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Complete contrast staining of hepatocellular carcinoma during drug-eluting bead chemoembolization predicts a favorable response. 肝细胞癌在药物洗脱珠化疗栓塞期间的完全对比染色预测良好的反应。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-11-27 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_129_2024
Sultan R Alharbi

Objective: The objective of this study was to evaluate complete contrast staining (CCS) of HCC during drug-eluting bead transarterial chemoembolization (DEBTACE) first session for response prediction.

Methods: Forty-one patients with solitary HCC who underwent DEBTACE were retrospectively enrolled and divided into two groups based on contrast staining of HCC using two-dimensional (2D) fluoroscopy during the first session of DEBTACE. Both groups underwent one or two sessions of DEBTACE to achieve a complete response. Responses were evaluated using the modified Response Evaluation Criteria in Solid Tumors. A comparison of the complete response between the CCS and non-CCS groups was performed, and the prediction value was studied.

Results: CCS in 2D fluoroscopy during the first session of drug-eluting bead chemoembolization was observed in 22 (53.7%) patients. Well-defined HCC and super-selective chemoembolization were significantly associated with CCS. Complete response was observed in 54.54%, 90%, and 95.45% of CCS patient groups after the first session, second session, and cumulative sessions of TACE, respectively. Complete responses were 10.52%, 29.41%, and 36.84% in the non-CCS group after the first, second, and cumulative sessions of TACE, respectively.

Conclusion: CCS of HCC using 2D fluoroscopy during DEBTACE is a predictor of a favorable response after two sessions of treatment.

目的:本研究的目的是评估HCC在药物洗脱经动脉化疗栓塞(DEBTACE)第一次疗程中的完全对比染色(CCS)以预测反应。方法:回顾性纳入41例行DEBTACE的孤立性HCC患者,并根据DEBTACE第一次期间使用二维(2D)透视对HCC的对比染色分为两组。两组患者均接受一到两次DEBTACE治疗以达到完全缓解。使用修改后的实体瘤反应评价标准对反应进行评价。比较CCS组和非CCS组的完全反应,并研究其预测值。结果:22例(53.7%)患者在第一次药物洗脱珠状化疗栓塞期间的二维透视中观察到CCS。明确的HCC和超选择性化疗栓塞与CCS显著相关。在第一次TACE治疗、第二次TACE治疗和累计TACE治疗后,54.54%、90%和95.45%的CCS患者组出现完全缓解。在第一次、第二次和累计TACE治疗后,非ccs组的完全缓解率分别为10.52%、29.41%和36.84%。结论:在DEBTACE期间使用二维透视检查HCC的CCS是两个疗程治疗后良好反应的预测指标。
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引用次数: 0
Frequency of myocardial infarcts on conventional, non-gated CT: An often-overlooked entity. 常规非门控CT上心肌梗死的频率:一个经常被忽视的实体。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-11-21 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_114_2024
Jabi Elijah Shriki, Ashley Elizabeth Prosper, Jerold Shinbane, Patrick M Colletti

Objectives: The objective of this study was to determine how often myocardial infarctions are retrospectively visible on conventional, non-gated, non-cardiac computed tomography (CT) scans. Our goal was to evaluate a cohort of patients with myocardial infarctions visible on cardiac magnetic resonance imaging (MRI) to determine how often the area of infarction was retrospectively visible by preceding, conventional CT. We also sought to evaluate how often the diagnosis of myocardial infarction was reported at the time of initial study review.

Material and methods: The Institutional Review Board approval was obtained for the creation and retrospective analysis of a database of patients undergoing cardiac MRI. We started with a cohort of 252 patients who had undergone cardiac MRI at our institution, over a 4-year period. We identified 160 patients who had a myocardial infarct visible on MRI.

Results: Of the 160 patients who had been identified as having an infarct on cardiac MRI, 54 patients had undergone a recent (within 30 days) conventional CT scan, usually done for non-cardiac indications. In addition to the review of reports, non-cardiac CT scans were also evaluated retrospectively by two experienced, cardiothoracic imaging physicians, including a radiologist and a cardiologist. In 26 of these patients (48.1%), an infarct was visible on the CT images. In 12 of these 26 cases (46.1%), the infarct was noted in the initial report. In the remaining 14 of these 26 cases (53.8%), the infarct was unrecognized at the time of initial study interpretation.

Conclusion: Our retrospective analysis demonstrates that myocardial infarctions may be frequently observed on non-gated, non-cardiac CT scans but may be underrecognized and under-reported.

