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MRI and PET/CT of multiple primary hepatic angiosarcomas in 25-year-old man: A case report. 25 岁男子多发性原发性肝血管肉瘤的 MRI 和 PET/CT:病例报告。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_69_2024
Murat Jakipov, Aslan Karimov, Zaukiya Khamitova, Bayram Kochiev, Dauren Bolatov, Zhanat Spatayev, Saltanat Bolsynbekova, Zhuldyz Kuanysh, Dinara Zharlyganova

This study aims to provide a comprehensive understanding of primary hepatic angiosarcoma, a rare and aggressive malignancy, focusing on its diagnostic challenges and unique imaging characteristics. The objective is to delineate the distinctive features of angiosarcoma through computed tomography and magnetic resonance imaging modalities, contributing to improved diagnostic precision and adding valuable insights to the scientific literature. We present the case of a 25-year-old male with primary hepatic angiosarcoma, emphasizing the challenges in distinguishing it from other vascular tumors.

本研究旨在全面了解原发性肝血管肉瘤这种罕见的侵袭性恶性肿瘤,重点关注其诊断难题和独特的成像特征。其目的是通过计算机断层扫描和磁共振成像模式来描述血管肉瘤的独特特征,从而有助于提高诊断的精确性,并为科学文献增添有价值的见解。我们介绍了一例 25 岁男性原发性肝血管肉瘤患者的病例,强调了将其与其他血管肿瘤区分开来所面临的挑战。
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引用次数: 0
Evaluating artificial intelligence's role in lung nodule diagnostics: A survey of radiologists in two pilot tertiary hospitals in China. 评估人工智能在肺结节诊断中的作用:对中国两家试点三级医院放射科医生的调查。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-23 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_72_2024
Weiqi Liu, You Wu, Zhuozhao Zheng, Wei Yu, Mark J Bittle, Hadi Kharrazi

Objectives: This study assesses the perceptions and attitudes of Chinese radiologists concerning the application of artificial intelligence (AI) in the diagnosis of lung nodules.

Material and methods: An anonymous questionnaire, consisting of 26 questions addressing the usability of AI systems and comprehensive evaluation of AI technology, was distributed to all radiologists affiliated with Beijing Anzhen Hospital and Beijing Tsinghua Changgung Hospital. The data collection was conducted between July 19, and 21, 2023.

Results: Of the 90 respondents, the majority favored the AI system's convenience and usability, reflected in "good" system usability scale (SUS) scores (Mean ± standard deviation [SD]: 74.3 ± 11.9). General usability was similarly well-received (Mean ± SD: 76.0 ± 11.5), while learnability was rated as "acceptable" (Mean ± SD: 67.5 ± 26.4). Most radiologists noted increased work efficiency (Mean Likert scale score: 4.6 ± 0.6) and diagnostic accuracy (Mean Likert scale score: 4.2 ± 0.8) with the AI system. Views on AI's future impact on radiology careers varied (Mean ± SD: 3.2 ± 1.4), with a consensus that AI is unlikely to replace radiologists entirely in the foreseeable future (Mean ± SD: 2.5 ± 1.1).

Conclusion: Radiologists at two leading Beijing hospitals generally perceive the AI-assisted lung nodule diagnostic system positively, citing its user-friendliness and effectiveness. However, the system's learnability requires enhancement. While AI is seen as beneficial for work efficiency and diagnostic accuracy, its long-term career implications remain a topic of debate.

