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Heart failure misdiagnosed as acute cholecystitis: a case report. 心力衰竭误诊为急性胆囊炎:病例报告。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-16 DOI: 10.1186/s13256-024-04829-0
Qing Yu, Wen Lai

Background: Heart failure is a clinical syndrome characterized by decreased cardiac output, leading to systemic organ hypoxia and resulting in dyspnea, pulmonary edema, organ congestion, and pleural effusion. Owing to the diverse clinical manifestations of heart failure, early diagnosis can be challenging, and misdiagnosis may occur occasionally. The use of echocardiography and blood brain natriuretic peptide can aid in obtaining a more accurate diagnosis.

Case presentation: This article presents two case reports of patients who were misdiagnosed with acute cholecystitis. Both patients were young Mongolia males (age 26 and 39 years) who presented to the emergency department with acute upper abdominal pain, abdominal ultrasound revealed gallbladder enlargement, and blood tests suggested mild elevation of bilirubin levels. However, despite the absence of procalcitonin and C-reactive protein elevation, the patients were admitted to the general surgical department with a diagnosis of "acute cholecystitis." Both patients were given treatment for cholecystitis, but their vital signs did not improve, while later examinations confirmed heart failure. After treatment with diuretics and cardiac glycosides, both patients' symptoms were relieved.

Conclusion: We aim to highlight the clinical manifestations of heart failure and differentiate it from rare conditions such as acute cholecystitis. Physicians should make accurate diagnoses on the basis of physical examinations, laboratory testing and imaging, and surveys while avoiding diagnostic heuristics or mindsets. By sharing these two case reports, we hope to increase awareness to prevent potential complications and improve patient outcomes.

背景:心力衰竭是一种临床综合征,其特点是心输出量下降,导致全身器官缺氧,引起呼吸困难、肺水肿、器官充血和胸腔积液。由于心力衰竭的临床表现多种多样,因此早期诊断具有挑战性,误诊也偶有发生。使用超声心动图和血脑钠肽有助于获得更准确的诊断:本文报告了两例被误诊为急性胆囊炎的患者。两名患者均为蒙古族青年男性(26 岁和 39 岁),因急性上腹部疼痛到急诊科就诊,腹部超声波检查显示胆囊肿大,血液化验提示胆红素水平轻度升高。然而,尽管没有降钙素原和 C 反应蛋白升高,患者还是被送进了普通外科,诊断为 "急性胆囊炎"。两名患者都接受了胆囊炎治疗,但生命体征没有改善,后来的检查证实了心力衰竭。在接受利尿剂和强心苷治疗后,两名患者的症状均得到缓解:我们旨在强调心力衰竭的临床表现,并将其与急性胆囊炎等罕见疾病区分开来。医生应根据体格检查、实验室检测和影像学检查以及调查做出准确诊断,同时避免诊断启发式或思维定势。通过分享这两篇病例报告,我们希望提高人们的认识,预防潜在并发症,改善患者预后。
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引用次数: 0
Uncommon presentation of diffuse large B-cell lymphoma: oral and pulmonary involvements in a young patient: a case report. 弥漫大 B 细胞淋巴瘤的罕见表现:一名年轻患者的口腔和肺部受累:病例报告。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-16 DOI: 10.1186/s13256-024-04825-4
Fahimeh Rezazadeh, Zahra Mansouri, Asma Sookhakian, Vahid Mohammadkarimi

Background: Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphomas that remains a major diagnostic challenge due to the variety of its clinical presentations. This case highlights the importance of early biopsy of oral lesions without tendency to heal to attain the diagnosis more quickly. To the best of our knowledge, this study is the first to focus on both oral and pulmonary involvements in a patient with diffuse large B-cell lymphoma.

Case presentation: The presented case describes an Iranian 18-year-old girl with chronic cough and dyspnea referred for evaluation of the upper jaw due to bone exposure, bone loss, and soft tissue ulceration. Her medical history revealed mediastinal mass, cavitary lesion, and mediastinal lymphadenopathy. However, cytologic and immunohistochemical analysis did not show any evidence of malignancy. In this case a lymphoproliferative disease was suspected but ultimately the oral biopsy diagnosed diffuse large B-cell lymphoma and chemotherapy could be started.

Conclusions: Systemic conditions should be considered as a possible cause of oral lesions and a biopsy should also be performed immediately if there is any doubt concerning the nature of the lesion. Moreover, some conditions necessitate multiple biopsies to attain an accurate diagnosis.

