulmonary venous drainage (TAPVD) [13], isolated right subclavian artery [14], and infants on veno-arterial extracorporeal membrane oxygenation using right carotid artery for cannulation [15]. We herewith reported two cases of obstructed supracardiac TAPVD manifested reversed differential cyanosis.
新生儿全身性紫绀可由多种病理条件引起,而先天性紫绀是其重要病因之一。鉴别性紫绀是指上肢饱和度高于下肢的情况,有充分的文献证明是由新生儿(PPHN)[1]或成人动脉导管未闭和艾森曼格综合征患者的持续性肺动脉高压引起的[2-4];表1。这也被报道在新生儿严重主动脉狭窄,主动脉弓发育不全,肺动脉高压和PDA[2]。逆转差性紫绀(RDC)是指上肢氧饱和度低于下肢氧饱和度的情况,主要见于新生儿大动脉转位(TGA)合并肺动脉高压[2]或TGA合并主动脉弓梗阻或中断[5-12];表1。其他原因包括心上全异常肺静脉引流(TAPVD)[13],孤立的右侧锁骨下动脉[14],以及婴儿使用右颈动脉插管行静脉-动脉体外膜氧合[15]。我们在此报告两例心上TAPVD梗阻,表现为不同程度的逆转紫绀。
{"title":"Reversed Differential Cyanosis in Two Neonates with Obstructed Supracardiac Total Anomalous Pulmonary Venous Drainage","authors":"Chow Pc, Chen Rhs, Rocha Ba, Yam Nlh","doi":"10.31031/rpn.2019.03.000574","DOIUrl":"https://doi.org/10.31031/rpn.2019.03.000574","url":null,"abstract":"Generalized cyanosis in newborn can be caused by many pathological conditions and cyanotic congenital heart disease represents one of the important causes. Differential cyanosis refers to the situation where upper limb saturation is higher than lower limb and it is well documented to be caused by persistent pulmonary hypertension in newborn (PPHN) [1] or patients with patent ductus arteriosus and Eisenmenger syndrome in adults [2-4]; Table 1. This has been also reported in a neonate with critical aortic stenosis, hypoplastic aortic arch, pulmonary hypertension and PDA [2]. Reversed differential cyanosis (RDC) refers to the situation when the oxygen saturation of upper limb is lower than that of lower limb, which was classically reported in neonates with transposition of great arteries (TGA) with pulmonary hypertension [2] or TGA with aortic arch obstruction or interruption [5-12]; Table 1. Other causes included supracardiac total anomalous pulmonary venous drainage (TAPVD) [13], isolated right subclavian artery [14], and infants on veno-arterial extracorporeal membrane oxygenation using right carotid artery for cannulation [15]. We herewith reported two cases of obstructed supracardiac TAPVD manifested reversed differential cyanosis.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127435516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship of Blood Prolactin, Cortisol and Thyroid Hormones in Prematural Newborns with Respiratory Distress Syndrome 早产新生儿呼吸窘迫综合征血催乳素、皮质醇和甲状腺激素的关系
Pub Date : 2019-09-24 DOI: 10.31031/RPN.2019.03.000572
E. Yılmaz, B. Yılmaz, D. Firat, Fatih Burak Kaner
Respiratory distress syndrome (RDS) is one of the most common diseases in premature newborns. RDS and related complications are a major cause of mortality and morbidity of premature infants [2]. RDS classically begins in the first 6 hours of life with tachypnea, dyspnea, intercostal retractions, grunting, nasal flaring, and cyanosis. It is a disease characterized by increased oxygen requirement in premature infants. Typical radiological findings accompanied by this clinical picture. There are many etiologic factors, the most important etiological factor is the gestation week. The frequency of RDS increases as gestational age decreases.
