Pub Date : 2024-04-29DOI: 10.1097/mcg.0000000000002016
Spyridon Zouridis, Daniel Sofia, Osama Alshakhatreh, Madeline Cleary, Omar Daghstani, Paul J Feustel, Maheep Sangha, Seth Richter
The goal of this study is to investigate fecal occult blood test's (FOBT) usage in cases of suspected gastrointestinal bleeding and how it may affect hospitalization length and inpatient endoscopy procedures.
{"title":"Do You Bleed? A 1-Year FOBT Case-Series Study.","authors":"Spyridon Zouridis, Daniel Sofia, Osama Alshakhatreh, Madeline Cleary, Omar Daghstani, Paul J Feustel, Maheep Sangha, Seth Richter","doi":"10.1097/mcg.0000000000002016","DOIUrl":"https://doi.org/10.1097/mcg.0000000000002016","url":null,"abstract":"The goal of this study is to investigate fecal occult blood test's (FOBT) usage in cases of suspected gastrointestinal bleeding and how it may affect hospitalization length and inpatient endoscopy procedures.","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140805057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-24DOI: 10.1097/MCG.0000000000001997
Zhen Yang, Jin Yan, Hai-Sheng Qian, Zi-Hang Zhong, Ruo-Yun Yang, Ke-Dong Li, Han Chen, Yu-Han Zhao, Xin Gao, Zi-Hao Kong, Guo-Xin Zhang, Yun Wang
BACKGROUND There is a lack of sufficient evidence on whether mixed-type differentiated predominant early gastric cancer (MD-EGC) can be treated endoscopically by referring to the criteria for differentiated-type early gastric cancer (EGC). This study aims to evaluate the efficacy of endoscopic submucosal dissection (ESD) in MD-EGC. METHODS Patients with differentiated-type EGC treated with ESD first from January 2015 to June 2021 were reviewed, including MD-EGC and pure differentiated-type EGC (PD-EGC). Clinical data, including the clinicopathological characteristics, resection outcomes of ESD, and recurrence and survival time, were collected, and the difference between MD-EGC and PD-EGC was tested. RESULTS A total of 48 patients (48 lesions) with MD-EGC and 850 patients (890 lesions) with PD-EGC were included. Compared with PD-EGC, MD-EGC had a higher submucosal invasion rate (37.5% vs. 13.7%, P<0.001) and lymphatic invasion rate (10.4% vs. 0.4%, P<0.001). The rates of complete resection (70.8% vs. 92.5%, P<0.001) and curative resection (54.2% vs. 87.4%, P<0.001) in MD-EGC were lower than those of PD-EGC. Multivariate analysis revealed that MD-EGC (OR 4.26, 95% CI, 2.22-8.17, P<0.001) was an independent risk factor for noncurative resection. However, when curative resection was achieved, there was no significant difference in the rates of recurrence (P=0.424) between the 2 groups, whether local or metachronous recurrence. Similarly, the rates of survival(P=0.168) were no significant difference. CONCLUSIONS Despite the greater malignancy and lower endoscopic curative resection rate of MD-EGC, patients who met curative resection had a favorable long-term prognosis.