背景:弥漫大 B 细胞淋巴瘤是非霍奇金淋巴瘤中最常见的亚型,由于其临床表现多种多样,因此仍然是诊断上的一大难题。本病例强调了对无愈合倾向的口腔病变进行早期活检以更快确诊的重要性。据我们所知,本研究是第一例同时关注弥漫大 B 细胞淋巴瘤患者口腔和肺部受累的病例:本病例描述的是一名患有慢性咳嗽和呼吸困难的 18 岁伊朗女孩,由于骨质暴露、骨质流失和软组织溃疡,她被转诊到医院对上颌骨进行评估。病史显示她有纵隔肿块、空洞性病变和纵隔淋巴结病。然而,细胞学和免疫组化分析并未显示任何恶性肿瘤的证据。该病例被怀疑患有淋巴增生性疾病,但最终口腔活检诊断为弥漫大 B 细胞淋巴瘤,并开始接受化疗:结论:全身性疾病应被视为口腔病变的可能原因,如果对病变的性质有任何怀疑,也应立即进行活检。此外,有些病症需要多次活检才能获得准确诊断。
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引用次数: 0
Incidental diagnosis of gastric antral vascular ectasia in a case of chronic kidney disease from Nepal: a case report. 尼泊尔一例慢性肾病患者被误诊为胃前庭血管异位症:病例报告。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-15 DOI: 10.1186/s13256-024-04813-8
Ashish Acharya, Kritika Bhattarai, Abashesh Bhandari

Introduction: Gastric antral vascular ectasia is an uncommon clinical disease that affects elder people and is characterized by severe chronic upper gastrointestinal bleeding mainly affecting the gastric antrum. It is generally unusual among patients undergoing maintenance hemodialysis for chronic kidney disease.

Case presentation: Here, we aim to present an uncommon case of incidental diagnosis of the gastric antral vascular ectasia and erosive gastritis in a 71-year-old Hindu male patient belonging to the Gurung ethnicity of Nepal undergoing maintenance hemodialysis due to chronic kidney disease. The patient presented with a history of melena and fatigue. On investigation, a low hemoglobin level of 7.3 gm% was used for blood transfusion. The patient was on regular hemodialysis after admission at our institution. Upper gastrointestinal bleeding was suspected after analyzing patient's history and investigations. Therefore, an upper gastrointestinal endoscopy was performed that showed linear ectatic punctuate lesions radiating from the body of the stomach to the antrum, and hence, an incidental diagnosis of the gastric antral vascular ectasia was made. Initial fluid resuscitation, iron therapy, and a triple regimen were administered. Proper management with argon plasma coagulation therapy was scheduled at another institution due to lack of respective facilities in our institution.

Discussion: Gastric antral vascular ectasia is an unusual cause of upper gastrointestinal bleeding, primarily affecting the gastric antrum and pylorus with rare cases affecting the duodenum, jejunum, and gastric fundus. It is generally associated with other chronic disease conditions. Several hypotheses have been proposed for the pathogenesis of gastric antral vascular ectasia, especially its association with chronic kidney disease, as in our case, which is considered to be rare. Management varies from medical to endoscopic interventions to even surgery.

Conclusion: Prompt proper diagnosis and treatment for the gastric antral vascular ectasia should be sought, as it is frequently misdiagnosed or missed during upper gastrointestinal endoscopy. Our case report presents a case of gastric antral vascular ectasia in chronic kidney disease undergoing maintenance hemodialysis, which is quite uncommon, as literature has suggested the same point.

简介胃窦部血管异位症是一种不常见的临床疾病,多发于老年人,主要表现为胃窦部严重的慢性上消化道出血。在接受维持性血液透析治疗的慢性肾病患者中,这种病一般并不常见:在此,我们旨在介绍一例罕见病例,该病例偶发诊断为胃窦前血管异位和糜烂性胃炎,患者为 71 岁印度教男性,尼泊尔古隆族,因慢性肾病接受维持性血液透析。患者有血便和乏力的病史。经检查,血红蛋白水平较低,仅为 7.3 gm%,需要输血。入院后,患者一直在接受定期血液透析。在分析了患者的病史和检查结果后,怀疑是上消化道出血。因此,对其进行了上消化道内镜检查,结果显示其胃体至胃窦呈线状异位点状病变,因此偶然诊断为胃窦血管异位。对患者进行了初步的液体复苏、铁剂治疗和三联疗法。由于本院缺乏相应的设施,因此安排在另一家医院进行氩等离子凝固治疗:讨论:胃前叶血管异位症是上消化道出血的一个不常见原因,主要影响胃窦和幽门,少数病例影响十二指肠、空肠和胃底。它通常与其他慢性疾病相关。关于胃窦部血管异位症的发病机理有几种假说,特别是与慢性肾脏病的关系,就像我们的病例一样,这被认为是罕见的。治疗方法多种多样,从药物治疗到内窥镜干预,甚至手术治疗:结论:胃前区血管异位症经常在上消化道内镜检查中被误诊或漏诊,因此应寻求及时正确的诊断和治疗。我们的病例报告介绍了一例接受维持性血液透析的慢性肾脏病患者的胃前庭血管异位,这在文献中并不常见。
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引用次数: 0
Delayed diagnosis and treatment of achalasia: a case report. 贲门失弛缓症的延迟诊断和治疗:病例报告。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-15 DOI: 10.1186/s13256-024-04717-7
Sabrina Ginsburg, Chelsea Caplan, Gauri Agarwal