目的:本研究的目的是确定在常规、非门控、非心脏计算机断层扫描(CT)上回顾性观察心肌梗死的频率。我们的目的是评估一组在心脏磁共振成像(MRI)上可见心肌梗死的患者,以确定通过之前的常规CT回顾性显示梗死区域的频率。我们还试图评估在最初研究回顾时报告心肌梗死诊断的频率。材料和方法:获得了机构审查委员会的批准,用于创建和回顾性分析接受心脏MRI的患者数据库。我们从一组252名患者开始,他们在我们的机构接受了心脏MRI,为期4年。我们确定了160例MRI可见心肌梗死的患者。结果:在160例心脏MRI诊断为梗死的患者中,54例患者最近(30天内)进行了常规CT扫描,通常用于非心脏适应症。除了回顾报告外,两位经验丰富的心胸影像学医生(包括放射科医生和心脏病科医生)也对非心脏CT扫描进行了回顾性评估。其中26例(48.1%)在CT图像上可见梗死灶。在这26例病例中,有12例(46.1%)在最初的报告中发现了梗死。其余14例(53.8%)在最初的研究解释时未发现梗死。结论:我们的回顾性分析表明,心肌梗死可能经常在非门控、非心脏CT扫描上被观察到,但可能被低估和报道不足。
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引用次数: 0
Volumetric analysis of maxillary sinus and assessment of various sinonasal anatomic variants on multi-detector computed tomography (MDCT) and their association with chronic rhinosinusitis. 上颌窦的体积分析和多探测器计算机断层扫描(MDCT)对各种鼻窦解剖变异的评估及其与慢性鼻窦炎的关系。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-11-18 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_124_2024
Aman Taneja, Ankur Malhotra, Shruti Chandak, Swasti Jain, Arpit Taneja, Deepti Arora, Swarna Laxmi, Aishwarya Pandey

Objectives: The study aimed to evaluate the relationship between maxillary sinus volume and various sinonasal anatomical variants, as detected by multi-detector computed tomography, and their associations with chronic rhinosinusitis (CRS).

Material and methods: A case-control study was conducted with 103 patients presenting with chronic sinonasal symptoms (cases) and 50 asymptomatic individuals (controls). A 128-slice computed tomography scanner was used to measure maxillary sinus volume and assess anatomical variants, such as a deviated nasal septum (DNS), concha bullosa (CB), and agger nasi cells. Exclusion criteria included previous sinonasal surgery, malignancy, craniofacial trauma, and lack of consent. Statistical analysis was performed using t-tests for continuous variables and Chi-square tests for categorical data. Receiver operating characteristic curve analysis was utilized to determine a DNS angle cutoff for predicting CRS.

Results: Anatomical variants were significantly more frequent in cases than in controls. The left-sided DNS was predominant in cases, while the right-sided DNS was more common in controls. The mean DNS deviation angle was notably larger in cases (10.84° ± 7.87) than in controls (5.55° ± 5.02). Maxillary sinus volume was significantly smaller in cases (9.69 cc on the left side and 10.23 cc on the right side) compared to controls (18.57 cc and 18.46 cc, respectively), with female patients exhibiting smaller volumes than males. Agger nasi cells were detected in 51.5% of cases versus 8.0% of controls. A strong association was found between CB and contralateral DNS. The optimal DNS deviation angle cutoff for predicting CRS was identified as 12.7°.

Conclusion: This study shows that CRS is linked to smaller maxillary sinus volumes, with males having larger sinus volumes than females. A DNS and larger deviation angles were associated with a higher risk of sinus inflammation, with angles over 12.7° predicting the onset of the condition. The presence of CB and agger nasi cells also contributed to the development of CRS.

