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In Solid Organ Injury Patients Requiring Blood Transfusion, Hemostatic Procedures are Associated with Improved Survival Over Observation. 在需要输血的实体器官损伤患者中,止血程序与观察后生存率的提高有关。
IF 1.4 Q2 Medicine Pub Date : 2023-04-01 Epub Date: 2023-05-23 DOI: 10.4103/jets.jets_146_22
Jessicah A Respicio, John Culhane

Introduction: Selective nonoperative management (NOM) is the standard of care for blunt solid organ injury (SOI). Hemodynamic instability is a contraindication for NOM, but it is unclear whether the need for blood transfusion should be a criterion for instability. This study looks at the outcome of blood-transfused SOI patients to determine whether NOM is safe for this group.

Methods: This is a retrospective cohort study using the National Trauma Data Bank years 2017 through 2019. We selected patients with blunt liver, spleen, and kidney injuries. Within this group, we compared the mortality for those managed with NOM versus the hemostatic procedures of laparotomy and angioembolization. Significance for univariate analysis is tested with Chi-square for categorical variables. Multivariate analysis is performed with Cox proportional hazards regression with time-dependent covariate.

Results: 108,718 (3.5%) patients for the years 2017 through 2019 had a SOI. 20,569 (18.9%) of these received at least one unit of packed red blood cells (PRBCs) within the first 4 h. Of the SOI patients who received blood, 8264 (40.2%) underwent laparotomy only, 2924 (14.2%) underwent embolization only, and 1119 (5.4%) underwent both procedures. The adjusted odds ratios (ORs) of death for transfused SOI patients who underwent laparotomy only, embolization only, and both procedures are 0.93 (P = not significant), 0.27 (P < 0.001), and 0.48 (P < 0.001), respectively. The ORs of death with laparotomy for patients receiving >1 through 4 units are 0.87, 0.78, 0.75, and 0.72, respectively (P ≤ 0.01 for all). For embolization, the ORs are 0.27, 0.30, 0.30, and 0.30, respectively (P < 0.001 for all).

Conclusion: Laparotomy is independently associated with survival for patients who receive >1 unit of PRBCs. Angioembolization is independently associated with survival for the entire cohort, including transfused patients. Given the protective association of laparotomy in the blood-transfused SOI group, need for blood transfusion should be considered a meaningful index of instability and a relative indication for laparotomy. The protective association with angioembolization supports current practices for angioembolization of high-risk patients in the transfused and nontransfused groups.

引言:选择性非手术治疗(NOM)是治疗钝性实体器官损伤(SOI)的标准。血液动力学不稳定是NOM的禁忌症,但尚不清楚是否需要输血作为不稳定的标准。这项研究观察了输血SOI患者的结果,以确定NOM对这一群体是否安全。方法:这是一项使用2017年至2019年国家创伤数据库的回顾性队列研究。我们选择了肝、脾和肾钝性损伤的患者。在这一组中,我们比较了NOM与剖腹手术和血管栓塞止血程序的死亡率。单变量分析的显著性用分类变量的卡方检验。多变量分析采用含时协变量的Cox比例风险回归。结果:2017年至2019年,108718名(3.5%)患者患有SOI。其中20569人(18.9%)在最初4小时内接受了至少一个单位的填充红细胞(PRBCs)。在接受血液治疗的SOI患者中,8264人(40.2%)仅接受了剖腹手术,2924人(14.2%)仅接受栓塞治疗,1119人(5.4%)同时接受了两种手术。仅接受剖腹手术、仅接受栓塞和同时接受两种手术的输注SOI患者的调整后死亡优势比(OR)分别为0.93(P=不显著)、0.27(P<0.001)和0.48(P<001)。接受>1至4个单位的患者剖腹手术死亡的OR分别为0.87、0.78、0.75和0.72(所有患者的P≤0.01)。对于栓塞,ORs分别为0.27、0.30、0.30和0.30(P均<0.001)。结论:对于接受>1单位PRBCs的患者,剖腹产术与生存率独立相关。血管栓塞与整个队列(包括输血患者)的生存率独立相关。考虑到输血SOI组剖腹手术的保护性关联,输血需求应被视为一个有意义的不稳定性指标和剖腹手术的相对指征。与血管栓塞的保护性关联支持目前对输血组和非输血组高危患者进行血管栓塞的实践。
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引用次数: 1
Severe Hypercalcemia due to Drowning in an Onsen (Hot Spring). 温泉溺水引起的严重高钙血症。
IF 1.4 Q2 Medicine Pub Date : 2023-04-01 Epub Date: 2023-02-24 DOI: 10.4103/jets.jets_78_22
Daisuke Ueno, Yasukazu Shiino, Jiro Takahashi, Takahiro Inoue