研究目的本研究评估了中国放射科医生对人工智能(AI)应用于肺结节诊断的看法和态度:向北京安贞医院和北京清华长庚医院的所有放射科医生发放了一份匿名问卷,其中包括 26 个问题,涉及人工智能系统的可用性和人工智能技术的综合评价。数据收集工作于2023年7月19日至21日进行:结果:在 90 名受访者中,大多数人对人工智能系统的便利性和可用性表示满意,系统可用性量表(SUS)评分为 "良好"(平均值±标准差[SD]:74.3±11.9)。一般可用性同样受到好评(平均值±标准差:76.0 ± 11.5),而可学习性被评为 "可接受"(平均值±标准差:67.5 ± 26.4)。大多数放射科医生指出,人工智能系统提高了工作效率(平均李克特量表得分:4.6 ± 0.6)和诊断准确性(平均李克特量表得分:4.2 ± 0.8)。对于人工智能未来对放射学职业的影响,与会者看法不一(平均值±标准差:3.2±1.4),但一致认为人工智能在可预见的未来不太可能完全取代放射科医生(平均值±标准差:2.5±1.1):结论:北京两家知名医院的放射科医生普遍对人工智能辅助肺结节诊断系统持肯定态度,认为该系统使用方便、效果显著。然而,该系统的可学习性还需要加强。虽然人工智能被认为有利于提高工作效率和诊断准确性,但其对职业生涯的长期影响仍是一个争论的话题。
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引用次数: 0
Acute traumatic subtalar dislocation: A rare but important clinical entity with 15-year retrospective radiological analysis of 23 cases. 急性外伤性踝关节脱位:一种罕见但重要的临床症状,对 23 例病例进行了 15 年的回顾性放射学分析。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_8_2024
King Shing Yung, Hoi Ming Kwok, Nin Yuan Pan, Bill Archie Lo

Objectives: The objectives of this study were to contribute to the limited existing knowledge about subtalar dislocations, analyze the computed tomography (CT) findings and advantages over radiography, and report the rate and potential risk factors of post-traumatic peri-talar osteoarthritis (OA).

Material and methods: A total of 23 cases of traumatic subtalar dislocation during a 15-year period at three regional hospitals were retrospectively reviewed.

Results: All 23 cases were closed dislocations. Successful close reduction was performed in 17 patients (73.9%) and 6 patients (26.1%) required open reduction and internal fixation. Twenty patients (87%) had associated foot and ankle fractures. Fractures of calcaneal medial tubercle were the most common (75%), followed by talar head (30%), sinus tarsi (25%), and medial malleolus (25%). The radiograph's sensitivity for identifying fractures was 48.1%. The mean follow-up period is 30 months. Symptomatic OA affected 8 patients (36.4%). No post-trauatic talar avascular necrosis was noted. Fractures were present in all of those patients with post-traumatic OA (100%). Three out of five patients who sustained high-energy mechanism injury developed radiographic OA (66.7%). Three out of six patients (50%) treated with open reduction and internal fixation also developed radiographic OA.

Conclusion: Subtalar dislocation remains a rare injury. It is strongly associated with foot and ankle fractures. Fractures of the calcaneal medial tubercle were the most common. The risk of post-traumatic symptomatic peritalar OA is high. CT is useful in detecting occult fractures and injured bony subregions. We postulated potential risk factors of post-traumatic OA (fracture, high-energy mechanism of injury, open reduction, and internal fixation); however, this requires further study.