背景关于混合型分化为主的早期胃癌(MD-EGC)能否参照分化型早期胃癌(EGC)的标准进行内镜治疗,目前还缺乏足够的证据。方法回顾2015年1月至2021年6月首次接受ESD治疗的分化型EGC患者,包括MD-EGC和纯分化型EGC(PD-EGC)。结果共纳入48例MD-EGC患者(48个病灶)和850例PD-EGC患者(890个病灶)。与 PD-EGC 相比,MD-EGC 的粘膜下侵犯率(37.5% 对 13.7%,P<0.001)和淋巴侵犯率(10.4% 对 0.4%,P<0.001)更高。MD-EGC的完全切除率(70.8% vs. 92.5%,P<0.001)和根治性切除率(54.2% vs. 87.4%,P<0.001)均低于PD-EGC。多变量分析显示,MD-EGC(OR 4.26,95% CI,2.22-8.17,P<0.001)是非根治性切除的独立风险因素。然而,在实现治愈性切除后,两组患者的复发率(P=0.424)无显著差异,无论是局部复发还是远期复发。结论尽管MD-EGC恶性程度较高,内镜根治性切除率较低,但达到根治性切除的患者长期预后良好。
{"title":"Endoscopic Submucosal Dissection Criteria for Differentiated-type Early Gastric Cancer Are Applicable to Mixed-type Differentiated Predominant.","authors":"Zhen Yang, Jin Yan, Hai-Sheng Qian, Zi-Hang Zhong, Ruo-Yun Yang, Ke-Dong Li, Han Chen, Yu-Han Zhao, Xin Gao, Zi-Hao Kong, Guo-Xin Zhang, Yun Wang","doi":"10.1097/MCG.0000000000001997","DOIUrl":"https://doi.org/10.1097/MCG.0000000000001997","url":null,"abstract":"BACKGROUND\u0000There is a lack of sufficient evidence on whether mixed-type differentiated predominant early gastric cancer (MD-EGC) can be treated endoscopically by referring to the criteria for differentiated-type early gastric cancer (EGC). This study aims to evaluate the efficacy of endoscopic submucosal dissection (ESD) in MD-EGC.\u0000\u0000\u0000METHODS\u0000Patients with differentiated-type EGC treated with ESD first from January 2015 to June 2021 were reviewed, including MD-EGC and pure differentiated-type EGC (PD-EGC). Clinical data, including the clinicopathological characteristics, resection outcomes of ESD, and recurrence and survival time, were collected, and the difference between MD-EGC and PD-EGC was tested.\u0000\u0000\u0000RESULTS\u0000A total of 48 patients (48 lesions) with MD-EGC and 850 patients (890 lesions) with PD-EGC were included. Compared with PD-EGC, MD-EGC had a higher submucosal invasion rate (37.5% vs. 13.7%, P<0.001) and lymphatic invasion rate (10.4% vs. 0.4%, P<0.001). The rates of complete resection (70.8% vs. 92.5%, P<0.001) and curative resection (54.2% vs. 87.4%, P<0.001) in MD-EGC were lower than those of PD-EGC. Multivariate analysis revealed that MD-EGC (OR 4.26, 95% CI, 2.22-8.17, P<0.001) was an independent risk factor for noncurative resection. However, when curative resection was achieved, there was no significant difference in the rates of recurrence (P=0.424) between the 2 groups, whether local or metachronous recurrence. Similarly, the rates of survival(P=0.168) were no significant difference.\u0000\u0000\u0000CONCLUSIONS\u0000Despite the greater malignancy and lower endoscopic curative resection rate of MD-EGC, patients who met curative resection had a favorable long-term prognosis.","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140659127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-23DOI: 10.1097/mcg.0000000000002009
Jie Zhou, Ye Chen, Songlin Yu, Hui Wang, Yufeng Wang, Quanning Chen
The aim of this study was to evaluate the efficacy, safety, and surgical outcomes of 2-stage management, namely preoperative endoscopic retrograde cholangiopancreatography (ERCP) + laparoscopic cholecystectomy (ERCP+LC) or LC + postoperative ERCP (LC+ERCP), as well as 1-stage management, LC + laparoscopic common bile duct exploration (LCBDE) for treating patients with gallstones and common bile duct stones (CBDS).
