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Burden of Antimicrobial Resistance Among Women with Post-Partum Infections in Low-Middle Income Countries: A Systematic Review. 中低收入国家产后感染妇女的抗菌药耐药性负担:系统回顾。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-17 DOI: 10.1007/s44197-024-00222-8
C. Monari, Lorenzo Onorato, Nicola Coppola, Mario C B Raviglione, G. Gon
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引用次数: 0
Antenatal Depression and its Associated Factors: Findings from Kuwait Birth Cohort Study. 产前抑郁症及其相关因素:科威特出生队列研究的结果。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1007/s44197-024-00223-7
Reem Al-Sabah, Abdullah Al-Taiar, Ali H Ziyab, Saeed Akhtar, Majeda S Hammoud
Pregnant and postpartum women are at high risk of depression due to hormonal and biological changes. Antenatal depression is understudied compared to postpartum depression and its predictors remain highly controversial.
由于荷尔蒙和生理变化,孕妇和产后妇女患抑郁症的风险很高。与产后抑郁症相比,产前抑郁症的研究不足,其预测因素仍存在很大争议。
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引用次数: 0
Correction: Incidence, Prevalence, Risk Factors, and Clinical Treatment for Children with Developmental Dysplasia of the Hip in Saudi Arabia. A Systematic Review. 更正:沙特阿拉伯髋关节发育不良儿童的发病率、流行率、风险因素和临床治疗。系统回顾。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1007/s44197-024-00224-6
Naif Z Alrashdi, Mansour M. Alotaibi, Moqfa Alharthi, F. Kashoo, Sultan Alanazi, Ahmad Alanazi, Msaad Alzhrani, Thamer S Alhussainan, Rami Alanazi, Rakan Almutairi, Matthew Ithurburn
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引用次数: 0
Multi-Trait Body Shape Phenotypes and Breast Cancer Risk in Postmenopausal Women: A Causal Mediation Analysis in the UK Biobank Cohort. 绝经后妇女的多特征体形表型与乳腺癌风险:英国生物库队列的因果中介分析。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-10 DOI: 10.1007/s44197-024-00226-4
Amina Amadou, Heinz Freisling, Anja M Sedlmeier, Patricia Bohmann, Emma Fontvieille, Andrea Weber, Julian Konzok, Michael J Stein, Laia Peruchet-Noray, Anna Jansana, Hwayoung Noh, Mathilde His, Quan Gan, Hansjörg Baurecht, Béatrice Fervers
Body shape phenotypes combining multiple anthropometric traits have been linked to postmenopausal breast cancer (BC). However, underlying biological pathways remain poorly understood. This study investigated to what extent the associations of body shapes with postmenopausal BC risk is mediated by biochemical markers. The study included 176,686 postmenopausal women from UK Biobank. Four body shape phenotypes were derived from principal component (PC) analysis of height, weight, body mass index, waist and hip circumferences, and waist-to-hip ratio (WHR). The four-way decomposition of the total effect was used to estimate mediation and interaction effects simultaneously as well as the mediated proportions. After 10.9 years median follow-up, 6,396 incident postmenopausal BC were diagnosed. There was strong evidence of positive associations between PC1 (general obesity) and PC2 (tall, low WHR), and BC risk. The association of PC1 with BC risk was positively mediated by testosterone and negatively by insulin-like growth factor-1 (IGF-1), with the overall proportion mediated (sum of the mediated interaction and pure indirect effect (PIE)) accounting for 11.4% (95% confidence intervals: 5.1 to 17.8%) and -12.2% (-20.5% to -4.0%) of the total effect, respectively. Small proportions of the association between PC2 and BC were mediated by IGF-1 (PIE: 2.8% (0.6 to 4.9%)), and sex hormone-binding globulin (SHBG) (PIE: -6.1% (-10.9% to -1.3%)). Our findings are consistent with differential pathways linking different body shapes with BC risk, with a suggestive mediation through testosterone and IGF-1 in the relationship of a generally obese body shape and BC risk, while IGF-1 and SHBG may mediate a tall/lean body shape-BC risk association.