研究目的本研究的目的是为现有有限的关于跖骨下脱位的知识做出贡献,分析计算机断层扫描(CT)的结果和与放射摄影相比的优势,并报告创伤后跖骨周围骨关节炎(OA)的发病率和潜在风险因素:回顾性分析三家地区医院在 15 年间共 23 例创伤性跗骨下脱位病例:结果:所有23例均为闭合性脱位。结果:23 例均为闭合性脱位,其中 17 例(73.9%)成功进行了闭合复位,6 例(26.1%)需要进行开放复位和内固定。20名患者(87%)伴有足踝骨折。最常见的骨折部位是小腿骨内侧结节(75%),其次是距骨头(30%)、跗骨窦(25%)和内侧踝骨(25%)。X光片识别骨折的灵敏度为48.1%。平均随访时间为 30 个月。有症状的 OA 患者有 8 名(36.4%)。未发现创伤后距骨血管性坏死。所有创伤后 OA 患者(100%)均出现骨折。五名遭受高能量机制损伤的患者中有三人(66.7%)出现了放射性 OA。在接受切开复位和内固定治疗的六名患者中,有三名(50%)也出现了影像学上的 OA:结论:距骨脱位仍然是一种罕见的损伤。结论:距骨脱位仍是一种罕见的损伤,与足踝骨折密切相关。小腿内侧结节骨折最为常见。创伤后出现有症状的跗骨周围 OA 的风险很高。CT有助于检测隐性骨折和受伤的骨性亚区。我们推测了创伤后 OA 的潜在风险因素(骨折、高能量损伤机制、切开复位和内固定),但这还需要进一步研究。
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引用次数: 0
Tumor diameter and enhancing capsule, as well as previous interventional treatments, as potential predictors of vascular lake phenomenon in hepatocellular carcinoma patients treated with drug-eluting beads transarterial chemoembolization. 药物洗脱珠经动脉化疗栓塞治疗肝细胞癌患者血管湖现象的潜在预测因素--肿瘤直径和增强囊以及先前的介入治疗。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-10 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_66_2024
Kento Hatakeyama, Tomoki Tozawa, Yuki Wada, Motoko Konno, Masazumi Matsuda, Takahiro Otani, Shinichiro Minami, Wataru Sato, Kyoko Nomura, Katsunori Iijima, Naoko Mori

Objectives: The initial drug-eluting bead (DEB)-transarterial chemoembolization (TACE) are often performed after multiple sessions of transarterial infusion chemotherapy (TAI) or conventional TACE. The purpose of our study was to evaluate the factors associated with the occurrence of vascular lake phenomenon (VLP) during DEB-TACE, considering the previous interventional treatments.

Material and methods: Forty-nine initial DEB-TACE procedures in 49 patients between November 2010 and April 2024 were included in this retrospective study. VLP was defined as a localized pooling of contrast agents within the tumor in the venous phase of digital subtraction angiography. The laboratory data, pre-treatment imaging findings such as the maximum tumor diameter (≥3 cm or <3 cm) and the presence of enhancing capsule obtained from computed tomography or magnetic resonance imaging, size of DEBs, and loading drugs, the total number of previous interventional treatments were recorded and compared between VLP occurrence and VLP non-occurrence groups. The multivariate logistic regression analysis was performed to explore the association of factors in predicting VLP occurrence.

Results: VLP was observed in 16 patients (32.65%) out of 49 patients. The maximum tumor diameter (≥3 cm) and the presence of the enhancing capsule were significantly higher, and the total number of previous interventional treatments was significantly smaller in the VLP occurrence group than in the VLP non-occurrence group (P = 0.0006, 0.0007, and 0.0003). In multivariate analysis, the maximum tumor diameter, the presence of the enhancing capsule, and the total number of previous interventional treatments were significantly associated with the occurrence of VLP (P = 0.0048, 0.0093, and 0.047).

Conclusion: Our study confirmed that the reported risk factor, the maximum tumor diameter, and the enhancing capsule were significantly related to the occurrence of VLP in DEB-TACE. Further, the occurrence of VLP might be carefully considered when the number of previous interventional treatments is small.

目的:最初的药物洗脱珠(DEB)-经动脉化疗栓塞(TACE)通常是在多次经动脉灌注化疗(TAI)或传统TACE之后进行的。我们的研究旨在评估在DEB-TACE期间发生血管湖现象(VLP)的相关因素,同时考虑之前的介入治疗:这项回顾性研究纳入了 2010 年 11 月至 2024 年 4 月期间 49 名患者的 49 例初次 DEB-TACE 手术。VLP被定义为数字减影血管造影静脉期造影剂在肿瘤内的局部聚集。实验室数据、治疗前的影像学检查结果,如肿瘤最大直径(≥3 厘米)或结果:49名患者中有16名(32.65%)观察到VLP。发生 VLP 组的肿瘤最大直径(≥3 厘米)和增强囊的存在明显高于未发生 VLP 组(P = 0.0006、0.0007 和 0.0003),既往介入治疗的总次数也明显少于未发生 VLP 组(P = 0.0006、0.0007 和 0.0003)。在多变量分析中,肿瘤最大直径、增强囊的存在以及既往介入治疗的总次数与VLP的发生明显相关(P = 0.0048、0.0093和0.047):我们的研究证实,报告的危险因素、肿瘤最大直径和增强囊与 DEB-TACE VLP 的发生显著相关。此外,当既往介入治疗次数较少时,应慎重考虑 VLP 的发生。
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引用次数: 0
An investigation into the chiropractic practice and communication of routine, repetitive radiographic imaging for the location of postural misalignments. 对脊骨神经科常规、重复放射成像定位姿势错位的实践与交流的调查。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-01 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_68_2024
Brogan Williams, Luke Gichard, David Johnson, Matthew Louis