目的:本研究旨在评估上颌窦体积与多探测器计算机断层扫描检测到的各种鼻窦解剖变异之间的关系,以及它们与慢性鼻窦炎(CRS)的关系。材料与方法:对103例慢性鼻窦症状患者(病例)和50例无症状患者(对照组)进行病例对照研究。使用128层计算机断层扫描仪测量上颌窦体积并评估解剖变异,如鼻中隔偏曲(DNS)、甲壳大疱(CB)和鼻窦细胞聚集。排除标准包括既往鼻窦手术、恶性肿瘤、颅面创伤和缺乏同意。对连续变量采用t检验,对分类数据采用卡方检验进行统计分析。利用接收机工作特性曲线分析确定预测CRS的DNS角度截止点。结果:病例中解剖变异明显高于对照组。左侧DNS在病例中占主导地位,而右侧DNS在对照组中更常见。患者的平均DNS偏差角(10.84°±7.87)明显大于对照组(5.55°±5.02)。与对照组(分别为18.57 cc和18.46 cc)相比,上颌窦体积明显较小(左侧为9.69 cc,右侧为10.23 cc),女性患者的体积小于男性。51.5%的病例检测到鼻艾格细胞,而对照组为8.0%。在CB和对侧DNS之间发现了强烈的关联。预测CRS的最佳DNS偏差角截止值为12.7°。结论:本研究表明CRS与上颌窦体积较小有关,男性上颌窦体积大于女性。一个DNS和较大的偏离角度与窦炎的高风险相关,角度超过12.7°预示着病情的发作。CB细胞和鼻窦聚集细胞的存在也促进了CRS的发生。
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引用次数: 0
Transarterial embolization of intralobar pulmonary sequestration in adult patients: A case series. 经动脉栓塞治疗成人肺叶内肺隔离:一个病例系列。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-11-04 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_108_2024
Andrea Benson, Yaron Perry, Andrew Cantos, Devang Butani, Harris Chengazi

Pulmonary sequestration is a malformation of lung tissue such that a zone of pulmonary parenchyma exists in isolation from the bronchopulmonary tree. This condition is typically treated with surgical resection, but an increasing number of sequestrations are being treated with arterial embolization. We report interventions that were performed at two institutions on patients 53-70 years old. One patient presented with chronic cough and the two other patients presented with hemoptysis. Two of the cases were managed solely by endovascular embolization of the arteries supplying the pulmonary sequestration. In one patient, embolization was performed to debulk the sequestration, followed by surgical resection. These cases suggest transcatheter embolization may be an effective treatment in adult patients with symptomatic pulmonary sequestrations.

肺隔离是肺组织的一种畸形,使肺实质区与支气管肺树分离存在。这种情况通常用手术切除治疗,但越来越多的隔离正在用动脉栓塞治疗。我们报告了在两家机构对53-70岁患者进行的干预。1例患者表现为慢性咳嗽,另外2例患者表现为咯血。其中2例仅通过血管内栓塞治疗肺动脉隔离。在一名患者中,进行了栓塞以清除隔离,随后进行了手术切除。这些病例提示经导管栓塞可能是治疗有症状性肺隔离的成人患者的有效方法。
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引用次数: 0
Three main portal veins: A very rare case of portal vein anomaly. 三条主要门静脉一个非常罕见的门静脉异常病例。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_107_2024
Guilong Liu, Linfeng Song, Youquan Li, Lin Jiang

Portal vein (PV) anomalies are rare during embryonic development, with very few cases of duplicated PVs reported. This case reveals a new PV trunk anomaly, where computed tomography venography imaging shows three portal veins. The superior mesenteric vein and inferior mesenteric vein join to form a trunk that divides into two branches: One entering the liver (PV1) and the other ascending to join the splenic vein. The splenic vein then divides into two branches in the neck of the pancreas (PV2 and PV3), both entering the liver. The three PVs vary in thickness and all enter the liver through the first hepatic portal. Understanding the normal structure and anatomy of the PV is important for successful surgical planning. This case involves three main trunks of the PV, which is an extremely rare type of PV duplication anomaly. Reporting this case aims to enhance the awareness and understanding of PV duplication anomalies among clinicians and radiologists.

门静脉(PV)异常在胚胎发育过程中非常罕见,很少有门静脉重复的报道。本病例显示了一种新的门静脉主干异常,计算机断层扫描静脉成像显示有三条门静脉。肠系膜上静脉和肠系膜下静脉汇合形成一条主干,主干分为两条分支:一条进入肝脏(PV1),另一条上升汇入脾静脉。然后,脾静脉在胰腺颈部分为两支(PV2 和 PV3),均进入肝脏。三条肝静脉粗细不同,都通过第一肝门进入肝脏。了解 PV 的正常结构和解剖对于成功制定手术计划非常重要。本病例涉及三条主干的肝静脉,是极其罕见的肝静脉重复异常类型。报告此病例的目的是提高临床医生和放射科医生对外周静脉重复畸形的认识和理解。
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引用次数: 0
Granulomatous prostatitis following Bacillus Calmette-Guérin therapy. 卡介苗治疗后的肉芽肿性前列腺炎
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-17 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_47_2023
Siddhi Hegde, Dhairya A Lakhani, Ion Prisneac, Brian Markovich