Background: Achalasia is characterized as an esophageal motility disorder with incomplete relaxation of the lower esophageal sphincter. Achalasia can be associated with abnormal peristalsis and symptoms of dysphagia, acid reflux, and chest pain. The exact pathophysiology of achalasia remains unclear, but it is hypothesized to be due to degeneration of the myenteric plexus.

Case presentation: In this case, a 46-year-old Hispanic man presented to the emergency room with a 12-year history of progressive discomfort with swallowing solids and liquids. Due to many years of incomplete follow-up care and lack of understanding of the course of his disease, this patient's symptoms escalated to complete intolerance of oral intake and significant weight loss. He was diagnosed with achalasia during his hospital stay and treated successfully with laparoscopic Heller myotomy.

Conclusions: This case discussion illustrates the importance of follow-up care and patient education so that diagnosis and treatment of achalasia are not delayed.

背景:Achalasia 是一种食管运动障碍,表现为食管下括约肌不完全松弛。贲门失弛缓症可伴有异常蠕动以及吞咽困难、反酸和胸痛等症状。贲门失弛缓症的确切病理生理学尚不清楚,但推测是由于肠肌丛变性所致:在本病例中,一名 46 岁的西班牙裔男子因吞咽固体和液体时逐渐感到不适而到急诊室就诊,病史长达 12 年。由于多年未接受完整的后续治疗,加上对自己的病程缺乏了解,这名患者的症状升级为完全无法忍受口腔摄入,体重明显下降。住院期间,他被诊断为贲门失弛缓症,并成功接受了腹腔镜海勒肌切开术:本病例讨论说明了随访护理和患者教育的重要性,从而避免延误贲门失弛缓症的诊断和治疗。
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引用次数: 0
Successful management of acute left main coronary occlusion following transcatheter aortic valve implantation: a case report. 经导管主动脉瓣植入术后急性左主干冠状动脉闭塞的成功治疗:病例报告。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-15 DOI: 10.1186/s13256-024-04806-7
Georgi Goranov, Velina Doktorova

Background: Transcatheter aortic valve implantation is an established, highly effective procedure in selected patients with severe degenerative aortic valve stenosis at high risk for conventional surgery.

Case presentation: We report a case of a 74-year-old Caucasian man who had an acute left main occlusion after transcatheter implantation of balloon-expandable valve prosthesis, followed by coronary intervention with successful recanalization.

Conclusions: Acute coronary occlusion is a rare life-threatening complication of transcatheter aortic valve implantation that is poorly predictable and requires immediate diagnosis and treatment.

背景:经导管主动脉瓣植入术是一种成熟、高效的手术,适用于选定的严重退行性主动脉瓣狭窄、传统手术风险高的患者:我们报告了一例 74 岁高加索男性患者的病例,他在经导管植入球囊扩张瓣膜假体后发生急性左主干闭塞,随后接受冠状动脉介入治疗并成功再通畅:急性冠状动脉闭塞是经导管主动脉瓣植入术后一种罕见的危及生命的并发症,这种并发症很难预测,需要立即诊断和治疗。
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引用次数: 0
Rituximab induced cerebral venous sinus thrombosis in a patient with anti-N-methyl-D-aspartate receptor-antibody encephalitis: a case report and review of literature. 抗 N-甲基-D-天冬氨酸受体抗体脑炎患者利妥昔单抗诱发脑静脉窦血栓形成:病例报告和文献综述。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-14 DOI: 10.1186/s13256-024-04791-x
S Maathury, R Thevarajah, T Chang

Background: Cerebral venous sinus thrombosis has not been reported in anti-N-methyl-D-aspartate receptor-antibody encephalitis in the absence of an underlying thrombotic state while rituximab induced cerebral venous sinus thrombosis is rarely reported. We report a patient with anti-N-methyl-D-aspartate receptor-antibody encephalitis without a prothrombotic state who developed cerebral venous sinus thrombosis following rituximab treatment.