{"title":"Comparison of 1-stage and 2-stage Managements for Common Bile Duct Stones and Gallstones (CBDS): A Retrospective Study.","authors":"Jie Zhou, Ye Chen, Songlin Yu, Hui Wang, Yufeng Wang, Quanning Chen","doi":"10.1097/mcg.0000000000002009","DOIUrl":"https://doi.org/10.1097/mcg.0000000000002009","url":null,"abstract":"The aim of this study was to evaluate the efficacy, safety, and surgical outcomes of 2-stage management, namely preoperative endoscopic retrograde cholangiopancreatography (ERCP) + laparoscopic cholecystectomy (ERCP+LC) or LC + postoperative ERCP (LC+ERCP), as well as 1-stage management, LC + laparoscopic common bile duct exploration (LCBDE) for treating patients with gallstones and common bile duct stones (CBDS).","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140636669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-23DOI: 10.1097/mcg.0000000000002013
Jad AbiMansour, Jerry Yung-Lun Chin, Jyotroop Kaur, Eric J Vargas, Barham K Abu Dayyeh, Ryan Law, Vishal Garimella, Michael J Levy, Andrew C Storm, Ross Dierkhising, Alina Allen, Sudhakar Venkatesh, Vinay Chandrasekhara
Endoscopic ultrasound shear wave elastography (EUS-SWE) is a novel modality for liver stiffness measurement. The aims of this study are to evaluate the performance and reliability of EUS-SWE for detecting advanced liver disease in a prospective cohort.
{"title":"Endoscopic Ultrasound-based Shear Wave Elastography for Detection of Advanced Liver Disease.","authors":"Jad AbiMansour, Jerry Yung-Lun Chin, Jyotroop Kaur, Eric J Vargas, Barham K Abu Dayyeh, Ryan Law, Vishal Garimella, Michael J Levy, Andrew C Storm, Ross Dierkhising, Alina Allen, Sudhakar Venkatesh, Vinay Chandrasekhara","doi":"10.1097/mcg.0000000000002013","DOIUrl":"https://doi.org/10.1097/mcg.0000000000002013","url":null,"abstract":"Endoscopic ultrasound shear wave elastography (EUS-SWE) is a novel modality for liver stiffness measurement. The aims of this study are to evaluate the performance and reliability of EUS-SWE for detecting advanced liver disease in a prospective cohort.","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140636899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-23DOI: 10.1097/mcg.0000000000001995
Manu V Venkat, Ling Chen, Jason D Wright, Benjamin Lebwohl
To characterize the frequency and predictors of follow-up endoscopic biopsy in patients with celiac disease.
了解乳糜泻患者进行后续内窥镜活检的频率和预测因素。
{"title":"Prevalence and Predictors of Follow-up Endoscopic Biopsy in Patients With Celiac Disease in the United States.","authors":"Manu V Venkat, Ling Chen, Jason D Wright, Benjamin Lebwohl","doi":"10.1097/mcg.0000000000001995","DOIUrl":"https://doi.org/10.1097/mcg.0000000000001995","url":null,"abstract":"To characterize the frequency and predictors of follow-up endoscopic biopsy in patients with celiac disease.","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140636657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-18DOI: 10.1097/mcg.0000000000002000
Mary White, Rachel Israilevich, Sophia Lam, Michael McCarthy, Vasil Mico, Benjamin Chipkin, Eric Abrams, Kelly Moore, David Kastenberg
We aimed to evaluate whether direct access colonoscopy (DAC) is noninferior to office-scheduled colonoscopy (OSC) for achieving successful colonoscopy.
{"title":"Timely Completion of Direct Access Colonoscopy Is Noninferior to Office Scheduled for Screening and Surveillance.","authors":"Mary White, Rachel Israilevich, Sophia Lam, Michael McCarthy, Vasil Mico, Benjamin Chipkin, Eric Abrams, Kelly Moore, David Kastenberg","doi":"10.1097/mcg.0000000000002000","DOIUrl":"https://doi.org/10.1097/mcg.0000000000002000","url":null,"abstract":"We aimed to evaluate whether direct access colonoscopy (DAC) is noninferior to office-scheduled colonoscopy (OSC) for achieving successful colonoscopy.","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140629282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-16DOI: 10.1097/mcg.0000000000002005
Christian Karime, Miguel Salazar, Cecily N Black, Freddy Caldera, Philip N Okafor, Muhammad B Hammami, Jana G Hashash, Francis A Farraye
Patients with inflammatory bowel disease (IBD) are at increased risk of vaccine-preventable diseases (VPDs). Despite the increasing prevalence of IBD in non-white populations, little is known regarding racial disparities in VPD burden.
