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Identification of Predictive Factors for Massive Transfusion Activation in Trauma Patients: A Systematic Review and Meta-analysis.
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-28 DOI: 10.4103/jets.jets_19_24
Thosapol Ueamsaranworakul, Ratcharin Niamjumnong, Kumpol Kornthatchapong, Winchana Srivilaithon

Introduction: Acute blood loss and uncontrolled hemorrhage in trauma require quick identification and action to restore circulating volume and save the patient. These patients have the opportunity to receive massive transfusion (MT) to reduce mortality rates and avoid overtransfusion using a suitable ratio of blood components. This study aims to systematically review and analyze the predictive factors for the activation of MT protocol (MTP) in trauma patients, which is critical for improving clinical decision-making and patient outcomes.

Methods: PubMed, ScienceDirect, Cochrane, and other sources were searched for articles from 2007 to 2020. Conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, this systematic review included original studies published in English, involving trauma patients aged 15 years or older who received MTP. The risk of bias (RoB) was assessed using the RoB in Nonrandomized Studies of Interventions-I and RoB 2 tools, and statistical analysis was performed, focusing on the homogeneity of effect sizes across trials.

Results: The articles search identified a total of 424 studies. Nine studies met all inclusion criteria. The most common predictors were age, sex, systolic blood pressure (SBP), heart rate (HR), hemoglobin (Hb) levels, international normalized ratio (INR), base excess (BE), and lactate levels. The analysis showed that parameters such as SBP, HR, Hb, INR, BE, and lactate were significantly associated with the activation of MTP. However, age and sex were not significant predictors. The survival rate was notably lower in the MTP group compared to the non-MTP group. There was no evidence of publication bias.

Conclusion: Several physiological parameters: low SBP, elevated HR, reduced Hb, increased INR, diminished BE, and elevated lactate are significantly correlated with an increased likelihood of necessitating MTP in trauma patients. Among those who received MTP, the survival rate was lower compared to the non-MTP group.

{"title":"Identification of Predictive Factors for Massive Transfusion Activation in Trauma Patients: A Systematic Review and Meta-analysis.","authors":"Thosapol Ueamsaranworakul, Ratcharin Niamjumnong, Kumpol Kornthatchapong, Winchana Srivilaithon","doi":"10.4103/jets.jets_19_24","DOIUrl":"10.4103/jets.jets_19_24","url":null,"abstract":"<p><strong>Introduction: </strong>Acute blood loss and uncontrolled hemorrhage in trauma require quick identification and action to restore circulating volume and save the patient. These patients have the opportunity to receive massive transfusion (MT) to reduce mortality rates and avoid overtransfusion using a suitable ratio of blood components. This study aims to systematically review and analyze the predictive factors for the activation of MT protocol (MTP) in trauma patients, which is critical for improving clinical decision-making and patient outcomes.</p><p><strong>Methods: </strong>PubMed, ScienceDirect, Cochrane, and other sources were searched for articles from 2007 to 2020. Conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, this systematic review included original studies published in English, involving trauma patients aged 15 years or older who received MTP. The risk of bias (RoB) was assessed using the RoB in Nonrandomized Studies of Interventions-I and RoB 2 tools, and statistical analysis was performed, focusing on the homogeneity of effect sizes across trials.</p><p><strong>Results: </strong>The articles search identified a total of 424 studies. Nine studies met all inclusion criteria. The most common predictors were age, sex, systolic blood pressure (SBP), heart rate (HR), hemoglobin (Hb) levels, international normalized ratio (INR), base excess (BE), and lactate levels. The analysis showed that parameters such as SBP, HR, Hb, INR, BE, and lactate were significantly associated with the activation of MTP. However, age and sex were not significant predictors. The survival rate was notably lower in the MTP group compared to the non-MTP group. There was no evidence of publication bias.</p><p><strong>Conclusion: </strong>Several physiological parameters: low SBP, elevated HR, reduced Hb, increased INR, diminished BE, and elevated lactate are significantly correlated with an increased likelihood of necessitating MTP in trauma patients. Among those who received MTP, the survival rate was lower compared to the non-MTP group.</p>","PeriodicalId":15692,"journal":{"name":"Journal of Emergencies, Trauma, and Shock","volume":"17 4","pages":"212-220"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Real-time Feedback Guide Devices Improve the Quality of Chest Compressions in the Bystander (Naves) Provider?
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-11-05 DOI: 10.4103/jets.jets_35_24
Thamir AlSayed, Samer Al Haliq, Faisal Katbi, Mohannad Alghamdi, Mohammed Almulhim

Introduction: Cardiopulmonary resuscitation (CPR) is an important lifesaving technique that must taught to everyone. As most cardiac arrests occur outside of the hospital, training the general population in the recognition of cardiac arrest and performing high-quality CPR is vital. Thus, this study aimed to compare the chest compression quality data (rate, depth, and fraction) with and without the use of feedback devices during CPR.

