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Safety of Breastfeeding During Favipiravir Therapy: A Case Study. 法维拉韦治疗期间母乳喂养的安全性:个案研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-26 DOI: 10.1177/08903344241296034
Yuka Sano Wada, Jumpei Saito, Wakako Yamamoto, Yuka Maegawa, Taro Kamiya, Katsumi Mizuno

Introduction: Favipiravir is a known anti-influenza agent that has been used globally, especially during the coronavirus disease 2019 (COVID-19) pandemic. This drug has been important for treating influenza and other emerging infectious diseases, although it was ultimately proven to be ineffective for COVID-19. Currently, no studies have reported the human-milk transfer of favipiravir at doses of 1,600-3,600 mg/day in the treatment of diseases, including COVID-19.

Main issue: A 38-year-old mother gave birth at 38 gestational weeks because of severe respiratory distress caused by COVID-19. Considering her illness and the inadequate information available on the safety of favipiravir in breastfeeding, she chose formula feeding for her infant. However, she still provided human milk and blood samples for the analysis of drug concentrations.

Management: Five concentrations of favipiravir in the mother's milk and four in maternal blood were measured (3.0-80.9 and 3.5-78.4 μg/ml, respectively). Metabolites of favipiravir were not measured. The relative infant dose was 15.2%. The favipiravir concentration in human milk was as high as 80.9 μg/ml at 1.3 hours after the medication was given, when maternal blood levels are considered to be at their highest; however, favipiravir concentration was low in human milk immediately before medication administration (5.9-9.7 μg/ml).

Conclusion: Breastfeeding is not contraindicated in mothers undergoing favipiravir therapy and would be safer immediately before medication. Avoiding feeding at the peak time (1.3 hours after medication) minimizes infant exposure.

简介法维拉韦是一种已知的抗流感药物,已在全球范围内使用,特别是在冠状病毒病 2019(COVID-19)大流行期间。这种药物对于治疗流感和其他新出现的传染病非常重要,尽管它最终被证明对 COVID-19 无效。目前,还没有研究报告称,在治疗包括COVID-19在内的疾病时,剂量为1,600-3,600毫克/天的法非拉韦会发生人乳转移:一位 38 岁的产妇因 COVID-19 引起的严重呼吸困难而在妊娠 38 周时分娩。考虑到她的病情以及有关母乳喂养中法非拉韦安全性的信息不足,她为婴儿选择了配方奶喂养。不过,她仍然提供了母乳和血液样本用于药物浓度分析:管理:在母亲的乳汁中测得了五种浓度的法非拉韦,在母亲的血液中测得了四种浓度的法非拉韦(分别为 3.0-80.9 和 3.5-78.4 μg/ml)。未检测到法非拉韦的代谢物。相对婴儿剂量为 15.2%。服药1.3小时后,母乳中的法非拉韦浓度高达80.9微克/毫升,此时母体血液中的法非拉韦浓度被认为是最高的;然而,服药前母乳中的法非拉韦浓度较低(5.9-9.7微克/毫升):结论:接受法非拉韦治疗的母亲并不禁忌母乳喂养,而且在用药前母乳喂养更为安全。避免在用药高峰期(用药后 1.3 小时)喂奶可最大限度地减少婴儿接触药物的机会。
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引用次数: 0
Exclusive Breastfeeding Among Tribal Mothers in India: Challenges, Cultural Beliefs, and Policy Recommendations. 印度部落母亲的纯母乳喂养:挑战、文化信仰和政策建议》。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-20 DOI: 10.1177/08903344241297598
Hetal Rathod, Kajal Srivastava, Prerna Verma, Akhil R
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引用次数: 0
Response to Letter to the Editor. 回应致编辑的信。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-29 DOI: 10.1177/08903344241288410
Chele Marmet
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引用次数: 0
About Research - Qualitative Data Collection: Photo Elicitation. 定性数据收集:照片征集。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-08 DOI: 10.1177/08903344241273863
Sara L Gill

Photo elicitation is a qualitative data collection technique in which the researcher includes photographs or other visual images as part of participant interviews. The researcher might provide the photographs or might ask the participants to bring photographs to the interview. This technique enhances the breadth and depth of verbal qualitative interviews. The use of photo elicitation can enhance the rigor of a qualitative study. There are both advantages and disadvantages of this data collection technique. Ethical issues warrant special consideration.