结合多种人体测量特征的体形表型与绝经后乳腺癌(BC)有关。然而,人们对其背后的生物学途径仍然知之甚少。本研究调查了体型与绝经后乳腺癌风险之间的关联在多大程度上是由生化标志物介导的。研究对象包括英国生物库中的 176,686 名绝经后妇女。通过对身高、体重、体重指数、腰围和臀围以及腰臀比(WHR)进行主成分(PC)分析,得出了四种体型表型。总效应的四向分解用于同时估计中介效应和交互效应以及中介比例。经过 10.9 年的中位随访,共诊断出 6396 例绝经后乳腺癌。有强有力的证据表明,PC1(全身肥胖)和 PC2(身材高大、低 WHR)与 BC 风险之间存在正相关。PC1与BC风险的关系受睾酮的正向介导,受胰岛素样生长因子-1(IGF-1)的负向介导,介导的总比例(介导的相互作用和纯间接效应(PIE)之和)分别占总效应的11.4%(95%置信区间:5.1%至17.8%)和-12.2%(-20.5%至-4.0%)。IGF-1(PIE:2.8%(0.6% 至 4.9%))和性激素结合球蛋白(SHBG)(PIE:-6.1%(-10.9% 至-1.3%))在 PC2 与 BC 之间的关联中占很小比例。我们的研究结果表明,不同体型与乳腺癌风险之间存在不同的关联途径,一般肥胖体型与乳腺癌风险之间的关系可能是通过睾酮和IGF-1介导的,而IGF-1和SHBG可能介导高大/清瘦体型与乳腺癌风险之间的关系。
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引用次数: 0
Dynamic Patterns and Predominance of Respiratory Pathogens Post-COVID-19: Insights from a Two-Year Analysis. COVID-19 后呼吸道病原体的动态模式和优势:两年分析的启示。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-08 DOI: 10.1007/s44197-024-00213-9
Salma AlBahrani, Samira Jamaan AlZahrani, Thekra N Al-Maqati, Atheer Almehbash, Anfal Alshammari, Refan Bujlai, Sarah Ba Taweel, Fares Almasabi, Abdullah AlAmari, Jaffar A Al-Tawfiq
Respiratory tract infections (RTIs) stand out as the most frequent causes leading to visits to the emergency department and hospitalizations. This study aims to assess the types and prevalence of respiratory infections across two years following the end of the COVID-19 pandemic.
呼吸道感染(RTI)是导致人们到急诊科就诊和住院的最常见原因。本研究旨在评估 COVID-19 大流行结束后两年内呼吸道感染的类型和流行率。
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引用次数: 0
The Etiology of Advanced Chronic Kidney Disease in Southeast Asia: A Meta-analysis. 东南亚晚期慢性肾病的病因:元分析
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-08 DOI: 10.1007/s44197-024-00209-5
Ni Made Hustrini, Endang Susalit, Felix Firyanto Widjaja, Anandhara Indriani Khumaedi, Olaf M Dekkers, Merel van Diepen, Joris I Rotmans
Chronic kidney disease (CKD) etiology varies greatly between developed and developing countries. In addition, differences in underlying pathogenesis and therapeutic options affect the progression towards advanced-CKD. This meta-analysis aims to identify the etiology of advanced-CKD in Southeast Asia.
发达国家和发展中国家的慢性肾脏病(CKD)病因差异很大。此外,潜在发病机制和治疗方案的差异也会影响晚期 CKD 的进展。本荟萃分析旨在确定东南亚地区晚期 CKD 的病因。
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引用次数: 0
Risk of sleep disorders in patients with pneumoconiosis: a retrospective cohort study. 尘肺病患者出现睡眠障碍的风险:一项回顾性队列研究。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-04 DOI: 10.1007/s44197-024-00225-5
Yen-Sung Lin, Te-Chun Shen, Cheng-Li Lin, Chih-Yen Tu, Te-Chun Hsia, Wu-Huei Hsu, Der-Yang Cho
Pneumoconiosis is associated with pulmonary and cardiovascular diseases; however, the link between pneumoconiosis and sleep disorders is not well understood. This study aimed to investigate the connection between pneumoconiosis and subsequent risk of sleep disorders.
尘肺病与肺部和心血管疾病有关,但尘肺病与睡眠障碍之间的联系却不甚明了。本研究旨在调查尘肺病与随后的睡眠障碍风险之间的联系。
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引用次数: 0
Evolving Epidemiology of Pediatric Respiratory Syncytial Virus (RSV) Cases Around COVID-19 Pandemic: Impact and Clinical Insights, Retrospective Cohort Study. COVID-19 大流行前后小儿呼吸道合胞病毒 (RSV) 病例流行病学的演变:影响和临床见解,回顾性队列研究。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-04 DOI: 10.1007/s44197-024-00218-4
Deema Gashgarey, Mohammed Alsuhaibani, Raghad Alhuthil, Hattan Alhabshan, Azzam Alabdulqader, Rakan Badran, Abdulaziz Balhmar, Haifa Aldawood, Esam A AlBanyan, Salem AlGhamdi, Suliman AlJumaah, Ohoud AlYabes, Sami Al-Hajjar
The burden of respiratory syncytial virus (RSV) in high-risk pediatric patients remains unclear. Therefore, this study aims to characterize pediatric RSV cases from January 2019 to December 2022 and assess the impact of the COVID-19 pandemic on RSV burden and RSV-related outcomes. In addition, examining factors influencing RSV-related hospitalization.