Hypercalcemia is generally caused by primary hyperparathyroidism, malignancies, and drugs. Herein, we report a case of severe hypercalcemia due to drowning in hot springs. A 55-year-old woman was found floating in a public bath at a hotel and was admitted to a nearby hospital. The patient was intubated because of hypoxia and shock, and noradrenaline was titrated. Computed tomography revealed bilateral aspiration pneumonia. Blood tests revealed hypercalcemia (serum total calcium [Ca]: 18.7 mg/dL). Hyperparathyroidism, malignancy, and drug-related factors were ruled out as the causes of hypercalcemia. In addition, the public bath in which the patient drowned contained high concentrations of Ca. We concluded that the reason for hypercalcemia was accidental ingestion of the hot spring water containing a high concentration of Ca through the gastrointestinal tract. In the case of drowning and hypercalcemia, the cause may be clarified by examining the components that were accidentally swallowed.

高钙血症通常由原发性甲状旁腺功能亢进、恶性肿瘤和药物引起。在此,我们报告一例因在温泉中溺水而导致的严重高钙血症。一名55岁的女子被发现漂浮在一家酒店的公共浴池中,随后被送往附近的医院。患者因缺氧和休克而插管,并滴定去甲肾上腺素。电脑断层扫描显示双侧吸入性肺炎。血液检查显示高钙血症(血清总钙[Ca]:18.7mg/dL)。甲状旁腺功能亢进、恶性肿瘤和药物相关因素被排除为高钙血症的病因。此外,患者溺水的公共浴池中含有高浓度的钙。我们得出结论,高钙血症的原因是通过胃肠道意外摄入了含有高浓度钙的温泉水。在溺水和高钙血症的情况下,可以通过检查意外吞咽的成分来澄清原因。
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引用次数: 0
Direct versus Video Laryngoscopy during Simulated Mechanical Chest Compressions: A Randomized Crossover Trial. 模拟机械胸部按压过程中的直接喉镜检查与视频喉镜检查:一项随机交叉试验。
IF 1.4 Q2 Medicine Pub Date : 2023-01-01 Epub Date: 2023-03-24 DOI: 10.4103/jets.jets_119_22
Andrew Roberts, John Herrick, K Tom Xu, Peter Richman
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引用次数: 0
Removing Barriers to Emergency Medicine Point-of-Care Ultrasound: Illustrated by a Roadmap for Emergency Medicine Point-of-Care Ultrasound Expansion in India 消除急诊医学点护理超声的障碍:以印度急诊医学点护理超声扩展路线图为例
Q2 Medicine Pub Date : 2023-01-01 DOI: 10.4103/jets.jets_50_23
Mike Smith, S. Vimal Krishnan, Andrew Leamon, Sagar Galwankar, Tej Prakash Sinha, Vijaya Arun Kumar, Jeffrey V. Laere, John Gallien, Sanjeev Bhoi
Point-of-care ultrasound (PoCUS) has a potentially vital role to play in emergency medicine (EM), whether it be in high-, medium-, or low-resourced settings. However, numerous barriers are present which impede EM PoCUS implementation nationally and globally: (i) lack of a national practice guideline or scope of practice for EM PoCUS, (ii) resistance from non-PoCUS users of ultrasound imaging (USI) and lack of awareness from those who undertake parallel or post-EM patient care, and (iii) heterogeneous pattern of resources available in different institutes and settings. When combined with the Indian Preconception and Prenatal Diagnostic Techniques (PCPNDT) Act, this has led to the majority of India’s 1.4 billion citizens being unable to access EM PoCUS. In order to address these barriers (globally as well as with specific application to India), this article outlines the three core principles of EM PoCUS: (i) the remit of the EM PoCUS USI must be well defined a priori , (ii) the standard of EM PoCUS USI must be the same as that of non-PoCUS users of USI, and (iii) the imaging performed should align with subsequent clinical decision-making and resource availability. These principles are contextualized using an integrated PoCUS framework approach which is designed to provide a robust foundation for consolidation and expansion across different PoCUS specialisms and health-care settings. Thus, a range of mechanisms (from optimization of clinical practice through to PoCUS educational reform) are presented to address such barriers. For India, these are combined with specific mechanisms to address the PCPNDT Act, to provide the basis for influencing national legislation and instigating an addendum to the Act. By mapping to the recent Lancet Commission publication on transforming access to diagnostics, this provides a global and cross-discipline perspective for the recommendations.
无论是在高、中、低资源环境中,即时超声(PoCUS)在急诊医学(EM)中都具有潜在的重要作用。然而,目前有许多障碍阻碍了EM PoCUS在全国和全球范围内的实施:(i)缺乏EM PoCUS的国家实践指南或实践范围,(ii)非PoCUS超声成像(USI)用户的抵制,以及那些承担平行或EM后患者护理的人缺乏意识,以及(iii)不同研究所和环境中可用资源的异质性模式。结合印度孕前和产前诊断技术(PCPNDT)法案,这导致印度14亿公民中的大多数人无法获得EM PoCUS。为了解决这些障碍(全球以及在印度的具体应用),本文概述了EM PoCUS USI的三个核心原则:(i) EM PoCUS USI的职权范围必须事先明确定义,(ii) EM PoCUS USI的标准必须与USI的非PoCUS用户的标准相同,(iii)所执行的成像应与后续临床决策和资源可用性保持一致。这些原则采用综合的PoCUS框架方法,旨在为不同的PoCUS专业和保健环境之间的巩固和扩展提供坚实的基础。因此,提出了一系列机制(从优化临床实践到PoCUS教育改革)来解决这些障碍。对印度来说,这些措施与具体机制相结合,以处理《预防和危害野生动物法》,为影响国家立法和促成该法案增编提供基础。通过与《柳叶刀》委员会最近发表的关于转变诊断方法可及性的出版物相结合,这为这些建议提供了一个全球和跨学科的视角。
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引用次数: 0
Pattern of Presentation and Outcome of Adult Patients with Abdominal Trauma - A 7-Year Retrospective Study in a Nigerian Tertiary Hospital. 成年腹部创伤患者的表现模式和预后——尼日利亚一家三级医院的7年回顾性研究。
IF 1.2 Q3 EMERGENCY MEDICINE Pub Date : 2023-01-01 Epub Date: 2023-02-24 DOI: 10.4103/jets.jets_91_22
Adedire Timilehin Adenuga, Ademola Adeyeye