照片诱导是一种定性数据收集技术,在这种技术中,研究人员将照片或其他视觉图像作为参与者访谈的一部分。研究者可以提供照片,也可以要求参与者带照片参加访谈。这种技术可以增强口头定性访谈的广度和深度。使用照片诱导可以提高定性研究的严谨性。这种数据收集方法有利有弊。伦理问题值得特别考虑。
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引用次数: 0
Response to Letter to the Editor. 回应致编辑的信。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 DOI: 10.1177/08903344241288410a
Joan E Dodgson
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引用次数: 0
Letter to the Editor - Documenting Our History. 记录我们的历史
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-29 DOI: 10.1177/08903344241277797
Suzanne G Cox
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引用次数: 0
Allomilk: An Anthropogeny-Based Framework for Human Milk as a Climate Solution. 全母乳:基于人类起源的人奶气候解决方案框架。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-04 DOI: 10.1177/08903344241271344
Emily E Little

Climate change is an urgent threat to perinatal and infant health, with the greatest effects of climate change exposures being felt disproportionately by global majority communities who have been most harmed by systems of oppression. Human milk feeding is one recognized solution to bolster climate resilience. Yet, policies and practices to support human milk as a climate solution are inconsistent and under-prioritized, which is unsurprising given the lack of alignment between human history and current cultural context with regard to lactation and human milk access. This paper presents a new framework on lactation as a climate solution, which is unique in its incorporation of the critical history of cooperative breastfeeding in our species. Rooted in anthropogeny, or the study of human origins, and antiracist principles of lactation, the Allomilk Framework highlights five concepts of the ideal application of human milk as a climate solution, bridging ancient allonursing with present-day lactation and human milk access. These ideal applications-and the proposed development of measures to operationalize them-will advance the field through a shared understanding of the qualities that should be prioritized in the assessment of policies and practices at the intersection of climate resilience and human milk access. Application of the Allomilk Framework to assess and design future policies and practices will advance the field by increasing the potential for climate resilience and climate mitigation while working with-rather than against-the importance of cooperative breastfeeding in human history.

气候变化是对围产期和婴儿健康的一个紧迫威胁,全球多数族群受到压迫制度的伤害最为严重,他们不成比例地感受到气候变化暴露的最大影响。母乳喂养是一种公认的增强气候适应能力的解决方案。然而,支持母乳喂养作为气候解决方案的政策和实践并不一致,也未得到充分重视,这并不奇怪,因为在哺乳和母乳获取方面,人类历史与当前文化背景之间缺乏一致性。本文提出了一个将哺乳作为气候解决方案的新框架,其独特之处在于将人类合作母乳喂养的重要历史纳入其中。全母乳框架植根于人类起源学(即人类起源研究)和哺乳的反种族主义原则,强调了母乳作为气候解决方案的理想应用的五个概念,将古代的全母乳喂养与当今的哺乳和母乳获取联系起来。这些理想的应用--以及为将它们付诸实施而建议制定的措施--将通过对在评估气候适应性与母乳获取交叉点的政策和实践时应优先考虑的品质的共同理解,推动该领域的发展。应用 "全母乳框架 "评估和设计未来的政策与实践,将提高气候适应力和气候减缓的潜力,同时与合作母乳喂养在人类历史上的重要性相辅相成,而不是背道而驰,从而推动该领域的发展。
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引用次数: 0
Lactation Newsmakers: Documenting our History - Supporting Breastfeeding Exchange Relations by Building Equitable and Innovative Solutions: An Interview With João Aprigio Guerra de Almeida. 通过建立公平和创新的解决方案支持母乳喂养交流关系:采访 João Aprigio Guerra de Almeida。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-16 DOI: 10.1177/08903344241274325
Tanya M Cassidy, João Aprigio Guerra de Almeida

Professor Joao Aprigio Guerra de Almeida graduated in Food Engineering (UFV-1981) with a Master in Microbiology (UFV-1986) and a doctorate in Women's and Children's Health (Fiocruz/IFF, 1998) He is founder and coordinator of the Brazilian Human Milk Banks Network (Ministry of Health-Brasil/Oswaldo Cruz Foundation-Fiocruz, 1987 to 2024); Head of the National Reference Center for Human Milk Banks at the National Institute of Women, Children and Adolescent Health Fernandes Figueira-IFF (Fiocruz/IFF, 1987 to 2024); Executive Secretary of the Ibero-American Human Milk Banks Network Program (Ibero-American General Secretariat-SEGIB/Brazilian Cooperation Agency-ABC/MS-FIOCRUZ, 2008 to 2020); Coordinator of International Technical Cooperation in Human Milk Banks ABC/Fiocruz/MS (2005 to 2024); and Coordinator of the Human Milk Banks Network of the Community of Portuguese Speaking Countries - CPLP (2017 to 2024). He has been recognized with the Sasakawa Health Prize (World Health Organization [WHO], 2001); as Officer of the Order of Rio Branco (Presidency of the Federative Republic of Brazil, 2001); with Global Health Challenges and Responses of the South in Time of Crisis (WHO, 2009); as Commendator of the Order of Rio Branco-Ministry of Foreign Affairs/Presidency of the Federative Republic of Brazil (2018); and Dr LEE Jong-wook Memorial Prize for Public Health (WHO, 2020). His areas of activity include Public Health, breastfeeding, Human Milk Banks, Public Management, and International Technical Cooperation.