Many chiropractors use radiological imaging, particularly X-rays, to locate and diagnose the cause of their patients' pain. However, this approach is fundamentally flawed because X-rays provide anatomical information but not functional insights. Pain, tissue damage, and injury do not always correlate directly with X-ray appearances. Given the high incidence of abnormalities found in X-rays of asymptomatic patients, the diagnostic validity of X-rays can be questioned, especially when used in isolation of the patient's history and/or a proper clinical assessment. One may posit that their application promotes overdiagnosis, and unvalidated treatment of X-ray findings (such as changes in postural curvature), which may mislead patients into believing these changes are directly responsible for their pain. A substantial amount of research has shown that there is no association between pain and reversed cervical curves. X-ray accuracy can vary due to several factors, including patient positioning, physical and morphological changes, interreliability among doctors, and other influences such as stress, pain, and emotional state. Over the past two decades, medical boards and health associations worldwide have made significant efforts to communicate better when imaging is necessary, focusing on reducing radiographic imaging. This review describes concerns about the frequent, almost routine use of spinal X-rays in primary care for spine-related pain in the absence of red-flag clinical signs.

许多脊骨神经科医生使用放射成像,尤其是X光,来定位和诊断患者疼痛的原因。然而,这种方法从根本上是有缺陷的,因为X光片只能提供解剖学信息,却不能提供功能方面的见解。疼痛、组织损伤和损伤并不总是与 X 光片的显示直接相关。鉴于在无症状患者的 X 光片中发现异常的发生率很高,X 光片的诊断有效性可能会受到质疑,尤其是在脱离患者病史和/或适当的临床评估的情况下。有人可能会认为,X 射线的应用会助长过度诊断,以及对 X 射线检查结果(如姿势弯曲的变化)进行未经验证的治疗,这可能会误导患者认为这些变化是导致其疼痛的直接原因。大量研究表明,疼痛与颈椎反向弯曲之间没有关联。X 射线的准确性会因多种因素而变化,包括患者的体位、身体和形态变化、医生之间的不可靠因素以及压力、疼痛和情绪状态等其他影响因素。在过去的二十年里,世界各地的医疗委员会和卫生协会已经做出了巨大努力,在有必要进行影像检查时进行更好的沟通,重点是减少放射影像检查。这篇综述介绍了在初级医疗中频繁使用脊柱 X 光片治疗脊柱相关疼痛,几乎是常规做法,但却没有出现值得警惕的临床症状,这种做法令人担忧。
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引用次数: 0
Interruption during drug-eluting beads transarterial chemoembolization procedure by presumed allergic shock requires careful follow-up on the development of vascular lake phenomenon. 在药物洗脱珠经动脉化疗栓塞术过程中,因假定的过敏性休克而中断,需要仔细跟踪血管湖现象的发展。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-31 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_47_2024
Akihiro Ogawa, Yuki Wada, Katsunori Iijima, Naoko Mori

