Pub Date : 2016-01-01DOI: 10.18488/JOURNAL.98/2016.3.1/98.1.21.26
Fatemeh Sayahi, S. Jalaie
This review employed to establish frequency usage of clinical markers and diagnostic tests for childhood apraxia of speech. following databases were searched for published papers between 1980 and 2015 looking for clinical studies used the six introduced tests for motor speech performance; Web of Science, Scopus, CINAHL and Pubmed. . The review considered articles which for children at or below elementary school age with diagnosis of childhood apraxia of speech. Fifty seven articles met the inclusion criteria. Studies included other developmental motor speech disorders as well as childhood apraxia of speech were excluded. Twenty four articles excluded from the study and thirty three studies were reviewed. Twenty articles were in diagnostic tests and thirteen articles were in clinical markers. The Verbal Motor Production Assessment for Children is the most reliable diagnostic test for diagnosis of childhood apraxia of speech, and Inconsistency as well as vowel errors are the most frequent clinical markers.
本综述旨在建立儿童言语失用症的临床标志物和诊断测试的使用频率。在以下数据库中检索了1980年至2015年间发表的论文，寻找使用六种引入的运动语言表现测试的临床研究;Web of Science, Scopus, CINAHL和Pubmed. .本综述考虑了诊断为儿童言语失用症的小学年龄或以下儿童的文章。57篇文章符合纳入标准。研究包括其他发展性运动语言障碍以及儿童语言失用症被排除在外。本研究排除的24篇文章和33篇研究进行了综述。诊断试验20篇，临床标记物13篇。儿童言语运动产生评估是诊断儿童言语失用症最可靠的诊断测试，不一致和元音错误是最常见的临床标志。
{"title":"Diagnosis of Childhood Apraxia of Speech: A Systematic Review","authors":"Fatemeh Sayahi, S. Jalaie","doi":"10.18488/JOURNAL.98/2016.3.1/98.1.21.26","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2016.3.1/98.1.21.26","url":null,"abstract":"This review employed to establish frequency usage of clinical markers and diagnostic tests for childhood apraxia of speech. following databases were searched for published papers between 1980 and 2015 looking for clinical studies used the six introduced tests for motor speech performance; Web of Science, Scopus, CINAHL and Pubmed. . The review considered articles which for children at or below elementary school age with diagnosis of childhood apraxia of speech. Fifty seven articles met the inclusion criteria. Studies included other developmental motor speech disorders as well as childhood apraxia of speech were excluded. Twenty four articles excluded from the study and thirty three studies were reviewed. Twenty articles were in diagnostic tests and thirteen articles were in clinical markers. The Verbal Motor Production Assessment for Children is the most reliable diagnostic test for diagnosis of childhood apraxia of speech, and Inconsistency as well as vowel errors are the most frequent clinical markers.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"45 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81356794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.18488/JOURNAL.98/2015.2.2/98.2.10.17
Martis Manohar H M, P. Shetty, Hegde B R
Objective: Necrotizing fasciitis is a surgical emergency often requiring prompt diagnosis and treatment. Delay in surgical intervention can have catastrophic results including death. The laboratory risk indicator for necrotizing fasciitis (LRINEC) score uses laboratory parameters to assess the severity of infection and helps in early recognition of necrotizing fasciitis. i?½In this study, we collected the data of 40 patients diagnosed and treated as necrotizing fasciitis to validate the reliability of this score in early diagnosis of necrotizing fasciitis. Materials and methods: This is a retrospective study. Data of 40 patients admitted to Fr. Muller Medical College Hospital, Mangalore from August, 2012 to August, 2014 with a clinical diagnosis of Necrotizing fasciitis was analyzed and relevant statistical tests were applied to evaluate the reliability of the LRINEC score. Results: A total of 40 patients were included in the study. A LRINEC score of > 6 had a sensitivity of i?½ 93.10 %, specificity of 90.91%, positive predictive value of 96.43%, and negative predictive value of 83.33%. The most common organism isolated on culture was Staphylococcus aureus. Conclusion: The LRINEC score is an impressive diagnostic tool to differentiate between necrotizing fasciitis and other less severe soft tissue infections. It aids in early recognition of necrotizing fasciitis enabling prompt and appropriate treatment.