Case presentation: A 15-year-old Sri Lankan girl who had been in remission following an episode of anti-N-methyl-D-aspartate receptor-antibody encephalitis 2 years ago, presented with a relapse of anti-N-methyl-D-aspartate receptor-antibody encephalitis characterized by recurrent seizures, mutism, and cognitive abnormalities. Since response was inadequate to first-line immunotherapy, she was administered four doses of rituximab at weekly intervals. Two days after the fourth dose, she developed increasing headaches, and her cranial magnetic resonance venogram confirmed the development of cerebral venous sinus thrombosis. Screening for prothrombotic states were negative. She made an unremarkable recovery following anticoagulation.

Conclusion: This case highlights the occurrence of the rare but serious complication of cerebral venous sinus thrombosis following rituximab in the context of anti-N-methyl-D-aspartate receptor-antibody encephalitis and informs the clinician to be wary of new onset headache in patients with anti-N-methyl-D-aspartate receptor-antibody encephalitis treated with immunotherapy.

背景:抗-N-甲基-D-天冬氨酸受体抗体脑炎患者在没有潜在血栓形成状态的情况下,脑静脉窦血栓形成尚未见报道,而利妥昔单抗诱发脑静脉窦血栓形成的报道很少。我们报告了一名抗 N-甲基-D-天冬氨酸受体抗体脑炎患者,她在接受利妥昔单抗治疗后出现了脑静脉窦血栓:一名15岁的斯里兰卡女孩在两年前抗N-甲基-D-天冬氨酸受体抗体脑炎发作后病情得到缓解,后来抗N-甲基-D-天冬氨酸受体抗体脑炎复发,表现为反复发作、缄默和认知异常。由于对一线免疫疗法的反应不充分,她接受了四次利妥昔单抗治疗,每次间隔一周。第四剂后两天,她的头痛加剧,头颅磁共振静脉造影证实她患上了脑静脉窦血栓。血栓前状态筛查结果为阴性。抗凝治疗后,她恢复得很好:本病例强调了抗N-甲基-D-天冬氨酸受体抗体脑炎患者使用利妥昔单抗后发生脑静脉窦血栓形成这一罕见但严重的并发症,并提醒临床医生警惕接受免疫治疗的抗N-甲基-D-天冬氨酸受体抗体脑炎患者新发头痛。
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引用次数: 0
Management of scoliosis in a pediatric patient with lysyl hydroxylase-3 deficiency: a case report. 对患有赖氨酰羟化酶-3 缺乏症的儿童脊柱侧凸的治疗:病例报告。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-13 DOI: 10.1186/s13256-024-04822-7
Mirbahador Athari, Ardeshir Tajbakhsh, Ahmadreza Mirbolook, Maryamsadat Beheshtian, Mobin Forghan, Dariush Abtahi

Background: A rare case report of lysyl hydroxylases deficiency undergoing scoliosis surgery.

Case presentation: An 8-year-old Persian patient with a known case of lysyl hydroxylases deficiency presented with scoliosis. On physical examination, he had course facial hair, elbow flexion contracture, and knee flexion contracture. He had a history of eye surgery, clubfoot, and hearing problems. He underwent scoliosis surgery with growing rod instrumentation.

Conclusion: Surgery can be done in these patients with caution, and the surgeon and anesthesiologist should be aware of potential complications during and after surgery.

背景:一例罕见的赖氨酰羟化酶缺乏症脊柱侧弯手术病例:一例罕见的赖氨酰羟化酶缺乏症患者接受脊柱侧弯手术的病例报告:一名已知患有赖氨酰羟化酶缺乏症的 8 岁波斯病人因脊柱侧弯而就诊。体格检查时,他面部毛发稀疏,肘关节屈曲挛缩,膝关节屈曲挛缩。他有眼科手术史、马蹄内翻足和听力问题。他接受了脊柱侧弯手术,植入了生长棒器械:结论:这些患者可以谨慎进行手术,外科医生和麻醉师应注意术中和术后可能出现的并发症。
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引用次数: 0
Long-term outcome of adult traumatic atlantoaxial rotatory fixation: a case series. 成人外伤性寰枢椎旋转固定术的长期疗效:病例系列。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-11 DOI: 10.1186/s13256-024-04748-0
Keyvan Eghbal, Hamid Jangiaghdam, Saeed Tayebi Khorami, Amir Shabani Mayani, Bahram Seif, Sina Zoghi

Background: This case series presents five cases of adult atlantoaxial rotatory subluxation (AARS) following traumatic events, focusing on treatment strategies and long-term outcomes.