Introduction: Abdominal trauma is a major cause of morbidity and mortality in low- and middle-income countries. There is a paucity of trauma data in this region and this study aimed to show the pattern of presentation and outcome of patients with abdominal trauma at a North-Central Nigerian Teaching Hospital.

Methods: This was a retrospective, observational study of patients with abdominal trauma who presented at the University of Ilorin Teaching Hospital from January 2013 to December 2019. Patients with clinical and/or radiological evidence of abdominal trauma were identified, and data extracted and analyzed.

Results: A total of 87 patients were included in the study. There were 73 males and 14 females (5.2:1) with a mean age of 34.2 years. Blunt abdominal injury occurred in 53 (61%) patients with 10 patients (11%) having concomitant extra-abdominal injuries. A total of 105 abdominal organ injuries occurred in 87 patients with the small bowel being the most frequently injured organ in penetrating trauma, while in blunt abdominal injury, the spleen was most commonly injured. A total of 70 patients (80.5%) had emergency abdominal surgery with a morbidity rate of 38.6% and negative laparotomy rate of 2.9%. There were 15 deaths in the period accounting for 17% of patients with sepsis as the most common cause of death (66%). Shock at presentation, late presentation >12 h, need for perioperative intensive care unit admission, and repeat surgery were associated with a higher risk of mortality (P < 0.05).

Conclusion: Abdominal trauma in this setting is associated with a significant amount of morbidity and mortality. Typical patients present late and with poor physiologic parameters often resulting in an undesirable outcome. There should be steps targeted at preventive policies focused on reducing the incidence of road traffic crashes, terrorism, and violent crimes as well as improving health care infrastructure to cater to this specific group of patients.