{"title":"Reliability of the Laboratory Risk Indicator for Necrotizing Fasciitis (Lrinec) Score for Early Diagnosis of Necrotizing Fasciitis","authors":"Martis Manohar H M, P. Shetty, Hegde B R","doi":"10.18488/JOURNAL.98/2015.2.2/98.2.10.17","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2015.2.2/98.2.10.17","url":null,"abstract":"Objective: Necrotizing fasciitis is a surgical emergency often requiring prompt diagnosis and treatment. Delay in surgical intervention can have catastrophic results including death. The laboratory risk indicator for necrotizing fasciitis (LRINEC) score uses laboratory parameters to assess the severity of infection and helps in early recognition of necrotizing fasciitis. i?½In this study, we collected the data of 40 patients diagnosed and treated as necrotizing fasciitis to validate the reliability of this score in early diagnosis of necrotizing fasciitis. Materials and methods: This is a retrospective study. Data of 40 patients admitted to Fr. Muller Medical College Hospital, Mangalore from August, 2012 to August, 2014 with a clinical diagnosis of Necrotizing fasciitis was analyzed and relevant statistical tests were applied to evaluate the reliability of the LRINEC score. Results: A total of 40 patients were included in the study. A LRINEC score of > 6 had a sensitivity of i?½ 93.10 %, specificity of 90.91%, positive predictive value of 96.43%, and negative predictive value of 83.33%. The most common organism isolated on culture was Staphylococcus aureus. Conclusion: The LRINEC score is an impressive diagnostic tool to differentiate between necrotizing fasciitis and other less severe soft tissue infections. It aids in early recognition of necrotizing fasciitis enabling prompt and appropriate treatment.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"14 1","pages":"10-17"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72887636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.18488/JOURNAL.98/2015.2.1/98.1.5.9
Y. Soyoral, B. Özbay, H. Begenik, M. Aldemir, R. Erkoç, Deniz Bulut
Retroperitoneal fibrosis (RPF) is a rare disorder manifested by fibrosis and chronic inflammation in the retroperitoneal tissue. It has been reported that retroperitoneal fibrosis is induced by tuberculosis infection (4). We wanted to present a case of latent tuberculosis, who presented with anuria and developed by bilateral hydronephrosis depending on idiopathic RPF, and treated with steroid therapy, since it is a rare case.
{"title":"The Successful Treatment of Obstructive Uropathy Caused By Retroperitoneal Fibrosis with Steroids in the Latent Tuberculosis Case","authors":"Y. Soyoral, B. Özbay, H. Begenik, M. Aldemir, R. Erkoç, Deniz Bulut","doi":"10.18488/JOURNAL.98/2015.2.1/98.1.5.9","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2015.2.1/98.1.5.9","url":null,"abstract":"Retroperitoneal fibrosis (RPF) is a rare disorder manifested by fibrosis and chronic inflammation in the retroperitoneal tissue. It has been reported that retroperitoneal fibrosis is induced by tuberculosis infection (4). We wanted to present a case of latent tuberculosis, who presented with anuria and developed by bilateral hydronephrosis depending on idiopathic RPF, and treated with steroid therapy, since it is a rare case.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"65 1","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73392303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.18488/JOURNAL.98/2015.2.1/98.1.1.4
Kaushik Ghosh, S. Sikdar, Susmita Ghosh, Ambarish Bhattacharyya, Sisir Chakraborty, A. Bag
Finding a reversible cause of pulmonary oedema due to left ventricular dysfunction in intensive care unit is very rare.Here we describe such an event in a young lady who has been diagnosed subsequently as Systemic Lupus Erythromatosus with cardiomyopathy and treated successfully. From ‘Do Not Resuscitate, to ‘doing well’ this is really an encouraging success story.