呼吸道合胞病毒(RSV)在高危儿科患者中的负担仍不清楚。因此,本研究旨在描述 2019 年 1 月至 2022 年 12 月期间儿科 RSV 病例的特征,并评估 COVID-19 大流行对 RSV 负担和 RSV 相关结果的影响。此外,还研究了影响 RSV 相关住院治疗的因素。
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引用次数: 0
Pattern of Virtual Consultations in the Kingdom of Saudi Arabia: An Epidemiological Nationwide Study. 沙特阿拉伯王国的虚拟会诊模式:全国流行病学研究。
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-04 DOI: 10.1007/s44197-024-00219-3
Reem S AlOmar, Muaddi AlHarbi, Nijr S Alotaibi, Nouf A AlShamlan, Malak A Al-Shammari, Arwa A AlThumairi, Mona AlSubaie, Mohammed A Alshahrani, Mohammad K AlAbdulaali
In the Kingdom of Saudi Arabia (KSA), little is known about the adoption of virtual consultations (VCs), with most studies being survey-based leading to varying results. This study aims to utilise secondary collected data on the use of both kinds of VCs currently available, and to epidemiologically describe the adoption of these consultations.
在沙特阿拉伯王国 (KSA),人们对虚拟会诊 (VC) 的采用情况知之甚少,大多数研究都是以调查为基础,结果各不相同。本研究旨在利用二手收集的数据,了解目前两种虚拟会诊的使用情况,并从流行病学角度描述这些会诊的采用情况。
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引用次数: 0
A Holistic Approach to Cardiometabolic and Infectious Health in the General Population of Reunion Island: The REUNION Study. 留尼汪岛普通人群心脏代谢和感染健康的综合方法:留尼旺研究
IF 7.3 4区 医学 Q1 Medicine Pub Date : 2024-04-02 DOI: 10.1007/s44197-024-00221-9
Mohammad Ryadh Pokeerbux, Patrick Mavingui, Patrick Gérardin, Nelly Agrinier, Erick Gokalsing, Olivier Meilhac, Maxime Cournot

Introduction: Reunion Island is a French overseas department in the South West Indian Ocean with a unique multi-ethnic population. Cardiovascular diseases are the most common chronic conditions with higher prevalences of hypertension and diabetes compared to mainland France. Moreover, Reunion Island is particularly exposed to vector-borne diseases such as chikungunya and dengue. Our objective is to describe the prevalence of cardiometabolic and infectious diseases in Reunion Island and explore causal mechanisms linking these diseases.

Methods: The REUNION study is an ongoing French prospective study. From January 2022, 2,000 consenting participants (18-68 years old) are being recruited from the general population according to polling lists and random generation of cellphone number. Baseline examination consists of (i) general health examination, assessment of cardiovascular risk factors, markers of subclinical atherosclerosis, bronchial obstruction, neuropathic and autonomic dysfunction, (ii) questionnaires to determine sociodemographic characteristics, diet, exposure to vector-borne diseases, mental health and cognitive functions, social inequalities in health and ethnic origins, (iii) biological sampling for determination of cardiovascular risk factors, seroprevalence of infectious diseases, innovative lipid biomarkers, advanced omics, composition of intestinal, periodontal and skin microbiota, and biobanking.

Conclusions: The REUNION study should provide new insights into the prevalence of cardiometabolic and infectious diseases, as well as their potential associations through the examination of various environmental pathways and a wide range of health aspects.

简介留尼汪岛是西南印度洋上的一个法国海外省,拥有独特的多民族人口。心血管疾病是最常见的慢性疾病,高血压和糖尿病的发病率高于法国本土。此外,留尼汪岛尤其容易受到基孔肯雅病和登革热等病媒传播疾病的影响。我们的目标是描述留尼汪岛心脏代谢疾病和传染病的发病率,并探索这些疾病之间的因果关系:留尼旺研究是法国正在进行的一项前瞻性研究。从2022年1月起,根据投票名单和随机生成的手机号码,从普通人群中招募2000名同意参加的参与者(18-68岁)。基线检查包括:(i) 一般健康检查,评估心血管风险因素、亚临床动脉粥样硬化标志物、支气管阻塞、神经病理性和自主神经功能障碍;(ii) 问卷调查,以确定社会人口特征、饮食、接触病媒传播疾病的情况、(iii) 通过生物采样确定心血管风险因素、传染病血清流行率、创新的脂质生物标记物、先进的全息技术、肠道、牙周和皮肤微生物群的组成以及生物银行。结论:通过对各种环境途径和广泛的健康问题进行研究,REUNION 研究将为了解心血管代谢疾病和传染病的发病率及其潜在关联提供新的视角。
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Journal of Epidemiology and Global Health
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