Granulomatous prostatitis (GP) is a rare form of chronic prostatitis with reported incidence of 0.65-1.5%. Radiological features of GP overlap with those of prostate adenocarcinoma. The following magnetic resonance imaging characteristics can suggest the diagnosis in an appropriate clinical setting: Diffuse or focal nodular low T2 signal, high signal on diffusion-weighted imaging with corresponding low apparent diffusion coefficient signal, and post-contrast imaging with lesion enhancement or rim-enhancing in the setting of caseous necrosis or abscess formation. Even with suspicion on imaging, the overlapping imaging features with prostate adenocarcinoma necessitate biopsy for confirmatory diagnosis. Here, we report a case of a 70-year-old man with GP in the setting of prior intravesicle bacillus Calmette-Guérin administration.

肉芽肿性前列腺炎(GP)是一种罕见的慢性前列腺炎,据报道发病率为 0.65%-1.5%。肉芽肿性前列腺炎的放射学特征与前列腺腺癌重叠。在适当的临床环境下,以下磁共振成像特征可提示诊断:弥漫性或局灶性结节性低 T2 信号,弥散加权成像高信号并伴有相应的低表观弥散系数信号,对比成像后病灶增强或在病理坏死或脓肿形成时边缘增强。即使在影像学上有所怀疑,但由于影像学特征与前列腺腺癌重叠,仍有必要进行活检以确诊。在此,我们报告了一例 70 岁男性 GP 患者的病例,患者曾在膀胱内注射卡介苗。
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引用次数: 0
Granulomatous mastitis following stereotactic core-needle biopsy: A case report. 立体定向核心针活检后的肉芽肿性乳腺炎:病例报告。
IF 16.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-10 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_53_2024
Laura L Kirk, Robert J McDonald, Aurela X Clark

Idiopathic granulomatous mastitis is a rare, chronic inflammatory disease of the breast of uncertain etiology that can mimic breast cancer. In rare instances, it may emerge secondary to trauma to the breast. We present a case of a 66-year-old woman who initially underwent a benign stereotactic core-needle biopsy of her left breast complicated by a small hematoma which initially remained unchanged mammographically and sonographically for 1 year; then, it enlarged unexpectedly at the 21-month interval follow-up prompting an ultrasound-guided biopsy revealing granulomatous mastitis.

特发性肉芽肿性乳腺炎是一种罕见的慢性乳腺炎症性疾病,病因不明,可与乳腺癌相似。在极少数情况下,它可能继发于乳房创伤。我们介绍了一例 66 岁女性的病例,她最初接受了左侧乳房的良性立体定向核芯针活检术,术后并发了一个小血肿,该血肿在 1 年内的乳腺和声像图上均无变化,但在 21 个月的随访期间,血肿意外增大,促使她接受了超声引导下的活检术,结果显示为肉芽肿性乳腺炎。
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引用次数: 0
Multimodal imaging findings of tubulocystic renal cell carcinoma: A case report. 肾小管囊肿性肾细胞癌的多模态成像发现:病例报告。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_93_2024
Song Chen, Jiaqi Zhao, Jun Xin, Xiaohuan Yang

We present a case involving a 71-year-old male with tubulocystic renal cell carcinoma (TRCC), which is a rare entity of renal neoplasm. The patient was admitted for a cystic nodule on the middle pole of the right kidney by urological ultrasound during physical examination. The nodule presented with hyperechoic on conventional ultrasonic and the enhancing intensity of thicken cystic wall at the peak phase in contrast-enhanced ultrasound was similar to that of the renal parenchyma. Findings from computed tomography angiography exhibited heterogeneously contrast enhancing tumor, and magnetic resonance imaging demonstrated hypointense on T1-weighted images (WI) and hyperintense on T2WI. Histologically, the spongy surface was composed of the typical tubular and multiloculated cystic components lined by a single layer of epithelial cells. The final pathological diagnosis was TRCC. The uneventful laparoscopic right radical nephrectomy was conducted. The patient was followed up for 12 months after discharge and no signs of local or distant metastasis were found. In conclusion, TRCC should be accurately diagnosed on the basis of comprehensive radiological and histological findings to ensure a timely surgery and better prognosis.