Methods: A crossover observational study was carried out at a tertiary hospital in September 2021. Five hundred and seventeen 1st-year university students were recruited, and the response rate was 90% (465). A feedback device was used to collect data. The data were numerically coded and statistical software (SPSS 21) was used to perform descriptive and inferential statistical analysis, including a paired t-test.

Results: The mean compression rate with feedback was statistically significantly lower after performing one cycle of CPR (mean difference: -5.610; 95% confidence interval [CI]= -7.987--3.233; P < 0.001), the difference between mean compression depth with and without feedback was not statistically significant (mean difference: = -0.006; 95% CI = -0.190-0.177; P = 0.944), and the mean compression target (%) with feedback was statistically significantly higher (mean difference: -15.951; 95% CI = -17.894--14.009; P < 0.001).

Conclusions: We found that the use of feedback devices during layperson-simulated CPR scenarios significantly improved the quality of chest compression in terms of depth and rate and resulted in more guidelines adherence. Moreover, national programs for CPR education should be implemented.

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引用次数: 0
Intestinal Ischemia Unveiling Takayasu Arteritis: A Rare Encounter.
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-11-14 DOI: 10.4103/jets.jets_53_24
Dhamodhara Kannan Shivarajan, Bhupendra Mehra, Soumya Ghoshal, Siddharth P Dubhashi
{"title":"Intestinal Ischemia Unveiling Takayasu Arteritis: A Rare Encounter.","authors":"Dhamodhara Kannan Shivarajan, Bhupendra Mehra, Soumya Ghoshal, Siddharth P Dubhashi","doi":"10.4103/jets.jets_53_24","DOIUrl":"10.4103/jets.jets_53_24","url":null,"abstract":"","PeriodicalId":15692,"journal":{"name":"Journal of Emergencies, Trauma, and Shock","volume":"17 4","pages":"248-249"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Spontaneous Regression of Traumatic Subdural Hematoma.
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-30 DOI: 10.4103/jets.jets_46_24
Prashant Punia, Ashish Chugh, Sarang Gotecha, Neeraj Singh, Jayant Gaud, Ishant Rege, Ramis Abdul Aziz

Acute subdural hematoma (ASDH) is a type of intracranial hemorrhage and is due to the collection of blood below the inner layer of the dura but external to the brain and arachnoid membrane. It tends to occur in the temporal parietal regions. Early intervention is the key for better outcome of the patient. Management depends on neurological status and imaging. Large SDH collects along the convexity of the brain causing compression over the brain stem with midline shift. In cases of conservatively managed ASDH, spontaneous resolution usually takes weeks to months depending on the size of the bleed. In rare cases, spontaneous rapid resolution of the SDH occurs. So here, we are presenting an 11-month-old baby girl who was brought to our Emergency room/department (ER) with a history of fall and computed tomography scan was suggestion of an ASDH in the left temporoparietal region which resolves on its own in 6 h which is a rare phenomenon and needs to be highlighted.

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引用次数: 0
Mitigating Latent Safety Threats in Cardiac Arrest Management: The Role of Simulation-based Training.
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-09-19 DOI: 10.4103/jets.jets_98_24
Hritika Sharma, Kalyani S Thakare
{"title":"Mitigating Latent Safety Threats in Cardiac Arrest Management: The Role of Simulation-based Training.","authors":"Hritika Sharma, Kalyani S Thakare","doi":"10.4103/jets.jets_98_24","DOIUrl":"10.4103/jets.jets_98_24","url":null,"abstract":"","PeriodicalId":15692,"journal":{"name":"Journal of Emergencies, Trauma, and Shock","volume":"17 4","pages":"251-252"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: Barriers to Effective Prehospital and Hyperacute Stroke Care in India: A Physician Perspective. 勘误:印度院前和急性卒中有效救治的障碍:医生的视角。
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-09-27 DOI: 10.4103/jets.jets_128_24

[This corrects the article on p. 129 in vol. 17.].

