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2014 IEEE International Ultrasonics Symposium最新文献

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An improved method of determining peak blood velocity 一种测定峰值血流速度的改进方法
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0559
S. Ricci, D. Vilkomerson, R. Matera, P. Tortoli
The peak blood velocity is used in important diagnostic applications, e.g. for determining the stenosis degree. The peak velocity is typically assessed by detecting the highest frequency in the Doppler spectrum. The selected frequency is then converted to velocity by the Doppler equation. This procedure contains multiple potential sources of error: the peak frequency selection is sensitive to noise and affected by spectral broadening, and the frequency to velocity conversion is altered by the Doppler angle uncertainty. The result is an inaccurate estimate. In this work we propose a new method that removes the aforementioned errors. By exploiting a mathematical model of the Doppler spectrum the exact frequency to be converted to velocity, with no need of broadening compensation, is determined. The angle ambiguity is solved by calculating the Doppler spectra backscattered from two different receive apertures. The proposed methods uses, in transmission and receive, defocused steered waves that produce a wide sample volume. This includes the whole vessel section making the probe positioning quick and easy. The method, validated through Field II simulations and phantom experiments, featured a mean error lower than 1%.
峰值血流速度用于重要的诊断应用,例如确定狭窄程度。峰值速度通常是通过检测多普勒频谱中的最高频率来评估的。然后通过多普勒方程将选定的频率转换为速度。该方法存在多种潜在的误差来源:峰值频率选择对噪声敏感且受频谱展宽的影响,频率与速度的转换受多普勒角不确定性的影响。结果是一个不准确的估计。在这项工作中,我们提出了一种新的方法来消除上述误差。利用多普勒谱的数学模型,确定了在不需要加宽补偿的情况下转换为速度的精确频率。通过计算两个不同接收孔径的后散射多普勒光谱来解决角度模糊问题。所提出的方法在传输和接收中使用产生大样本量的散焦导向波。这包括整个容器部分,使探针定位快速和容易。通过Field II仿真和模拟实验验证,该方法的平均误差低于1%。
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引用次数: 0
Active induction of microbubbles in flow at T-form bifurcation through acoustic focal points with phase variation 通过相位变化的声焦点在t形分叉处主动诱导流动中的微气泡
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0259
K. Masuda, N. Hosaka, R. Koda, Shinya Miyazawa, T. Mochizuki
We have ever reported the method to produce three-dimensional acoustic force field to prevent microbubbles dispersing in flow. However, because produced acoustic force worked only to propel microbubbles in the direction of propagation of ultrasound, there was a limitation in direction to affect the behavior of microbubbles. In this research we examined to produce attractive force toward the transducer by considering phase variation of acoustic field. We used a flat matrix array transducer including 64 PZT elements, which was specially developed to produce a continuous wave. We prepared a T-form bifurcation model as artificial blood vessel, which was difficult to control the course of microbubbles. We produced an acoustic field of two focal points with opposite phase, where the middle of the points covers the bifurcation. As the results, when microbubbles suspension (average diameter of 4 um, density of 2.35 μl/ml) was injected with velocity of 40 mm/s, we confirmed that microbubbles aggregations were produced before reaching the bifurcation point and entered the bifurcation to be propelled to the desired path, where the course of microbubbles corresponded to the middle of the two focal points.
我们曾报道过利用三维声力场防止微气泡在流动中分散的方法。然而,由于产生的声力只对微泡的传播方向起推动作用,因此影响微泡行为的方向是有限的。本文研究了考虑声场相位变化对换能器产生的吸引力。我们使用了包含64个PZT元件的平面矩阵阵列传感器,该传感器是专门为产生连续波而开发的。我们制备了t型分岔模型作为人工血管,微泡的过程难以控制。我们产生了两个相位相反的焦点的声场,其中点的中间覆盖了分岔。结果表明,当微泡悬浮液(平均直径为4 um,密度为2.35 μl/ml)以40 mm/s的速度注入时,我们确认微泡在到达分岔点之前就产生了聚集,并进入分岔点被推进到期望的路径,微泡的过程对应于两个焦点的中间。
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引用次数: 2
Design of a minimally invasive low-frequency microtransducer for ultrasonic neuromodulation 用于超声神经调节的微创低频微换能器的设计
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0100
Amit P. Mulgaonkar, Rahul S. Singh, G. Saddik, Ashkan Maccabi, W. Melega, M. Culjat, W. Grundfest
Studies with low intensity focused ultrasound (LIFU) and other related techniques have recently demonstrated the potential for ultrasound to reversibly modulate neural circuits in a number of different in vivo models. However, accurate acoustic targeting can be complicated by the attenuation and distortion of the acoustic beam during transcranial passage through the cranium. This can potentially complicate basic studies of the effects of targeted ultrasonic neurostimulation. An alternative intervention strategy is to develop ultrasonic neurostimulator probes small enough to be minimally-invasively implanted directly adjacent to target neural structures. Two different configurations of PZT-based low frequency microtransducers were designed, fabricated, and evaluated for such a strategy. Acoustic testing demonstrated evenly collimated acoustic radiation profiles, and a pilot study in a small animal model demonstrated the overall feasibility of this approach.