We present a case involving a 60-year-old male with multifocal hepatocellular carcinoma (HCC), emphasizing the critical need for vigilant post-procedural monitoring following the interruption of drug-eluting beads transarterial chemoembolization (DEB-TACE) due to an allergic reaction. The patient, who had a history of various treatments for HCC, underwent DEB-TACE. During the procedure, he experienced an anaphylactic shock, presumably due to an allergy to the treatment components (iodinated contrast agent), resulting in the procedure's discontinuation. Initially stable, the patient was later found to have intra-abdominal bleeding, a complication associated with the vascular lake phenomenon (VLP), detected on post-procedural imaging. Re-embolization using gelatin particles was performed to address the VLP. It remains unclear whether the shock experienced during the DEB-TACE procedure was due to the allergic reaction or the rupture of the VLP. This case underscores the complexities in managing DEB-TACE, the necessity of careful monitoring for VLP, and the challenges in diagnosing and managing allergic reactions during such procedures. In conclusion, it is crucial to consider that VLP can occur at any time during or after DEB-TACE. Assessing the presence of VLP using digital subtraction angiography before the termination of the procedure is essential. However, when an allergy to the iodinated contrast agent is suspected, as in this case, careful follow-up with abdominal ultrasound and computed tomography might be necessary to assess the presence of intra-abdominal hemorrhage associated with VLP.