{"title":"Heart Failure in a Young Lady: A Reversible Cause","authors":"Kaushik Ghosh, S. Sikdar, Susmita Ghosh, Ambarish Bhattacharyya, Sisir Chakraborty, A. Bag","doi":"10.18488/JOURNAL.98/2015.2.1/98.1.1.4","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2015.2.1/98.1.1.4","url":null,"abstract":"Finding a reversible cause of pulmonary oedema due to left ventricular dysfunction in intensive care unit is very rare.Here we describe such an event in a young lady who has been diagnosed subsequently as Systemic Lupus Erythromatosus with cardiomyopathy and treated successfully. From ‘Do Not Resuscitate, to ‘doing well’ this is really an encouraging success story.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"16 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78131468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.18488/journal.98/2016.3.1/98.1.1.10
Mohamad Alwan, S. Sadek
The abnormalities of the kidney can be identified by ultrasound imaging. The kidney may have structural abnormalities like kidney swelling, or change in its position and appearance. Kidney abnormality may also arise due to the formation of stones, congenital anomalies, blockage of urine etc. For surgical operations it is very important to identify the exact and accurate location of stone in the kidney. The ultrasound images are of low contrast and contain speckle noise and could affect human body in some situations like pregnancy. This makes the detection of kidney abnormalities rather challenging task. Thus, microwave imaging could be a good alternative. A microstrip patch antenna scanning system allows to identify the exact and accurate location of stone in the kidney. A physical testing system will be developed in order to generate antenna response surfaces on material which could represent the human body. The serum is used in the experimental measurement because it has similar dielectric properties as human body. In order to represent stone presence in an homogenous medium, small calcium sto ne bearings of different sizes embedded are used to simulate the abnormality. Compact microstrip patch antenna were designed and tested at different frequencies in ISM band : 2.26 GHz, 2.38 GHz, 2.5 GHz, and 2.62 GHz for the RF investigation imaging system in order to detect and localize stones in the kidney.
{"title":"Investigation of Kidney Stone Using a Microstrip Patch Antenna Scanning System","authors":"Mohamad Alwan, S. Sadek","doi":"10.18488/journal.98/2016.3.1/98.1.1.10","DOIUrl":"https://doi.org/10.18488/journal.98/2016.3.1/98.1.1.10","url":null,"abstract":"The abnormalities of the kidney can be identified by ultrasound imaging. The kidney may have structural abnormalities like kidney swelling, or change in its position and appearance. Kidney abnormality may also arise due to the formation of stones, congenital anomalies, blockage of urine etc. For surgical operations it is very important to identify the exact and accurate location of stone in the kidney. The ultrasound images are of low contrast and contain speckle noise and could affect human body in some situations like pregnancy. This makes the detection of kidney abnormalities rather challenging task. Thus, microwave imaging could be a good alternative. A microstrip patch antenna scanning system allows to identify the exact and accurate location of stone in the kidney. A physical testing system will be developed in order to generate antenna response surfaces on material which could represent the human body. The serum is used in the experimental measurement because it has similar dielectric properties as human body. In order to represent stone presence in an homogenous medium, small calcium sto ne bearings of different sizes embedded are used to simulate the abnormality. Compact microstrip patch antenna were designed and tested at different frequencies in ISM band : 2.26 GHz, 2.38 GHz, 2.5 GHz, and 2.62 GHz for the RF investigation imaging system in order to detect and localize stones in the kidney.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"47 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73807168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.18488/JOURNAL.98/2015.2.2/98.2.18.23
M. Younus, Aiysha Ejaz, Mu Khan, A. Maqbool, Q. Nisa, Sanan Raza, A. Khan
Dengue fever is a fatal infection affecting the lives of the patients and this study was designed to further explore its pathological effects. A total of 200 consecutives of dengue viral infection were included in this prospective descriptive study conducted at the Department of Pathology, University of Veterinary and Animal Sciences, Lahore from October, 2009 to September, 2010. A special proforma was designed to collect all the relevant clinical information from each patient. All the strip positive cases of dengue virus were further confirmed by performing IgM capture ELISA and then analyzed for hepatic impairment through liver function tests including serum bilirubin, serum alkaline phosphatase, serum ALT and AST. The results were then gathered and analyzed. The already existing liver diseases like hepatitis A, B, C, E and inherited liver disorders were not included in the study. Total number of patients included in study with Dengue IgM +ve were 200. Out of 200 cases 130 were male and 70 were females. The patients were categorized into two classes according to severity of sign symptoms like puerperal rash on the body. The classes are dengue fever (DF) and dengue hemorrhagic fever (DHF). The total number of DF cases was 28.50% (57/200) and number of DHF cases was 71.50% (143/200). The patients of DHF group were found to have more liver derangement that is 90.20% (128/200) while the patients belonging to DF group were at a less risk for impairment of liver function that is 9.80% (15/200). The patients with dengue hemorrhagic fever are more prone to have liver enzyme derangement and it has a direct relation with the titer IgM in the body of patients infected with dengue virus. The liver enzyme which are found to be more raised are serum ALT and AST while serum alkaline phosphatase and serum bilirubin are not markedly raised.