Case presentation: This paper includes four Iranian male patients and one Iranian female patient with ages ranging from 25 to 46 years old. Each case involved unique presentations and management approaches. Initial conservative treatments, including skull traction and orthoses, were attempted, but surgical intervention became necessary due to inadequate response. Surgical fixation significantly improved functional status and alleviated symptoms in all patients, leading to long-term relief. Radiological assessments demonstrated successful outcomes post-surgery.

Conclusions: This study underscores the importance of considering both conservative and surgical options in managing adult atlantoaxial rotatory subluxation to achieve optimal outcomes.

背景:本病例系列介绍了五例创伤后成人寰枢椎旋转半脱位(AARS)病例,重点关注治疗策略和长期疗效:本文包括四名伊朗籍男性患者和一名伊朗籍女性患者,年龄从 25 岁到 46 岁不等。每个病例都有独特的表现和治疗方法。最初尝试了包括颅骨牵引和矫形器在内的保守治疗,但由于疗效不佳,必须进行手术治疗。手术固定明显改善了所有患者的功能状态并减轻了症状,使病情得到长期缓解。放射学评估显示,手术后的治疗效果良好:这项研究强调,在治疗成人寰枢椎旋转脱位时,必须同时考虑保守治疗和手术治疗,以获得最佳疗效。
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引用次数: 0
Bilateral chronic cavitary pulmonary aspergillomas in an adult patient with recurrent tuberculosis: a case report and literature review. 一名复发性肺结核成年患者的双侧慢性腔隙性肺曲霉瘤:病例报告和文献综述。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-11 DOI: 10.1186/s13256-024-04801-y
Telila Mesfin Tadesse, Oliyad Shegene, Sisay Dadi Abebe, Eshetu Mesfin Tadesse, Biniyam Sahiledengle, Mesfin Tsegaye Jima

Background: Aspergillomas are globular growths of Aspergillus fumigatus, a benign aspergillosis of the lungs. It usually affects patients who are immunocompromised and have anatomically defective lung structures. The majority of aspergilloma cases are asymptomatic, despite the fact that 10% of cases spontaneously resolve. Most patients do not have any symptoms from their lesions. Direct serological or microbiological evidence of an Aspergillus species along with radiologic evidence is required for the diagnosis of an aspergilloma.

Case: We describe a 35-year-old adult Oromo male patient who had been experiencing night sweats, an intermittent productive cough with sparse whitish sputum, loss of appetite, and easy fatigability for 3 months. At 5 years prior, he received treatment for pulmonary tuberculosis that was smear-positive and was subsequently certified healed. Objectively, he was tachypneic and had intercostal, subcostal, and supraclavicular retractions with symmetric chest movement. A high-resolution computed tomography scan revealed bilateral apical cavitary lesions with core soft tissue attenuating spherical masses and an air crescentic sign suggestive of aspergillomas, which were confirmed by sputum light microscopic examination. The patient was managed with antibiotics and antifungals.

Conclusion: Aspergilloma is a symptom of chronic pulmonary aspergillosis, a category of lung disorders caused by a persistent Aspergillus infection. Primary aspergillomas are uncommon and frequently occur in people with compromised immune systems. A prolonged cough, fever, chest pain, and hemoptysis are all symptoms of pulmonary aspergillomas. The majority of the time, pulmonary aspergillosis is difficult to identify. Despite high mortality and morbidity rates, surgery is still the most effective treatment for pulmonary aspergilloma.