呼吸窘迫综合征(RDS)是早产儿最常见的疾病之一。RDS及其并发症是早产儿死亡和发病的主要原因[2]。RDS通常在出生后6小时开始,表现为呼吸急促、呼吸困难、肋间挛缩、咕噜声、鼻肿胀和发绀。这是一种以早产儿需氧量增加为特征的疾病。典型的放射学表现伴临床表现。病因有很多,最重要的病因是妊娠周。RDS的频率随着胎龄的降低而增加。
{"title":"The Relationship of Blood Prolactin, Cortisol and Thyroid Hormones in Prematural Newborns with Respiratory Distress Syndrome","authors":"E. Yılmaz, B. Yılmaz, D. Firat, Fatih Burak Kaner","doi":"10.31031/RPN.2019.03.000572","DOIUrl":"https://doi.org/10.31031/RPN.2019.03.000572","url":null,"abstract":"Respiratory distress syndrome (RDS) is one of the most common diseases in premature newborns. RDS and related complications are a major cause of mortality and morbidity of premature infants [2]. RDS classically begins in the first 6 hours of life with tachypnea, dyspnea, intercostal retractions, grunting, nasal flaring, and cyanosis. It is a disease characterized by increased oxygen requirement in premature infants. Typical radiological findings accompanied by this clinical picture. There are many etiologic factors, the most important etiological factor is the gestation week. The frequency of RDS increases as gestational age decreases.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134058873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Effect of Malnutrition on Mortality in Hospitalized Children 营养不良对住院儿童死亡率的影响
Pub Date : 2019-08-28 DOI: 10.31031/RPN.2019.03.000571
Aida H. Al-Sadeeq
Malnutrition responsible for 45% of deaths among children younger than 5 years in lowand middle-income countries [1,2]. Many studies have reported the individual associations of stunting, wasting, and underweight with mortality [3], However, estimates of the effects of individual anthropometric indicators overlook the fact that multiple deficits may occur simultaneously, especially because all deficits are associated with poverty, poor dietary intake, and infectious diseases [4,5]. This study conducted describe the frequency of undernutrition and to evaluate which types of combined anthropometric deficits carry an increased risk of mortality.
在低收入和中等收入国家,45%的5岁以下儿童死亡是营养不良造成的[1,2]。许多研究报道了发育迟缓、消瘦和体重不足与死亡率之间的个体关联。然而,对个体人体测量指标影响的估计忽略了多种缺陷可能同时发生的事实,特别是因为所有缺陷都与贫困、不良饮食摄入和传染病有关[4,5]。本研究描述了营养不良的频率,并评估了哪种类型的综合人体测量缺陷会增加死亡风险。
{"title":"The Effect of Malnutrition on Mortality in Hospitalized Children","authors":"Aida H. Al-Sadeeq","doi":"10.31031/RPN.2019.03.000571","DOIUrl":"https://doi.org/10.31031/RPN.2019.03.000571","url":null,"abstract":"Malnutrition responsible for 45% of deaths among children younger than 5 years in lowand middle-income countries [1,2]. Many studies have reported the individual associations of stunting, wasting, and underweight with mortality [3], However, estimates of the effects of individual anthropometric indicators overlook the fact that multiple deficits may occur simultaneously, especially because all deficits are associated with poverty, poor dietary intake, and infectious diseases [4,5]. This study conducted describe the frequency of undernutrition and to evaluate which types of combined anthropometric deficits carry an increased risk of mortality.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"2006 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125827762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two ways, one goal: To improve quality of life of people with Diabtes and their family 两种方式,一个目标:改善糖尿病患者及其家人的生活质量
Pub Date : 2019-08-19 DOI: 10.31031/RPN.2019.03.000569
Manuel Vera González, R. Sanchez
{"title":"Two ways, one goal: To improve quality of life of people with Diabtes and their family","authors":"Manuel Vera González, R. Sanchez","doi":"10.31031/RPN.2019.03.000569","DOIUrl":"https://doi.org/10.31031/RPN.2019.03.000569","url":null,"abstract":"","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121588607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Restrictive Versus Liberal Fluid Bolus Therapy in Pediatric Septic Shock: Should It Be Debated 儿童感染性休克的限制性与自由液体治疗:是否应该争论
Pub Date : 2019-08-19 DOI: 10.31031/rpn.2019.03.000570
S. Yuliarto
To date, sepsis has contributed significantly to the child mortality rate, which is around 8.9% in developed countries to 14.2% in developing countries [1-3]. The most common cause of death (23.1-34.6%) was refractory shock [2-4], of which most occured in the first 3 days [5]. An additional hour of persistent shock was associated with >2-fold increased odds of mortality [6]. This shows that early treatment of septic shock is one of the keys to reduce sepsis mortality.