{"title":"Study of Hepatic Dysfunction in Patientsinfected with Dengue Virus","authors":"M. Younus, Aiysha Ejaz, Mu Khan, A. Maqbool, Q. Nisa, Sanan Raza, A. Khan","doi":"10.18488/JOURNAL.98/2015.2.2/98.2.18.23","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2015.2.2/98.2.18.23","url":null,"abstract":"Dengue fever is a fatal infection affecting the lives of the patients and this study was designed to further explore its pathological effects. A total of 200 consecutives of dengue viral infection were included in this prospective descriptive study conducted at the Department of Pathology, University of Veterinary and Animal Sciences, Lahore from October, 2009 to September, 2010. A special proforma was designed to collect all the relevant clinical information from each patient. All the strip positive cases of dengue virus were further confirmed by performing IgM capture ELISA and then analyzed for hepatic impairment through liver function tests including serum bilirubin, serum alkaline phosphatase, serum ALT and AST. The results were then gathered and analyzed. The already existing liver diseases like hepatitis A, B, C, E and inherited liver disorders were not included in the study. Total number of patients included in study with Dengue IgM +ve were 200. Out of 200 cases 130 were male and 70 were females. The patients were categorized into two classes according to severity of sign symptoms like puerperal rash on the body. The classes are dengue fever (DF) and dengue hemorrhagic fever (DHF). The total number of DF cases was 28.50% (57/200) and number of DHF cases was 71.50% (143/200). The patients of DHF group were found to have more liver derangement that is 90.20% (128/200) while the patients belonging to DF group were at a less risk for impairment of liver function that is 9.80% (15/200). The patients with dengue hemorrhagic fever are more prone to have liver enzyme derangement and it has a direct relation with the titer IgM in the body of patients infected with dengue virus. The liver enzyme which are found to be more raised are serum ALT and AST while serum alkaline phosphatase and serum bilirubin are not markedly raised.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"90 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79651979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.18488/JOURNAL.98/2014.1.1/98.1.13.17
Manu Rathee, Mohaneesh Bhoria
Saliva, a biologic fluid, recently has been a boon in the field of diagnostic science, as the presence of viable biomarkers in saliva elaborate its applications in multiplexed assays, disease diagnosis, clinical monitoring and for clinical decisions of patient care. Application of saliva in diagnosis is undeniable as ease in sample collection and conventional procedure. This article provides emerging evidence to provide an overview of salivary diagnostics in various fields of diagnosis and affirm its application as diagnostic Bio-Fluid.