背景:曲霉瘤是烟曲霉菌的球状生长,是肺部的一种良性曲霉菌病。它通常影响免疫力低下和肺部结构有缺陷的患者。尽管有 10% 的病例会自发消退,但大多数曲霉瘤病例都没有症状。大多数患者的病变没有任何症状。曲霉瘤的诊断需要曲霉菌的直接血清学或微生物学证据以及放射学证据:我们描述了一名 35 岁的奥罗莫族成年男性患者,他盗汗、间歇性有痰咳嗽并伴有稀薄的白色痰液、食欲不振、易疲劳已持续 3 个月。5 年前,他曾因肺结核接受过治疗,涂片呈阳性,随后被证明痊愈。客观上,他呼吸急促,肋间、肋下和锁骨上回缩,胸部活动对称。高分辨率计算机断层扫描显示双侧肺尖腔病变,核心软组织衰减球形肿块和空气新月征提示曲霉瘤,痰液光镜检查证实了这一点。患者接受了抗生素和抗真菌药物治疗:曲霉瘤是慢性肺曲霉病的一种症状,慢性肺曲霉病是由曲霉菌持续感染引起的一类肺部疾病。原发性曲霉瘤并不常见,经常发生在免疫系统受损的人群中。长期咳嗽、发烧、胸痛和咯血都是肺曲霉瘤的症状。大多数情况下,肺曲霉菌病很难被发现。尽管死亡率和发病率都很高,但手术仍然是治疗肺曲霉瘤最有效的方法。
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引用次数: 0
Coronavirus-disease-2019-associated Stevens-Johnsons syndrome in a 15-year-old boy: a case report and review of the literature. 一名 15 岁男孩患冠状病毒病-2019 相关史蒂文斯-约翰逊综合征:病例报告和文献综述。
IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-10-11 DOI: 10.1186/s13256-024-04842-3
Na Li, Jian Li

Background: Stevens-Johnson syndrome (SJS) is a life-threatening condition characterized by high fever and severe mucocutaneous lesions, often triggered by drugs or infection. During the coronavirus disease 2019 pandemic, there was a marked increase in Stevens-Johnson syndrome cases, but relatively few cases were reported in children. The present article reports a pediatric case of Stevens-Johnson syndrome due to coronavirus disease 2019 infection and provides a review of the most relevant literature.

Case presentation: A previously healthy 15-year-old Han Chinese boy from China presented to the hospital with oral ulcers, conjunctival hyperemia, and widespread maculopapular rash. He had a history of fever 9 days prior and tested positive for coronavirus disease 2019 infection. Upon admission, his rash and mucosal lesions worsened, with the development of blisters on the fingertips of both hands, ocular pain, photophobia, and erosive lesions on the genital mucosa with exudation. He was diagnosed with Stevens-Johnson syndrome and received treatment with methylprednisolone, intravenous immunoglobulin, and dermatological and mucosal care. The patient's condition was managed, and the dosage of high-dose intravenous methylprednisolone was tapered down, followed by a transition to oral prednisolone. He was discharged without sequelae.

Conclusion: We should be aware that coronavirus disease 2019 infection is associated with the development of Stevens-Johnson syndrome in children and may lead to a wide spectrum of dermatologic presentations. Although Stevens-Johnson syndrome is a relatively rare condition, given its potentially serious consequences, it is crucial to identify it as early as possible and to take appropriate preventive and therapeutic measures to reduce complications and improve the quality of life for patients.

背景:史蒂文斯-约翰逊综合征(Stevens-Johnson syndrome,SJS)是一种危及生命的疾病,其特征是高烧和严重的皮肤黏膜病变,通常由药物或感染引发。在 2019 年冠状病毒病大流行期间,史蒂文斯-约翰逊综合征病例明显增加,但儿童病例报告相对较少。本文报告了一例因冠状病毒病2019年最新注册送彩金感染导致的史蒂文斯-约翰逊综合征儿科病例,并对最相关的文献进行了综述:一名来自中国的15岁汉族男孩因口腔溃疡、结膜充血和广泛的斑丘疹到医院就诊。他在 9 天前曾有发热史,2019 年冠状病毒病感染检测呈阳性。入院后,他的皮疹和粘膜病变加重,双手指尖出现水疱,眼部疼痛,畏光,生殖器粘膜出现糜烂和渗出。他被诊断为史蒂文斯-约翰逊综合征,并接受了甲基强的松龙、静脉注射免疫球蛋白以及皮肤和粘膜护理等治疗。患者的病情得到控制,大剂量静脉注射甲基强的松龙的剂量逐渐减少,随后转为口服强的松龙。他出院时没有留下后遗症:我们应该意识到,2019 年冠状病毒病感染与儿童史蒂文斯-约翰逊综合征的发生有关,并可能导致多种皮肤病表现。虽然史蒂文斯-约翰逊综合征是一种相对罕见的疾病,但鉴于其潜在的严重后果,尽早发现并采取适当的预防和治疗措施以减少并发症和提高患者的生活质量至关重要。
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引用次数: 0
期刊
Journal of Medical Case Reports
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