迄今为止,脓毒症是造成儿童死亡率的重要原因,在发达国家约为8.9%,在发展中国家约为14.2%[1-3]。最常见的死亡原因(23.1-34.6%)是难治性休克[2-4],其中大多数发生在前3天[5]。持续休克每增加1小时,死亡率增加2倍以上[6]。可见,早期治疗脓毒症休克是降低脓毒症死亡率的关键之一。
{"title":"Restrictive Versus Liberal Fluid Bolus Therapy in Pediatric Septic Shock: Should It Be Debated","authors":"S. Yuliarto","doi":"10.31031/rpn.2019.03.000570","DOIUrl":"https://doi.org/10.31031/rpn.2019.03.000570","url":null,"abstract":"To date, sepsis has contributed significantly to the child mortality rate, which is around 8.9% in developed countries to 14.2% in developing countries [1-3]. The most common cause of death (23.1-34.6%) was refractory shock [2-4], of which most occured in the first 3 days [5]. An additional hour of persistent shock was associated with >2-fold increased odds of mortality [6]. This shows that early treatment of septic shock is one of the keys to reduce sepsis mortality.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133746600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical Education Vis-A-Vis National Medical Commission in India 医学教育面对面印度国家医学委员会
Pub Date : 2019-08-07 DOI: 10.31031/RPN.2019.03.000568
V. Dandge
{"title":"Medical Education Vis-A-Vis National Medical Commission in India","authors":"V. Dandge","doi":"10.31031/RPN.2019.03.000568","DOIUrl":"https://doi.org/10.31031/RPN.2019.03.000568","url":null,"abstract":"","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130523031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left Gastroschisis Complicated by Dissociation at Gastro-Oesophageal Junction: A Rare Finding 左侧胃裂并发胃-食管交界处分离:罕见的发现
Pub Date : 2019-08-07 DOI: 10.31031/RPN.2019.03.000567
Parveen Kumar, Y. Siddiqui, M. Jajoo
Case Report A 1-day-old neonate with birth weight 1.4kg, born at 36 weeks of gestation, presented to us with left gastroschisis. At presentation, baby was dehydrated and had matted bowel protruding from left abdominal wall defect (Figure 1). After initial resuscitation, baby was taken for emergency operation. She had multiple attempts for difficult intubation. On extending defect of gastroschisis in midline, it revealed nasogastric tube was in peritoneal cavity and there was total dissociation of stomach and oesophagus at gastro-oesophageal junction (GEJ) (Figure 2). There was no other perforation or atresia noted in bowel after warm saline wash and wrapping of matted bowel in warm saline soaked mops. A full thickness primary anastomosis was contemplated, and ventral hernia was created with skin cover as closure of rectus muscles lead to high abdominal pressure (18mmHg). Baby was shifted to neonatal intensive care unit (NICU) and was weaned off ventilator support after two days. The post-operative period was stormy in view of Acinetobacter sepsis and prolonged naos-gastric aspirates. We were able to start slowly infusion feeds and parental nutrition was tapered. Baby was discharged from NICU at one month of age and has been in follow up for one month with present weight of 2.76kg. Abstract A 1-day-old neonate with 1.4kg birth weight, with left sided gastroschisis, complicated by complete dissociation at gastro-oesophageal junction was managed by primary anastomosis and ventral hernia creation. The patient had prolonged post-operative hospital stay in view of sepsis and delayed tolerance of parenteral feeds and doing well in follow up.
病例报告1例1天大的新生儿,出生体重1.4kg,孕36周出生,出现左侧胃裂。入院时,婴儿脱水,左腹壁缺陷突出肠块(图1)。初步复苏后,婴儿被送往紧急手术。她曾多次尝试插管。中线胃裂延伸缺损显示鼻胃管位于腹膜腔内,胃-食管交界处(GEJ)胃与食管完全分离(图2)。经温盐水洗净,用温盐水拖把包裹缠结的肠后,肠内未见其他穿孔或闭锁。考虑进行全层一期吻合,由于直肌闭合导致高腹压(18mmHg),腹部疝被皮肤覆盖。婴儿被转移到新生儿重症监护病房(NICU),两天后停止呼吸机支持。由于不动杆菌脓毒症和长时间的胃-鼻吸液,手术后的时间是暴风雨般的。我们可以开始慢慢地输液,父母的营养逐渐减少。婴儿1月龄从新生儿重症监护病房出院,随访1个月,体重2.76kg。摘要对1日龄新生儿,出生体重1.4kg,左侧胃裂,胃-食管交界处完全分离,采用一期吻合和腹疝术治疗。患者因脓毒症及肠外喂养耐受延迟,术后住院时间延长,随访情况良好。
{"title":"Left Gastroschisis Complicated by Dissociation at Gastro-Oesophageal Junction: A Rare Finding","authors":"Parveen Kumar, Y. Siddiqui, M. Jajoo","doi":"10.31031/RPN.2019.03.000567","DOIUrl":"https://doi.org/10.31031/RPN.2019.03.000567","url":null,"abstract":"Case Report A 1-day-old neonate with birth weight 1.4kg, born at 36 weeks of gestation, presented to us with left gastroschisis. At presentation, baby was dehydrated and had matted bowel protruding from left abdominal wall defect (Figure 1). After initial resuscitation, baby was taken for emergency operation. She had multiple attempts for difficult intubation. On extending defect of gastroschisis in midline, it revealed nasogastric tube was in peritoneal cavity and there was total dissociation of stomach and oesophagus at gastro-oesophageal