{"title":"APPLICATION OF SALIVA AS DIAGNOSTIC BIO-FLUID- AN OVERVIEW","authors":"Manu Rathee, Mohaneesh Bhoria","doi":"10.18488/JOURNAL.98/2014.1.1/98.1.13.17","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2014.1.1/98.1.13.17","url":null,"abstract":"Saliva, a biologic fluid, recently has been a boon in the field of diagnostic science, as the presence of viable biomarkers in saliva elaborate its applications in multiplexed assays, disease diagnosis, clinical monitoring and for clinical decisions of patient care. Application of saliva in diagnosis is undeniable as ease in sample collection and conventional procedure. This article provides emerging evidence to provide an overview of salivary diagnostics in various fields of diagnosis and affirm its application as diagnostic Bio-Fluid.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"12 1","pages":"13-17"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73187182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.18488/JOURNAL.98/2014.1.2/98.2.42.46
A. Mouhsine, H. Sallahi, A. Belkouch, E. Atmane, Redouane Rokhssi, Y. Berrada, Khalid Koulali, L. Belyamani, A. Elfikri, M. Mahfoudi
Chondrosarcomas are frequent bone tumors, just after osteosarcomas, they represent 11 to 22% of all bone tumors. Proximal humerus localization occurs in about 9% of cases, the clinical picture is variable, imagery helps to establish the diagnosis, to give an exact lesion assessment and to guide therapeutic attitude and post treatment control. Confirmation is set by histology. We highlight through this case presentation clinical and radiological aspects of these tumors.
{"title":"CHONDROSARCOMA OF THE UPPER EXTREMITY OF THE HUMERUS: A CASE REPORT","authors":"A. Mouhsine, H. Sallahi, A. Belkouch, E. Atmane, Redouane Rokhssi, Y. Berrada, Khalid Koulali, L. Belyamani, A. Elfikri, M. Mahfoudi","doi":"10.18488/JOURNAL.98/2014.1.2/98.2.42.46","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2014.1.2/98.2.42.46","url":null,"abstract":"Chondrosarcomas are frequent bone tumors, just after osteosarcomas, they represent 11 to 22% of all bone tumors. Proximal humerus localization occurs in about 9% of cases, the clinical picture is variable, imagery helps to establish the diagnosis, to give an exact lesion assessment and to guide therapeutic attitude and post treatment control. Confirmation is set by histology. We highlight through this case presentation clinical and radiological aspects of these tumors.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"13 1","pages":"42-46"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78212688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.18488/JOURNAL.98/2014.1.1/98.1.1.5
N. PurnachandraraoNaik., A. Ravikiran, Y. Samata, A. Vijaykumar
Dentigerous cyst is an epithelial-lined developmental crater that encloses the crown of an unerupted tooth at the cementoenamel junction. Bilateral or multiple dentigerous cysts are often associated with few syndromes. Even though dentigerous cysts are common developmental cysts, bilateral occurrence of dentigerous cysts are extremely uncommon and to date, only 22 cases have been reported in literature till 2011. In English based language literature review, we only found nine reports of non-syndromic bilateral dentigerous cyst associated with mandibular third molars. The present article report a case of bilateral non-syndromic, dentigerous cysts associated with inverted mandibular third molars in a 25 years old male patient with brief review of literature.