我们介绍了一例 60 岁男性多灶性肝细胞癌(HCC)患者的病例,强调了因过敏反应而中断药物洗脱珠经动脉化疗栓塞术(DEB-TACE)后进行术后监测的重要性。患者曾接受过多种 HCC 治疗,接受了 DEB-TACE。在手术过程中,他出现了过敏性休克,可能是由于对治疗成分(碘造影剂)过敏,导致手术中止。患者最初病情稳定,但后来发现腹腔内出血,这是一种与血管湖现象(VLP)有关的并发症,在手术后的成像中被发现。为解决 VLP 问题,使用明胶颗粒进行了再次栓塞。目前还不清楚 DEB-TACE 过程中出现的休克是由于过敏反应还是 VLP 破裂所致。该病例突出说明了 DEB-TACE 管理的复杂性、仔细监测 VLP 的必要性以及在此类手术中诊断和管理过敏反应的挑战性。总之,必须考虑到在 DEB-TACE 期间或之后的任何时候都可能出现 VLP。在手术终止前使用数字减影血管造影术评估是否存在 VLP 至关重要。不过,如果怀疑患者对碘化造影剂过敏,就像本病例一样,可能需要通过腹部超声波和计算机断层扫描进行仔细随访,以评估是否存在与 VLP 相关的腹腔内出血。
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引用次数: 0
Does computed tomography-derived volumometry and densitometry of psoas muscle really correlate with complications in rectal cancer patients after elective surgery? 计算机断层扫描得出的腰肌体积测量和密度测量结果真的与直肠癌患者择期手术后的并发症有关吗?
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-24 DOI: 10.25259/jcis_43_2024
Jiri Kotek, Petr Lochman, Michal Hůlek, M. Sirovy, Tomáš Merkl, E. Čermáková, Katerina Kotkova, J. Páral, Tomáš Dušek
Although sarcopenia is recognized as one of the risk factors for increased morbidity after resection for colorectal cancer, the question of the most appropriate way to identify and quantify it is still unresolved.This is a retrospective unicentric study following patients undergoing elective resection of the rectum for carcinoma with available staging computed tomography (CT) of the trunk. Psoas muscle density (PMD) and its area relative to patient height psoas muscle index (PMI) at the level of inferior vertebral end plate of third lumbar vertebra (L3) were assessed using an initial staging CT scan of the trunk. Post-operative complications, evaluated according to the Clavien-Dindo classification, and blood samples on post-operative days (POD) 3 and 5 were also recorded in the study population. Patients were divided into groups with complicated and uncomplicated post-operative course, and observed parameters were then statistically compared.The correlation of PMI values with the development of post-operative complications was not confirmed in a data set of 206 patients. PMD values were found to be borderline statistically significant in patients with complicated post-operative course, while in the group of patients with severe complications (Clavien-Dindo III-IV), there was no statistically significant difference in PMI or PMD values. The same results were obtained when comparing patients with anastomotic leak (AL). It was confirmed that operations on the lower rectum are riskier for the development of post-operative complications. The secondary objective of our study regarding serum C-reactive protein (CRP) levels of 3rd and 5th POD gave us the answer in the form of cutoff values of 115.7 mg/L (3rd POD) and 76 mg/L (5th POD).PMD appears to be a promising tool for predicting post-operative morbidity in patients after rectal resection, but a clear consensus on the method of measurement, interpretation of results and cutoff values is needed. Lower rectal resections are burdened with a higher risk of post-operative complications, especially AL. Monitoring of CRP levels remains an important marker in the prediction of AL due to its negative predictive value.
虽然肌肉疏松症被认为是结肠直肠癌切除术后发病率增加的风险因素之一,但识别和量化肌肉疏松症的最合适方法问题仍未解决。这是一项回顾性单中心研究,研究对象是接受直肠癌择期切除术并进行躯干分期计算机断层扫描(CT)的患者。通过对躯干进行初步分期计算机断层扫描,评估了第三腰椎(L3)下椎体终板水平的腰肌密度(PMD)及其相对于患者身高的腰肌指数(PMI)。根据克拉维恩-丁多分类法评估术后并发症,并记录术后第 3 天和第 5 天的血液样本。患者被分为术后并发症组和术后无并发症组,然后对观察到的参数进行统计比较。在术后病程复杂的患者中,PMD 值在统计学上有边缘意义,而在严重并发症患者组(Clavien-Dindo III-IV)中,PMI 或 PMD 值在统计学上没有显著差异。对吻合口漏(AL)患者进行比较也得出了同样的结果。研究证实,直肠下段手术发生术后并发症的风险较高。我们研究的次要目标是第 3 次和第 5 次 POD 的血清 C 反应蛋白(CRP)水平,并给出了 115.7 毫克/升(第 3 次 POD)和 76 毫克/升(第 5 次 POD)的临界值。PMD 似乎是预测直肠切除术后患者术后发病率的一种有前途的工具,但需要就测量方法、结果解释和临界值达成明确共识。直肠下段切除术术后并发症风险较高,尤其是AL。由于 CRP 具有阴性预测价值,因此监测 CRP 水平仍然是预测 AL 的重要指标。
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引用次数: 0
The efficacy of cone-beam computed tomography-guided transcatheter arterial chemoembolization in hepatocellular carcinoma survival: A systematic review 锥束计算机断层扫描引导下的经导管动脉化疗栓塞术对肝细胞癌生存的疗效:系统性综述
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-17 DOI: 10.25259/jcis_32_2024
Levent Akman Solim, Duygu Atasoy, T. Vogl
Cone-beam computed tomography (CBCT)-guided transcatheter arterial chemoembolization (TACE) represents an alternative treatment option for advanced hepatocellular carcinoma (HCC) patients, yet a comprehensive evaluation of CBCT guidance on this procedure and CBCT’s impact on patient survival remains lacking. We aimed to assess the efficacy and benefits of CBCT-guided TACE in improving survival outcomes for patients with HCC and show the importance of CBCT in interventional radiology. Meta-analysis was conducted to evaluate CBCT-guided TACE compared to conventional TACE in the treatment of HCC. PubMed and Cochrane library databases were searched for studies published. Outcomes of interest included 1- or 3-year local progression-free survival (LPFS) rates, overall survival (OS) rates, and tumor response results. A total of eight studies were included in the meta-analysis, comprising 1176 patients. The analysis showed that CBCT-guided TACE improved 1-year LPFS (odds ratio [OR] = 2.81, P < 0.001), 3-year (OR = 4.42, P = 0.002), and the 3-year OS rates (OR = 3.03, Confidence Interval = 1.65–11.80, P = 0.14) compared to conventional TACE. CBCT-guided TACE enhances survival outcomes for patients with HCC; by addressing this research gap, our study endeavors to encourage clinicians and researchers to pursue this medical technology by providing a robust synthesis of current evidence.
锥形束计算机断层扫描(CBCT)引导下的经导管动脉化疗栓塞术(TACE)是晚期肝细胞癌(HCC)患者的另一种治疗选择,但目前仍缺乏对 CBCT 引导下该手术的全面评估以及 CBCT 对患者生存期的影响。我们旨在评估 CBCT 引导下的 TACE 在改善 HCC 患者生存预后方面的疗效和益处,并展示 CBCT 在介入放射学中的重要性。我们进行了荟萃分析,以评估 CBCT 引导的 TACE 与传统 TACE 在治疗 HCC 方面的比较。我们在 PubMed 和 Cochrane 图书馆数据库中检索了已发表的研究。研究结果包括1年或3年局部无进展生存率(LPFS)、总生存率(OS)和肿瘤反应结果。荟萃分析共纳入了 8 项研究,包括 1176 名患者。分析结果显示,与传统 TACE 相比,CBCT 引导的 TACE 可改善 1 年 LPFS(几率比 [OR] = 2.81,P < 0.001)、3 年(OR = 4.42,P = 0.002)和 3 年 OS 率(OR = 3.03,置信区间 = 1.65-11.80,P = 0.14)。CBCT引导下的TACE提高了HCC患者的生存预后;我们的研究填补了这一研究空白,通过对现有证据进行有力的综合,鼓励临床医生和研究人员追求这一医疗技术。
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引用次数: 0
Clinical characteristics and long-term outcome of patients with bioprosthetic mitral valve- Experience from a South Asian country. 生物人工二尖瓣患者的临床特征和长期疗效--来自南亚国家的经验。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-03 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_39_2024
Aiysha Nasir, Fateh Ali Tipoo Sultan, Rizwan Ali Khawaja, Muhammad Ahmed Tamiz