最近,低强度聚焦超声(LIFU)和其他相关技术的研究表明,超声在许多不同的体内模型中具有可逆调节神经回路的潜力。然而,由于声束在经颅通过头盖骨过程中的衰减和畸变,精确的声定位可能会变得复杂。这可能会使靶向超声神经刺激效果的基础研究复杂化。另一种干预策略是开发足够小的超声神经刺激器探针,以微创方式直接植入目标神经结构附近。针对这一策略,设计、制造并评估了两种不同结构的压电陶瓷低频微换能器。声学测试证明了均匀准直的声辐射剖面,并在小动物模型中进行了初步研究,证明了这种方法的总体可行性。
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引用次数: 0
Full-field characterization of surface vibrations in microacoustic components by supercontinuum laser stroboscopic white-light interferometry 超连续介质激光频闪白光干涉法研究微声元件表面振动的全场表征
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0040
L. Lipiainen, K. Kokkonen, S. Novotny, I. Shavrin, H. Ludvigsen, M. Kaivola
We present phase-sensitive absolute amplitude measurements of surface vibrations in microacoustic devices using a supercontinuum based stroboscopic white-light interferometer. The setup enables full-field characterization of out-of-plane vibration fields down to sub-100 pm amplitudes and up to GHz range, the highest detectable frequency limited only by the duration of the 300 ps light pulses. The capabilities of the system are demonstrated by measuring a vibration field in a square-plate silicon MEMS resonator at a 3.4 MHz resonance. The maximum vibration amplitude was measured to be 40 nm, and a minimum detectable amplitude limit of less than 100 pm was obtained.
我们提出了一种基于超连续介质频闪白光干涉仪的微声器件表面振动的相位敏感绝对振幅测量。该装置可以对面外振动场进行全方位表征,其振幅低至100 pm以下,最高可检测频率仅受300 ps光脉冲持续时间的限制。通过测量3.4 MHz频率的方形硅MEMS谐振器的振动场,验证了该系统的性能。测量到的最大振动幅值为40 nm,最小可检测幅值限制小于100 pm。
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引用次数: 1
In-vivo convex array vector flow imaging 体内凸阵列矢量流成像
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0082
J. Jensen, A. Brandt, M. Nielsen
In-vivo VFI scans obtained from the abdomen of a human volunteer using a convex array transducers and transverse oscillation vector flow imaging (VFI) are presented. A 3 MHz BK Medical 8820e (Herlev, Denmark) 192-element convex array probe is used with the SARUS experimental ultrasound scanner. A sequence with a 129-line B-mode image is followed by a VFI sequence in 17 directions with 32 emissions in each direction. The pulse repetition frequency was set to 5 kHz, and the intensity and MI were measured with the Acoustic Intensity Measurement System AIMS III (Onda, Sunnyvale, California, USA). The derated Ispta.3 was 79.7 mW/m2 and MI was 1.32, which are within FDA limits for abdominal scans. The right liver lobe of a 28-year healthy volunteer was scanned with a view of the main portal vein and vena cava inferior at a frame rate of 7.4 Hz. Thirty frames were acquired, giving 4 seconds of data. For this volunteer the duration corresponded to roughly 3 heartbeats. The velocities were found at a beam-to-flow angle of 72 ± 21°, where a conventional CFM scan would yield poor results. Three VF images from the same position in the cardiac cycle were investigated and the mean lateral velocities were -0.079, -0.081 and -0.080 m/s showing the consistence of the in-vivo results.