[这是对第 17 卷第 129 页文章的更正]。
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引用次数: 0
Triad of Clubbing, Boot-shaped Heart, and Brain Abscess in Tetralogy of Fallot. 法洛氏四联症的三联症:跛行、靴状心和脑脓肿。
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-08-02 DOI: 10.4103/jets.jets_21_24
Anterpreet Kaur, Harpreet Singh, Deba Prasad Dhibar
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引用次数: 0
What is the Optimal Treatment Protocol for Traumatic Popliteal Artery Injury? A Comparative Study between Two Institutions. 创伤性腘动脉损伤的最佳治疗方案是什么?两家医疗机构的比较研究。
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-09-20 DOI: 10.4103/jets.jets_164_23
Sadaki Mitsuzawa, Shinnosuke Yamashita, Yoshihiro Tsukamoto, Hisataka Takeuchi, Satoshi Ota, Eijiro Onishi, Kenji Kusakabe, Shota Nakao, Tetsuya Matsuoka, Tadashi Yasuda

Introduction: While rare, popliteal artery injury is a potentially devastating complication of knee trauma. Delayed diagnosis or inadequate management of popliteal artery injury can result in limb ischemia, amputation, and long-term disability. This study aimed to compare the treatment outcomes of popliteal artery injury between different medical centers and to reconsider the optimal protocol at our institution.

Methods: Medical records of patients sustaining traumatic popliteal artery injury from 2011 to 2022 at two institutions (one hospital: Group A; the other hospital: Group B) were retrospectively reviewed. Demographic data, radiological assessment, time course and content of initial treatment, clinical outcomes, and follow-up period were recorded.

Results: Group A included seven patients (dislocations, n = 3; fractures, n = 2; and glass penetration injuries, n = 2), with a mean follow-up period of 39 months. Group B included five patients (dislocations, n = 3 and fractures, n = 2), with a mean follow-up period of 36 months. Two patients in Group A and four patients in Group B exhibited contrast-medium resumption (average deficit: 57 mm and 60 mm, respectively). The time from injury to reperfusion was significantly shorter in Group A than in Group B (300 min vs. 749 min, P < 0.05). Group A underwent four temporary vascular shunting procedures, four external fixations, six fasciotomies, and five bypass grafting procedures. In Group B, temporary vascular shunt (TVS) was not used in any patient; however, three, two, and three patients underwent external fixation, fasciotomy, and bypass grafting, respectively. One patient in each group required above-the-knee amputation. The mean Lysholm score was 80.4 points in Group A and 72.0 points in Group B.

Conclusions: TVS considerably reduces the reperfusion time. Various options for the content and sequence of treatment must be carefully considered in advance. Early diagnosis, prompt intervention, and comprehensive management can improve the quality of care and patient outcomes.

简介腘动脉损伤虽然罕见,但可能是膝关节创伤的一种破坏性并发症。腘动脉损伤的诊断延迟或处理不当会导致肢体缺血、截肢和长期残疾。本研究旨在比较不同医疗中心对腘动脉损伤的治疗效果,并重新考虑本院的最佳治疗方案:方法:回顾性分析两家医院(一家医院:A 组;另一家医院:B 组)2011 年至 2022 年期间外伤性腘动脉损伤患者的病历。记录了人口统计学数据、放射学评估、初始治疗的时间过程和内容、临床结果和随访时间:结果:A组包括7名患者(脱臼,3人;骨折,2人;玻璃穿透伤,2人),平均随访时间为39个月。B 组包括五名患者(脱臼,n = 3;骨折,n = 2),平均随访时间为 36 个月。A 组的两名患者和 B 组的四名患者出现造影剂恢复(平均缺损分别为 57 毫米和 60 毫米)。从损伤到再灌注的时间,A 组明显短于 B 组(300 分钟对 749 分钟,P < 0.05)。A 组进行了四次临时血管分流术、四次外固定术、六次筋膜切开术和五次旁路移植术。在 B 组中,所有患者均未使用临时血管分流术(TVS),但分别有三名、两名和三名患者接受了外固定术、筋膜切开术和旁路移植术。每组中都有一名患者需要进行膝上截肢手术。A 组的平均 Lysholm 评分为 80.4 分,B 组为 72.0 分:TVS大大缩短了再灌注时间。结论:TVS 大大缩短了再灌注时间,必须事先仔细考虑治疗内容和顺序的各种选择。早期诊断、及时干预和综合管理可提高护理质量和患者预后。
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引用次数: 0
Erratum: Transfusion Practices in Severely Injured Patients at a Level 1 Trauma Center. 勘误:一级创伤中心严重受伤患者的输血实践。
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-09-27 DOI: 10.4103/jets.jets_104_24