Objectives: Due to rheumatic heart disease, young people are more likely to develop valvular heart disease in developing countries. In countries like Pakistan, surgeons implant more bioprosthetic mitral valves (MVs) in younger patients. However, bioprosthetic valves degenerate rapidly in younger people, leading to bioprosthetic MV dysfunction (BMVD). This study aims to evaluate the clinical characteristics and long-term outcomes of patients with bioprosthetic MV replacement (MVR) at a tertiary care hospital in a South Asian country.

Material and methods: This is a retrospective observational study, conducted at a tertiary care hospital. We included a total of 502 patients who underwent bioprosthetic MVR from the year 2006 to 2020. Clinical and surgical characteristics along with transthoracic echocardiographic findings (pre-surgery and recent most follow-up studies) were noted. Follow-up data were also collected.

Results: Out of 502 patients, 322 (64%) were female, mean age at the time of surgery was 49.42 ± 14.56 years. Mitral regurgitation was more common, found in 279 (55.6%) patients followed by mitral stenosis in 188 (37.5%) patients. MVR was done as an elective procedure due to the New York Heart Association (NYHA) II to IV symptoms at the time of surgery in 446 (88.8%) patients. In the mean follow-up of 6.59 ± 2.99 years, BMVD was observed in 183 (36.5%) patients. However, re-do MV surgery was done in only 49 (9.8%) patients. Patients were divided into two groups based on normal functioning bioprosthetic MV and BMVD. Comparing the two groups, individuals with normal functioning bioprosthetic MV had a mean age of 51.6 ± 14.27 years, while those with BMVD had a mean age of 45.639 ± 14.33 years at the time of index surgery (P = 0.000). There were more long-term complications including heart failure (n = 16, 8.74%), atrial fibrillation (n = 11, 6.01%), and death (n = 6, 3.28%) in the BMVD group which were statistically significant.

Conclusion: This study is distinct because it demonstrates the outcomes of bioprosthetic valve replacement in a relatively younger South Asian population. Due to rapid degeneration of bioprosthetic valve in younger patients, significant number of patients developed BMVD along with poor long-term clinical outcomes, even at a short follow-up period of <10 years. These findings are similar to international data and signify that mechanical MVR may be a more reasonable alternative in younger patients.