junction (GEJ) (Figure 2). There was no other perforation or atresia noted in bowel after warm saline wash and wrapping of matted bowel in warm saline soaked mops. A full thickness primary anastomosis was contemplated, and ventral hernia was created with skin cover as closure of rectus muscles lead to high abdominal pressure (18mmHg). Baby was shifted to neonatal intensive care unit (NICU) and was weaned off ventilator support after two days. The post-operative period was stormy in view of Acinetobacter sepsis and prolonged naos-gastric aspirates. We were able to start slowly infusion feeds and parental nutrition was tapered. Baby was discharged from NICU at one month of age and has been in follow up for one month with present weight of 2.76kg. Abstract A 1-day-old neonate with 1.4kg birth weight, with left sided gastroschisis, complicated by complete dissociation at gastro-oesophageal junction was managed by primary anastomosis and ventral hernia creation. The patient had prolonged post-operative hospital stay in view of sepsis and delayed tolerance of parenteral feeds and doing well in follow up.","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123537563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 30 Years Treatise of Allergies and Asthma in Saudi Arabia (1989-2019) 沙特阿拉伯过敏和哮喘30年专著(1989-2019)
Pub Date : 2019-07-03 DOI: 10.31031/RPN.2019.03.000566
S. Hasnain, A. A. Frayh
The scientific and clinical investigations, on both prevalence of allergies and asthma and their possible causative factors in Saudi Arabia, have continued since 1989. Primarily, being a desert country, western scientists and physicians did not believe the existence of a high prevalence of asthma and allergic rhinitis in Saudi Arabia, considering it as a non-specific bronchial hyper reactivity rather than an IgE mediated allergic response to local/regional allergens. In the late 80’s, we started our investigation on prevalence of asthma with an internationally designed questionnaire led by Professor JD Wilson, that time Professor of Clinical Immunology at King Saud University, Riyadh, Saudi Arabia. At the same time, we started indoor and outdoor aeroallergens monitoring program to evaluate the presence and role of various allergens presents in the environment. Our earlier findings were published [115], followed by many other investigators in the country. We continued our investigation and compared the prevalence data from 9 cities which showed an increasing pattern of asthma and allergic rhinitis nationally (Figure 1).
自1989年以来,一直在对沙特阿拉伯的过敏和哮喘患病率及其可能的致病因素进行科学和临床调查。首先,作为一个沙漠国家,西方科学家和医生不相信沙特阿拉伯存在高患病率的哮喘和变应性鼻炎,认为这是一种非特异性支气管高反应性,而不是IgE介导的对局部/区域过敏原的过敏反应。在80年代后期,我们开始了对哮喘患病率的调查用一份国际设计的问卷调查由JD Wilson教授领导,他当时是沙特阿拉伯利雅得沙特国王大学的临床免疫学教授。同时,我们启动了室内和室外空气过敏原监测项目,评估环境中各种过敏原的存在和作用。我们早期的研究结果发表了[115],随后国内许多其他研究者也发表了研究结果。我们继续我们的调查,并比较了9个城市的患病率数据,这些城市显示出全国哮喘和过敏性鼻炎的增加模式(图1)。
{"title":"A 30 Years Treatise of Allergies and Asthma in Saudi Arabia (1989-2019)","authors":"S. Hasnain, A. A. Frayh","doi":"10.31031/RPN.2019.03.000566","DOIUrl":"https://doi.org/10.31031/RPN.2019.03.000566","url":null,"abstract":"The scientific and clinical investigations, on both prevalence of allergies and asthma and their possible causative factors in Saudi Arabia, have continued since 1989. Primarily, being a desert country, western scientists and physicians did not believe the existence of a high prevalence of asthma and allergic rhinitis in Saudi Arabia, considering it as a non-specific bronchial hyper reactivity rather than an IgE mediated allergic response to local/regional allergens. In the late 80’s, we started our investigation on prevalence of asthma with an internationally designed questionnaire led by Professor JD Wilson, that time Professor of Clinical Immunology at King Saud University, Riyadh, Saudi Arabia. At the same time, we started indoor and outdoor aeroallergens monitoring program to evaluate the presence and role of various allergens presents in the environment. Our earlier findings were published [115], followed by many other investigators in the country. We continued our investigation and compared the prevalence data from 9 cities which showed an increasing pattern of asthma and allergic rhinitis nationally (Figure 1).","PeriodicalId":153075,"journal":{"name":"Research in Pediatrics & Neonatology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132550433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Research in Pediatrics & Neonatology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1