使用凸阵列换能器和横向振荡矢量流成像(VFI)从人类志愿者的腹部获得体内VFI扫描。SARUS实验超声扫描仪采用3mhz BK Medical 8820e (Herlev, Denmark) 192单元凸阵列探头。一个序列有129行b模式图像,之后是一个VFI序列在17个方向上,每个方向有32个发射。脉冲重复频率设置为5 kHz,使用声强测量系统AIMS III (Onda, Sunnyvale, California, USA)测量强度和MI。降阶Ispta.3为79.7 mW/m2, MI为1.32,均在FDA对腹部扫描的限制范围内。以7.4 Hz的帧率扫描28岁健康志愿者的右肝叶,观察门静脉主静脉和下腔静脉。采集30帧,给出4秒的数据。对于这个志愿者来说,持续时间大约相当于3次心跳。在流束角为72±21°的情况下,常规CFM扫描的结果很差。研究了心周期同一位置的三幅VF图像,平均横向速度为-0.079,-0.081和-0.080 m/s,显示了体内结果的一致性。
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引用次数: 9
Accurate finite element model of equiaxed-grain engineering material for ultrasonic inspection 等轴晶粒工程材料超声检测的精确有限元模型
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0337
Bo Xiao, R. O’Leary, A. Gachagan, Wenqi Li, T. Burnett
Finite element (FE) simulation of grained material with equiaxed grain distribution is of interest for the virtual prototyping of array structures and the assessment of signal processing algorithms. Construction of such models can be computationally intensive due to the large number of crystallographic orientations required to represent the material. This paper concentrates on analysis and processing of orientation data in order to establish a computationally efficient 2D FE model whilst maintaining appropriate accuracy of the grained structure. Two approaches for orientation processing are proposed and their performances are compared. Parametric studies show that the trade-off between computational overhead and model accuracy will reach the optimal point when Euler space is segmented with a bin size of 15 degree per Euler phase. A transducer array is then incorporated into the FE model to generate B-scan image of the material. The image is compared with experimental equivalent for FE model validation purpose. The minor difference of images proves that the constructed FE model is accurate, highlighting the potential of the proposed methods for application on other equiaxed-grain materials.
具有等轴晶粒分布的颗粒材料的有限元模拟对于阵列结构的虚拟样机和信号处理算法的评估具有重要意义。由于需要大量的晶体学取向来表示材料,因此这种模型的构建可能需要大量的计算。本文主要对定向数据进行分析和处理,以建立计算效率高的二维有限元模型,同时保持颗粒结构的适当精度。提出了两种定位处理方法,并对其性能进行了比较。参数研究表明,当欧拉空间以每个欧拉相位15度的bin大小分割时,计算开销和模型精度之间的权衡将达到最优点。然后将换能器阵列整合到有限元模型中以生成材料的b扫描图像。将图像与实验等效图像进行对比,以验证有限元模型的有效性。图像的微小差异证明了所构建的有限元模型是准确的,突出了所提出的方法在其他等轴晶粒材料上的应用潜力。
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引用次数: 2
Estimation of model parameters characterizing dispersion in ARFI induced shear waves in in vivo human liver ARFI诱导的人体肝脏横波弥散模型参数的估计
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0241
N. Rouze, M. Palmeri, K. Nightingale
We consider the analysis of shear wave dispersion following ARFI excitation in a cohort of 135 Non-Alcoholic Fatty Liver Disease patients traditionally characterized as “difficult-to-image.” Three analysis methods are considered: (1) measuring k(ω) by locating the maximum signal from the two-dimensional Fourier transform (2D-FT) of propagating shear wave data, (2) an extension of this method using model-based sums through 2D-FT data, and (3) shear wave spectroscopy. A linear dispersion model is used to characterize the frequency-dependent phase velocity. The analysis methods are evaluated in terms of robustness as determined by the rate of successful measurements in the patient data, and by the degrees of correlation and bias inherent with each method as determined by viscoelastic FEM validation studies. For these patient data and analysis procedures, although the 2D-FT methods are more robust than the shear wave spectroscopy method, they are also systematically biased. Even so, they can be used can be used to characterize the relative viscoelastic properties of liver.
我们考虑分析135例传统特征为“难以成像”的非酒精性脂肪肝患者ARFI激发后的横波色散。本文考虑了三种分析方法:(1)通过定位传播剪切波数据的二维傅里叶变换(2D-FT)的最大信号来测量k(ω),(2)通过二维傅里叶变换数据使用基于模型的求和对该方法进行扩展,以及(3)剪切波光谱。采用线性色散模型来描述与频率相关的相速度。分析方法是根据稳健性来评估的,这是由患者数据中成功测量的比率决定的,以及由粘弹性有限元验证研究确定的每种方法固有的相关性和偏倚程度来评估的。对于这些患者数据和分析程序,尽管2D-FT方法比剪切波光谱方法更稳健,但它们也存在系统偏差。即便如此,它们仍然可以用来表征肝脏的相对粘弹性。
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引用次数: 3
Acoustic filtering of particles in a flow regime 流态中粒子的声波过滤
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0355
Kristoffer Johansen, Torstein Yddal, S. Kotopoulis, M. Postema
Hydroelectric power is a clean source of energy, providing up to 20% of the World's electricity. Nevertheless, hydroelectric power plants are plagued with a common problem: silt. The silt causes damage to turbine blades, which then require repairing or replacing. In this study, we investigated the possibility to filter micron-sized particles from water using ultrasound. We designed a custom-made flow chamber and performed flow simulations and experiments to evaluate its efficacy. We used a 195-kHz ultrasound transducer operating in continuous-wave mode with acoustic output powers up to 12W. Our acoustic simulations showed that it should be possible to force a 200-μm particle over 2cm in flow, using an acoustic pressure of 12 MPa. Our flow simulations showed, that the fluid flow is not drastically decreased with the flow chamber, which was validated by the experimental measurements. The flow was not reduced when the ultrasound was activated. The acoustic filtering was effective between acoustic powers of 2.6 and 6.4W, where the particle concentration in the clean output was statistically significantly lower than the null experiments.