引言:腹部创伤是中低收入国家发病率和死亡率的主要原因。该地区缺乏创伤数据,本研究旨在显示尼日利亚中北部教学医院腹部创伤患者的表现模式和结果。方法:这是一项对2013年1月至2019年12月在伊洛林大学教学医院就诊的腹部创伤患者进行的回顾性观察性研究。确定有腹部创伤临床和/或放射学证据的患者,并提取和分析数据。结果:本研究共纳入87例患者。其中男性73人,女性14人(5.2:1),平均年龄34.2岁。钝性腹部损伤发生在53名(61%)患者中,其中10名患者(11%)伴有腹部外损伤。87名患者共发生105例腹部器官损伤,小肠是穿透性创伤中最常见的损伤器官,而在钝性腹部损伤中,脾脏最常见。共有70名患者(80.5%)接受了紧急腹部手术,发病率为38.6%,剖腹探查阴性率为2.9%。在此期间有15人死亡,占败血症患者最常见死亡原因的17%(66%)。出现休克、迟发>12h、需要围手术期重症监护室入院和重复手术与较高的死亡率相关(P<0.05)。结论:这种情况下的腹部创伤与大量的发病率和死亡率相关。典型的患者出现较晚且生理参数较差,通常会导致不良结果。应采取措施,制定预防性政策,重点是减少道路交通事故、恐怖主义和暴力犯罪的发生率,并改善医疗保健基础设施,以满足这一特定患者群体的需求。
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引用次数: 0
Performance of qSOFA Score as a Screening Tool for Sepsis in the Emergency Department. qSOFA评分作为脓毒症筛查工具在急诊科的应用。
IF 1.4 Q2 Medicine Pub Date : 2023-01-01 Epub Date: 2023-03-24 DOI: 10.4103/jets.jets_99_22
Atul Kumar Tiwari, Nayer Jamshed, Ankit Kumar Sahu, Akshay Kumar, Praveen Aggarwal, Sanjeev Bhoi, Roshan Mathew, Meera Ekka

Introduction: Sepsis is the leading cause of mortality, and various scoring systems have been developed for its early identification and treatment. The objective was to test the ability of quick sequential organ failure assessment (qSOFA) score to identify sepsis and predict sepsis-related mortality in the emergency department (ED).

Methods: We conducted a prospective study from July 2018 to April 2020. Consecutive patients with age ≥18 years who presented to the ED with a clinical suspicion of infection were included. Sensitivity, specificity, positive predictive value (PPV), negative predictive values (NPV), and odds ratio (OR) for sepsis related mortality on day 7 and 28 were measured.

Results: A total of 1200 patients were recruited; of which 48 patients were excluded and 17 patients were lost to follow-up. 54 (45.4%) of 119 patients with positive qSOFA (qSOFA >2) died at 7 days and 76 (63.9%) died at 28 days. A total of 103 (10.1%) of 1016 patients with negative qSOFA (qSOFA score <2) died at 7 days and 207 (20.4%) died at 28 days. Patients with positive qSOFA score were at higher odds of dying at 7 days (OR: 3.9, 95% confidence interval [CI]: 3.1-5.2, P < 0.001) and 28 days (OR: 6.9, 95% CI: 4.6-10.3, P < 0.001). The PPV and NPV with positive qSOFA score to predict 7- and 28-day mortality were 45.4%, 89.9% and 63.9%, 79.6%, respectively.

Conclusion: The qSOFA score can be used as a risk stratification tool in a resource-limited setting to identify infected patients at an increased risk of death.

引言:脓毒症是导致死亡的主要原因,已经开发了各种评分系统来早期识别和治疗脓毒症。目的是测试快速序贯器官衰竭评估(qSOFA)评分在急诊科(ED)识别败血症和预测败血症相关死亡率的能力。方法:我们于2018年7月至2020年4月进行了一项前瞻性研究。年龄≥18岁的连续患者因临床怀疑感染而就诊于急诊科。测量第7天和第28天败血症相关死亡率的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)和比值比(OR)。结果:共招募了1200名患者;其中48例被排除,17例失访。119例qSOFA阳性(qSOFA>2)患者中,54例(45.4%)在第7天死亡,76例(63.9%)在第28天死亡。在1016例qSOFA阴性(qSOFA评分P<0.001)和28天(OR:6.9,95%CI:4.6-10.3,P<0.001)的患者中,共有103例(10.1%)。qSOFA阳性的PPV和NPV预测7天和28天死亡率分别为45.4%、89.9%和63.9%、79.6%。结论:在资源有限的情况下,qSOFA评分可以作为一种风险分层工具,用于识别死亡风险增加的感染患者。
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引用次数: 0
Successful Management of an Acute Case of Orbital Cellulitis of Odontogenic Origin. 一例牙源性眼眶蜂窝组织炎急性病例的成功治疗。
IF 1.4 Q2 Medicine Pub Date : 2023-01-01 Epub Date: 2023-02-24 DOI: 10.4103/jets.jets_112_22
Bijnya Birajita Panda, Subhrasarita Behera, Shilpa Vishwanath
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引用次数: 0
Relationship between Incontinence and Disease Severity in Patients Transported by Ambulance. 救护车运送病人失禁与疾病严重程度的关系。
IF 1.4 Q2 Medicine Pub Date : 2023-01-01 Epub Date: 2023-02-24 DOI: 10.4103/jets.jets_122_22
Michika Hamada, Ikuto Takeuchi, Ken-Ichi Muramatsu, Hiroki Nagasawa, Hiromichi Ohsaka, Kouhei Ishikawa, Youichi Yanagawa

Introduction: Retrospectively investigated this relationship using data from Shimoda Fire Department.