我们报告了一例 71 岁男性肾小管囊性细胞癌(TRCC)患者的病例,这是一种罕见的肾肿瘤。患者因体检时发现右肾中极有一个囊性结节,经泌尿科超声检查后入院。该结节在常规超声检查中呈高回声,在对比增强超声检查中,增厚的囊壁在峰值相的增强强度与肾实质相似。计算机断层扫描血管造影显示肿瘤呈异质性对比增强,磁共振成像显示 T1 加权成像(WI)呈低密度,T2WI 呈高密度。组织学上,海绵表面由典型的管状和多房囊性成分组成,内衬单层上皮细胞。最终病理诊断为 TRCC。患者顺利地接受了腹腔镜右肾根治术。患者出院后随访 12 个月,未发现局部或远处转移迹象。总之,TRCC 应根据放射学和组织学的综合结果进行准确诊断,以确保及时手术和更好的预后。
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引用次数: 0
Computed tomography and magnetic resonance imaging findings of intracranial and extracranial meningioma with perineural spread through the foramen rotundum: A case report. 计算机断层扫描和磁共振成像发现颅内和颅外脑膜瘤通过圆孔进行神经周围扩散:病例报告。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_97_2024
Taketo Suto, Hiroki Kato, Takenori Ogawa, Masayuki Matsuo

We report a case of a 73-year-old woman presenting with intracranial and extracranial meningioma with perineural spread crossing the foramen rotundum and pterygopalatine fossa, primarily along the maxillary nerve. She visited our hospital with the chief complaint of the left cheek swelling. Subsequent magnetic resonance imaging revealed a well-demarcated mass containing intracranial (cavernous sinus, Meckel's cave, and middle cranial fossa) and extracranial components (pterygopalatine fossa, orbit, nasal cavity, ethmoid and sphenoid sinuses, infratemporal fossa, and buccal space) through the foramen rotundum. A biopsy specimen was obtained from the cheek mass, and the histopathological diagnosis was meningothelial meningioma.

我们报告了一例 73 岁女性患者的病例,她患有颅内和颅外脑膜瘤,瘤周硬膜外蔓延,穿过圆形孔和翼腭窝,主要沿上颌神经蔓延。她以左脸颊肿胀为主诉来我院就诊。随后的磁共振成像显示,该肿块分界清晰,包含颅内(海绵窦、梅克尔洞和中颅窝)和颅外(翼腭窝、眼眶、鼻腔、乙状窦和鼻窦、颞下窝和颊间隙)穿过圆孔的部分。从脸颊肿块中获取了活检标本,组织病理学诊断为脑膜上皮脑膜瘤。
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引用次数: 0
Roadmap to success: Blueprint for enterprise-wide deployment of a point-of-care ultrasound platform, inclusive of governance, policy, education, credentialing, and quality assurance. 成功路线图:在全企业范围内部署护理点超声平台的蓝图,包括管理、政策、教育、资格认证和质量保证。
IF 1.1 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-16 eCollection Date: 2024-01-01 DOI: 10.25259/JCIS_96_2024
David Waldman, Chelsea Pino

Point-of-care ultrasound (POCUS) has emerged as a cost-effective diagnostic tool that significantly augments physical examinations. Positioned as an extension of traditional examination methods, particularly appealing to the upcoming generation of clinicians, it holds promise in potentially replacing the stethoscope in various medical assessments and procedures. The University of Rochester is deploying 2500 POCUS machines, enhancing compliance for image storage and documentation. Halfway through our 4-year deployment plan, we will discuss our governance structure, educational initiatives, and credentialing strategies. While POCUS adoption has seen organic growth over the past decade, our aim is to implement a comprehensive strategy ensuring adherence to established protocols for image storage and documentation. At present, we have successfully deployed 789 probes, with integration across 64 departments or divisions into our IT platform. Notably, this implementation has resulted in a remarkable 116% increase in hospital charges, underscoring the tangible impact of POCUS integration. However, achieving compliance and education among established providers has proven to be challenging.

护理点超声波(POCUS)已成为一种具有成本效益的诊断工具,可大大增强体格检查的效果。它被定位为传统检查方法的延伸,特别吸引新一代临床医生,有望在各种医疗评估和程序中取代听诊器。罗切斯特大学正在部署 2500 台 POCUS 机器,以提高图像存储和记录的合规性。我们的四年部署计划已经过半,我们将讨论我们的管理结构、教育计划和认证策略。在过去的十年中,POCUS 的应用实现了有机增长,而我们的目标是实施一项全面的战略,确保遵守既定的图像存储和文档记录协议。目前,我们已成功部署了 789 个探头,并将 64 个部门或分部整合到我们的 IT 平台中。值得注意的是,这一举措使医院的收费显著增加了 116%,凸显了 POCUS 集成的实际效果。然而,事实证明,在现有医疗机构中实现合规性和教育是一项挑战。
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引用次数: 0
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Journal of Clinical Imaging Science
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