{"title":"Non Syndromic, Bilateral, Dentigerous Cysts Associated with Inverted Mandibular Third Molars: A Case Report","authors":"N. PurnachandraraoNaik., A. Ravikiran, Y. Samata, A. Vijaykumar","doi":"10.18488/JOURNAL.98/2014.1.1/98.1.1.5","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2014.1.1/98.1.1.5","url":null,"abstract":"Dentigerous cyst is an epithelial-lined developmental crater that encloses the crown of an unerupted tooth at the cementoenamel junction. Bilateral or multiple dentigerous cysts are often associated with few syndromes. Even though dentigerous cysts are common developmental cysts, bilateral occurrence of dentigerous cysts are extremely uncommon and to date, only 22 cases have been reported in literature till 2011. In English based language literature review, we only found nine reports of non-syndromic bilateral dentigerous cyst associated with mandibular third molars. The present article report a case of bilateral non-syndromic, dentigerous cysts associated with inverted mandibular third molars in a 25 years old male patient with brief review of literature.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"8 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84183781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.18488/JOURNAL.98/2014.1.2/98.2.28.41
A. Berezin, A. Kremzer
The objectiveof this study was to assess an interrelationship serum RANKL/OPG complex with counts of circulating pro-angiogenic endothelial progenitor cells (EPCs) labeled as CD14+CD309+, and CD14+CD309+Tie2+ in patients with ischemic chronic heart failure (CHF).Methods: The study retrospectively evolved 153 patients (86 males) aged 48 to 62 years with exiting proven stable coronary artery disease (CAD). Systolic or diastolic CHF was defined among 109 (71.2%) patients. Twenty five 25 individuals were included in the control group. Circulating RANKL (sRANKL) and OPG were measured by high-sensitive ELISA kit at baseline. EPC populations were labeled by flow cytofluorimetry per High-Definition Fluorescence Activated Cell Sorter methodology.Results: Numerous of EPCs with phenotypes of CD14+CD309+ and CD14+CD309+Tie2+ were significantly lower in CAD patients when compared with healthy subjects. The trend to significant decrease of EPC numerous depending presence of CHF was found. The sRANKLlevel, OPG level, and sRANKL / OPG ratio were significantly higher in CHF subjects as compared to those without CHF (P=0.001). On multivariate analysis, CHF, sRANKL/OPG ratio, OPG, and NT-pro-BNP remained as independent predictors of decreased EPCs with phenotypes of CD14+CD309+ and CD14+CD309+Tie2+. When sRANKL/OPG ratio was added to the standard predictive model (CHF) improved relative integrated discrimination indices by 12.5% for CD14+CD309+ depletion, as well as by 17.3% for CD14+CD309+Tie2+depletion were found. Conclusion: We found that sRANKL/OPG ratio remained statistically significant predictor for depletion of pro-angiogenicEPCsin CAD patients.
{"title":"SERUM RANKL/OSTEOPROTEGERIN COMPLEX AND ENDOTHELIAL PROGENITOR CELLS IN CHRONIC HEART FAILURE","authors":"A. Berezin, A. Kremzer","doi":"10.18488/JOURNAL.98/2014.1.2/98.2.28.41","DOIUrl":"https://doi.org/10.18488/JOURNAL.98/2014.1.2/98.2.28.41","url":null,"abstract":"The objectiveof this study was to assess an interrelationship serum RANKL/OPG complex with counts of circulating pro-angiogenic endothelial progenitor cells (EPCs) labeled as CD14+CD309+, and CD14+CD309+Tie2+ in patients with ischemic chronic heart failure (CHF).Methods: The study retrospectively evolved 153 patients (86 males) aged 48 to 62 years with exiting proven stable coronary artery disease (CAD). Systolic or diastolic CHF was defined among 109 (71.2%) patients. Twenty five 25 individuals were included in the control group. Circulating RANKL (sRANKL) and OPG were measured by high-sensitive ELISA kit at baseline. EPC populations were labeled by flow cytofluorimetry per High-Definition Fluorescence Activated Cell Sorter methodology.Results: Numerous of EPCs with phenotypes of CD14+CD309+ and CD14+CD309+Tie2+ were significantly lower in CAD patients when compared with healthy subjects. The trend to significant decrease of EPC numerous depending presence of CHF was found. The sRANKLlevel, OPG level, and sRANKL / OPG ratio were significantly higher in CHF subjects as compared to those without CHF (P=0.001). On multivariate analysis, CHF, sRANKL/OPG ratio, OPG, and NT-pro-BNP remained as independent predictors of decreased EPCs with phenotypes of CD14+CD309+ and CD14+CD309+Tie2+. When sRANKL/OPG ratio was added to the standard predictive model (CHF) improved relative integrated discrimination indices by 12.5% for CD14+CD309+ depletion, as well as by 17.3% for CD14+CD309+Tie2+depletion were found. Conclusion: We found that sRANKL/OPG ratio remained statistically significant predictor for depletion of pro-angiogenicEPCsin CAD patients.","PeriodicalId":15645,"journal":{"name":"Journal of Diagnostics","volume":"61 1","pages":"28-41"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72978724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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