[This corrects the article on p. 84 in vol. 17, PMID: 39070866.].

[此处更正了第 17 卷第 84 页的文章,PMID:39070866]。
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引用次数: 0
A Systematic Review and Meta-Analysis of Prehospital Plasma Administration for Hemorrhagic Shock. 院前血浆管理治疗失血性休克的系统性回顾和 Meta 分析。
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-08-28 DOI: 10.4103/jets.jets_124_23
Nasser A AlJoaib, Faisal A AlGhamdi, Annas Ghafoor, Fandi Z AlAnazi, Nisreen H Maghraby

Introduction: Hemorrhagic shock demands swift intervention. Management involves the rapid infusion of blood products to restore circulation and uphold tissue perfusion. The aim of this study was to evaluate the effectiveness of prehospital plasma administration in trauma patients, comparing outcomes with normal saline. This was a meta-analysis of randomized controlled trials.

Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline, searches were conducted in PubMed, MEDLINE, and the Cochrane Central Register of Controlled Trials from August 1, 2018, to April 4, 2023. The PubMed search string included terms related to blood plasma, prehospital care, emergency medical services, and hemorrhagic shock: (Blood Plasma [MeSH Terms] OR fresh frozen plasma [MeSH Terms] OR plasma OR fresh frozen plasma OR FFP) AND (Prehospital OR emergency care, prehospital [MeSH Terms] OR prehospital emergency care [MeSH Terms] OR prehospital OR prehospital OR EMS OR emergency medical service [MeSH Terms]) AND (hemorrhagic shock [MeSH Terms] OR hemorrhage OR hemorrhage OR hemorrhagic shock OR hemorrhagic shock). Results from the trials were pooled using a random effects model, presented as risk ratios with 95% confidence intervals.

Results: In the analysis of 760 patients from three studies, outcomes included mortality at 24 h and 28 days, multi-organ failure (MOF), acute lung injury, and vasopressor use within 24 h. Patients were divided into plasma (363) and normal saline (397) groups.

Conclusion: There is no distinction between prehospital plasma administration and normal saline concerning mortality at 24 and 28 days or the need for vasopressors within 24 h. Moreover, plasma administration did not appear to influence rates of acute lung injury or MOF.

简介失血性休克需要迅速干预。处理方法包括快速输注血液制品,以恢复血液循环和维持组织灌注。本研究旨在评估创伤患者院前输注血浆的效果,并将结果与正常生理盐水进行比较。这是一项随机对照试验的荟萃分析:根据《系统综述和荟萃分析首选报告项目》指南,从2018年8月1日至2023年4月4日在PubMed、MEDLINE和Cochrane对照试验中央注册中心进行了检索。PubMed检索字符串包括与血浆、院前护理、紧急医疗服务和失血性休克相关的术语:(血浆[MeSH术语]或新鲜冷冻血浆[MeSH术语]或血浆或新鲜冷冻血浆或FFP)和(院前或急救,院前[MeSH术语]或院前急救[MeSH术语]或院前或院前或EMS或紧急医疗服务[MeSH术语])和(失血性休克[MeSH术语]或出血或出血性休克或失血性休克)。试验结果采用随机效应模型进行汇总,以风险比和 95% 置信区间表示:在对三项研究中的 760 名患者进行的分析中,结果包括 24 小时和 28 天内的死亡率、多器官功能衰竭(MOF)、急性肺损伤和 24 小时内使用血管加压器的情况,患者分为血浆组(363 人)和生理盐水组(397 人):结论:在 24 天和 28 天的死亡率或 24 小时内使用血管加压药方面,院前血浆和生理盐水没有区别。
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Journal of Emergencies, Trauma, and Shock
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