水力发电是一种清洁能源,提供了世界上20%的电力。然而,水力发电厂面临着一个共同的问题:淤泥。淤泥会损坏涡轮叶片,需要修理或更换。在这项研究中,我们研究了利用超声波从水中过滤微米级颗粒的可能性。我们设计了一个定制的流动室,并进行了流动模拟和实验来评估其效果。我们使用了一个195 khz的超声换能器,工作在连续波模式下,声输出功率高达12W。我们的声学模拟表明,使用12 MPa的声压,应该可以迫使200 μm的颗粒在2cm以上流动。流动模拟结果表明,流体的流量并没有随着流室的增加而急剧减小,实验结果也验证了这一点。当超声波被激活时,流量没有减少。在声功率为2.6 ~ 6.4W时,滤除效果良好,且净输出中颗粒浓度明显低于零实验。
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引用次数: 0
Comparative study of lithium niobate crystal cuts for use as high-voltage acoustic wave sensors 用于高压声波传感器的铌酸锂晶体切割的比较研究
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0493
N. Patel, D. Branch, S. Cular, E. Schamiloglu
A comparison study between Y+36° lithium niobate (LiNbO3) and 0° X-cut LiNbO3 was performed to evaluate the influence of crystal cut on the performance of a piezoelectric high-voltage (HV) sensor. The acoustic wave propagation time was monitored prior to, during, and after applying three different HV source types to the crystal. Direct current (DC), alternating current (AC), and pulsed voltages were used. Data show that the voltage-induced shift in the acoustic wave propagation time scales quadratically for DC and AC voltage for the X-cut crystal. For the Y+36° LiNbO3 crystal, the acoustic wave arrival time scales linearly with DC voltage and quadratically with AC voltage. When applying 5 μs voltage pulses to the crystal, the voltage-induced shift scales linearly with voltage for both crystal cuts. Data suggest LiNbO3 has a frequency sensitive response to voltage and the influence from the crystal cut is significant when applying AC and pulsed voltage to the crystal.
通过Y+36°铌酸锂(LiNbO3)与0°x -切割LiNbO3的对比研究,评价了晶体切割对压电高压(HV)传感器性能的影响。在对晶体施加三种不同的高压源之前、期间和之后,对声波传播时间进行了监测。使用直流(DC)、交流(AC)和脉冲电压。数据表明,在x切割晶体中,电压引起的声波传播时移在直流和交流电压下呈二次尺度变化。对于Y+36°LiNbO3晶体,声波到达时间与直流电压成线性关系,与交流电压成二次关系。当对晶体施加5 μs电压脉冲时,两个晶体切割的电压诱导位移都与电压成线性关系。数据表明,LiNbO3对电压具有频率敏感的响应,当施加交流和脉冲电压时,晶体切割的影响是显著的。
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引用次数: 0
FPGA embedded system for ultrasound particle manipulation with Sonotweezers 基于Sonotweezers的超声粒子操纵FPGA嵌入式系统
Pub Date : 2014-10-23 DOI: 10.1109/ULTSYM.2014.0356
Han Wang, Y. Qiu, C. Démoré, S. Cochran
Recent research in acoustic tweezing has mainly focused on the behaviour of devices for specific applications and the fundamental theories of the forces exerted on the target particles. However, compared to optical tweezers, there have been only limited reports about developments and applications of acoustic tweezers at the system level. This paper outlines a novel design of a multichannel electronics system for ultrasonic particle manipulation applications. The development process of this 16-channel embedded-FPGA ultrasonic signal generation system is described and experimental results are presented based on its use with array-based acoustic tweezing devices (Sonotweezers).
最近对声镊的研究主要集中在特定应用设备的行为和施加在目标粒子上的力的基本理论。然而,与光镊相比,声学镊子在系统级的发展和应用报道有限。本文概述了一种用于超声粒子操纵的多通道电子系统的新设计。介绍了该16通道嵌入式fpga超声信号产生系统的开发过程,并给出了该系统与基于阵列的声镊装置(Sonotweezers)结合使用的实验结果。
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引用次数: 1
期刊
2014 IEEE International Ultrasonics Symposium
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