目的:由于风湿性心脏病,发展中国家的年轻人更容易患上瓣膜性心脏病。在巴基斯坦等国家,外科医生为年轻患者植入更多的生物人工二尖瓣(MV)。然而,生物人工瓣膜在年轻人中会迅速退化,导致生物人工二尖瓣功能障碍(BMVD)。本研究旨在评估南亚某国一家三级甲等医院的生物人工瓣膜置换术(MVR)患者的临床特征和长期疗效:这是一项回顾性观察研究,在一家三级医院进行。我们纳入了 2006 年至 2020 年期间接受生物人工心血管置换术的 502 名患者。研究记录了患者的临床和手术特征以及经胸超声心动图检查结果(手术前和最近的随访检查)。同时还收集了随访数据:在 502 名患者中,322 人(64%)为女性,手术时的平均年龄为 49.42 ± 14.56 岁。二尖瓣反流较为常见,有 279 例(55.6%)患者,其次是二尖瓣狭窄,有 188 例(37.5%)患者。446例(88.8%)患者在手术时出现纽约心脏协会(NYHA)II至IV级症状,因此选择进行二尖瓣反流手术。在平均 6.59 ± 2.99 年的随访中,183 例(36.5%)患者观察到 BMVD。然而,只有 49 例(9.8%)患者再次进行了中压手术。根据正常功能的生物假体中压和 BMVD 将患者分为两组。比较两组患者,功能正常的生物假体中压患者的平均年龄为(51.6 ± 14.27)岁,而 BMVD 患者的平均年龄为(45.639 ± 14.33)岁(P = 0.000)。BMVD组有更多的长期并发症,包括心力衰竭(16例,8.74%)、心房颤动(11例,6.01%)和死亡(6例,3.28%),这些并发症在统计学上有显著意义:本研究的独特之处在于它展示了在相对年轻的南亚人群中进行生物人工瓣膜置换术的结果。由于年轻患者的生物人工瓣膜退化迅速,即使在较短的随访期内,也有相当多的患者出现了BMVD,并伴有不良的长期临床预后。
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引用次数: 0
Next-generation digital chest tomosynthesis. 新一代数字胸部断层扫描。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-26 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_4_2024
Christopher Gange, Jamie Ku, Babina Gosangi, Jianqiang Liu, Manat Maolinbay

The objective of this study was to demonstrate the performance characteristics and potential utility of a novel tomosynthesis device as applied to imaging the chest, specifically relating to lung nodules. The imaging characteristics and quality of a novel digital tomosynthesis prototype system was assessed by scanning, a healthy volunteer, and an andromorphic lung phantom with different configurations of simulated pulmonary nodules. The adequacy of nodule detection on the phantoms was rated by chest radiologists using a standardized scale. Results from using this tomosynthesis device demonstrate in plane resolution of 16lp/cm, with estimated effective radiation doses of 90% less than low dose CT. Nodule detection was adequate across various anatomic locations on a phantom. These proof-of-concept tests showed this novel tomosynthesis device can detect lung nodules with low radiation dose to the patient. This technique has potential as an alternative to low dose chest CT for lung nodule screening and tracking.

这项研究的目的是展示一种新型断层合成设备在胸部成像方面的性能特点和潜在用途,特别是与肺结节有关的成像。研究人员通过扫描健康志愿者和带有不同结构模拟肺结节的变形肺部模型,评估了新型数字断层合成原型系统的成像特性和质量。胸部放射科医生使用标准化量表对模型上结节检测的充分性进行评分。使用这种断层合成设备的结果显示,平面分辨率为 16lp/cm,估计有效辐射剂量比低剂量 CT 低 90%。在模型上的不同解剖位置,结节检测都很充分。这些概念验证测试表明,这种新型断层合成设备能以较低的辐射剂量检测到肺部结节。这项技术有望替代低剂量胸部 CT,用于肺结节筛查和追踪。
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引用次数: 0
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Journal of Clinical Imaging Science
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