{"title":"In Patients With Inflammatory Bowel Disease, Racial Disparities Exist in Burden of Vaccine-preventable Disease Hospitalizations and Outcomes.","authors":"Christian Karime, Miguel Salazar, Cecily N Black, Freddy Caldera, Philip N Okafor, Muhammad B Hammami, Jana G Hashash, Francis A Farraye","doi":"10.1097/mcg.0000000000002005","DOIUrl":"https://doi.org/10.1097/mcg.0000000000002005","url":null,"abstract":"Patients with inflammatory bowel disease (IBD) are at increased risk of vaccine-preventable diseases (VPDs). Despite the increasing prevalence of IBD in non-white populations, little is known regarding racial disparities in VPD burden.","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140576043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-15DOI: 10.1097/MCG.0000000000002008
O. Buldukoglu
{"title":"Potential Future Predictors of Disease Severity and Persistent Organ Failure in Acute Pancreatitis.","authors":"O. Buldukoglu","doi":"10.1097/MCG.0000000000002008","DOIUrl":"https://doi.org/10.1097/MCG.0000000000002008","url":null,"abstract":"","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140699670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-12DOI: 10.1097/mcg.0000000000002001
Yujie Cheng, Lin Yang, Si Xu, Chong Zhang
To investigate the efficacy and safety of vonoprazan based bismuth-containing quadruple therapy (VBCQ) in eradicating Helicobacter pylori (Hp).
研究基于冯诺普拉赞的含铋四联疗法(VBCQ)在根除幽门螺杆菌(Hp)方面的有效性和安全性。
{"title":"Vonoprazan is Not Inferior to Proton Pump Inhibitors in Bismuth-containing Quadruple Therapy for Helicobacter pylori Eradication: A Meta-analysis of 10 Studies From East Asia.","authors":"Yujie Cheng, Lin Yang, Si Xu, Chong Zhang","doi":"10.1097/mcg.0000000000002001","DOIUrl":"https://doi.org/10.1097/mcg.0000000000002001","url":null,"abstract":"To investigate the efficacy and safety of vonoprazan based bismuth-containing quadruple therapy (VBCQ) in eradicating Helicobacter pylori (Hp).","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140576250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-11DOI: 10.1097/mcg.0000000000002007
Akira Folk, Rama Mouhaffel, Harneet Grewal, Sangkyu Noh, Elise Le Cam, Franklin Liu, Sabrina Ho, Macklin Loveland, Enkhsogt Sainbayar, Hoang Nhat Pham, João Paulo Ferreira, Ramzi Ibrahim
US-Mexico (US-MX) border regions are impacted by socioeconomic disadvantages. Alcohol use disorder remains widely prevalent in US-MX border regions, which may increase the risk of alcoholic liver disease (ALD).
{"title":"United States-Mexico Border Disparities in Alcoholic Liver Disease Mortality: A Cross-Sectional Analysis 1999-2020.","authors":"Akira Folk, Rama Mouhaffel, Harneet Grewal, Sangkyu Noh, Elise Le Cam, Franklin Liu, Sabrina Ho, Macklin Loveland, Enkhsogt Sainbayar, Hoang Nhat Pham, João Paulo Ferreira, Ramzi Ibrahim","doi":"10.1097/mcg.0000000000002007","DOIUrl":"https://doi.org/10.1097/mcg.0000000000002007","url":null,"abstract":"US-Mexico (US-MX) border regions are impacted by socioeconomic disadvantages. Alcohol use disorder remains widely prevalent in US-MX border regions, which may increase the risk of alcoholic liver disease (ALD).","PeriodicalId":15457,"journal":{"name":"Journal of clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140576241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}