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Journal of Magnetic Resonance, Series B最新文献

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A New Variant of the 3D PFG Homonuclear Double-Quantum Experiments with NOESY and TOCSY Steps 具有NOESY和TOCSY步骤的三维PFG同核双量子实验的新变体
Pub Date : 1996-08-01 DOI: 10.1006/jmrb.1996.0128
Claudio Dalvit
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引用次数: 1
Correlation-Peak Imaging 相关峰成像
Pub Date : 1996-08-01 DOI: 10.1006/jmrb.1996.0124
A. Ziegler , A. Metzler , W. Köckenberger , M. Izquierdo , E. Komor , A. Haase , M. Décorps , M. von Kienlin

Identification and quantitation in conventional1H spectroscopic imagingin vivois often hampered by the small chemical-shift range. To improve the spectral resolution of spectroscopic imaging, homonuclear two-dimensional correlation spectroscopy has been combined with phase encoding of the spatial dimensions. From the theoretical description of the coherence-transfer signal in the Fourier-transform domain, a comprehensive acquisition and processing strategy is presented that includes optimization of the width and the position of the acquisition windows, matched filtering of the signal envelope, and graphical presentation of the cross peak of interest. The procedure has been applied to image the spatial distribution of the correlation peaks from specific spin systems in the hypocotyl of castor bean (Ricinus communis) seedlings. Despite the overlap of many resonances, correlation-peak imaging made it possible to observe a number of proton resonances, such as those of sucrose, β-glucose, glutamine/glutamate, lysine, and arginine.

常规1h光谱成像在体内的鉴定和定量常常受到化学位移范围小的阻碍。为了提高光谱成像的光谱分辨率,将同核二维相关光谱与空间维度的相位编码相结合。从傅里叶变换域中相干转移信号的理论描述出发,提出了一种综合的采集和处理策略,包括采集窗口宽度和位置的优化、信号包络的匹配滤波以及感兴趣的交叉峰的图形表示。该方法已应用于蓖麻(Ricinus communis)幼苗下胚轴中特定自旋系统相关峰的空间分布成像。尽管有许多共振重叠,相关峰成像使得观察到一些质子共振成为可能,例如蔗糖、β-葡萄糖、谷氨酰胺/谷氨酸、赖氨酸和精氨酸。
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引用次数: 33
A Field-Gradient Coil Using Concentric Return Paths 使用同心返回路径的场梯度线圈
Pub Date : 1996-08-01 DOI: 10.1006/jmrb.1996.0122
William W. Brey, Thomas H. Mareci, Jerry Dougherty

An approach to transverse field-gradient coil design is presented which locates all current elements in planes perpendicular to the main magnetic field. The linear volume of the resulting coil structure can be made to extend nearly to both ends of the coil. This design is based on forming a concentric return path in the same plane as the field-producing arcs. The coil structure consists of stacked planar units which give a desired field-gradient configuration. The size of the linear-field region is optimized by varying the current in each plane, by varying the location of a plane relative to the others in the stack, or by varying both current and location. Coils with linear regions having a wide range of length-to-diameter ratios can be designed, as illustrated by two examples. The construction of a prototype coil is presented and its performance in imaging confirms the analysis. This type of design is suited to magnetic resonance of the human head without obstruction from the shoulders.

提出了一种横向场梯度线圈的设计方法,该方法将所有电流元件定位在与主磁场垂直的平面上。所得到的线圈结构的线性体积可以使其几乎延伸到线圈的两端。这种设计的基础是在与产油弧相同的平面上形成同心返回路径。线圈结构由堆叠的平面单元组成,这些单元提供了所需的场梯度配置。线性场区域的大小通过改变每个平面上的电流,通过改变一个平面相对于堆栈中其他平面的位置,或者通过改变电流和位置来优化。可以设计具有宽范围长径比的线性区域的线圈,如两个例子所示。给出了一个原型线圈的结构,其成像性能证实了分析结果。这种类型的设计适合于不受肩部阻碍的人类头部的磁共振。
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引用次数: 12
Verification of the Projection Resultant Method for Two-Bond13C–13C Coupling Sign Determinations in Carbohydrates 碳水化合物中二键13c - 13c偶联符号测定的投影合成法验证
Pub Date : 1996-07-01 DOI: 10.1006/jmrb.1996.0111
Anthony S. Serianni , Paul B. Bondo , Jaroslav Zajicek
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引用次数: 17
Amino-Acid-Type Identification for Deuterated Proteins with a β-Carbon-Edited HNCOCACB Experiment 用β-碳编辑HNCOCACB实验鉴定氘化蛋白的氨基酸型
Pub Date : 1996-07-01 DOI: 10.1006/jmrb.1996.0117
Volker Dötsch, Hiroshi Matsuo, Gerhard Wagner
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引用次数: 25
Proton Detection of Choline and Lactate in EMT6 Tumors by Spin-Echo-Enhanced Selective Multiple-Quantum-Coherence Transfer 利用自旋回波增强选择性多量子相干转移质子检测EMT6肿瘤中的胆碱和乳酸
Pub Date : 1996-07-01 DOI: 10.1006/jmrb.1996.0104
Qiuhong He , Zaver M. Bhujwalla, Jerry D. Glickson