Methods: We investigated patients who were transported by Shimoda Fire Department from January 2019 to December 2021. The participants were divided into groups based on the existence of incontinence at the scene or not (Incontinence [+] and Incontinence [-]). We compared the variables mentioned above between these groups.

Results: There were 499 cases with incontinence and 8241 cases without incontinence. There were no significant differences between the two groups with respect to weather and wind speed. The average age, percentage of male patients, percentage of cases in the winter season, rate of collapse at home, scene time, rate of endogenous disease, disease severity, and mortality rate in the incontinence (+) group were significantly greater in comparison to the incontinence (-) group, whereas the average temperature in the incontinence (+) group was significantly lower than that in the incontinence (-) group. Regarding the rates of incontinence of each disease, neurologic, infectious, endocrinal disease, dehydration, suffocation, and cardiac arrest at the scene had more than twice the rate of incontinence in other conditions.

Conclusions: This is the first study to report that patients with incontinence at the scene tended to be older, showed a male predominance, severe disease, high mortality, and required a long scene time in comparison to patients without incontinence. Prehospital care providers should therefore check for incontinence when evaluating patients.

引言:使用下田消防局的数据对这种关系进行回顾性调查。方法:我们调查了2019年1月至2021年12月由下田消防队运送的患者。根据现场是否存在失禁将参与者分为几组(失禁[+]和失禁[-])。我们比较了上述两组之间的变量。结果:尿失禁499例,无尿失禁8241例。两组在天气和风速方面没有显著差异。失禁(+)组的平均年龄、男性患者百分比、冬季病例百分比、在家崩溃率、现场时间、内源性疾病发生率、疾病严重程度和死亡率显著高于失禁(-)组,而失禁(+)组的平均温度显著低于失禁(-)组。就每种疾病的失禁率而言,神经、感染、内分泌疾病、脱水、窒息和心脏骤停在现场的失禁率是其他情况下的两倍多。结论:这是第一项报告现场失禁患者年龄较大、疾病严重、死亡率高,并且与无失禁患者相比需要较长的现场时间的研究。因此,院前护理提供者在评估患者时应检查失禁情况。
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引用次数: 0
Validity of Trauma and Injury Severity Score Scoring in India. 印度创伤和损伤严重程度评分的有效性。
IF 1.4 Q2 Medicine Pub Date : 2023-01-01 Epub Date: 2023-03-24 DOI: 10.4103/jets.jets_120_22
Vamsi Krishna Kaza, Balamurugan Nathan
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引用次数: 0
Unilateral Traumatic Adrenal Hemorrhage with Shock. 单侧外伤性肾上腺出血伴休克。
IF 1.4 Q2 Medicine Pub Date : 2023-01-01 Epub Date: 2023-02-24 DOI: 10.4103/jets.jets_37_22
Ankur Verma, Sanjay Jaiswal, Kushagra Gupta, Wasil Rasool Sheikh, Amit Vishen, Meghna Haldar, Rinkey Ahuja, Abbas Ali Khatai, Nilesh Prasad

Trauma to the adrenal glands is very rare. The variation in clinical manifestations is marked and markers for its diagnosis being limited, makes it tough to be diagnosed. Computed tomography remains the gold standard for detecting this injury. Prompt recognition and the potential for mortality with adrenal insufficiency can provide the best guidance for the treatment and care of the severely injured. We present a case of a 33-year-old trauma patient who was not responding to the management of his shock. He was finally found to have a right adrenal haemorrhage leading to adrenal crisis. The patient was resuscitated in the Emergency Department but succumbed 10 days post admission.

肾上腺损伤非常罕见。临床表现的变异是显著的,其诊断标志物有限,使其难以诊断。计算机断层扫描仍然是检测这种损伤的黄金标准。及时认识到肾上腺功能不全可能导致死亡,可以为严重受伤者的治疗和护理提供最佳指导。我们介绍了一个33岁的创伤患者的案例,他对休克的处理没有反应。他最终被发现右肾上腺出血,导致肾上腺危象。患者在急诊科进行了复苏,但在入院10天后死亡。
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引用次数: 0
期刊
Journal of Emergencies, Trauma, and Shock
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