若昂-阿普里吉奥-格拉-德阿尔梅达教授(Joao Aprigio Guerra de Almeida)毕业于食品工程专业(UFV-1981 年),获得微生物学硕士学位(UFV-1986 年)和妇女儿童健康博士学位(Fiocruz/IFF,1998 年)。 他是巴西人乳库网络(巴西卫生部/Oswaldo Cruz 基金会-Fiocruz,1987 年至 2024 年)的创始人和协调人;国家妇女、儿童和青少年健康研究所 Fernandes Figueira-IFF 国家母乳库参考中心主任(Fiocruz/IFF,1987 年至 2024 年);伊比利亚-美洲母乳库网络计划执行秘书(伊比利亚-美洲总秘书处-SEGIB/巴西合作署-ABC/MS-FIOCRUZ,2008 至 2020 年);母乳库国际技术合作协调人 ABC/Fiocruz/MS(2005 至 2024 年);葡萄牙语国家共同体母乳库网络协调人 CPLP(2017 至 2024 年)。他曾荣获笹川健康奖(世界卫生组织[世卫组织],2001 年)、里约布兰科军官勋章(巴西联邦共和国总统,2001 年)、全球卫生挑战与危机时期南方的应对(世卫组织,2009 年)、里约布兰科勋章--巴西联邦共和国外交部/总统府嘉奖(2018 年)以及李钟郁博士公共卫生纪念奖(世卫组织,2020 年)。他的活动领域包括公共卫生、母乳喂养、母乳库、公共管理和国际技术合作。
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引用次数: 0
Shifting the Paradigm for Establishing and Maintaining Milk Production in the Setting of Mother/Infant Separation. 在母婴分离的情况下转变建立和维持母乳喂养的范式。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-23 DOI: 10.1177/08903344241278988
Claire Eden

Establishing lactation when mother and infant are separated, such as when the neonate is admitted to the neonatal intensive care unit (NICU), is challenging. The most common clinical advice is to express milk eight or more times per day, every 3 hours, around the clock. Sometimes, the first time that parents hear this is after the birth of their baby. This can be overwhelming and sometimes unachievable. A five-step paradigm shift is proposed that refocuses lactation care on providing evidence-based assistance and ongoing clinical education, and assessment beginning prenatally and extending past maternal discharge, to improve outcomes through curated support. Simple guidelines can begin with expressing milk at least five times a day by Day 5 of life (5 × 5), and expressing milk at least once between 0100 and 0500 (overnight pumping). With these measures, neonatal care in the NICU setting can provide personalized and achievable guidance on pumping schedules.

在母婴分离的情况下,如新生儿入住新生儿重症监护室(NICU)时,建立泌乳是一项挑战。最常见的临床建议是每天挤奶 8 次或更多,每 3 小时挤一次,全天候进行。有时,父母在孩子出生后才第一次听到这样的建议。这可能会让人不知所措,有时甚至无法实现。我们提出了五步模式转变,将哺乳护理的重点重新放在提供循证帮助、持续的临床教育和评估上,从产前开始,一直到产妇出院,通过持续的支持来改善结果。简单的指导原则可以从新生儿出生后第 5 天前每天至少挤奶 5 次(5 × 5),以及在 1 点至 5 点之间至少挤奶一次(隔夜泵奶)开始。有了这些措施,新生儿重症监护室的新生儿护理就能提供个性化和可实现的挤奶时间表指导。
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引用次数: 0
Response to Letter to the Editor. 回应致编辑的信。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2024-11-01 Epub Date: 2024-09-29 DOI: 10.1177/08903344241288410
Chele Marmet
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引用次数: 0
期刊
Journal of Human Lactation
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