An extension of the Sel-MQC pulse sequence—SEE-SelMQC (spin-echo-enhanced selective multiple-quantum coherence transfer)—that completely suppresses lipid and water in tissues containing mobile lipid in a single scan and detects1H resonances of multiple metabolites is described. As in the Sel-MQC lactate-editing experiments [Q. Heet al., J. Magn. Reson. B106, 203 (1995)], SEE-SelMQC acquires lactate from its ZQ → DQ coherence-transfer pathway; in addition, the method recovers signal from other metabolites by selective generation of additional spin echoes using extra frequency-selective pulses and gradients. This method introduces no loss of lactate signal intensity beyond the 50% that is lost through the multiple-quantum coherence-transfer process. The spatial distributions of choline and lactate with a phantom andin vivo,in subcutaneously implanted murine EMT6 tumors, have been simultaneously mapped.

selmqc脉冲序列的扩展- see - selmqc(自旋回波增强选择性多量子相干转移)-在单次扫描中完全抑制含有移动脂质的组织中的脂质和水,并检测多种代谢物的1h共振。在self - mqc乳酸编辑实验中[Q]。J. Magn。的原因。B106, 203 (1995)], SEE-SelMQC通过其ZQ→DQ相干转移途径获得乳酸;此外,该方法通过使用额外的频率选择脉冲和梯度选择性地产生额外的自旋回波,从其他代谢物中恢复信号。这种方法不引入乳酸信号强度的损失超过50%的损失是通过多量子相干转移过程。在皮下植入的小鼠EMT6肿瘤中,胆碱和乳酸的空间分布已被同时绘制。
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引用次数: 42
Application of the Quadrupolar Carr–Purcell–Meiboom–Gill Pulse Train for Sensitivity Enhancement in Deuteron NMR of Liquid Crystals 四极性carr - purcell - meiboomm - gill脉冲序列在液晶氘核磁共振灵敏度增强中的应用
Pub Date : 1996-07-01 DOI: 10.1006/jmrb.1996.0108
R.S. Prosser , N.J. Heaton , G. Kothe
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引用次数: 3
Carbon-Relayed Correlation of Intranucleotide Sugar H1′ and Base H6/H8 Protons in Oligonucleotides at Natural Abundance 天然丰度寡核苷酸中核苷酸内糖H1′和碱基H6/H8质子的碳传递相关性
Pub Date : 1996-07-01 DOI: 10.1006/jmrb.1996.0112
V.V. Krishnamurthy
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引用次数: 3
Simple, Distortion-Free Homonuclear Spectra of Peptides and Nucleic Acids in Water Using Excitation Sculpting 简单,无扭曲的多肽和核酸的同核光谱在水中使用激发雕刻
Pub Date : 1996-07-01 DOI: 10.1006/jmrb.1996.0114
Dana Callihan , John West , Surat Kumar , Barry I. Schweitzer , Timothy M. Logan
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引用次数: 31
High-Resolution Solid-State NMR Spectra of Integral Membrane Proteins Reconstituted into Magnetically Oriented Phospholipid Bilayers 整体膜蛋白重组成磁性磷脂双层的高分辨率固态核磁共振光谱
Pub Date : 1996-07-01 DOI: 10.1006/jmrb.1996.0116
Kathleen P. Howard, Stanley J. Opella
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引用次数: 80
期刊
Journal of Magnetic Resonance, Series B
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